Detailed information for compound 713766

Basic information

Technical information
  • TDR Targets ID: 713766
  • Name: N-cyclohexyl-5-fluoro-2-methoxybenzenesulfona mide
  • MW: 287.35 | Formula: C13H18FNO3S
  • H donors: 1 H acceptors: 2 LogP: 2.77 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: COc1ccc(cc1S(=O)(=O)NC1CCCCC1)F
  • InChi: 1S/C13H18FNO3S/c1-18-12-8-7-10(14)9-13(12)19(16,17)15-11-5-3-2-4-6-11/h7-9,11,15H,2-6H2,1H3
  • InChiKey: JTYWBTWYSZPDNK-UHFFFAOYSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

  • N-cyclohexyl-5-fluoro-2-methoxy-benzenesulfonamide
  • ZINC00528354
  • ALD-N038040

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0047 0.017 0.0532
Toxoplasma gondii type I fatty acid synthase, putative 0.0077 0.0355 0.2146
Schistosoma mansoni biogenic amine (5HT) receptor 0.0028 0.0049 0.0121
Onchocerca volvulus 0.0028 0.0049 0.0167
Schistosoma mansoni opsin-like receptor 0.0028 0.0049 0.0121
Echinococcus multilocularis fmrfamide receptor 0.0028 0.0049 0.0049
Loa Loa (eye worm) hypothetical protein 0.0106 0.0532 0.0661
Echinococcus multilocularis neuropeptide Y receptor 0.0028 0.0049 0.0049
Brugia malayi hypothetical protein 0.0028 0.0049 0.0061
Echinococcus granulosus histone lysine methyltransferase setb 0.008 0.0371 0.0462
Brugia malayi ORL1-like opioid receptor 0.0028 0.0049 0.0061
Loa Loa (eye worm) hypothetical protein 0.004 0.0127 0.0158
Loa Loa (eye worm) hypothetical protein 0.1323 0.8043 1
Loa Loa (eye worm) hypothetical protein 0.008 0.0371 0.0462
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0028 0.0049 0.0061
Onchocerca volvulus 0.0068 0.0297 0.1008
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0028 0.0049 0.0049
Loa Loa (eye worm) hypothetical protein 0.0028 0.0049 0.0061
Trichomonas vaginalis CAMK family protein kinase 0.0099 0.0492 0.1627
Loa Loa (eye worm) acetyltransferase 0.0155 0.0834 0.1037
Brugia malayi mbt repeat family protein 0.0048 0.0174 0.0216
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0106 0.0532 0.1305
Loa Loa (eye worm) hypothetical protein 0.0106 0.0532 0.0661
Schistosoma mansoni gliotactin 0.0106 0.0532 0.1305
Loa Loa (eye worm) G-protein coupled receptor 0.0028 0.0049 0.0061
Loa Loa (eye worm) hypothetical protein 0.0028 0.0049 0.0061
Brugia malayi Dopamine receptor protein 2 0.0028 0.0049 0.0061
Schistosoma mansoni hypothetical protein 0.0095 0.0464 0.1138
Loa Loa (eye worm) hypothetical protein 0.0028 0.0049 0.0061
Echinococcus multilocularis GPCR, family 2 0.0095 0.0464 0.0464
Echinococcus multilocularis acetylcholinesterase 0.0627 0.3745 0.3745
Echinococcus multilocularis rhodopsin orphan GPCR 0.0028 0.0049 0.0049
Echinococcus multilocularis neuropeptide receptor 0.0028 0.0049 0.0049
Schistosoma mansoni hypothetical protein 0.0095 0.0464 0.1138
Echinococcus granulosus Alpha N acetylgalactosaminidase 0.0115 0.0587 0.0729
Echinococcus granulosus carboxylesterase 5A 0.0627 0.3745 0.4656
Echinococcus multilocularis rhodopsin orphan GPCR 0.0028 0.0049 0.0049
Brugia malayi Carboxylesterase family protein 0.0627 0.3745 0.4656
Mycobacterium tuberculosis Probable multifunctional mycocerosic acid synthase membrane-associated Mas 0.0077 0.0355 0.2345
Echinococcus multilocularis muscleblind protein 0.1323 0.8043 0.8043
Toxoplasma gondii melibiase subfamily protein 0.0115 0.0587 0.3943
Echinococcus multilocularis chromobox protein 1 0.0073 0.0331 0.0331
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0241 0.1368 1
Loa Loa (eye worm) hypothetical protein 0.004 0.0127 0.0158
Mycobacterium tuberculosis Probable polyketide synthase Pks7 0.0077 0.0355 0.2345
Loa Loa (eye worm) hypothetical protein 0.0045 0.0154 0.0191
Entamoeba histolytica serine/threonine protein kinase, putative 0.0099 0.0492 1
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0044 0.015 0.0186
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.006 0.0251 0.0313
Echinococcus granulosus somatostatin receptor 0.0028 0.0049 0.0061
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0258 0.0633
Loa Loa (eye worm) hypothetical protein 0.004 0.0127 0.0158
Onchocerca volvulus 0.0106 0.0532 0.1802
Echinococcus multilocularis muscleblind protein 1 0.1323 0.8043 0.8043
Mycobacterium ulcerans Type I modular polyketide synthase 0.0073 0.0327 0.2298
Brugia malayi hypothetical protein 0.0028 0.0049 0.0061
Echinococcus granulosus g protein coupled receptor 0.0028 0.0049 0.0061
Mycobacterium ulcerans thioesterase TesA 0.0061 0.0252 0.1745
Mycobacterium ulcerans beta-lactamase 0.004 0.0127 0.0821
Echinococcus granulosus BC026374 protein S09 family 0.0106 0.0532 0.0661
Loa Loa (eye worm) hypothetical protein 0.0028 0.0049 0.0061
Echinococcus multilocularis family S9 non peptidase ue (S09 family) 0.0106 0.0532 0.0532
Brugia malayi Pre-SET motif family protein 0.0438 0.2578 0.3205
Onchocerca volvulus 0.0028 0.0049 0.0167
Echinococcus multilocularis rhodopsin orphan GPCR 0.0028 0.0049 0.0049
Trichomonas vaginalis chromobox protein, putative 0.0044 0.0151 0.0468
Schistosoma mansoni neuropeptide receptor 0.0028 0.0049 0.0121
Loa Loa (eye worm) hypothetical protein 0.0028 0.0049 0.0061
Loa Loa (eye worm) RNA binding protein 0.0062 0.0258 0.0321
Mycobacterium ulcerans esterase/lipase LipP 0.004 0.0127 0.0821
Echinococcus multilocularis neuroligin 0.0106 0.0532 0.0532
Loa Loa (eye worm) hypothetical protein 0.0028 0.0049 0.0061
Onchocerca volvulus 0.0028 0.0049 0.0167
Trypanosoma brucei polo-like protein kinase 0.0099 0.0492 1
Loa Loa (eye worm) hypothetical protein 0.0028 0.0049 0.0061
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0037 0.0105 0.0211
Schistosoma mansoni lipoxygenase 0.0031 0.0068 0.0167
Echinococcus multilocularis Glycoside hydrolase, family 27 0.0115 0.0587 0.0587
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0064 0.0271 0.0271
Echinococcus granulosus SAM and MBT domain containing protein 0.0048 0.0174 0.0216
Loa Loa (eye worm) hypothetical protein 0.0077 0.0351 0.0436
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0028 0.0049 0.0061
Brugia malayi G protein-coupled receptor F59B2.13 0.0028 0.0049 0.0061
Schistosoma mansoni importin beta-1 0.0032 0.0078 0.0191
Brugia malayi hypothetical protein 0.0495 0.293 0.3643
Echinococcus multilocularis histone acetyltransferase MYST2 0.0055 0.0215 0.0215
Loa Loa (eye worm) hypothetical protein 0.0028 0.0049 0.0061
Echinococcus granulosus sex peptide receptor 0.0028 0.0049 0.0061
Echinococcus multilocularis para nitrobenzyl esterase 0.0106 0.0532 0.0532
Echinococcus multilocularis neuropeptides capa receptor 0.0028 0.0049 0.0049
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0345 0.2006 0.2494
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0077 0.0351 0.086
Loa Loa (eye worm) hypothetical protein 0.0106 0.0532 0.0661
Loa Loa (eye worm) hypothetical protein 0.0028 0.0049 0.0061
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.004 0.0127 0.0821
Echinococcus granulosus dro:myosuppressin receptor 0.0028 0.0049 0.0061
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0095 0.0464 0.0577
Loa Loa (eye worm) hypothetical protein 0.0032 0.0077 0.0096
Schistosoma mansoni amine GPCR 0.0028 0.0049 0.0121
Loa Loa (eye worm) heterochromatin protein 1 0.0073 0.0331 0.0411
Echinococcus granulosus g protein coupled receptor 0.0028 0.0049 0.0061
Mycobacterium ulcerans polyketide synthase 0.0077 0.0355 0.2504
Loa Loa (eye worm) hypothetical protein 0.0028 0.0049 0.0061
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0115 0.0587 0.1439
Mycobacterium tuberculosis Conserved protein 0.004 0.0127 0.0782
Loa Loa (eye worm) hypothetical protein 0.0495 0.293 0.3643
Schistosoma mansoni biogenic amine receptor 0.0028 0.0049 0.0121
Echinococcus granulosus G protein coupled receptor 139 0.0028 0.0049 0.0061
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0068 0.0297 0.037
Toxoplasma gondii type I fatty acid synthase, putative 0.0052 0.0198 0.0929
Brugia malayi Carboxylesterase family protein 0.0106 0.0532 0.0661
Mycobacterium ulcerans aldehyde dehydrogenase 0.0241 0.1368 1
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsC 0.0073 0.0327 0.2153
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0028 0.0049 0.0061
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0037 0.0105 0.0668
Echinococcus multilocularis neuropeptide receptor 0.0028 0.0049 0.0049
Onchocerca volvulus 0.0106 0.0532 0.1802
Brugia malayi hypothetical protein 0.0028 0.0049 0.0061
Echinococcus granulosus acetylcholinesterase 0.0627 0.3745 0.4656
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0028 0.0049 0.0121
Loa Loa (eye worm) neuropeptide F receptor 0.0028 0.0049 0.0061
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0099 0.0492 0.0611
Schistosoma mansoni chromobox protein 0.0073 0.0331 0.0811
Echinococcus granulosus neuroligin 0.0106 0.0532 0.0661
Brugia malayi hypothetical protein 0.0028 0.0049 0.0061
Mycobacterium ulcerans polyketide synthase Pks9 0.0048 0.0175 0.1174
Onchocerca volvulus 0.0028 0.0049 0.0167
Echinococcus multilocularis polycomb protein SCMH1 0.0048 0.0174 0.0174
Loa Loa (eye worm) hypothetical protein 0.0028 0.0049 0.0061
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0028 0.0049 0.0121
Schistosoma mansoni hypothetical protein 0.068 0.4076 1
Onchocerca volvulus 0.0028 0.0049 0.0167
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsA 0.0073 0.0327 0.2153
Loa Loa (eye worm) hypothetical protein 0.0028 0.0049 0.0061
Mycobacterium ulcerans aldehyde dehydrogenase 0.0241 0.1368 1
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0097 0.0478 0.1173
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0095 0.0464 0.0577
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0047 0.017 0.0713
Schistosoma mansoni neuropeptide receptor 0.0028 0.0049 0.0121
Brugia malayi Bromodomain containing protein 0.0042 0.0139 0.0173
Echinococcus multilocularis rhodopsin orphan GPCR 0.0028 0.0049 0.0049
Loa Loa (eye worm) carboxylesterase 0.0106 0.0532 0.0661
Loa Loa (eye worm) hypothetical protein 0.0028 0.0049 0.0061
Echinococcus multilocularis fmrfamide receptor 0.0028 0.0049 0.0049
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0064 0.0271 0.0337
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0097 0.0478 0.0594
Schistosoma mansoni neuroligin 3 (S09 family) 0.0106 0.0532 0.1305
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSA 0.0073 0.0327 0.581
Echinococcus granulosus 7tm_1 domain containing protein 0.0028 0.0049 0.0061
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0036 0.0101 0.0101
Mycobacterium tuberculosis Probable fatty acid synthase Fas (fatty acid synthetase) 0.0023 0.0019 0.004
Mycobacterium tuberculosis Probable membrane bound polyketide synthase Pks6 0.0109 0.0549 0.3677
Toxoplasma gondii beta-ketoacyl synthase, N-terminal domain-containing protein 0.0047 0.0169 0.071
Brugia malayi beta-lactamase family protein 0.004 0.0127 0.0158
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0155 0.0834 0.2045
Echinococcus multilocularis neuropeptide receptor A26 0.0028 0.0049 0.0049
Loa Loa (eye worm) beta-lactamase 0.004 0.0127 0.0158
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0037 0.0105 0.5096
Loa Loa (eye worm) hypothetical protein 0.0028 0.0049 0.0061
Loa Loa (eye worm) G-protein coupled receptor 0.0028 0.0049 0.0061
Schistosoma mansoni survival motor neuron protein 0.0101 0.0501 0.1229
Brugia malayi AKH receptor 0.0028 0.0049 0.0061
Trypanosoma cruzi hypothetical protein, conserved 0.004 0.0127 0.1933
Schistosoma mansoni amine GPCR 0.0028 0.0049 0.0121
Brugia malayi Serotonin receptor 0.0028 0.0049 0.0061
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0055 0.0215 0.0215
Echinococcus granulosus neuropeptide receptor A26 0.0028 0.0049 0.0061
Mycobacterium tuberculosis Probable polyketide synthase Pks1 0.0052 0.0201 0.1285
Brugia malayi Carboxylesterase family protein 0.0106 0.0532 0.0661
Loa Loa (eye worm) hypothetical protein 0.0106 0.0532 0.0661
Trichomonas vaginalis CAMK family protein kinase 0.0049 0.0182 0.0573
Schistosoma mansoni ap endonuclease 0.0037 0.0105 0.0259
Toxoplasma gondii aldehyde dehydrogenase 0.0241 0.1368 1
Brugia malayi oxidoreductase, zinc-binding dehydrogenase family protein 0.0138 0.0728 0.0906
Brugia malayi hypothetical protein 0.0028 0.0049 0.0061
Onchocerca volvulus 0.0028 0.0049 0.0167
Mycobacterium tuberculosis Polyketide synthase Pks2 0.007 0.0313 0.2059
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0028 0.0049 0.0061
Brugia malayi RNA recognition motif domain containing protein 0.0062 0.0258 0.0321
Trypanosoma cruzi hypothetical protein, conserved 0.004 0.0127 0.1933
Loa Loa (eye worm) hypothetical protein 0.0106 0.0532 0.0661
Echinococcus granulosus neuropeptide s receptor 0.0028 0.0049 0.0061
Brugia malayi GnHR receptor homolog 0.0028 0.0049 0.0061
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0258 0.1468 1
Loa Loa (eye worm) hypothetical protein 0.0028 0.0049 0.0061
Echinococcus multilocularis carboxylesterase 5A 0.0627 0.3745 0.3745
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.008 0.0371 0.0911
Brugia malayi hypothetical protein 0.0028 0.0049 0.0061
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0026 0.004 0.009
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0106 0.0532 0.3562
Onchocerca volvulus 0.0028 0.0049 0.0167
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0028 0.0049 0.0121
Schistosoma mansoni hypothetical protein 0.0095 0.0464 0.1138
Mycobacterium tuberculosis Probable thioesterase TesA 0.0061 0.0252 0.164
Loa Loa (eye worm) hypothetical protein 0.0028 0.0049 0.0061
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0115 0.0587 0.1439
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0627 0.3745 0.9187
Loa Loa (eye worm) hypothetical protein 0.0028 0.0049 0.0061
Loa Loa (eye worm) hypothetical protein 0.0627 0.3745 0.4656
Echinococcus granulosus chromobox protein 1 0.0073 0.0331 0.0411
Plasmodium vivax hypothetical protein, conserved 0.004 0.0127 0.2637
Onchocerca volvulus 0.0028 0.0049 0.0167
Onchocerca volvulus 0.0028 0.0049 0.0167
Loa Loa (eye worm) hypothetical protein 0.0028 0.0049 0.0061
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0097 0.0478 0.0594
Schistosoma mansoni myelin transcription factor 1 myt1 0.0055 0.0215 0.0527
Trichomonas vaginalis CAMK family protein kinase 0.0049 0.0182 0.0573
Echinococcus granulosus allatostatin A receptor 0.0028 0.0049 0.0061
Echinococcus granulosus orexin receptor type 2 0.0028 0.0049 0.0061
Loa Loa (eye worm) hypothetical protein 0.0039 0.0116 0.0145
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0028 0.0049 0.0061
Loa Loa (eye worm) TAR-binding protein 0.0062 0.0258 0.0321
Mycobacterium tuberculosis Probable lipase LipD 0.004 0.0127 0.0782
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0023 0.0018 0.0018
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.004 0.0127 0.0158
Brugia malayi chromobox protein homolog 3 0.0041 0.0132 0.0164
Schistosoma mansoni BC026374 protein (S09 family) 0.0106 0.0532 0.1305
Brugia malayi G protein-coupled receptor 0.0028 0.0049 0.0061
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSB 0.0058 0.0239 0.4155
Loa Loa (eye worm) hypothetical protein 0.0028 0.0049 0.0061
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0028 0.0049 0.0061
Echinococcus granulosus serotonin receptor 0.0028 0.0049 0.0061
Echinococcus granulosus family S9 non peptidase ue S09 family 0.0106 0.0532 0.0661
Echinococcus multilocularis beta LACTamase domain containing family member 0.004 0.0127 0.0127
Brugia malayi Importin beta-1 subunit 0.0032 0.0078 0.0097
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.004 0.0127 0.0313
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0037 0.0105 0.0131
Mycobacterium tuberculosis Probable lipase LipE 0.004 0.0127 0.0782
Echinococcus multilocularis neuropeptide FF receptor 2 0.0028 0.0049 0.0049
Loa Loa (eye worm) pigment dispersing factor receptor c 0.03 0.1729 0.215
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0063 0.0266 0.0652
Echinococcus granulosus tm gpcr rhodopsin 0.0028 0.0049 0.0061
Brugia malayi Melibiase family protein 0.0077 0.0351 0.0436
Loa Loa (eye worm) hypothetical protein 0.03 0.1729 0.215
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.004 0.0127 0.0313
Echinococcus multilocularis sex peptide receptor 0.0028 0.0049 0.0049
Brugia malayi G-protein coupled receptor 0.0028 0.0049 0.0061
Schistosoma mansoni neuropeptide F-like receptor 0.0028 0.0049 0.0121
Schistosoma mansoni opsin-like receptor 0.0028 0.0049 0.0121
Mycobacterium ulcerans Type I modular polyketide synthase 0.0073 0.0327 0.2298
Echinococcus granulosus para nitrobenzyl esterase 0.0106 0.0532 0.0661
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0097 0.0478 0.1173
Toxoplasma gondii exonuclease III APE 0.0037 0.0105 0.0214
Mycobacterium ulcerans thioesterase 0.0061 0.0252 0.1745
Brugia malayi RE15519p 0.0028 0.0049 0.0061
Echinococcus granulosus rhodopsin orphan GPCR 0.0028 0.0049 0.0061
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsD 0.0073 0.0327 0.2153
Trichomonas vaginalis importin beta-1, putative 0.0026 0.004 0.009
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0155 0.0834 0.0834
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0028 0.0049 0.0121
Trypanosoma brucei hypothetical protein, conserved 0.004 0.0127 0.1198
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0115 0.0587 0.1439
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0028 0.0049 0.0121
Loa Loa (eye worm) hypothetical protein 0.0106 0.0532 0.0661
Schistosoma mansoni amine GPCR 0.0028 0.0049 0.0121
Loa Loa (eye worm) hypothetical protein 0.0041 0.0132 0.0164
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0028 0.0049 0.0049
Brugia malayi beta-lactamase family protein 0.004 0.0127 0.0158
Schistosoma mansoni hypothetical protein 0.0021 0.0006 0.0016
Echinococcus granulosus acetylcholinesterase 0.0627 0.3745 0.4656
Echinococcus multilocularis BC026374 protein (S09 family) 0.0106 0.0532 0.0532
Schistosoma mansoni hypothetical protein 0.0028 0.0049 0.0121
Mycobacterium ulcerans polyketide synthase 0.0073 0.0327 0.2298
Echinococcus multilocularis Alpha N acetylgalactosaminidase 0.0115 0.0587 0.0587
Loa Loa (eye worm) hypothetical protein 0.0041 0.013 0.0161
Brugia malayi neuropeptide F receptor 0.0028 0.0049 0.0061
Echinococcus granulosus neuropeptide FF receptor 2 0.0028 0.0049 0.0061
Mycobacterium leprae Probable lipase LipE 0.004 0.0127 0.2041
Echinococcus granulosus biogenic amine 5HT receptor 0.0028 0.0049 0.0061
Brugia malayi larval opioid receptor 0.0028 0.0049 0.0061
Echinococcus granulosus neuropeptides capa receptor 0.0028 0.0049 0.0061
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0028 0.0049 0.0049
Plasmodium vivax SET domain protein, putative 0.0063 0.0266 1
Loa Loa (eye worm) hypothetical protein 0.0028 0.0049 0.0061
Echinococcus granulosus fetal alzheimer antigen falz 0.0023 0.0018 0.0023
Brugia malayi Dopamine receptor protein 1 0.0028 0.0049 0.0061
Loa Loa (eye worm) hypothetical protein 0.0028 0.0049 0.0061
Plasmodium falciparum histone acetyltransferase GCN5 0.0041 0.0132 1
Schistosoma mansoni aldehyde dehydrogenase 0.0241 0.1368 0.3356
Trichomonas vaginalis ap endonuclease, putative 0.0037 0.0105 0.0313
Onchocerca volvulus Fatty acid synthase homolog 0.0131 0.0687 0.2327
Echinococcus granulosus rhodopsin orphan GPCR 0.0028 0.0049 0.0061
Loa Loa (eye worm) hypothetical protein 0.0028 0.0049 0.0061
Loa Loa (eye worm) hypothetical protein 0.0627 0.3745 0.4656
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0037 0.0105 0.1448
Loa Loa (eye worm) cytochrome P450 family protein 0.0028 0.0048 0.006
Mycobacterium tuberculosis Conserved protein 0.004 0.0127 0.0782
Mycobacterium tuberculosis Polyketide synthase Pks13 0.0109 0.0549 0.3677
Echinococcus multilocularis G protein coupled receptor 139 0.0028 0.0049 0.0049
Schistosoma mansoni ap endonuclease 0.0037 0.0105 0.0259
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0028 0.0049 0.0121
Loa Loa (eye worm) hypothetical protein 0.0028 0.0049 0.0061
Loa Loa (eye worm) hypothetical protein 0.0028 0.0049 0.0061
Brugia malayi Tachykinin-like peptides receptor 99D 0.0028 0.0049 0.0061
Onchocerca volvulus 0.0028 0.0049 0.0167
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0028 0.0049 0.0121
Echinococcus granulosus muscleblind protein 0.1323 0.8043 1
Loa Loa (eye worm) carboxylesterase 0.0106 0.0532 0.0661
Echinococcus granulosus chromobox protein 1 0.0073 0.0331 0.0411
Echinococcus multilocularis neuropeptides capa receptor 0.0028 0.0049 0.0049
Giardia lamblia Kinase, PLK 0.0099 0.0492 1
Schistosoma mansoni hypothetical protein 0.0028 0.0049 0.0121
Mycobacterium ulcerans polyketide synthase Pks13 0.0109 0.0549 0.3938
Echinococcus granulosus histone acetyltransferase KAT2B 0.0047 0.017 0.0211
Schistosoma mansoni biogenic amine (5HT) receptor 0.0028 0.0049 0.0121
Onchocerca volvulus 0.0028 0.0049 0.0167
Schistosoma mansoni biogenic amine receptor 0.0028 0.0049 0.0121
Brugia malayi MH2 domain containing protein 0.024 0.1357 0.1687
Brugia malayi Bromodomain containing protein 0.0079 0.0366 0.0455
Schistosoma mansoni hypothetical protein 0.0101 0.0501 0.1229
Schistosoma mansoni growth hormone secretagogue receptor 0.0028 0.0049 0.0121
Loa Loa (eye worm) fatty acid synthase 0.0072 0.0321 0.0399
Echinococcus granulosus g protein coupled receptor 0.0028 0.0049 0.0061
Brugia malayi hypothetical protein 0.0106 0.0532 0.0661
Echinococcus granulosus rhodopsin orphan GPCR 0.0028 0.0049 0.0061
Brugia malayi AMP-binding enzyme family protein 0.0068 0.0297 0.037
Onchocerca volvulus 0.0106 0.0532 0.1802
Brugia malayi Methyltransferase-like protein 4 0.0022 0.0014 0.0017
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsE 0.0048 0.0175 0.1174
Schistosoma mansoni amine GPCR 0.0028 0.0049 0.0121
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0106 0.0532 0.1305
Loa Loa (eye worm) hypothetical protein 0.0028 0.0049 0.0061
Echinococcus multilocularis chromobox protein 1 0.0073 0.0331 0.0331
Brugia malayi hypothetical protein 0.0028 0.0049 0.0061
Mycobacterium tuberculosis Polyketide synthetase MbtC (polyketide synthase) 0.0025 0.0033 0.0131
Brugia malayi putative neuropeptide receptor NPR1 0.0028 0.0049 0.0061
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0044 0.015 0.015
Trichomonas vaginalis bromodomain-containing protein, putative 0.0047 0.017 0.0532
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0075 0.034 0.0833
Echinococcus granulosus tm gpcr rhodopsin 0.0028 0.0049 0.0061
Onchocerca volvulus 0.0126 0.0659 0.2233
Trichomonas vaginalis ap endonuclease, putative 0.0037 0.0105 0.0313
Loa Loa (eye worm) hypothetical protein 0.0032 0.0078 0.0097
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0028 0.0049 0.0049
Echinococcus granulosus neuropeptides capa receptor 0.0028 0.0049 0.0061
Echinococcus multilocularis geminin 0.068 0.4076 0.4076
Mycobacterium tuberculosis Polyketide synthase Pks12 0.0077 0.0355 0.2345
Echinococcus granulosus GPCR family 2 0.0095 0.0464 0.0577
Mycobacterium ulcerans multifunctional mycocerosic acid synthase membrane-associated Mas 0.0077 0.0355 0.2504
Echinococcus multilocularis rhodopsin orphan GPCR 0.0028 0.0049 0.0049
Onchocerca volvulus 0.0028 0.0049 0.0167
Loa Loa (eye worm) hypothetical protein 0.0122 0.0632 0.0785
Trichomonas vaginalis alpha-galactosidase/alpha-N-acetylgalactosaminidase, putative 0.0077 0.0351 0.1147
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0037 0.0105 0.0632
Trypanosoma cruzi polo-like protein kinase, putative 0.0099 0.0492 1
Brugia malayi Calcitonin receptor-like protein seb-1 0.03 0.1729 0.215
Echinococcus multilocularis snurportin 1 0.0345 0.2006 0.2006
Trichomonas vaginalis CAMK family protein kinase 0.0099 0.0492 0.1627
Onchocerca volvulus 0.0106 0.0532 0.1802
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0258 0.0633
Trichomonas vaginalis D-aminoacylase, putative 0.004 0.0127 0.0387
Mycobacterium leprae Polyketide synthase Pks13 0.0109 0.0549 1
Echinococcus granulosus polycomb protein SCMH1 0.0048 0.0174 0.0216
Onchocerca volvulus 0.004 0.0127 0.0432
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0048 0.0174 0.0427
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.004 0.0127 0.0782
Echinococcus multilocularis survival motor neuron protein 1 0.0495 0.293 0.293
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0041 0.0132 0.0447
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0099 0.0492 0.3529
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0028 0.0049 0.0121
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0028 0.0049 0.0061
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0101 0.0501 0.0623
Loa Loa (eye worm) hypothetical protein 0.0106 0.0532 0.0661
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0106 0.0532 0.1305
Loa Loa (eye worm) hypothetical protein 0.004 0.0127 0.0158
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0028 0.0049 0.0121
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0028 0.0049 0.0049
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0047 0.017 0.4894
Onchocerca volvulus 0.0028 0.0049 0.0167
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0097 0.0478 0.0478
Schistosoma mansoni kinase 0.005 0.019 0.0466
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0063 0.0266 0.1457
Onchocerca volvulus 0.0028 0.0049 0.0167
Echinococcus multilocularis rhodopsin orphan GPCR 0.0028 0.0049 0.0049
Brugia malayi Beta-ketoacyl synthase, N-terminal domain containing protein 0.0073 0.0327 0.0406
Echinococcus granulosus survival motor neuron protein 1 0.0495 0.293 0.3643
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0028 0.0049 0.0121
Loa Loa (eye worm) hypothetical protein 0.0028 0.0049 0.0061
Mycobacterium tuberculosis Probable esterase LipL 0.004 0.0127 0.0782
Loa Loa (eye worm) hypothetical protein 0.0028 0.0049 0.0061
Loa Loa (eye worm) hypothetical protein 0.004 0.0127 0.0158
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0058 0.0151
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0063 0.0266 0.0266
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0099 0.0492 0.0492
Schistosoma mansoni chromobox protein 0.0073 0.0331 0.0811
Onchocerca volvulus 0.0106 0.0532 0.1802
Echinococcus multilocularis orexin receptor type 2 0.0028 0.0049 0.0049
Trichomonas vaginalis CAMK family protein kinase 0.0099 0.0492 0.1627
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0028 0.0049 0.0049
Echinococcus multilocularis neuropeptide s receptor 0.0028 0.0049 0.0049
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0055 0.0215 0.0267
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0028 0.0049 0.0061
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0037 0.0105 0.1448
Echinococcus multilocularis acetylcholinesterase 0.0627 0.3745 0.3745
Loa Loa (eye worm) hypothetical protein 0.0028 0.0049 0.0061
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0028 0.0049 0.0121
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0028 0.0049 0.0061
Echinococcus granulosus neuropeptide Y receptor 0.0028 0.0049 0.0061
Schistosoma mansoni serine/threonine protein kinase 0.0099 0.0492 0.1206
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0028 0.0049 0.0121
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0028 0.0049 0.0049
Mycobacterium tuberculosis Probable polyketide synthase Pks15 0.0029 0.006 0.0318
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0028 0.0049 0.0049
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0028 0.0049 0.0049
Echinococcus multilocularis zinc finger protein 0.0023 0.0023 0.0023
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0028 0.0049 0.0121
Trichomonas vaginalis chromobox protein, putative 0.0073 0.0331 0.1079
Brugia malayi Carboxylesterase family protein 0.0627 0.3745 0.4656
Loa Loa (eye worm) hypothetical protein 0.0071 0.0317 0.0394
Loa Loa (eye worm) hypothetical protein 0.0047 0.0166 0.0206
Echinococcus granulosus histone acetyltransferase MYST2 0.0055 0.0215 0.0267
Brugia malayi Serotonin receptor 0.0028 0.0049 0.0061
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0028 0.0049 0.0167
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.008 0.0371 0.0371
Schistosoma mansoni histamine h1 receptor 0.0028 0.0049 0.0121
Giardia lamblia Histone acetyltransferase GCN5 0.0041 0.0132 0.2479
Loa Loa (eye worm) hypothetical protein 0.0028 0.0049 0.0061
Loa Loa (eye worm) hypothetical protein 0.0028 0.0049 0.0061
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0044 0.0151 0.0512
Echinococcus granulosus histone acetyltransferase KAT2B 0.0148 0.0793 0.0986
Mycobacterium tuberculosis Polyketide synthetase MbtD (polyketide synthase) 0.0022 0.0016 0.0019
Brugia malayi sulfakinin receptor protein 0.0028 0.0049 0.0061
Mycobacterium tuberculosis Probable hydrolase 0.004 0.0127 0.0782
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0028 0.0049 0.0049
Mycobacterium leprae Probable multifunctional mycocerosic acid synthase membrane associated enzyme Mas 0.0077 0.0355 0.6337
Mycobacterium tuberculosis Probable polyketide synthase Pks8 0.0059 0.0245 0.1592
Brugia malayi Dopamine receptor 0.0028 0.0049 0.0061
Echinococcus multilocularis neuropeptide Y receptor 0.0028 0.0049 0.0049
Brugia malayi acetyltransferase, GNAT family protein 0.0155 0.0834 0.1037
Onchocerca volvulus 0.0028 0.0049 0.0167
Schistosoma mansoni hypothetical protein 0.068 0.4076 1
Schistosoma mansoni neuropeptide receptor 0.0028 0.0049 0.0121
Echinococcus granulosus g-protein coupled receptor 0.0028 0.0049 0.0061
Loa Loa (eye worm) latrophilin receptor protein 2 0.0095 0.0464 0.0577
Brugia malayi mbt repeat family protein 0.0048 0.0174 0.0216
Mycobacterium leprae conserved hypothetical protein 0.004 0.0127 0.2041
Brugia malayi AMP-binding enzyme family protein 0.0022 0.0016 0.002
Loa Loa (eye worm) transcription factor SMAD2 0.024 0.1357 0.1687
Loa Loa (eye worm) hypothetical protein 0.0028 0.0049 0.0061
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0037 0.0105 0.0105
Echinococcus granulosus rhodopsin orphan GPCR 0.0028 0.0049 0.0061
Onchocerca volvulus 0.004 0.0127 0.0432
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0097 0.0478 0.0594
Brugia malayi TAR-binding protein 0.0062 0.0258 0.0321
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0037 0.0105 0.5
Loa Loa (eye worm) hypothetical protein 0.0028 0.0049 0.0061
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsC 0.0077 0.0355 0.2504
Schistosoma mansoni neuropeptide F-like receptor 0.0028 0.0049 0.0121
Schistosoma mansoni methyltransferase-related 0.0022 0.0014 0.0033
Loa Loa (eye worm) hypothetical protein 0.0028 0.0049 0.0061
Echinococcus granulosus neuropeptide receptor 0.0028 0.0049 0.0061
Brugia malayi PHD-finger family protein 0.0029 0.0056 0.007
Loa Loa (eye worm) hypothetical protein 0.0095 0.0464 0.0577
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0028 0.0049 0.0121
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0028 0.0049 0.0121
Echinococcus multilocularis somatostatin receptor 0.0028 0.0049 0.0049
Echinococcus granulosus rhodopsin orphan GPCR 0.0028 0.0049 0.0061
Brugia malayi latrophilin 2 splice variant baaae 0.0205 0.1144 0.1422
Schistosoma mansoni opsin-like receptor 0.0028 0.0049 0.0121
Brugia malayi hypothetical protein 0.0028 0.0049 0.0061
Loa Loa (eye worm) acetylcholinesterase 1 0.0627 0.3745 0.4656
Echinococcus multilocularis dro:myosuppressin receptor 0.0028 0.0049 0.0049
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0028 0.0049 0.0121
Onchocerca volvulus 0.0032 0.0077 0.0262
Trichomonas vaginalis D-aminoacylase, putative 0.004 0.0127 0.0387
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsA 0.0058 0.0239 0.1649
Onchocerca volvulus Serine\/threonine kinase homolog 0.0099 0.0492 0.1666
Schistosoma mansoni hypothetical protein 0.0299 0.1721 0.4221
Brugia malayi exodeoxyribonuclease III family protein 0.0037 0.0105 0.0131
Echinococcus granulosus snurportin 1 0.0345 0.2006 0.2494
Brugia malayi hypothetical protein 0.0028 0.0049 0.0061
Brugia malayi beta-lactamase 0.004 0.0127 0.0158
Mycobacterium ulcerans fatty acid synthase Fas 0.0023 0.0019 0.0022
Trichomonas vaginalis spcc417.12 protein, putative 0.0106 0.0532 0.1764
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0028 0.0049 0.0049
Onchocerca volvulus Neuropeptide F receptor homolog 0.0028 0.0049 0.0167
Loa Loa (eye worm) MBCTL1 0.0055 0.0215 0.0267
Brugia malayi G-protein coupled receptor 0.0028 0.0049 0.0061
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0077 0.0351 0.086
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0097 0.0478 0.0594
Echinococcus multilocularis rhodopsin orphan GPCR 0.0028 0.0049 0.0049
Loa Loa (eye worm) hypothetical protein 0.0028 0.0049 0.0061
Echinococcus multilocularis g protein coupled receptor 0.0028 0.0049 0.0049
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0095 0.0464 0.0577
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0023 0.0018 0.0045
Echinococcus granulosus zinc finger protein 0.0023 0.0023 0.0028
Echinococcus multilocularis importin subunit beta 1 0.0032 0.0078 0.0078
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0055 0.0215 0.0267
Echinococcus multilocularis serotonin receptor 0.0028 0.0049 0.0049
Brugia malayi neuropeptide F receptor 0.0028 0.0049 0.0061
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.008 0.0371 0.0911
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0058 0.0151
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0438 0.2578 0.3205
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0047 0.017 0.0713
Brugia malayi hypothetical protein 0.0028 0.0049 0.0061
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0241 0.1368 0.1701
Schistosoma mansoni zinc finger protein 0.0023 0.0023 0.0056
Loa Loa (eye worm) hypothetical protein 0.0028 0.0049 0.0061
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0028 0.0049 0.0061
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0028 0.0049 0.0121
Schistosoma mansoni hypothetical protein 0.0028 0.0049 0.0121
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0028 0.0049 0.0121
Brugia malayi Muscleblind-like protein 0.1323 0.8043 1
Loa Loa (eye worm) melatonin receptor type 1A 0.0028 0.0049 0.0061
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0037 0.0105 0.0131
Echinococcus granulosus 7TM GPCR rhodopsin 0.0028 0.0049 0.0061
Echinococcus granulosus fmrfamide receptor 0.0028 0.0049 0.0061
Loa Loa (eye worm) mbt repeat family protein 0.0048 0.0174 0.0216
Loa Loa (eye worm) hypothetical protein 0.0028 0.0049 0.0061
Echinococcus granulosus tachykinin peptides receptor 99D 0.0028 0.0049 0.0061
Loa Loa (eye worm) hypothetical protein 0.0028 0.0049 0.0061
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0048 0.0174 0.059
Schistosoma mansoni hypothetical protein 0.0205 0.1144 0.2805
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0037 0.0105 0.1471
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0132 0.0403
Loa Loa (eye worm) hypothetical protein 0.0028 0.0049 0.0061
Loa Loa (eye worm) hypothetical protein 0.1323 0.8043 1
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0095 0.0464 0.0464
Schistosoma mansoni aldehyde dehydrogenase 0.0241 0.1368 0.3356
Brugia malayi Cytochrome P450 family protein 0.0028 0.0048 0.006
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSD 0.0073 0.0327 0.581
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0028 0.0049 0.0121
Entamoeba histolytica acetyltransferase, GNAT family 0.0041 0.0132 0.2037
Echinococcus granulosus tm gpcr rhodopsin 0.0028 0.0049 0.0061
Echinococcus granulosus importin subunit beta 1 0.0032 0.0078 0.0097
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0068 0.0297 0.1951
Loa Loa (eye worm) hypothetical protein 0.0048 0.0174 0.0216
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0196 0.1089 0.1354
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0028 0.0049 0.0049
Loa Loa (eye worm) TYRA-2 protein 0.0028 0.0049 0.0061
Brugia malayi serine/threonine-protein kinase plk-2 0.0099 0.0492 0.0611
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.004 0.0127 0.0782
Echinococcus granulosus alpha 1A adrenergic receptor 0.0028 0.0049 0.0061
Brugia malayi RNA, U transporter 1 0.0092 0.0445 0.0554
Schistosoma mansoni sex comb on midleg homolog 0.0048 0.0174 0.0427
Trichomonas vaginalis chromobox protein, putative 0.0073 0.0331 0.1079
Schistosoma mansoni neuropeptide receptor 0.0028 0.0049 0.0121
Onchocerca volvulus 0.0075 0.034 0.1151
Loa Loa (eye worm) hypothetical protein 0.0028 0.0049 0.0061
Schistosoma mansoni hypothetical protein 0.0345 0.2006 0.4922
Trichomonas vaginalis set domain proteins, putative 0.0498 0.2951 1
Brugia malayi Heterochromatin protein 1 0.0073 0.0331 0.0411
Echinococcus multilocularis G-protein coupled receptor, putative 0.0028 0.0049 0.0049
Brugia malayi Carboxylesterase family protein 0.0106 0.0532 0.0661
Mycobacterium ulcerans lipase LipD 0.004 0.0127 0.0821
Echinococcus granulosus neuropeptide receptor 0.0028 0.0049 0.0061
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0097 0.0478 0.1173
Loa Loa (eye worm) hypothetical protein 0.0028 0.0049 0.0061
Onchocerca volvulus 0.004 0.0127 0.0432
Mycobacterium tuberculosis Probable polyketide synthase Pks5 0.007 0.0313 0.2059
Echinococcus granulosus biogenic amine 5HT receptor 0.0028 0.0049 0.0061
Schistosoma mansoni amine GPCR 0.0028 0.0049 0.0121
Loa Loa (eye worm) MH2 domain-containing protein 0.024 0.1357 0.1687
Loa Loa (eye worm) bromodomain containing protein 0.0021 0.0011 0.0014
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0241 0.1368 0.9308
Brugia malayi RNA binding protein 0.0062 0.0258 0.0321
Schistosoma mansoni neuropeptide f receptor 76f 0.0028 0.0049 0.0121
Brugia malayi putative neuropeptide receptor 0.0028 0.0049 0.0061
Mycobacterium tuberculosis Carboxylesterase LipT 0.0106 0.0532 0.3562
Onchocerca volvulus 0.0101 0.0501 0.1697
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0258 0.0633
Mycobacterium ulcerans hypothetical protein 0.004 0.0127 0.0821
Schistosoma mansoni myosin xvIII 0.0028 0.0049 0.0121
Schistosoma mansoni hypothetical protein 0.0095 0.0464 0.1138
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0028 0.0049 0.0061
Echinococcus granulosus hypothetical protein 0.0028 0.0049 0.0061
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSE 0.0048 0.0175 0.2941
Loa Loa (eye worm) hypothetical protein 0.0028 0.0049 0.0061
Echinococcus granulosus neuropeptide Y receptor 0.0028 0.0049 0.0061
Loa Loa (eye worm) hypothetical protein 0.004 0.0127 0.0158
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0037 0.0105 0.1923
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0258 0.0633
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0036 0.0101 0.0126
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0028 0.0049 0.0121
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0099 0.0492 0.0611
Trichomonas vaginalis CAMK family protein kinase 0.0099 0.0492 0.1627
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0028 0.0049 0.0049
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0028 0.0049 0.0121
Echinococcus granulosus beta LACTamase domain containing family member 0.004 0.0127 0.0158
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0106 0.0532 0.3562
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0062 0.0258 0.0321
Trichomonas vaginalis chromobox protein, putative 0.0044 0.0151 0.0468
Schistosoma mansoni biogenic amine receptor 0.0028 0.0049 0.0121
Leishmania major hypothetical protein, conserved 0.004 0.0127 0.084
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0028 0.0049 0.0049
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0028 0.0049 0.0061
Echinococcus granulosus peptide allatostatin:somatostatin 0.0028 0.0049 0.0061
Loa Loa (eye worm) hypothetical protein 0.0028 0.0049 0.0061
Schistosoma mansoni lipoxygenase 0.0044 0.015 0.0367
Brugia malayi Carboxylesterase family protein 0.0106 0.0532 0.0661
Loa Loa (eye worm) carboxylesterase 0.0627 0.3745 0.4656
Echinococcus multilocularis serotonin receptor 0.0028 0.0049 0.0049
Trichomonas vaginalis CAMK family protein kinase 0.0099 0.0492 0.1627
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0026 0.004 0.009
Echinococcus multilocularis g-protein coupled receptor 0.0028 0.0049 0.0049
Loa Loa (eye worm) PHD-finger family protein 0.0021 0.0006 0.0008
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.03 0.1729 0.215
Leishmania major importin beta-1 subunit, putative 0.0026 0.004 0.0196
Trichomonas vaginalis esterase, putative 0.004 0.0127 0.0387
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0028 0.0049 0.0061
Mycobacterium tuberculosis Probable polyketide synthase Pks9 0.0041 0.0133 0.0824
Mycobacterium tuberculosis Probable conserved lipoprotein 0.004 0.0127 0.0782
Loa Loa (eye worm) acyl carrier protein 0.0033 0.0085 0.0105
Echinococcus granulosus tar DNA binding protein 0.0062 0.0258 0.0321
Onchocerca volvulus 0.0498 0.2951 1
Echinococcus multilocularis g protein coupled receptor 0.0028 0.0049 0.0049
Loa Loa (eye worm) hypothetical protein 0.0055 0.0215 0.0267
Brugia malayi Latrophilin receptor protein 2 0.0095 0.0464 0.0577
Schistosoma mansoni sex comb on midleg homolog 0.0048 0.0174 0.0427
Trichomonas vaginalis penicillin-binding protein, putative 0.004 0.0127 0.0387
Mycobacterium ulcerans Type I modular polyketide synthase 0.0073 0.0327 0.2298
Echinococcus multilocularis allatostatin A receptor 0.0028 0.0049 0.0049
Echinococcus granulosus rhodopsin orphan GPCR 0.0028 0.0049 0.0061
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSC 0.0077 0.0355 0.6337
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsD 0.0073 0.0327 0.2298
Echinococcus multilocularis g protein coupled receptor 0.0028 0.0049 0.0049
Trichomonas vaginalis CAMK family protein kinase 0.0099 0.0492 0.1627
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0258 0.0633
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0132 0.0403
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0028 0.0049 0.0061
Treponema pallidum exodeoxyribonuclease (exoA) 0.0037 0.0105 0.5
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0196 0.1089 0.1089
Schistosoma mansoni bromodomain containing protein 0.0067 0.0294 0.072
Echinococcus granulosus rhodopsin orphan GPCR 0.0028 0.0049 0.0061
Onchocerca volvulus 0.0028 0.0049 0.0167
Loa Loa (eye worm) hypothetical protein 0.0028 0.0049 0.0061
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0028 0.0049 0.0121
Brugia malayi follicle stimulating hormone receptor 0.0028 0.0049 0.0061
Loa Loa (eye worm) hypothetical protein 0.0205 0.1144 0.1422
Onchocerca volvulus 0.0028 0.0049 0.0167
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0028 0.0049 0.0061
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0037 0.0105 0.1448
Loa Loa (eye worm) hypothetical protein 0.0028 0.0049 0.0061
Trypanosoma cruzi polo-like protein kinase, putative 0.0099 0.0492 1
Trichomonas vaginalis penicillin-binding protein, putative 0.004 0.0127 0.0387
Trichomonas vaginalis carboxylesterase domain containing protein, putative 0.0106 0.0532 0.1764
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsB 0.0058 0.0239 0.1649
Loa Loa (eye worm) neuropeptide F receptor 0.0028 0.0049 0.0061
Schistosoma mansoni alpha-1 adrenergic receptor 0.0028 0.0049 0.0121
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0037 0.0105 0.0679
Mycobacterium ulcerans carboxylesterase, LipT 0.0106 0.0532 0.3814
Schistosoma mansoni hypothetical protein 0.0028 0.0049 0.0121
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0028 0.0049 0.0061
Echinococcus granulosus geminin 0.068 0.4076 0.5068
Toxoplasma gondii ABC1 family protein 0.004 0.0127 0.0384
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0097 0.0478 0.0478
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0095 0.0464 0.0464
Trichomonas vaginalis D-aminoacylase, putative 0.004 0.0127 0.0387
Schistosoma mansoni adenoreceptor 0.0028 0.0049 0.0121
Mycobacterium tuberculosis Conserved protein 0.004 0.0127 0.0782
Echinococcus multilocularis rhodopsin orphan GPCR 0.0028 0.0049 0.0049
Mycobacterium leprae Probable polyketide synthase Pks1 0.0077 0.0355 0.6337
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.004 0.0127 0.0158
Brugia malayi Melatonin receptor type 1A 0.0028 0.0049 0.0061
Trichomonas vaginalis CAMK family protein kinase 0.0099 0.0492 0.1627
Schistosoma mansoni acetylcholinesterase 0.0106 0.0532 0.1305
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0115 0.0587 0.1439
Mycobacterium ulcerans aldehyde dehydrogenase 0.0241 0.1368 1
Brugia malayi Pre-SET motif family protein 0.0063 0.0266 0.033
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0037 0.0105 0.0659
Mycobacterium leprae PROBABLE THIOESTERASE TESA 0.0061 0.0252 0.4398
Echinococcus multilocularis tar DNA binding protein 0.0062 0.0258 0.0258
Onchocerca volvulus 0.0048 0.0174 0.059
Echinococcus multilocularis SAM and MBT domain containing protein 0.0048 0.0174 0.0174
Loa Loa (eye worm) hypothetical protein 0.0028 0.0049 0.0061
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0241 0.1368 0.1368

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

If you have references for this compound, please enter them in a user comment (below) or Contact us.