Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | thioredoxin glutathione reductase | 0.0047 | 0.0327 | 0.0363 |
Loa Loa (eye worm) | UDP-N-acetylglucosamine-peptide N-acetylglucosaminyltransferase | 0.0041 | 0.0279 | 0.0304 |
Loa Loa (eye worm) | hypothetical protein | 0.0066 | 0.047 | 0.0541 |
Trypanosoma cruzi | cytochrome P450, putative | 0.0012 | 0.0059 | 0.0007 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0066 | 0.047 | 0.0578 |
Trypanosoma cruzi | Adenine phosphoribosyltransferase, putative | 0.0015 | 0.0077 | 0.0025 |
Schistosoma mansoni | neuropeptide receptor | 0.0066 | 0.047 | 0.0578 |
Loa Loa (eye worm) | hypothetical protein | 0.0066 | 0.047 | 0.0541 |
Echinococcus granulosus | neuropeptide FF receptor 2 | 0.0066 | 0.047 | 0.054 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0066 | 0.047 | 0.054 |
Loa Loa (eye worm) | unidentified vitellogenin-linked transcript protein 6 | 0.0066 | 0.047 | 0.0541 |
Echinococcus multilocularis | lamin | 0.0027 | 0.0171 | 0.017 |
Schistosoma mansoni | DNA helicase recq5 | 0.0009 | 0.0033 | 0.004 |
Echinococcus multilocularis | thioredoxin glutathione reductase | 0.0047 | 0.0327 | 0.0363 |
Brugia malayi | larval opioid receptor | 0.0066 | 0.047 | 0.054 |
Loa Loa (eye worm) | hypothetical protein | 0.0066 | 0.047 | 0.0541 |
Mycobacterium ulcerans | 6-phosphofructokinase | 0.0109 | 0.0796 | 0.0913 |
Loa Loa (eye worm) | hypothetical protein | 0.0066 | 0.047 | 0.0541 |
Echinococcus granulosus | sex peptide receptor | 0.0066 | 0.047 | 0.054 |
Loa Loa (eye worm) | hypothetical protein | 0.0066 | 0.047 | 0.0541 |
Trichomonas vaginalis | ribose-phosphate pyrophosphokinase, putative | 0.0015 | 0.0077 | 0.0065 |
Loa Loa (eye worm) | hypothetical protein | 0.0066 | 0.047 | 0.0541 |
Entamoeba histolytica | phosphofructokinase, putative | 0.0109 | 0.0796 | 1 |
Plasmodium falciparum | orotate phosphoribosyltransferase | 0.0049 | 0.0338 | 0.0306 |
Brugia malayi | Thioredoxin reductase | 0.0047 | 0.0327 | 0.0363 |
Toxoplasma gondii | bifunctional dihydrofolate reductase-thymidylate synthase | 0.1313 | 1 | 1 |
Echinococcus granulosus | thymidylate synthase | 0.1068 | 0.8124 | 1 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0066 | 0.047 | 0.054 |
Onchocerca volvulus | 0.0066 | 0.047 | 0.0488 | |
Schistosoma mansoni | peptide (FMRFamide/somatostatin)-like receptor | 0.0066 | 0.047 | 0.0578 |
Onchocerca volvulus | 0.0066 | 0.047 | 0.0488 | |
Plasmodium falciparum | orotidine 5'-phosphate decarboxylase | 0.014 | 0.1034 | 0.1004 |
Trypanosoma cruzi | hypoxanthine-guanine phosphoribosyltransferase, putative | 0.0015 | 0.0077 | 0.0025 |
Brugia malayi | GnHR receptor homolog | 0.0066 | 0.047 | 0.054 |
Trypanosoma cruzi | hypoxanthine-guanine phosphoribosyltransferase, putative | 0.0015 | 0.0077 | 0.0025 |
Echinococcus multilocularis | hypoxanthine guanine phosphoribosyltransferase | 0.0015 | 0.0077 | 0.0055 |
Echinococcus multilocularis | somatostatin receptor | 0.0066 | 0.047 | 0.054 |
Toxoplasma gondii | ATP-dependent DNA helicase, RecQ family protein | 0.0014 | 0.0074 | 0.0074 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0066 | 0.047 | 0.054 |
Schistosoma mansoni | hypoxanthine-guanine phosphoribosyltransferase | 0.0015 | 0.0077 | 0.0095 |
Mycobacterium leprae | DIHYDROFOLATE REDUCTASE DFRA (DHFR) (TETRAHYDROFOLATE DEHYDROGENASE) | 0.0462 | 0.3495 | 0.4248 |
Echinococcus multilocularis | bloom syndrome protein | 0.0021 | 0.0128 | 0.0117 |
Echinococcus multilocularis | neuropeptide s receptor | 0.0066 | 0.047 | 0.054 |
Plasmodium vivax | glutathione reductase, putative | 0.0047 | 0.0327 | 0.0253 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase | 0.0016 | 0.0091 | 0.0039 |
Onchocerca volvulus | 0.0066 | 0.047 | 0.0488 | |
Trypanosoma cruzi | ATP-dependent 6-phosphofructokinase, glycosomal | 0.0109 | 0.0796 | 0.0747 |
Entamoeba histolytica | phosphofructokinase, putative | 0.0109 | 0.0796 | 1 |
Trypanosoma cruzi | deoxyuridine triphosphatase, putative | 0.0355 | 0.2676 | 0.2638 |
Echinococcus multilocularis | 6 phosphofructokinase | 0.0109 | 0.0796 | 0.0943 |
Echinococcus granulosus | biogenic amine 5HT receptor | 0.0066 | 0.047 | 0.054 |
Chlamydia trachomatis | fructose-6-phosphate phosphotransferase | 0.0029 | 0.019 | 0.0298 |
Echinococcus granulosus | tachykinin peptides receptor 99D | 0.0066 | 0.047 | 0.054 |
Toxoplasma gondii | ATP-dependent DNA helicase, RecQ family protein | 0.0009 | 0.0033 | 0.0033 |
Loa Loa (eye worm) | hypothetical protein | 0.0066 | 0.047 | 0.0541 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0066 | 0.047 | 0.054 |
Trypanosoma cruzi | dihydrolipoyl dehydrogenase, putative | 0.0016 | 0.0091 | 0.0039 |
Trypanosoma brucei | hypoxanthine-guanine phosphoribosyltransferase | 0.0015 | 0.0077 | 0.0025 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0066 | 0.047 | 0.0578 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0066 | 0.047 | 0.0578 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0029 | 0.019 | 0.0363 |
Brugia malayi | gonadotropin-releasing hormone receptor 2 | 0.0066 | 0.047 | 0.054 |
Brugia malayi | G protein-coupled receptor F59B2.13 | 0.0066 | 0.047 | 0.054 |
Toxoplasma gondii | NADPH-glutathione reductase | 0.0016 | 0.0091 | 0.0091 |
Plasmodium vivax | dihydrolipoyl dehydrogenase, apicoplast, putative | 0.0016 | 0.0091 | 0.0016 |
Loa Loa (eye worm) | hypothetical protein | 0.0013 | 0.0065 | 0.004 |
Echinococcus multilocularis | fmrfamide receptor | 0.0066 | 0.047 | 0.054 |
Loa Loa (eye worm) | RecQ helicase | 0.0021 | 0.0128 | 0.0118 |
Trypanosoma brucei | Adenine phosphoribosyltransferase, putative | 0.0015 | 0.0077 | 0.0025 |
Brugia malayi | cytoplasmic intermediate filament protein | 0.0014 | 0.0076 | 0.0053 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0027 | 0.0171 | 0.0171 |
Schistosoma mansoni | hypoxanthine-guanine phosphoribosyltransferase | 0.0015 | 0.0077 | 0.0095 |
Schistosoma mansoni | Adenine phosphoribosyltransferase | 0.0015 | 0.0077 | 0.0095 |
Trichomonas vaginalis | hypoxanthine-guanine phosphoribosyltransferase, putative | 0.0015 | 0.0077 | 0.0065 |
Loa Loa (eye worm) | neuropeptide F receptor | 0.0066 | 0.047 | 0.0541 |
Trypanosoma cruzi | orotidine-5-phosphate decarboxylase/orotate phosphoribosyltransferase, putative | 0.014 | 0.1034 | 0.0987 |
Trypanosoma cruzi | hypoxanthine-guanine phosphoribosyltransferase, putative | 0.0015 | 0.0077 | 0.0025 |
Loa Loa (eye worm) | follicle stimulating hormone receptor | 0.0294 | 0.2215 | 0.2697 |
Treponema pallidum | hypothetical protein | 0.0016 | 0.0089 | 0.1115 |
Schistosoma mansoni | 6-phosphofructokinase | 0.0109 | 0.0796 | 0.0979 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0029 | 0.019 | 0.0363 |
Schistosoma mansoni | neuropeptide F-like receptor | 0.0066 | 0.047 | 0.0578 |
Schistosoma mansoni | neuropeptide F-like receptor | 0.0066 | 0.047 | 0.0578 |
Onchocerca volvulus | 0.0066 | 0.047 | 0.0488 | |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0066 | 0.047 | 0.054 |
Loa Loa (eye worm) | hypothetical protein | 0.0066 | 0.047 | 0.0541 |
Loa Loa (eye worm) | G-protein coupled receptor | 0.0066 | 0.047 | 0.0541 |
Brugia malayi | hypothetical protein | 0.0066 | 0.047 | 0.054 |
Trypanosoma cruzi | hypoxanthine-guanine phosphoribosyltransferase, putative | 0.0015 | 0.0077 | 0.0025 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0016 | 0.0091 | 0.0039 |
Loa Loa (eye worm) | hypothetical protein | 0.0066 | 0.047 | 0.0541 |
Onchocerca volvulus | 0.0027 | 0.0171 | 0.0116 | |
Schistosoma mansoni | hypoxanthine-guanine phosphoribosyltransferase | 0.0015 | 0.0077 | 0.0095 |
Toxoplasma gondii | ATP-dependent DNA helicase, RecQ family protein | 0.0009 | 0.0033 | 0.0033 |
Loa Loa (eye worm) | hypothetical protein | 0.0066 | 0.047 | 0.0541 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0066 | 0.047 | 0.054 |
Brugia malayi | hypothetical protein | 0.0066 | 0.047 | 0.054 |
Giardia lamblia | Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit | 0.0029 | 0.019 | 0.6459 |
Schistosoma mansoni | hypothetical protein | 0.0066 | 0.047 | 0.0578 |
Giardia lamblia | Adenine phosphoribosyltransferase | 0.0015 | 0.0077 | 0.1827 |
Leishmania major | deoxyuridine triphosphatase, putative,dUTP diphosphatase | 0.0355 | 0.2676 | 0.2638 |
Echinococcus multilocularis | g protein coupled receptor | 0.0066 | 0.047 | 0.054 |
Brugia malayi | hypothetical protein | 0.0066 | 0.047 | 0.054 |
Brugia malayi | Adenine phosphoribosyltransferase | 0.0015 | 0.0077 | 0.0055 |
Mycobacterium leprae | Probable orotidine 5'-phosphate decarboxylase PyrF (OMP decarboxylase) (OMPDCase) (OMPdecase) | 0.014 | 0.1034 | 0.1189 |
Echinococcus granulosus | allatostatin A receptor | 0.0066 | 0.047 | 0.054 |
Echinococcus multilocularis | neuropeptide receptor | 0.0066 | 0.047 | 0.054 |
Trichomonas vaginalis | Ribose-phosphate pyrophosphokinase, putative | 0.0015 | 0.0077 | 0.0065 |
Plasmodium vivax | 6-phosphofructokinase, putative | 0.0029 | 0.019 | 0.0116 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0109 | 0.0796 | 0.1959 |
Loa Loa (eye worm) | hypothetical protein | 0.0066 | 0.047 | 0.0541 |
Echinococcus granulosus | adenine phosphoribosyltransferase | 0.0015 | 0.0077 | 0.0055 |
Leishmania major | trypanothione reductase | 0.0047 | 0.0327 | 0.0276 |
Echinococcus granulosus | g protein coupled receptor | 0.0066 | 0.047 | 0.054 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0016 | 0.0091 | 0.0039 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0029 | 0.019 | 0.0363 |
Mycobacterium ulcerans | orotidine 5'-phosphate decarboxylase | 0.014 | 0.1034 | 0.1208 |
Schistosoma mansoni | peptide (allatostatin/somatostatin)-like receptor | 0.0066 | 0.047 | 0.0578 |
Echinococcus granulosus | neuropeptide s receptor | 0.0066 | 0.047 | 0.054 |
Leishmania major | dihydrolipoamide dehydrogenase, putative | 0.0016 | 0.0091 | 0.0039 |
Echinococcus granulosus | bloom syndrome protein | 0.0021 | 0.0128 | 0.0117 |
Brugia malayi | Serotonin/octopamine receptor family protein 7 | 0.0066 | 0.047 | 0.054 |
Schistosoma mansoni | opsin-like receptor | 0.0066 | 0.047 | 0.0578 |
Loa Loa (eye worm) | dihydrofolate reductase | 0.0462 | 0.3495 | 0.428 |
Echinococcus granulosus | g protein coupled receptor | 0.0066 | 0.047 | 0.054 |
Echinococcus granulosus | g-protein coupled receptor | 0.0066 | 0.047 | 0.054 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0066 | 0.047 | 0.0578 |
Toxoplasma gondii | 6-phosphofructokinase | 0.0029 | 0.019 | 0.019 |
Loa Loa (eye worm) | hypothetical protein | 0.0066 | 0.047 | 0.0541 |
Onchocerca volvulus | 0.0027 | 0.0171 | 0.0116 | |
Echinococcus multilocularis | neuropeptide Y receptor | 0.0066 | 0.047 | 0.054 |
Toxoplasma gondii | hypoxanthine-xanthine-guanine phosphoribosyl transferase HXGPRT | 0.0015 | 0.0077 | 0.0077 |
Echinococcus multilocularis | dro:myosuppressin receptor | 0.0066 | 0.047 | 0.054 |
Schistosoma mansoni | neuropeptide f receptor 76f | 0.0066 | 0.047 | 0.0578 |
Schistosoma mansoni | histamine-responsive GPCR (AAF21638) | 0.0066 | 0.047 | 0.0578 |
Echinococcus granulosus | neuropeptides capa receptor | 0.0066 | 0.047 | 0.054 |
Brugia malayi | glutathione reductase | 0.0047 | 0.0327 | 0.0363 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0066 | 0.047 | 0.054 |
Trypanosoma brucei | hypoxanthine-guanine phosphoribosyltransferase, putative | 0.0015 | 0.0077 | 0.0025 |
Loa Loa (eye worm) | hypothetical protein | 0.0066 | 0.047 | 0.0541 |
Giardia lamblia | O-linked GlcNAc transferase | 0.0024 | 0.0148 | 0.4715 |
Treponema pallidum | NADH oxidase | 0.0016 | 0.0091 | 0.1144 |
Plasmodium vivax | 6-phosphofructokinase, putative | 0.0029 | 0.019 | 0.0116 |
Echinococcus multilocularis | sex peptide receptor | 0.0066 | 0.047 | 0.054 |
Schistosoma mansoni | biogenic amine receptor | 0.0066 | 0.047 | 0.0578 |
Loa Loa (eye worm) | hypothetical protein | 0.0066 | 0.047 | 0.0541 |
Brugia malayi | phosphofructokinase | 0.0109 | 0.0796 | 0.0943 |
Echinococcus granulosus | intermediate filament protein | 0.0027 | 0.0171 | 0.017 |
Treponema pallidum | diphosphate--fructose-6-phosphate 1-phosphotransferase | 0.0029 | 0.019 | 0.2389 |
Trypanosoma brucei | trypanothione reductase | 0.0047 | 0.0327 | 0.0276 |
Echinococcus multilocularis | g protein linked acetylcholine receptor gar 2a | 0.0066 | 0.047 | 0.054 |
Schistosoma mansoni | o-linked n-acetylglucosamine transferase ogt | 0.0041 | 0.028 | 0.0344 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0167 | 0.0166 |
Brugia malayi | sulfakinin receptor protein | 0.0066 | 0.047 | 0.054 |
Schistosoma mansoni | lamin | 0.0027 | 0.0171 | 0.021 |
Brugia malayi | Dopamine receptor protein 2 | 0.0066 | 0.047 | 0.054 |
Toxoplasma gondii | phosphofructokinase PFKII | 0.0029 | 0.019 | 0.019 |
Brugia malayi | Dopamine receptor | 0.0066 | 0.047 | 0.054 |
Schistosoma mansoni | Adenine phosphoribosyltransferase | 0.0015 | 0.0077 | 0.0095 |
Trypanosoma cruzi | cytochrome P450, putative | 0.0012 | 0.0059 | 0.0007 |
Schistosoma mansoni | biogenic amine (5HT) receptor | 0.0066 | 0.047 | 0.0578 |
Echinococcus multilocularis | lamin dm0 | 0.0027 | 0.0171 | 0.017 |
Echinococcus granulosus | hypothetical protein | 0.0066 | 0.047 | 0.054 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0027 | 0.0171 | 0.017 |
Plasmodium falciparum | ADP-dependent DNA helicase RecQ | 0.0019 | 0.0108 | 0.0076 |
Schistosoma mansoni | DNA helicase recq1 | 0.0009 | 0.0033 | 0.004 |
Loa Loa (eye worm) | hypothetical protein | 0.0066 | 0.047 | 0.0541 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0109 | 0.0796 | 0.1959 |
Giardia lamblia | O-linked GlcNAc transferase | 0.0041 | 0.0276 | 1 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0066 | 0.047 | 0.0578 |
Echinococcus multilocularis | biogenic amine (5HT) receptor | 0.0066 | 0.047 | 0.054 |
Loa Loa (eye worm) | hypothetical protein | 0.0066 | 0.047 | 0.0541 |
Loa Loa (eye worm) | hypothetical protein | 0.0066 | 0.047 | 0.0541 |
Onchocerca volvulus | 0.1068 | 0.8124 | 1 | |
Trichomonas vaginalis | glutathione reductase, putative | 0.0016 | 0.0091 | 0.0102 |
Echinococcus granulosus | 6 phosphofructokinase | 0.0109 | 0.0796 | 0.0943 |
Loa Loa (eye worm) | orotate phosphoribosyltransferase | 0.0154 | 0.1145 | 0.1375 |
Echinococcus multilocularis | adenine phosphoribosyltransferase | 0.0015 | 0.0077 | 0.0055 |
Echinococcus multilocularis | thyrotropin releasing hormone receptor | 0.0066 | 0.047 | 0.054 |
Onchocerca volvulus | 0.0066 | 0.047 | 0.0488 | |
Schistosoma mansoni | adenoreceptor | 0.0066 | 0.047 | 0.0578 |
Toxoplasma gondii | orotidine-5-phosphate decarboxylase/orotate phosphoribosyltransferase | 0.014 | 0.1034 | 0.1034 |
Loa Loa (eye worm) | hypothetical protein | 0.0066 | 0.047 | 0.0541 |
Mycobacterium leprae | PROBABLE NADH DEHYDROGENASE NDH | 0.0108 | 0.0789 | 0.0885 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0109 | 0.0796 | 0.1959 |
Treponema pallidum | phosphoribosylpyrophosphate synthetase | 0.0015 | 0.0077 | 0.0971 |
Brugia malayi | Dihydrofolate reductase | 0.0462 | 0.3495 | 0.4279 |
Brugia malayi | Cytochrome P450 family protein | 0.0012 | 0.0059 | 0.0033 |
Mycobacterium leprae | PROBABLE THYMIDYLATE SYNTHASE THYA (TS) (TSASE) | 0.1068 | 0.8124 | 1 |
Giardia lamblia | NADH oxidase lateral transfer candidate | 0.0016 | 0.0091 | 0.2391 |
Schistosoma mansoni | amine GPCR | 0.0066 | 0.047 | 0.0578 |
Echinococcus multilocularis | thymidylate synthase | 0.1068 | 0.8124 | 1 |
Mycobacterium ulcerans | adenine phosphoribosyltransferase | 0.0015 | 0.0077 | 0.0022 |
Echinococcus granulosus | neuropeptide receptor | 0.0066 | 0.047 | 0.054 |
Brugia malayi | 6-phosphofructokinase | 0.0109 | 0.0796 | 0.0943 |
Leishmania major | dihydrolipoamide dehydrogenase, putative | 0.0016 | 0.0091 | 0.0039 |
Onchocerca volvulus | 0.0566 | 0.4289 | 0.5234 | |
Plasmodium vivax | dihydrolipoyl dehydrogenase, mitochondrial, putative | 0.0016 | 0.0091 | 0.0016 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0066 | 0.047 | 0.054 |
Mycobacterium tuberculosis | Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras | 0.012 | 0.0881 | 0.0999 |
Trypanosoma brucei | dihydrolipoyl dehydrogenase | 0.0016 | 0.0091 | 0.0039 |
Leishmania major | orotidine-5-phosphate decarboxylase/orotate phosphoribosyltransferase, putative,OMPDCase-OPRTase, putative | 0.0154 | 0.1145 | 0.1098 |
Plasmodium vivax | bifunctional dihydrofolate reductase-thymidylate synthase, putative | 0.1313 | 1 | 1 |
Trichomonas vaginalis | 6-phosphofructokinase, putative | 0.0029 | 0.019 | 0.0363 |
Brugia malayi | hypothetical protein | 0.0066 | 0.047 | 0.054 |
Echinococcus granulosus | fmrfamide receptor | 0.0066 | 0.047 | 0.054 |
Loa Loa (eye worm) | hypothetical protein | 0.0066 | 0.047 | 0.0541 |
Loa Loa (eye worm) | hypothetical protein | 0.0066 | 0.047 | 0.0541 |
Mycobacterium ulcerans | amidophosphoribosyltransferase | 0.0015 | 0.0077 | 0.0022 |
Echinococcus multilocularis | g protein linked acetylcholine receptor gar 2a | 0.0066 | 0.047 | 0.054 |
Wolbachia endosymbiont of Brugia malayi | dihydrolipoamide dehydrogenase E3 component | 0.0016 | 0.0091 | 0.0027 |
Echinococcus multilocularis | tachykinin peptides receptor 99D | 0.0066 | 0.047 | 0.054 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0508 | 0.3847 | 1 |
Schistosoma mansoni | amine GPCR | 0.0066 | 0.047 | 0.0578 |
Brugia malayi | Dopamine receptor protein 1 | 0.0066 | 0.047 | 0.054 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0066 | 0.047 | 0.0578 |
Plasmodium vivax | orotidine 5'-phosphate decarboxylase, putative | 0.014 | 0.1034 | 0.0966 |
Echinococcus multilocularis | cytoplasmic intermediate filament protein | 0.0013 | 0.0065 | 0.0039 |
Echinococcus multilocularis | allatostatin A receptor | 0.0066 | 0.047 | 0.054 |
Schistosoma mansoni | hypothetical protein | 0.0066 | 0.047 | 0.0578 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0066 | 0.047 | 0.0578 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0171 | 0.0171 |
Plasmodium falciparum | thioredoxin reductase | 0.0016 | 0.0091 | 0.0058 |
Mycobacterium ulcerans | orotate phosphoribosyltransferase | 0.0049 | 0.0338 | 0.0345 |
Mycobacterium leprae | PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) | 0.0109 | 0.0796 | 0.0893 |
Echinococcus granulosus | neuropeptide Y receptor | 0.0066 | 0.047 | 0.054 |
Mycobacterium tuberculosis | Probable thymidylate synthase ThyA (ts) (TSASE) | 0.1068 | 0.8124 | 1 |
Plasmodium falciparum | hypoxanthine-guanine phosphoribosyltransferase | 0.0015 | 0.0077 | 0.0045 |
Trypanosoma cruzi | orotidine-5-phosphate decarboxylase/orotate phosphoribosyltransferase, putative | 0.0154 | 0.1145 | 0.1098 |
Leishmania major | acetoin dehydrogenase e3 component-like protein | 0.0016 | 0.0091 | 0.0039 |
Echinococcus granulosus | biogenic amine 5HT receptor | 0.0066 | 0.047 | 0.054 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase | 0.0016 | 0.0091 | 0.0039 |
Loa Loa (eye worm) | G-protein coupled receptor | 0.0066 | 0.047 | 0.0541 |
Schistosoma mansoni | neuropeptide receptor | 0.0066 | 0.047 | 0.0578 |
Brugia malayi | Unidentified vitellogenin-linked transcript protein 6, putative | 0.0066 | 0.047 | 0.054 |
Brugia malayi | intermediate filament protein | 0.0027 | 0.0171 | 0.017 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0066 | 0.047 | 0.054 |
Echinococcus granulosus | alpha 1A adrenergic receptor | 0.0066 | 0.047 | 0.054 |
Wolbachia endosymbiont of Brugia malayi | hypothetical protein | 0.0016 | 0.0089 | 0.0023 |
Echinococcus granulosus | serotonin receptor | 0.0066 | 0.047 | 0.054 |
Trypanosoma cruzi | deoxyuridine triphosphatase, putative | 0.0355 | 0.2676 | 0.2638 |
Echinococcus multilocularis | neuropeptide FF receptor 2 | 0.0066 | 0.047 | 0.054 |
Trypanosoma cruzi | Adenine phosphoribosyltransferase, putative | 0.0015 | 0.0077 | 0.0025 |
Mycobacterium ulcerans | hypothetical protein | 0.0015 | 0.0077 | 0.0022 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0066 | 0.047 | 0.0578 |
Echinococcus multilocularis | neuropeptides capa receptor | 0.0066 | 0.047 | 0.054 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase, point mutation | 0.0016 | 0.0091 | 0.0039 |
Brugia malayi | neuropeptide F receptor | 0.0066 | 0.047 | 0.054 |
Loa Loa (eye worm) | glutathione reductase | 0.0047 | 0.0327 | 0.0364 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0047 | 0.0327 | 0.0276 |
Brugia malayi | G-protein coupled receptor | 0.0066 | 0.047 | 0.054 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0012 | 0.0059 | 0.0033 |
Schistosoma mansoni | biogenic amine receptor | 0.0066 | 0.047 | 0.0578 |
Echinococcus granulosus | hypoxanthine guanine phosphoribosyltransferase | 0.0015 | 0.0077 | 0.0055 |
Leishmania major | hypoxanthine-guanine phosphoribosyltransferase | 0.0015 | 0.0077 | 0.0025 |
Schistosoma mansoni | histamine h1 receptor | 0.0066 | 0.047 | 0.0578 |
Echinococcus granulosus | lamin dm0 | 0.0027 | 0.0171 | 0.017 |
Echinococcus granulosus | cytoplasmic intermediate filament protein | 0.0013 | 0.0065 | 0.0039 |
Plasmodium vivax | thioredoxin reductase, putative | 0.0047 | 0.0327 | 0.0253 |
Echinococcus granulosus | neuropeptides capa receptor | 0.0066 | 0.047 | 0.054 |
Leishmania major | 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein | 0.0016 | 0.0091 | 0.0039 |
Plasmodium falciparum | dihydrolipoyl dehydrogenase, apicoplast | 0.0016 | 0.0091 | 0.0058 |
Echinococcus granulosus | O glycosyltransferase | 0.0041 | 0.028 | 0.0305 |
Mycobacterium ulcerans | hypothetical protein | 0.0016 | 0.0089 | 0.0037 |
Echinococcus granulosus | 7TM GPCR rhodopsin | 0.0066 | 0.047 | 0.054 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0109 | 0.0796 | 0.1959 |
Mycobacterium tuberculosis | Probable membrane NADH dehydrogenase NdhA | 0.0108 | 0.0789 | 0.0885 |
Toxoplasma gondii | thioredoxin reductase | 0.0047 | 0.0327 | 0.0327 |
Brugia malayi | hypothetical protein | 0.0066 | 0.047 | 0.054 |
Mycobacterium ulcerans | dihydrolipoamide dehydrogenase | 0.0016 | 0.0091 | 0.0039 |
Trichomonas vaginalis | DNA helicase recq1, putative | 0.0021 | 0.0128 | 0.0199 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0016 | 0.0091 | 0.0039 |
Onchocerca volvulus | 0.0066 | 0.047 | 0.0488 | |
Loa Loa (eye worm) | hypothetical protein | 0.0066 | 0.047 | 0.0541 |
Loa Loa (eye worm) | TYRA-2 protein | 0.0066 | 0.047 | 0.0541 |
Echinococcus multilocularis | serotonin receptor | 0.0066 | 0.047 | 0.054 |
Brugia malayi | G-protein coupled receptor | 0.0066 | 0.047 | 0.054 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0066 | 0.047 | 0.0578 |
Brugia malayi | Dopamine receptor protein 1, putative (partial) | 0.0066 | 0.047 | 0.054 |
Echinococcus granulosus | dro:myosuppressin receptor | 0.0066 | 0.047 | 0.054 |
Chlamydia trachomatis | dihydrofolate reductase | 0.0462 | 0.3495 | 1 |
Brugia malayi | putative neuropeptide receptor | 0.0066 | 0.047 | 0.054 |
Schistosoma mansoni | myosin xvIII | 0.0066 | 0.047 | 0.0578 |
Loa Loa (eye worm) | phosphofructokinase | 0.0109 | 0.0796 | 0.0943 |
Schistosoma mansoni | opsin-like receptor | 0.0066 | 0.047 | 0.0578 |
Brugia malayi | neuropeptide F receptor | 0.0066 | 0.047 | 0.054 |
Brugia malayi | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase | 0.0041 | 0.0279 | 0.0304 |
Schistosoma mansoni | hypothetical protein | 0.0066 | 0.047 | 0.0578 |
Schistosoma mansoni | uracil phosphoribosyltransferase | 0.0015 | 0.0077 | 0.0095 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0066 | 0.047 | 0.054 |
Echinococcus multilocularis | pyroglutamylated rfamide peptide receptor | 0.0066 | 0.047 | 0.054 |
Mycobacterium tuberculosis | NADPH-dependent mycothiol reductase Mtr | 0.0047 | 0.0327 | 0.031 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0066 | 0.047 | 0.054 |
Trichomonas vaginalis | mercuric reductase, putative | 0.0016 | 0.0091 | 0.0102 |
Trypanosoma brucei | Adenine phosphoribosyltransferase, putative | 0.0015 | 0.0077 | 0.0025 |
Mycobacterium ulcerans | flavoprotein disulfide reductase | 0.0016 | 0.0091 | 0.0039 |
Echinococcus granulosus | g protein linked acetylcholine receptor gar 2a | 0.0066 | 0.047 | 0.054 |
Mycobacterium tuberculosis | Probable orotidine 5'-phosphate decarboxylase PyrF (OMP decarboxylase) (ompdecase) | 0.0034 | 0.0226 | 0.0185 |
Brugia malayi | Bloom's syndrome protein homolog | 0.0021 | 0.0128 | 0.0117 |
Loa Loa (eye worm) | hypothetical protein | 0.0066 | 0.047 | 0.0541 |
Brugia malayi | dihydrolipoyl dehydrogenase, mitochondrial precursor, putative | 0.0016 | 0.0091 | 0.0072 |
Plasmodium falciparum | thioredoxin reductase | 0.0047 | 0.0327 | 0.0295 |
Brugia malayi | hypothetical protein | 0.0066 | 0.047 | 0.054 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0066 | 0.047 | 0.054 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0029 | 0.019 | 0.0363 |
Echinococcus multilocularis | neuropeptide Y receptor | 0.0066 | 0.047 | 0.054 |
Echinococcus multilocularis | 7TM GPCR, rhodopsin | 0.0066 | 0.047 | 0.054 |
Echinococcus granulosus | neuropeptide receptor A26 | 0.0066 | 0.047 | 0.054 |
Echinococcus granulosus | pyroglutamylated rfamide peptide receptor | 0.0066 | 0.047 | 0.054 |
Echinococcus multilocularis | neuropeptides capa receptor | 0.0066 | 0.047 | 0.054 |
Echinococcus multilocularis | dihydrolipoamide dehydrogenase | 0.0016 | 0.0091 | 0.0072 |
Echinococcus multilocularis | peptide (allatostatin:somatostatin) | 0.0066 | 0.047 | 0.054 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0016 | 0.0091 | 0.0039 |
Loa Loa (eye worm) | 6-phosphofructokinase | 0.0109 | 0.0796 | 0.0943 |
Onchocerca volvulus | Dopamine\/Ecdysteroid receptor homolog | 0.0066 | 0.047 | 0.0488 |
Brugia malayi | hypothetical protein | 0.0508 | 0.3847 | 0.4714 |
Trichomonas vaginalis | DNA helicase recq, putative | 0.0021 | 0.0128 | 0.0199 |
Echinococcus granulosus | G protein coupled receptor 139 | 0.0066 | 0.047 | 0.054 |
Echinococcus multilocularis | fmrfamide receptor | 0.0066 | 0.047 | 0.054 |
Wolbachia endosymbiont of Brugia malayi | hypothetical protein | 0.0016 | 0.0089 | 0.0023 |
Onchocerca volvulus | Neuropeptide F receptor homolog | 0.0066 | 0.047 | 0.0488 |
Mycobacterium leprae | DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE | 0.012 | 0.0881 | 0.0999 |
Echinococcus multilocularis | uridine 5' monophosphate synthase | 0.0154 | 0.1145 | 0.1375 |
Schistosoma mansoni | biogenic amine (octopamine/dopamine) receptor | 0.0066 | 0.047 | 0.0578 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.012 | 0.0881 | 0.0999 |
Loa Loa (eye worm) | intermediate filament protein | 0.0027 | 0.0171 | 0.0171 |
Echinococcus multilocularis | hypoxanthine guanine phosphoribosyltransferase | 0.0015 | 0.0077 | 0.0055 |
Brugia malayi | Melatonin receptor type 1A | 0.0066 | 0.047 | 0.054 |
Loa Loa (eye worm) | hypothetical protein | 0.0066 | 0.047 | 0.0541 |
Loa Loa (eye worm) | hypothetical protein | 0.0066 | 0.047 | 0.0541 |
Loa Loa (eye worm) | hypothetical protein | 0.0066 | 0.047 | 0.0541 |
Brugia malayi | Cytochrome P450 family protein | 0.0012 | 0.0059 | 0.0033 |
Leishmania major | adenine phosphoribosyltransferase | 0.0015 | 0.0077 | 0.0025 |
Echinococcus multilocularis | g protein coupled receptor | 0.0066 | 0.047 | 0.054 |
Loa Loa (eye worm) | adenine phosphoribosyltransferase | 0.0015 | 0.0077 | 0.0055 |
Loa Loa (eye worm) | hypothetical protein | 0.0066 | 0.047 | 0.0541 |
Loa Loa (eye worm) | hypothetical protein | 0.0066 | 0.047 | 0.0541 |
Echinococcus granulosus | G protein coupled 5 hydroxytryptamine receptor | 0.0066 | 0.047 | 0.054 |
Entamoeba histolytica | pyrophosphate-dependent phosphofructokinase | 0.0029 | 0.019 | 0.2389 |
Echinococcus granulosus | thyrotropin releasing hormone receptor | 0.0066 | 0.047 | 0.054 |
Echinococcus granulosus | peptide allatostatin:somatostatin | 0.0066 | 0.047 | 0.054 |
Schistosoma mansoni | 6-phosphofructokinase | 0.0109 | 0.0796 | 0.0979 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0066 | 0.047 | 0.054 |
Onchocerca volvulus | 0.0066 | 0.047 | 0.0488 | |
Brugia malayi | alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase | 0.0012 | 0.0058 | 0.0031 |
Trypanosoma cruzi | dihydrofolate reductase-thymidylate synthase | 0.1313 | 1 | 1 |
Plasmodium falciparum | dihydrolipoyl dehydrogenase, mitochondrial | 0.0016 | 0.0091 | 0.0058 |
Brugia malayi | Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein | 0.0012 | 0.0058 | 0.0031 |
Loa Loa (eye worm) | 6-phosphofructokinase | 0.0109 | 0.0796 | 0.0943 |
Treponema pallidum | hypothetical protein | 0.0016 | 0.0089 | 0.1115 |
Echinococcus multilocularis | orexin receptor type 2 | 0.0066 | 0.047 | 0.054 |
Plasmodium falciparum | ATP-dependent 6-phosphofructokinase | 0.0029 | 0.019 | 0.0158 |
Mycobacterium tuberculosis | NAD(P)H quinone reductase LpdA | 0.012 | 0.0881 | 0.0999 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0012 | 0.0059 | 0.0033 |
Brugia malayi | Serotonin receptor | 0.0066 | 0.047 | 0.054 |
Echinococcus granulosus | g protein linked acetylcholine receptor gar 2a | 0.0066 | 0.047 | 0.054 |
Plasmodium falciparum | glutathione reductase | 0.0016 | 0.0091 | 0.0058 |
Trypanosoma brucei | deoxyuridine triphosphatase, putative | 0.0355 | 0.2676 | 0.2638 |
Loa Loa (eye worm) | hypothetical protein | 0.0066 | 0.047 | 0.0541 |
Loa Loa (eye worm) | hypothetical protein | 0.0066 | 0.047 | 0.0541 |
Plasmodium falciparum | glutathione reductase | 0.0047 | 0.0327 | 0.0295 |
Loa Loa (eye worm) | hypothetical protein | 0.0066 | 0.047 | 0.0541 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0066 | 0.047 | 0.054 |
Onchocerca volvulus | 0.0066 | 0.047 | 0.0488 | |
Onchocerca volvulus | 0.0066 | 0.047 | 0.0488 | |
Loa Loa (eye worm) | 5-hydroxytryptamine 2C receptor | 0.0066 | 0.047 | 0.0541 |
Schistosoma mansoni | peptide (FMRFamide/somatostatin)-like receptor | 0.0066 | 0.047 | 0.0578 |
Brugia malayi | dihydrofolate reductase family protein | 0.0462 | 0.3495 | 0.4279 |
Echinococcus multilocularis | O glycosyltransferase | 0.0041 | 0.028 | 0.0305 |
Loa Loa (eye worm) | hypothetical protein | 0.0066 | 0.047 | 0.0541 |
Mycobacterium tuberculosis | Probable orotate phosphoribosyltransferase PyrE (OPRT) (oprtase) | 0.0049 | 0.0338 | 0.0324 |
Loa Loa (eye worm) | hypothetical protein | 0.0066 | 0.047 | 0.0541 |
Loa Loa (eye worm) | hypothetical protein | 0.0066 | 0.047 | 0.0541 |
Echinococcus multilocularis | g protein coupled receptor | 0.0066 | 0.047 | 0.054 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0029 | 0.019 | 0.0363 |
Echinococcus granulosus | neuropeptide Y receptor | 0.0066 | 0.047 | 0.054 |
Loa Loa (eye worm) | melatonin receptor type 1A | 0.0066 | 0.047 | 0.0541 |
Echinococcus granulosus | growth hormone secretagogue receptor type 1 | 0.0066 | 0.047 | 0.054 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0066 | 0.047 | 0.054 |
Chlamydia trachomatis | fructose-6-phosphate phosphotransferase | 0.0029 | 0.019 | 0.0298 |
Wolbachia endosymbiont of Brugia malayi | orotidine-5'-phosphate decarboxylase | 0.0671 | 0.5097 | 1 |
Schistosoma mansoni | amine GPCR | 0.0066 | 0.047 | 0.0578 |
Toxoplasma gondii | pyruvate dehydrogenase complex subunit PDH-E3II | 0.0016 | 0.0091 | 0.0091 |
Loa Loa (eye worm) | hypothetical protein | 0.0066 | 0.047 | 0.0541 |
Echinococcus multilocularis | neuropeptide receptor | 0.0066 | 0.047 | 0.054 |
Mycobacterium tuberculosis | Dihydrofolate reductase DfrA (DHFR) (tetrahydrofolate dehydrogenase) | 0.0462 | 0.3495 | 0.4248 |
Onchocerca volvulus | 0.0066 | 0.047 | 0.0488 | |
Treponema pallidum | diphosphate--fructose-6-phosphate 1-phosphotransferase | 0.0109 | 0.0796 | 1 |
Brugia malayi | putative neuropeptide receptor NPR1 | 0.0066 | 0.047 | 0.054 |
Trypanosoma cruzi | orotidine-5-phosphate decarboxylase/orotate phosphoribosyltransferase, putative | 0.0154 | 0.1145 | 0.1098 |
Loa Loa (eye worm) | neuropeptide F receptor | 0.0066 | 0.047 | 0.0541 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0066 | 0.047 | 0.054 |
Entamoeba histolytica | phosphofructokinase, putative | 0.0109 | 0.0796 | 1 |
Trypanosoma brucei | hypoxanthine-guanine phosphoribosyltransferase | 0.0015 | 0.0077 | 0.0025 |
Trypanosoma cruzi | Adenine phosphoribosyltransferase, putative | 0.0015 | 0.0077 | 0.0025 |
Loa Loa (eye worm) | hypothetical protein | 0.0066 | 0.047 | 0.0541 |
Mycobacterium ulcerans | hypoxanthine-guanine phosphoribosyltransferase Hpt | 0.0015 | 0.0077 | 0.0022 |
Onchocerca volvulus | 0.0066 | 0.047 | 0.0488 | |
Brugia malayi | Tachykinin-like peptides receptor 99D | 0.0066 | 0.047 | 0.054 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0066 | 0.047 | 0.054 |
Trypanosoma cruzi | dihydrolipoyl dehydrogenase, putative | 0.0016 | 0.0091 | 0.0039 |
Echinococcus multilocularis | musashi | 0.0027 | 0.0171 | 0.017 |
Mycobacterium tuberculosis | Probable reductase | 0.0108 | 0.0789 | 0.0885 |
Echinococcus multilocularis | dihydrofolate reductase | 0.0462 | 0.3495 | 0.4279 |
Treponema pallidum | adenine phosphoribosyltransferase | 0.0015 | 0.0077 | 0.0971 |
Mycobacterium ulcerans | dihydrofolate reductase DfrA | 0.0462 | 0.3495 | 0.4261 |
Leishmania major | cytochrome p450-like protein | 0.0012 | 0.0059 | 0.0007 |
Schistosoma mansoni | hypoxanthine-guanine phosphoribosyltransferase | 0.0015 | 0.0077 | 0.0095 |
Brugia malayi | RE15519p | 0.0066 | 0.047 | 0.054 |
Echinococcus granulosus | dihydrofolate reductase | 0.0462 | 0.3495 | 0.4279 |
Schistosoma mansoni | orotidine 5'-phosphate decarboxylase | 0.0154 | 0.1145 | 0.141 |
Plasmodium vivax | orotate phosphoribosyltransferase, putative | 0.0049 | 0.0338 | 0.0264 |
Brugia malayi | ORL1-like opioid receptor | 0.0066 | 0.047 | 0.054 |
Echinococcus granulosus | 7tm_1 domain containing protein | 0.0066 | 0.047 | 0.054 |
Schistosoma mansoni | intermediate filament proteins | 0.0027 | 0.0171 | 0.021 |
Wolbachia endosymbiont of Brugia malayi | dihydrolipoamide dehydrogenase E3 component | 0.0016 | 0.0091 | 0.0027 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0016 | 0.0091 | 0.0039 |
Schistosoma mansoni | bifunctional dihydrofolate reductase-thymidylate synthase | 0.1068 | 0.8124 | 1 |
Onchocerca volvulus | 0.0066 | 0.047 | 0.0488 | |
Echinococcus granulosus | orexin receptor type 2 | 0.0066 | 0.047 | 0.054 |
Schistosoma mansoni | hypothetical protein | 0.0066 | 0.047 | 0.0578 |
Echinococcus granulosus | g protein coupled receptor | 0.0066 | 0.047 | 0.054 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0029 | 0.019 | 0.0363 |
Mycobacterium tuberculosis | Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) | 0.0109 | 0.0796 | 0.0893 |
Mycobacterium tuberculosis | Probable NADH dehydrogenase Ndh | 0.0108 | 0.0789 | 0.0885 |
Echinococcus granulosus | hypoxanthine guanine phosphoribosyltransferase | 0.0015 | 0.0077 | 0.0055 |
Loa Loa (eye worm) | hypothetical protein | 0.0066 | 0.047 | 0.0541 |
Echinococcus multilocularis | neuropeptide receptor A26 | 0.0066 | 0.047 | 0.054 |
Toxoplasma gondii | orotate phosphoribosyltransferase | 0.0049 | 0.0338 | 0.0338 |
Onchocerca volvulus | 0.0066 | 0.047 | 0.0488 | |
Brugia malayi | hypothetical protein | 0.0066 | 0.047 | 0.054 |
Loa Loa (eye worm) | thymidylate synthase | 0.1068 | 0.8124 | 1 |
Brugia malayi | thymidylate synthase | 0.1068 | 0.8124 | 1 |
Schistosoma mansoni | peptide (allatostatin)-like receptor | 0.0066 | 0.047 | 0.0578 |
Onchocerca volvulus | 0.0066 | 0.047 | 0.0488 | |
Trypanosoma cruzi | dihydrofolate reductase-thymidylate synthase, putative | 0.0508 | 0.3847 | 0.3814 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0061 | 0.0035 |
Echinococcus multilocularis | serotonin receptor | 0.0066 | 0.047 | 0.054 |
Loa Loa (eye worm) | hypothetical protein | 0.0066 | 0.047 | 0.0541 |
Schistosoma mansoni | amine GPCR | 0.0066 | 0.047 | 0.0578 |
Schistosoma mansoni | alpha-1 adrenergic receptor | 0.0066 | 0.047 | 0.0578 |
Echinococcus granulosus | dihydrolipoamide dehydrogenase | 0.0016 | 0.0091 | 0.0072 |
Wolbachia endosymbiont of Brugia malayi | orotate phosphoribosyltransferase | 0.0049 | 0.0338 | 0.0519 |
Treponema pallidum | hypothetical protein | 0.0015 | 0.0077 | 0.0971 |
Brugia malayi | Phosphoribosyl transferase domain containing protein | 0.0015 | 0.0077 | 0.0055 |
Echinococcus multilocularis | g-protein coupled receptor | 0.0066 | 0.047 | 0.054 |
Echinococcus multilocularis | G protein coupled 5 hydroxytryptamine receptor | 0.0066 | 0.047 | 0.054 |
Brugia malayi | orotate phosphoribosyltransferase family protein | 0.0154 | 0.1145 | 0.1375 |
Plasmodium vivax | hypoxanthine-guanine phosphoribosyltransferase, putative | 0.0015 | 0.0077 | 0.0002 |
Schistosoma mansoni | neuropeptide receptor | 0.0066 | 0.047 | 0.0578 |
Brugia malayi | 6-phosphofructokinase | 0.0109 | 0.0796 | 0.0943 |
Schistosoma mansoni | peptide (FMRFamide/neurokinin-3)-like receptor | 0.0066 | 0.047 | 0.0578 |
Schistosoma mansoni | opsin-like receptor | 0.0066 | 0.047 | 0.0578 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0061 | 0.0035 |
Loa Loa (eye worm) | hypothetical protein | 0.0066 | 0.047 | 0.0541 |
Loa Loa (eye worm) | G-protein-linked acetylcholine receptor protein 2 | 0.0066 | 0.047 | 0.0541 |
Mycobacterium tuberculosis | Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot | 0.0016 | 0.0091 | 0.0017 |
Mycobacterium tuberculosis | Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB | 0.0108 | 0.0789 | 0.0885 |
Mycobacterium ulcerans | thymidylate synthase | 0.1068 | 0.8124 | 1 |
Schistosoma mansoni | lamin | 0.0027 | 0.0171 | 0.021 |
Trypanosoma brucei | dihydrofolate reductase-thymidylate synthase | 0.1313 | 1 | 1 |
Entamoeba histolytica | recQ family helicase, putative | 0.0011 | 0.0052 | 0.0659 |
Trypanosoma cruzi | Adenine phosphoribosyltransferase, putative | 0.0015 | 0.0077 | 0.0025 |
Schistosoma mansoni | dihydrofolate reductase | 0.0462 | 0.3495 | 0.4303 |
Mycobacterium tuberculosis | Putative ferredoxin reductase | 0.0108 | 0.0789 | 0.0885 |
Plasmodium falciparum | ATP-dependent 6-phosphofructokinase | 0.0029 | 0.019 | 0.0158 |
Schistosoma mansoni | growth hormone secretagogue receptor | 0.0066 | 0.047 | 0.0578 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0016 | 0.0091 | 0.0039 |
Schistosoma mansoni | thyrotropin-releasing hormone receptor | 0.0066 | 0.047 | 0.0578 |
Echinococcus multilocularis | alpha 1A adrenergic receptor | 0.0066 | 0.047 | 0.054 |
Brugia malayi | G-protein-linked acetylcholine receptor protein 2, putative | 0.0066 | 0.047 | 0.054 |
Mycobacterium leprae | PROBABLE OROTATE PHOSPHORIBOSYLTRANSFERASE PYRE (OPRT) (OPRTASE) | 0.0049 | 0.0338 | 0.0324 |
Mycobacterium ulcerans | bifunctional pyrimidine regulatory protein PyrR/uracil phosphoribosyltransferase | 0.0015 | 0.0077 | 0.0022 |
Schistosoma mansoni | ancient conserved domain protein 2 (cyclin m2) | 0.0066 | 0.047 | 0.0578 |
Loa Loa (eye worm) | hypothetical protein | 0.0066 | 0.047 | 0.0541 |
Trypanosoma brucei | cytochrome P450, putative | 0.0012 | 0.0059 | 0.0007 |
Toxoplasma gondii | O-linked N-acetylglucosamine transferase | 0.0041 | 0.0276 | 0.0276 |
Brugia malayi | Serotonin receptor | 0.0066 | 0.047 | 0.054 |
Loa Loa (eye worm) | hypothetical protein | 0.0066 | 0.047 | 0.0541 |
Loa Loa (eye worm) | thioredoxin reductase | 0.0047 | 0.0327 | 0.0364 |
Brugia malayi | hypothetical protein | 0.0066 | 0.047 | 0.054 |
Mycobacterium tuberculosis | Probable dehydrogenase | 0.0108 | 0.0789 | 0.0885 |
Schistosoma mansoni | dihydrolipoamide dehydrogenase | 0.0016 | 0.0091 | 0.0112 |
Brugia malayi | hypothetical protein | 0.0066 | 0.047 | 0.054 |
Leishmania major | xanthine phosphoribosyltransferase | 0.0015 | 0.0077 | 0.0025 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0066 | 0.047 | 0.0578 |
Mycobacterium tuberculosis | Hypothetical protein | 0.0508 | 0.3847 | 0.4685 |
Loa Loa (eye worm) | hypothetical protein | 0.0066 | 0.047 | 0.0541 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0066 | 0.047 | 0.054 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0066 | 0.047 | 0.054 |
Treponema pallidum | hypothetical protein | 0.0016 | 0.0089 | 0.1115 |
Loa Loa (eye worm) | hypothetical protein | 0.0066 | 0.047 | 0.0541 |
Chlamydia trachomatis | dihydrolipoyl dehydrogenase | 0.0016 | 0.0091 | 0.0007 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0066 | 0.047 | 0.054 |
Echinococcus granulosus | neuropeptide receptor | 0.0066 | 0.047 | 0.054 |
Echinococcus multilocularis | G protein coupled receptor 139 | 0.0066 | 0.047 | 0.054 |
Loa Loa (eye worm) | CYP4Cod1 | 0.0012 | 0.0059 | 0.0033 |
Loa Loa (eye worm) | hypothetical protein | 0.0066 | 0.047 | 0.0541 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0066 | 0.047 | 0.054 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0066 | 0.047 | 0.0578 |
Schistosoma mansoni | amine GPCR | 0.0066 | 0.047 | 0.0578 |
Onchocerca volvulus | 0.0066 | 0.047 | 0.0488 | |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0095 | 0.0077 |
Brugia malayi | G protein-coupled receptor | 0.0066 | 0.047 | 0.054 |
Loa Loa (eye worm) | cytoplasmic intermediate filament protein | 0.0014 | 0.0076 | 0.0053 |
Treponema pallidum | hypothetical protein | 0.0016 | 0.0089 | 0.1115 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0066 | 0.047 | 0.0578 |
Schistosoma mansoni | biogenic amine (5HT) receptor | 0.0066 | 0.047 | 0.0578 |
Brugia malayi | AKH receptor | 0.0066 | 0.047 | 0.054 |
Schistosoma mansoni | blooms syndrome DNA helicase | 0.0017 | 0.0094 | 0.0115 |
Loa Loa (eye worm) | gonadotropin-releasing hormone receptor 2 | 0.0066 | 0.047 | 0.0541 |
Schistosoma mansoni | muscarinic acetylcholine (GAR) receptor | 0.0066 | 0.047 | 0.0578 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0016 | 0.0091 | 0.0039 |
Giardia lamblia | Guanine phosphoribosyltransferase | 0.0015 | 0.0077 | 0.1827 |
Echinococcus granulosus | somatostatin receptor | 0.0066 | 0.047 | 0.054 |
Brugia malayi | follicle stimulating hormone receptor | 0.0294 | 0.2215 | 0.2697 |
Schistosoma mansoni | biogenic amine receptor | 0.0066 | 0.047 | 0.0578 |
Trypanosoma brucei | orotidine-5-phosphate decarboxylase/orotate phosphoribosyltransferase, putative | 0.0154 | 0.1145 | 0.1098 |
Loa Loa (eye worm) | hypothetical protein | 0.0066 | 0.047 | 0.0541 |
Echinococcus granulosus | lamin | 0.0027 | 0.0171 | 0.017 |
Schistosoma mansoni | neuropeptide receptor | 0.0066 | 0.047 | 0.0578 |
Trypanosoma brucei | ATP-dependent 6-phosphofructokinase, glycosomal | 0.0109 | 0.0796 | 0.0747 |
Leishmania major | ATP-dependent phosphofructokinase | 0.0109 | 0.0796 | 0.0747 |
Echinococcus multilocularis | G-protein coupled receptor, putative | 0.0066 | 0.047 | 0.054 |
Plasmodium falciparum | bifunctional dihydrofolate reductase-thymidylate synthase | 0.1313 | 1 | 1 |
Onchocerca volvulus | 0.0066 | 0.047 | 0.0488 | |
Loa Loa (eye worm) | hypothetical protein | 0.0066 | 0.047 | 0.0541 |
Echinococcus granulosus | uridine 5' monophosphate synthase | 0.0154 | 0.1145 | 0.1375 |
Echinococcus multilocularis | growth hormone secretagogue receptor type 1 | 0.0066 | 0.047 | 0.054 |
Brugia malayi | hypothetical protein | 0.0066 | 0.047 | 0.054 |
Onchocerca volvulus | 0.0066 | 0.047 | 0.0488 | |
Toxoplasma gondii | phosphofructokinase domain-containing protein | 0.0029 | 0.019 | 0.019 |
Mycobacterium ulcerans | dihydrolipoamide dehydrogenase, LpdB | 0.0016 | 0.0091 | 0.0039 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Delta MST (functional) | = 0 day | Antimalarial effect against Trophozoite-induced P. berghei in mice after subcutaneous administration dose of 640 mg/kg; 5 toxic deaths after 2-5 days of injection | ChEMBL. | 6227747 |
Delta MST (functional) | = 0 day | Antimalarial effect against Trophozoite-induced P. berghei in mice after subcutaneous administration dose of 320 mg/kg; 1 survived after 60 days of postinfection | ChEMBL. | 6227747 |
Delta MST (functional) | = 0.9 day | Antimalarial effect against Trophozoite-induced P. berghei in mice after subcutaneous administration dose of 40 mg/kg | ChEMBL. | 6227747 |
Delta MST (functional) | = 0.9 day | Antimalarial effect against Trophozoite-induced P. berghei in mice after subcutaneous administration dose of 10 mg/kg | ChEMBL. | 6227747 |
Delta MST (functional) | = 0.9 day | Antimalarial effect against Trophozoite-induced P. berghei in mice after subcutaneous administration dose of 40 mg/kg | ChEMBL. | 6227747 |
Delta MST (functional) | = 0.9 day | Antimalarial effect against Trophozoite-induced P. berghei in mice after subcutaneous administration dose of 10 mg/kg | ChEMBL. | 6227747 |
Delta MST (functional) | = 1.3 day | Antimalarial effect against trophozoite induced Plasmodium berghei in mice after subcutaneous administration dose of 20 mg/kg | ChEMBL. | 6227747 |
Delta MST (functional) | = 1.3 day | Antimalarial effect against trophozoite induced Plasmodium berghei in mice after subcutaneous administration dose of 20 mg/kg | ChEMBL. | 6227747 |
Delta MST (functional) | = 3.7 day | Antimalarial effect against Trophozoite-induced P. berghei in mice after subcutaneous administration dose of 80 mg/kg | ChEMBL. | 6227747 |
Delta MST (functional) | = 3.7 day | Antimalarial effect against Trophozoite-induced P. berghei in mice after subcutaneous administration dose of 80 mg/kg | ChEMBL. | 6227747 |
Delta MST (functional) | = 4.1 day | Antimalarial effect against Trophozoite-induced P. berghei in mice after subcutaneous administration dose of 80 mg/kg | ChEMBL. | 6227747 |
Delta MST (functional) | = 4.1 day | Antimalarial effect against Trophozoite-induced P. berghei in mice after subcutaneous administration dose of 80 mg/kg | ChEMBL. | 6227747 |
Delta MST (functional) | = 8.3 day | Antimalarial effect against Trophozoite-induced P. berghei in mice after subcutaneous administration dose of 80 mg/kg | ChEMBL. | 6227747 |
Delta MST (functional) | = 8.3 day | Antimalarial effect against Trophozoite-induced P. berghei in mice after subcutaneous administration dose of 80 mg/kg | ChEMBL. | 6227747 |
Delta MST (functional) | = 11.7 day | Antimalarial effect against Trophozoite-induced P. berghei in mice after subcutaneous administration dose of 320 mg/kg; 1 survived after 60 days of postinfection | ChEMBL. | 6227747 |
Delta MST (functional) | = 11.7 day | Antimalarial effect against Trophozoite-induced P. berghei in mice after subcutaneous administration dose of 320 mg/kg; 1 survived after 60 days of postinfection | ChEMBL. | 6227747 |
Delta MST (functional) | = 11.9 day | Antimalarial effect against Trophozoite-induced P. berghei in mice after subcutaneous administration dose of 320 mg/kg; 4 toxic deaths after 2-5 days of injection | ChEMBL. | 6227747 |
Delta MST (functional) | = 11.9 day | Antimalarial effect against Trophozoite-induced P. berghei in mice after subcutaneous administration dose of 320 mg/kg; 4 toxic deaths after 2-5 days of injection | ChEMBL. | 6227747 |
ID50 (functional) | = 0.00000019 M | Molar concentration required to reduce the number of L1210 cells by 50% after incubation for 2 days | ChEMBL. | 6227747 |
ID50 (functional) | = 0.00000019 M | Molar concentration required to reduce the number of L1210 cells by 50% after incubation for 2 days | ChEMBL. | 6227747 |
ID50 (functional) | = 0.0000003 M | Molar concentration required to reduce the number of L1210 cells by 50% after incubation for 2 days | ChEMBL. | 6227747 |
ID50 (functional) | = 0.0000003 M | Molar concentration required to reduce the number of L1210 cells by 50% after incubation for 2 days | ChEMBL. | 6227747 |
log(1/I50) (binding) | = 7.3 | Inhibition of dihydrofolate reductase in human acute lymphocytic leukemia cells | ChEMBL. | 110930 |
SD90 (functional) | > 15.1 mg kg-1 day-1 | Daily dose required for 90% parasitaemia in trophozoite induced P. berghei in 21 mice | ChEMBL. | 6227747 |
SD90 (functional) | > 15.1 mg kg-1 day-1 | Daily dose required for 90% parasitaemia in trophozoite induced P. berghei in 21 mice | ChEMBL. | 6227747 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
2 literature references were collected for this gene.