Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0141 | 0.9268 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0483 | 0.0483 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0141 | 0.9268 | 1 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0141 | 0.9268 | 0.9268 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0027 | 0 | 0.5 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0027 | 0 | 0.5 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0063 | 0.2919 | 0.2919 |
Schistosoma mansoni | tar DNA-binding protein | 0.0063 | 0.2919 | 0.2773 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0048 | 0.1721 | 0.1721 |
Schistosoma mansoni | tar DNA-binding protein | 0.0063 | 0.2919 | 0.2773 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0141 | 0.9268 | 1 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0141 | 0.9268 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0141 | 0.9268 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0141 | 0.9268 | 1 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0141 | 0.9268 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.015 | 1 | 1 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0141 | 0.9268 | 0.9268 |
Brugia malayi | RNA binding protein | 0.0063 | 0.2919 | 0.2919 |
Loa Loa (eye worm) | hypothetical protein | 0.0048 | 0.1721 | 0.1721 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0027 | 0 | 0.5 |
Leishmania major | hypothetical protein, conserved | 0.0027 | 0 | 0.5 |
Loa Loa (eye worm) | RNA binding protein | 0.0063 | 0.2919 | 0.2919 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0027 | 0 | 0.5 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0048 | 0.1721 | 0.1721 |
Schistosoma mansoni | tar DNA-binding protein | 0.0063 | 0.2919 | 0.2773 |
Onchocerca volvulus | 0.015 | 1 | 0.5 | |
Brugia malayi | RNA recognition motif domain containing protein | 0.0063 | 0.2919 | 0.2919 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0033 | 0.0483 | 0.0483 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0027 | 0 | 0.5 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0027 | 0 | 0.5 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0027 | 0 | 0.5 |
Brugia malayi | TAR-binding protein | 0.0063 | 0.2919 | 0.2919 |
Schistosoma mansoni | tar DNA-binding protein | 0.0063 | 0.2919 | 0.2773 |
Schistosoma mansoni | tar DNA-binding protein | 0.0063 | 0.2919 | 0.2773 |
Loa Loa (eye worm) | TAR-binding protein | 0.0063 | 0.2919 | 0.2919 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0048 | 0.1721 | 0.1721 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.