Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | coup transcription factor | 0.002 | 0.0643 | 0.0742 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0643 | 0.0643 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0061 | 0.0061 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.002 | 0.0643 | 0.0643 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.002 | 0.0643 | 0.0643 |
Loa Loa (eye worm) | nuclear hormone receptor-like 1 | 0.001 | 0.0061 | 0.0061 |
Schistosoma mansoni | nuclear hormone receptor | 0.002 | 0.0643 | 0.0742 |
Brugia malayi | nuclear receptor RXR | 0.001 | 0.0061 | 0.0061 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.002 | 0.0643 | 0.0742 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0138 | 0.8075 | 0.8075 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.002 | 0.0643 | 0.0643 |
Loa Loa (eye worm) | hypothetical protein | 0.0169 | 1 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.002 | 0.0643 | 0.0643 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.002 | 0.0643 | 0.0643 |
Brugia malayi | hypothetical protein | 0.001 | 0.0061 | 0.0061 |
Schistosoma mansoni | ecdysone-induced protein 78c (dr-78) | 0.001 | 0.0061 | 0.0071 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.002 | 0.0643 | 0.0643 |
Brugia malayi | nuclear receptor NHR-88 | 0.002 | 0.0643 | 0.0643 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.002 | 0.0643 | 0.0742 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0643 | 0.0643 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0643 | 0.0643 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.002 | 0.0643 | 0.0803 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.002 | 0.0643 | 0.0643 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.002 | 0.0643 | 0.0643 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.002 | 0.0643 | 0.0742 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.002 | 0.0643 | 0.0643 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.002 | 0.0643 | 0.0742 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0643 | 0.0643 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.002 | 0.0643 | 0.0643 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.002 | 0.0643 | 0.0742 |
Brugia malayi | hypothetical protein | 0.001 | 0.0061 | 0.0061 |
Brugia malayi | steroid hormone receptor | 0.002 | 0.0643 | 0.0643 |
Schistosoma mansoni | thyroid hormone receptor | 0.002 | 0.0643 | 0.0742 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.002 | 0.0643 | 0.0742 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0147 | 0.8663 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.002 | 0.0643 | 0.0643 |
Echinococcus multilocularis | FTZ F1 alpha | 0.002 | 0.0643 | 0.0803 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.002 | 0.0643 | 0.0643 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.002 | 0.0643 | 0.0742 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.002 | 0.0643 | 0.0643 |
Echinococcus multilocularis | retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha | 0.0137 | 0.8012 | 1 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.002 | 0.0643 | 0.0742 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.001 | 0.0061 | 0.0061 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.002 | 0.0643 | 0.0643 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.002 | 0.0643 | 0.0643 |
Echinococcus granulosus | FTZ F1 alpha | 0.002 | 0.0643 | 0.0742 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.001 | 0.0061 | 0.0061 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.002 | 0.0643 | 0.0803 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.002 | 0.0643 | 0.0643 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0061 | 0.0061 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0643 | 0.0643 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.002 | 0.0643 | 0.0742 |
Echinococcus multilocularis | nuclear receptor subfamily 1 group D | 0.001 | 0.0061 | 0.0076 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.002 | 0.0643 | 0.0742 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.001 | 0.0061 | 0.0071 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0643 | 0.0643 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0061 | 0.0061 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.002 | 0.0643 | 0.0803 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.002 | 0.0643 | 0.0643 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0061 | 0.0061 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.002 | 0.0643 | 0.0803 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.002 | 0.0643 | 0.0742 |
Schistosoma mansoni | thyroid hormone receptor | 0.002 | 0.0643 | 0.0742 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.002 | 0.0643 | 0.0643 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.002 | 0.0643 | 0.0742 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0061 | 0.0061 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.002 | 0.0643 | 0.0803 |
Brugia malayi | MH2 domain containing protein | 0.0138 | 0.8075 | 0.8075 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.002 | 0.0643 | 0.0643 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.002 | 0.0643 | 0.0643 |
Onchocerca volvulus | Bile acid receptor homolog | 0.0169 | 1 | 1 |
Loa Loa (eye worm) | steroid hormone receptor | 0.002 | 0.0643 | 0.0643 |
Echinococcus granulosus | nuclear receptor subfamily 1 group D | 0.001 | 0.0061 | 0.0071 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.002 | 0.0643 | 0.0803 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.002 | 0.0643 | 0.0803 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0138 | 0.8075 | 0.8075 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.002 | 0.0643 | 0.0643 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.002 | 0.0643 | 0.0742 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.002 | 0.0643 | 0.0742 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.002 | 0.0643 | 0.0803 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0643 | 0.0643 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0147 | 0.8663 | 1 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.002 | 0.0643 | 0.0742 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.002 | 0.0643 | 0.0643 |
Brugia malayi | nuclear hormone receptor | 0.002 | 0.0643 | 0.0643 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.002 | 0.0643 | 0.0643 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.