Detailed information for compound 71628

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 583.78 | Formula: C29H49N3O7S
  • H donors: 4 H acceptors: 6 LogP: 4.21 Rotable bonds: 20
    Rule of 5 violations (Lipinski): 2
  • SMILES: CC(C[C@@H]([C@H](CCS(=O)(=O)CC(C)C)O)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)OC(C)(C)C)C)C
  • InChi: 1S/C29H49N3O7S/c1-19(2)16-23(25(33)14-15-40(37,38)18-20(3)4)31-26(34)21(5)30-27(35)24(17-22-12-10-9-11-13-22)32-28(36)39-29(6,7)8/h9-13,19-21,23-25,33H,14-18H2,1-8H3,(H,30,35)(H,31,34)(H,32,36)/t21-,23-,24-,25-/m0/s1
  • InChiKey: OHSLOABMMVYBJJ-LFBFJMOVSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens renin Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Babesia bovis eukaryotic aspartyl protease family protein Get druggable targets OG5_126885 All targets in OG5_126885
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126885 All targets in OG5_126885
Candida albicans vacuolar aspartic proteinase precursor similar to S. cerevisiae PEP4 (YPL154C) Get druggable targets OG5_126885 All targets in OG5_126885
Plasmodium knowlesi plasmepsin IV, putative Get druggable targets OG5_126885 All targets in OG5_126885
Plasmodium yoelii hypothetical protein Get druggable targets OG5_126885 All targets in OG5_126885
Plasmodium falciparum plasmepsin VI Get druggable targets OG5_126885 All targets in OG5_126885
Plasmodium berghei plasmepsin VI Get druggable targets OG5_126885 All targets in OG5_126885
Schistosoma mansoni cathepsin D (A01 family) Get druggable targets OG5_126885 All targets in OG5_126885
Theileria parva cathepsin E, putative Get druggable targets OG5_126885 All targets in OG5_126885
Cryptosporidium parvum membrane bound aspartyl proteinase with a signal peptide plus transmembrane domain Get druggable targets OG5_126885 All targets in OG5_126885
Plasmodium knowlesi aspartyl protease, putative Get druggable targets OG5_126885 All targets in OG5_126885
Toxoplasma gondii aspartyl protease ASP1 Get druggable targets OG5_126885 All targets in OG5_126885
Plasmodium berghei plasmepsin IV Get druggable targets OG5_126885 All targets in OG5_126885
Plasmodium yoelii plasmepsin Get druggable targets OG5_126885 All targets in OG5_126885
Plasmodium vivax aspartyl proteinase, putative Get druggable targets OG5_126885 All targets in OG5_126885
Schistosoma japonicum Cathepsin D precursor, putative Get druggable targets OG5_126885 All targets in OG5_126885
Plasmodium falciparum plasmepsin IV Get druggable targets OG5_126885 All targets in OG5_126885
Toxoplasma gondii aspartyl proteinase (eimepsin), putative Get druggable targets OG5_126885 All targets in OG5_126885
Theileria parva pepsinogen, putative Get druggable targets OG5_126885 All targets in OG5_126885
Loa Loa (eye worm) aspartic protease BmAsp-2 Get druggable targets OG5_126885 All targets in OG5_126885
Plasmodium falciparum plasmepsin II Get druggable targets OG5_126885 All targets in OG5_126885
Plasmodium falciparum plasmepsin I Get druggable targets OG5_126885 All targets in OG5_126885
Candida albicans vacuolar aspartic proteinase precursor similar to S. cerevisiae PEP4 (YPL154C) Get druggable targets OG5_126885 All targets in OG5_126885
Trichomonas vaginalis Clan AA, family A1, cathepsin D-like aspartic peptidase Get druggable targets OG5_126885 All targets in OG5_126885
Echinococcus granulosus cathepsin d lysosomal aspartyl protease Get druggable targets OG5_126885 All targets in OG5_126885
Neospora caninum Renin, related Get druggable targets OG5_126885 All targets in OG5_126885
Cryptosporidium hominis aspartyl protease precursor Get druggable targets OG5_126885 All targets in OG5_126885
Schistosoma japonicum ko:K01379 cathepsin D [EC3.4.23.5], putative Get druggable targets OG5_126885 All targets in OG5_126885
Plasmodium yoelii hypothetical protein Get druggable targets OG5_126885 All targets in OG5_126885
Schistosoma mansoni cathepsin D (A01 family) Get druggable targets OG5_126885 All targets in OG5_126885
Neospora caninum Pepsinogen A1, related Get druggable targets OG5_126885 All targets in OG5_126885
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) Get druggable targets OG5_126885 All targets in OG5_126885
Plasmodium vivax plasmepsin IV, putative Get druggable targets OG5_126885 All targets in OG5_126885
Echinococcus multilocularis cathepsin d (lysosomal aspartyl protease) Get druggable targets OG5_126885 All targets in OG5_126885
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Plasmodium falciparum plasmepsin X renin 406 aa 352 aa 26.4 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Onchocerca volvulus Neuropeptide F receptor homolog 0.0029 0.0024 0.0024
Trypanosoma brucei phosphatidylinositol kinase related protein, putative 0.0011 0.0005 0.0004
Schistosoma mansoni axis inhibition protein axin 0.0019 0.0013 0.0013
Toxoplasma gondii aspartyl protease 0.0014 0.0008 0.0008
Brugia malayi hypothetical protein 0.0029 0.0024 0.0025
Schistosoma mansoni cpg binding protein 0.0033 0.0028 0.0029
Plasmodium vivax glutathione reductase, putative 0.0046 0.0041 0.004
Plasmodium falciparum bifunctional dihydrofolate reductase-thymidylate synthase 0.9548 1 1
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0029 0.0024 0.0025
Trypanosoma cruzi DNA polymerase eta, putative 0.0034 0.0029 0.0029
Schistosoma mansoni amine GPCR 0.0029 0.0024 0.0025
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0074 0.0071 0.0074
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.002 0.0014 0.0014
Trypanosoma brucei importin beta-1 subunit, putative 0.0031 0.0025 0.0025
Echinococcus granulosus histone lysine methyltransferase setb 0.003 0.0024 0.0025
Giardia lamblia GTOR 0.002 0.0014 0.025
Loa Loa (eye worm) MH1 domain-containing protein 0.0017 0.0011 0.0011
Brugia malayi larval opioid receptor 0.0029 0.0024 0.0025
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0016 0.001 0.0009
Brugia malayi cytoplasmic intermediate filament protein 0.0014 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.0031 0.0025 0.0026
Trichomonas vaginalis conserved hypothetical protein 0.0007 0 0.0001
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0023 0.0017 0.0017
Brugia malayi 6-phosphofructokinase 0.0105 0.0103 0.0107
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0023 0.0017 0.0017
Trichomonas vaginalis phosphofructokinase, putative 0.0105 0.0103 0.0226
Chlamydia trachomatis thymidylate kinase 0.0388 0.04 0.5371
Schistosoma mansoni amine GPCR 0.0029 0.0024 0.0025
Loa Loa (eye worm) hypothetical protein 0.0007 0.0001 0.0001
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0021 0.0015 0.0015
Brugia malayi RNA, U transporter 1 0.0087 0.0085 0.0088
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0029 0.0024 0.0025
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0012 0.0006 0.0006
Onchocerca volvulus 0.0014 0.0008 0.0007
Echinococcus granulosus RNA directed DNA polymerase reverse transcriptase 0.001 0.0004 0.0004
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0011 0.0004 0.0004
Echinococcus multilocularis microtubule associated protein 2 0.0672 0.0697 0.0725
Loa Loa (eye worm) hypothetical protein 0.0029 0.0024 0.0025
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0015 0.0014
Echinococcus multilocularis neuropeptides capa receptor 0.0029 0.0024 0.0025
Schistosoma mansoni DNA polymerase alpha catalytic subunit 0.0054 0.005 0.0051
Echinococcus granulosus dihydrofolate reductase 0.0717 0.0744 0.0775
Loa Loa (eye worm) G-protein coupled receptor 0.0029 0.0024 0.0025
Loa Loa (eye worm) hypothetical protein 0.0029 0.0024 0.0025
Schistosoma mansoni ferritin 0.0008 0.0002 0.0002
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0007 0 0.0001
Loa Loa (eye worm) aspartic protease BmAsp-2 0.0059 0.0055 0.0057
Loa Loa (eye worm) neuropeptide F receptor 0.0029 0.0024 0.0025
Trypanosoma brucei unspecified product 0.0055 0.0051 0.005
Loa Loa (eye worm) hypothetical protein 0.0029 0.0024 0.0025
Giardia lamblia ABC transporter, putative 0.0031 0.0025 0.0463
Brugia malayi Calcitonin receptor-like protein seb-1 0.0054 0.0049 0.0051
Brugia malayi Zinc knuckle family protein 0.001 0.0004 0.0004
Brugia malayi mothers against decapentaplegic homolog 3 0.0007 0.0001 0.0001
Brugia malayi hypothetical protein 0.0014 0.0008 0.0008
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0017 0.0011 0.0011
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0104 0.0102 0.0106
Echinococcus multilocularis bloom syndrome protein 0.0021 0.0015 0.0015
Plasmodium vivax thymidylate kinase, putative 0.0388 0.04 0.04
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0028 0.0023 0.03
Echinococcus granulosus 7TM GPCR rhodopsin 0.0029 0.0024 0.0025
Schistosoma mansoni phosphoglucomutase 0.0045 0.004 0.0041
Plasmodium falciparum plasmepsin VI 0.0059 0.0055 0.0055
Echinococcus granulosus orexin receptor type 2 0.0029 0.0024 0.0025
Trypanosoma cruzi UMP-CMP kinase, mitochondrial, putative 0.0152 0.0153 0.0153
Plasmodium vivax DNA polymerase delta catalytic subunit, putative 0.0015 0.0009 0.0008
Plasmodium falciparum glutathione reductase 0.0046 0.0041 0.0041
Loa Loa (eye worm) thymidylate kinase 0.0388 0.04 0.0417
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0019 0.0013 0.0013
Brugia malayi thymidylate synthase 0.9172 0.9606 1
Trypanosoma cruzi deoxyuridine triphosphatase, putative 0.04 0.0412 0.0412
Onchocerca volvulus 0.9172 0.9606 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0014 0.003
Schistosoma mansoni DNA polymerase eta 0.0048 0.0044 0.0045
Echinococcus multilocularis thymidylate kinase 0.0388 0.04 0.0416
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0014 0.003
Plasmodium falciparum plasmepsin II 0.0059 0.0055 0.0055
Mycobacterium ulcerans thymidylate synthase 0.9172 0.9606 1
Loa Loa (eye worm) hypothetical protein 0.0019 0.0013 0.0013
Echinococcus granulosus neuropeptide Y receptor 0.0029 0.0024 0.0025
Echinococcus granulosus DNA polymerase zeta catalytic subunit 0.0015 0.0009 0.0009
Schistosoma mansoni hypothetical protein 0.0017 0.0011 0.0011
Plasmodium falciparum plasmepsin IV 0.0059 0.0055 0.0055
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0009 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0029 0.0024 0.0025
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0007 0 0.0001
Echinococcus granulosus tar DNA binding protein 0.0068 0.0064 0.0067
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0014 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.0009 0.0002 0.0002
Entamoeba histolytica hypothetical protein 0.0025 0.0019 0.0356
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0016 0.001 0.001
Brugia malayi G-protein coupled receptor 0.0029 0.0024 0.0025
Loa Loa (eye worm) hypothetical protein 0.0029 0.0024 0.0025
Entamoeba histolytica ATP-binding cassette protein, putative 0.0031 0.0025 0.0467
Trypanosoma cruzi DNA polymerase kappa, putative 0.0021 0.0015 0.0015
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0029 0.0024 0.0025
Mycobacterium tuberculosis Thymidylate kinase Tmk (dTMP kinase) (thymidylic acid kinase) (TMPK) 0.0388 0.04 0.0416
Entamoeba histolytica P-glyco protein 6, putative 0.0007 0 0.0009
Brugia malayi Pao retrotransposon peptidase family protein 0.001 0.0004 0.0004
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0007 0 0.0001
Echinococcus multilocularis serotonin receptor 0.0029 0.0024 0.0025
Leishmania major ATP-binding cassette protein subfamily C, member 5, putative 0.0031 0.0025 0.0025
Toxoplasma gondii phosphofructokinase PFKII 0.0028 0.0023 0.0023
Schistosoma mansoni hypothetical protein 0.0009 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0009 0.0003 0.0003
Brugia malayi G-protein coupled receptor 0.0029 0.0024 0.0025
Loa Loa (eye worm) hypothetical protein 0.0014 0.0008 0.0008
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0011 0.0004 0.0004
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0029 0.0024 0.0025
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0029 0.0024 0.0025
Trichomonas vaginalis importin beta-1, putative 0.0025 0.0019 0.0042
Echinococcus granulosus regulator of G protein signaling 7 0.0019 0.0013 0.0013
Brugia malayi RNase H family protein 0.0045 0.004 0.0041
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0024 0.0025
Loa Loa (eye worm) transcription factor SMAD2 0.0245 0.0249 0.026
Toxoplasma gondii O-linked N-acetylglucosamine transferase 0.0039 0.0034 0.0034
Leishmania major importin beta-1 subunit, putative 0.0025 0.0019 0.0019
Echinococcus granulosus neuropeptide s receptor 0.0029 0.0024 0.0025
Trypanosoma cruzi multidrug resistance protein E, putative 0.0031 0.0025 0.0025
Schistosoma mansoni hypothetical protein 0.0388 0.04 0.0416
Trichomonas vaginalis thymidine kinase, putative 0.0519 0.0537 0.1177
Loa Loa (eye worm) PXA domain-containing protein 0.0019 0.0013 0.0013
Echinococcus multilocularis snurportin 1 0.0328 0.0337 0.035
Brugia malayi A-kinase anchor protein 10, precursor 0.0019 0.0013 0.0013
Leishmania major p-glycoprotein e 0.0031 0.0025 0.0025
Loa Loa (eye worm) latrophilin receptor protein 2 0.0017 0.0011 0.0011
Trypanosoma cruzi DNA polymerase epsilon catalytic subunit, putative 0.0015 0.0009 0.0009
Onchocerca volvulus Telomerase reverse transcriptase homolog 0.001 0.0004 0.0003
Echinococcus multilocularis DNA polymerase alpha catalytic subunit 0.0054 0.005 0.0051
Echinococcus multilocularis g-protein coupled receptor 0.0029 0.0024 0.0025
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0029 0.0024 0.0025
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0029 0.0024 0.0025
Trichomonas vaginalis phosphofructokinase, putative 0.0028 0.0023 0.005
Echinococcus multilocularis regulator of G protein signaling 0.0019 0.0013 0.0013
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0007 0 0.0001
Trypanosoma cruzi ribonuclease H1, putative 0.0045 0.004 0.004
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0016 0.001 0.001
Onchocerca volvulus 0.0029 0.0024 0.0024
Loa Loa (eye worm) multidrug resistance-associated protein 0.0024 0.0018 0.0019
Echinococcus multilocularis mothers against decapentaplegic 5 0.0017 0.0011 0.0011
Echinococcus granulosus mixed lineage leukemia protein mll 0.0009 0.0002 0.0002
Echinococcus granulosus mothers against decapentaplegic 6 0.0007 0.0001 0.0001
Entamoeba histolytica phosphofructokinase, putative 0.0105 0.0103 0.1919
Brugia malayi Pao retrotransposon peptidase family protein 0.001 0.0004 0.0004
Plasmodium falciparum plasmepsin VII 0.0014 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.0029 0.0024 0.0025
Schistosoma mansoni memapsin-2 (A01 family) 0.0014 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.0009 0.0002 0.0002
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0021 0.0015 0.0015
Brugia malayi neuropeptide F receptor 0.0029 0.0024 0.0025
Trypanosoma brucei unspecified product 0.0021 0.0015 0.0014
Schistosoma mansoni multidrug resistance protein 0.0031 0.0025 0.0026
Trypanosoma brucei DNA polymerase kappa, putative 0.0014 0.0008 0.0008
Trichomonas vaginalis DNA polymerase alpha catalytic subunit, putative 0.0008 0.0002 0.0004
Loa Loa (eye worm) hypothetical protein 0.0029 0.0024 0.0025
Mycobacterium leprae PROBABLE THYMIDYLATE SYNTHASE THYX (TS) (TSase) 0.5019 0.5254 0.5469
Brugia malayi Zinc knuckle family protein 0.001 0.0004 0.0004
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0074 0.0071 0.0074
Trichomonas vaginalis DNA polymerase alpha catalytic subunit, putative 0.0024 0.0018 0.0039
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0023 0.0017 0.0017
Schistosoma mansoni neuropeptide f receptor 76f 0.0029 0.0024 0.0025
Trichomonas vaginalis abcb9, putative 0.0007 0 0.0001
Trypanosoma brucei deoxyuridine triphosphatase, putative 0.04 0.0412 0.0411
Entamoeba histolytica ATP-binding cassette protein, putative 0.0031 0.0025 0.0467
Loa Loa (eye worm) thioredoxin reductase 0.0046 0.0041 0.0043
Entamoeba histolytica P-glycoprotein-5 0.0007 0 0.0009
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0031 0.0025 0.0025
Trypanosoma cruzi DNA polymerase I alpha catalytic subunit, putative 0.0024 0.0018 0.0018
Loa Loa (eye worm) hypothetical protein 0.0007 0.0001 0.0001
Trichomonas vaginalis PIKK family atypical protein kinase 0.0011 0.0005 0.001
Leishmania major DNA polymerase I alpha catalytic subunit, putative 0.0024 0.0018 0.0018
Loa Loa (eye worm) hypothetical protein 0.0029 0.0024 0.0025
Brugia malayi Pao retrotransposon peptidase family protein 0.001 0.0004 0.0004
Trichomonas vaginalis ferritin, putative 0.0008 0.0002 0.0004
Brugia malayi hypothetical protein 0.0029 0.0024 0.0025
Plasmodium vivax aspartyl protease, putative 0.0014 0.0008 0.0007
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0019 0.0013 0.0013
Echinococcus multilocularis neuropeptide receptor A26 0.0029 0.0024 0.0025
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.001 0.001
Trichomonas vaginalis phosphofructokinase, putative 0.0105 0.0103 0.0226
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0007 0 0.0001
Echinococcus granulosus KRAB A domain containing protein 0.001 0.0004 0.0004
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0019 0.0013 0.0013
Loa Loa (eye worm) hypothetical protein 0.0029 0.0024 0.0025
Brugia malayi Pao retrotransposon peptidase family protein 0.001 0.0004 0.0004
Brugia malayi DNA polymerase alpha catalytic subunit 0.0044 0.0039 0.004
Entamoeba histolytica thymidine kinase, putative 0.0519 0.0537 1
Echinococcus granulosus TGF beta signal transducer SmadC 0.0017 0.0011 0.0011
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0015 0.0014
Onchocerca volvulus 0.0029 0.0024 0.0024
Trypanosoma brucei ribonuclease H1 0.0045 0.004 0.0039
Plasmodium falciparum plasmepsin IX 0.0014 0.0008 0.0008
Echinococcus multilocularis rhodopsin orphan GPCR 0.0029 0.0024 0.0025
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0014 0.003
Onchocerca volvulus DNA polymerase delta catalytic subunit homolog 0.0015 0.0009 0.0008
Loa Loa (eye worm) hypothetical protein 0.0031 0.0025 0.0026
Brugia malayi hypothetical protein 0.0029 0.0024 0.0025
Brugia malayi Pao retrotransposon peptidase family protein 0.001 0.0004 0.0004
Trichomonas vaginalis thymidylate kinase, putative 0.0388 0.04 0.0876
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0029 0.0024 0.0025
Brugia malayi hypothetical protein 0.001 0.0004 0.0004
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0067 0.0064 0.0066
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0015 0.0014
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0017 0.0011 0.0011
Loa Loa (eye worm) hypothetical protein 0.0029 0.0024 0.0025
Echinococcus granulosus fmrfamide receptor 0.0029 0.0024 0.0025
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0105 0.0103 0.0103
Brugia malayi Pao retrotransposon peptidase family protein 0.001 0.0004 0.0004
Trichomonas vaginalis glutathione reductase, putative 0.0016 0.001 0.0021
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0023 0.0017 0.0016
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0014 0.003
Trichomonas vaginalis Clan AA, family A1, cathepsin D-like aspartic peptidase 0.0059 0.0055 0.012
Loa Loa (eye worm) cytochrome P450 family protein 0.0012 0.0006 0.0006
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0029 0.0024 0.0025
Trichomonas vaginalis thymidine kinase, putative 0.0519 0.0537 0.1177
Echinococcus granulosus rhodopsin orphan GPCR 0.0029 0.0024 0.0025
Brugia malayi TAR-binding protein 0.0068 0.0064 0.0067
Trypanosoma cruzi cytochrome P450, putative 0.0012 0.0006 0.0006
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0014 0.003
Giardia lamblia DNA polymerase delta, catalytic subunit 0.0015 0.0009 0.0157
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0007 0 0.0001
Echinococcus granulosus allatostatin A receptor 0.0029 0.0024 0.0025
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0016 0.001 0.0009
Trypanosoma cruzi dihydrofolate reductase-thymidylate synthase, putative 0.4363 0.4566 0.4566
Giardia lamblia DNA polymerase alpha subunit A 0.0046 0.0041 0.0756
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0009 0.0002 0.0002
Brugia malayi Pao retrotransposon peptidase family protein 0.001 0.0004 0.0004
Echinococcus multilocularis neuropeptide FF receptor 2 0.0029 0.0024 0.0025
Trypanosoma cruzi multidrug resistance-associated protein, putative 0.0031 0.0025 0.0025
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.002 0.0014 0.0013
Loa Loa (eye worm) MH2 domain-containing protein 0.0017 0.0011 0.0011
Trypanosoma cruzi hypothetical protein 0.0023 0.0018 0.0018
Giardia lamblia O-linked GlcNAc transferase 0.0023 0.0017 0.0315
Trypanosoma brucei multidrug resistance-associated protein, putative 0.0031 0.0025 0.0025
Schistosoma mansoni opsin-like receptor 0.0029 0.0024 0.0025
Brugia malayi hypothetical protein 0.0029 0.0024 0.0025
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0014 0.003
Brugia malayi Pre-SET motif family protein 0.003 0.0024 0.0025
Giardia lamblia O-linked GlcNAc transferase 0.0039 0.0034 0.0633
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0018 0.0012 0.0012
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0016 0.001 0.001
Trypanosoma brucei hypothetical protein, conserved 0.0055 0.0051 0.005
Echinococcus multilocularis 6 phosphofructokinase 0.0105 0.0103 0.0107
Schistosoma mansoni DNA helicase recq5 0.0009 0.0002 0.0002
Echinococcus granulosus neuropeptide receptor 0.0029 0.0024 0.0025
Entamoeba histolytica ABC transporter, putative 0.0031 0.0025 0.0467
Echinococcus multilocularis fmrfamide receptor 0.0029 0.0024 0.0025
Onchocerca volvulus Putative thymidylate kinase 0.0388 0.04 0.0416
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0029 0.0024 0.0025
Echinococcus granulosus multidrug resistance associated protein 1 0.0031 0.0025 0.0026
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0014 0.003
Brugia malayi MH2 domain containing protein 0.0245 0.0249 0.0259
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0016 0.001 0.0123
Plasmodium vivax 6-phosphofructokinase, putative 0.0028 0.0023 0.0022
Schistosoma mansoni phosphoglucomutase 0.0045 0.004 0.0041
Treponema pallidum hypothetical protein 0.0016 0.0009 0.0192
Plasmodium vivax DNA polymerase epsilon, catalytic subunit a, putative 0.0015 0.0009 0.0008
Echinococcus multilocularis lamin dm0 0.0026 0.0021 0.0021
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0105 0.0103 0.0107
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0029 0.0024 0.0024
Wolbachia endosymbiont of Brugia malayi ribonuclease HI 0.0045 0.004 0.0986
Echinococcus granulosus dna polymerase eta 0.0048 0.0044 0.0045
Entamoeba histolytica ATP-binding cassette protein, putative 0.0031 0.0025 0.0467
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0015 0.0014
Giardia lamblia Multidrug resistance-associated protein 1 0.0031 0.0025 0.0463
Giardia lamblia Reverse transcriptase/endonuclease, putative 0.001 0.0004 0.0065
Plasmodium vivax thioredoxin reductase, putative 0.0046 0.0041 0.004
Entamoeba histolytica Ran family GTPase 0.0023 0.0017 0.0312
Echinococcus multilocularis rhodopsin orphan GPCR 0.0029 0.0024 0.0025
Loa Loa (eye worm) thymidylate synthase 0.9172 0.9606 1
Echinococcus granulosus neuropeptides capa receptor 0.0029 0.0024 0.0025
Schistosoma mansoni z-protein (S1r protein) 0.0019 0.0013 0.0013
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0019 0.0013 0.0013
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0013 0.0028
Plasmodium falciparum DNA polymerase delta catalytic subunit 0.0015 0.0009 0.0009
Schistosoma mansoni hypothetical protein 0.0017 0.0011 0.0011
Onchocerca volvulus 0.0029 0.0024 0.0024
Echinococcus granulosus 7tm_1 domain containing protein 0.0029 0.0024 0.0025
Loa Loa (eye worm) phosphatidylinositol 3 0.0031 0.0026 0.0027
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0014 0.0008 0.0008
Trichomonas vaginalis thymidylate kinase, putative 0.0388 0.04 0.0876
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0019 0.0013 0.0013
Brugia malayi Thioredoxin reductase 0.0046 0.0041 0.0042
Schistosoma mansoni Smad4 0.0007 0.0001 0.0001
Trypanosoma brucei DNA polymerase IV, putative 0.0021 0.0015 0.0014
Trichomonas vaginalis phosphofructokinase, putative 0.0105 0.0103 0.0226
Trypanosoma brucei unspecified product 0.0014 0.0008 0.0008
Echinococcus multilocularis dro:myosuppressin receptor 0.0029 0.0024 0.0025
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.003 0.0024 0.0024
Toxoplasma gondii DNA polymerase (pol2) superfamily protein 0.0044 0.0039 0.0039
Echinococcus multilocularis RNA directed DNA polymerase (reverse transcriptase) 0.001 0.0004 0.0004
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0029 0.0024 0.0025
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0014 0.003
Brugia malayi Melatonin receptor type 1A 0.0029 0.0024 0.0025
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0029 0.0024 0.0025
Leishmania major cytochrome p450-like protein 0.0012 0.0006 0.0006
Brugia malayi Regulator of G protein signaling domain containing protein 0.0019 0.0013 0.0013
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0029 0.0024 0.0025
Giardia lamblia Reverse transcriptase/endonuclease, putative 0.001 0.0004 0.0065
Echinococcus granulosus expressed protein 0.0363 0.0374 0.0389
Onchocerca volvulus DNA polymerase epsilon catalytic subunit A homolog 0.0015 0.0009 0.0008
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0029 0.0024 0.0025
Entamoeba histolytica P-glycoprotein 5, putative 0.0007 0 0.0004
Onchocerca volvulus 0.0029 0.0024 0.0024
Schistosoma mansoni hypothetical protein 0.0017 0.0011 0.0011
Trypanosoma brucei dihydrofolate reductase-thymidylate synthase 0.9548 1 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0014 0.003
Echinococcus granulosus tm gpcr rhodopsin 0.0029 0.0024 0.0025
Echinococcus multilocularis neuropeptides capa receptor 0.0029 0.0024 0.0025
Mycobacterium leprae PROBABLE BACTERIOFERRITIN BFRA 0.0008 0.0002 0.0001
Brugia malayi intermediate filament protein 0.0026 0.0021 0.0021
Brugia malayi hypothetical protein 0.4363 0.4566 0.4753
Schistosoma mansoni serine/threonine protein kinase 0.001 0.0004 0.0004
Entamoeba histolytica hypothetical protein 0.0019 0.0013 0.0235
Loa Loa (eye worm) hypothetical protein 0.0029 0.0024 0.0025
Loa Loa (eye worm) hypothetical protein 0.0017 0.001 0.0011
Echinococcus granulosus G protein coupled receptor 139 0.0029 0.0024 0.0025
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0013 0.0028
Entamoeba histolytica hypothetical protein 0.0031 0.0025 0.0467
Schistosoma mansoni hypothetical protein 0.0029 0.0024 0.0025
Trichomonas vaginalis conserved hypothetical protein 0.4363 0.4566 1
Trypanosoma brucei DNA polymerase kappa, putative 0.0014 0.0008 0.0008
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0025 0.0019 0.0042
Trypanosoma cruzi DNA polymerase kappa, putative 0.0021 0.0015 0.0015
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.002 0.0014 0.0014
Echinococcus multilocularis RNA directed DNA polymerase (reverse transcriptase) 0.001 0.0004 0.0004
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0014 0.003
Onchocerca volvulus 0.0029 0.0024 0.0024
Mycobacterium tuberculosis Probable reductase 0.0104 0.0102 0.0106
Schistosoma mansoni thymidylate kinase 0.0388 0.04 0.0416
Mycobacterium tuberculosis Conserved hypothetical protein 0.0021 0.0015 0.0015
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0016 0.001 0.0009
Echinococcus multilocularis multidrug resistance associated protein 7 0.0031 0.0025 0.0026
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0029 0.0024 0.0025
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0014 0.003
Schistosoma mansoni smad1 5 8 and 0.0017 0.0011 0.0011
Echinococcus granulosus g protein coupled receptor 0.0029 0.0024 0.0025
Plasmodium falciparum DNA polymerase epsilon catalytic subunit A, putative 0.0008 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0029 0.0024 0.0025
Plasmodium falciparum plasmepsin III 0.0014 0.0008 0.0008
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0024 0.0025
Loa Loa (eye worm) G-protein coupled receptor 0.0029 0.0024 0.0025
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0029 0.0024 0.0025
Entamoeba histolytica Thymidylate kinase, putative 0.0388 0.04 0.7446
Trypanosoma brucei retrotransposon hot spot protein 4 (RHS4), interrupted 0.0055 0.0051 0.005
Loa Loa (eye worm) ABC transporter 0.0007 0 0.0001
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0104 0.0102 0.0106
Loa Loa (eye worm) hypothetical protein 0.0029 0.0024 0.0025
Echinococcus granulosus tm gpcr rhodopsin 0.0029 0.0024 0.0025
Echinococcus granulosus PIK kinase FAT and Armadillo domain containing protein 0.0009 0.0002 0.0002
Brugia malayi DNA polymerase family B containing protein 0.0015 0.0009 0.0009
Brugia malayi hypothetical protein 0.0019 0.0013 0.0013
Trichomonas vaginalis ABC transporter, putative 0.0007 0 0.0001
Loa Loa (eye worm) dihydrofolate reductase 0.0717 0.0744 0.0775
Plasmodium vivax DNA polymerase zeta catalytic subunit, putative 0.0015 0.0009 0.0008
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0012 0.0005 0.0005
Brugia malayi hypothetical protein 0.0029 0.0024 0.0025
Onchocerca volvulus 0.0029 0.0024 0.0024
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0015 0.0014
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0007 0 0.0001
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0104 0.0102 0.0106
Schistosoma mansoni multidrug resistance protein 0.0031 0.0025 0.0026
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0007 0 0.0001
Schistosoma mansoni multidrug resistance protein 0.0031 0.0025 0.0026
Echinococcus granulosus microtubule associated protein 2 0.0672 0.0697 0.0725
Mycobacterium ulcerans 6-phosphofructokinase 0.0105 0.0103 0.0107
Brugia malayi latrophilin 2 splice variant baaae 0.0037 0.0031 0.0033
Trichomonas vaginalis conserved hypothetical protein 0.0007 0 0.0001
Brugia malayi 6-phosphofructokinase 0.0105 0.0103 0.0107
Trypanosoma cruzi multidrug resistance-associated protein, putative 0.0031 0.0025 0.0025
Echinococcus multilocularis mothers against decapentaplegic 6 0.0007 0.0001 0.0001
Trichomonas vaginalis PIKK family atypical protein kinase 0.0011 0.0005 0.001
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0014 0.003
Trichomonas vaginalis DNA polymerase delta catalytic subunit, putative 0.0015 0.0009 0.0019
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0026 0.0021 0.0021
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0029 0.0024 0.0025
Echinococcus granulosus dro:myosuppressin receptor 0.0029 0.0024 0.0025
Brugia malayi reverse transcriptase 0.001 0.0004 0.0004
Trichomonas vaginalis ribonuclease H1, putative 0.0045 0.004 0.0087
Schistosoma mansoni hypothetical protein 0.001 0.0004 0.0004
Toxoplasma gondii aspartyl protease ASP3 0.0014 0.0008 0.0008
Brugia malayi PXA domain containing protein 0.0019 0.0013 0.0013
Loa Loa (eye worm) hypothetical protein 0.003 0.0024 0.0025
Trichomonas vaginalis phosphofructokinase, putative 0.0028 0.0023 0.005
Schistosoma mansoni neuropeptide receptor 0.0029 0.0024 0.0025
Trichomonas vaginalis PIKK family atypical protein kinase 0.0011 0.0005 0.001
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0046 0.0041 0.0042
Trichomonas vaginalis phosphofructokinase, putative 0.0028 0.0023 0.005
Schistosoma mansoni serine/threonine protein kinase 0.0019 0.0013 0.0013
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0029 0.0024 0.0025
Loa Loa (eye worm) hypothetical protein 0.0008 0.0002 0.0002
Onchocerca volvulus Ribonuclease H1 homolog 0.0045 0.004 0.0041
Trypanosoma brucei DNA polymerase delta catalytic subunit, putative 0.0015 0.0009 0.0008
Schistosoma mansoni amine GPCR 0.0029 0.0024 0.0025
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0014 0.003
Brugia malayi MH1 domain containing protein 0.0009 0.0003 0.0003
Brugia malayi regulator of G-protein signaling rgs-7 0.0019 0.0013 0.0013
Trypanosoma brucei importin beta-1 subunit, putative 0.0031 0.0025 0.0025
Loa Loa (eye worm) hypothetical protein 0.0029 0.0024 0.0025
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0116 0.0114 0.0119
Brugia malayi putative neuropeptide receptor 0.0029 0.0024 0.0025
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0007 0 0.0001
Trypanosoma brucei thymidine kinase 0.0519 0.0537 0.0537
Entamoeba histolytica P-glycoprotein-2 0.0007 0 0.0009
Schistosoma mansoni hypothetical protein 0.0029 0.0024 0.0025
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0007 0 0.0001
Echinococcus multilocularis cathepsin d (lysosomal aspartyl protease) 0.0059 0.0055 0.0057
Loa Loa (eye worm) hypothetical protein 0.0029 0.0024 0.0025
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0014 0.003
Toxoplasma gondii aspartyl protease ASP1 0.0059 0.0055 0.0055
Loa Loa (eye worm) hypothetical protein 0.0029 0.0024 0.0025
Schistosoma mansoni smad1 5 8 and 0.0017 0.0011 0.0011
Leishmania major ATP-binding cassette protein subfamily C, member 6, putative 0.0031 0.0025 0.0025
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0023 0.0017 0.0307
Trichomonas vaginalis mercuric reductase, putative 0.0016 0.001 0.0021
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0014 0.003
Echinococcus granulosus serine protein kinase ATM 0.0011 0.0005 0.0005
Mycobacterium tuberculosis Probable bacterioferritin BfrA 0.0008 0.0002 0.0001
Trichomonas vaginalis DNA polymerase II, putative 0.0024 0.0018 0.0039
Entamoeba histolytica ATP-binding cassette protein, putative 0.0031 0.0025 0.0467
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.002 0.0014 0.0254
Echinococcus multilocularis DNA polymerase zeta catalytic subunit 0.0015 0.0009 0.0009
Mycobacterium ulcerans DNA polymerase IV 0.0021 0.0015 0.0015
Loa Loa (eye worm) hypothetical protein 0.0029 0.0024 0.0025
Echinococcus multilocularis ferritin 0.0008 0.0002 0.0002
Mycobacterium ulcerans dihydrofolate reductase DfrA 0.0717 0.0744 0.0775
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0029 0.0024 0.0025
Onchocerca volvulus 0.0026 0.0021 0.0021
Loa Loa (eye worm) neuropeptide F receptor 0.0029 0.0024 0.0025
Trichomonas vaginalis phosphofructokinase, putative 0.0028 0.0023 0.005
Mycobacterium ulcerans DNA polymerase IV 0.0021 0.0015 0.0015
Giardia lamblia Reverse transcriptase/endonuclease 0.001 0.0004 0.0065
Echinococcus granulosus thymidylate synthase 0.9172 0.9606 1
Brugia malayi thymidylate kinase 0.0388 0.04 0.0416
Echinococcus granulosus rhodopsin orphan GPCR 0.0029 0.0024 0.0025
Echinococcus multilocularis RNA directed DNA polymerase (reverse transcriptase) 0.001 0.0004 0.0004
Plasmodium falciparum importin beta, putative 0.0031 0.0025 0.0025
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0014 0.003
Onchocerca volvulus 0.001 0.0004 0.0003
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.001 0.001
Schistosoma mansoni blooms syndrome DNA helicase 0.0016 0.001 0.001
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0028 0.0023 0.0023
Leishmania major phosphatidylinositol 3-kinase, putative 0.002 0.0014 0.0014
Trypanosoma cruzi deoxyuridine triphosphatase, putative 0.04 0.0412 0.0412
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0029 0.0024 0.0025
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0014 0.003
Brugia malayi hypothetical protein 0.0029 0.0024 0.0025
Echinococcus granulosus bloom syndrome protein 0.0021 0.0015 0.0015
Echinococcus multilocularis neuropeptide Y receptor 0.0029 0.0024 0.0025
Echinococcus multilocularis allatostatin A receptor 0.0029 0.0024 0.0025
Onchocerca volvulus 0.0029 0.0024 0.0024
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0059 0.0055 0.0057
Echinococcus multilocularis musashi 0.0026 0.0021 0.0021
Loa Loa (eye worm) RGS-3 protein 0.0019 0.0013 0.0013
Echinococcus granulosus dna polymerase kappa 0.0021 0.0015 0.0015
Trypanosoma brucei DNA polymerase IV, putative 0.0021 0.0015 0.0014
Schistosoma mansoni tar DNA-binding protein 0.0068 0.0064 0.0067
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.001 0.001
Loa Loa (eye worm) cytochrome P450 family protein 0.0012 0.0006 0.0006
Brugia malayi G protein-coupled receptor F59B2.13 0.0029 0.0024 0.0025
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0029 0.0024 0.0025
Mycobacterium tuberculosis Hypothetical protein 0.4363 0.4566 0.4753
Echinococcus multilocularis rhodopsin orphan GPCR 0.0029 0.0024 0.0025
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0029 0.0024 0.0025
Loa Loa (eye worm) hypothetical protein 0.0029 0.0024 0.0025
Loa Loa (eye worm) hypothetical protein 0.0029 0.0024 0.0025
Echinococcus granulosus Smad4 0.0017 0.0011 0.0011
Echinococcus multilocularis RNA directed DNA polymerase (reverse transcriptase) 0.001 0.0004 0.0004
Echinococcus multilocularis regulator of G protein signaling 7 0.0019 0.0013 0.0013
Loa Loa (eye worm) phosphofructokinase 0.0105 0.0103 0.0107
Leishmania major DNA polymerase delta catalytic subunit, putative 0.0015 0.0009 0.0009
Schistosoma mansoni 6-phosphofructokinase 0.0105 0.0103 0.0107
Echinococcus multilocularis mothers against decapentaplegic 2 0.0007 0.0001 0.0001
Echinococcus multilocularis dnaJ subfamily B 0.0445 0.0459 0.0478
Echinococcus multilocularis g protein coupled receptor 0.0029 0.0024 0.0025
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0017 0.0011 0.0011
Plasmodium vivax 6-phosphofructokinase, putative 0.0028 0.0023 0.0022
Toxoplasma gondii 6-phosphofructokinase 0.0028 0.0023 0.0023
Onchocerca volvulus 0.003 0.0024 0.0025
Schistosoma mansoni DNA polymerase alpha catalytic subunit 0.002 0.0014 0.0015
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.002 0.0014 0.0014
Entamoeba histolytica protein kinase rad3, putative 0.0011 0.0005 0.0087
Schistosoma mansoni lamin 0.0026 0.0021 0.0021
Toxoplasma gondii histone lysine methyltransferase SET1 0.006 0.0056 0.0056
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0074 0.0071 0.0071
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0007 0 0.0001
Echinococcus multilocularis lamin 0.0026 0.0021 0.0021
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.001 0.001
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0015 0.0014
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.003 0.0024 0.0025
Loa Loa (eye worm) UDP-N-acetylglucosamine-peptide N-acetylglucosaminyltransferase 0.004 0.0035 0.0036
Schistosoma mansoni hypothetical protein 0.0029 0.0024 0.0025
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0029 0.0024 0.0025
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0016 0.001 0.001
Loa Loa (eye worm) aspartic protease BmAsp-1 0.0014 0.0008 0.0008
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0029 0.0024 0.0025
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0116 0.0114 0.0119
Loa Loa (eye worm) hypothetical protein 0.0011 0.0005 0.0005
Toxoplasma gondii target of rapamycin (TOR), putative 0.002 0.0014 0.0014
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0024 0.0025
Loa Loa (eye worm) ABC transporter transmembrane region family protein 0.0031 0.0025 0.0026
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0014 0.003
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0014 0.003
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0007 0 0.0001
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.002 0.0014 0.0013
Echinococcus granulosus multidrug resistance associated protein 7 0.0031 0.0025 0.0026
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0028 0.0023 0.0023
Trichomonas vaginalis helicase, putative 0.0007 0 0.0001
Echinococcus multilocularis orexin receptor type 2 0.0029 0.0024 0.0025
Giardia lamblia Sgs1 DNA helicase, putative 0.0009 0.0002 0.0034
Trichomonas vaginalis NeSL-1_NeSL reverse transcriptases, putative 0.001 0.0004 0.0008
Trichomonas vaginalis ABC transporter, putative 0.0007 0 0.0001
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0104 0.0102 0.0106
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0016 0.001 0.001
Wolbachia endosymbiont of Brugia malayi thymidylate kinase 0.0388 0.04 1
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0014 0.0008 0.0008
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0016 0.001 0.0009
Schistosoma mansoni ferritin light chain 0.0008 0.0002 0.0002
Plasmodium falciparum plasmepsin I 0.0059 0.0055 0.0055
Trypanosoma cruzi trypanothione reductase, putative 0.0046 0.0041 0.0041
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0029 0.0024 0.0025
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0017 0.0011 0.0011
Schistosoma mansoni lamin 0.0026 0.0021 0.0021
Echinococcus multilocularis RNA directed DNA polymerase (reverse transcriptase) 0.001 0.0004 0.0004
Schistosoma mansoni microtubule-associated protein tau 0.0672 0.0697 0.0725
Echinococcus multilocularis dna polymerase eta 0.0048 0.0044 0.0045
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0023 0.0017 0.0016
Echinococcus granulosus DNA polymerase delta catalytic subunit 0.0015 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.0048 0.0044 0.0045
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0007 0 0.0001
Echinococcus granulosus cathepsin d lysosomal aspartyl protease 0.0059 0.0055 0.0057
Loa Loa (eye worm) hypothetical protein 0.0029 0.0024 0.0025
Brugia malayi Importin beta-1 subunit 0.0031 0.0025 0.0026
Brugia malayi Serotonin receptor 0.0029 0.0024 0.0025
Trypanosoma brucei thymidylate kinase, putative 0.0388 0.04 0.04
Echinococcus multilocularis neuropeptide receptor 0.0029 0.0024 0.0025
Echinococcus multilocularis telomerase reverse transcriptase subunit 0.001 0.0004 0.0004
Leishmania major ATP-dependent phosphofructokinase 0.0105 0.0103 0.0103
Loa Loa (eye worm) hypothetical protein 0.0012 0.0006 0.0006
Schistosoma mansoni hypothetical protein 0.001 0.0004 0.0004
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0014 0.0008 0.0008
Echinococcus granulosus serotonin receptor 0.0029 0.0024 0.0025
Trypanosoma cruzi thymidylate kinase, putative 0.0388 0.04 0.04
Echinococcus multilocularis G protein coupled receptor 139 0.0029 0.0024 0.0025
Loa Loa (eye worm) hypothetical protein 0.0029 0.0024 0.0025
Echinococcus multilocularis Regulator of G protein signaling 20 0.0019 0.0013 0.0013
Trypanosoma cruzi DNA polymerase epsilon catalytic subunit, putative 0.0015 0.0009 0.0009
Trichomonas vaginalis DNA helicase recq, putative 0.0021 0.0015 0.0032
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0016 0.001 0.0229
Echinococcus granulosus tachykinin peptides receptor 99D 0.0029 0.0024 0.0025
Schistosoma mansoni opsin-like receptor 0.0029 0.0024 0.0025
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0028 0.0023 0.03
Trypanosoma brucei multidrug resistance protein E 0.0031 0.0025 0.0025
Echinococcus multilocularis regulator of G protein signaling 3 0.0019 0.0013 0.0013
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0023 0.0017 0.0017
Loa Loa (eye worm) ATP-binding cassette sub-family B member 2 0.0007 0 0.0001
Brugia malayi ORL1-like opioid receptor 0.0029 0.0024 0.0025
Schistosoma mansoni biogenic amine receptor 0.0029 0.0024 0.0025
Echinococcus granulosus beta-adrenergic receptor kinase 0.0019 0.0013 0.0013
Onchocerca volvulus 0.0029 0.0024 0.0024
Loa Loa (eye worm) hypothetical protein 0.0019 0.0013 0.0013
Brugia malayi RNA binding protein 0.0068 0.0064 0.0067
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0013 0.0013
Echinococcus multilocularis rhodopsin orphan GPCR 0.0029 0.0024 0.0025
Echinococcus granulosus regulator of G protein signaling 7 0.0019 0.0013 0.0013
Brugia malayi Dopamine receptor 0.0029 0.0024 0.0025
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0203 0.0206 0.0215
Brugia malayi neuropeptide F receptor 0.0029 0.0024 0.0025
Loa Loa (eye worm) TAR-binding protein 0.0068 0.0064 0.0067
Plasmodium falciparum plasmepsin VIII, putative 0.0014 0.0008 0.0008
Trypanosoma brucei DNA polymerase IV, putative 0.0021 0.0015 0.0014
Brugia malayi multidrug resistance related protein 1 0.0031 0.0025 0.0026
Schistosoma mansoni protein kinase 0.001 0.0004 0.0004
Echinococcus granulosus cpg binding protein 0.0033 0.0028 0.0029
Mycobacterium tuberculosis Bacterioferritin BfrB 0.0008 0.0002 0.0001
Brugia malayi hypothetical protein 0.001 0.0004 0.0004
Plasmodium vivax DNA polymerase alpha, putative 0.0044 0.0039 0.0038
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.0006 0.0013
Trypanosoma cruzi UMP-CMP kinase, mitochondrial, putative 0.0152 0.0153 0.0153
Brugia malayi Cytochrome P450 family protein 0.0012 0.0006 0.0006
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0029 0.0024 0.0025
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.001 0.001
Echinococcus multilocularis RNA directed DNA polymerase (reverse transcriptase) 0.001 0.0004 0.0004
Trypanosoma cruzi thymidine kinase, putative 0.0519 0.0537 0.0537
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0029 0.0024 0.0025
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0015 0.0014
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0007 0 0.0001
Mycobacterium tuberculosis Probable thymidylate synthase ThyA (ts) (TSASE) 0.9172 0.9606 1
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0015 0.0014
Echinococcus granulosus RNA directed DNA polymerase 0.001 0.0004 0.0004
Trichomonas vaginalis PIKK family atypical protein kinase 0.0031 0.0026 0.0057
Echinococcus granulosus rhodopsin orphan GPCR 0.0029 0.0024 0.0025
Trypanosoma cruzi ribonuclease H1, putative 0.0045 0.004 0.004
Schistosoma mansoni multidrug resistance protein 0.0031 0.0025 0.0026
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0068 0.0064 0.0067
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0031 0.0026 0.0026
Loa Loa (eye worm) hypothetical protein 0.0029 0.0024 0.0025
Brugia malayi Dihydrofolate reductase 0.0717 0.0744 0.0775
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0029 0.0024 0.0025
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0007 0 0.0001
Brugia malayi regulator of G-protein signaling egl-10 0.0019 0.0013 0.0013
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0009 0.0002 0.0002
Echinococcus granulosus serine:threonine protein kinase SMG1 0.0011 0.0005 0.0005
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0016 0.001 0.001
Entamoeba histolytica P-glycoprotein 6, putative 0.0007 0 0.0009
Trichomonas vaginalis conserved hypothetical protein 0.0007 0 0.0001
Onchocerca volvulus DNA polymerase alpha catalytic subunit homolog 0.0074 0.0071 0.0073
Echinococcus multilocularis rhodopsin orphan GPCR 0.0029 0.0024 0.0025
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0021 0.0015 0.0032
Entamoeba histolytica P-glycoprotein 5, putative 0.0007 0 0.0009
Brugia malayi Pao retrotransposon peptidase family protein 0.001 0.0004 0.0004
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0007 0 0.0001
Trypanosoma cruzi cytochrome P450, putative 0.0012 0.0006 0.0006
Brugia malayi FAT domain containing protein 0.0009 0.0002 0.0002
Entamoeba histolytica phosphofructokinase, putative 0.0105 0.0103 0.1919
Brugia malayi hypothetical protein 0.0029 0.0024 0.0025
Echinococcus multilocularis cpg binding protein 0.0033 0.0028 0.0029
Loa Loa (eye worm) phosphatidylinositol 3 0.002 0.0014 0.0014
Leishmania major DNA polymerase eta, putative 0.0048 0.0044 0.0044
Trichomonas vaginalis ABC transporter, half transporter, putative 0.0007 0 0.0001
Giardia lamblia MRP-like ABC transporter 0.0031 0.0025 0.0463
Leishmania major GTP-binding protein, putative 0.0023 0.0017 0.0017
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0019 0.0013 0.0013
Loa Loa (eye worm) hypothetical protein 0.0037 0.0031 0.0033
Echinococcus granulosus axis inhibition protein axin 0.0019 0.0013 0.0013
Echinococcus granulosus biogenic amine 5HT receptor 0.0029 0.0024 0.0025
Loa Loa (eye worm) hypothetical protein 0.0029 0.0024 0.0025
Echinococcus multilocularis axis inhibition protein axin 0.0019 0.0013 0.0013
Echinococcus multilocularis dihydrofolate reductase 0.0717 0.0744 0.0775
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0007 0 0.0001
Schistosoma mansoni amine GPCR 0.0029 0.0024 0.0025
Schistosoma mansoni ferritin 0.0008 0.0002 0.0002
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0105 0.0103 0.0107
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0028 0.0023 0.0424
Trypanosoma brucei ingi protein (ORF1) 0.0055 0.0051 0.005
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0009 0.0002 0.0002
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0105 0.0103 0.2545
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0014 0.003
Leishmania major ATP-binding cassette protein subfamily C, member 2, putative 0.0031 0.0025 0.0025
Schistosoma mansoni biogenic amine (5HT) receptor 0.0029 0.0024 0.0025
Brugia malayi CXXC zinc finger family protein 0.0031 0.0026 0.0027
Loa Loa (eye worm) multidrug resistance protein 3 0.0007 0 0.0001
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0016 0.001 0.001
Giardia lamblia Ribonuclease H 0.0045 0.004 0.0739
Toxoplasma gondii eukaryotic aspartyl protease superfamily protein 0.0014 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.0029 0.0024 0.0025
Echinococcus granulosus regulator of G protein signaling 3 0.0019 0.0013 0.0013
Trypanosoma cruzi dihydrofolate reductase-thymidylate synthase 0.9548 1 1
Brugia malayi hypothetical protein 0.0029 0.0024 0.0025
Schistosoma mansoni biogenic amine (5HT) receptor 0.0029 0.0024 0.0025
Loa Loa (eye worm) intermediate filament protein 0.0026 0.0021 0.0021
Schistosoma mansoni cathepsin D (A01 family) 0.0174 0.0175 0.0182
Echinococcus multilocularis rhodopsin orphan GPCR 0.0029 0.0024 0.0025
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0029 0.0024 0.0025
Loa Loa (eye worm) aspartyl protease 6 0.0014 0.0008 0.0008
Trichomonas vaginalis PIKK family atypical protein kinase 0.0011 0.0005 0.001
Schistosoma mansoni smad1 5 8 and 0.0017 0.0011 0.0011
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0016 0.001 0.001
Echinococcus multilocularis dna polymerase epsilon catalytic subunit a 0.0015 0.0009 0.0009
Entamoeba histolytica DNA polymerase alpha catalytic subunit, putative 0.0015 0.0009 0.0168
Echinococcus granulosus snurportin 1 0.0328 0.0337 0.035
Plasmodium vivax importin-beta 2, putative 0.0031 0.0025 0.0025
Schistosoma mansoni hypothetical protein 0.0328 0.0337 0.035
Trypanosoma cruzi trypanothione reductase, putative 0.0016 0.001 0.001
Echinococcus multilocularis rhodopsin orphan GPCR 0.0029 0.0024 0.0025
Brugia malayi Pao retrotransposon peptidase family protein 0.001 0.0004 0.0004
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0014 0.003
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0029 0.0024 0.0025
Echinococcus granulosus GTP binding nuclear protein Ran 0.0023 0.0017 0.0017
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.002 0.0014 0.0014
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0019 0.0013 0.0013
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0013 0.0013
Entamoeba histolytica P-glycoprotein-2, putative 0.0007 0 0.0004
Schistosoma mansoni fkbp-rapamycin associated protein 0.0011 0.0005 0.0005
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0023 0.0017 0.0017
Echinococcus granulosus regulator of G protein signaling 3 0.0019 0.0013 0.0013
Schistosoma mansoni axis inhibition protein axin 0.0019 0.0013 0.0013
Loa Loa (eye worm) hypothetical protein 0.0008 0.0002 0.0002
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0007 0 0.0001
Trichomonas vaginalis DNA helicase recq1, putative 0.0021 0.0015 0.0032
Brugia malayi dihydrofolate reductase family protein 0.0717 0.0744 0.0775
Loa Loa (eye worm) hypothetical protein 0.0029 0.0024 0.0025
Brugia malayi glutathione reductase 0.0046 0.0041 0.0042
Trichomonas vaginalis conserved hypothetical protein 0.0007 0 0.0001
Trichomonas vaginalis conserved hypothetical protein 0.0007 0 0.0001
Brugia malayi follicle stimulating hormone receptor 0.0253 0.0259 0.0269
Loa Loa (eye worm) hypothetical protein 0.0031 0.0025 0.0026
Schistosoma mansoni cathepsin D (A01 family) 0.0174 0.0175 0.0182
Loa Loa (eye worm) hypothetical protein 0.0029 0.0024 0.0025
Treponema pallidum ribonuclease H (rnhA) 0.0045 0.004 0.0959
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.002 0.0014 0.0014
Echinococcus granulosus sex peptide receptor 0.0029 0.0024 0.0025
Loa Loa (eye worm) hypothetical protein 0.0029 0.0024 0.0025
Schistosoma mansoni thymidylate kinase 0.0388 0.04 0.0416
Brugia malayi Pao retrotransposon peptidase family protein 0.001 0.0004 0.0004
Treponema pallidum NADH oxidase 0.0016 0.001 0.0199
Plasmodium falciparum plasmepsin X 0.0014 0.0008 0.0008
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0029 0.0024 0.0025
Treponema pallidum hypothetical protein 0.0016 0.0009 0.0192
Toxoplasma gondii non-specific serine/threonine protein kinase 0.0012 0.0006 0.0006
Giardia lamblia Reverse transcriptase/endonuclease, putative 0.001 0.0004 0.0065
Echinococcus granulosus expressed protein 0.0008 0.0002 0.0002
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0019 0.0013 0.0013
Entamoeba histolytica P-glycoprotein-2, putative 0.0007 0 0.0009
Giardia lamblia Reverse transcriptase/endonuclease, putative 0.001 0.0004 0.0065
Echinococcus granulosus neuropeptide FF receptor 2 0.0029 0.0024 0.0025
Schistosoma mansoni histamine h1 receptor 0.0029 0.0024 0.0025
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0007 0 0.0001
Loa Loa (eye worm) 6-phosphofructokinase 0.0105 0.0103 0.0107
Loa Loa (eye worm) hypothetical protein 0.0026 0.002 0.0021
Onchocerca volvulus 0.001 0.0004 0.0003
Trichomonas vaginalis DNA polymerase alpha catalytic subunit, putative 0.0015 0.0009 0.0019
Mycobacterium ulcerans bacterioferritin BfrA 0.0008 0.0002 0.0001
Echinococcus granulosus g protein coupled receptor 0.0029 0.0024 0.0025
Leishmania major hypothetical protein, conserved 0.0152 0.0153 0.0153
Wolbachia endosymbiont of Brugia malayi hypothetical protein 0.0016 0.0009 0.0221
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0009 0.0002 0.0002
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0029 0.0024 0.0025
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0015 0.0014
Mycobacterium ulcerans thymidylate kinase 0.0388 0.04 0.0416
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0007 0 0.0001
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0014 0.0008 0.0008
Echinococcus multilocularis tar DNA binding protein 0.0068 0.0064 0.0067
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0328 0.0337 0.035
Echinococcus granulosus ferritin 0.0008 0.0002 0.0002
Brugia malayi sulfakinin receptor protein 0.0029 0.0024 0.0025
Schistosoma mansoni hypothetical protein 0.0445 0.0459 0.0478
Loa Loa (eye worm) hypothetical protein 0.0019 0.0013 0.0013
Leishmania major pentamidine resistance protein 1 0.0031 0.0025 0.0025
Echinococcus multilocularis thioredoxin glutathione reductase 0.0046 0.0041 0.0042
Schistosoma mansoni phosphoglucomutase 0.0045 0.004 0.0041
Onchocerca volvulus 0.0029 0.0024 0.0024
Entamoeba histolytica DNA polymerase delta catalytic subunit, putative 0.0015 0.0009 0.0161
Schistosoma mansoni dihydrofolate reductase 0.0717 0.0744 0.0775
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0015 0.0014
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0016 0.001 0.001
Brugia malayi Pao retrotransposon peptidase family protein 0.001 0.0004 0.0004
Echinococcus multilocularis regulator of G protein signaling 7 0.0019 0.0013 0.0013
Plasmodium vivax aspartyl protease, putative 0.0014 0.0008 0.0007
Echinococcus granulosus neuropeptides capa receptor 0.0029 0.0024 0.0025
Echinococcus granulosus g-protein coupled receptor 0.0029 0.0024 0.0025
Onchocerca volvulus 0.0231 0.0235 0.0245
Schistosoma mansoni DNA polymerase epsilon catalytic subunit 0.0015 0.0009 0.0009
Echinococcus granulosus mothers against decapentaplegic 5 0.0017 0.0011 0.0011
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0014 0.0008 0.0008
Leishmania major ribonuclease H1, putative 0.0045 0.004 0.004
Mycobacterium tuberculosis Probable oxidoreductase 0.0116 0.0114 0.0119
Loa Loa (eye worm) hypothetical protein 0.0029 0.0024 0.0025
Echinococcus multilocularis expressed protein 0.0008 0.0002 0.0002
Schistosoma mansoni tar DNA-binding protein 0.0068 0.0064 0.0067
Loa Loa (eye worm) DNA polymerase epsilon catalytic subunit 0.0008 0.0002 0.0002
Toxoplasma gondii aspartyl proteinase (eimepsin), putative 0.0059 0.0055 0.0055
Entamoeba histolytica Phosphatidylinositol 3- and 4-kinase family 0.0023 0.0017 0.0315
Echinococcus granulosus neuropeptide Y receptor 0.0029 0.0024 0.0025
Mycobacterium leprae PROBABLE THYMIDYLATE SYNTHASE THYA (TS) (TSASE) 0.9172 0.9606 1
Echinococcus multilocularis PIK kinase, FAT and Armadillo domain containing protein 0.0009 0.0002 0.0002
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0011 0.0005 0.0005
Schistosoma mansoni Smad4 0.0007 0.0001 0.0001
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0013 0.0028
Brugia malayi G protein-coupled receptor 0.0029 0.0024 0.0025
Schistosoma mansoni growth hormone secretagogue receptor 0.0029 0.0024 0.0025
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0007 0 0.0001
Trypanosoma cruzi thymidine kinase, putative 0.0519 0.0537 0.0537
Plasmodium vivax SET domain protein, putative 0.003 0.0024 0.0024
Trichomonas vaginalis PIKK family atypical protein kinase 0.0007 0.0001 0.0002
Schistosoma mansoni biogenic amine receptor 0.0029 0.0024 0.0025
Trypanosoma cruzi target of rapamycin kinase 3 0.002 0.0014 0.0014
Loa Loa (eye worm) TYRA-2 protein 0.0029 0.0024 0.0025
Loa Loa (eye worm) hypothetical protein 0.0026 0.0021 0.0021
Entamoeba histolytica hypothetical protein 0.0019 0.0013 0.0235
Entamoeba histolytica P-glycoprotein 6, putative 0.0007 0 0.0009
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.003 0.0024 0.0025
Echinococcus multilocularis RNA directed DNA polymerase (reverse transcriptase) 0.001 0.0004 0.0004
Entamoeba histolytica P-glycoprotein-2 0.0007 0 0.0009
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0028 0.0022 0.0023
Giardia lamblia NADH oxidase lateral transfer candidate 0.0016 0.001 0.0175
Echinococcus granulosus DNA polymerase alpha catalytic subunit 0.0054 0.005 0.0051
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0016 0.001 0.001
Plasmodium falciparum DNA polymerase alpha catalytic subunit A 0.0015 0.0009 0.0009
Schistosoma mansoni smad 0.0007 0.0001 0.0001
Toxoplasma gondii thymidylate kinase 0.0388 0.04 0.04
Schistosoma mansoni neuropeptide F-like receptor 0.0029 0.0024 0.0025
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0034 0.0029 0.0029
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0029 0.0024 0.0025
Schistosoma mansoni serine/threonine protein kinase 0.0019 0.0013 0.0013
Trypanosoma brucei trypanothione reductase 0.0046 0.0041 0.004
Schistosoma mansoni tar DNA-binding protein 0.0068 0.0064 0.0067
Entamoeba histolytica phosphofructokinase, putative 0.0105 0.0103 0.1919
Schistosoma mansoni DNA helicase recq1 0.0009 0.0002 0.0002
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0029 0.0024 0.0025
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0011 0.0005 0.0005
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0013 0.0006 0.0006
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.002 0.0014 0.0013
Loa Loa (eye worm) hypothetical protein 0.0029 0.0024 0.0025
Brugia malayi putative neuropeptide receptor NPR1 0.0029 0.0024 0.0025
Loa Loa (eye worm) hypothetical protein 0.0029 0.0024 0.0025
Loa Loa (eye worm) MH2 domain-containing protein 0.0245 0.0249 0.026
Schistosoma mansoni DNA polymerase delta catalytic subunit 0.0015 0.0009 0.0009
Onchocerca volvulus 0.0026 0.0021 0.0021
Schistosoma mansoni cpg binding protein 0.0033 0.0028 0.0029
Trypanosoma cruzi DNA polymerase delta catalytic subunit, putative 0.0015 0.0009 0.0009
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0009 0.0002 0.0002
Giardia lamblia CDC8 0.0388 0.04 0.7445
Brugia malayi Intermediate filament tail domain containing protein 0.0026 0.0021 0.0021
Loa Loa (eye worm) hypothetical protein 0.0012 0.0005 0.0005
Onchocerca volvulus DNA polymerase homolog 0.0015 0.0009 0.0008
Mycobacterium ulcerans FAD-dependent thymidylate synthase 0.5019 0.5254 0.5469
Onchocerca volvulus 0.0029 0.0024 0.0024
Trypanosoma brucei DNA polymerase epsilon catalytic subunit, putative 0.0015 0.0009 0.0008
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0014 0.0008 0.0008
Schistosoma mansoni ran 0.0023 0.0017 0.0017
Brugia malayi Dopamine receptor protein 1 0.0029 0.0024 0.0025
Brugia malayi Cytochrome P450 family protein 0.0012 0.0006 0.0006
Echinococcus multilocularis thymidylate synthase 0.9172 0.9606 1
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0029 0.0024 0.0025
Schistosoma mansoni amine GPCR 0.0029 0.0024 0.0025
Onchocerca volvulus 0.0029 0.0024 0.0024
Echinococcus multilocularis neuropeptide receptor 0.0029 0.0024 0.0025
Toxoplasma gondii DNA polymerase family B protein 0.0015 0.0009 0.0009
Leishmania major ABC-thiol transporter 0.0031 0.0025 0.0025
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0253 0.0259 0.0269
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0014 0.003
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0021 0.0015 0.0015
Schistosoma mansoni ataxia telangiectasia mutated (atm) 0.0011 0.0005 0.0005
Brugia malayi hypothetical protein 0.0029 0.0024 0.0025
Brugia malayi Bloom's syndrome protein homolog 0.0021 0.0015 0.0015
Brugia malayi F/Y-rich N-terminus family protein 0.0011 0.0004 0.0004
Plasmodium falciparum thymidylate kinase 0.0388 0.04 0.04
Trichomonas vaginalis ran, putative 0.0023 0.0017 0.0037
Loa Loa (eye worm) histone methyltransferase 0.0011 0.0004 0.0004
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0014 0.0008 0.0008
Brugia malayi Pao retrotransposon peptidase family protein 0.001 0.0004 0.0004
Plasmodium vivax plasmepsin V, putative 0.0014 0.0008 0.0007
Entamoeba histolytica hypothetical protein 0.0019 0.0013 0.0235
Echinococcus multilocularis fmrfamide receptor 0.0029 0.0024 0.0025
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0021 0.0015 0.0015
Echinococcus granulosus 6 phosphofructokinase 0.0105 0.0103 0.0107
Trypanosoma brucei target of rapamycin kinase 3, putative 0.002 0.0014 0.0013
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0007 0 0.0001
Loa Loa (eye worm) 6-phosphofructokinase 0.0105 0.0103 0.0107
Loa Loa (eye worm) MH2 domain-containing protein 0.0007 0.0001 0.0001
Echinococcus multilocularis smad 0.0017 0.0011 0.0011
Loa Loa (eye worm) nuclear factor I 0.0009 0.0003 0.0003
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0014 0.003
Echinococcus granulosus somatostatin receptor 0.0029 0.0024 0.0025
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.002 0.0014 0.0254
Trypanosoma brucei DNA polymerase zeta catalytic subunit, putative 0.0015 0.0009 0.0008
Echinococcus granulosus alpha 1A adrenergic receptor 0.0029 0.0024 0.0025
Trypanosoma brucei DNA polymerase kappa, putative 0.0014 0.0008 0.0008
Echinococcus granulosus RNA directed DNA polymerase reverse transcriptase 0.001 0.0004 0.0004
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0007 0 0.0001
Wolbachia endosymbiont of Brugia malayi bacterioferritin/cytochrome b1 0.0008 0.0002 0.003
Schistosoma mansoni neuropeptide receptor 0.0029 0.0024 0.0025
Schistosoma mansoni apoferritin-2 0.0008 0.0002 0.0002
Plasmodium vivax aspartyl protease, putative 0.0014 0.0008 0.0007
Schistosoma mansoni neuropeptide receptor 0.0029 0.0024 0.0025
Treponema pallidum thymidylate kinase (tmk) 0.0388 0.04 1
Trichomonas vaginalis reverse transcriptases, putative 0.001 0.0004 0.0008
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.0019 0.0013 0.0028
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0007 0 0.0001
Mycobacterium tuberculosis Dihydrofolate reductase DfrA (DHFR) (tetrahydrofolate dehydrogenase) 0.0717 0.0744 0.0775
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0021 0.0015 0.0015
Brugia malayi MH1 domain containing protein 0.0009 0.0003 0.0003
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0028 0.0023 0.005
Schistosoma mansoni Smad4 0.0017 0.0011 0.0011
Echinococcus multilocularis regulator of G protein signaling 3 0.0019 0.0013 0.0013
Loa Loa (eye worm) hypothetical protein 0.0007 0 0.0001
Echinococcus multilocularis axis inhibition protein axin 0.0019 0.0013 0.0013
Schistosoma mansoni hypothetical protein 0.0029 0.0024 0.0025
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0007 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0019 0.0013 0.0013
Brugia malayi ImpB/MucB/SamB family protein 0.0021 0.0015 0.0015
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.002 0.0014 0.0014
Echinococcus multilocularis g protein coupled receptor 0.0029 0.0024 0.0025
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0017 0.0011 0.0011
Schistosoma mansoni opsin-like receptor 0.0029 0.0024 0.0025
Onchocerca volvulus 0.0029 0.0024 0.0024
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0016 0.001 0.001
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0014 0.003
Trichomonas vaginalis conserved hypothetical protein 0.0007 0.0001 0.0002
Brugia malayi AKH receptor 0.0029 0.0024 0.0025
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0023 0.0017 0.0017
Schistosoma mansoni smad 0.0017 0.0011 0.0011
Mycobacterium tuberculosis Probable thymidylate synthase ThyX (ts) (TSase) 0.5019 0.5254 0.5469
Echinococcus multilocularis multidrug resistance associated protein 4 0.0023 0.0018 0.0018
Echinococcus granulosus thymidylate kinase 0.0388 0.04 0.0416
Schistosoma mansoni biogenic amine receptor 0.0029 0.0024 0.0025
Echinococcus granulosus dnaJ subfamily B 0.0445 0.0459 0.0478
Brugia malayi MH2 domain containing protein 0.0017 0.0011 0.0011
Schistosoma mansoni ferritin 0.0008 0.0002 0.0002
Brugia malayi DNA polymerase delta catalytic subunit 0.0015 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.0029 0.0024 0.0025
Loa Loa (eye worm) glutathione reductase 0.0046 0.0041 0.0043
Trichomonas vaginalis conserved hypothetical protein 0.0007 0 0.0001
Trichomonas vaginalis set domain proteins, putative 0.0231 0.0235 0.0516
Trypanosoma brucei SLACS reverse transcriptase, putative 0.001 0.0004 0.0003
Echinococcus granulosus peptide allatostatin:somatostatin 0.0029 0.0024 0.0025
Brugia malayi Pao retrotransposon peptidase family protein 0.001 0.0004 0.0004
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0009 0.0002 0.0002
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0029 0.0024 0.0025
Loa Loa (eye worm) hypothetical protein 0.0029 0.0024 0.0025
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0029 0.0024 0.0025
Echinococcus multilocularis g protein coupled receptor 0.0029 0.0024 0.0025
Loa Loa (eye worm) RecQ helicase 0.0021 0.0015 0.0015
Loa Loa (eye worm) hypothetical protein 0.0013 0.0006 0.0007
Trypanosoma brucei DNA polymerase alpha catalytic subunit 0.0024 0.0018 0.0017
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0013 0.0013
Onchocerca volvulus 0.0029 0.0024 0.0024
Trypanosoma brucei p-glycoprotein 0.0031 0.0025 0.0025
Schistosoma mansoni alpha-1 adrenergic receptor 0.0029 0.0024 0.0025
Echinococcus granulosus smad 0.0017 0.0011 0.0011
Brugia malayi phosphofructokinase 0.0105 0.0103 0.0107
Mycobacterium ulcerans bacterioferritin BfrB 0.0008 0.0002 0.0001
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0104 0.0102 0.0106
Loa Loa (eye worm) hypothetical protein 0.0029 0.0024 0.0025
Brugia malayi reverse transcriptase 0.001 0.0004 0.0004
Toxoplasma gondii NADPH-glutathione reductase 0.0016 0.001 0.001
Brugia malayi RNase H family protein 0.0045 0.004 0.0041
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0014 0.003
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0029 0.0024 0.0025
Trichomonas vaginalis phosphofructokinase, putative 0.0028 0.0023 0.005
Echinococcus granulosus neuropeptide receptor A26 0.0029 0.0024 0.0025
Trichomonas vaginalis reverse transcriptase [C. elegans], putative 0.001 0.0004 0.0008
Loa Loa (eye worm) hypothetical protein 0.0029 0.0024 0.0025
Plasmodium falciparum thioredoxin reductase 0.0046 0.0041 0.0041
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0011 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0029 0.0024 0.0025
Echinococcus multilocularis serotonin receptor 0.0029 0.0024 0.0025
Trypanosoma brucei multidrug resistance-associated protein, putative 0.0031 0.0025 0.0025
Schistosoma mansoni terminal deoxycytidyl transferase 0.0021 0.0015 0.0015
Brugia malayi Regulator of G protein signaling domain containing protein 0.0019 0.0013 0.0013
Trypanosoma brucei cytochrome P450, putative 0.0012 0.0006 0.0005
Echinococcus granulosus mothers against decapentaplegic 2 0.0007 0.0001 0.0001
Echinococcus multilocularis rhodopsin orphan GPCR 0.0029 0.0024 0.0025
Loa Loa (eye worm) hypothetical protein 0.0029 0.0024 0.0025
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0009 0.0002 0.0002
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0013 0.0028
Trichomonas vaginalis abcb9, putative 0.0007 0 0.0001
Trypanosoma brucei SLACS retrotransposable element (part), putative 0.001 0.0004 0.0003
Echinococcus granulosus hypothetical protein 0.0029 0.0024 0.0025
Loa Loa (eye worm) hypothetical protein 0.0059 0.0055 0.0057
Loa Loa (eye worm) ABC transporter 0.0007 0 0.0001
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0014 0.0008 0.0008
Leishmania major ATP-binding cassette protein subfamily C, member 1, putative 0.0031 0.0025 0.0025
Schistosoma mansoni serine/threonine protein kinase 0.0019 0.0013 0.0013
Trypanosoma brucei DNA polymerase eta, putative 0.0048 0.0044 0.0043
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0012 0.0006 0.0005
Loa Loa (eye worm) hypothetical protein 0.0012 0.0006 0.0006
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0009 0.0002 0.0002
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0014 0.003
Schistosoma mansoni scy1(yeast) protein kinase-like 0.001 0.0004 0.0004
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0014 0.0008 0.0007
Echinococcus multilocularis dna polymerase kappa 0.0021 0.0015 0.0015
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0007 0 0.0001
Trichomonas vaginalis DNA polymerase zeta catalytic subunit, putative 0.0015 0.0009 0.0019
Plasmodium vivax aspartyl proteinase, putative 0.0059 0.0055 0.0054
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0054 0.0049 0.0051
Brugia malayi ImpB/MucB/SamB family protein 0.0048 0.0044 0.0045
Echinococcus multilocularis importin subunit beta 1 0.0031 0.0025 0.0026
Trichomonas vaginalis phosphofructokinase, putative 0.0105 0.0103 0.0226
Brugia malayi reverse transcriptase 0.001 0.0004 0.0004
Echinococcus multilocularis expressed protein 0.0363 0.0374 0.0389
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0029 0.0024 0.0025
Brugia malayi GnHR receptor homolog 0.0029 0.0024 0.0025
Leishmania major thymidine kinase, putative 0.0519 0.0537 0.0537
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0013 0.0028
Chlamydia trachomatis hypothetical protein 0.0016 0.0009 0.0119
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0016 0.001 0.001
Schistosoma mansoni tar DNA-binding protein 0.0068 0.0064 0.0067
Echinococcus multilocularis serine protein kinase ATM 0.0011 0.0005 0.0005
Entamoeba histolytica multidrug resistance protein, putative 0.0031 0.0025 0.0467
Trichomonas vaginalis ABC transporter, half transporter, putative 0.0007 0 0.0001
Schistosoma mansoni ferritin light chain 0.0008 0.0002 0.0002
Echinococcus granulosus RNA directed DNA polymerase reverse transcriptase 0.001 0.0004 0.0004
Schistosoma mansoni 6-phosphofructokinase 0.0105 0.0103 0.0107
Brugia malayi Pre-SET motif family protein 0.0203 0.0206 0.0214
Loa Loa (eye worm) hypothetical protein 0.0007 0 0.0001
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0029 0.0024 0.0025
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0013 0.0013
Loa Loa (eye worm) hypothetical protein 0.0074 0.0071 0.0074
Brugia malayi MH2 domain containing protein 0.0017 0.0011 0.0011
Toxoplasma gondii thioredoxin reductase 0.0046 0.0041 0.0041
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0016 0.001 0.001
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0009 0.0002 0.0002
Giardia lamblia Multidrug resistance-associated protein 1 0.003 0.0025 0.0458
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0007 0 0.0001
Trypanosoma cruzi importin beta-1 subunit, putative 0.0025 0.0019 0.0019
Trypanosoma cruzi hypothetical protein, conserved 0.001 0.0004 0.0004
Chlamydia trachomatis dihydrofolate reductase 0.0717 0.0744 1
Brugia malayi DNA polymerase family B, exonuclease domain containing protein 0.0015 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.0017 0.0011 0.0011
Echinococcus granulosus tm gpcr rhodopsin 0.0029 0.0024 0.0025
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0007 0 0.0001
Toxoplasma gondii DNA polymerase 0.0015 0.0009 0.0009
Echinococcus granulosus neuropeptide receptor 0.0029 0.0024 0.0025
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0002 0.0004
Loa Loa (eye worm) hypothetical protein 0.0029 0.0024 0.0025
Leishmania major DNA polymerase kappa, putative 0.0021 0.0015 0.0015
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0009 0.0002 0.0002
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0074 0.0071 0.0074
Giardia lamblia Thymidine kinase 0.0519 0.0537 1
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0031 0.0026 0.0025
Echinococcus granulosus rhodopsin orphan GPCR 0.0029 0.0024 0.0025
Schistosoma mansoni neuropeptide receptor 0.0029 0.0024 0.0025
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0021 0.0015 0.0015
Trypanosoma cruzi DNA polymerase kappa, putative 0.0021 0.0015 0.0015
Brugia malayi RNA recognition motif domain containing protein 0.0068 0.0064 0.0067
Loa Loa (eye worm) hypothetical protein 0.0029 0.0024 0.0025
Trypanosoma brucei ingi protein (ORF1) 0.0055 0.0051 0.005
Echinococcus multilocularis somatostatin receptor 0.0029 0.0024 0.0025
Treponema pallidum hypothetical protein 0.0016 0.0009 0.0192
Trichomonas vaginalis conserved hypothetical protein 0.0007 0 0.0001
Trypanosoma brucei unspecified product 0.0014 0.0008 0.0008
Trypanosoma cruzi DNA polymerase kappa, putative 0.0021 0.0015 0.0015
Entamoeba histolytica recQ family helicase, putative 0.0011 0.0005 0.0087
Leishmania major deoxyuridine triphosphatase, putative,dUTP diphosphatase 0.04 0.0412 0.0412
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0014 0.003
Toxoplasma gondii bifunctional dihydrofolate reductase-thymidylate synthase 0.9548 1 1
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0029 0.0024 0.0025
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0029 0.0024 0.0025
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.002 0.0014 0.0014
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.0009 0.0002 0.0002
Trichomonas vaginalis conserved hypothetical protein 0.0007 0 0.0001
Loa Loa (eye worm) hypothetical protein 0.0014 0.0008 0.0008
Schistosoma mansoni ferritin 0.0008 0.0002 0.0002
Toxoplasma gondii FATC domain-containing protein 0.0011 0.0005 0.0005
Treponema pallidum hypothetical protein 0.0016 0.0009 0.0192
Trichomonas vaginalis ABC transporter, putative 0.0007 0 0.0001
Schistosoma mansoni adenoreceptor 0.0029 0.0024 0.0025
Loa Loa (eye worm) hypothetical protein 0.0029 0.0024 0.0025
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.002 0.0014 0.0014
Brugia malayi Tachykinin-like peptides receptor 99D 0.0029 0.0024 0.0025
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.0011 0.0005 0.0005
Trichomonas vaginalis phosphofructokinase, putative 0.0028 0.0023 0.005
Schistosoma mansoni cpg binding protein 0.0031 0.0026 0.0027
Brugia malayi hypothetical protein 0.0014 0.0008 0.0008
Plasmodium vivax plasmepsin IV, putative 0.0059 0.0055 0.0054
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0029 0.0024 0.0025
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0029 0.0024 0.0025
Loa Loa (eye worm) hypothetical protein 0.0009 0.0002 0.0002
Loa Loa (eye worm) DNA-directed DNA polymerase III 0.0015 0.0009 0.0009
Leishmania major DNA polymerase epsilon catalytic subunit, putative 0.0015 0.0009 0.0009
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0029 0.0024 0.0025
Echinococcus granulosus lamin 0.0026 0.0021 0.0021
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0019 0.0013 0.0013
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0054 0.0049 0.0051
Trichomonas vaginalis DNA helicase recq, putative 0.0011 0.0005 0.001
Plasmodium falciparum glutathione reductase 0.0016 0.001 0.001
Brugia malayi Latrophilin receptor protein 2 0.0017 0.0011 0.0011
Leishmania major DNA polymerase eta, putative 0.0034 0.0029 0.0029
Schistosoma mansoni myosin xvIII 0.0029 0.0024 0.0025
Giardia lamblia DNA polymerase epsilon, catalytic subunit 0.0015 0.0009 0.0157
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0016 0.001 0.001
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0007 0 0.0001
Brugia malayi Eukaryotic aspartyl protease family protein 0.0014 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.0029 0.0024 0.0025
Onchocerca volvulus 0.0029 0.0024 0.0024
Trypanosoma brucei thymidylate kinase, putative 0.0388 0.04 0.04
Schistosoma mansoni o-linked n-acetylglucosamine transferase ogt 0.004 0.0035 0.0036
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0013 0.0013
Echinococcus granulosus Regulator of G protein signaling 20 0.0019 0.0013 0.0013
Trichomonas vaginalis conserved hypothetical protein 0.0007 0 0.0001
Echinococcus granulosus g protein coupled receptor 0.0029 0.0024 0.0025
Brugia malayi UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 0.004 0.0035 0.0036
Schistosoma mansoni intermediate filament proteins 0.0026 0.0021 0.0021
Loa Loa (eye worm) hypothetical protein 0.0007 0 0.0001
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0007 0 0.0001
Toxoplasma gondii HEAT repeat-containing protein 0.0031 0.0025 0.0025
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0014 0.003
Mycobacterium tuberculosis Possible maturase 0.001 0.0004 0.0003
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0009 0.0002 0.0002
Trichomonas vaginalis PIKK family atypical protein kinase 0.0011 0.0005 0.001
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0011 0.0005 0.0005
Echinococcus granulosus dna polymerase epsilon catalytic subunit a 0.0015 0.0009 0.0009
Mycobacterium tuberculosis Probable dehydrogenase 0.0104 0.0102 0.0106
Echinococcus granulosus rhodopsin orphan GPCR 0.0029 0.0024 0.0025
Onchocerca volvulus 0.0014 0.0008 0.0007
Loa Loa (eye worm) MH1 domain-containing protein 0.0007 0.0001 0.0001
Echinococcus granulosus axis inhibition protein axin 0.0019 0.0013 0.0013
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0028 0.0023 0.0023
Loa Loa (eye worm) Smad1 0.0017 0.0011 0.0011
Echinococcus multilocularis RNA directed DNA polymerase 0.001 0.0004 0.0004
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0016 0.001 0.001
Echinococcus multilocularis O glycosyltransferase 0.004 0.0035 0.0036
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0016 0.001 0.0009
Schistosoma mansoni ran 0.0023 0.0017 0.0017
Giardia lamblia Multidrug resistance-associated protein 1 0.0031 0.0025 0.0463
Echinococcus granulosus multidrug resistance associated protein 4 0.0023 0.0018 0.0018
Trichomonas vaginalis ABC transporter, putative 0.0007 0 0.0001
Schistosoma mansoni neuropeptide F-like receptor 0.0029 0.0024 0.0025
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0009 0.0002 0.0002
Leishmania major thymidylate kinase-like protein 0.0388 0.04 0.04
Echinococcus multilocularis G-protein coupled receptor, putative 0.0029 0.0024 0.0025
Echinococcus granulosus intermediate filament protein 0.0026 0.0021 0.0021
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0011 0.0005 0.0005
Echinococcus granulosus importin subunit beta 1 0.0031 0.0025 0.0026
Onchocerca volvulus 0.0029 0.0024 0.0024
Trichomonas vaginalis DNA polymerase eta, putative 0.0021 0.0015 0.0032
Loa Loa (eye worm) ABC transporter 0.0007 0 0.0001
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0028 0.0023 0.042
Loa Loa (eye worm) hypothetical protein 0.0029 0.0024 0.0025
Loa Loa (eye worm) hypothetical protein 0.0019 0.0013 0.0013
Trichomonas vaginalis reverse transcriptases, putative 0.001 0.0004 0.0008
Brugia malayi ABC transporter transmembrane region family protein 0.0031 0.0025 0.0026
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.002 0.0014 0.0014
Echinococcus multilocularis neuropeptide Y receptor 0.0029 0.0024 0.0025
Brugia malayi hypothetical protein 0.001 0.0004 0.0004
Echinococcus multilocularis multidrug resistance associated protein 1 0.0031 0.0025 0.0026
Toxoplasma gondii ribonuclease HI protein 0.0045 0.004 0.004
Echinococcus multilocularis Smad4 0.0017 0.0011 0.0011
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0029 0.0024 0.0025
Trichomonas vaginalis thymidine kinase, putative 0.0519 0.0537 0.1177
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0025 0.0019 0.0042
Plasmodium vivax bifunctional dihydrofolate reductase-thymidylate synthase, putative 0.9548 1 1
Brugia malayi Smad1 0.0017 0.0011 0.0011
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0013 0.0028
Brugia malayi MH1 domain containing protein 0.0017 0.0011 0.0011
Trichomonas vaginalis PIKK family atypical protein kinase 0.0011 0.0005 0.001
Brugia malayi Dopamine receptor protein 2 0.0029 0.0024 0.0025
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0007 0 0.0001
Giardia lamblia DINP protein human, muc B family 0.0021 0.0015 0.0271
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0007 0 0.0001
Brugia malayi RNase H family protein 0.0045 0.004 0.0041
Mycobacterium ulcerans hypothetical protein 0.0016 0.0009 0.0009
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0029 0.0024 0.0025
Schistosoma mansoni tar DNA-binding protein 0.0068 0.0064 0.0067
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0023 0.0017 0.0017
Echinococcus multilocularis sex peptide receptor 0.0029 0.0024 0.0025
Brugia malayi Serotonin receptor 0.0029 0.0024 0.0025
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0016 0.001 0.0009
Echinococcus granulosus biogenic amine 5HT receptor 0.0029 0.0024 0.0025
Mycobacterium leprae DIHYDROFOLATE REDUCTASE DFRA (DHFR) (TETRAHYDROFOLATE DEHYDROGENASE) 0.0717 0.0744 0.0775
Leishmania major trypanothione reductase 0.0046 0.0041 0.0041
Schistosoma mansoni DNA polymerase zeta catalytic subunit 0.0015 0.0009 0.0009
Plasmodium vivax aspartyl proteinase, putative 0.0014 0.0008 0.0007
Entamoeba histolytica hypothetical protein 0.0011 0.0005 0.0087
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0029 0.0024 0.0025
Trypanosoma brucei Endonuclease-reverse transcriptase/Reverse transcriptase (RNA-dependent DNA polymerase), putative 0.001 0.0004 0.0003
Loa Loa (eye worm) hypothetical protein 0.0012 0.0006 0.0006
Trichomonas vaginalis PIKK family atypical protein kinase 0.0011 0.0005 0.001
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0016 0.001 0.0229
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.001 0.001
Brugia malayi Pepsin A precursor 0.0014 0.0008 0.0008
Echinococcus granulosus rhodopsin orphan GPCR 0.0029 0.0024 0.0025
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0011 0.0005 0.0004
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0074 0.0071 0.0074
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0116 0.0114 0.0119
Brugia malayi hypothetical protein 0.001 0.0004 0.0004
Echinococcus multilocularis DNA polymerase delta catalytic subunit 0.0015 0.0009 0.0009
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0014 0.0008 0.0008
Echinococcus granulosus rhodopsin orphan GPCR 0.0029 0.0024 0.0025
Echinococcus granulosus RNA directed DNA polymerase reverse transcriptase 0.001 0.0004 0.0004
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.003 0.0024 0.0025
Loa Loa (eye worm) hypothetical protein 0.0054 0.0049 0.0051
Loa Loa (eye worm) hypothetical protein 0.0029 0.0024 0.0025
Loa Loa (eye worm) hypothetical protein 0.003 0.0025 0.0026
Echinococcus multilocularis neuropeptide s receptor 0.0029 0.0024 0.0025
Schistosoma mansoni bifunctional dihydrofolate reductase-thymidylate synthase 0.9172 0.9606 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0023 0.0017 0.0037
Brugia malayi MH2 domain containing protein 0.0007 0.0001 0.0001
Loa Loa (eye worm) RNA binding protein 0.0068 0.0064 0.0067
Trypanosoma brucei RNA helicase, putative 0.0449 0.0464 0.0464
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0017 0.0011 0.0011
Loa Loa (eye worm) CYP4Cod1 0.0012 0.0006 0.0006
Trichomonas vaginalis PIKK family atypical protein kinase 0.0012 0.0006 0.0013
Schistosoma mansoni importin beta-1 0.0031 0.0025 0.0026
Echinococcus multilocularis GPCR, family 2 0.0017 0.0011 0.0011
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0016 0.001 0.001
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0007 0 0.0001
Wolbachia endosymbiont of Brugia malayi hypothetical protein 0.0016 0.0009 0.0221
Entamoeba histolytica P-glycoprotein-1 0.0007 0 0.0009
Mycobacterium leprae probable thymidylate kinase Tmk (dTMP KINASE) (THYMIDYLIC ACID KINASE) (TMPK) 0.0388 0.04 0.0416
Brugia malayi MH1 domain containing protein 0.0017 0.0011 0.0011
Echinococcus multilocularis ribonuclease H1 0.0045 0.004 0.0041
Schistosoma mansoni hypothetical protein 0.0449 0.0464 0.0483
Loa Loa (eye worm) CXXC zinc finger family protein 0.0031 0.0026 0.0027
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0028 0.0023 0.0529
Brugia malayi hypothetical protein 0.0019 0.0013 0.0013
Trichomonas vaginalis conserved hypothetical protein 0.0007 0 0.0001
Entamoeba histolytica deoxycytidyl transferase, putative 0.0021 0.0015 0.0276
Loa Loa (eye worm) melatonin receptor type 1A 0.0029 0.0024 0.0025
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0074 0.0071 0.0071
Echinococcus multilocularis serine:threonine protein kinase SMG1 0.0011 0.0005 0.0005
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0029 0.0024 0.0025
Loa Loa (eye worm) hypothetical protein 0.0012 0.0005 0.0005
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0012 0.0005 0.0005
Echinococcus granulosus lamin dm0 0.0026 0.0021 0.0021
Onchocerca volvulus 0.0029 0.0024 0.0024
Loa Loa (eye worm) hypothetical protein 0.0029 0.0024 0.0025
Brugia malayi Pao retrotransposon peptidase family protein 0.001 0.0004 0.0004
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0105 0.0103 0.0103
Loa Loa (eye worm) hypothetical protein 0.0019 0.0013 0.0013
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0017 0.0011 0.0011
Brugia malayi RE15519p 0.0029 0.0024 0.0025
Trichomonas vaginalis taga, putative 0.0007 0 0.0001
Echinococcus granulosus O glycosyltransferase 0.004 0.0035 0.0036
Brugia malayi hypothetical protein 0.0029 0.0024 0.0025
Onchocerca volvulus 0.0031 0.0026 0.0026
Schistosoma mansoni hypothetical protein 0.0037 0.0031 0.0033
Brugia malayi PXA domain containing protein 0.0019 0.0013 0.0013
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0016 0.001 0.001
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0013 0.0006 0.0006
Echinococcus multilocularis RNA directed DNA polymerase (reverse transcriptase) 0.001 0.0004 0.0004
Brugia malayi aspartic protease BmAsp-1, identical 0.0014 0.0008 0.0008
Schistosoma mansoni hypothetical protein 0.0017 0.0011 0.0011
Plasmodium falciparum plasmepsin V 0.0014 0.0008 0.0008
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0029 0.0024 0.0025
Loa Loa (eye worm) hypothetical protein 0.0029 0.0024 0.0025
Echinococcus granulosus thioredoxin glutathione reductase 0.0046 0.0041 0.0042
Trypanosoma cruzi DNA polymerase eta, putative 0.0048 0.0044 0.0044
Plasmodium falciparum thioredoxin reductase 0.0016 0.001 0.001
Echinococcus multilocularis beta adrenergic receptor kinase 0.0019 0.0013 0.0013
Onchocerca volvulus 0.0029 0.0024 0.0024
Trichomonas vaginalis abcb9, putative 0.0007 0 0.0001
Trypanosoma cruzi thymidylate kinase, putative 0.0388 0.04 0.04
Echinococcus granulosus ribonuclease H1 0.0045 0.004 0.0041
Schistosoma mansoni apoferritin-2 0.0008 0.0002 0.0002
Echinococcus granulosus GPCR family 2 0.0017 0.0011 0.0011
Brugia malayi aspartic protease BmAsp-2, identical 0.0014 0.0008 0.0008
Echinococcus multilocularis RNA directed DNA polymerase (reverse transcriptase) 0.001 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0029 0.0024 0.0025
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0029 0.0024 0.0025

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) = 3.2 uM Inhibition against purified human renin ChEMBL. 3309313
IC50 (binding) = 3.2 uM Inhibition against purified human renin ChEMBL. 3309313

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

No external resources registered for this compound

Bibliographic References

1 literature reference was collected for this gene.

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