Detailed information for compound 712094

Basic information

Technical information
  • TDR Targets ID: 712094
  • Name: propan-2-yl 3-amino-6-phenylthieno[5,4-b]pyri dine-2-carboxylate
  • MW: 312.386 | Formula: C17H16N2O2S
  • H donors: 1 H acceptors: 2 LogP: 4.72 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: CC(OC(=O)c1sc2c(c1N)ccc(n2)c1ccccc1)C
  • InChi: 1S/C17H16N2O2S/c1-10(2)21-17(20)15-14(18)12-8-9-13(19-16(12)22-15)11-6-4-3-5-7-11/h3-10H,18H2,1-2H3
  • InChiKey: FPTRIRLZNAUFJZ-UHFFFAOYSA-N  


Substructure search Similarity search

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Synonyms

  • isopropyl 3-amino-6-phenyl-thieno[5,4-b]pyridine-2-carboxylate
  • 3-amino-6-phenyl-2-thieno[5,4-b]pyridinecarboxylic acid isopropyl ester
  • 3-amino-6-phenyl-thieno[5,4-b]pyridine-2-carboxylic acid isopropyl ester
  • propan-2-yl 3-amino-6-phenyl-thieno[5,4-b]pyridine-2-carboxylate
  • MLS000581763
  • SMR000200288
  • isopropyl 3-amino-6-phenylthieno[2,3-b]pyridine-2-carboxylate
  • ZINC06238152

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens lysine (K)-specific methyltransferase 2A Starlite/ChEMBL No references
Homo sapiens survival of motor neuron 2, centromeric Starlite/ChEMBL No references
Bacillus subtilis (strain 168) ATP-dependent Clp protease proteolytic subunit Starlite/ChEMBL No references
Homo sapiens RAB9A, member RAS oncogene family Starlite/ChEMBL No references
Homo sapiens toll-like receptor 9 Starlite/ChEMBL No references
Homo sapiens cytochrome P450, family 2, subfamily C, polypeptide 19 Starlite/ChEMBL No references
Pseudomonas aeruginosa Beta Lactamase Starlite/ChEMBL No references
Homo sapiens Niemann-Pick disease, type C1 Starlite/ChEMBL No references
Homo sapiens multiple endocrine neoplasia I No references
Homo sapiens parathyroid hormone 1 receptor Starlite/ChEMBL No references
Homo sapiens geminin, DNA replication inhibitor Starlite/ChEMBL No references
Escherichia coli penicillin-binding protein Starlite/ChEMBL No references
Mus musculus heat shock factor 1 Starlite/ChEMBL No references
Homo sapiens chromobox homolog 1 Starlite/ChEMBL No references
Homo sapiens ATM serine/threonine kinase Starlite/ChEMBL No references
Homo sapiens ATPase family, AAA domain containing 5 Starlite/ChEMBL No references
Mus musculus RAR-related orphan receptor gamma Starlite/ChEMBL No references
Homo sapiens cytochrome P450, family 1, subfamily A, polypeptide 2 Starlite/ChEMBL No references
Rattus norvegicus Inositol monophosphatase 1 Starlite/ChEMBL No references
Homo sapiens glucagon-like peptide 1 receptor Starlite/ChEMBL No references
Homo sapiens ataxin 2 Starlite/ChEMBL No references
Photinus pyralis Luciferin 4-monooxygenase Starlite/ChEMBL No references
Homo sapiens microtubule-associated protein tau Starlite/ChEMBL No references
Homo sapiens cytochrome P450, family 2, subfamily C, polypeptide 9 Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Leishmania major 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Echinococcus granulosus serine protein kinase ATM Get druggable targets OG5_128955 All targets in OG5_128955
Candida albicans similar to putative phosphatidylinositol kinase involved in telomere length regulation Get druggable targets OG5_128955 All targets in OG5_128955
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative Get druggable targets OG5_126810 All targets in OG5_126810
Leishmania mexicana myo-inositol-1(or 4)-monophosphatase 1, putative Get druggable targets OG5_126810 All targets in OG5_126810
Mycobacterium ulcerans class a beta-lactamase, BlaC Get druggable targets OG5_143180 All targets in OG5_143180
Trypanosoma brucei phosphatidylinositol kinase related protein, putative Get druggable targets OG5_128955 All targets in OG5_128955
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) Get druggable targets OG5_126609 All targets in OG5_126609
Onchocerca volvulus Heat shock factor protein 2 homolog Get druggable targets OG5_129203 All targets in OG5_129203
Echinococcus granulosus survival motor neuron protein 1 Get druggable targets OG5_132873 All targets in OG5_132873
Babesia bovis ATP-dependent Clp protease proteolytic subunit 1, putative Get druggable targets OG5_127187 All targets in OG5_127187
Schistosoma japonicum ko:K04728 ataxia telangectasia mutated family protein, putative Get druggable targets OG5_128955 All targets in OG5_128955
Echinococcus granulosus chromobox protein 1 Get druggable targets OG5_129545 All targets in OG5_129545
Echinococcus granulosus expressed conserved protein Get druggable targets OG5_128206 All targets in OG5_128206
Candida albicans similar to S. cerevisiae Heat Shock Factor HSF1 (YGL073W) RNA Pol II transcriptional activator Get druggable targets OG5_129203 All targets in OG5_129203
Theileria parva hypothetical protein Get druggable targets OG5_129545 All targets in OG5_129545
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative Get druggable targets OG5_126810 All targets in OG5_126810
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit Get druggable targets OG5_127187 All targets in OG5_127187
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania mexicana 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Echinococcus multilocularis expressed conserved protein Get druggable targets OG5_128206 All targets in OG5_128206
Candida albicans potential membrane protein similar to S. cerevisiae NCR1 (YPL006W) and human NPC1 late endosomal protein involved in sterol home Get druggable targets OG5_128206 All targets in OG5_128206
Neospora caninum phosphatidylinositol 3- and 4-kinase domain- containing protein, putative Get druggable targets OG5_128955 All targets in OG5_128955
Schistosoma japonicum ko:K07003 Niemann Pick type C1, putative Get druggable targets OG5_128206 All targets in OG5_128206
Leishmania braziliensis myo-inositol-1(or 4)-monophosphatase 1, putative Get druggable targets OG5_126810 All targets in OG5_126810
Schistosoma japonicum Niemann-Pick C1 protein precursor, putative Get druggable targets OG5_128206 All targets in OG5_128206
Schistosoma mansoni inositol monophosphatase Get druggable targets OG5_126810 All targets in OG5_126810
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Get druggable targets OG5_126609 All targets in OG5_126609
Entamoeba histolytica heat shock transcription factor, putative Get druggable targets OG5_129203 All targets in OG5_129203
Plasmodium vivax acyl-CoA synthetase, putative Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania infantum 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Echinococcus multilocularis survival motor neuron protein 1 Get druggable targets OG5_132873 All targets in OG5_132873
Entamoeba histolytica myo-inositol monophosphatase, putative Get druggable targets OG5_126810 All targets in OG5_126810
Mycobacterium ulcerans extragenic suppressor protein SuhB Get druggable targets OG5_126810 All targets in OG5_126810
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core Get druggable targets OG5_139225 All targets in OG5_139225
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_129545 All targets in OG5_129545
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_132873 All targets in OG5_132873
Trichomonas vaginalis chromobox protein, putative Get druggable targets OG5_129545 All targets in OG5_129545
Mycobacterium ulcerans long-chain fatty-acid CoA ligase Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium ulcerans acyl-CoA synthetase Get druggable targets OG5_126609 All targets in OG5_126609
Schistosoma japonicum ko:K04380 microtubule-associated protein tau, putative Get druggable targets OG5_133504 All targets in OG5_133504
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase Get druggable targets OG5_126609 All targets in OG5_126609
Echinococcus granulosus Niemann Pick C1 protein Get druggable targets OG5_128206 All targets in OG5_128206
Toxoplasma gondii FATC domain-containing protein Get druggable targets OG5_128955 All targets in OG5_128955
Schistosoma japonicum hypothetical protein Get druggable targets OG5_128955 All targets in OG5_128955
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) Get druggable targets OG5_126609 All targets in OG5_126609
Echinococcus granulosus peptidase Clp S14 family Get druggable targets OG5_127187 All targets in OG5_127187
Leishmania mexicana 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Trichomonas vaginalis chromobox protein, putative Get druggable targets OG5_129545 All targets in OG5_129545
Entamoeba histolytica heat shock transcription factor, putative Get druggable targets OG5_129203 All targets in OG5_129203
Plasmodium berghei ATP-dependent Clp protease proteolytic subunit, putative Get druggable targets OG5_127187 All targets in OG5_127187
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128206 All targets in OG5_128206
Schistosoma mansoni ataxia telangiectasia mutated (atm) Get druggable targets OG5_128955 All targets in OG5_128955
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) Get druggable targets OG5_127187 All targets in OG5_127187
Neospora caninum ATP-dependent Clp protease proteolytic subunit, related Get druggable targets OG5_127187 All targets in OG5_127187
Onchocerca volvulus Get druggable targets OG5_129545 All targets in OG5_129545
Echinococcus multilocularis chromobox protein 1 Get druggable targets OG5_129545 All targets in OG5_129545
Schistosoma mansoni chromobox protein Get druggable targets OG5_129545 All targets in OG5_129545
Schistosoma japonicum Niemann-Pick C1 protein precursor, putative Get druggable targets OG5_128206 All targets in OG5_128206
Echinococcus multilocularis Niemann Pick C1 protein Get druggable targets OG5_128206 All targets in OG5_128206
Schistosoma japonicum ko:K09188 myeloid/lymphoid or mixed-lineage leukemia protein 3, putative Get druggable targets OG5_130642 All targets in OG5_130642
Schistosoma japonicum ko:K06275 parvin, putative Get druggable targets OG5_127187 All targets in OG5_127187
Leishmania donovani myo-inositol-1(or 4)-monophosphatase 1, putative Get druggable targets OG5_126810 All targets in OG5_126810
Wolbachia endosymbiont of Brugia malayi ATP-dependent Clp protease proteolytic subunit Get druggable targets OG5_127187 All targets in OG5_127187
Trichomonas vaginalis chromobox protein, putative Get druggable targets OG5_129545 All targets in OG5_129545
Mycobacterium ulcerans acyl-CoA synthetase Get druggable targets OG5_126609 All targets in OG5_126609
Echinococcus granulosus microtubule associated protein 2 Get druggable targets OG5_133504 All targets in OG5_133504
Entamoeba histolytica acyl-CoA synthetase, putative Get druggable targets OG5_126609 All targets in OG5_126609
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128206 All targets in OG5_128206
Plasmodium yoelii ATP-dependent Clp protease, proteolytic subunit ClpP, putative Get druggable targets OG5_127187 All targets in OG5_127187
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) Get druggable targets OG5_127187 All targets in OG5_127187
Loa Loa (eye worm) heterochromatin protein 1 Get druggable targets OG5_129545 All targets in OG5_129545
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative Get druggable targets OG5_127187 All targets in OG5_127187
Leishmania infantum 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium ulcerans hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Get druggable targets OG5_126609 All targets in OG5_126609
Loa Loa (eye worm) cytochrome P450 family protein Get druggable targets OG5_126582 All targets in OG5_126582
Loa Loa (eye worm) inositol-1 Get druggable targets OG5_126810 All targets in OG5_126810
Brugia malayi Inositol-1 Get druggable targets OG5_126810 All targets in OG5_126810
Onchocerca volvulus Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania infantum myo-inositol-1(or 4)-monophosphatase 1, putative Get druggable targets OG5_126810 All targets in OG5_126810
Treponema pallidum ATP-dependent Clp protease proteolytic subunit Get druggable targets OG5_127187 All targets in OG5_127187
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Get druggable targets OG5_126609 All targets in OG5_126609
Brugia malayi AMP-binding enzyme family protein Get druggable targets OG5_126609 All targets in OG5_126609
Brugia malayi Probable ClpP-like protease Get druggable targets OG5_127187 All targets in OG5_127187
Echinococcus multilocularis inositol monophosphatase 1 Get druggable targets OG5_126810 All targets in OG5_126810
Echinococcus granulosus Niemann Pick C1 protein Get druggable targets OG5_128206 All targets in OG5_128206
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase Get druggable targets OG5_126810 All targets in OG5_126810
Echinococcus multilocularis ATP dependent Clp protease proteolytic subunit Get druggable targets OG5_127187 All targets in OG5_127187
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein Get druggable targets OG5_127187 All targets in OG5_127187
Neospora caninum hypothetical protein Get druggable targets OG5_126810 All targets in OG5_126810
Leishmania infantum 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit Get druggable targets OG5_127187 All targets in OG5_127187
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128955 All targets in OG5_128955
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_129203 All targets in OG5_129203
Entamoeba histolytica acyl-coA synthetase, putative Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania major 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase Get druggable targets OG5_126609 All targets in OG5_126609
Echinococcus multilocularis chromobox protein 1 Get druggable targets OG5_129545 All targets in OG5_129545
Echinococcus multilocularis dnaJ subfamily B Get druggable targets OG5_133913 All targets in OG5_133913
Leishmania mexicana 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Get druggable targets OG5_126609 All targets in OG5_126609
Candida albicans similar to S. cerevisiae Heat Shock Factor HSF1 (YGL073W) RNA Pol II transcriptional activator Get druggable targets OG5_129203 All targets in OG5_129203
Candida albicans identical to the C terminus of CaP19.5580 potential phosphatidylinositol kinase Get druggable targets OG5_128955 All targets in OG5_128955
Schistosoma japonicum ko:K01358 ATP-dependent Clp protease, protease subunit [EC3.4.21.92], putative Get druggable targets OG5_127187 All targets in OG5_127187
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein Get druggable targets OG5_128955 All targets in OG5_128955
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative Get druggable targets OG5_128955 All targets in OG5_128955
Leishmania major phosphatidylinositol kinase related protein, putative Get druggable targets OG5_128955 All targets in OG5_128955
Mycobacterium tuberculosis Class a beta-lactamase BlaC Get druggable targets OG5_143180 All targets in OG5_143180
Mycobacterium tuberculosis Possible penicillin-binding protein Get druggable targets OG5_149948 All targets in OG5_149948
Entamoeba histolytica Niemann-Pick C1 protein, putative Get druggable targets OG5_128206 All targets in OG5_128206
Trichomonas vaginalis myo inositol monophosphatase, putative Get druggable targets OG5_126810 All targets in OG5_126810
Trypanosoma congolense inositol-1(or 4)-monophosphatase 1, putative Get druggable targets OG5_126810 All targets in OG5_126810
Entamoeba histolytica acyl-CoA synthetase, putative Get druggable targets OG5_126609 All targets in OG5_126609
Plasmodium falciparum acyl-CoA synthetase Get druggable targets OG5_126609 All targets in OG5_126609
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_127187 All targets in OG5_127187
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) Get druggable targets OG5_127187 All targets in OG5_127187
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) Get druggable targets OG5_127187 All targets in OG5_127187
Leishmania braziliensis 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Schistosoma japonicum ko:K01092 myo-inositol-1(or 4)-monophosphatase [EC3.1.3.25], putative Get druggable targets OG5_126810 All targets in OG5_126810
Brugia malayi hypothetical protein Get druggable targets OG5_132873 All targets in OG5_132873
Schistosoma mansoni inositol monophosphatase Get druggable targets OG5_126810 All targets in OG5_126810
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative Get druggable targets OG5_126810 All targets in OG5_126810
Schistosoma mansoni peptidase Clp (S14 family) Get druggable targets OG5_127187 All targets in OG5_127187
Schistosoma japonicum ko:K04588 secretin receptor, putative Get druggable targets OG5_139196 All targets in OG5_139196
Leishmania infantum phosphatidylinositol kinase related protein, putative Get druggable targets OG5_128955 All targets in OG5_128955
Mycobacterium ulcerans acyl-CoA synthetase Get druggable targets OG5_126609 All targets in OG5_126609
Brugia malayi AMP-binding enzyme family protein Get druggable targets OG5_126609 All targets in OG5_126609
Brugia malayi Heterochromatin protein 1 Get druggable targets OG5_129545 All targets in OG5_129545
Entamoeba histolytica hypothetical protein Get druggable targets OG5_128955 All targets in OG5_128955
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). Get druggable targets OG5_126810 All targets in OG5_126810
Schistosoma japonicum hypothetical protein Get druggable targets OG5_128955 All targets in OG5_128955
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative Get druggable targets OG5_126810 All targets in OG5_126810
Candida albicans similar to putative phosphatidylinositol kinase involved in telomere length regulation Get druggable targets OG5_128955 All targets in OG5_128955
Echinococcus multilocularis microtubule associated protein 2 Get druggable targets OG5_133504 All targets in OG5_133504
Entamoeba histolytica heat shock transcription factor, putative Get druggable targets OG5_129203 All targets in OG5_129203
Brugia malayi AMP-binding enzyme family protein Get druggable targets OG5_126609 All targets in OG5_126609
Echinococcus granulosus ATP dependent Clp protease proteolytic subunit Get druggable targets OG5_127187 All targets in OG5_127187
Schistosoma japonicum Menin, putative Get druggable targets OG5_133913 All targets in OG5_133913
Plasmodium yoelii peroxisomal-coenzyme a synthetase Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania donovani 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Onchocerca volvulus Heterochromatin protein 1 homolog Get druggable targets OG5_129545 All targets in OG5_129545
Plasmodium berghei acyl-CoA synthetase, putative Get druggable targets OG5_126609 All targets in OG5_126609
Schistosoma japonicum Chromobox protein homolog 5, putative Get druggable targets OG5_129545 All targets in OG5_129545
Leishmania donovani phosphatidylinositol 3-kinase-like protein Get druggable targets OG5_128955 All targets in OG5_128955
Trichomonas vaginalis chromobox protein, putative Get druggable targets OG5_129545 All targets in OG5_129545
Mycobacterium ulcerans fatty-acid-CoA ligase Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit Get druggable targets OG5_127187 All targets in OG5_127187
Echinococcus granulosus dnaJ subfamily B Get druggable targets OG5_133913 All targets in OG5_133913
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative Get druggable targets OG5_126810 All targets in OG5_126810
Brugia malayi Niemann-Pick C1 protein precursor Get druggable targets OG5_128206 All targets in OG5_128206
Plasmodium knowlesi acyl-CoA synthetase, putative Get druggable targets OG5_126609 All targets in OG5_126609
Schistosoma mansoni chromobox protein Get druggable targets OG5_129545 All targets in OG5_129545
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein Get druggable targets OG5_127187 All targets in OG5_127187
Brugia malayi Cytochrome P450 family protein Get druggable targets OG5_126582 All targets in OG5_126582
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase Get druggable targets OG5_126609 All targets in OG5_126609
Trypanosoma brucei gambiense inositol-1(or 4)-monophosphatase 1, putative Get druggable targets OG5_126810 All targets in OG5_126810
Echinococcus multilocularis peptidase Clp (S14 family) Get druggable targets OG5_127187 All targets in OG5_127187
Leishmania infantum 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Toxoplasma gondii histone lysine methyltransferase SET1 Get druggable targets OG5_130642 All targets in OG5_130642
Theileria parva ATP-dependent Clp protease proteolytic subunit, putative Get druggable targets OG5_127187 All targets in OG5_127187
Leishmania major 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Schistosoma japonicum IPR000971,Globin;IPR012292,Globin-related;IPR009050,Globin-like,domain-containing Get druggable targets OG5_128955 All targets in OG5_128955
Echinococcus granulosus chromobox protein 1 Get druggable targets OG5_129545 All targets in OG5_129545
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB Get druggable targets OG5_126810 All targets in OG5_126810
Neospora caninum Multidomain chromatinic protein with the following architecture: 3x PHD-bromo-3xPHD-SET domain and associated cysteine cluster a Get druggable targets OG5_130642 All targets in OG5_130642
Echinococcus granulosus inositol monophosphatase 1 Get druggable targets OG5_126810 All targets in OG5_126810
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium ulcerans fatty-acid-CoA ligase Get druggable targets OG5_126609 All targets in OG5_126609
Schistosoma mansoni hypothetical protein Get druggable targets OG5_133913 All targets in OG5_133913
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit Get druggable targets OG5_127187 All targets in OG5_127187
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Theileria parva ATP-dependent Clp protease proteolytic subunit, putative Get druggable targets OG5_127187 All targets in OG5_127187
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Plasmodium knowlesi ATP-dependent Clp protease proteolytic subunit, putative Get druggable targets OG5_127187 All targets in OG5_127187
Leishmania mexicana phosphatidylinositol 3-kinase-like protein Get druggable targets OG5_128955 All targets in OG5_128955
Leishmania donovani 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Trichomonas vaginalis inositol monophosphatase, putative Get druggable targets OG5_126810 All targets in OG5_126810
Schistosoma mansoni microtubule-associated protein tau Get druggable targets OG5_133504 All targets in OG5_133504
Leishmania braziliensis phosphatidylinositol kinase related protein, putative Get druggable targets OG5_128955 All targets in OG5_128955
Brugia malayi HSF-type DNA-binding domain containing protein Get druggable targets OG5_129203 All targets in OG5_129203
Echinococcus multilocularis serine protein kinase ATM Get druggable targets OG5_128955 All targets in OG5_128955
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit Get druggable targets OG5_127187 All targets in OG5_127187
Trypanosoma brucei gambiense phosphatidylinositol kinase domain protein, putative Get druggable targets OG5_128955 All targets in OG5_128955
Schistosoma mansoni mixed-lineage leukemia protein mll Get druggable targets OG5_130642 All targets in OG5_130642
Trichomonas vaginalis myo inositol monophosphatase, putative Get druggable targets OG5_126810 All targets in OG5_126810
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Get druggable targets OG5_126609 All targets in OG5_126609
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative Get druggable targets OG5_128955 All targets in OG5_128955
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative Get druggable targets OG5_128955 All targets in OG5_128955
Echinococcus multilocularis Niemann Pick C1 protein Get druggable targets OG5_128206 All targets in OG5_128206
Trichomonas vaginalis PIKK family atypical protein kinase Get druggable targets OG5_128955 All targets in OG5_128955
Schistosoma mansoni niemann-pick C1 (NPC1) Get druggable targets OG5_128206 All targets in OG5_128206
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 493 aa 20.7 %
Entamoeba histolytica 3(2),5-bisphosphate nucleotidase, putative Inositol monophosphatase 1   277 aa 287 aa 22.3 %
Dictyostelium discoideum acetyl-CoA ligase Luciferin 4-monooxygenase   550 aa 549 aa 22.2 %
Theileria parva long-chain fatty acid CoA ligase, putative Luciferin 4-monooxygenase   550 aa 507 aa 23.5 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 542 aa 18.3 %
Trichomonas vaginalis AMP dependent ligase/synthetase, putative Luciferin 4-monooxygenase   550 aa 476 aa 23.5 %
Schistosoma mansoni neuropeptide receptor ATP-dependent Clp protease proteolytic subunit   197 aa 174 aa 20.1 %
Mycobacterium tuberculosis Probable fatty-acid-AMP ligase FadD24 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 526 aa 21.9 %
Leishmania braziliensis long-chain-fatty-acid-CoA ligase, putative Luciferin 4-monooxygenase   550 aa 504 aa 25.6 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 542 aa 22.1 %
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase FadD15 Luciferin 4-monooxygenase   550 aa 482 aa 24.3 %
Mycobacterium leprae Probable long-chain-fatty-acid-CoA ligase FadD15 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) Luciferin 4-monooxygenase   550 aa 484 aa 23.3 %
Mycobacterium ulcerans peptide synthetase Nrp (peptide synthase) Luciferin 4-monooxygenase   550 aa 535 aa 23.2 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 535 aa 21.7 %
Leishmania braziliensis acetyl-CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 596 aa 21.1 %
Trichomonas vaginalis inositol monophosphatase, putative Inositol monophosphatase 1   277 aa 268 aa 22.4 %
Dictyostelium discoideum 3',5'-bisphosphate nucleotidase Inositol monophosphatase 1   277 aa 230 aa 25.2 %
Cryptosporidium hominis acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 460 aa 26.1 %
Dictyostelium discoideum fatty acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 462 aa 23.8 %
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase Luciferin 4-monooxygenase   550 aa 509 aa 21.8 %
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 Luciferin 4-monooxygenase   550 aa 493 aa 22.1 %
Brugia malayi Inositol monophosphatase family protein Inositol monophosphatase 1   277 aa 238 aa 21.8 %
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit ATP-dependent Clp protease proteolytic subunit   197 aa 183 aa 36.1 %
Echinococcus multilocularis long chain fatty acid coenzyme A ligase 5 Luciferin 4-monooxygenase   550 aa 458 aa 25.5 %
Schistosoma mansoni FAA1 Long-chain-fatty-acid--CoA ligase 1 Luciferin 4-monooxygenase   550 aa 494 aa 26.3 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 538 aa 21.8 %
Brugia malayi Cytochrome P450 family protein cytochrome P450, family 1, subfamily A, polypeptide 2 516 aa 470 aa 26.2 %
Candida albicans one of two closely related genes similar to S. cerevisiae MET22/HAL2 (YOL064C) bisphosphate-3'-nucleotidase, implicated in salt Inositol monophosphatase 1   277 aa 307 aa 22.5 %
Onchocerca volvulus Lysine-specific histone demethylase 1A homolog Luciferin 4-monooxygenase   550 aa 550 aa 22.5 %
Onchocerca volvulus Matrilysin homolog Luciferin 4-monooxygenase   550 aa 466 aa 24.2 %
Trypanosoma cruzi myo-inositol-1 phosphatase, putative Inositol monophosphatase 1   277 aa 284 aa 30.6 %
Treponema pallidum ATP-dependent Clp protease proteolytic subunit ATP-dependent Clp protease proteolytic subunit   197 aa 186 aa 40.3 %
Candida albicans similar to S. cerevisiae ACS2 (YLR153C) acetyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 539 aa 22.1 %
Cryptosporidium parvum acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 460 aa 25.7 %
Echinococcus multilocularis long chain fatty acid transport protein 4 Luciferin 4-monooxygenase   550 aa 476 aa 22.3 %
Trypanosoma brucei inositol-1(or 4)-monophosphatase, putative Inositol monophosphatase 1   277 aa 304 aa 27.3 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 539 aa 19.1 %
Mycobacterium leprae Probable fatty-acid-CoA ligase FadD9 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 461 aa 22.3 %
Echinococcus multilocularis long chain fatty acid coenzyme A ligase 1 Luciferin 4-monooxygenase   550 aa 459 aa 27.0 %
Onchocerca volvulus Luciferin 4-monooxygenase   550 aa 487 aa 23.8 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 522 aa 19.9 %
Trichomonas vaginalis AMP dependent ligase/synthetase, putative Luciferin 4-monooxygenase   550 aa 526 aa 22.4 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 541 aa 21.4 %
Mycobacterium ulcerans acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 601 aa 22.5 %
Dictyostelium discoideum AMP-dependent synthetase and ligase domain-containing protein Luciferin 4-monooxygenase   550 aa 545 aa 24.9 %
Schistosoma japonicum ko:K01897 long-chain fatty-acid-CoA ligase [EC6.2.1.3], putative Luciferin 4-monooxygenase   550 aa 466 aa 27.3 %
Onchocerca volvulus Inositol monophosphatase 1   277 aa 238 aa 22.7 %
Trichomonas vaginalis AMP dependent CoA ligase, putative Luciferin 4-monooxygenase   550 aa 492 aa 23.6 %
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative Luciferin 4-monooxygenase   550 aa 480 aa 21.5 %
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 cytochrome P450, family 2, subfamily C, polypeptide 9 490 aa 441 aa 21.8 %
Cryptosporidium parvum acetyl-coenzyme A synthetase Luciferin 4-monooxygenase   550 aa 545 aa 22.8 %
Cryptosporidium hominis acetyl-CoenzymeA synthetase (acetate--coa ligase) (acyl-activating enzyme) Luciferin 4-monooxygenase   550 aa 549 aa 22.6 %
Schistosoma japonicum ko:K01897 long-chain fatty-acid-CoA ligase [EC6.2.1.3], putative Luciferin 4-monooxygenase   550 aa 541 aa 22.4 %
Cryptosporidium parvum putative long chain fatty acyl CoA synthetase having a signal peptide Luciferin 4-monooxygenase   550 aa 472 aa 24.8 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 507 aa 20.9 %
Candida albicans one of two closely related genes similar to S. cerevisiae MET22/HAL2 (YOL064C) bisphosphate-3'-nucleotidase, implicated in salt Inositol monophosphatase 1   277 aa 300 aa 22.0 %
Trichomonas vaginalis long-chain-fatty-acid CoA ligase, putative Luciferin 4-monooxygenase   550 aa 490 aa 23.3 %
Trichomonas vaginalis AMP dependent ligase/synthetase, putative Luciferin 4-monooxygenase   550 aa 494 aa 24.3 %
Trypanosoma brucei gambiense fatty acyl CoA synthetase 4, putative Luciferin 4-monooxygenase   550 aa 497 aa 23.7 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 539 aa 19.1 %
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD29 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 529 aa 22.3 %
Mycobacterium ulcerans acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 593 aa 22.1 %
Onchocerca volvulus Luciferin 4-monooxygenase   550 aa 502 aa 24.9 %
Dictyostelium discoideum 3',5'-bisphosphate nucleotidase 1 Inositol monophosphatase 1   277 aa 275 aa 22.2 %
Dictyostelium discoideum fatty acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 501 aa 24.4 %
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 505 aa 28.1 %
Plasmodium falciparum ras-related protein Rab-5B RAB9A, member RAS oncogene family 201 aa 165 aa 30.9 %
Mycobacterium leprae PROBABLE FATTY-ACID--CoA LIGASE FADD21 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) Luciferin 4-monooxygenase   550 aa 565 aa 22.8 %
Leishmania donovani long chain fatty Acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 500 aa 23.4 %
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD9 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 480 aa 22.5 %
Loa Loa (eye worm) hypothetical protein Inositol monophosphatase 1   277 aa 298 aa 23.8 %
Leishmania braziliensis long chain fatty Acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 496 aa 22.8 %
Mycobacterium ulcerans non-ribosomal peptide synthetase Luciferin 4-monooxygenase   550 aa 541 aa 22.4 %
Leishmania braziliensis acetyl-CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 603 aa 22.6 %
Plasmodium berghei ATP-dependent Clp protease proteolytic subunit, putative ATP-dependent Clp protease proteolytic subunit   197 aa 180 aa 36.7 %
Dictyostelium discoideum AMP-dependent synthetase and ligase domain-containing protein Luciferin 4-monooxygenase   550 aa 531 aa 19.0 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 499 aa 19.2 %
Neospora caninum Short-chain dehydrogenase/reductase SDR, related Luciferin 4-monooxygenase   550 aa 518 aa 19.1 %
Trichomonas vaginalis AMP dependent CoA ligase, putative Luciferin 4-monooxygenase   550 aa 524 aa 24.0 %
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein Luciferin 4-monooxygenase   550 aa 476 aa 22.5 %
Candida albicans similar to S. cerevisiae ACS2 (YLR153C) acetyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 543 aa 24.5 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 542 aa 18.3 %
Trypanosoma congolense fatty acyl CoA synthetase 2, putative Luciferin 4-monooxygenase   550 aa 500 aa 22.4 %
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD32 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 442 aa 23.5 %
Neospora caninum acetyl-coenzyme a synthetase, putative Luciferin 4-monooxygenase   550 aa 549 aa 20.9 %
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase FadD15 Luciferin 4-monooxygenase   550 aa 484 aa 26.0 %
Trypanosoma congolense inositol-1(or 4)-monophosphatase, putative Inositol monophosphatase 1   277 aa 304 aa 28.9 %
Leishmania mexicana acetyl-CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 559 aa 20.6 %
Candida albicans one of two closely related genes similar to S. cerevisiae MET22/HAL2 (YOL064C) bisphosphate-3'-nucleotidase, implicated in salt Inositol monophosphatase 1   277 aa 306 aa 22.5 %
Trypanosoma brucei gambiense inositol-1(or 4)-monophosphatase, putative Inositol monophosphatase 1   277 aa 309 aa 27.8 %
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase, FadD11 Luciferin 4-monooxygenase   550 aa 492 aa 24.6 %
Toxoplasma gondii type I fatty acid synthase, putative Luciferin 4-monooxygenase   550 aa 514 aa 19.8 %
Trypanosoma cruzi inositol polyphosphate 1-phosphatase, putative Inositol monophosphatase 1   277 aa 291 aa 23.7 %
Dictyostelium discoideum AMP-dependent synthetase and ligase domain-containing protein Luciferin 4-monooxygenase   550 aa 517 aa 24.8 %
Leishmania infantum long chain fatty Acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 500 aa 23.4 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 541 aa 21.4 %
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD28 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 504 aa 22.6 %
Mycobacterium ulcerans putative fatty-acid--CoA ligase Luciferin 4-monooxygenase   550 aa 576 aa 20.8 %
Candida albicans similar to S. cerevisiae ACS2 (YLR153C) acetyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 543 aa 24.5 %
Babesia bovis fatty acyl-CoA synthetase family protein Luciferin 4-monooxygenase   550 aa 461 aa 23.4 %
Onchocerca volvulus Putative 28S ribosomal protein S10, mitochondrial Inositol monophosphatase 1   277 aa 271 aa 46.1 %
Babesia bovis ATP-dependent Clp protease proteolytic subunit, putative ATP-dependent Clp protease proteolytic subunit   197 aa 188 aa 41.5 %
Babesia bovis ATP-dependent Clp protease proteolytic subunit, putative ATP-dependent Clp protease proteolytic subunit   197 aa 188 aa 41.5 %
Onchocerca volvulus Putative trans-2-enoyl-CoA reductase 1, mitochondrial Inositol monophosphatase 1   277 aa 278 aa 23.0 %
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD26 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 560 aa 21.4 %
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative ATP-dependent Clp protease proteolytic subunit   197 aa 189 aa 35.5 %
Brugia malayi AMP-binding enzyme family protein Luciferin 4-monooxygenase   550 aa 497 aa 24.7 %
Trichomonas vaginalis diphosphonucleoside phosphohydrolase, putative Inositol monophosphatase 1   277 aa 263 aa 21.7 %
Loa Loa (eye worm) pigment dispersing factor receptor c glucagon-like peptide 1 receptor 463 aa 388 aa 25.8 %
Babesia bovis long-chain acyl-CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 445 aa 21.8 %
Trichomonas vaginalis antibiotic synthetase, putative Luciferin 4-monooxygenase   550 aa 581 aa 21.2 %
Trichomonas vaginalis myo inositol monophosphatase, putative Inositol monophosphatase 1   277 aa 276 aa 21.4 %
Leishmania mexicana long chain fatty Acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 483 aa 23.8 %
Trichomonas vaginalis AMP dependent ligase/synthetase, putative Luciferin 4-monooxygenase   550 aa 554 aa 22.9 %
Mycobacterium ulcerans acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 497 aa 19.3 %
Mycobacterium tuberculosis Probable fatty-acid-AMP ligase FadD25 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 475 aa 21.1 %
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) Luciferin 4-monooxygenase   550 aa 509 aa 22.6 %
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative Luciferin 4-monooxygenase   550 aa 476 aa 20.8 %
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative Luciferin 4-monooxygenase   550 aa 494 aa 23.9 %
Leishmania major cytochrome p450-like protein cytochrome P450, family 2, subfamily C, polypeptide 19 490 aa 411 aa 23.1 %
Echinococcus multilocularis long chain fatty acid coenzyme A ligase 1 Luciferin 4-monooxygenase   550 aa 443 aa 26.4 %
Candida albicans similar to S. cerevisiae ACS2 (YLR153C) acetyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 539 aa 22.1 %
Mycobacterium tuberculosis Probable acyl-CoA ligase FadD31 (acyl-CoA synthetase) (acyl-CoA synthase) Luciferin 4-monooxygenase   550 aa 592 aa 20.4 %
Onchocerca volvulus Putative V-type proton ATPase subunit F ATP-dependent Clp protease proteolytic subunit   197 aa 194 aa 54.1 %
Candida albicans similar to S. cerevisiae FAA4 (YMR246W) long-chain fatty acid--CoA synthetase Luciferin 4-monooxygenase   550 aa 478 aa 23.4 %
Echinococcus granulosus long chain fatty acid coenzyme A ligase 5 Luciferin 4-monooxygenase   550 aa 458 aa 25.8 %
Trichomonas vaginalis AMP dependent ligase/synthetase, putative Luciferin 4-monooxygenase   550 aa 554 aa 24.4 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 463 aa 23.5 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 535 aa 22.6 %
Trichomonas vaginalis AMP dependent ligase, putative Luciferin 4-monooxygenase   550 aa 445 aa 26.1 %
Echinococcus granulosus long chain fatty acid transport protein 4 Luciferin 4-monooxygenase   550 aa 476 aa 22.3 %
Trypanosoma cruzi fatty acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 480 aa 25.2 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 576 aa 19.8 %
Entamoeba histolytica 3(2),5-bisphosphate nucleotidase, putative Inositol monophosphatase 1   277 aa 263 aa 24.0 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 478 aa 21.1 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 541 aa 21.6 %
Mycobacterium ulcerans acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 582 aa 22.3 %
Mycobacterium leprae ATP-dependent Clp protease proteolytic subunit 1 ATP-dependent Clp protease proteolytic subunit   197 aa 172 aa 57.0 %
Trichomonas vaginalis antibiotic synthetase, putative Luciferin 4-monooxygenase   550 aa 577 aa 22.2 %
Trichomonas vaginalis long-chain-fatty-acid CoA ligase, putative Luciferin 4-monooxygenase   550 aa 466 aa 21.7 %
Trypanosoma cruzi fatty acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 482 aa 24.7 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 558 aa 20.4 %
Mycobacterium ulcerans fatty-acid-CoA ligase FadD9 Luciferin 4-monooxygenase   550 aa 463 aa 21.8 %
Candida albicans similar to S. cerevisiae FAT1 (YBR041W) fatty acid transporter and very long-chain fatty acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 496 aa 24.2 %
Mycobacterium ulcerans acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 530 aa 23.8 %
Candida albicans similar to S. cerevisiae FAT1 (YBR041W) fatty acid transporter and very long-chain fatty acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 496 aa 24.2 %
Mycobacterium tuberculosis Probable fatty-acid-AMP ligase FadD23 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 542 aa 23.8 %
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD29 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 617 aa 22.2 %
Leishmania major long chain fatty Acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 482 aa 23.2 %
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD34 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 537 aa 20.9 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 538 aa 21.8 %
Brugia malayi Hypothetical 65.5 kDa Trp-Asp repeats containing protein F02E8.5 inchromosome X geminin, DNA replication inhibitor 209 aa 176 aa 27.8 %
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD32 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase). Also shown to have acyl-ACP ligase activity. Luciferin 4-monooxygenase   550 aa 487 aa 22.4 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 522 aa 19.9 %
Brugia malayi AMP-binding enzyme family protein Luciferin 4-monooxygenase   550 aa 544 aa 21.5 %
Chlamydia trachomatis hypothetical protein ATP-dependent Clp protease proteolytic subunit   197 aa 171 aa 22.8 %
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtE Luciferin 4-monooxygenase   550 aa 502 aa 22.5 %
Mycobacterium tuberculosis Probable fatty-acid-AMP ligase FadD21 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 586 aa 24.4 %
Trichomonas vaginalis AMP dependent CoA ligase, putative Luciferin 4-monooxygenase   550 aa 527 aa 25.0 %
Trypanosoma brucei gambiense fatty acyl CoA synthetase 3 Luciferin 4-monooxygenase   550 aa 491 aa 23.6 %
Entamoeba histolytica acyl-CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 446 aa 22.0 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 542 aa 22.1 %
Schistosoma japonicum ko:K08745 solute carrier family 27 (fatty acid transporter), member 1, putative Luciferin 4-monooxygenase   550 aa 501 aa 24.6 %
Trypanosoma brucei fatty acyl CoA synthetase 3 Luciferin 4-monooxygenase   550 aa 491 aa 23.6 %
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase Luciferin 4-monooxygenase   550 aa 536 aa 24.4 %
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD28 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 484 aa 20.5 %
Mycobacterium ulcerans fatty-acid-CoA ligase FadD11 Luciferin 4-monooxygenase   550 aa 498 aa 23.5 %
Schistosoma japonicum ko:K01082 3'(2'), 5'-bisphosphate nucleotidase [EC3.1.3.7], putative Inositol monophosphatase 1   277 aa 275 aa 21.5 %
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtF Luciferin 4-monooxygenase   550 aa 558 aa 20.1 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 541 aa 21.6 %
Plasmodium yoelii Clp protease ATP-dependent Clp protease proteolytic subunit   197 aa 183 aa 36.6 %
Toxoplasma gondii propionate-CoA ligase Luciferin 4-monooxygenase   550 aa 550 aa 21.1 %
Schistosoma mansoni pap-inositol-14-phosphatase Inositol monophosphatase 1   277 aa 279 aa 22.9 %
Echinococcus granulosus long chain fatty acid coenzyme A ligase 1 Luciferin 4-monooxygenase   550 aa 452 aa 26.1 %
Mycobacterium leprae FATTY-ACID-CoA LIGASE FADD26 (FATTY-ACID-COA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) Luciferin 4-monooxygenase   550 aa 533 aa 22.7 %
Trichomonas vaginalis inositol monophosphatase, putative Inositol monophosphatase 1   277 aa 258 aa 21.7 %
Plasmodium knowlesi ATP-dependent Clp protease proteolytic subunit, putative ATP-dependent Clp protease proteolytic subunit   197 aa 189 aa 36.0 %
Trypanosoma cruzi fatty acyl CoA synthetase 2, putative Luciferin 4-monooxygenase   550 aa 495 aa 22.6 %
Loa Loa (eye worm) AMP-binding enzyme family protein Luciferin 4-monooxygenase   550 aa 489 aa 23.3 %
Dictyostelium discoideum AMP-dependent synthetase and ligase domain-containing protein Luciferin 4-monooxygenase   550 aa 550 aa 20.9 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus multilocularis cathepsin b 0.0608 0.6161 0.6161
Mycobacterium ulcerans beta-lactamase 0.0043 0.0322 0.2079
Onchocerca volvulus 0.0058 0.0475 0.203
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0045 0.0334 0.1642
Onchocerca volvulus 0.0238 0.2339 1
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0094 0.0849 1
Toxoplasma gondii cathepsin B 0.0206 0.2007 1
Loa Loa (eye worm) hypothetical protein 0.0023 0.0112 0.0182
Loa Loa (eye worm) hypothetical protein 0.0029 0.0169 0.0274
Loa Loa (eye worm) hypothetical protein 0.0027 0.0147 0.0239
Entamoeba histolytica cysteine protease, putative 0.0027 0.0147 0.1326
Echinococcus multilocularis cpg binding protein 0.0037 0.0252 0.0252
Schistosoma mansoni cathepsin F (C01 family) 0.0042 0.0306 0.0361
Leishmania major hypothetical protein, conserved 0.003 0.0188 0.091
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0022 0.0099 0.0466
Echinococcus multilocularis Chromobox protein 3 0.0014 0.0015 0.0015
Echinococcus multilocularis neuropeptides capa receptor 0.0023 0.0112 0.0112
Brugia malayi nuclear hormone receptor 0.0023 0.0114 0.0184
Echinococcus granulosus Chromobox protein 3 0.0014 0.0015 0.0018
Trichomonas vaginalis PIKK family atypical protein kinase 0.0022 0.0099 0.0421
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0218 0.0932
Trichomonas vaginalis PIKK family atypical protein kinase 0.0022 0.0099 0.0421
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0042 0.0306 0.1309
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0023 0.0112 0.0132
Trichomonas vaginalis PIKK family atypical protein kinase 0.0022 0.0099 0.0421
Echinococcus granulosus sterol regulatory element binding protein 0.0051 0.04 0.0472
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0042 0.0306 0.0306
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0023 0.0112 0.0132
Mycobacterium tuberculosis Conserved protein 0.0043 0.0322 0.1157
Loa Loa (eye worm) hypothetical protein 0.0031 0.019 0.0309
Entamoeba histolytica cysteine proteinase, putative 0.0042 0.0306 0.2756
Brugia malayi ORL1-like opioid receptor 0.0023 0.0112 0.0182
Giardia lamblia Cathepsin L precursor 0.0027 0.0147 0.0256
Schistosoma mansoni neuropeptide receptor 0.0023 0.0112 0.0132
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0042 0.0306 0.1503
Loa Loa (eye worm) hypothetical protein 0.0286 0.2826 0.4587
Brugia malayi cathepsin Z-like cysteine proteinase 0.0027 0.0147 0.0239
Loa Loa (eye worm) neuropeptide F receptor 0.0023 0.0112 0.0182
Loa Loa (eye worm) hypothetical protein 0.0062 0.0519 0.0843
Brugia malayi cathepsin F-like cysteine proteinase 0.0015 0.0032 0.0051
Trypanosoma cruzi target of rapamycin kinase 3 0.0022 0.0099 0.016
Loa Loa (eye worm) hypothetical protein 0.0023 0.0112 0.0182
Loa Loa (eye worm) hypothetical protein 0.0023 0.0112 0.0182
Brugia malayi GnHR receptor homolog 0.0023 0.0112 0.0182
Echinococcus granulosus biogenic amine 5HT receptor 0.0023 0.0112 0.0132
Plasmodium falciparum serine repeat antigen 1 0.0027 0.0147 0.1585
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0043 0.0322 0.1157
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0206 0.2007 0.8581
Onchocerca volvulus 0.0023 0.0112 0.0477
Trichomonas vaginalis PIKK family atypical protein kinase 0.0022 0.0099 0.0421
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0027 0.0147 0.063
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0038 0.0267 0.0267
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) 0.0062 0.0513 0.1852
Schistosoma mansoni hypothetical protein 0.0014 0.0015 0.0018
Onchocerca volvulus 0.0043 0.0322 0.1376
Loa Loa (eye worm) hypothetical protein 0.0029 0.0169 0.0274
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0042 0.0306 0.0497
Mycobacterium tuberculosis Class a beta-lactamase BlaC 0.016 0.153 0.5565
Echinococcus multilocularis neuropeptide receptor A26 0.0023 0.0112 0.0112
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0027 0.0147 0.0256
Loa Loa (eye worm) hypothetical protein 0.0023 0.0112 0.0182
Trichomonas vaginalis PIKK family atypical protein kinase 0.0022 0.0099 0.0421
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0027 0.0147 0.063
Loa Loa (eye worm) latrophilin receptor protein 2 0.0038 0.0267 0.0433
Onchocerca volvulus 0.0023 0.0112 0.0477
Echinococcus granulosus 7TM GPCR rhodopsin 0.0023 0.0112 0.0132
Loa Loa (eye worm) hypothetical protein 0.0014 0.0015 0.0025
Loa Loa (eye worm) hypothetical protein 0.0023 0.0112 0.0182
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0014 0.0015 0.0018
Brugia malayi follicle stimulating hormone receptor 0.0023 0.0112 0.0182
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0023 0.0112 0.0132
Plasmodium falciparum serine repeat antigen 8 0.0027 0.0147 0.1585
Echinococcus granulosus cathepsin L 0.0027 0.0147 0.0174
Trichomonas vaginalis PIKK family atypical protein kinase 0.0022 0.0099 0.0421
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0045 0.0334 0.1642
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0045 0.0334 0.0542
Leishmania major hypothetical protein, conserved 0.0043 0.0322 0.1584
Loa Loa (eye worm) hypothetical protein 0.0021 0.0094 0.0153
Trypanosoma cruzi hypothetical protein, conserved 0.0043 0.0322 0.0523
Echinococcus granulosus expressed conserved protein 0.0112 0.1028 0.121
Plasmodium vivax hypothetical protein, conserved 0.0043 0.0322 0.3683
Echinococcus granulosus fmrfamide receptor 0.0023 0.0112 0.0132
Brugia malayi hypothetical protein 0.0023 0.0112 0.0182
Loa Loa (eye worm) beta-lactamase 0.0043 0.0322 0.0523
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0015 0.0062
Echinococcus multilocularis fmrfamide receptor 0.0023 0.0112 0.0112
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0022 0.0099 0.0099
Trichomonas vaginalis Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase 0.0027 0.0147 0.063
Echinococcus granulosus rhodopsin orphan GPCR 0.0023 0.0112 0.0132
Loa Loa (eye worm) melatonin receptor type 1A 0.0023 0.0112 0.0182
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.019 0.0224
Schistosoma mansoni biogenic amine receptor 0.0023 0.0112 0.0132
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0013 0.0005 0.0008
Loa Loa (eye worm) hypothetical protein 0.0023 0.0112 0.0182
Trichomonas vaginalis set domain proteins, putative 0.0238 0.2339 1
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0042 0.0306 0.0497
Loa Loa (eye worm) hypothetical protein 0.0023 0.0112 0.0182
Giardia lamblia Cathepsin B precursor 0.0027 0.0147 0.0256
Mycobacterium ulcerans acyl-CoA synthetase 0.0029 0.0169 0.1072
Trypanosoma cruzi cysteine peptidase, putative 0.0042 0.0306 0.0497
Brugia malayi hypothetical protein 0.0023 0.0112 0.0182
Loa Loa (eye worm) hypothetical protein 0.0023 0.0112 0.0182
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0014 0.0015 0.0064
Schistosoma mansoni hypothetical protein 0.0038 0.0267 0.0314
Brugia malayi Cathepsin L-like precursor 0.0042 0.0306 0.0497
Trichomonas vaginalis PIKK family atypical protein kinase 0.0022 0.0099 0.0421
Echinococcus multilocularis rhodopsin orphan GPCR 0.0023 0.0112 0.0112
Plasmodium falciparum ataxin-2 like protein, putative 0.003 0.0188 0.2066
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0119 0.1102 0.9921
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0023 0.0112 0.0132
Trypanosoma cruzi cysteine proteinase, putative 0.0042 0.0306 0.0497
Loa Loa (eye worm) hypothetical protein 0.0014 0.0015 0.0024
Schistosoma mansoni inositol monophosphatase 0.0045 0.0334 0.0393
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0023 0.0114 0.0184
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0015 0.0064
Loa Loa (eye worm) cytochrome P450 0.0013 0.0005 0.0009
Echinococcus granulosus g-protein coupled receptor 0.0023 0.0112 0.0132
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0023 0.0112 0.0132
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0022 0.0099 0.0116
Trichomonas vaginalis PIKK family atypical protein kinase 0.0022 0.0099 0.0421
Brugia malayi cathepsin L precursor 0.0027 0.0147 0.0239
Mycobacterium ulcerans esterase/lipase LipP 0.0043 0.0322 0.2079
Toxoplasma gondii ABC1 family protein 0.0043 0.0322 0.1584
Echinococcus granulosus cytochrome P450 2K1 0.0013 0.0005 0.0006
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0033 0.0209 0.2326
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0023 0.0112 0.0112
Onchocerca volvulus 0.0043 0.0322 0.1376
Giardia lamblia Cathepsin B precursor 0.0027 0.0147 0.0256
Schistosoma mansoni neuropeptide F-like receptor 0.0023 0.0112 0.0132
Schistosoma mansoni alpha-1 adrenergic receptor 0.0023 0.0112 0.0132
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0022 0.0096 0.0412
Entamoeba histolytica hypothetical protein 0.0027 0.0147 0.1326
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0023 0.0112 0.0132
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0042 0.0306 0.1503
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0023 0.0114 0.0114
Loa Loa (eye worm) hypothetical protein 0.0023 0.0112 0.0182
Entamoeba histolytica cysteine proteinase, putative 0.0042 0.0306 0.2756
Trichomonas vaginalis PIKK family atypical protein kinase 0.0022 0.0099 0.0421
Onchocerca volvulus 0.0043 0.0322 0.1376
Echinococcus multilocularis g protein coupled receptor 0.0023 0.0112 0.0112
Schistosoma mansoni adenoreceptor 0.0023 0.0112 0.0132
Leishmania major cathepsin L-like protease 0.0042 0.0306 0.1503
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0038 0.0267 0.0433
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0022 0.0099 0.016
Brugia malayi HSF-type DNA-binding domain containing protein 0.012 0.1111 0.1804
Entamoeba histolytica acyl-CoA synthetase, putative 0.0029 0.0169 0.1519
Loa Loa (eye worm) hypothetical protein 0.0023 0.0112 0.0182
Trichomonas vaginalis inositol monophosphatase, putative 0.0045 0.0334 0.1428
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0043 0.0322 0.1157
Brugia malayi cathepsin F-like cysteine proteinase 0.0027 0.0147 0.0239
Onchocerca volvulus 0.0023 0.0112 0.0477
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0027 0.0147 0.063
Plasmodium falciparum dipeptidyl aminopeptidase 3 0.0027 0.0147 0.1585
Echinococcus multilocularis rhodopsin orphan GPCR 0.0023 0.0112 0.0112
Loa Loa (eye worm) hypothetical protein 0.0026 0.014 0.0227
Loa Loa (eye worm) hypothetical protein 0.0023 0.0112 0.0182
Onchocerca volvulus 0.0027 0.0147 0.0628
Loa Loa (eye worm) hypothetical protein 0.0023 0.0112 0.0182
Trypanosoma cruzi cysteine peptidase, putative 0.0015 0.0032 0.0051
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0027 0.0147 0.0256
Loa Loa (eye worm) helicase 0.0014 0.0015 0.0025
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0022 0.0099 0.0161
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0022 0.0099 0.0116
Echinococcus granulosus peptidase Clp S14 family 0.0062 0.0513 0.0604
Echinococcus multilocularis serotonin receptor 0.0023 0.0112 0.0112
Entamoeba histolytica acyl-coA synthetase, putative 0.0029 0.0169 0.1519
Brugia malayi Cathepsin L-like precursor 0.0027 0.0147 0.0239
Echinococcus granulosus FTZ F1 alpha 0.0023 0.0114 0.0134
Leishmania major phosphatidylinositol 3-kinase, putative 0.0022 0.0099 0.0466
Brugia malayi chromobox protein homolog 3 0.0047 0.0361 0.0585
Schistosoma mansoni hypothetical protein 0.0205 0.1989 0.2343
Schistosoma mansoni hypothetical protein 0.0023 0.0112 0.0132
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0027 0.0147 0.0239
Schistosoma mansoni hypothetical protein 0.0049 0.0381 0.0449
Trichomonas vaginalis chromobox protein, putative 0.0014 0.0015 0.0064
Entamoeba histolytica cysteine protease, putative 0.0027 0.0147 0.1326
Schistosoma mansoni hypothetical protein 0.0023 0.0112 0.0132
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0045 0.0334 0.1428
Onchocerca volvulus Protein ultraspiracle homolog 0.0023 0.0114 0.0483
Echinococcus multilocularis neuropeptide Y receptor 0.0023 0.0112 0.0112
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0027 0.0147 0.063
Echinococcus multilocularis cathepsin L cysteine protease 0.0042 0.0306 0.0306
Plasmodium falciparum serine repeat antigen 5 0.0027 0.0147 0.1585
Onchocerca volvulus Cathepsin L homolog 0.0042 0.0306 0.1307
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0023 0.0112 0.0477
Entamoeba histolytica cysteine proteinase 2 0.0042 0.0306 0.2756
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0023 0.0112 0.0132
Trichomonas vaginalis D-aminoacylase, putative 0.0043 0.0322 0.1378
Onchocerca volvulus Bile acid receptor homolog 0.0023 0.0114 0.0483
Echinococcus multilocularis rhodopsin orphan GPCR 0.0023 0.0112 0.0112
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0094 0.0849 0.4216
Echinococcus granulosus rhodopsin orphan GPCR 0.0023 0.0112 0.0132
Brugia malayi hypothetical protein 0.003 0.0188 0.0305
Echinococcus multilocularis ATP dependent Clp protease proteolytic subunit 0.0094 0.0849 0.0849
Schistosoma mansoni hypothetical protein 0.0023 0.0112 0.0132
Trypanosoma cruzi PAB1-binding protein , putative 0.003 0.0188 0.0304
Onchocerca volvulus Cathepsin L homolog 0.0042 0.0306 0.1307
Echinococcus granulosus serotonin receptor 0.0023 0.0112 0.0132
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0015 0.0032 0.0051
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.0027 0.0147 0.1585
Schistosoma mansoni chromobox protein 0.0014 0.0015 0.0018
Leishmania major 4-coumarate:coa ligase-like protein 0.0029 0.0169 0.0817
Plasmodium falciparum serine repeat antigen 6 0.0027 0.0147 0.1585
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0042 0.0306 0.1309
Schistosoma mansoni chromobox protein 0.0084 0.0743 0.0875
Echinococcus multilocularis peptidase Clp (S14 family) 0.0062 0.0513 0.0513
Echinococcus multilocularis cysteine protease 0.0042 0.0306 0.0306
Loa Loa (eye worm) hypothetical protein 0.0027 0.0147 0.0239
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0608 0.6161 0.7255
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0023 0.0112 0.0182
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0608 0.6161 0.7255
Echinococcus granulosus histone lysine methyltransferase setb 0.0031 0.019 0.0224
Entamoeba histolytica hypothetical protein 0.0014 0.0015 0.0135
Schistosoma mansoni cytochrome P450 0.0013 0.0005 0.0006
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0022 0.0096 0.0412
Mycobacterium tuberculosis Probable conserved lipoprotein LpqF 0.0077 0.0668 0.2419
Onchocerca volvulus 0.0023 0.0112 0.0477
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0608 0.6161 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0022 0.0099 0.0421
Leishmania major cathepsin L-like protease 0.0042 0.0306 0.1503
Echinococcus granulosus chromobox protein 2 0.0014 0.0015 0.0018
Loa Loa (eye worm) hypothetical protein 0.0014 0.0015 0.0025
Schistosoma mansoni inositol monophosphatase 0.0045 0.0334 0.0393
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0042 0.0306 0.0306
Loa Loa (eye worm) hypothetical protein 0.0023 0.0114 0.0184
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0023 0.0112 0.0112
Trypanosoma cruzi major cysteine proteinase, putative 0.0027 0.0147 0.0239
Schistosoma mansoni hypothetical protein 0.0205 0.1989 0.2343
Wolbachia endosymbiont of Brugia malayi ATP-dependent Clp protease proteolytic subunit 0.0094 0.0849 1
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0013 0.0005 0.0008
Onchocerca volvulus 0.0042 0.0306 0.1307
Brugia malayi putative neuropeptide receptor NPR1 0.0023 0.0112 0.0182
Echinococcus granulosus GPCR family 2 0.0038 0.0267 0.0314
Onchocerca volvulus 0.0042 0.0306 0.1307
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0023 0.0114 0.0134
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0045 0.0334 0.2156
Schistosoma mansoni neuropeptide receptor 0.0023 0.0112 0.0132
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0031 0.019 0.019
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0042 0.0306 0.1309
Onchocerca volvulus 0.0023 0.0112 0.0477
Loa Loa (eye worm) hypothetical protein 0.0023 0.0112 0.0182
Echinococcus multilocularis G-protein coupled receptor, putative 0.0023 0.0112 0.0112
Loa Loa (eye worm) hypothetical protein 0.0023 0.0112 0.0182
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0027 0.0147 0.063
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0147 0.063
Loa Loa (eye worm) hypothetical protein 0.0014 0.0015 0.0025
Loa Loa (eye worm) hypothetical protein 0.0023 0.0112 0.0182
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0023 0.0112 0.0182
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0029 0.0169 0.0597
Entamoeba histolytica hypothetical protein 0.0014 0.0015 0.0135
Mycobacterium ulcerans hypothetical protein 0.0043 0.0322 0.2079
Schistosoma mansoni amine GPCR 0.0023 0.0112 0.0132
Brugia malayi beta-lactamase 0.0043 0.0322 0.0523
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0023 0.0112 0.0182
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0023 0.0112 0.0112
Trichomonas vaginalis hypothetical protein 0.0014 0.0015 0.0064
Entamoeba histolytica hypothetical protein 0.0014 0.0015 0.0135
Trypanosoma brucei beta lactamase 0.0077 0.0668 0.3312
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0022 0.0099 0.0116
Schistosoma mansoni opsin-like receptor 0.0023 0.0112 0.0132
Trichomonas vaginalis PIKK family atypical protein kinase 0.0022 0.0099 0.0421
Trypanosoma cruzi cytochrome P450, putative 0.0013 0.0005 0.0008
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0023 0.0112 0.0112
Echinococcus granulosus allatostatin A receptor 0.0023 0.0112 0.0132
Brugia malayi RE15519p 0.0023 0.0112 0.0182
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0023 0.0114 0.0184
Echinococcus granulosus serine protein kinase ATM 0.003 0.0183 0.0216
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0023 0.0112 0.0182
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0027 0.0147 0.1585
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.019 0.0224
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0023 0.0114 0.0114
Plasmodium vivax serine-repeat antigen 3 (SERA) 0.0027 0.0147 0.1585
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0022 0.0096 0.0412
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0026 0.014 0.0226
Echinococcus granulosus tachykinin peptides receptor 99D 0.0023 0.0112 0.0132
Toxoplasma gondii hypothetical protein 0.0033 0.0209 0.1019
Echinococcus multilocularis cathepsin L 0.0027 0.0147 0.0147
Brugia malayi putative neuropeptide receptor 0.0023 0.0112 0.0182
Schistosoma mansoni chromobox protein 0.0084 0.0743 0.0875
Brugia malayi latrophilin 2 splice variant baaae 0.0082 0.0724 0.1175
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0042 0.0306 0.1309
Loa Loa (eye worm) hypothetical protein 0.0043 0.0322 0.0523
Loa Loa (eye worm) hypothetical protein 0.0021 0.0094 0.0153
Echinococcus multilocularis rhodopsin orphan GPCR 0.0023 0.0112 0.0112
Loa Loa (eye worm) hypothetical protein 0.0023 0.0112 0.0182
Brugia malayi Melatonin receptor type 1A 0.0023 0.0112 0.0182
Giardia lamblia Cathepsin L-like protease 0.0027 0.0147 0.0256
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.0206 0.2007 1
Schistosoma mansoni hypothetical protein 0.0038 0.0267 0.0314
Echinococcus multilocularis cysteine protease 0.0042 0.0306 0.0306
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0029 0.0171 0.0202
Loa Loa (eye worm) hypothetical protein 0.0023 0.0114 0.0184
Brugia malayi Serotonin receptor 0.0023 0.0112 0.0182
Trichomonas vaginalis PIKK family atypical protein kinase 0.0022 0.0099 0.0421
Schistosoma mansoni cpg binding protein 0.0037 0.0252 0.0297
Echinococcus multilocularis 0.0013 0.0005 0.0005
Brugia malayi hypothetical protein 0.0023 0.0112 0.0182
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0027 0.0147 0.063
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0094 0.0849 0.5536
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0218 0.0932
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0014 0.0015 0.0049
Mycobacterium ulcerans lipase LipD 0.0043 0.0322 0.2079
Brugia malayi Valyl-tRNA synthetase 0.0014 0.0015 0.0025
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0014 0.0014 0.0014
Echinococcus multilocularis neuropeptide FF receptor 2 0.0023 0.0112 0.0112
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0047 0.0361 0.1539
Trichomonas vaginalis PIKK family atypical protein kinase 0.0022 0.0099 0.0421
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0027 0.0147 0.0174
Echinococcus granulosus g protein coupled receptor 0.0023 0.0112 0.0132
Loa Loa (eye worm) hypothetical protein 0.0043 0.0322 0.0523
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0027 0.0147 0.063
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0029 0.0169 0.1072
Plasmodium vivax serine-repeat antigen 4 (SERA) 0.0027 0.0147 0.1585
Loa Loa (eye worm) hypothetical protein 0.0023 0.0112 0.0182
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0022 0.0096 0.0412
Schistosoma mansoni biogenic amine receptor 0.0023 0.0112 0.0132
Brugia malayi Calcitonin receptor-like protein seb-1 0.012 0.1118 0.1815
Giardia lamblia Cathepsin L precursor 0.0027 0.0147 0.0256
Schistosoma mansoni hypothetical protein 0.0049 0.0381 0.0449
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0014 0.0015 0.0135
Entamoeba histolytica cysteine protease, putative 0.0042 0.0306 0.2756
Mycobacterium ulcerans lipoprotein LpqF 0.0077 0.0668 0.4348
Onchocerca volvulus 0.0023 0.0112 0.0477
Trichomonas vaginalis PIKK family atypical protein kinase 0.0022 0.0099 0.0421
Schistosoma mansoni myosin xvIII 0.0023 0.0112 0.0132
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0075 0.0645 0.076
Loa Loa (eye worm) hypothetical protein 0.0023 0.0112 0.0182
Echinococcus granulosus dro:myosuppressin receptor 0.0023 0.0112 0.0132
Onchocerca volvulus 0.0042 0.0306 0.1307
Schistosoma mansoni growth hormone secretagogue receptor 0.0023 0.0112 0.0132
Echinococcus granulosus neuropeptide receptor 0.0023 0.0112 0.0132
Echinococcus multilocularis microtubule associated protein 2 0.0833 0.8491 0.8491
Echinococcus multilocularis geminin 0.0205 0.1989 0.1989
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0023 0.0114 0.0184
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0022 0.0099 0.0466
Echinococcus granulosus cathepsin L cysteine proteinase 0.0042 0.0306 0.0361
Plasmodium falciparum serine repeat antigen 4 0.0027 0.0147 0.1585
Brugia malayi hypothetical protein 0.0286 0.2826 0.4587
Echinococcus multilocularis Niemann Pick C1 protein 0.017 0.163 0.163
Loa Loa (eye worm) hypothetical protein 0.0015 0.0032 0.0051
Brugia malayi AMP-binding enzyme family protein 0.0029 0.0169 0.0274
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0015 0.0064
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.0608 0.6161 0.7255
Mycobacterium tuberculosis Probable lipase LipD 0.0043 0.0322 0.1157
Loa Loa (eye worm) CXXC zinc finger family protein 0.0035 0.0231 0.0376
Mycobacterium tuberculosis Conserved protein 0.0043 0.0322 0.1157
Echinococcus multilocularis protein patched 0.0051 0.04 0.04
Plasmodium vivax unspecified product 0.0027 0.0147 0.1585
Echinococcus multilocularis allatostatin A receptor 0.0023 0.0112 0.0112
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0029 0.0169 0.1072
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0023 0.0112 0.0182
Echinococcus granulosus cathepsin b 0.0608 0.6161 0.7255
Trichomonas vaginalis PIKK family atypical protein kinase 0.0022 0.0099 0.0421
Brugia malayi cahepsin L-like non-peptiedase homolog 0.0027 0.0147 0.0239
Trichomonas vaginalis esterase, putative 0.0043 0.0322 0.1378
Leishmania major cathepsin L-like protease 0.0042 0.0306 0.1503
Onchocerca volvulus Neuropeptide F receptor homolog 0.0023 0.0112 0.0477
Echinococcus multilocularis thyroid hormone receptor alpha 0.0023 0.0114 0.0114
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0023 0.0112 0.0132
Echinococcus granulosus microtubule associated protein 2 0.0833 0.8491 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0042 0.0306 0.1309
Brugia malayi Cathepsin L-like precursor 0.0015 0.0032 0.0051
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0029 0.0169 0.1072
Plasmodium vivax serine-repeat antigen 2 (SERA) 0.0027 0.0147 0.1585
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0015 0.0032 0.0051
Giardia lamblia Cysteine protease 0.0027 0.0147 0.0256
Schistosoma mansoni hypothetical protein 0.0049 0.0381 0.0449
Echinococcus granulosus rhodopsin orphan GPCR 0.0023 0.0112 0.0132
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0038 0.0267 0.0267
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0023 0.0112 0.0132
Schistosoma mansoni steroid hormone receptor ad4bp 0.0023 0.0114 0.0134
Echinococcus granulosus orexin receptor type 2 0.0023 0.0112 0.0132
Giardia lamblia Cathepsin B precursor 0.0027 0.0147 0.0256
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0023 0.0112 0.0132
Schistosoma mansoni thyroid hormone receptor 0.0023 0.0114 0.0134
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0015 0.0064
Entamoeba histolytica cysteine protease, putative 0.0027 0.0147 0.1326
Plasmodium vivax unspecified product 0.0015 0.0032 0.0197
Plasmodium falciparum serine repeat antigen 2 0.0027 0.0147 0.1585
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0051 0.04 0.065
Loa Loa (eye worm) hypothetical protein 0.0023 0.0112 0.0182
Entamoeba histolytica cysteine protease, putative 0.0027 0.0147 0.1326
Brugia malayi Protein cec-1. 0.0014 0.0015 0.0025
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0042 0.0306 0.1309
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0027 0.0147 0.0239
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0027 0.0147 0.1326
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0042 0.0306 0.1309
Trypanosoma cruzi major cysteine proteinase, putative 0.0027 0.0147 0.0239
Loa Loa (eye worm) cathepsin B 0.0206 0.2007 0.3258
Trichomonas vaginalis PIKK family atypical protein kinase 0.0022 0.0099 0.0421
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.002 0.0082 0.0279
Brugia malayi ecdysteroid receptor 0.0023 0.0114 0.0184
Entamoeba histolytica cysteine protease, putative 0.0027 0.0147 0.1326
Entamoeba histolytica cysteine protease, putative 0.0042 0.0306 0.2756
Loa Loa (eye worm) hypothetical protein 0.0023 0.0112 0.0182
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0042 0.0306 0.1503
Loa Loa (eye worm) hypothetical protein 0.0023 0.0112 0.0182
Schistosoma mansoni coup transcription factor 0.0023 0.0114 0.0134
Trichomonas vaginalis PIKK family atypical protein kinase 0.0022 0.0099 0.0421
Leishmania major cathepsin L-like protease 0.0042 0.0306 0.1503
Schistosoma mansoni cathepsin F (C01 family) 0.0027 0.0147 0.0174
Mycobacterium leprae ATP-dependent Clp protease proteolytic subunit 1 0.0033 0.0209 0.2416
Trypanosoma cruzi cysteine peptidase, putative 0.0042 0.0306 0.0497
Trypanosoma cruzi cysteine peptidase, putative 0.0042 0.0306 0.0497
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0023 0.0112 0.0132
Schistosoma mansoni microtubule-associated protein tau 0.0833 0.8491 1
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0023 0.0112 0.0182
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0027 0.0147 0.0256
Loa Loa (eye worm) hypothetical protein 0.0023 0.0114 0.0184
Loa Loa (eye worm) hypothetical protein 0.0023 0.0112 0.0182
Plasmodium falciparum serine repeat antigen 9 0.0027 0.0147 0.1585
Echinococcus granulosus dnaJ subfamily B 0.0494 0.4981 0.5866
Loa Loa (eye worm) hypothetical protein 0.0047 0.0361 0.0585
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0042 0.0306 0.3489
Plasmodium falciparum serine repeat antigen 7 0.0027 0.0147 0.1585
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.003 0.0183 0.0297
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0022 0.0099 0.016
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0022 0.0096 0.0412
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.0027 0.0147 0.0174
Schistosoma mansoni hypothetical protein 0.0038 0.0267 0.0314
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0023 0.0114 0.0134
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0023 0.0112 0.0112
Trichomonas vaginalis PIKK family atypical protein kinase 0.003 0.0183 0.0782
Echinococcus granulosus chromobox protein 1 0.0084 0.0743 0.0875
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) 0.0094 0.0849 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0023 0.0112 0.0112
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0042 0.0306 0.1503
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0023 0.0114 0.0184
Schistosoma mansoni cathepsin F (C01 family) 0.0042 0.0306 0.0361
Onchocerca volvulus Cathepsin F homolog 0.0042 0.0306 0.1307
Loa Loa (eye worm) hypothetical protein 0.0014 0.0015 0.0025
Echinococcus granulosus rhodopsin orphan GPCR 0.0023 0.0112 0.0132
Giardia lamblia Cathepsin B precursor 0.0206 0.2007 1
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0023 0.0114 0.0184
Trichomonas vaginalis penicillin-binding protein, putative 0.0043 0.0322 0.1378
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0044 0.0333 0.0392
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0029 0.0169 0.1937
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0014 0.0014 0.0016
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0016 0.0036 0.0036
Loa Loa (eye worm) fibroinase 0.0042 0.0306 0.0497
Schistosoma mansoni amine GPCR 0.0023 0.0112 0.0132
Plasmodium vivax vivapain-2 0.0042 0.0306 0.3489
Loa Loa (eye worm) phosphatidylinositol 3 0.0022 0.0099 0.016
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0023 0.0114 0.0184
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0042 0.0306 0.1503
Loa Loa (eye worm) hypothetical protein 0.0038 0.0267 0.0433
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0042 0.0306 0.3489
Loa Loa (eye worm) G-protein coupled receptor 0.0023 0.0112 0.0182
Echinococcus granulosus chromobox protein 1 0.0084 0.0743 0.0875
Plasmodium vivax acyl-CoA synthetase, putative 0.0021 0.0094 0.0945
Echinococcus multilocularis sex peptide receptor 0.0023 0.0112 0.0112
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0023 0.0114 0.0114
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0042 0.0306 0.1309
Trichomonas vaginalis PIKK family atypical protein kinase 0.0022 0.0099 0.0421
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.0027 0.0147 0.1585
Onchocerca volvulus 0.0023 0.0112 0.0477
Toxoplasma gondii preprocathepsin c precursor, putative 0.0027 0.0147 0.071
Plasmodium vivax serine-repeat antigen (SERA) 0.0027 0.0147 0.1585
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0023 0.0112 0.0132
Loa Loa (eye worm) hypothetical protein 0.0023 0.0112 0.0182
Echinococcus multilocularis dnaJ subfamily B 0.0494 0.4981 0.4981
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0031 0.019 0.0924
Loa Loa (eye worm) CHromoDomain protein family member 0.0016 0.0036 0.0058
Echinococcus granulosus cathepsin l cysteine peptidase 0.0042 0.0306 0.0361
Trichomonas vaginalis PIKK family atypical protein kinase 0.0022 0.0099 0.0421
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0022 0.0096 0.0412
Loa Loa (eye worm) heterochromatin protein 1 0.0084 0.0743 0.1206
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0042 0.0306 0.1309
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0023 0.0112 0.0132
Loa Loa (eye worm) hypothetical protein 0.0043 0.0322 0.0523
Trypanosoma cruzi cysteine peptidase, putative 0.0042 0.0306 0.0497
Mycobacterium tuberculosis Conserved protein 0.0043 0.0322 0.1157
Loa Loa (eye worm) hypothetical protein 0.0037 0.0255 0.0414
Giardia lamblia Cathepsin B-like cysteine proteinase 3 precursor 0.0027 0.0147 0.0256
Echinococcus multilocularis g protein coupled receptor 0.0023 0.0112 0.0112
Schistosoma mansoni opsin-like receptor 0.0023 0.0112 0.0132
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.012 0.1118 0.1815
Schistosoma mansoni hypothetical protein 0.0494 0.4981 0.5866
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0023 0.0112 0.0182
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0023 0.0112 0.0182
Toxoplasma gondii cathepsin CPC2 0.0027 0.0147 0.071
Onchocerca volvulus 0.0042 0.0306 0.1307
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0042 0.0306 0.1309
Echinococcus multilocularis Niemann Pick C1 protein 0.0119 0.1102 0.1102
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0042 0.0306 0.0497
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0278 0.2746 1
Plasmodium vivax vivapain-2 0.0042 0.0306 0.3489
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0023 0.0114 0.0134
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0014 0.0015 0.0135
Mycobacterium ulcerans acyl-CoA synthetase 0.0029 0.0169 0.1072
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0018 0.0059 0.0251
Leishmania major cathepsin L-like protease 0.0042 0.0306 0.1503
Loa Loa (eye worm) hypothetical protein 0.0015 0.0032 0.0051
Plasmodium falciparum acyl-CoA synthetase 0.0021 0.0094 0.0945
Trichomonas vaginalis PIKK family atypical protein kinase 0.0022 0.0099 0.0421
Loa Loa (eye worm) hypothetical protein 0.0023 0.0112 0.0182
Entamoeba histolytica cysteine protease, putative 0.0042 0.0306 0.2756
Schistosoma mansoni opsin-like receptor 0.0023 0.0112 0.0132
Schistosoma mansoni hypothetical protein 0.0082 0.0724 0.0853
Brugia malayi Cathepsin L-like precursor 0.0042 0.0306 0.0497
Loa Loa (eye worm) hypothetical protein 0.0023 0.0112 0.0182
Trichomonas vaginalis chromobox protein, putative 0.0084 0.0743 0.3176
Echinococcus multilocularis neuropeptide s receptor 0.0023 0.0112 0.0112
Echinococcus granulosus chromodomain helicase DNA binding protein 1 0.0014 0.0015 0.0018
Loa Loa (eye worm) hypothetical protein 0.0023 0.0112 0.0182
Entamoeba histolytica cysteine protease, putative 0.0042 0.0306 0.2756
Loa Loa (eye worm) hypothetical protein 0.0082 0.0724 0.1175
Loa Loa (eye worm) hypothetical protein 0.0023 0.0112 0.0182
Brugia malayi SET domain containing protein 0.0016 0.0034 0.0056
Trichomonas vaginalis PIKK family atypical protein kinase 0.0022 0.0099 0.0421
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0042 0.0306 0.1503
Brugia malayi G-protein coupled receptor 0.0023 0.0112 0.0182
Onchocerca volvulus 0.0023 0.0112 0.0477
Echinococcus multilocularis cathepsin L 0.0042 0.0306 0.0306
Brugia malayi M-phase phosphoprotein, mpp8 0.0014 0.0015 0.0025
Loa Loa (eye worm) hypothetical protein 0.003 0.0188 0.0305
Schistosoma mansoni chromobox protein 0.0014 0.0015 0.0018
Trichomonas vaginalis PIKK family atypical protein kinase 0.0022 0.0099 0.0421
Trypanosoma cruzi cruzipain precursor, putative 0.0042 0.0306 0.0497
Loa Loa (eye worm) hypothetical protein 0.0023 0.0112 0.0182
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0023 0.0114 0.0184
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0023 0.0114 0.0184
Trichomonas vaginalis chromobox protein, putative 0.0014 0.0015 0.0064
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) 0.0062 0.0513 0.6014
Loa Loa (eye worm) hypothetical protein 0.0023 0.0112 0.0182
Echinococcus granulosus cathepsin l1 0.0042 0.0306 0.0361
Giardia lamblia Cysteine protease 0.0027 0.0147 0.0256
Schistosoma mansoni hypothetical protein 0.0013 0.0005 0.0006
Echinococcus granulosus Niemann Pick C1 protein 0.0119 0.1102 0.1298
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0042 0.0306 0.1309
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0094 0.0849 1
Leishmania major cathepsin L-like protease 0.0042 0.0306 0.1503
Plasmodium falciparum dipeptidyl aminopeptidase 1 0.0027 0.0147 0.1585
Onchocerca volvulus 0.0037 0.0255 0.1089
Echinococcus multilocularis sterol regulatory element binding protein 0.0051 0.04 0.04
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0121 0.1121 0.1321
Trichomonas vaginalis chromobox protein, putative 0.0051 0.0398 0.1699
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0023 0.0112 0.0132
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0042 0.0306 0.1503
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0023 0.0112 0.0132
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0042 0.0306 0.1503
Echinococcus granulosus neuropeptides capa receptor 0.0023 0.0112 0.0132
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0022 0.0099 0.0466
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.004 0.0286 0.3321
Brugia malayi hypothetical protein 0.0023 0.0112 0.0182
Schistosoma mansoni hypothetical protein 0.0023 0.0112 0.0132
Brugia malayi Nuclear hormone receptor-like 1 0.0023 0.0114 0.0184
Schistosoma mansoni amine GPCR 0.0023 0.0112 0.0132
Onchocerca volvulus 0.0023 0.0114 0.0483
Brugia malayi Inositol-1 0.0045 0.0334 0.0542
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0014 0.0015 0.0018
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0023 0.0112 0.0112
Onchocerca volvulus 0.0044 0.0333 0.1421
Loa Loa (eye worm) hypothetical protein 0.0014 0.0015 0.0025
Echinococcus granulosus tm gpcr rhodopsin 0.0023 0.0112 0.0132
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0023 0.0114 0.0134
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.0027 0.0147 0.0239
Brugia malayi Latrophilin receptor protein 2 0.0038 0.0267 0.0433
Brugia malayi Associated with TFs and helicases family protein 0.0014 0.0015 0.0025
Echinococcus multilocularis expressed conserved protein 0.0112 0.1028 0.1028
Echinococcus multilocularis neuropeptide receptor 0.0023 0.0112 0.0112
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0023 0.0114 0.0114
Schistosoma mansoni survival motor neuron protein 0.0058 0.0475 0.056
Giardia lamblia Cathepsin L precursor 0.0027 0.0147 0.0256
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0027 0.0147 0.0174
Trichomonas vaginalis PIKK family atypical protein kinase 0.0014 0.0015 0.0062
Brugia malayi Cytochrome P450 family protein 0.0059 0.0482 0.0782
Trichomonas vaginalis chromobox protein, putative 0.0084 0.0743 0.3176
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0027 0.0147 0.063
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0147 0.063
Echinococcus multilocularis cathepsin L cysteine protease 0.0042 0.0306 0.0306
Loa Loa (eye worm) hypothetical protein 0.0023 0.0112 0.0182
Plasmodium vivax SET domain protein, putative 0.0031 0.019 0.21
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0094 0.0849 0.4216
Loa Loa (eye worm) hypothetical protein 0.0023 0.0112 0.0182
Brugia malayi Heterochromatin protein 1 0.0084 0.0743 0.1206
Echinococcus granulosus cysteine protease 0.0042 0.0306 0.0361
Entamoeba histolytica heat shock transcription factor, putative 0.012 0.1111 1
Loa Loa (eye worm) hypothetical protein 0.0023 0.0114 0.0184
Loa Loa (eye worm) neuropeptide F receptor 0.0023 0.0112 0.0182
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0042 0.0306 0.1309
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0022 0.0099 0.016
Echinococcus multilocularis rhodopsin orphan GPCR 0.0023 0.0112 0.0112
Trichomonas vaginalis chromobox protein, putative 0.0051 0.0398 0.1699
Echinococcus multilocularis orexin receptor type 2 0.0023 0.0112 0.0112
Brugia malayi larval opioid receptor 0.0023 0.0112 0.0182
Plasmodium vivax ataxin-2 like protein, putative 0.003 0.0188 0.2066
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0023 0.0114 0.0134
Mycobacterium tuberculosis Probable hydrolase 0.0043 0.0322 0.1157
Echinococcus granulosus neuropeptide Y receptor 0.0023 0.0112 0.0132
Trypanosoma brucei phosphatidylinositol kinase related protein, putative 0.003 0.0183 0.0887
Echinococcus multilocularis g protein coupled receptor 0.0023 0.0112 0.0112
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0042 0.0306 0.1309
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0045 0.0334 0.1642
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0023 0.0114 0.0184
Loa Loa (eye worm) hypothetical protein 0.0027 0.0147 0.0239
Loa Loa (eye worm) hypothetical protein 0.012 0.1111 0.1804
Echinococcus multilocularis inositol monophosphatase 1 0.0045 0.0334 0.0334
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0022 0.0099 0.016
Loa Loa (eye worm) hypothetical protein 0.0021 0.0094 0.0153
Brugia malayi fibroinase precursor 0.0027 0.0147 0.0239
Toxoplasma gondii LsmAD domain-containing protein 0.003 0.0188 0.091
Toxoplasma gondii cathepsin CPC1 0.0027 0.0147 0.071
Echinococcus multilocularis neuropeptide receptor 0.0023 0.0112 0.0112
Echinococcus multilocularis chromodomain helicase DNA binding protein 1 0.0014 0.0015 0.0015
Schistosoma mansoni histamine h1 receptor 0.0023 0.0112 0.0132
Brugia malayi hypothetical protein 0.0014 0.0015 0.0025
Loa Loa (eye worm) cytochrome P450 family protein 0.0013 0.0005 0.0009
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0023 0.0114 0.0184
Loa Loa (eye worm) hypothetical protein 0.0023 0.0112 0.0182
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0023 0.0114 0.0134
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0023 0.0112 0.0132
Schistosoma mansoni cathepsin S (C01 family) 0.0027 0.0147 0.0174
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0023 0.0114 0.0184
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0027 0.0147 0.063
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0206 0.2007 0.3258
Echinococcus granulosus cathepsin b 0.0608 0.6161 0.7255
Entamoeba histolytica cysteine protease, putative 0.0042 0.0306 0.2756
Loa Loa (eye worm) TYRA-2 protein 0.0023 0.0112 0.0182
Giardia lamblia Cysteine protease 0.0027 0.0147 0.0256
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0027 0.0147 0.0174
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0023 0.0112 0.0132
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0042 0.0306 0.1309
Brugia malayi Serotonin receptor 0.0023 0.0112 0.0182
Trichomonas vaginalis conserved hypothetical protein 0.0047 0.0361 0.1541
Brugia malayi cytochrome P450 0.0013 0.0005 0.0009
Trichomonas vaginalis D-aminoacylase, putative 0.0043 0.0322 0.1378
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0042 0.0306 0.1309
Brugia malayi cathepsin L-like cysteine proteinase 0.0027 0.0147 0.0239
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0042 0.0306 0.1309
Echinococcus granulosus inositol monophosphatase 1 0.0045 0.0334 0.0393
Loa Loa (eye worm) hypothetical protein 0.0119 0.1102 0.1789
Schistosoma mansoni hypothetical protein 0.0038 0.0267 0.0314
Loa Loa (eye worm) hypothetical protein 0.0023 0.0112 0.0182
Echinococcus granulosus G protein coupled receptor 139 0.0023 0.0112 0.0132
Onchocerca volvulus 0.0023 0.0112 0.0477
Schistosoma mansoni retinoic acid receptor RXR 0.0023 0.0114 0.0134
Echinococcus multilocularis serotonin receptor 0.0023 0.0112 0.0112
Brugia malayi Cytochrome P450 family protein 0.0013 0.0005 0.0009
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0023 0.0112 0.0112
Entamoeba histolytica cysteine proteinase, putative 0.0042 0.0306 0.2756
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0027 0.0147 0.0174
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0023 0.0112 0.0132
Entamoeba histolytica cysteine protease, putative 0.0027 0.0147 0.1326
Trichomonas vaginalis chromobox protein, putative 0.0014 0.0015 0.0064
Plasmodium falciparum cysteine proteinase falcipain 3 0.0042 0.0306 0.3489
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0022 0.0099 0.0466
Entamoeba histolytica cysteine proteinase, putative 0.0027 0.0147 0.1326
Mycobacterium tuberculosis Probable esterase LipL 0.0043 0.0322 0.1157
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0029 0.0169 0.0597
Trypanosoma cruzi PAB1-binding protein , putative 0.003 0.0188 0.0304
Toxoplasma gondii cathepsin CPL 0.0042 0.0306 0.1503
Echinococcus granulosus neuropeptide receptor 0.0023 0.0112 0.0132
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0022 0.0099 0.0886
Mycobacterium ulcerans acyl-CoA synthetase 0.0029 0.0169 0.1072
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0021 0.0094 0.0581
Onchocerca volvulus 0.0042 0.0306 0.1307
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0042 0.0306 0.1503
Entamoeba histolytica cysteine protease, putative 0.0042 0.0306 0.2756
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0042 0.0306 0.1309
Echinococcus granulosus g protein coupled receptor 0.0023 0.0112 0.0132
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0027 0.0147 0.0174
Entamoeba histolytica cysteine protease, putative 0.0042 0.0306 0.2756
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0014 0.0015 0.0064
Giardia lamblia Hypothetical protein 0.0027 0.0147 0.0256
Brugia malayi Papain family cysteine protease containing protein 0.0042 0.0306 0.0497
Brugia malayi steroid hormone receptor 0.0023 0.0114 0.0184
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0023 0.0112 0.0132
Echinococcus granulosus rhodopsin orphan GPCR 0.0023 0.0112 0.0132
Schistosoma mansoni neuropeptide receptor 0.0023 0.0112 0.0132
Brugia malayi G protein-coupled receptor 0.0023 0.0112 0.0182
Loa Loa (eye worm) hypothetical protein 0.0042 0.0306 0.0497
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0042 0.0306 0.1309
Trichomonas vaginalis conserved hypothetical protein 0.0051 0.04 0.1711
Entamoeba histolytica heat shock transcription factor, putative 0.012 0.1111 1
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0015 0.0064
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0031 0.019 0.019
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0023 0.0114 0.0134
Entamoeba histolytica cysteine protease, putative 0.0042 0.0306 0.2756
Echinococcus granulosus peptide allatostatin:somatostatin 0.0023 0.0112 0.0132
Toxoplasma gondii chromodomain helicase DNA binding protein CHD1/SWI2/SNF2 0.0014 0.0015 0.0049
Loa Loa (eye worm) hypothetical protein 0.0023 0.0112 0.0182
Schistosoma mansoni RAR-like nuclear receptor 0.0023 0.0114 0.0134
Echinococcus granulosus tm gpcr rhodopsin 0.0023 0.0112 0.0132
Echinococcus multilocularis chromobox protein 1 0.0084 0.0743 0.0743
Brugia malayi beta-lactamase family protein 0.0043 0.0322 0.0523
Plasmodium vivax serine-repeat antigen 5 (SERA) 0.0027 0.0147 0.1585
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0023 0.0112 0.0182
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.0027 0.0147 0.0174
Loa Loa (eye worm) hypothetical protein 0.0014 0.0015 0.0025
Onchocerca volvulus 0.0023 0.0112 0.0477
Brugia malayi hypothetical protein 0.0023 0.0112 0.0182
Entamoeba histolytica cysteine proteinase 1, putative 0.0042 0.0306 0.2756
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0023 0.0114 0.0184
Schistosoma mansoni biogenic amine (5HT) receptor 0.0023 0.0112 0.0132
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0017 0.0053 0.0225
Schistosoma mansoni amine GPCR 0.0023 0.0112 0.0132
Schistosoma mansoni biogenic amine receptor 0.0023 0.0112 0.0132
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0023 0.0114 0.0184
Loa Loa (eye worm) hypothetical protein 0.0014 0.0015 0.0025
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0038 0.0267 0.0314
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0042 0.0306 0.1503
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0042 0.0306 0.1309
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0016 0.0036 0.0042
Trypanosoma cruzi cytochrome P450, putative 0.0013 0.0005 0.0008
Entamoeba histolytica cysteine protease, putative 0.0042 0.0306 0.2756
Loa Loa (eye worm) hypothetical protein 0.0043 0.0322 0.0523
Loa Loa (eye worm) hypothetical protein 0.0608 0.6161 1
Echinococcus multilocularis chromobox protein 1 0.0084 0.0743 0.0743
Onchocerca volvulus 0.0023 0.0112 0.0477
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0027 0.0147 0.063
Trichomonas vaginalis conserved hypothetical protein 0.0047 0.0361 0.1541
Trichomonas vaginalis PIKK family atypical protein kinase 0.0022 0.0099 0.0421
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0033 0.0209 0.2326
Onchocerca volvulus 0.0042 0.0306 0.1307
Echinococcus multilocularis serine protein kinase ATM 0.003 0.0183 0.0183
Brugia malayi Papain family cysteine protease containing protein 0.0042 0.0306 0.0497
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0059 0.0251
Echinococcus granulosus ATP dependent Clp protease proteolytic subunit 0.0094 0.0849 0.1
Echinococcus granulosus rhodopsin orphan GPCR 0.0023 0.0112 0.0132
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0023 0.0112 0.0112
Plasmodium vivax vivapain-1 0.0042 0.0306 0.3489
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0023 0.0114 0.0184
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0042 0.0306 0.1309
Toxoplasma gondii target of rapamycin (TOR), putative 0.0022 0.0099 0.0466
Brugia malayi CHE-14 protein 0.0051 0.04 0.065
Loa Loa (eye worm) cytochrome P450 family protein 0.0059 0.0482 0.0782
Echinococcus granulosus Chromo domain 0.0014 0.0015 0.0018
Brugia malayi Probable ClpP-like protease 0.0094 0.0849 0.1379
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0042 0.0306 0.0361
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0027 0.0147 0.1326
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0022 0.0099 0.0466
Brugia malayi AMP-binding enzyme family protein 0.0029 0.0169 0.0274
Brugia malayi sulfakinin receptor protein 0.0023 0.0112 0.0182
Trichomonas vaginalis Clan CA, family C1, cathepsin F-like cysteine peptidase 0.0027 0.0147 0.063
Leishmania major cysteine peptidase A (CPA) 0.0042 0.0306 0.1503
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0023 0.0114 0.0184
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0015 0.0064
Echinococcus granulosus ecdysone induced protein 78C 0.0023 0.0114 0.0134
Loa Loa (eye worm) hypothetical protein 0.0023 0.0112 0.0182
Brugia malayi Papain family cysteine protease containing protein 0.0042 0.0306 0.0497
Giardia lamblia Cathepsin L precursor 0.0027 0.0147 0.0256
Loa Loa (eye worm) steroid hormone receptor 0.0023 0.0114 0.0184
Loa Loa (eye worm) hypothetical protein 0.0051 0.04 0.065
Schistosoma mansoni hypothetical protein 0.0049 0.0381 0.0449
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0042 0.0306 0.0361
Onchocerca volvulus 0.0023 0.0112 0.0477
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0023 0.0112 0.0132
Echinococcus multilocularis beta LACTamase domain containing family member 0.0043 0.0322 0.0322
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0042 0.0306 0.1309
Loa Loa (eye worm) cytochrome P450 family protein 0.0013 0.0005 0.0009
Echinococcus granulosus beta LACTamase domain containing family member 0.0043 0.0322 0.038
Loa Loa (eye worm) hypothetical protein 0.0027 0.0147 0.0239
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0042 0.0306 0.1503
Echinococcus granulosus neuropeptide receptor A26 0.0023 0.0112 0.0132
Echinococcus multilocularis neuropeptide Y receptor 0.0023 0.0112 0.0112
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0058 0.0475 0.0771
Onchocerca volvulus 0.0014 0.0015 0.0063
Echinococcus multilocularis survival motor neuron protein 1 0.0286 0.2826 0.2826
Brugia malayi hypothetical protein 0.0023 0.0112 0.0182
Brugia malayi photoreceptor-specific nuclear receptor 0.0023 0.0114 0.0184
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0023 0.0112 0.0112
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0043 0.0322 0.0523
Echinococcus multilocularis Chromo domain 0.0014 0.0015 0.0015
Onchocerca volvulus 0.0029 0.0169 0.072
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0043 0.0322 0.038
Trichomonas vaginalis Clan CA, family C1, cathepsin H-like cysteine peptidase 0.0027 0.0147 0.063
Plasmodium vivax serine-repeat antigen (SERA) 0.0027 0.0147 0.1585
Echinococcus granulosus cpg binding protein 0.0037 0.0252 0.0297
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0608 0.6161 0.7255
Loa Loa (eye worm) hypothetical protein 0.0023 0.0112 0.0182
Echinococcus multilocularis somatostatin receptor 0.0023 0.0112 0.0112
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0043 0.0322 0.0523
Schistosoma mansoni cpg binding protein 0.0035 0.0231 0.0273
Echinococcus granulosus sex peptide receptor 0.0023 0.0112 0.0132
Echinococcus granulosus neuropeptide FF receptor 2 0.0023 0.0112 0.0132
Mycobacterium ulcerans class a beta-lactamase, BlaC 0.016 0.153 1
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0022 0.0099 0.0466
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) 0.0062 0.0513 0.1852
Schistosoma mansoni cathepsin C 0.0027 0.0147 0.0174
Echinococcus multilocularis GPCR, family 2 0.0038 0.0267 0.0267
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0023 0.0112 0.0132
Loa Loa (eye worm) hypothetical protein 0.0023 0.0112 0.0182
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0022 0.0099 0.0466
Schistosoma mansoni neuropeptide receptor 0.0023 0.0112 0.0132
Loa Loa (eye worm) hypothetical protein 0.0027 0.0147 0.0239
Brugia malayi Pre-SET motif family protein 0.021 0.2041 0.3312
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0023 0.0112 0.0132
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0023 0.0112 0.0112
Mycobacterium tuberculosis Probable lipase LipE 0.0043 0.0322 0.1157
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0023 0.0114 0.0134
Echinococcus multilocularis cathepsin b 0.0608 0.6161 0.6161
Trichomonas vaginalis PIKK family atypical protein kinase 0.0022 0.0099 0.0421
Schistosoma mansoni cathepsin s 0.0015 0.0032 0.0037
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.004 0.0286 0.1023
Loa Loa (eye worm) inositol-1 0.0045 0.0334 0.0542
Echinococcus multilocularis ecdysone induced protein 78C 0.0023 0.0114 0.0114
Mycobacterium leprae conserved hypothetical protein 0.0043 0.0322 0.3756
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0022 0.0099 0.016
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0042 0.0306 0.0361
Loa Loa (eye worm) ctsf protein 0.0042 0.0306 0.0497
Echinococcus multilocularis chromobox protein 2 0.0014 0.0015 0.0015
Echinococcus granulosus hypothetical protein 0.0023 0.0112 0.0132
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0013 0.0005 0.0008
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0014 0.0015 0.0047
Echinococcus granulosus geminin 0.0205 0.1989 0.2343
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0014 0.0015 0.0064
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0029 0.0169 0.1072
Brugia malayi neuropeptide F receptor 0.0023 0.0112 0.0182
Brugia malayi nuclear receptor NHR-88 0.0023 0.0114 0.0184
Brugia malayi CXXC zinc finger family protein 0.0035 0.0231 0.0376
Echinococcus multilocularis fmrfamide receptor 0.0023 0.0112 0.0112
Echinococcus granulosus neuropeptide Y receptor 0.0023 0.0112 0.0132
Giardia lamblia Cathepsin B precursor 0.0027 0.0147 0.0256
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0023 0.0112 0.0132
Echinococcus multilocularis rhodopsin orphan GPCR 0.0023 0.0112 0.0112
Echinococcus multilocularis G protein coupled receptor 139 0.0023 0.0112 0.0112
Trypanosoma cruzi cysteine peptidase, putative 0.0042 0.0306 0.0497
Loa Loa (eye worm) hypothetical protein 0.0023 0.0114 0.0184
Giardia lamblia Cathepsin L precursor 0.0027 0.0147 0.0256
Brugia malayi AKH receptor 0.0023 0.0112 0.0182
Leishmania major phosphatidylinositol kinase related protein, putative 0.0022 0.0099 0.0468
Loa Loa (eye worm) hypothetical protein 0.0023 0.0114 0.0184
Echinococcus granulosus tm gpcr rhodopsin 0.0023 0.0112 0.0132
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0015 0.0064
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0042 0.0306 0.1309
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0014 0.0015 0.0135
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0023 0.0114 0.0184
Loa Loa (eye worm) hypothetical protein 0.0021 0.0094 0.0153
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0022 0.0096 0.0412
Echinococcus granulosus alpha 1A adrenergic receptor 0.0023 0.0112 0.0132
Brugia malayi Dopamine receptor protein 2 0.0023 0.0112 0.0182
Trypanosoma cruzi cysteine protease, putative 0.0042 0.0306 0.0497
Echinococcus multilocularis rhodopsin orphan GPCR 0.0023 0.0112 0.0112
Brugia malayi neuropeptide F receptor 0.0023 0.0112 0.0182
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0023 0.0112 0.0112
Brugia malayi cathepsin B-like cysteine proteinase 0.0608 0.6161 1
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0023 0.0114 0.0134
Plasmodium falciparum serine repeat antigen 3 0.0027 0.0147 0.1585
Entamoeba histolytica cysteine protease, putative 0.0042 0.0306 0.2756
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.002 0.0082 0.0279
Brugia malayi hypothetical protein 0.0023 0.0112 0.0182
Echinococcus multilocularis protein dispatched 1 0.0058 0.0475 0.0475
Plasmodium falciparum dipeptidyl aminopeptidase 2 0.0027 0.0147 0.1585
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0023 0.0114 0.0134
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0023 0.0114 0.0134
Brugia malayi cathepsin L-like precursor 0.0027 0.0147 0.0239
Brugia malayi hypothetical protein 0.002 0.0076 0.0123
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0023 0.0112 0.0132
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0051 0.0398 0.1698
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0023 0.0112 0.0112
Loa Loa (eye worm) hypothetical protein 0.0023 0.0112 0.0182
Schistosoma mansoni hypothetical protein 0.0058 0.0475 0.056
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0021 0.0094 0.0324
Loa Loa (eye worm) hypothetical protein 0.0029 0.0169 0.0274
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0027 0.0147 0.0174
Brugia malayi Cytochrome P450 family protein 0.0013 0.0005 0.0009
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0043 0.0322 0.1157
Echinococcus granulosus neuropeptides capa receptor 0.0023 0.0112 0.0132
Giardia lamblia Cysteine protease 0.0027 0.0147 0.0256
Onchocerca volvulus Heat shock factor protein 2 homolog 0.012 0.1111 0.4749
Onchocerca volvulus 0.0023 0.0112 0.0477
Brugia malayi G-protein coupled receptor 0.0023 0.0112 0.0182
Giardia lamblia Cathepsin L-like protease 0.0027 0.0147 0.0256
Brugia malayi Dopamine receptor 0.0023 0.0112 0.0182
Brugia malayi beta-lactamase family protein 0.0043 0.0322 0.0523
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0043 0.0322 0.038
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0022 0.0099 0.0466
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0014 0.0015 0.0049
Brugia malayi Cathepsin L-like precursor 0.0042 0.0306 0.0497
Entamoeba histolytica cysteine proteinase, putative 0.0042 0.0306 0.2756
Brugia malayi hypothetical protein 0.0023 0.0112 0.0182
Leishmania major cathepsin L-like protease 0.0042 0.0306 0.1503
Trichomonas vaginalis PIKK family atypical protein kinase 0.0022 0.0099 0.0421
Echinococcus granulosus Niemann Pick C1 protein 0.017 0.163 0.192
Brugia malayi Cathepsin L-like precursor 0.0042 0.0306 0.0497
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0027 0.0147 0.063
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0042 0.0306 0.1309
Schistosoma mansoni ataxia telangiectasia mutated (atm) 0.003 0.0183 0.0216
Loa Loa (eye worm) hypothetical protein 0.0023 0.0112 0.0182
Loa Loa (eye worm) hypothetical protein 0.0023 0.0112 0.0182
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0027 0.0147 0.063
Trypanosoma brucei PAB1-binding protein , putative 0.003 0.0188 0.091
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.002 0.0082 0.0279
Trichomonas vaginalis PIKK family atypical protein kinase 0.0022 0.0099 0.0421
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0045 0.0334 0.1428
Giardia lamblia Encystation-specific protease 0.0027 0.0147 0.0256
Entamoeba histolytica cysteine protease, putative 0.0042 0.0306 0.2756
Loa Loa (eye worm) hypothetical protein 0.0023 0.0112 0.0182
Entamoeba histolytica cysteine protease, putative 0.0042 0.0306 0.2756
Echinococcus granulosus biogenic amine 5HT receptor 0.0023 0.0112 0.0132
Loa Loa (eye worm) hypothetical protein 0.0043 0.0322 0.0523
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0022 0.0099 0.016
Loa Loa (eye worm) hypothetical protein 0.0023 0.0114 0.0184
Brugia malayi G protein-coupled receptor F59B2.13 0.0023 0.0112 0.0182
Onchocerca volvulus 0.0014 0.0015 0.0063
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0015 0.0064
Giardia lamblia Hypothetical protein 0.0027 0.0147 0.0256
Loa Loa (eye worm) CYP4Cod1 0.0013 0.0005 0.0009
Schistosoma mansoni thyroid hormone receptor 0.0023 0.0114 0.0134
Onchocerca volvulus Cathepsin L homolog 0.0027 0.0147 0.0628
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.019 0.0224
Leishmania major 4-coumarate:coa ligase-like protein 0.0029 0.0169 0.0817
Loa Loa (eye worm) phosphatidylinositol 3 0.0022 0.0099 0.016
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0027 0.0147 0.063
Loa Loa (eye worm) hypothetical protein 0.0023 0.0112 0.0182
Loa Loa (eye worm) hypothetical protein 0.0027 0.0147 0.0239
Echinococcus granulosus cathepsin l1 0.0027 0.0147 0.0174
Onchocerca volvulus 0.0023 0.0112 0.0477
Loa Loa (eye worm) hypothetical protein 0.0043 0.0322 0.0523
Plasmodium falciparum ataxin-2 like protein, putative 0.003 0.0188 0.2066
Entamoeba histolytica cysteine protease, putative 0.0042 0.0306 0.2756
Onchocerca volvulus 0.0023 0.0112 0.0477
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0023 0.0114 0.0134
Brugia malayi Steroid receptor seven-up type 2 0.0023 0.0114 0.0184
Plasmodium vivax vivapain-3 0.0042 0.0306 0.3489
Loa Loa (eye worm) hypothetical protein 0.0023 0.0114 0.0184
Loa Loa (eye worm) hypothetical protein 0.0023 0.0112 0.0182
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0023 0.0114 0.0184
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0023 0.0114 0.0184
Plasmodium vivax serine-repeat antigen 4 (SERA), putative 0.0027 0.0147 0.1585
Schistosoma mansoni biogenic amine (5HT) receptor 0.0023 0.0112 0.0132
Echinococcus multilocularis dro:myosuppressin receptor 0.0023 0.0112 0.0112
Echinococcus multilocularis FTZ F1 alpha 0.0023 0.0114 0.0114
Brugia malayi Type III restriction enzyme, res subunit family protein 0.0014 0.0015 0.0025
Schistosoma mansoni peptidase Clp (S14 family) 0.0094 0.0849 0.1
Loa Loa (eye worm) hypothetical protein 0.0094 0.0849 0.1379
Echinococcus granulosus Protein patched homolog 1 0.0051 0.04 0.0472
Brugia malayi Papain family cysteine protease containing protein 0.0027 0.0147 0.0239
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.002 0.0082 0.0279
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0023 0.0114 0.0483
Giardia lamblia Cathepsin B precursor 0.0206 0.2007 1
Schistosoma mansoni neuropeptide f receptor 76f 0.0023 0.0112 0.0132
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0042 0.0306 0.1309
Schistosoma mansoni neuropeptide F-like receptor 0.0023 0.0112 0.0132
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0022 0.0099 0.0466
Echinococcus multilocularis neuropeptides capa receptor 0.0023 0.0112 0.0112
Brugia malayi CHD4 protein 0.0016 0.0036 0.0058
Echinococcus granulosus survival motor neuron protein 1 0.0286 0.2826 0.3328
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0015 0.0064
Trichomonas vaginalis penicillin-binding protein, putative 0.0043 0.0322 0.1378
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0027 0.0147 0.1585
Echinococcus granulosus rhodopsin orphan GPCR 0.0023 0.0112 0.0132
Schistosoma mansoni nuclear hormone receptor 0.0023 0.0114 0.0134
Trichomonas vaginalis PIKK family atypical protein kinase 0.0022 0.0099 0.0421
Onchocerca volvulus 0.0027 0.0147 0.0628
Brugia malayi hypothetical protein 0.0023 0.0112 0.0182
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.003 0.0183 0.0297
Entamoeba histolytica heat shock transcription factor, putative 0.012 0.1111 1
Entamoeba histolytica hypothetical protein 0.003 0.0183 0.1646
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0023 0.0112 0.0132
Trichomonas vaginalis PIKK family atypical protein kinase 0.0022 0.0099 0.0421
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0022 0.0099 0.0886
Mycobacterium ulcerans hypothetical protein 0.0029 0.0169 0.1072
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0023 0.0112 0.0112
Loa Loa (eye worm) hypothetical protein 0.0023 0.0112 0.0182
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.0027 0.0147 0.1585
Brugia malayi Tachykinin-like peptides receptor 99D 0.0023 0.0112 0.0182
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0042 0.0306 0.1503
Mycobacterium leprae Probable lipase LipE 0.0043 0.0322 0.3756
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0027 0.0147 0.063
Echinococcus granulosus cathepsin L 0.0042 0.0306 0.0361
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0014 0.0015 0.0018
Loa Loa (eye worm) hypothetical protein 0.012 0.1118 0.1815
Brugia malayi hypothetical protein 0.0023 0.0112 0.0182
Brugia malayi Cytochrome P450 family protein 0.0013 0.0005 0.0009
Echinococcus granulosus neuropeptide s receptor 0.0023 0.0112 0.0132
Plasmodium falciparum cysteine proteinase falcipain 1 0.0042 0.0306 0.3489
Loa Loa (eye worm) hypothetical protein 0.0027 0.0147 0.0239
Trypanosoma cruzi hypothetical protein, conserved 0.0043 0.0322 0.0523
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0042 0.0306 0.1309
Echinococcus granulosus cathepsin L cysteine protease 0.0042 0.0306 0.0361
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.021 0.2041 0.3312
Trichomonas vaginalis Heterochromatin protein, putative 0.0014 0.0015 0.0064
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0027 0.0147 0.0239
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0094 0.0849 1
Loa Loa (eye worm) G-protein coupled receptor 0.0023 0.0112 0.0182
Schistosoma mansoni amine GPCR 0.0023 0.0112 0.0132
Brugia malayi Cathepsin L-like precursor 0.0042 0.0306 0.0497
Loa Loa (eye worm) hypothetical protein 0.0027 0.0147 0.0239
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0027 0.0147 0.063
Onchocerca volvulus 0.0035 0.0231 0.0987
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0045 0.0334 0.3006
Onchocerca volvulus 0.0023 0.0112 0.0477
Brugia malayi Cathepsin L-like precursor 0.0027 0.0147 0.0239
Echinococcus granulosus somatostatin receptor 0.0023 0.0112 0.0132
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0023 0.0112 0.0112
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0206 0.2007 0.2364
Giardia lamblia Cathepsin B precursor 0.0206 0.2007 1
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0045 0.0334 0.0542
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0016 0.0036 0.0042
Leishmania major cathepsin L-like protease 0.0042 0.0306 0.1503
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0023 0.0114 0.0184
Trypanosoma cruzi cruzipain precursor, putative 0.0015 0.0032 0.0051
Trypanosoma cruzi cysteine proteinase, putative 0.0042 0.0306 0.0497
Brugia malayi cathepsin Z-like cysteine proteinase 0.0027 0.0147 0.0239
Trichomonas vaginalis PIKK family atypical protein kinase 0.0022 0.0099 0.0421
Brugia malayi Cathepsin L-like cysteine proteinase 0.0027 0.0147 0.0239
Loa Loa (eye worm) hypothetical protein 0.0023 0.0112 0.0182
Giardia lamblia Cathepsin L precursor 0.0027 0.0147 0.0256
Giardia lamblia Cathepsin B precursor 0.0027 0.0147 0.0256
Toxoplasma gondii FATC domain-containing protein 0.003 0.0183 0.0887
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0094 0.0849 1
Onchocerca volvulus 0.0042 0.0306 0.1307
Echinococcus multilocularis g-protein coupled receptor 0.0023 0.0112 0.0112
Brugia malayi AMP-binding enzyme family protein 0.0029 0.0169 0.0274
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0027 0.0147 0.0174
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0023 0.0112 0.0132
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0042 0.0306 0.1309
Brugia malayi Papain family cysteine protease containing protein 0.0027 0.0147 0.0239
Loa Loa (eye worm) cysteine protease 0.0042 0.0306 0.0497
Brugia malayi Niemann-Pick C1 protein precursor 0.0119 0.1102 0.1789
Schistosoma mansoni patched 1 0.0051 0.04 0.0472
Brugia malayi Cathepsin L-like precursor 0.0042 0.0306 0.0497
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0023 0.0114 0.0184
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0023 0.0112 0.0132
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0022 0.0099 0.0116
Loa Loa (eye worm) pigment dispersing factor receptor c 0.012 0.1118 0.1815
Toxoplasma gondii histone lysine methyltransferase SET1 0.0067 0.0564 0.2789
Trypanosoma brucei hypothetical protein, conserved 0.0043 0.0322 0.1584
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0023 0.0114 0.0114
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0038 0.0267 0.0314
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0042 0.0306 0.1503
Mycobacterium leprae PROBABLE CONSERVED LIPOPROTEIN LPQF 0.0077 0.0668 0.7854
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0042 0.0306 0.1309
Schistosoma mansoni hypothetical protein 0.0014 0.0014 0.0016
Entamoeba histolytica cysteine protease, putative 0.0042 0.0306 0.2756
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0023 0.0112 0.0182
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0043 0.0322 0.2079
Toxoplasma gondii non-specific serine/threonine protein kinase 0.0014 0.0015 0.0047
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0094 0.0849 1
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0022 0.0096 0.0412
Loa Loa (eye worm) hypothetical protein 0.0015 0.0032 0.0051
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0023 0.0112 0.0132
Trichomonas vaginalis D-aminoacylase, putative 0.0043 0.0322 0.1378
Trypanosoma brucei cysteine peptidase C (CPC) 0.0206 0.2007 1
Echinococcus granulosus 7tm_1 domain containing protein 0.0023 0.0112 0.0132
Brugia malayi Dopamine receptor protein 1 0.0023 0.0112 0.0182
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0029 0.0169 0.1937
Brugia malayi Pre-SET motif family protein 0.0031 0.019 0.0309
Entamoeba histolytica cysteine proteinase, putative 0.0042 0.0306 0.2756
Plasmodium vivax unspecified product 0.0042 0.0306 0.3489
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0023 0.0114 0.0114
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0094 0.0849 0.5536
Schistosoma mansoni cpg binding protein 0.0037 0.0252 0.0297
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0022 0.0099 0.0099
Brugia malayi Papain family cysteine protease containing protein 0.0027 0.0147 0.0239
Loa Loa (eye worm) hypothetical protein 0.0027 0.0147 0.0239
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0023 0.0114 0.0134
Loa Loa (eye worm) hypothetical protein 0.0021 0.0094 0.0153
Entamoeba histolytica cysteine proteinase, putative 0.0042 0.0306 0.2756
Schistosoma mansoni cathepsin B (C01 family) 0.0027 0.0147 0.0174
Entamoeba histolytica acyl-CoA synthetase, putative 0.0029 0.0169 0.1519
Onchocerca volvulus 0.0023 0.0112 0.0477
Echinococcus granulosus g protein coupled receptor 0.0023 0.0112 0.0132
Leishmania major 4-coumarate:coa ligase-like protein 0.0029 0.0169 0.0817
Trichomonas vaginalis Clan CA, family C1, cathepsin L or H-like cysteine peptidase 0.0027 0.0147 0.063

Activities

Activity type Activity value Assay description Source Reference
AC50 (functional) PUBCHEM_BIOASSAY: Cytochrome panel assay with activity outcomes. (Class of assay: other) Panel member name: p450-cyp2d6 Compounds with AC50 equal or less than 10 uM are considered active ChEMBL. No reference
AC50 (functional) PUBCHEM_BIOASSAY: Cytochrome panel assay with activity outcomes. (Class of assay: other) Panel member name: p450-cyp3a4 Compounds with AC50 equal or less than 10 uM are considered active ChEMBL. No reference
AC50 (functional) = 2.818382931 uM PUBCHEM_BIOASSAY: Cytochrome panel assay with activity outcomes. (Class of assay: other) Panel member name: p450-cyp2c9 Compounds with AC50 equal or less than 10 uM are considered active ChEMBL. No reference
AC50 (functional) = 4.466835922 uM PUBCHEM_BIOASSAY: Cytochrome panel assay with activity outcomes. (Class of assay: other) Panel member name: p450-cyp2c19 Compounds with AC50 equal or less than 10 uM are considered active ChEMBL. No reference
AC50 (functional) = 5.011872336 uM PUBCHEM_BIOASSAY: Cytochrome panel assay with activity outcomes. (Class of assay: other) Panel member name: p450-cyp1a2 Compounds with AC50 equal or less than 10 uM are considered active ChEMBL. No reference
EC50 (functional) < 0.16 um PUBCHEM_BIOASSAY: Luminescence Cell-Based Dose Confirmation HTS to Identify Inhibitors of Heat Shock Factor 1 (HSF1). (Class of assay: confirmatory) [Related pubchem assays: 2118 (Project Summary), 2098 (Primary HTS)] ChEMBL. No reference
IC50 (binding) = 3.499 uM PUBCHEM_BIOASSAY: Fluorescence-based cell-based high throughput dose response assay for inhibitors of TLR9-MyD88 binding. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504734, AID504750, AID540250, AID540251] ChEMBL. No reference
IC50 (binding) = 3.698 uM PUBCHEM_BIOASSAY: Counterscreen for inhibitors of TLR9-MyD88 binding: fluorescence-based cell-based high throughput dose response assay to identify non-selective inhibitors of the beta-lactamase enzyme (BLA). (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504734, AID504750, AID540250, AID540251] ChEMBL. No reference
Potency (functional) 0.1636 uM PUBCHEM_BIOASSAY: qHTS screen for small molecules that induce genotoxicity in human embryonic kidney (HEK293T) cells expressing luciferase-tagged ELG1. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID493106, AID493143] ChEMBL. No reference
Potency (functional) 0.2617 uM PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 48 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488752, AID488774, AID504848, AID504850] ChEMBL. No reference
Potency (functional) 0.3013 uM PUBCHEM_BIOASSAY: qHTS profiling assay for firefly luciferase inhibitor/activator using purified enzyme and Km concentrations of substrates (counterscreen for miR-21 project). (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID2288, AID2289, AID2598, AID411] ChEMBL. No reference
Potency (functional) = 0.3162 um PUBCHEM_BIOASSAY: qHTS Assay for NPC1 Promoter Activators. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 0.3663 uM PUBCHEM_BIOASSAY: qHTS screen for small molecules that inhibit ELG1-dependent DNA repair in human embryonic kidney (HEK293T) cells expressing luciferase-tagged ELG1. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID493107, AID493125] ChEMBL. No reference
Potency (functional) = 0.4467 um PUBCHEM_BIOASSAY: qHTS Assay for Rab9 Promoter Activators. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 0.5012 um PUBCHEM_BIOASSAY: qHTS Assay for Enhancers of SMN2 Splice Variant Expression. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 0.631 um PUBCHEM_BIOASSAY: qHTS Inhibitors of AmpC Beta-Lactamase (assay with detergent). (Class of assay: confirmatory) [Related pubchem assays: 1002 (Confirmation Concentration-Response Assay for Inhibitors of AmpC Beta-Lactamase (assay with detergent)), 585 (Promiscuous and Specific Inhibitors of AmpC Beta-Lactamase (assay without detergent) - a screen old NIH MLSMR collection), 584 (Promiscuous and Specific Inhibitors of AmpC Beta-Lactamase (assay with detergent) - a screen of the old NIH MLSMR collection), 1003 (Confirmation Cuvette-Based Assay for Inhibitors of AmpC Beta-Lactamase (assay with detergent))] ChEMBL. No reference
Potency (functional) 0.7375 uM PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488745, AID488752, AID488774, AID504848, AID504850] ChEMBL. No reference
Potency (functional) 1.9953 uM PubChem BioAssay. qHTS of GLP-1 Receptor Inverse Agonists (Inhibition Mode). (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 2.8184 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors Targeting the Menin-MLL Interaction in MLL Related Leukemias: Competition With Texas Red Labeled MLL-derived Mutant Peptide. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 5.8048 uM PubChem BioAssay. A quantitative high throughput screen for small molecules that induce DNA re-replication in SW480 colon adenocarcinoma cells. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 7.0795 um PUBCHEM_BIOASSAY: qHTS for inhibitors of ROR gamma transcriptional activity. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 8.9125 uM PubChem BioAssay. qHTS for Inhibitors of ATXN expression. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 9.1962 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of binding or entry into cells for Lassa Virus. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID463114, AID540249] ChEMBL. No reference
Potency (functional) 9.2 uM PubChem BioAssay. A quantitative high throughput screen for small molecules that induce DNA re-replication in MCF 10a normal breast cells. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 10 um PUBCHEM_BIOASSAY: VP16 counterscreen qHTS for inhibitors of ROR gamma transcriptional activity. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 12.5893 uM PubChem BioAssay. qHTS Assay for Activators of ClpP. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 15.8489 um PUBCHEM_BIOASSAY: Counterscreen qHTS for Inhibitors of Tau Fibril Formation, Fluorescence Polarization. This assay monitors tau fibrillation by fluorescence polarization (FP) of Alexa 594-labeled K18 P301L, which does not fibrillize readily but incorporates into growing filaments of unlabeled tau. (Class of assay: confirmatory) [Related pubchem assays: 596 ] ChEMBL. No reference
Potency (functional) = 15.8489 um PUBCHEM_BIOASSAY: Confirmation Assay for Identifying the Cell-Membrane Permeable IMPase Inhibitors. (Class of assay: confirmatory) [Related pubchem assays: 1457, 901 ] ChEMBL. No reference
Potency (functional) 17.7828 uM PUBCHEM_BIOASSAY: HTS for Inhibitors of HP1-beta Chromodomain Interactions with Methylated Histone Tails. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488962] ChEMBL. No reference
Potency (functional) 17.7828 uM PubChem BioAssay. qHTS of PTHR Inhibitors: Primary Screen. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 19.9526 um PUBCHEM_BIOASSAY: qHTS Assay for Identifying a Potential Treatment of Ataxia-Telangiectasia. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 25.1189 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of HPGD (15-Hydroxyprostaglandin Dehydrogenase). (Class of assay: confirmatory) [Related pubchem assays: 2429 (Confirmation qHTS Assay for Inhibitors of HPGD (15-Hydroxyprostaglandin Dehydrogenase)), 2407 (Probe Development Summary for Inhibitors of HPGD (15-Hydroxyprostaglandin Dehydrogenase)), 2427 (Thermal Shift Assay for Inhibitors of HPGD (15-Hydroxyprostaglandin Dehydrogenase))] ChEMBL. No reference
Potency (functional) 25.1189 uM PubChem BioAssay. Inhibitors of Secretory Acid Sphingomyelinase (S-ASM): qHTS. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 28.1838 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Human Jumonji Domain Containing 2E (JMJD2E). (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 28.1838 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Aldehyde Dehydrogenase 1 (ALDH1A1). (Class of assay: confirmatory) [Related pubchem assays: 1030 (qHTS Validation Assay for Inhibitors of aldehyde dehydrogenase 1 (ALDH1A1))] ChEMBL. No reference
Potency (functional) 29.0929 uM PUBCHEM_BIOASSAY: Nrf2 qHTS screen for inhibitors. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID493153, AID493163, AID504648] ChEMBL. No reference
Potency (functional) = 31.6228 um PUBCHEM_BIOASSAY: qHTS Assay for Identifying the Cell-Membrane Permeable IMPase Inhibitors. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 39.8107 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of RanGTP induced Rango (Ran-regulated importin-beta cargo) - Importin beta complex dissociation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID540262] ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Homo sapiens ChEMBL23
Plasmodium falciparum ChEMBL23

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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