Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Toxoplasma gondii | LsmAD domain-containing protein | 0.0051 | 0.0869 | 0.5 |
Loa Loa (eye worm) | TAR-binding protein | 0.0131 | 0.4733 | 0.4637 |
Schistosoma mansoni | tar DNA-binding protein | 0.0131 | 0.4733 | 0.6965 |
Schistosoma mansoni | survival motor neuron protein | 0.0049 | 0.0779 | 0.092 |
Brugia malayi | Iron-sulfur cluster assembly accessory protein | 0.0049 | 0.0779 | 0.0779 |
Brugia malayi | RNA binding protein | 0.0131 | 0.4733 | 0.4733 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0051 | 0.0869 | 0.5 |
Schistosoma mansoni | thyroid hormone receptor | 0.0136 | 0.4975 | 0.7337 |
Loa Loa (eye worm) | hypothetical protein | 0.024 | 1 | 1 |
Echinococcus multilocularis | tar DNA binding protein | 0.0131 | 0.4733 | 0.0444 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0051 | 0.0869 | 0.5 |
Echinococcus granulosus | survival motor neuron protein 1 | 0.024 | 1 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0126 | 0.4488 | 0.6591 |
Loa Loa (eye worm) | RNA binding protein | 0.0131 | 0.4733 | 0.4637 |
Loa Loa (eye worm) | hypothetical protein | 0.0053 | 0.0992 | 0.083 |
Brugia malayi | hypothetical protein | 0.0051 | 0.0869 | 0.0869 |
Schistosoma mansoni | hypothetical protein | 0.0049 | 0.0779 | 0.092 |
Brugia malayi | TAR-binding protein | 0.0131 | 0.4733 | 0.4733 |
Schistosoma mansoni | hypothetical protein | 0.0172 | 0.6717 | 1 |
Leishmania major | hypothetical protein, conserved | 0.0051 | 0.0869 | 0.5 |
Onchocerca volvulus | 0.0049 | 0.0779 | 0.5 | |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0051 | 0.0869 | 0.5 |
Schistosoma mansoni | tar DNA-binding protein | 0.0131 | 0.4733 | 0.6965 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0051 | 0.0869 | 0.5 |
Schistosoma mansoni | tar DNA-binding protein | 0.0131 | 0.4733 | 0.6965 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.0869 | 0.0704 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0136 | 0.4975 | 0.0884 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0051 | 0.0869 | 0.5 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0131 | 0.4733 | 0.4637 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0053 | 0.0992 | 0.0992 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0036 | 0.0177 | 0.0177 |
Schistosoma mansoni | tar DNA-binding protein | 0.0131 | 0.4733 | 0.6965 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0053 | 0.0992 | 0.0992 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0131 | 0.4733 | 0.4733 |
Echinococcus multilocularis | geminin | 0.0172 | 0.6717 | 0.4044 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0053 | 0.0992 | 0.083 |
Echinococcus granulosus | tar DNA binding protein | 0.0131 | 0.4733 | 0.0444 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0051 | 0.0869 | 0.5 |
Echinococcus granulosus | geminin | 0.0172 | 0.6717 | 0.4044 |
Schistosoma mansoni | thyroid hormone receptor | 0.0136 | 0.4975 | 0.7337 |
Schistosoma mansoni | hypothetical protein | 0.0172 | 0.6717 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0131 | 0.4733 | 0.6965 |
Echinococcus multilocularis | survival motor neuron protein 1 | 0.024 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.