Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0064 | 0.1544 | 1 |
Echinococcus granulosus | para nitrobenzyl esterase | 0.0018 | 0.0213 | 0.0213 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0125 | 0.3334 | 0.5185 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0015 | 0.0141 | 0.0141 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.0039 | 0.0818 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0213 | 0.0331 |
Brugia malayi | Carboxylesterase family protein | 0.0018 | 0.0213 | 0.0331 |
Schistosoma mansoni | tar DNA-binding protein | 0.0066 | 0.1624 | 0.5851 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0213 | 0.0331 |
Echinococcus multilocularis | BC026374 protein (S09 family) | 0.0018 | 0.0213 | 0.0213 |
Brugia malayi | Carboxylesterase family protein | 0.0018 | 0.0213 | 0.0331 |
Brugia malayi | Iron-sulfur cluster assembly accessory protein | 0.0047 | 0.1066 | 0.1658 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.12 | 0.1867 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0106 | 0.2776 | 1 |
Schistosoma mansoni | inositol monophosphatase | 0.0039 | 0.0818 | 0.2949 |
Echinococcus granulosus | acetylcholinesterase | 0.0106 | 0.2776 | 0.2776 |
Mycobacterium ulcerans | extragenic suppressor protein SuhB | 0.0039 | 0.0818 | 0.455 |
Echinococcus multilocularis | tumor protein p63 | 0.0355 | 1 | 1 |
Echinococcus granulosus | GPCR family 2 | 0.0015 | 0.0141 | 0.0141 |
Plasmodium falciparum | choline kinase | 0.0035 | 0.0708 | 0.5 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0033 | 0.0663 | 0.1031 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0064 | 0.1544 | 1 |
Schistosoma mansoni | cellular tumor antigen P53 | 0.0052 | 0.12 | 0.4325 |
Echinococcus granulosus | neuroligin | 0.0018 | 0.0213 | 0.0213 |
Echinococcus granulosus | BC026374 protein S09 family | 0.0018 | 0.0213 | 0.0213 |
Brugia malayi | Carboxylesterase family protein | 0.0018 | 0.0213 | 0.0331 |
Echinococcus multilocularis | family S9 non peptidase ue (S09 family) | 0.0018 | 0.0213 | 0.0213 |
Brugia malayi | Carboxylesterase family protein | 0.0018 | 0.0213 | 0.0331 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0018 | 0.0213 | 0.0767 |
Onchocerca volvulus | 0.0018 | 0.0213 | 0.1773 | |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0213 | 0.0331 |
Schistosoma mansoni | neuroligin 3 (S09 family) | 0.0018 | 0.0213 | 0.0767 |
Schistosoma mansoni | inositol monophosphatase | 0.0039 | 0.0818 | 0.2949 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0213 | 0.0331 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0015 | 0.0141 | 0.0141 |
Loa Loa (eye worm) | carboxylesterase | 0.0018 | 0.0213 | 0.0331 |
Onchocerca volvulus | 0.0052 | 0.12 | 1 | |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0039 | 0.0818 | 0.5 |
Echinococcus granulosus | survival motor neuron protein 1 | 0.0232 | 0.643 | 0.643 |
Onchocerca volvulus | 0.0018 | 0.0213 | 0.1773 | |
Echinococcus granulosus | choline:ethanolamine kinase | 0.0035 | 0.0708 | 0.0708 |
Mycobacterium leprae | possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). | 0.0035 | 0.07 | 0.5 |
Echinococcus multilocularis | tar DNA binding protein | 0.0066 | 0.1624 | 0.1624 |
Brugia malayi | hypothetical protein | 0.0018 | 0.0213 | 0.0331 |
Toxoplasma gondii | aldehyde dehydrogenase | 0.0064 | 0.1544 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0213 | 0.0331 |
Echinococcus multilocularis | aldehyde dehydrogenase, mitochondrial | 0.0064 | 0.1544 | 0.1544 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0064 | 0.1544 | 1 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0049 | 0.1112 | 0.173 |
Entamoeba histolytica | myo-inositol monophosphatase, putative | 0.0039 | 0.0818 | 0.5 |
Onchocerca volvulus | 0.0018 | 0.0213 | 0.1773 | |
Schistosoma mansoni | tar DNA-binding protein | 0.0066 | 0.1624 | 0.5851 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0015 | 0.0141 | 0.022 |
Echinococcus multilocularis | acetylcholinesterase | 0.0106 | 0.2776 | 0.2776 |
Trypanosoma brucei | inositol-1(or 4)-monophosphatase 1, putative | 0.0039 | 0.0818 | 0.5 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0018 | 0.0213 | 0.0767 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0015 | 0.0141 | 0.022 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0049 | 0.1112 | 0.173 |
Schistosoma mansoni | tar DNA-binding protein | 0.0066 | 0.1624 | 0.5851 |
Echinococcus granulosus | tar DNA binding protein | 0.0066 | 0.1624 | 0.1624 |
Schistosoma mansoni | hypothetical protein | 0.0015 | 0.0141 | 0.0509 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0066 | 0.1624 | 0.2526 |
Echinococcus multilocularis | choline:ethanolamine kinase | 0.0035 | 0.0708 | 0.0708 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0018 | 0.0213 | 0.0767 |
Onchocerca volvulus | 0.0018 | 0.0213 | 0.1773 | |
Echinococcus granulosus | family S9 non peptidase ue S09 family | 0.0018 | 0.0213 | 0.0213 |
Echinococcus multilocularis | acetylcholinesterase | 0.0106 | 0.2776 | 0.2776 |
Schistosoma mansoni | hypothetical protein | 0.0015 | 0.0141 | 0.0509 |
Echinococcus granulosus | carboxylesterase 5A | 0.0106 | 0.2776 | 0.2776 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0125 | 0.3334 | 0.5185 |
Brugia malayi | MH2 domain containing protein | 0.0125 | 0.3334 | 0.5185 |
Brugia malayi | hypothetical protein | 0.0232 | 0.643 | 1 |
Onchocerca volvulus | 0.0018 | 0.0213 | 0.1773 | |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0663 | 0.1031 |
Plasmodium vivax | choline kinase, putative | 0.0035 | 0.0708 | 0.5 |
Mycobacterium tuberculosis | Inositol-1-monophosphatase SuhB | 0.0035 | 0.07 | 0.3663 |
Schistosoma mansoni | acetylcholinesterase | 0.0018 | 0.0213 | 0.0767 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0039 | 0.0818 | 0.5 |
Brugia malayi | Carboxylesterase family protein | 0.0106 | 0.2776 | 0.4317 |
Brugia malayi | TAR-binding protein | 0.0066 | 0.1624 | 0.2526 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0213 | 0.0331 |
Wolbachia endosymbiont of Brugia malayi | fructose-1,6-bisphosphatase | 0.0039 | 0.0818 | 0.5 |
Echinococcus multilocularis | carboxylesterase 5A | 0.0106 | 0.2776 | 0.2776 |
Loa Loa (eye worm) | hypothetical protein | 0.0015 | 0.0141 | 0.022 |
Leishmania major | aldehyde dehydrogenase, mitochondrial precursor | 0.0064 | 0.1544 | 1 |
Echinococcus multilocularis | GPCR, family 2 | 0.0015 | 0.0141 | 0.0141 |
Echinococcus granulosus | inositol monophosphatase 1 | 0.0039 | 0.0818 | 0.0818 |
Schistosoma mansoni | tar DNA-binding protein | 0.0066 | 0.1624 | 0.5851 |
Brugia malayi | RNA binding protein | 0.0066 | 0.1624 | 0.2526 |
Schistosoma mansoni | hypothetical protein | 0.0033 | 0.0663 | 0.2388 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0213 | 0.0331 |
Loa Loa (eye worm) | hypothetical protein | 0.0232 | 0.643 | 1 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0064 | 0.1544 | 0.5563 |
Schistosoma mansoni | survival motor neuron protein | 0.0047 | 0.1066 | 0.3841 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0015 | 0.0141 | 0.0141 |
Schistosoma mansoni | hypothetical protein | 0.0047 | 0.1066 | 0.3841 |
Echinococcus granulosus | aldehyde dehydrogenase mitochondrial | 0.0064 | 0.1544 | 0.1544 |
Onchocerca volvulus | 0.0047 | 0.1066 | 0.8881 | |
Loa Loa (eye worm) | carboxylesterase | 0.0106 | 0.2776 | 0.4317 |
Brugia malayi | Inositol-1 | 0.0039 | 0.0818 | 0.1273 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0015 | 0.0141 | 0.0141 |
Schistosoma mansoni | hypothetical protein | 0.0015 | 0.0141 | 0.0509 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0015 | 0.0141 | 0.022 |
Loa Loa (eye worm) | hypothetical protein | 0.0106 | 0.2776 | 0.4317 |
Brugia malayi | Carboxylesterase family protein | 0.0106 | 0.2776 | 0.4317 |
Schistosoma mansoni | BC026374 protein (S09 family) | 0.0018 | 0.0213 | 0.0767 |
Loa Loa (eye worm) | RNA binding protein | 0.0066 | 0.1624 | 0.2526 |
Echinococcus multilocularis | survival motor neuron protein 1 | 0.0232 | 0.643 | 0.643 |
Loa Loa (eye worm) | hypothetical protein | 0.0106 | 0.2776 | 0.4317 |
Loa Loa (eye worm) | inositol-1 | 0.0039 | 0.0818 | 0.1273 |
Schistosoma mansoni | tar DNA-binding protein | 0.0066 | 0.1624 | 0.5851 |
Schistosoma mansoni | gliotactin | 0.0018 | 0.0213 | 0.0767 |
Brugia malayi | Choline/ethanolamine kinase family protein | 0.0035 | 0.0708 | 0.1101 |
Trichomonas vaginalis | inositol monophosphatase, putative | 0.0039 | 0.0818 | 1 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.0106 | 0.2776 | 0.4317 |
Loa Loa (eye worm) | carboxylesterase | 0.0018 | 0.0213 | 0.0331 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0066 | 0.1624 | 0.2526 |
Echinococcus multilocularis | inositol monophosphatase 1 | 0.0039 | 0.0818 | 0.0818 |
Echinococcus multilocularis | para nitrobenzyl esterase | 0.0018 | 0.0213 | 0.0213 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0049 | 0.1112 | 0.173 |
Toxoplasma gondii | inositol(myo)-1(or 4)-monophosphatase 2, putative | 0.0039 | 0.0818 | 0.1325 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.0039 | 0.0818 | 1 |
Mycobacterium tuberculosis | Probable aldehyde dehydrogenase | 0.0064 | 0.1544 | 1 |
Loa Loa (eye worm) | TAR-binding protein | 0.0066 | 0.1624 | 0.2526 |
Echinococcus multilocularis | neuroligin | 0.0018 | 0.0213 | 0.0213 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0064 | 0.1544 | 0.5563 |
Schistosoma mansoni | hypothetical protein | 0.0015 | 0.0141 | 0.0509 |
Loa Loa (eye worm) | choline/ethanolamine kinase | 0.0035 | 0.0708 | 0.1101 |
Echinococcus granulosus | acetylcholinesterase | 0.0106 | 0.2776 | 0.2776 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.1112 | 0.173 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.