Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.0133 | 0.3507 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0338 | 1 | 1 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0025 | 0.0094 | 0.5 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0044 | 0.0693 | 0.0693 |
Onchocerca volvulus | 0.0022 | 0 | 0.5 | |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0025 | 0.0094 | 0.5 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0044 | 0.0693 | 0.0693 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0025 | 0.0094 | 0.5 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0044 | 0.0693 | 0.0693 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.0843 | 0.2404 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0044 | 0.0693 | 0.0693 |
Trichomonas vaginalis | spcc417.12 protein, putative | 0.0022 | 0 | 0.5 |
Leishmania major | hypothetical protein, conserved | 0.0025 | 0.0094 | 0.5 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0049 | 0.0843 | 0.2404 |
Mycobacterium ulcerans | carboxylesterase, LipT | 0.0022 | 0 | 0.5 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0049 | 0.0843 | 0.2404 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0044 | 0.0693 | 0.0693 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0022 | 0 | 0.5 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0044 | 0.0693 | 0.0693 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0022 | 0 | 0.5 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0025 | 0.0094 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0351 | 0.1 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0034 | 0.0351 | 0.1 |
Loa Loa (eye worm) | carboxylesterase | 0.0133 | 0.3507 | 1 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0044 | 0.0693 | 0.0693 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0025 | 0.0094 | 0.5 |
Brugia malayi | Carboxylesterase family protein | 0.0133 | 0.3507 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0133 | 0.3507 | 1 |
Echinococcus granulosus | acetylcholinesterase | 0.0133 | 0.3507 | 0.3507 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0025 | 0.0094 | 0.5 |
Echinococcus multilocularis | carboxylesterase 5A | 0.0133 | 0.3507 | 0.3507 |
Echinococcus granulosus | acetylcholinesterase | 0.0133 | 0.3507 | 0.3507 |
Schistosoma mansoni | hypothetical protein | 0.0338 | 1 | 1 |
Onchocerca volvulus | 0.0022 | 0 | 0.5 | |
Onchocerca volvulus | 0.0022 | 0 | 0.5 | |
Echinococcus granulosus | carboxylesterase 5A | 0.0133 | 0.3507 | 0.3507 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0049 | 0.0843 | 0.2404 |
Trichomonas vaginalis | carboxylesterase domain containing protein, putative | 0.0022 | 0 | 0.5 |
Brugia malayi | hypothetical protein | 0.0025 | 0.0094 | 0.0267 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0025 | 0.0094 | 0.5 |
Brugia malayi | Carboxylesterase family protein | 0.0133 | 0.3507 | 1 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0044 | 0.0693 | 0.1976 |
Echinococcus multilocularis | geminin | 0.0338 | 1 | 1 |
Echinococcus multilocularis | acetylcholinesterase | 0.0133 | 0.3507 | 0.3507 |
Mycobacterium tuberculosis | Carboxylesterase LipT | 0.0022 | 0 | 0.5 |
Onchocerca volvulus | 0.0022 | 0 | 0.5 | |
Onchocerca volvulus | 0.0022 | 0 | 0.5 | |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0094 | 0.0267 |
Schistosoma mansoni | hypothetical protein | 0.0034 | 0.0351 | 0.0351 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0133 | 0.3507 | 0.3507 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.0133 | 0.3507 | 1 |
Echinococcus multilocularis | acetylcholinesterase | 0.0133 | 0.3507 | 0.3507 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0044 | 0.0693 | 0.1976 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.