Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | hypothetical protein | 0.0033 | 0.5926 | 0.5926 |
Trypanosoma cruzi | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0014 | 0 | 0.5 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0031 | 0.5368 | 0.5368 |
Schistosoma mansoni | hypothetical protein | 0.0031 | 0.5368 | 0.9059 |
Plasmodium vivax | isocitrate dehydrogenase [NADP], mitochondrial, putative | 0.0014 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0045 | 1 | 1 |
Mycobacterium tuberculosis | Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) | 0.0014 | 0 | 0.5 |
Trypanosoma brucei | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0014 | 0 | 0.5 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0045 | 1 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0033 | 0.5926 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0033 | 0.5926 | 0.5 |
Trypanosoma brucei | isocitrate dehydrogenase, putative | 0.0014 | 0 | 0.5 |
Toxoplasma gondii | isocitrate dehydrogenase | 0.0014 | 0 | 0.5 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0033 | 0.5926 | 1 |
Plasmodium falciparum | isocitrate dehydrogenase [NADP], mitochondrial | 0.0014 | 0 | 0.5 |
Entamoeba histolytica | hypothetical protein | 0.0033 | 0.5926 | 0.5 |
Trypanosoma cruzi | isocitrate dehydrogenase, putative | 0.0014 | 0 | 0.5 |
Entamoeba histolytica | hypothetical protein | 0.0033 | 0.5926 | 0.5 |
Leishmania major | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0014 | 0 | 0.5 |
Toxoplasma gondii | isocitrate dehydrogenase | 0.0014 | 0 | 0.5 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0045 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.5368 | 0.5368 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0033 | 0.5926 | 1 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0033 | 0.5926 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0033 | 0.5926 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.