Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.0073 | 0.0442 | 0.0638 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0274 | 0.1916 | 0.1916 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0051 | 0.0285 | 0.2539 |
Echinococcus granulosus | acetylcholinesterase | 0.0957 | 0.6929 | 0.6929 |
Brugia malayi | MH2 domain containing protein | 0.0118 | 0.0776 | 0.1106 |
Mycobacterium tuberculosis | Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB | 0.0364 | 0.2577 | 0.7745 |
Echinococcus multilocularis | lamin | 0.0026 | 0.01 | 0.01 |
Mycobacterium tuberculosis | Probable esterase/lipase LipP | 0.0073 | 0.0442 | 0.1291 |
Loa Loa (eye worm) | hypothetical protein | 0.0091 | 0.0573 | 0.0827 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0073 | 0.0442 | 0.0428 |
Brugia malayi | alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase | 0.0041 | 0.0205 | 0.0282 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0051 | 0.0285 | 0.2202 |
Schistosoma mansoni | tar DNA-binding protein | 0.0065 | 0.0384 | 0.037 |
Schistosoma mansoni | glutaminase | 0.0288 | 0.2017 | 0.2005 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0051 | 0.0285 | 0.2539 |
Brugia malayi | Pre-SET motif family protein | 0.0091 | 0.0573 | 0.0813 |
Leishmania major | dihydrolipoamide dehydrogenase, putative | 0.0055 | 0.0313 | 0.2431 |
Schistosoma mansoni | gliotactin | 0.0162 | 0.1093 | 0.108 |
Leishmania major | dihydrolipoamide dehydrogenase, putative | 0.0055 | 0.0313 | 0.2431 |
Echinococcus granulosus | aryl hydrocarbon receptor | 0.0026 | 0.0095 | 0.0095 |
Loa Loa (eye worm) | carboxylesterase | 0.0162 | 0.1093 | 0.1578 |
Onchocerca volvulus | 0.0073 | 0.0444 | 0.0834 | |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0051 | 0.0285 | 0.2539 |
Echinococcus granulosus | pyridine nucleotide disulfide oxidoreductase | 0.0015 | 0.0015 | 0.0015 |
Brugia malayi | hypothetical protein | 0.0107 | 0.0692 | 0.0986 |
Schistosoma mansoni | single-minded | 0.0099 | 0.0632 | 0.0618 |
Mycobacterium leprae | Possible regulatory protein | 0.0026 | 0.0095 | 0.0282 |
Trypanosoma cruzi | cytochrome P450, putative | 0.0019 | 0.005 | 0.0332 |
Toxoplasma gondii | NADPH-glutathione reductase | 0.0055 | 0.0313 | 0.2431 |
Loa Loa (eye worm) | hypothetical protein | 0.0162 | 0.1093 | 0.1578 |
Plasmodium falciparum | thioredoxin reductase | 0.0055 | 0.0313 | 0.2803 |
Brugia malayi | Apoptosis regulator proteins, Bcl-2 family protein | 0.0084 | 0.0523 | 0.0741 |
Trichomonas vaginalis | set domain proteins, putative | 0.0716 | 0.5158 | 1 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0055 | 0.0313 | 0.2803 |
Treponema pallidum | NADH oxidase | 0.0055 | 0.0313 | 1 |
Loa Loa (eye worm) | intermediate filament protein | 0.0026 | 0.01 | 0.0144 |
Echinococcus granulosus | geminin | 0.0662 | 0.4767 | 0.4767 |
Echinococcus granulosus | cpg binding protein | 0.0032 | 0.0141 | 0.0141 |
Schistosoma mansoni | neuroligin 3 (S09 family) | 0.0162 | 0.1093 | 0.108 |
Echinococcus multilocularis | para nitrobenzyl esterase | 0.0162 | 0.1093 | 0.1093 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0162 | 0.1093 | 0.108 |
Brugia malayi | hypothetical protein | 0.0051 | 0.0285 | 0.0397 |
Echinococcus multilocularis | family S9 non peptidase ue (S09 family) | 0.0162 | 0.1093 | 0.1093 |
Schistosoma mansoni | cpg binding protein | 0.003 | 0.0129 | 0.0114 |
Schistosoma mansoni | ferritin | 0.0017 | 0.0032 | 0.0017 |
Loa Loa (eye worm) | hypothetical protein | 0.0162 | 0.1093 | 0.1578 |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.0087 | 0.0544 | 0.0544 |
Schistosoma mansoni | microtubule-associated protein tau | 0.1375 | 1 | 1 |
Brugia malayi | beta-lactamase | 0.0073 | 0.0442 | 0.0624 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0118 | 0.0776 | 0.112 |
Loa Loa (eye worm) | hypothetical protein | 0.0073 | 0.0442 | 0.0638 |
Loa Loa (eye worm) | hypoxia-induced factor 1 | 0.0306 | 0.2151 | 0.3105 |
Trichomonas vaginalis | soluble guanylate cyclase gcy, putative | 0.0026 | 0.0095 | 0.0157 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0073 | 0.0442 | 0.083 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0073 | 0.0442 | 0.0442 |
Mycobacterium ulcerans | bacterioferritin BfrB | 0.0017 | 0.0032 | 0.0086 |
Schistosoma mansoni | ferritin | 0.0017 | 0.0032 | 0.0017 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0162 | 0.1093 | 0.108 |
Onchocerca volvulus | 0.0162 | 0.1093 | 0.2097 | |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0182 | 0.1241 | 0.1228 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0051 | 0.0285 | 0.2539 |
Treponema pallidum | bacterioferrin (TpF1) | 0.0017 | 0.0032 | 0.0576 |
Loa Loa (eye worm) | hypothetical protein | 0.0331 | 0.234 | 0.3377 |
Giardia lamblia | NADH oxidase lateral transfer candidate | 0.0055 | 0.0313 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0162 | 0.1093 | 0.1578 |
Echinococcus granulosus | dihydropyrimidine dehydrogenase NADP | 0.0015 | 0.0015 | 0.0015 |
Mycobacterium ulcerans | carboxylesterase, LipT | 0.0162 | 0.1093 | 0.5387 |
Leishmania major | protein kinase, putative | 0.0026 | 0.0095 | 0.0659 |
Brugia malayi | Pyridine nucleotide-disulphide oxidoreductase family protein | 0.0015 | 0.0015 | 0.0006 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0073 | 0.0442 | 0.083 |
Echinococcus multilocularis | lamin dm0 | 0.0026 | 0.01 | 0.01 |
Mycobacterium tuberculosis | Carboxylesterase LipT | 0.0162 | 0.1093 | 0.3261 |
Echinococcus multilocularis | ferritin | 0.0017 | 0.0032 | 0.0032 |
Schistosoma mansoni | hypothetical protein | 0.0084 | 0.0523 | 0.0509 |
Trypanosoma cruzi | STE group serine/threonine-protein kinase, putative | 0.0026 | 0.0095 | 0.076 |
Entamoeba histolytica | hypothetical protein | 0.0107 | 0.0692 | 1 |
Schistosoma mansoni | dihydrolipoamide dehydrogenase | 0.0055 | 0.0313 | 0.0298 |
Mycobacterium tuberculosis | NADPH-dependent mycothiol reductase Mtr | 0.0159 | 0.1078 | 0.3213 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0019 | 0.005 | 0.0072 |
Trypanosoma cruzi | cytochrome P450, putative | 0.0019 | 0.005 | 0.0332 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0095 | 0.0138 |
Echinococcus granulosus | lamin dm0 | 0.0026 | 0.01 | 0.01 |
Mycobacterium leprae | DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE | 0.0404 | 0.2875 | 1 |
Trichomonas vaginalis | guanylate cyclase, putative | 0.0026 | 0.0095 | 0.0157 |
Toxoplasma gondii | thioredoxin reductase | 0.0159 | 0.1078 | 0.8671 |
Echinococcus granulosus | Bcl 2 ous antagonist:killer | 0.0084 | 0.0523 | 0.0523 |
Schistosoma mansoni | hypothetical protein | 0.043 | 0.3064 | 0.3054 |
Trichomonas vaginalis | adenylate cyclase, putative | 0.0026 | 0.0095 | 0.0157 |
Brugia malayi | PAS domain containing protein | 0.0099 | 0.0632 | 0.0899 |
Echinococcus multilocularis | aryl hydrocarbon receptor | 0.0026 | 0.0095 | 0.0095 |
Mycobacterium tuberculosis | Conserved protein | 0.0073 | 0.0442 | 0.1291 |
Echinococcus multilocularis | cpg binding protein | 0.0032 | 0.0141 | 0.0141 |
Trypanosoma cruzi | STE group serine/threonine-protein kinase, putative | 0.0026 | 0.0095 | 0.076 |
Mycobacterium tuberculosis | Probable esterase LipL | 0.0073 | 0.0442 | 0.1291 |
Mycobacterium tuberculosis | Probable conserved lipoprotein | 0.0073 | 0.0442 | 0.1291 |
Echinococcus granulosus | Ataxin 2 N terminaldomain containing protein | 0.0023 | 0.0076 | 0.0076 |
Brugia malayi | Carboxylesterase family protein | 0.0957 | 0.6929 | 1 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0055 | 0.0313 | 0.2803 |
Chlamydia trachomatis | two component regulatory system sensor histidine kinase | 0.0026 | 0.0095 | 0.2711 |
Loa Loa (eye worm) | hypothetical protein | 0.0957 | 0.6929 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0662 | 0.4767 | 0.4759 |
Onchocerca volvulus | 0.0073 | 0.0442 | 0.083 | |
Trichomonas vaginalis | conserved hypothetical protein | 0.0026 | 0.0095 | 0.0157 |
Schistosoma mansoni | hypothetical protein | 0.0107 | 0.0692 | 0.0679 |
Mycobacterium ulcerans | dihydrolipoamide dehydrogenase | 0.0055 | 0.0313 | 0.1488 |
Trichomonas vaginalis | spcc417.12 protein, putative | 0.0162 | 0.1093 | 0.2097 |
Loa Loa (eye worm) | carboxylesterase | 0.0162 | 0.1093 | 0.1578 |
Loa Loa (eye worm) | carboxylesterase | 0.0957 | 0.6929 | 1 |
Onchocerca volvulus | 0.0026 | 0.0095 | 0.0157 | |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.0091 | 0.0573 | 0.0559 |
Toxoplasma gondii | pyruvate dehydrogenase complex subunit PDH-E3II | 0.0055 | 0.0313 | 0.2431 |
Echinococcus multilocularis | transfer RNA-Lys | 0.0073 | 0.0444 | 0.0444 |
Echinococcus multilocularis | neuroligin | 0.0162 | 0.1093 | 0.1093 |
Echinococcus multilocularis | glutamate synthase | 0.0015 | 0.0015 | 0.0015 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0055 | 0.0313 | 0.2803 |
Echinococcus granulosus | glutamate synthase | 0.0015 | 0.0015 | 0.0015 |
Onchocerca volvulus | 0.0162 | 0.1093 | 0.2097 | |
Echinococcus granulosus | NADPH:adrenodoxin oxidoreductase | 0.0015 | 0.0015 | 0.0015 |
Onchocerca volvulus | 0.0162 | 0.1093 | 0.2097 | |
Schistosoma mansoni | BC026374 protein (S09 family) | 0.0162 | 0.1093 | 0.108 |
Wolbachia endosymbiont of Brugia malayi | dihydrolipoamide dehydrogenase E3 component | 0.0055 | 0.0313 | 1 |
Mycobacterium tuberculosis | Probable NADH dehydrogenase Ndh | 0.0364 | 0.2577 | 0.7745 |
Schistosoma mansoni | hypothetical protein | 0.0662 | 0.4767 | 0.4759 |
Schistosoma mansoni | ferritin light chain | 0.0017 | 0.0032 | 0.0017 |
Plasmodium vivax | dihydrolipoyl dehydrogenase, mitochondrial, putative | 0.0055 | 0.0313 | 0.2803 |
Loa Loa (eye worm) | aryl Hydrocarbon receptor Associated protein family member | 0.0026 | 0.0095 | 0.0138 |
Trichomonas vaginalis | adenylate cyclase, type VII, putative | 0.0026 | 0.0095 | 0.0157 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0055 | 0.0313 | 0.2803 |
Brugia malayi | Pyridine nucleotide-disulphide oxidoreductase family protein | 0.0015 | 0.0015 | 0.0006 |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.0061 | 0.0351 | 0.2746 |
Schistosoma mansoni | ferritin light chain | 0.0017 | 0.0032 | 0.0017 |
Trypanosoma brucei | cytochrome P450, putative | 0.0019 | 0.005 | 0.0332 |
Leishmania major | acetoin dehydrogenase e3 component-like protein | 0.0055 | 0.0313 | 0.2431 |
Brugia malayi | Carboxylesterase family protein | 0.0162 | 0.1093 | 0.1566 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0091 | 0.0573 | 0.0559 |
Echinococcus granulosus | dihydropyrimidine dehydrogenase NADP | 0.0015 | 0.0015 | 0.0015 |
Brugia malayi | Carboxylesterase family protein | 0.0162 | 0.1093 | 0.1566 |
Leishmania major | hypothetical protein, conserved | 0.0073 | 0.0442 | 0.3483 |
Echinococcus multilocularis | dnaJ subfamily B | 0.043 | 0.3064 | 0.3064 |
Echinococcus multilocularis | dihydropyrimidine dehydrogenase (NADP+) | 0.0015 | 0.0015 | 0.0015 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0107 | 0.0692 | 0.0692 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.0465 | 0.3323 | 1 |
Loa Loa (eye worm) | apoptosis regulator protein | 0.0084 | 0.0523 | 0.0755 |
Schistosoma mansoni | tar DNA-binding protein | 0.0065 | 0.0384 | 0.037 |
Echinococcus granulosus | sulfide:quinone oxidoreductase | 0.0015 | 0.0015 | 0.0015 |
Echinococcus multilocularis | aldehyde dehydrogenase, mitochondrial | 0.0182 | 0.1241 | 0.1241 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0026 | 0.0095 | 0.0157 |
Brugia malayi | RNA binding protein | 0.0065 | 0.0384 | 0.0541 |
Trichomonas vaginalis | glutaminase, putative | 0.0288 | 0.2017 | 0.3893 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0026 | 0.0095 | 0.0157 |
Plasmodium vivax | thioredoxin reductase, putative | 0.0159 | 0.1078 | 1 |
Mycobacterium leprae | PROBABLE NADH DEHYDROGENASE NDH | 0.0364 | 0.2577 | 0.8958 |
Echinococcus multilocularis | pyridine nucleotide disulfide oxidoreductase | 0.0015 | 0.0015 | 0.0015 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.01 | 0.0144 |
Echinococcus granulosus | carboxylesterase 5A | 0.0957 | 0.6929 | 0.6929 |
Mycobacterium ulcerans | dihydrolipoamide dehydrogenase, LpdB | 0.0055 | 0.0313 | 0.1488 |
Loa Loa (eye worm) | hypothetical protein | 0.0162 | 0.1093 | 0.1578 |
Loa Loa (eye worm) | hypothetical protein | 0.0957 | 0.6929 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0162 | 0.1093 | 0.1578 |
Echinococcus granulosus | neuropeptide receptor A26 | 0.0456 | 0.3254 | 0.3254 |
Echinococcus multilocularis | acetylcholinesterase | 0.0957 | 0.6929 | 0.6929 |
Echinococcus multilocularis | dihydropyrimidine dehydrogenase (NADP+) | 0.0015 | 0.0015 | 0.0015 |
Echinococcus multilocularis | NADPH:adrenodoxin oxidoreductase | 0.0015 | 0.0015 | 0.0015 |
Echinococcus multilocularis | carboxylesterase 5A | 0.0957 | 0.6929 | 0.6929 |
Schistosoma mansoni | cpg binding protein | 0.0032 | 0.0141 | 0.0127 |
Leishmania major | hypothetical protein, conserved | 0.0051 | 0.0285 | 0.2202 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.0957 | 0.6929 | 1 |
Loa Loa (eye worm) | glutathione reductase | 0.0159 | 0.1078 | 0.1555 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0182 | 0.1241 | 0.6122 |
Onchocerca volvulus | 0.0716 | 0.5158 | 1 | |
Chlamydia trachomatis | dihydrolipoyl dehydrogenase | 0.0055 | 0.0313 | 1 |
Echinococcus granulosus | lamin | 0.0026 | 0.01 | 0.01 |
Mycobacterium tuberculosis | Probable dehydrogenase | 0.0364 | 0.2577 | 0.7745 |
Trypanosoma cruzi | PAS-domain containing phosphoglycerate kinase, putative | 0.0026 | 0.0095 | 0.076 |
Brugia malayi | Cytochrome P450 family protein | 0.0049 | 0.0267 | 0.0371 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0182 | 0.1241 | 0.1228 |
Mycobacterium tuberculosis | Possible conserved lipoprotein LpqK | 0.0073 | 0.0442 | 0.1291 |
Onchocerca volvulus | 0.0026 | 0.01 | 0.0165 | |
Mycobacterium ulcerans | glutaminase | 0.0288 | 0.2017 | 1 |
Mycobacterium ulcerans | flavoprotein disulfide reductase | 0.0055 | 0.0313 | 0.1488 |
Mycobacterium tuberculosis | Probable aldehyde dehydrogenase | 0.0182 | 0.1241 | 0.3705 |
Echinococcus granulosus | family S9 non peptidase ue S09 family | 0.0162 | 0.1093 | 0.1093 |
Echinococcus granulosus | dnaJ subfamily B | 0.043 | 0.3064 | 0.3064 |
Brugia malayi | Thioredoxin reductase | 0.0159 | 0.1078 | 0.1543 |
Brugia malayi | hypothetical protein | 0.0033 | 0.0151 | 0.0203 |
Echinococcus multilocularis | Aryl hydrocarbon receptor nuclear | 0.0026 | 0.0095 | 0.0095 |
Mycobacterium leprae | Probable lipase LipE | 0.0073 | 0.0442 | 0.1493 |
Echinococcus granulosus | ferritin | 0.0017 | 0.0032 | 0.0032 |
Trypanosoma cruzi | STE/STE11 serine/threonine-protein kinase, putative | 0.0026 | 0.0095 | 0.076 |
Echinococcus multilocularis | Ataxin 2, N terminal,domain containing protein | 0.0023 | 0.0076 | 0.0076 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0073 | 0.0442 | 0.4018 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0073 | 0.0442 | 0.0428 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0055 | 0.0313 | 0.2803 |
Brugia malayi | Carboxylesterase family protein | 0.0957 | 0.6929 | 1 |
Onchocerca volvulus | 0.0162 | 0.1093 | 0.2097 | |
Echinococcus multilocularis | EGFP:Bcl2 fusion protein | 0.0084 | 0.0523 | 0.0523 |
Mycobacterium tuberculosis | Putative ferredoxin reductase | 0.0364 | 0.2577 | 0.7745 |
Schistosoma mansoni | apoptosis regulator bax | 0.0084 | 0.0523 | 0.0509 |
Leishmania major | cytochrome p450-like protein | 0.0019 | 0.005 | 0.0288 |
Schistosoma mansoni | bcl-2 homologous antagonist/killer (bak) | 0.0084 | 0.0523 | 0.0509 |
Plasmodium falciparum | glutathione reductase | 0.0159 | 0.1078 | 1 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0073 | 0.0442 | 0.0624 |
Mycobacterium ulcerans | esterase/lipase LipP | 0.0073 | 0.0442 | 0.2133 |
Mycobacterium ulcerans | hypothetical protein | 0.0073 | 0.0442 | 0.2133 |
Loa Loa (eye worm) | hypothetical protein | 0.0073 | 0.0442 | 0.0638 |
Brugia malayi | Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein | 0.0041 | 0.0205 | 0.0282 |
Brugia malayi | bHLH-PAS transcription factor | 0.0073 | 0.0444 | 0.0627 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.003 | 0.0129 | 0.0186 |
Trichomonas vaginalis | ferritin, putative | 0.0017 | 0.0032 | 0.0033 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0274 | 0.1916 | 0.1916 |
Mycobacterium tuberculosis | Conserved protein | 0.0073 | 0.0442 | 0.1291 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0055 | 0.0313 | 0.2803 |
Brugia malayi | Carboxylesterase family protein | 0.0162 | 0.1093 | 0.1566 |
Trypanosoma cruzi | STE/STE11 serine/threonine-protein kinase, putative | 0.0026 | 0.0095 | 0.076 |
Trichomonas vaginalis | guanylate cyclase, putative | 0.0026 | 0.0095 | 0.0157 |
Brugia malayi | CXXC zinc finger family protein | 0.003 | 0.0129 | 0.0171 |
Loa Loa (eye worm) | hypothetical protein | 0.0073 | 0.0442 | 0.0638 |
Echinococcus granulosus | thioredoxin glutathione reductase | 0.0161 | 0.1089 | 0.1089 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0162 | 0.1093 | 0.3261 |
Mycobacterium tuberculosis | NAD(P)H quinone reductase LpdA | 0.0404 | 0.2875 | 0.8646 |
Onchocerca volvulus | 0.0026 | 0.01 | 0.0165 | |
Echinococcus granulosus | dihydrolipoamide dehydrogenase | 0.0055 | 0.0313 | 0.0313 |
Brugia malayi | hypoxia-induced factor 1 | 0.0306 | 0.2151 | 0.3095 |
Entamoeba histolytica | hypothetical protein | 0.0107 | 0.0692 | 1 |
Onchocerca volvulus | 0.0091 | 0.0573 | 0.1086 | |
Mycobacterium tuberculosis | Probable membrane NADH dehydrogenase NdhA | 0.0364 | 0.2577 | 0.7745 |
Trichomonas vaginalis | carboxylesterase domain containing protein, putative | 0.0162 | 0.1093 | 0.2097 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0118 | 0.0776 | 0.112 |
Mycobacterium ulcerans | beta-lactamase | 0.0073 | 0.0442 | 0.2133 |
Echinococcus multilocularis | microtubule associated protein 2 | 0.1375 | 1 | 1 |
Leishmania major | aldehyde dehydrogenase, mitochondrial precursor | 0.0182 | 0.1241 | 1 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0073 | 0.0442 | 0.0442 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0182 | 0.1241 | 0.6122 |
Brugia malayi | glutamate synthase | 0.0015 | 0.0015 | 0.0006 |
Plasmodium vivax | glutathione reductase, putative | 0.0159 | 0.1078 | 1 |
Leishmania major | 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein | 0.0055 | 0.0313 | 0.2431 |
Schistosoma mansoni | lamin | 0.0026 | 0.01 | 0.0085 |
Schistosoma mansoni | tar DNA-binding protein | 0.0065 | 0.0384 | 0.037 |
Schistosoma mansoni | acetylcholinesterase | 0.0162 | 0.1093 | 0.108 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0073 | 0.0442 | 0.083 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0091 | 0.0573 | 0.0559 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0073 | 0.0442 | 0.0638 |
Brugia malayi | hypothetical protein | 0.0162 | 0.1093 | 0.1566 |
Loa Loa (eye worm) | hypothetical protein | 0.0015 | 0.0015 | 0.0021 |
Brugia malayi | NADPH:adrenodoxin oxidoreductase, mitochondrial precursor | 0.0015 | 0.0015 | 0.0006 |
Brugia malayi | Carboxylesterase family protein | 0.0162 | 0.1093 | 0.1566 |
Loa Loa (eye worm) | hypothetical protein | 0.0162 | 0.1093 | 0.1578 |
Loa Loa (eye worm) | cytoplasmic intermediate filament protein | 0.0014 | 0.001 | 0.0015 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0274 | 0.1916 | 0.2755 |
Loa Loa (eye worm) | TAR-binding protein | 0.0065 | 0.0384 | 0.0555 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0073 | 0.0442 | 0.083 |
Loa Loa (eye worm) | hypothetical protein | 0.0073 | 0.0442 | 0.0638 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase | 0.0055 | 0.0313 | 0.2803 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0019 | 0.005 | 0.0072 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0073 | 0.0442 | 0.4018 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0096 | 0.0139 |
Leishmania major | PAS-domain containing phosphoglycerate kinase, putative | 0.0026 | 0.0095 | 0.0659 |
Onchocerca volvulus | 0.003 | 0.0129 | 0.0222 | |
Brugia malayi | hypothetical protein | 0.0331 | 0.234 | 0.3367 |
Echinococcus multilocularis | BC026374 protein (S09 family) | 0.0162 | 0.1093 | 0.1093 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0049 | 0.0267 | 0.0385 |
Plasmodium falciparum | dihydrolipoyl dehydrogenase, mitochondrial | 0.0055 | 0.0313 | 0.2803 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0107 | 0.0692 | 0.0692 |
Echinococcus granulosus | intermediate filament protein | 0.0026 | 0.01 | 0.01 |
Echinococcus multilocularis | neuropeptide s receptor | 0.0456 | 0.3254 | 0.3254 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0067 | 0.0402 | 0.0387 |
Schistosoma mansoni | intermediate filament proteins | 0.0026 | 0.01 | 0.0085 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0107 | 0.0692 | 0.0679 |
Mycobacterium tuberculosis | Probable lipase LipE | 0.0073 | 0.0442 | 0.1291 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0162 | 0.1093 | 0.3261 |
Loa Loa (eye worm) | thioredoxin reductase | 0.0159 | 0.1078 | 0.1555 |
Entamoeba histolytica | hypothetical protein | 0.0107 | 0.0692 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0274 | 0.1916 | 0.1904 |
Echinococcus multilocularis | apoptosis inducing factor 1 mitochondrial | 0.0015 | 0.0015 | 0.0015 |
Echinococcus multilocularis | sulfide:quinone oxidoreductase | 0.0015 | 0.0015 | 0.0015 |
Echinococcus multilocularis | acetylcholinesterase | 0.0957 | 0.6929 | 0.6929 |
Mycobacterium tuberculosis | Probable hydrolase | 0.0073 | 0.0442 | 0.1291 |
Loa Loa (eye worm) | CYP4Cod1 | 0.0019 | 0.005 | 0.0072 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0051 | 0.0285 | 0.2539 |
Trichomonas vaginalis | mercuric reductase, putative | 0.0055 | 0.0313 | 0.0579 |
Toxoplasma gondii | ABC1 family protein | 0.0073 | 0.0442 | 0.3483 |
Brugia malayi | TAR-binding protein | 0.0065 | 0.0384 | 0.0541 |
Onchocerca volvulus | 0.0073 | 0.0442 | 0.083 | |
Echinococcus granulosus | para nitrobenzyl esterase | 0.0162 | 0.1093 | 0.1093 |
Echinococcus granulosus | neuropeptide s receptor | 0.0456 | 0.3254 | 0.3254 |
Schistosoma mansoni | ferritin | 0.0017 | 0.0032 | 0.0017 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0274 | 0.1916 | 0.1916 |
Loa Loa (eye worm) | glutaminase | 0.0288 | 0.2017 | 0.2911 |
Schistosoma mansoni | lamin | 0.0026 | 0.01 | 0.0085 |
Trypanosoma cruzi | PAS-domain containing phosphoglycerate kinase, putative | 0.0026 | 0.0095 | 0.076 |
Echinococcus granulosus | expressed protein | 0.0017 | 0.0032 | 0.0032 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.0091 | 0.0573 | 0.0573 |
Echinococcus multilocularis | musashi | 0.0026 | 0.01 | 0.01 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0629 | 0.4521 | 0.6526 |
Brugia malayi | beta-lactamase family protein | 0.0073 | 0.0442 | 0.0624 |
Schistosoma mansoni | ferritin | 0.0017 | 0.0032 | 0.0017 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0026 | 0.01 | 0.0144 |
Schistosoma mansoni | tar DNA-binding protein | 0.0065 | 0.0384 | 0.037 |
Loa Loa (eye worm) | RNA binding protein | 0.0065 | 0.0384 | 0.0555 |
Toxoplasma gondii | histone lysine methyltransferase SET/SUV39 | 0.0091 | 0.0573 | 0.4555 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0404 | 0.2875 | 0.8646 |
Loa Loa (eye worm) | beta-lactamase | 0.0073 | 0.0442 | 0.0638 |
Mycobacterium ulcerans | bacterioferritin BfrA | 0.0017 | 0.0032 | 0.0086 |
Trypanosoma cruzi | dihydrolipoyl dehydrogenase, putative | 0.0055 | 0.0313 | 0.2803 |
Brugia malayi | glutaminase DH11.1 | 0.0288 | 0.2017 | 0.2901 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0065 | 0.0384 | 0.0541 |
Brugia malayi | Cytochrome P450 family protein | 0.0019 | 0.005 | 0.0057 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0957 | 0.6929 | 0.6924 |
Echinococcus granulosus | acetylcholinesterase | 0.0957 | 0.6929 | 0.6929 |
Wolbachia endosymbiont of Brugia malayi | bacterioferritin/cytochrome b1 | 0.0017 | 0.0032 | 0.0576 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0162 | 0.1093 | 0.108 |
Brugia malayi | glutathione reductase | 0.0159 | 0.1078 | 0.1543 |
Mycobacterium tuberculosis | Conserved protein | 0.0073 | 0.0442 | 0.1291 |
Mycobacterium tuberculosis | Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot | 0.0055 | 0.0313 | 0.0901 |
Onchocerca volvulus | 0.0162 | 0.1093 | 0.2097 | |
Trypanosoma brucei | dihydrolipoamide dehydrogenase | 0.0055 | 0.0313 | 0.2803 |
Schistosoma mansoni | hypothetical protein | 0.0023 | 0.0076 | 0.0062 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0055 | 0.0313 | 0.2803 |
Mycobacterium leprae | conserved hypothetical protein | 0.0073 | 0.0442 | 0.1493 |
Leishmania major | protein kinase, putative | 0.0026 | 0.0095 | 0.0659 |
Toxoplasma gondii | aldehyde dehydrogenase | 0.0182 | 0.1241 | 1 |
Schistosoma mansoni | cpg binding protein | 0.0032 | 0.0141 | 0.0127 |
Echinococcus multilocularis | dihydrolipoamide dehydrogenase | 0.0055 | 0.0313 | 0.0313 |
Echinococcus granulosus | BC026374 protein S09 family | 0.0162 | 0.1093 | 0.1093 |
Mycobacterium tuberculosis | Probable bacterioferritin BfrA | 0.0017 | 0.0032 | 0.0052 |
Trypanosoma brucei | dihydrolipoyl dehydrogenase | 0.0055 | 0.0313 | 0.2803 |
Trichomonas vaginalis | esterase, putative | 0.0073 | 0.0442 | 0.083 |
Loa Loa (eye worm) | hypothetical protein | 0.0084 | 0.0523 | 0.0755 |
Mycobacterium ulcerans | cytochrome P450 185A4 Cyp185A4 | 0.0019 | 0.005 | 0.0176 |
Trichomonas vaginalis | adenylate and guanylate cyclases, putative | 0.0026 | 0.0095 | 0.0157 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0159 | 0.1078 | 1 |
Plasmodium vivax | dihydrolipoyl dehydrogenase, apicoplast, putative | 0.0055 | 0.0313 | 0.2803 |
Plasmodium falciparum | thioredoxin reductase | 0.0159 | 0.1078 | 1 |
Schistosoma mansoni | apoferritin-2 | 0.0017 | 0.0032 | 0.0017 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0073 | 0.0442 | 0.4018 |
Loa Loa (eye worm) | pyridine nucleotide-disufhide oxidoreductase | 0.0015 | 0.0015 | 0.0021 |
Trypanosoma cruzi | dihydrolipoyl dehydrogenase, putative | 0.0055 | 0.0313 | 0.2803 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.0091 | 0.0573 | 0.0573 |
Trichomonas vaginalis | glutathione reductase, putative | 0.0055 | 0.0313 | 0.0579 |
Schistosoma mansoni | aryl hydrocarbon receptor | 0.0099 | 0.0632 | 0.0618 |
Echinococcus multilocularis | thioredoxin glutathione reductase | 0.0161 | 0.1089 | 0.1089 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0182 | 0.1241 | 0.6122 |
Trichomonas vaginalis | adenylate and guanylate cyclases, putative | 0.0026 | 0.0095 | 0.0157 |
Plasmodium falciparum | glutathione reductase | 0.0055 | 0.0313 | 0.2803 |
Brugia malayi | Pre-SET motif family protein | 0.0629 | 0.4521 | 0.652 |
Mycobacterium leprae | PROBABLE BACTERIOFERRITIN BFRA | 0.0017 | 0.0032 | 0.006 |
Plasmodium vivax | hypothetical protein, conserved | 0.0073 | 0.0442 | 0.4018 |
Mycobacterium tuberculosis | Bacterioferritin BfrB | 0.0017 | 0.0032 | 0.0052 |
Brugia malayi | beta-lactamase family protein | 0.0073 | 0.0442 | 0.0624 |
Brugia malayi | intermediate filament protein | 0.0026 | 0.01 | 0.0129 |
Mycobacterium ulcerans | lipase LipD | 0.0073 | 0.0442 | 0.2133 |
Mycobacterium ulcerans | putative regulatory protein | 0.0073 | 0.0444 | 0.2142 |
Trichomonas vaginalis | adenylate and guanylate cyclases, putative | 0.0026 | 0.0095 | 0.0157 |
Echinococcus multilocularis | Bcl 2 ous antagonist:killer | 0.0084 | 0.0523 | 0.0523 |
Echinococcus granulosus | Aryl hydrocarbon receptor nuclear | 0.0026 | 0.0095 | 0.0095 |
Onchocerca volvulus | 0.0073 | 0.0442 | 0.083 | |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0026 | 0.01 | 0.0129 |
Echinococcus granulosus | EGFP:Bcl2 fusion protein | 0.0084 | 0.0523 | 0.0523 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0274 | 0.1916 | 0.2766 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.0285 | 0.0411 |
Mycobacterium tuberculosis | Probable reductase | 0.0364 | 0.2577 | 0.7745 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0051 | 0.0285 | 0.2539 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0274 | 0.1916 | 0.1904 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase, point mutation | 0.0055 | 0.0313 | 0.2803 |
Schistosoma mansoni | apoferritin-2 | 0.0017 | 0.0032 | 0.0017 |
Plasmodium falciparum | dihydrolipoyl dehydrogenase, apicoplast | 0.0055 | 0.0313 | 0.2803 |
Echinococcus granulosus | apoptosis inducing factor 1 mitochondrial | 0.0015 | 0.0015 | 0.0015 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0274 | 0.1916 | 0.1916 |
Mycobacterium tuberculosis | Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras | 0.0404 | 0.2875 | 0.8646 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0091 | 0.0573 | 0.0559 |
Loa Loa (eye worm) | programmed cell death 8 | 0.0015 | 0.0015 | 0.0021 |
Leishmania major | trypanothione reductase | 0.0159 | 0.1078 | 0.8671 |
Trypanosoma brucei | trypanothione reductase | 0.0159 | 0.1078 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0065 | 0.0384 | 0.037 |
Wolbachia endosymbiont of Brugia malayi | dihydrolipoamide dehydrogenase E3 component | 0.0055 | 0.0313 | 1 |
Plasmodium vivax | SET domain protein, putative | 0.0091 | 0.0573 | 0.5253 |
Echinococcus multilocularis | neuropeptide receptor A26 | 0.0456 | 0.3254 | 0.3254 |
Schistosoma mansoni | hypothetical protein | 0.0084 | 0.0523 | 0.0509 |
Echinococcus granulosus | tar DNA binding protein | 0.0065 | 0.0384 | 0.0384 |
Brugia malayi | Cytochrome P450 family protein | 0.0019 | 0.005 | 0.0057 |
Loa Loa (eye worm) | hypothetical protein | 0.0073 | 0.0442 | 0.0638 |
Echinococcus granulosus | aldehyde dehydrogenase mitochondrial | 0.0182 | 0.1241 | 0.1241 |
Mycobacterium tuberculosis | Probable lipase LipD | 0.0073 | 0.0442 | 0.1291 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0274 | 0.1916 | 0.1904 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0073 | 0.0442 | 0.083 |
Echinococcus multilocularis | geminin | 0.0662 | 0.4767 | 0.4767 |
Echinococcus granulosus | neuroligin | 0.0162 | 0.1093 | 0.1093 |
Echinococcus granulosus | single minded 2 | 0.0073 | 0.0444 | 0.0444 |
Mycobacterium ulcerans | fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE | 0.0073 | 0.0442 | 0.2133 |
Loa Loa (eye worm) | glutaminase 2 | 0.0288 | 0.2017 | 0.2911 |
Echinococcus multilocularis | expressed protein | 0.0017 | 0.0032 | 0.0032 |
Brugia malayi | dihydrolipoyl dehydrogenase, mitochondrial precursor, putative | 0.0055 | 0.0313 | 0.0437 |
Echinococcus multilocularis | tar DNA binding protein | 0.0065 | 0.0384 | 0.0384 |
Schistosoma mansoni | hypothetical protein | 0.0084 | 0.0523 | 0.0509 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0065 | 0.0384 | 0.0555 |
Entamoeba histolytica | hypothetical protein | 0.0107 | 0.0692 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0162 | 0.1093 | 0.1578 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0091 | 0.0573 | 0.0573 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.