Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0033 | 0 | 0.5 |
Onchocerca volvulus | 0.0033 | 0 | 0.5 | |
Giardia lamblia | Aldose reductase | 0.0033 | 0 | 0.5 |
Entamoeba histolytica | aldose reductase, putative | 0.0033 | 0 | 0.5 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0033 | 0 | 0.5 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0033 | 0 | 0.5 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0033 | 0 | 0.5 |
Toxoplasma gondii | aldose reductase, putative | 0.0033 | 0 | 0.5 |
Onchocerca volvulus | 0.0033 | 0 | 0.5 | |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0033 | 0 | 0.5 |
Schistosoma mansoni | tar DNA-binding protein | 0.0062 | 1 | 1 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0033 | 0 | 0.5 |
Leishmania major | prostaglandin f2-alpha synthase/D-arabinose dehydrogenase | 0.0033 | 0 | 0.5 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0033 | 0 | 0.5 |
Onchocerca volvulus | 0.0033 | 0 | 0.5 | |
Leishmania major | prostaglandin f synthase, putative | 0.0033 | 0 | 0.5 |
Trypanosoma brucei | aldo-keto reductase, putative | 0.0033 | 0 | 0.5 |
Mycobacterium ulcerans | oxidoreductase | 0.0033 | 0 | 0.5 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0033 | 0 | 0.5 |
Mycobacterium leprae | PROBABLE OXIDOREDUCTASE | 0.0033 | 0 | 0.5 |
Onchocerca volvulus | 0.0033 | 0 | 0.5 | |
Giardia lamblia | Aldose reductase | 0.0033 | 0 | 0.5 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0033 | 0 | 0.5 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0033 | 0 | 0.5 |
Onchocerca volvulus | 0.0033 | 0 | 0.5 | |
Trichomonas vaginalis | aldo/keto reductase, putative | 0.0033 | 0 | 0.5 |
Echinococcus multilocularis | tar DNA binding protein | 0.0062 | 1 | 1 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0033 | 0 | 0.5 |
Schistosoma mansoni | tar DNA-binding protein | 0.0062 | 1 | 1 |
Brugia malayi | TAR-binding protein | 0.0062 | 1 | 1 |
Trichomonas vaginalis | aldo/keto reductase, putative | 0.0033 | 0 | 0.5 |
Entamoeba histolytica | aldose reductase, putative | 0.0033 | 0 | 0.5 |
Trichomonas vaginalis | dihydrodiol dehydrogenase, putative | 0.0033 | 0 | 0.5 |
Trypanosoma brucei | prostaglandin f synthase | 0.0033 | 0 | 0.5 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0033 | 0 | 0.5 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0033 | 0 | 0.5 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0062 | 1 | 1 |
Trichomonas vaginalis | aldo/keto reductase, putative | 0.0033 | 0 | 0.5 |
Onchocerca volvulus | 0.0033 | 0 | 0.5 | |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0062 | 1 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0062 | 1 | 1 |
Echinococcus granulosus | tar DNA binding protein | 0.0062 | 1 | 1 |
Trypanosoma cruzi | aldo-keto reductase | 0.0033 | 0 | 0.5 |
Schistosoma mansoni | tar DNA-binding protein | 0.0062 | 1 | 1 |
Loa Loa (eye worm) | TAR-binding protein | 0.0062 | 1 | 1 |
Loa Loa (eye worm) | RNA binding protein | 0.0062 | 1 | 1 |
Leishmania major | aldehyde reductase, putative,oxidoreductase, putative | 0.0033 | 0 | 0.5 |
Trichomonas vaginalis | dihydrodiol dehydrogenase, putative | 0.0033 | 0 | 0.5 |
Schistosoma mansoni | tar DNA-binding protein | 0.0062 | 1 | 1 |
Entamoeba histolytica | aldose reductase, putative | 0.0033 | 0 | 0.5 |
Trichomonas vaginalis | dihydrodiol dehydrogenase, putative | 0.0033 | 0 | 0.5 |
Trypanosoma cruzi | aldo/keto reductase, putative | 0.0033 | 0 | 0.5 |
Leishmania major | aldo-keto reductase-like protein | 0.0033 | 0 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.