Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | survival motor neuron protein | 0.0047 | 0.1089 | 0.1089 |
Schistosoma mansoni | cpg binding protein | 0.003 | 0.0648 | 0.0648 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0019 | 0.0389 | 0.0389 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0007 | 0.0074 | 0.0074 |
Mycobacterium leprae | Conserved hypothetical protein | 0.001 | 0.016 | 0.5 |
Brugia malayi | Cytochrome P450 family protein | 0.001 | 0.016 | 0.0081 |
Loa Loa (eye worm) | carboxylesterase | 0.0114 | 0.2801 | 0.4776 |
Brugia malayi | Carboxylesterase family protein | 0.0019 | 0.0389 | 0.0487 |
Echinococcus granulosus | para nitrobenzyl esterase | 0.0019 | 0.0389 | 0.0317 |
Echinococcus multilocularis | acetylcholinesterase | 0.0114 | 0.2801 | 0.2747 |
Onchocerca volvulus | 0.0047 | 0.1089 | 1 | |
Brugia malayi | hypothetical protein | 0.0019 | 0.0389 | 0.0487 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0389 | 0.0487 |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.0053 | 0.1242 | 1 |
Mycobacterium tuberculosis | Carboxylesterase LipT | 0.0019 | 0.0389 | 1 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0019 | 0.0377 | 0.0466 |
Schistosoma mansoni | hypothetical protein | 0.0398 | 1 | 1 |
Schistosoma mansoni | acetylcholinesterase | 0.0019 | 0.0389 | 0.0389 |
Brugia malayi | cytochrome P450 | 0.001 | 0.016 | 0.0081 |
Brugia malayi | Carboxylesterase family protein | 0.0019 | 0.0389 | 0.0487 |
Loa Loa (eye worm) | histone methyltransferase | 0.0009 | 0.0118 | 0.0005 |
Schistosoma mansoni | cpg binding protein | 0.0028 | 0.0608 | 0.0608 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.0009 | 0.0118 | 0.0044 |
Brugia malayi | Cytochrome P450 family protein | 0.0019 | 0.0377 | 0.0466 |
Trichomonas vaginalis | spcc417.12 protein, putative | 0.0019 | 0.0389 | 1 |
Brugia malayi | Carboxylesterase family protein | 0.0114 | 0.2801 | 0.4776 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0389 | 0.0487 |
Echinococcus granulosus | BC026374 protein S09 family | 0.0019 | 0.0389 | 0.0317 |
Echinococcus granulosus | family S9 non peptidase ue S09 family | 0.0019 | 0.0389 | 0.0317 |
Schistosoma mansoni | hypothetical protein | 0.001 | 0.016 | 0.016 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0059 | 0.1403 | 0.1403 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0389 | 0.0487 |
Trypanosoma brucei | cytochrome P450, putative | 0.0019 | 0.0377 | 1 |
Schistosoma mansoni | BC026374 protein (S09 family) | 0.0019 | 0.0389 | 0.0389 |
Echinococcus granulosus | carboxylesterase 5A | 0.0114 | 0.2801 | 0.2747 |
Echinococcus granulosus | acetylcholinesterase | 0.0114 | 0.2801 | 0.2747 |
Echinococcus multilocularis | survival motor neuron protein 1 | 0.023 | 0.5738 | 0.5706 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0114 | 0.2801 | 0.2801 |
Echinococcus granulosus | survival motor neuron protein 1 | 0.023 | 0.5738 | 0.5706 |
Brugia malayi | Carboxylesterase family protein | 0.0114 | 0.2801 | 0.4776 |
Brugia malayi | CXXC zinc finger family protein | 0.0028 | 0.0608 | 0.0876 |
Echinococcus granulosus | cpg binding protein | 0.003 | 0.0648 | 0.0578 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.0009 | 0.0118 | 0.0044 |
Loa Loa (eye worm) | carboxylesterase | 0.0019 | 0.0389 | 0.0487 |
Echinococcus multilocularis | neuroligin | 0.0019 | 0.0389 | 0.0317 |
Echinococcus granulosus | neuroligin | 0.0019 | 0.0389 | 0.0317 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0389 | 0.0487 |
Schistosoma mansoni | hypothetical protein | 0.0047 | 0.1089 | 0.1089 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0019 | 0.0389 | 1 |
Brugia malayi | Iron-sulfur cluster assembly accessory protein | 0.0047 | 0.1089 | 0.1733 |
Echinococcus granulosus | cytochrome P450 2K1 | 0.001 | 0.016 | 0.0087 |
Loa Loa (eye worm) | CYP4Cod1 | 0.0019 | 0.0377 | 0.0466 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0019 | 0.0389 | 1 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.0028 | 0.0608 | 0.0876 |
Echinococcus granulosus | acetylcholinesterase | 0.0114 | 0.2801 | 0.2747 |
Schistosoma mansoni | gliotactin | 0.0019 | 0.0389 | 0.0389 |
Trypanosoma cruzi | cytochrome P450, putative | 0.0019 | 0.0377 | 1 |
Mycobacterium ulcerans | carboxylesterase, LipT | 0.0019 | 0.0389 | 1 |
Echinococcus multilocularis | cpg binding protein | 0.003 | 0.0648 | 0.0578 |
Schistosoma mansoni | neuroligin 3 (S09 family) | 0.0019 | 0.0389 | 0.0389 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0019 | 0.0389 | 0.0389 |
Brugia malayi | Cytochrome P450 family protein | 0.0047 | 0.1103 | 0.1757 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0389 | 0.0487 |
Mycobacterium leprae | putative cytochrome p450 | 0.001 | 0.016 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0114 | 0.2801 | 0.4776 |
Brugia malayi | Cytochrome P450 family protein | 0.0019 | 0.0377 | 0.0466 |
Leishmania major | cytochrome p450-like protein | 0.0019 | 0.0377 | 1 |
Echinococcus multilocularis | acetylcholinesterase | 0.0114 | 0.2801 | 0.2747 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0047 | 0.1103 | 0.1757 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.0114 | 0.2801 | 0.4776 |
Echinococcus multilocularis | carboxylesterase 5A | 0.0114 | 0.2801 | 0.2747 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0019 | 0.0389 | 0.0389 |
Trypanosoma cruzi | cytochrome P450, putative | 0.0019 | 0.0377 | 1 |
Brugia malayi | Carboxylesterase family protein | 0.0019 | 0.0389 | 0.0487 |
Echinococcus multilocularis | family S9 non peptidase ue (S09 family) | 0.0019 | 0.0389 | 0.0317 |
Onchocerca volvulus | 0.0028 | 0.0608 | 0.3123 | |
Loa Loa (eye worm) | cytochrome P450 | 0.001 | 0.016 | 0.0081 |
Loa Loa (eye worm) | carboxylesterase | 0.0019 | 0.0389 | 0.0487 |
Schistosoma mansoni | cpg binding protein | 0.003 | 0.0648 | 0.0648 |
Schistosoma mansoni | cytochrome P450 | 0.001 | 0.016 | 0.016 |
Loa Loa (eye worm) | hypothetical protein | 0.023 | 0.5738 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0114 | 0.2801 | 0.4776 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0019 | 0.0377 | 0.0466 |
Mycobacterium ulcerans | cytochrome P450 185A4 Cyp185A4 | 0.0019 | 0.0377 | 0.9481 |
Brugia malayi | hypothetical protein | 0.023 | 0.5738 | 1 |
Brugia malayi | Carboxylesterase family protein | 0.0019 | 0.0389 | 0.0487 |
Echinococcus multilocularis | 0.001 | 0.016 | 0.0087 | |
Echinococcus multilocularis | para nitrobenzyl esterase | 0.0019 | 0.0389 | 0.0317 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0389 | 0.0487 |
Echinococcus multilocularis | BC026374 protein (S09 family) | 0.0019 | 0.0389 | 0.0317 |
Echinococcus multilocularis | dnaJ subfamily B | 0.0398 | 1 | 1 |
Trichomonas vaginalis | carboxylesterase domain containing protein, putative | 0.0019 | 0.0389 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0389 | 0.0487 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.