Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0021 | 0.0452 | 0.358 |
Schistosoma mansoni | coup transcription factor | 0.0161 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor E75 | 0.0076 | 0.4187 | 0.4033 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0047 | 0.2186 | 0.198 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0161 | 1 | 1 |
Echinococcus multilocularis | muscleblind protein 1 | 0.0152 | 0.9414 | 0.9399 |
Brugia malayi | hypothetical protein | 0.0076 | 0.4187 | 0.4033 |
Trypanosoma brucei | heat shock protein, putative | 0.0033 | 0.1263 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0161 | 1 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0161 | 1 | 1 |
Leishmania major | heat shock protein 83-1 | 0.0033 | 0.1263 | 1 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0161 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0076 | 0.4187 | 0.4033 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0021 | 0.0452 | 0.358 |
Echinococcus multilocularis | heat shock protein 90 | 0.0026 | 0.0801 | 0.0558 |
Loa Loa (eye worm) | hypothetical protein | 0.0076 | 0.4187 | 0.4033 |
Leishmania major | heat shock protein 83-1 | 0.0033 | 0.1263 | 1 |
Schistosoma mansoni | nuclear receptor nhr-48 | 0.0076 | 0.4187 | 0.4033 |
Giardia lamblia | Grp94/Hsp90 | 0.0026 | 0.0801 | 0.5409 |
Schistosoma mansoni | nuclear receptor | 0.0076 | 0.4187 | 0.4033 |
Echinococcus granulosus | nuclear receptor nhr 48 | 0.0076 | 0.4187 | 0.4033 |
Echinococcus multilocularis | heat shock protein | 0.0033 | 0.1263 | 0.1032 |
Trichomonas vaginalis | heat shock protein, putative | 0.0026 | 0.0801 | 0.5409 |
Trypanosoma brucei | heat shock protein, putative | 0.0033 | 0.1263 | 1 |
Echinococcus granulosus | heat shock protein 90 | 0.0033 | 0.1263 | 0.1032 |
Leishmania major | heat shock protein 83-1 | 0.0033 | 0.1263 | 1 |
Toxoplasma gondii | heat shock protein 90, putative | 0.0033 | 0.1263 | 1 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0161 | 1 | 1 |
Plasmodium falciparum | heat shock protein 90 | 0.0033 | 0.1263 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0021 | 0.0452 | 0.358 |
Schistosoma mansoni | zinc finger protein | 0.0076 | 0.4187 | 0.4033 |
Trypanosoma cruzi | heat shock protein 85, putative | 0.0026 | 0.0801 | 0.5409 |
Loa Loa (eye worm) | hypothetical protein | 0.0076 | 0.4187 | 0.4033 |
Loa Loa (eye worm) | hypothetical protein | 0.0085 | 0.4809 | 0.4672 |
Schistosoma mansoni | thyroid hormone receptor | 0.0161 | 1 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor-like 1 | 0.0085 | 0.4809 | 0.4672 |
Brugia malayi | nuclear receptor subfamily 1, group D, member 1, putative | 0.0076 | 0.4187 | 0.4033 |
Trypanosoma brucei | heat shock protein, putative | 0.0033 | 0.1263 | 1 |
Echinococcus multilocularis | nuclear receptor nhr 48 | 0.0076 | 0.4187 | 0.4033 |
Brugia malayi | nuclear receptor RXR | 0.0076 | 0.4187 | 0.4033 |
Loa Loa (eye worm) | hypothetical protein | 0.0161 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0161 | 1 | 1 |
Trypanosoma brucei | heat shock protein, putative | 0.0033 | 0.1263 | 1 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0021 | 0.0452 | 0.358 |
Trypanosoma cruzi | phosphatidylinositol kinase related protein, putative | 0.0018 | 0.0259 | 0.0024 |
Echinococcus granulosus | heat shock protein heat shock protein 90 alpha | 0.0026 | 0.0801 | 0.0558 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0025 | 0.0728 | 0.4685 |
Schistosoma mansoni | hepatocyte nuclear factor 4-alpha (hnf-4-alpha) | 0.0076 | 0.4187 | 0.4033 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0161 | 1 | 1 |
Trypanosoma brucei | heat shock protein, putative | 0.0033 | 0.1263 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0161 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0161 | 1 | 1 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0047 | 0.2186 | 0.198 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0161 | 1 | 1 |
Trichomonas vaginalis | heat shock protein, putative | 0.0026 | 0.0801 | 0.5409 |
Mycobacterium leprae | PROBABLE CHAPERONE PROTEIN HTPG (HEAT SHOCK PROTEIN) (HSP90 FAMILY PROTEIN) (HIGH TEMPERATURE PROTEIN G) | 0.0026 | 0.0801 | 0.5 |
Echinococcus granulosus | serine protein kinase ATM | 0.0025 | 0.0728 | 0.0484 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0047 | 0.2186 | 0.198 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0161 | 1 | 1 |
Leishmania major | heat shock protein 83-1 | 0.0033 | 0.1263 | 1 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0021 | 0.0452 | 0.1939 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0161 | 1 | 1 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.0076 | 0.4187 | 0.4033 |
Loa Loa (eye worm) | hypothetical protein | 0.0076 | 0.4187 | 0.4033 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0161 | 1 | 1 |
Brugia malayi | Phosphatidylinositol 3- and 4-kinase family protein | 0.0025 | 0.0728 | 0.0484 |
Leishmania major | heat shock protein 83-1 | 0.0033 | 0.1263 | 1 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0021 | 0.0452 | 0.1939 |
Echinococcus granulosus | heat shock protein | 0.0033 | 0.1263 | 0.1032 |
Leishmania major | heat shock protein 83-1 | 0.0033 | 0.1263 | 1 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0161 | 1 | 1 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.0076 | 0.4187 | 0.4033 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0021 | 0.0452 | 0.358 |
Trypanosoma brucei | Phosphatidylinositol 3-kinase tor1 | 0.0018 | 0.0257 | 0.2036 |
Brugia malayi | nuclear hormone receptor family member nhr-6 | 0.0076 | 0.4187 | 0.4033 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0161 | 1 | 1 |
Trichomonas vaginalis | heat shock protein, putative | 0.0026 | 0.0801 | 0.5409 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.0076 | 0.4187 | 0.4033 |
Echinococcus granulosus | dna polymerase eta | 0.0021 | 0.0452 | 0.02 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0076 | 0.4187 | 0.4033 |
Plasmodium vivax | endoplasmin, putative | 0.0033 | 0.1263 | 0.5 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0021 | 0.0452 | 0.358 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0047 | 0.2186 | 0.198 |
Trichomonas vaginalis | DNA polymerase eta, putative | 0.0021 | 0.0452 | 0.1939 |
Brugia malayi | hypothetical protein | 0.0076 | 0.4187 | 0.4033 |
Loa Loa (eye worm) | hypothetical protein | 0.0076 | 0.4187 | 0.4033 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.0161 | 1 | 1 |
Leishmania major | DNA polymerase kappa, putative,DNA polymerase IV, putative | 0.0021 | 0.0452 | 0.1939 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0161 | 1 | 1 |
Leishmania major | lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative | 0.0026 | 0.0801 | 0.5409 |
Leishmania major | heat shock protein 83-1 | 0.0033 | 0.1263 | 1 |
Giardia lamblia | Heat shock protein HSP 90-alpha | 0.0026 | 0.0801 | 0.5409 |
Trypanosoma brucei | heat shock protein, putative | 0.0033 | 0.1263 | 1 |
Trypanosoma cruzi | heat shock protein 85, putative | 0.0033 | 0.1263 | 1 |
Schistosoma mansoni | heat shock protein | 0.0033 | 0.1263 | 0.1032 |
Entamoeba histolytica | hypothetical protein | 0.0025 | 0.0728 | 0.4685 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0161 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0161 | 1 | 1 |
Loa Loa (eye worm) | nuclear receptor nhr-7B | 0.0076 | 0.4187 | 0.4033 |
Loa Loa (eye worm) | hypothetical protein | 0.0076 | 0.4187 | 0.4033 |
Schistosoma mansoni | endoplasmin | 0.0033 | 0.1263 | 0.1032 |
Trichomonas vaginalis | DNA polymerase IV / kappa, putative | 0.0021 | 0.0452 | 0.1939 |
Schistosoma mansoni | nuclear receptor | 0.0076 | 0.4187 | 0.4033 |
Trypanosoma cruzi | DNA polymerase eta, putative | 0.0021 | 0.0452 | 0.1939 |
Echinococcus multilocularis | dna polymerase eta | 0.0021 | 0.0452 | 0.02 |
Echinococcus multilocularis | endoplasmin | 0.0026 | 0.0801 | 0.0558 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0161 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0152 | 0.9414 | 0.9399 |
Echinococcus multilocularis | terminal deoxycytidyl transferase rev1 | 0.0021 | 0.0452 | 0.02 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.0021 | 0.0452 | 0.02 |
Leishmania major | heat shock protein 83-1 | 0.0033 | 0.1263 | 1 |
Trypanosoma brucei | heat shock protein 90, putative | 0.0033 | 0.1263 | 1 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0161 | 1 | 1 |
Loa Loa (eye worm) | heat shock protein 90 | 0.0033 | 0.1263 | 0.1032 |
Schistosoma mansoni | ataxia telangiectasia mutated (atm) | 0.0025 | 0.0728 | 0.0484 |
Leishmania major | heat shock protein 83-1 | 0.0033 | 0.1263 | 1 |
Echinococcus granulosus | muscleblind protein | 0.0152 | 0.9414 | 0.9399 |
Leishmania major | heat shock protein 83-1 | 0.0033 | 0.1263 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0161 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0085 | 0.4809 | 0.4672 |
Echinococcus multilocularis | heat shock protein 90 | 0.0033 | 0.1263 | 0.1032 |
Onchocerca volvulus | Bile acid receptor homolog | 0.0161 | 1 | 1 |
Plasmodium vivax | heat shock protein 86, putative | 0.0033 | 0.1263 | 0.5 |
Loa Loa (eye worm) | endoplasmin | 0.0033 | 0.1263 | 0.1032 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0161 | 1 | 1 |
Echinococcus granulosus | terminal deoxycytidyl transferase rev1 | 0.0021 | 0.0452 | 0.02 |
Echinococcus multilocularis | serine protein kinase ATM | 0.0025 | 0.0728 | 0.0484 |
Entamoeba histolytica | heat shock protein 90, putative | 0.0033 | 0.1263 | 1 |
Trypanosoma cruzi | phosphatidylinositol kinase related protein, putative | 0.0025 | 0.0728 | 0.4685 |
Brugia malayi | orphan nuclear receptor NR2E1 | 0.0076 | 0.4187 | 0.4033 |
Loa Loa (eye worm) | hypothetical protein | 0.0076 | 0.4187 | 0.4033 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0047 | 0.2186 | 0.198 |
Brugia malayi | heat shock protein 90 | 0.0033 | 0.1263 | 0.1032 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0161 | 1 | 1 |
Brugia malayi | steroid hormone receptor | 0.0161 | 1 | 1 |
Loa Loa (eye worm) | ImpB/MucB/SamB family protein | 0.0021 | 0.0452 | 0.02 |
Trypanosoma brucei | phosphatidylinositol 3-kinase, putative | 0.0018 | 0.0257 | 0.2036 |
Trypanosoma brucei | unspecified product | 0.0021 | 0.0452 | 0.358 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0161 | 1 | 1 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0021 | 0.0452 | 0.1939 |
Loa Loa (eye worm) | hypothetical protein | 0.0161 | 1 | 1 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0161 | 1 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0047 | 0.2186 | 0.198 |
Echinococcus multilocularis | nuclear receptor subfamily 4 group A | 0.0076 | 0.4187 | 0.4033 |
Loa Loa (eye worm) | hypothetical protein | 0.0076 | 0.4187 | 0.4033 |
Toxoplasma gondii | FATC domain-containing protein | 0.0025 | 0.0728 | 0.4685 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0021 | 0.0452 | 0.358 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0047 | 0.2186 | 0.198 |
Giardia lamblia | DINP protein human, muc B family | 0.0021 | 0.0452 | 0.1939 |
Schistosoma mansoni | ecdysone-induced protein 78c (dr-78) | 0.0085 | 0.4809 | 0.4672 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.0021 | 0.0452 | 0.02 |
Giardia lamblia | Heat shock protein HSP 90-alpha | 0.0033 | 0.1263 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0161 | 1 | 1 |
Schistosoma mansoni | rab geranylgeranyl transferase alpha subunit | 0.0021 | 0.0452 | 0.02 |
Echinococcus granulosus | dna polymerase kappa | 0.0021 | 0.0452 | 0.02 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0161 | 1 | 1 |
Echinococcus granulosus | nuclear receptor subfamily 4 group A | 0.0076 | 0.4187 | 0.4033 |
Loa Loa (eye worm) | hypothetical protein | 0.0076 | 0.4187 | 0.4033 |
Loa Loa (eye worm) | hypothetical protein | 0.0085 | 0.4809 | 0.4672 |
Trichomonas vaginalis | heat shock protein, putative | 0.002 | 0.0386 | 0.1285 |
Loa Loa (eye worm) | nuclear receptor NHR-67 | 0.0076 | 0.4187 | 0.4033 |
Echinococcus multilocularis | retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha | 0.0076 | 0.4187 | 0.4033 |
Trypanosoma brucei | Heat shock protein 83, putative | 0.0033 | 0.1263 | 1 |
Leishmania major | heat shock protein 83-1 | 0.0033 | 0.1263 | 1 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0161 | 1 | 1 |
Trypanosoma cruzi | heat shock protein 90, putative | 0.002 | 0.0334 | 0.0763 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0161 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor E75 | 0.0076 | 0.4187 | 0.4033 |
Schistosoma mansoni | thyroid hormone receptor | 0.0161 | 1 | 1 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0047 | 0.2186 | 0.198 |
Schistosoma mansoni | endoplasmin | 0.0033 | 0.1263 | 0.1032 |
Mycobacterium tuberculosis | Probable chaperone protein HtpG (heat shock protein) (HSP90 family protein) (high temperature protein G) | 0.0026 | 0.0801 | 1 |
Trichomonas vaginalis | endoplasmin, putative | 0.002 | 0.0386 | 0.1285 |
Trypanosoma cruzi | heat shock protein 90, putative | 0.0026 | 0.0801 | 0.5409 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0161 | 1 | 1 |
Trypanosoma brucei | target of rapamycin kinase 3, putative | 0.0018 | 0.0257 | 0.2036 |
Brugia malayi | tailless protein | 0.0076 | 0.4187 | 0.4033 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0021 | 0.0452 | 0.358 |
Loa Loa (eye worm) | hypothetical protein | 0.0085 | 0.4809 | 0.4672 |
Trypanosoma brucei | DNA polymerase eta, putative | 0.0021 | 0.0452 | 0.358 |
Leishmania major | heat shock protein 83-1 | 0.0033 | 0.1263 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor | 0.0076 | 0.4187 | 0.4033 |
Brugia malayi | nuclear receptor NHR-67 | 0.0076 | 0.4187 | 0.4033 |
Trypanosoma brucei | phosphatidylinositol 4-kinase, putative | 0.0018 | 0.0257 | 0.2036 |
Brugia malayi | nuclear receptor NHR-88 | 0.0076 | 0.4187 | 0.4033 |
Trypanosoma cruzi | heat shock protein 85, putative | 0.0033 | 0.1263 | 1 |
Brugia malayi | ecdysone receptor | 0.0076 | 0.4187 | 0.4033 |
Schistosoma mansoni | DNA polymerase eta | 0.0021 | 0.0452 | 0.02 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.0076 | 0.4187 | 0.4033 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0161 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0076 | 0.4187 | 0.4033 |
Leishmania major | heat shock protein 83-1 | 0.0033 | 0.1263 | 1 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0161 | 1 | 1 |
Schistosoma mansoni | nuclear hormone receptor | 0.0076 | 0.4187 | 0.4033 |
Trypanosoma brucei | heat shock protein 90, putative | 0.0033 | 0.1263 | 1 |
Leishmania major | heat shock protein 83-1 | 0.0033 | 0.1263 | 1 |
Brugia malayi | nuclear hormone receptor | 0.0161 | 1 | 1 |
Brugia malayi | nuclear hormone receptor family member odr-7 | 0.0076 | 0.4187 | 0.4033 |
Mycobacterium ulcerans | heat shock protein 90 | 0.0026 | 0.0801 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0161 | 1 | 1 |
Leishmania major | heat shock protein 83-1 | 0.0033 | 0.1263 | 1 |
Trypanosoma cruzi | heat shock protein 90, putative | 0.0033 | 0.1263 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0076 | 0.4187 | 0.4033 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0161 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0085 | 0.4809 | 0.4672 |
Leishmania major | phosphatidylinositol kinase related protein, putative | 0.0018 | 0.0259 | 0.0024 |
Leishmania major | DNA polymerase eta, putative | 0.0021 | 0.0452 | 0.1939 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0161 | 1 | 1 |
Schistosoma mansoni | nuclear hormone receptor | 0.0076 | 0.4187 | 0.4033 |
Loa Loa (eye worm) | hypothetical protein | 0.0152 | 0.9414 | 0.9399 |
Leishmania major | heat shock protein 83-1 | 0.0033 | 0.1263 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0085 | 0.4809 | 0.4672 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0161 | 1 | 1 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0161 | 1 | 1 |
Leishmania major | DNA polymerase kappa, putative | 0.0021 | 0.0452 | 0.1939 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0021 | 0.0452 | 0.358 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0485 | 0.0234 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0021 | 0.0452 | 0.1939 |
Loa Loa (eye worm) | hypothetical protein | 0.0076 | 0.4187 | 0.4033 |
Trypanosoma cruzi | heat shock protein 85, putative | 0.0033 | 0.1263 | 1 |
Echinococcus granulosus | nuclear receptor subfamily 1 group D | 0.0085 | 0.4809 | 0.4672 |
Trypanosoma brucei | heat shock protein, putative | 0.0033 | 0.1263 | 1 |
Schistosoma mansoni | nuclear hormone receptor | 0.0161 | 1 | 1 |
Echinococcus granulosus | FTZ F1 alpha | 0.0161 | 1 | 1 |
Brugia malayi | conserved hypotetical protein | 0.0076 | 0.4187 | 0.4033 |
Trichomonas vaginalis | heat shock protein, putative | 0.0033 | 0.1263 | 1 |
Wolbachia endosymbiont of Brugia malayi | heat shock protein 90 | 0.0026 | 0.0801 | 0.5 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0161 | 1 | 1 |
Schistosoma mansoni | heat shock protein | 0.0033 | 0.1263 | 0.1032 |
Trypanosoma brucei | heat shock protein, putative | 0.0033 | 0.1263 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0161 | 1 | 1 |
Echinococcus multilocularis | dna polymerase kappa | 0.0021 | 0.0452 | 0.02 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0161 | 1 | 1 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0161 | 1 | 1 |
Brugia malayi | nuclear hormone receptor | 0.0076 | 0.4187 | 0.4033 |
Trypanosoma cruzi | Heat shock protein 83, putative | 0.0033 | 0.1263 | 1 |
Echinococcus multilocularis | muscleblind protein | 0.0152 | 0.9414 | 0.9399 |
Trypanosoma cruzi | phosphatidylinositol kinase related protein, putative | 0.0022 | 0.0485 | 0.2272 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0076 | 0.4187 | 0.4033 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0161 | 1 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0047 | 0.2186 | 0.198 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0021 | 0.0452 | 0.358 |
Leishmania major | heat shock protein 83-1 | 0.0033 | 0.1263 | 1 |
Schistosoma mansoni | nuclear hormone receptor superfamily protein-related | 0.0076 | 0.4187 | 0.4033 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0085 | 0.4809 | 0.4672 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0452 | 0.02 |
Echinococcus multilocularis | nuclear receptor subfamily 1 group D | 0.0085 | 0.4809 | 0.4672 |
Brugia malayi | hypothetical protein | 0.0085 | 0.4809 | 0.4672 |
Entamoeba histolytica | deoxycytidyl transferase, putative | 0.0021 | 0.0452 | 0.1939 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0021 | 0.0452 | 0.358 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0161 | 1 | 1 |
Toxoplasma gondii | heat shock protein HSP90 | 0.0033 | 0.1263 | 1 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.0161 | 1 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0021 | 0.0452 | 0.358 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0161 | 1 | 1 |
Onchocerca volvulus | 0.0161 | 1 | 1 | |
Brugia malayi | nuclear receptor RXR | 0.0085 | 0.4809 | 0.4672 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0161 | 1 | 1 |
Loa Loa (eye worm) | DR-78 | 0.0076 | 0.4187 | 0.4033 |
Echinococcus granulosus | heat shock protein 90 | 0.0026 | 0.0801 | 0.0558 |
Treponema pallidum | heat shock protein 90 | 0.0026 | 0.0801 | 0.5 |
Echinococcus granulosus | endoplasmin | 0.0026 | 0.0801 | 0.0558 |
Schistosoma mansoni | terminal deoxycytidyl transferase | 0.0021 | 0.0452 | 0.02 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0161 | 1 | 1 |
Brugia malayi | Muscleblind-like protein | 0.0152 | 0.9414 | 0.9399 |
Entamoeba histolytica | heat shock protein 90, putative | 0.0033 | 0.1263 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0161 | 1 | 1 |
Brugia malayi | Endoplasmin precursor | 0.0033 | 0.1263 | 0.1032 |
Trypanosoma brucei | phosphatidylinositol kinase related protein, putative | 0.0025 | 0.0728 | 0.5767 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0161 | 1 | 1 |
Echinococcus granulosus | thyroid hormone receptor alpha | 0.0076 | 0.4187 | 0.4033 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0161 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0161 | 1 | 1 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0021 | 0.0452 | 0.358 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0085 | 0.4809 | 0.4672 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0161 | 1 | 1 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0161 | 1 | 1 |
Brugia malayi | hypothetical protein | 0.0085 | 0.4809 | 0.4672 |
Brugia malayi | nuclear receptor NHR-88 | 0.0161 | 1 | 1 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0161 | 1 | 1 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0161 | 1 | 1 |
Trypanosoma brucei | phosphatidylinositol 3-related kinase, putative | 0.0018 | 0.0257 | 0.2036 |
Loa Loa (eye worm) | hypothetical protein | 0.0076 | 0.4187 | 0.4033 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0161 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0161 | 1 | 1 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Potency (functional) | = 39.8107 um | PUBCHEM_BIOASSAY: qHTS Assay for the Inhibitors of Schistosoma Mansoni Peroxiredoxins. (Class of assay: confirmatory) [Related pubchem assays: 1011 (Confirmation Concentration-Response Assay for Inhibitors of the Schistosoma mansoni Redox Cascade ), 448 (Schistosoma Mansoni Peroxiredoxins (Prx2) and thioredoxin glutathione reductase (TGR) coupled assay)] | ChEMBL. | No reference |
Potency (binding) | = 44.6684 um | PUBCHEM_BIOASSAY: qHTS Assay for Identification of Novel General Anesthetics. In this assay, a GABAergic mimetic model system, apoferritin and a profluorescent 1-aminoanthracene ligand (1-AMA), was used to construct a competitive binding assay for identification of novel general anesthetics (Class of assay: confirmatory) [Related pubchem assays: 2385 (Probe Development Summary for Identification of Novel General Anesthetics), 2323 (Validation apoferritin assay run on SigmaAldrich LOPAC1280 collection)] | ChEMBL. | No reference |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.