Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | acetylcholinesterase | 0.0132 | 1 | 1 |
Loa Loa (eye worm) | carboxylesterase | 0.0132 | 1 | 1 |
Entamoeba histolytica | tyrosyl-DNA phosphodiesterase, putative | 0.007 | 0.3197 | 0.5 |
Brugia malayi | Carboxylesterase family protein | 0.0132 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0132 | 1 | 1 |
Echinococcus granulosus | tyrosyl DNA phosphodiesterase 1 | 0.007 | 0.3197 | 0.3197 |
Schistosoma mansoni | tyrosyl-DNA phosphodiesterase | 0.007 | 0.3197 | 0.2552 |
Echinococcus multilocularis | tyrosyl DNA phosphodiesterase 1 | 0.007 | 0.3197 | 0.3197 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0048 | 0.0866 | 0.0866 |
Echinococcus multilocularis | carboxylesterase 5A | 0.0132 | 1 | 1 |
Trypanosoma cruzi | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.007 | 0.3197 | 0.5 |
Brugia malayi | Tyrosyl-DNA phosphodiesterase family protein | 0.007 | 0.3197 | 0.2552 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0132 | 1 | 1 |
Echinococcus granulosus | acetylcholinesterase | 0.0132 | 1 | 1 |
Trypanosoma cruzi | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.007 | 0.3197 | 0.5 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.0132 | 1 | 1 |
Trypanosoma brucei | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.007 | 0.3197 | 0.5 |
Echinococcus granulosus | acetylcholinesterase | 0.0132 | 1 | 1 |
Echinococcus multilocularis | acetylcholinesterase | 0.0132 | 1 | 1 |
Loa Loa (eye worm) | tyrosyl-DNA phosphodiesterase | 0.007 | 0.3197 | 0.2552 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0048 | 0.0866 | 0.0866 |
Loa Loa (eye worm) | hypothetical protein | 0.0132 | 1 | 1 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0048 | 0.0866 | 0.0866 |
Echinococcus granulosus | carboxylesterase 5A | 0.0132 | 1 | 1 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0048 | 0.0866 | 0.0866 |
Leishmania major | tyrosyl-DNA phosphodiesterase 1 | 0.007 | 0.3197 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.