Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trypanosoma brucei | mitogen activated protein kinase 4, putative | 0.005 | 0.0532 | 0.1024 |
Schistosoma mansoni | ran | 0.0022 | 0.0105 | 0.0105 |
Leishmania major | mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 | 0.005 | 0.0532 | 0.1024 |
Loa Loa (eye worm) | CMGC/MAPK/ERK1 protein kinase | 0.005 | 0.0532 | 0.119 |
Brugia malayi | 3-hydroxyacyl-CoA dehydrogenase type II | 0.0056 | 0.0626 | 0.2269 |
Schistosoma mansoni | 3-hydroxyacyl-CoA dehydrogenase | 0.0056 | 0.0626 | 0.0626 |
Brugia malayi | AMP-binding enzyme family protein | 0.0023 | 0.0131 | 0.0474 |
Loa Loa (eye worm) | GTP-binding nuclear protein RAN/TC4 | 0.0022 | 0.0105 | 0.0235 |
Entamoeba histolytica | hypothetical protein | 0.0036 | 0.0317 | 0.1819 |
Echinococcus multilocularis | GPCR, family 2 | 0.0063 | 0.0724 | 0.0724 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0023 | 0.0131 | 0.5 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0023 | 0.0131 | 0.0419 |
Brugia malayi | RNA binding protein | 0.0189 | 0.2611 | 0.9465 |
Echinococcus granulosus | lamin | 0.0028 | 0.0194 | 0.0194 |
Schistosoma mansoni | tar DNA-binding protein | 0.0189 | 0.2611 | 0.2611 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0023 | 0.0131 | 0.0062 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0031 | 0.0244 | 0.0884 |
Echinococcus granulosus | 3 hydroxyacyl coenzyme A dehydrogenase type 2 | 0.0056 | 0.0626 | 0.0626 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0039 | 0.0363 | 0.3614 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0194 | 0.0435 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0031 | 0.0244 | 0.0244 |
Loa Loa (eye worm) | hypothetical protein | 0.0099 | 0.127 | 0.2844 |
Mycobacterium ulcerans | long-chain fatty-acid CoA ligase | 0.0023 | 0.0131 | 0.0419 |
Schistosoma mansoni | hypothetical protein | 0.0041 | 0.0398 | 0.0398 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0031 | 0.0244 | 0.0546 |
Trypanosoma brucei | protein kinase, putative | 0.005 | 0.0532 | 0.1024 |
Schistosoma mansoni | hypothetical protein | 0.0041 | 0.0398 | 0.0398 |
Mycobacterium ulcerans | long-chain-fatty-acid--CoA ligase | 0.0023 | 0.0131 | 0.0419 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0028 | 0.0194 | 0.0435 |
Trypanosoma brucei | mitochondrial DNA polymerase beta | 0.03 | 0.4271 | 1 |
Echinococcus granulosus | Protein patched homolog 1 | 0.0043 | 0.0421 | 0.0421 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0093 | 0.1177 | 0.4268 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0131 | 0.0293 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0031 | 0.0244 | 0.0546 |
Brugia malayi | AMP-binding enzyme family protein | 0.0023 | 0.0131 | 0.0474 |
Onchocerca volvulus | 0.0031 | 0.0244 | 0.5997 | |
Brugia malayi | AMP-binding enzyme family protein | 0.0023 | 0.0131 | 0.0474 |
Entamoeba histolytica | hypothetical protein | 0.0036 | 0.0317 | 0.1819 |
Brugia malayi | nuclear receptor RXR | 0.0016 | 0.0026 | 0.0095 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0031 | 0.0244 | 0.0244 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.0142 | 0.1907 | 0.4324 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0043 | 0.0421 | 0.4428 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0031 | 0.0244 | 0.0884 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0016 | 0.0026 | 0.0095 |
Brugia malayi | GTP-binding nuclear protein RAN/TC4 | 0.0022 | 0.0105 | 0.0381 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0016 | 0.0026 | 0.0095 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0031 | 0.0244 | 0.0244 |
Brugia malayi | cytoplasmic intermediate filament protein | 0.0015 | 0.0003 | 0.0011 |
Echinococcus multilocularis | geminin | 0.0173 | 0.2372 | 0.2372 |
Onchocerca volvulus | Heterochromatin protein 1 homolog | 0.0039 | 0.0363 | 0.8916 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0028 | 0.0194 | 0.0705 |
Echinococcus multilocularis | nuclear receptor subfamily 1 group D | 0.0016 | 0.0026 | 0.0026 |
Schistosoma mansoni | hypothetical protein | 0.0041 | 0.0398 | 0.0398 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0031 | 0.0244 | 0.0884 |
Trypanosoma brucei | mitochondrial DNA polymerase beta-PAK | 0.0142 | 0.1907 | 0.4324 |
Toxoplasma gondii | hypothetical protein | 0.0048 | 0.0506 | 0.9406 |
Trichomonas vaginalis | CMGC family protein kinase | 0.005 | 0.0532 | 0.5984 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.012 | 0.1576 | 0.353 |
Entamoeba histolytica | acyl-coA synthetase, putative | 0.0023 | 0.0131 | 0.0221 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0031 | 0.0244 | 0.0884 |
Brugia malayi | hypothetical protein | 0.0016 | 0.0026 | 0.0095 |
Schistosoma mansoni | hypothetical protein | 0.0063 | 0.0724 | 0.0724 |
Schistosoma mansoni | hypothetical protein | 0.0063 | 0.0724 | 0.0724 |
Echinococcus granulosus | nuclear receptor subfamily 1 group D | 0.0016 | 0.0026 | 0.0026 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0031 | 0.0244 | 0.0546 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0031 | 0.0244 | 0.0884 |
Echinococcus multilocularis | sterol regulatory element binding protein | 0.0043 | 0.0421 | 0.0421 |
Brugia malayi | ecdysteroid receptor | 0.0031 | 0.0244 | 0.0884 |
Schistosoma mansoni | niemann-pick C1 (NPC1) | 0.0101 | 0.1293 | 0.1293 |
Echinococcus multilocularis | microtubule associated protein 2 | 0.0682 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0244 | 0.0546 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0023 | 0.0131 | 0.0419 |
Trichomonas vaginalis | chromobox protein, putative | 0.0069 | 0.0818 | 1 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0063 | 0.0724 | 0.2624 |
Trichomonas vaginalis | CMGC family protein kinase | 0.005 | 0.0532 | 0.5984 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0031 | 0.0244 | 0.0244 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0063 | 0.0724 | 0.0724 |
Entamoeba histolytica | hypothetical protein | 0.0036 | 0.0317 | 0.1819 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0187 | 0.0418 |
Leishmania major | mitogen activated protein kinase, putative,map kinase, putative | 0.005 | 0.0532 | 0.1024 |
Echinococcus granulosus | chromobox protein 1 | 0.0069 | 0.0818 | 0.0818 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0031 | 0.0244 | 0.0244 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0031 | 0.0244 | 0.0244 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.0042 | 0.0413 | 0.074 |
Echinococcus multilocularis | tar DNA binding protein | 0.0189 | 0.2611 | 0.2611 |
Schistosoma mansoni | hypothetical protein | 0.0173 | 0.2372 | 0.2372 |
Brugia malayi | intermediate filament protein | 0.0028 | 0.0194 | 0.0705 |
Loa Loa (eye worm) | TAR-binding protein | 0.0189 | 0.2611 | 0.5847 |
Schistosoma mansoni | hypothetical protein | 0.0136 | 0.1817 | 0.1817 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0023 | 0.0131 | 0.5 |
Schistosoma mansoni | importin beta-1 | 0.0029 | 0.0221 | 0.0221 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0027 | 0.0193 | 0.1236 |
Loa Loa (eye worm) | hypothetical protein | 0.0063 | 0.0724 | 0.1621 |
Trichomonas vaginalis | CMGC family protein kinase | 0.005 | 0.0532 | 0.5984 |
Chlamydia trachomatis | acylglycerophosphoethanolamine acyltransferase | 0.0017 | 0.0043 | 0.5 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0036 | 0.0317 | 0.0317 |
Leishmania major | importin beta-1 subunit, putative | 0.0024 | 0.0138 | 0.0079 |
Brugia malayi | steroid hormone receptor | 0.0031 | 0.0244 | 0.0884 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0199 | 0.2759 | 1 |
Echinococcus multilocularis | 3 hydroxyacyl coenzyme A dehydrogenase type 2 | 0.0056 | 0.0626 | 0.0626 |
Trichomonas vaginalis | Importin beta-1 subunit, putative | 0.0024 | 0.0138 | 0.0461 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0063 | 0.0724 | 0.0724 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta, putative | 0.03 | 0.4271 | 1 |
Leishmania major | mitochondrial DNA polymerase beta | 0.03 | 0.4271 | 1 |
Schistosoma mansoni | intermediate filament proteins | 0.0028 | 0.0194 | 0.0194 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.0031 | 0.0244 | 0.5997 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0031 | 0.0244 | 0.0244 |
Toxoplasma gondii | HEAT repeat-containing protein | 0.0029 | 0.0221 | 0.2716 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0063 | 0.0724 | 0.1621 |
Echinococcus multilocularis | mitogen activated protein kinase | 0.005 | 0.0532 | 0.0532 |
Loa Loa (eye worm) | RNA binding protein | 0.0189 | 0.2611 | 0.5847 |
Trypanosoma cruzi | DNA polymerase beta thumb, putative | 0.0042 | 0.0413 | 0.074 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0244 | 0.0546 |
Brugia malayi | hypothetical protein | 0.0016 | 0.0026 | 0.0095 |
Plasmodium vivax | GTP-binding nuclear protein RAN/TC4, putative | 0.0022 | 0.0105 | 0.35 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0016 | 0.0026 | 0.0026 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0031 | 0.0244 | 0.0244 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0031 | 0.0244 | 0.0884 |
Brugia malayi | MH2 domain containing protein | 0.012 | 0.1576 | 0.5714 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0244 | 0.0546 |
Schistosoma mansoni | hypothetical protein | 0.0063 | 0.0724 | 0.0724 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0199 | 0.2759 | 0.6178 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0031 | 0.0244 | 0.0244 |
Onchocerca volvulus | Bile acid receptor homolog | 0.0031 | 0.0244 | 0.5997 |
Loa Loa (eye worm) | intermediate filament protein | 0.0028 | 0.0194 | 0.0435 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0043 | 0.0096 |
Schistosoma mansoni | ecdysone-induced protein 78c (dr-78) | 0.0016 | 0.0026 | 0.0026 |
Echinococcus granulosus | chromobox protein 1 | 0.0069 | 0.0818 | 0.0818 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0031 | 0.0244 | 0.0244 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0023 | 0.0131 | 0.0419 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0136 | 0.1817 | 0.6586 |
Plasmodium vivax | importin-beta 2, putative | 0.0029 | 0.0221 | 1 |
Trypanosoma cruzi | mitogen-activated protein kinase 11, putative | 0.005 | 0.0532 | 0.1024 |
Schistosoma mansoni | hypothetical protein | 0.0173 | 0.2372 | 0.2372 |
Loa Loa (eye worm) | heterochromatin protein 1 | 0.0069 | 0.0818 | 0.1831 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0063 | 0.0724 | 0.0724 |
Entamoeba histolytica | Niemann-Pick C1 protein, putative | 0.0099 | 0.127 | 1 |
Schistosoma mansoni | lamin | 0.0028 | 0.0194 | 0.0194 |
Echinococcus granulosus | geminin | 0.0173 | 0.2372 | 0.2372 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0063 | 0.0724 | 0.0724 |
Echinococcus multilocularis | snurportin 1 | 0.0313 | 0.4466 | 0.4466 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta, putative | 0.03 | 0.4271 | 1 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0063 | 0.0724 | 0.2624 |
Schistosoma mansoni | lamin | 0.0028 | 0.0194 | 0.0194 |
Schistosoma mansoni | tar DNA-binding protein | 0.0189 | 0.2611 | 0.2611 |
Brugia malayi | CHE-14 protein | 0.0043 | 0.0421 | 0.1525 |
Schistosoma mansoni | chromobox protein | 0.0069 | 0.0818 | 0.0818 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0023 | 0.0131 | 0.0419 |
Loa Loa (eye worm) | hypothetical protein | 0.0199 | 0.2759 | 0.6178 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0199 | 0.2759 | 1 |
Echinococcus granulosus | GTP binding nuclear protein Ran | 0.0022 | 0.0105 | 0.0105 |
Onchocerca volvulus | 0.003 | 0.0237 | 0.5833 | |
Loa Loa (eye worm) | nucleolar RNA-associated protein alpha | 0.0313 | 0.4466 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0136 | 0.1817 | 0.4069 |
Echinococcus multilocularis | expressed conserved protein | 0.0093 | 0.118 | 0.118 |
Echinococcus multilocularis | protein dispatched 1 | 0.0049 | 0.0511 | 0.0511 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0031 | 0.0244 | 0.0884 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0031 | 0.0244 | 0.0244 |
Loa Loa (eye worm) | 3-hydroxyacyl-CoA dehydrogenase type II | 0.0053 | 0.0569 | 0.1274 |
Trypanosoma cruzi | mitogen activated protein kinase 4, putative | 0.005 | 0.0532 | 0.1024 |
Echinococcus granulosus | lamin dm0 | 0.0028 | 0.0194 | 0.0194 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.0363 | 0.0812 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0031 | 0.0244 | 0.0244 |
Echinococcus granulosus | mitogen activated protein kinase 3 | 0.005 | 0.0532 | 0.0532 |
Schistosoma mansoni | microtubule-associated protein tau | 0.0682 | 1 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0063 | 0.0724 | 0.0724 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0244 | 0.0546 |
Echinococcus granulosus | sterol regulatory element binding protein | 0.0043 | 0.0421 | 0.0421 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0036 | 0.0317 | 0.0317 |
Leishmania major | mitochondrial DNA polymerase beta-PAK, putative | 0.0142 | 0.1907 | 0.4324 |
Brugia malayi | Niemann-Pick C1 protein precursor | 0.0099 | 0.127 | 0.4603 |
Echinococcus multilocularis | lamin dm0 | 0.0028 | 0.0194 | 0.0194 |
Trypanosoma brucei | DNA polymerase beta thumb, putative | 0.0042 | 0.0413 | 0.074 |
Schistosoma mansoni | chromobox protein | 0.0069 | 0.0818 | 0.0818 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0031 | 0.0244 | 0.0546 |
Brugia malayi | Heterochromatin protein 1 | 0.0069 | 0.0818 | 0.2964 |
Trypanosoma cruzi | mitogen-activated protein kinase 11, putative | 0.005 | 0.0532 | 0.1024 |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.0026 | 0.0058 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0031 | 0.0244 | 0.0244 |
Echinococcus multilocularis | musashi | 0.0028 | 0.0194 | 0.0194 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0093 | 0.1177 | 0.1177 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0043 | 0.0096 |
Leishmania major | 3-oxoacyl-(acyl-carrier protein) reductase, putative | 0.0056 | 0.0626 | 0.125 |
Brugia malayi | MAP kinase sur-1 | 0.005 | 0.0532 | 0.1927 |
Mycobacterium ulcerans | hypothetical protein | 0.0158 | 0.2147 | 1 |
Mycobacterium tuberculosis | Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) | 0.0017 | 0.0043 | 0.0067 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0031 | 0.0244 | 0.0244 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0043 | 0.0096 |
Loa Loa (eye worm) | cytoplasmic intermediate filament protein | 0.0015 | 0.0003 | 0.0007 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0244 | 0.0546 |
Schistosoma mansoni | serine/threonine protein kinase | 0.005 | 0.0532 | 0.0532 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0031 | 0.0244 | 0.0244 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0031 | 0.0244 | 0.0546 |
Echinococcus multilocularis | GTP binding nuclear protein Ran | 0.0022 | 0.0105 | 0.0105 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0244 | 0.0546 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0244 | 0.0546 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.0031 | 0.0244 | 0.5997 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0031 | 0.0244 | 0.0244 |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.0026 | 0.0058 |
Brugia malayi | TAR-binding protein | 0.0189 | 0.2611 | 0.9465 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0043 | 0.0096 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0039 | 0.0363 | 0.3614 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0027 | 0.0193 | 0.1236 |
Echinococcus granulosus | Niemann Pick C1 protein | 0.0099 | 0.127 | 0.127 |
Brugia malayi | nuclear receptor NHR-88 | 0.0031 | 0.0244 | 0.0884 |
Brugia malayi | chromobox protein homolog 3 | 0.0039 | 0.0363 | 0.1315 |
Echinococcus granulosus | importin subunit beta 1 | 0.0029 | 0.0221 | 0.0221 |
Echinococcus multilocularis | Niemann Pick C1 protein | 0.0142 | 0.1908 | 0.1908 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0031 | 0.0244 | 0.0244 |
Schistosoma mansoni | coup transcription factor | 0.0031 | 0.0244 | 0.0244 |
Echinococcus multilocularis | lamin | 0.0028 | 0.0194 | 0.0194 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0131 | 0.0293 |
Echinococcus granulosus | tar DNA binding protein | 0.0189 | 0.2611 | 0.2611 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0031 | 0.0244 | 0.0244 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0093 | 0.1177 | 0.1177 |
Mycobacterium tuberculosis | Probable short-chain type dehydrogenase/reductase | 0.0056 | 0.0626 | 0.282 |
Echinococcus granulosus | FTZ F1 alpha | 0.0031 | 0.0244 | 0.0244 |
Trichomonas vaginalis | chromobox protein, putative | 0.0042 | 0.0407 | 0.4233 |
Echinococcus multilocularis | mitogen activated protein kinase 3 | 0.005 | 0.0532 | 0.0532 |
Onchocerca volvulus | Heterochromatin protein 1 homolog | 0.0042 | 0.0407 | 1 |
Echinococcus granulosus | expressed conserved protein | 0.0093 | 0.118 | 0.118 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0093 | 0.1177 | 0.1177 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.0564 | 0.1264 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0031 | 0.0244 | 0.0244 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0189 | 0.2611 | 0.9465 |
Brugia malayi | Importin beta-1 subunit | 0.0029 | 0.0221 | 0.0801 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.012 | 0.1576 | 0.353 |
Trichomonas vaginalis | CMGC family protein kinase | 0.005 | 0.0532 | 0.5984 |
Schistosoma mansoni | ran | 0.0022 | 0.0105 | 0.0105 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0031 | 0.0244 | 0.0244 |
Trypanosoma cruzi | DNA polymerase beta thumb, putative | 0.0042 | 0.0413 | 0.074 |
Loa Loa (eye worm) | nuclear hormone receptor-like 1 | 0.0016 | 0.0026 | 0.0058 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0189 | 0.2611 | 0.5847 |
Mycobacterium ulcerans | hypothetical protein | 0.0023 | 0.0131 | 0.0419 |
Trichomonas vaginalis | importin beta-1, putative | 0.0024 | 0.0138 | 0.0461 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0031 | 0.0244 | 0.0884 |
Echinococcus multilocularis | importin subunit beta 1 | 0.0029 | 0.0221 | 0.0221 |
Echinococcus granulosus | mitogen activated protein kinase | 0.005 | 0.0532 | 0.0532 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0093 | 0.1177 | 0.1177 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.0051 | 0.0551 | 0.1071 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0244 | 0.0546 |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.0026 | 0.0058 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0031 | 0.0244 | 0.0244 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0023 | 0.0131 | 0.0221 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0031 | 0.0244 | 0.0884 |
Schistosoma mansoni | thyroid hormone receptor | 0.0031 | 0.0244 | 0.0244 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0031 | 0.0244 | 0.0244 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0031 | 0.0244 | 0.0884 |
Schistosoma mansoni | thyroid hormone receptor | 0.0031 | 0.0244 | 0.0244 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0043 | 0.0096 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0031 | 0.0244 | 0.0244 |
Onchocerca volvulus | 0.0028 | 0.0194 | 0.4779 | |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0031 | 0.0244 | 0.0244 |
Loa Loa (eye worm) | abnormal chemotaxis protein 14 | 0.0043 | 0.0421 | 0.0942 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0023 | 0.0131 | 0.0062 |
Echinococcus multilocularis | protein patched | 0.0043 | 0.0421 | 0.0421 |
Mycobacterium ulcerans | long-chain-fatty-acid-CoA ligase | 0.0023 | 0.0131 | 0.0419 |
Schistosoma mansoni | tar DNA-binding protein | 0.0189 | 0.2611 | 0.2611 |
Toxoplasma gondii | CMGC kinase, MAPK family (ERK) MAPK-1 | 0.005 | 0.0532 | 1 |
Trichomonas vaginalis | chromobox protein, putative | 0.0069 | 0.0818 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0036 | 0.0317 | 0.1819 |
Entamoeba histolytica | hypothetical protein | 0.0024 | 0.0138 | 0.0282 |
Schistosoma mansoni | hypothetical protein | 0.0041 | 0.0398 | 0.0398 |
Plasmodium falciparum | GTP-binding nuclear protein RAN/TC4 | 0.0022 | 0.0105 | 0.35 |
Echinococcus multilocularis | chromobox protein 1 | 0.0069 | 0.0818 | 0.0818 |
Trypanosoma brucei | importin beta-1 subunit, putative | 0.0029 | 0.0221 | 0.0278 |
Onchocerca volvulus | 0.0023 | 0.0131 | 0.3217 | |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.0026 | 0.0058 |
Brugia malayi | RNA, U transporter 1 | 0.0083 | 0.103 | 0.3733 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0031 | 0.0244 | 0.0244 |
Onchocerca volvulus | 0.0028 | 0.0194 | 0.4779 | |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0031 | 0.0244 | 0.0546 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0031 | 0.0244 | 0.0884 |
Schistosoma mansoni | hypothetical protein | 0.0313 | 0.4466 | 0.4466 |
Echinococcus granulosus | snurportin 1 | 0.0313 | 0.4466 | 0.4466 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.0237 | 0.0531 |
Mycobacterium tuberculosis | Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) | 0.0023 | 0.0131 | 0.0483 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0023 | 0.0131 | 0.0062 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0056 | 0.0626 | 0.2772 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0031 | 0.0244 | 0.0244 |
Giardia lamblia | Kinase, CMGC MAPK | 0.005 | 0.0532 | 1 |
Schistosoma mansoni | patched 1 | 0.0043 | 0.0421 | 0.0421 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0221 | 0.0495 |
Trichomonas vaginalis | Importin beta-1 subunit, putative | 0.0024 | 0.0138 | 0.0461 |
Echinococcus multilocularis | Niemann Pick C1 protein | 0.0099 | 0.127 | 0.127 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0031 | 0.0244 | 0.0884 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0031 | 0.0244 | 0.0546 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0056 | 0.0626 | 0.2772 |
Brugia malayi | hypothetical protein | 0.0036 | 0.0317 | 0.1149 |
Trichomonas vaginalis | chromobox protein, putative | 0.0042 | 0.0407 | 0.4233 |
Trypanosoma brucei | importin beta-1 subunit, putative | 0.0029 | 0.0221 | 0.0278 |
Brugia malayi | nuclear hormone receptor | 0.0031 | 0.0244 | 0.0884 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0031 | 0.0244 | 0.0884 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0031 | 0.0244 | 0.0884 |
Plasmodium falciparum | importin beta, putative | 0.0029 | 0.0221 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0189 | 0.2611 | 0.2611 |
Echinococcus granulosus | GPCR family 2 | 0.0063 | 0.0724 | 0.0724 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0093 | 0.1177 | 0.1177 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0031 | 0.0244 | 0.0546 |
Schistosoma mansoni | tar DNA-binding protein | 0.0189 | 0.2611 | 0.2611 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0031 | 0.0244 | 0.0884 |
Echinococcus multilocularis | chromobox protein 1 | 0.0069 | 0.0818 | 0.0818 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0036 | 0.0317 | 0.0317 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0093 | 0.1177 | 0.2636 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0158 | 0.2147 | 1 |
Echinococcus granulosus | intermediate filament protein | 0.0028 | 0.0194 | 0.0194 |
Schistosoma mansoni | hypothetical protein | 0.0036 | 0.0317 | 0.0317 |
Schistosoma mansoni | nuclear hormone receptor | 0.0031 | 0.0244 | 0.0244 |
Trypanosoma cruzi | mitogen activated protein kinase 2, putative | 0.005 | 0.0532 | 0.1024 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.0421 | 0.0942 |
Trypanosoma cruzi | importin beta-1 subunit, putative | 0.0024 | 0.0138 | 0.0079 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0093 | 0.1177 | 0.1177 |
Echinococcus granulosus | Niemann Pick C1 protein | 0.0142 | 0.1908 | 0.1908 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0023 | 0.0131 | 0.0221 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0131 | 0.0293 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0031 | 0.0244 | 0.0884 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0093 | 0.1177 | 0.1177 |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.0026 | 0.0058 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0023 | 0.0131 | 0.0483 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.