Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | geranylgeranyl transferase type II beta subunit, putative | 0.0044 | 0.0899 | 0.0805 |
Loa Loa (eye worm) | oxidoreductase | 0.0024 | 0.0333 | 0.0318 |
Trypanosoma cruzi | cytochrome P450 reductase, putative | 0.0028 | 0.0444 | 0.3715 |
Treponema pallidum | sodium- and chloride- dependent transporter | 0.022 | 0.5968 | 1 |
Plasmodium vivax | aspartyl proteinase, putative | 0.0033 | 0.0578 | 0.0481 |
Echinococcus multilocularis | tyrosine protein kinase Abl | 0.0118 | 0.3018 | 0.4016 |
Mycobacterium ulcerans | 3-oxoacyl-ACP reductase | 0.0024 | 0.0333 | 0.0204 |
Plasmodium vivax | amine transporter, putative | 0.0037 | 0.0707 | 0.0611 |
Trypanosoma brucei | NADPH-cytochrome p450 reductase, putative | 0.0028 | 0.0444 | 0.3715 |
Mycobacterium tuberculosis | Possible oxidoreductase | 0.0024 | 0.0333 | 0.0204 |
Brugia malayi | hypothetical protein | 0.0037 | 0.0707 | 0.1184 |
Trypanosoma cruzi | beta-ketoacyl-ACP reductase | 0.0024 | 0.0333 | 0.2511 |
Toxoplasma gondii | hypothetical protein | 0.0016 | 0.0102 | 0.0068 |
Mycobacterium tuberculosis | Probable short-chain type dehydrogenase/reductase | 0.0024 | 0.0333 | 0.0204 |
Brugia malayi | Eukaryotic aspartyl protease family protein | 0.0018 | 0.0155 | 0.026 |
Brugia malayi | Variant SH3 domain containing protein | 0.0017 | 0.0112 | 0.0188 |
Schistosoma mansoni | cathepsin D (A01 family) | 0.007 | 0.1658 | 0.2292 |
Schistosoma mansoni | sodium/chloride dependent transporter | 0.022 | 0.5968 | 0.8375 |
Echinococcus multilocularis | tyrosine protein kinase Fyn | 0.0019 | 0.0181 | 0.0108 |
Loa Loa (eye worm) | Sodium:neurotransmitter symporter family protein | 0.0037 | 0.0707 | 0.0833 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0263 | 0.0222 |
Schistosoma mansoni | norepinephrine/norepinephrine transporter | 0.0037 | 0.0707 | 0.0949 |
Echinococcus multilocularis | sodium and chloride dependent glycine | 0.0037 | 0.0707 | 0.0833 |
Mycobacterium tuberculosis | Probable dehydrogenase/reductase | 0.0024 | 0.0333 | 0.0204 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0707 | 0.0833 |
Schistosoma mansoni | hypothetical protein | 0.0018 | 0.0136 | 0.0144 |
Brugia malayi | Bromodomain containing protein | 0.002 | 0.0198 | 0.0332 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0029 | 0.0457 | 0.0489 |
Giardia lamblia | Hypothetical protein | 0.0025 | 0.0351 | 0.3129 |
Loa Loa (eye worm) | TK/ABL protein kinase | 0.0268 | 0.7364 | 1 |
Trypanosoma brucei | beta-ketoacyl-ACP reductase | 0.0024 | 0.0333 | 0.2511 |
Trichomonas vaginalis | geranylgeranyl transferase type II beta subunit, putative | 0.0044 | 0.0899 | 0.0805 |
Onchocerca volvulus | 0.0037 | 0.0707 | 0.1031 | |
Loa Loa (eye worm) | solute carrier family 6 member 4 | 0.022 | 0.5968 | 0.8078 |
Echinococcus multilocularis | methionine synthase reductase | 0.0017 | 0.0133 | 0.0042 |
Plasmodium falciparum | plasmepsin II | 0.0033 | 0.0578 | 0.0481 |
Plasmodium vivax | flavodoxin domain containing protein | 0.0025 | 0.0351 | 0.0252 |
Echinococcus granulosus | NCK adaptor protein | 0.0017 | 0.0112 | 0.0014 |
Echinococcus granulosus | tyrosine protein kinase ABL1 | 0.0268 | 0.7364 | 1 |
Toxoplasma gondii | enoyl-acyl carrier reductase ENR | 0.036 | 1 | 1 |
Mycobacterium tuberculosis | Possible oxidoreductase | 0.0024 | 0.0333 | 0.0204 |
Mycobacterium ulcerans | 3-ketoacyl-ACP reductase | 0.0024 | 0.0333 | 0.0204 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0112 | 0.0014 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0024 | 0.0333 | 0.0204 |
Echinococcus multilocularis | NADPH dependent diflavin oxidoreductase 1 | 0.0028 | 0.0444 | 0.0471 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0052 | 0.1124 | 0.1407 |
Echinococcus granulosus | NADPH cytochrome P450 reductase | 0.0028 | 0.0444 | 0.0471 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0707 | 0.0833 |
Loa Loa (eye worm) | hypothetical protein | 0.022 | 0.5968 | 0.8078 |
Mycobacterium ulcerans | oxidoreductase | 0.0024 | 0.0333 | 0.0204 |
Loa Loa (eye worm) | retinol dehydrogenase 12 | 0.0024 | 0.0333 | 0.0318 |
Toxoplasma gondii | short chain dehydrogenase family protein, putative | 0.0024 | 0.0333 | 0.03 |
Plasmodium vivax | plasmepsin V, putative | 0.0018 | 0.0155 | 0.0054 |
Echinococcus multilocularis | NCK adaptor protein | 0.0017 | 0.0112 | 0.0014 |
Schistosoma mansoni | subfamily A1A unassigned peptidase (A01 family) | 0.0018 | 0.0155 | 0.0171 |
Schistosoma mansoni | subfamily A1A unassigned peptidase (A01 family) | 0.0018 | 0.0155 | 0.0171 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0024 | 0.0333 | 0.0204 |
Toxoplasma gondii | Sodium:neurotransmitter symporter family protein | 0.0037 | 0.0707 | 0.0675 |
Brugia malayi | Tyrosine-protein kinase abl-1 | 0.0118 | 0.3018 | 0.5057 |
Trichomonas vaginalis | geranylgeranyl transferase type I beta subunit, putative | 0.0044 | 0.0899 | 0.0805 |
Plasmodium vivax | hypothetical protein, conserved | 0.0037 | 0.0707 | 0.0611 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0052 | 0.1124 | 0.1538 |
Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0024 | 0.0333 | 0.0558 |
Brugia malayi | aspartic protease BmAsp-2, identical | 0.0018 | 0.0155 | 0.026 |
Onchocerca volvulus | 0.0018 | 0.0155 | 0.009 | |
Echinococcus granulosus | tyrosine protein kinase Fyn | 0.0019 | 0.0181 | 0.0108 |
Echinococcus multilocularis | protein farnesyltransferase subunit beta | 0.0044 | 0.0899 | 0.1097 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0024 | 0.0333 | 0.0204 |
Plasmodium falciparum | plasmepsin IX | 0.0018 | 0.0155 | 0.0054 |
Schistosoma mansoni | cathepsin D (A01 family) | 0.007 | 0.1658 | 0.2292 |
Schistosoma mansoni | dihydropteridine reductase | 0.0024 | 0.0333 | 0.0422 |
Schistosoma mansoni | norepinephrine/norepinephrine transporter | 0.022 | 0.5968 | 0.8375 |
Trypanosoma cruzi | protein farnesyltransferase, putative | 0.0044 | 0.0899 | 0.8661 |
Leishmania major | lanosterol synthase, putative | 0.0036 | 0.0678 | 0.7229 |
Schistosoma mansoni | proto-oncogene tyrosine-protein kinase src | 0.0019 | 0.0181 | 0.0207 |
Echinococcus granulosus | serotonin transporter | 0.022 | 0.5968 | 0.8078 |
Loa Loa (eye worm) | aspartic protease BmAsp-1 | 0.0018 | 0.0155 | 0.0073 |
Schistosoma mansoni | tyrosine kinase | 0.026 | 0.712 | 1 |
Schistosoma mansoni | sodium-dependent amino acid transporter | 0.0037 | 0.0707 | 0.0949 |
Brugia malayi | Tyrosine-protein kinase abl-1 | 0.0159 | 0.4214 | 0.7061 |
Mycobacterium tuberculosis | NADH-dependent enoyl-[acyl-carrier-protein] reductase InhA (NADH-dependent enoyl-ACP reductase) | 0.036 | 1 | 1 |
Echinococcus multilocularis | tyrosine protein kinase ABL1 | 0.0268 | 0.7364 | 1 |
Echinococcus granulosus | sodium and chloride dependent glycine | 0.0037 | 0.0707 | 0.0833 |
Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0024 | 0.0333 | 0.0558 |
Loa Loa (eye worm) | variant SH3 domain-containing protein | 0.0017 | 0.0112 | 0.0014 |
Trichomonas vaginalis | hypothetical protein | 0.036 | 1 | 1 |
Brugia malayi | hypothetical protein | 0.0052 | 0.1124 | 0.1883 |
Brugia malayi | Variant SH3 domain containing protein | 0.0017 | 0.0112 | 0.0188 |
Trypanosoma cruzi | lanosterol synthase, putative | 0.0048 | 0.1022 | 1 |
Echinococcus multilocularis | sodium dependent neurotransmitter transporter | 0.0037 | 0.0707 | 0.0833 |
Trypanosoma brucei | oxidoreductase-like protein | 0.0024 | 0.0333 | 0.2511 |
Echinococcus granulosus | methionine synthase reductase | 0.0017 | 0.0133 | 0.0042 |
Trypanosoma cruzi | p450 reductase, putative | 0.0028 | 0.0444 | 0.3715 |
Echinococcus granulosus | sodium:chloride dependent neurotransmitter | 0.0037 | 0.0707 | 0.0833 |
Schistosoma mansoni | sodium-dependent neurotransmitter transporter | 0.0037 | 0.0707 | 0.0949 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0018 | 0.0136 | 0.0228 |
Echinococcus multilocularis | sodium:chloride dependent neurotransmitter | 0.0037 | 0.0707 | 0.0833 |
Echinococcus granulosus | sodium and chloride dependent glycine | 0.0037 | 0.0707 | 0.0833 |
Schistosoma mansoni | sodium/chloride dependent neurotransmitter transporter | 0.0037 | 0.0707 | 0.0949 |
Schistosoma mansoni | tyrosine kinase | 0.0019 | 0.0181 | 0.0207 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0155 | 0.0073 |
Echinococcus multilocularis | tyrosine protein kinase Src64B | 0.0019 | 0.0181 | 0.0108 |
Brugia malayi | Sex muscle abnormal protein 5 | 0.0017 | 0.0112 | 0.0188 |
Loa Loa (eye worm) | hypothetical protein | 0.022 | 0.5968 | 0.8078 |
Plasmodium falciparum | 3-oxoacyl-[acyl-carrier-protein] reductase | 0.0024 | 0.0333 | 0.0233 |
Loa Loa (eye worm) | hypothetical protein | 0.022 | 0.5968 | 0.8078 |
Echinococcus multilocularis | tyrosine protein kinase lyn tyrosine protein kinase blk | 0.0019 | 0.0181 | 0.0108 |
Echinococcus granulosus | NADPH dependent diflavin oxidoreductase 1 | 0.0028 | 0.0444 | 0.0471 |
Schistosoma mansoni | sodium/chloride dependent neurotransmitter transporter | 0.0037 | 0.0707 | 0.0949 |
Schistosoma mansoni | tyrosine kinase | 0.0019 | 0.0181 | 0.0207 |
Schistosoma mansoni | NADPH flavin oxidoreductase | 0.0014 | 0.004 | 0.0009 |
Toxoplasma gondii | aspartyl proteinase (eimepsin), putative | 0.0033 | 0.0578 | 0.0546 |
Brugia malayi | FAD binding domain containing protein | 0.0017 | 0.0133 | 0.0222 |
Brugia malayi | Sodium:neurotransmitter symporter family protein | 0.0037 | 0.0707 | 0.1184 |
Plasmodium vivax | NADPH-cytochrome p450 reductase, putative | 0.0028 | 0.0444 | 0.0345 |
Plasmodium falciparum | plasmepsin VI | 0.0033 | 0.0578 | 0.0481 |
Schistosoma mansoni | tyrosine kinase | 0.0019 | 0.0181 | 0.0207 |
Schistosoma mansoni | growth factor receptor-bound protein | 0.0017 | 0.0112 | 0.011 |
Mycobacterium tuberculosis | Probable short-chain type dehydrogenase/reductase | 0.0024 | 0.0333 | 0.0204 |
Schistosoma mansoni | sodium-dependent neurotransmitter transporter | 0.0037 | 0.0707 | 0.0949 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0031 | 0.0516 | 0.057 |
Mycobacterium tuberculosis | Probable short-chain type dehydrogenase/reductase | 0.0024 | 0.0333 | 0.0204 |
Mycobacterium ulcerans | 20-beta-hydroxysteroid dehydrogenase FabG3 | 0.0024 | 0.0333 | 0.0204 |
Echinococcus granulosus | tyrosine protein kinase Lyn | 0.0019 | 0.0181 | 0.0108 |
Entamoeba histolytica | hypothetical protein | 0.0052 | 0.1124 | 1 |
Schistosoma mansoni | tyrosine kinase | 0.0019 | 0.0181 | 0.0207 |
Echinococcus granulosus | tyrosine protein kinase Src42A | 0.0019 | 0.0181 | 0.0108 |
Echinococcus multilocularis | Glutamate receptor, ionotropic kainate 3 | 0.0024 | 0.0328 | 0.0311 |
Mycobacterium ulcerans | 3-alpha-hydroxysteroid dehydrogenase | 0.0024 | 0.0333 | 0.0204 |
Plasmodium vivax | aspartyl proteinase, putative | 0.0018 | 0.0155 | 0.0054 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0029 | 0.0457 | 0.0489 |
Schistosoma mansoni | hypothetical protein | 0.0087 | 0.2142 | 0.2975 |
Plasmodium vivax | enoyl-acyl carrier protein reductase | 0.036 | 1 | 1 |
Plasmodium vivax | plasmepsin IV, putative | 0.0033 | 0.0578 | 0.0481 |
Plasmodium vivax | farnesyltransferase beta subunit, putative | 0.0044 | 0.0899 | 0.0805 |
Echinococcus granulosus | tyrosine protein kinase Btk29A | 0.0019 | 0.0181 | 0.0108 |
Echinococcus multilocularis | NADPH cytochrome P450 reductase | 0.0028 | 0.0444 | 0.0471 |
Schistosoma mansoni | subfamily A1A unassigned peptidase (A01 family) | 0.0018 | 0.0155 | 0.0171 |
Brugia malayi | aspartic protease BmAsp-1, identical | 0.0018 | 0.0155 | 0.026 |
Plasmodium falciparum | plasmepsin VII | 0.0018 | 0.0155 | 0.0054 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0024 | 0.0333 | 0.0204 |
Onchocerca volvulus | 0.0018 | 0.0155 | 0.009 | |
Plasmodium vivax | conserved Plasmodium protein, unknown function | 0.0032 | 0.0555 | 0.0457 |
Loa Loa (eye worm) | hypothetical protein | 0.0106 | 0.2682 | 0.3553 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0679 | 0.0795 |
Leishmania major | p450 reductase, putative | 0.0028 | 0.0444 | 0.4289 |
Chlamydia trachomatis | sulfite reductase | 0.0017 | 0.0133 | 0.0001 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0136 | 0.0047 |
Echinococcus granulosus | growth factor receptor bound protein 2 | 0.0017 | 0.0112 | 0.0014 |
Schistosoma mansoni | hypothetical protein | 0.0087 | 0.2142 | 0.2975 |
Brugia malayi | Protein prenyltransferase alpha subunit repeat containing protein | 0.0016 | 0.0102 | 0.0171 |
Echinococcus multilocularis | sodium and chloride dependent glycine | 0.0037 | 0.0707 | 0.0833 |
Mycobacterium tuberculosis | Possible 20-beta-hydroxysteroid dehydrogenase FabG3 (cortisone reductase) ((R)-20-hydroxysteroid dehydrogenase) | 0.0024 | 0.0333 | 0.0204 |
Plasmodium vivax | aspartyl protease, putative | 0.0018 | 0.0155 | 0.0054 |
Toxoplasma gondii | aspartyl protease ASP1 | 0.0033 | 0.0578 | 0.0546 |
Leishmania major | NADPH-cytochrome p450 reductase-like protein | 0.0028 | 0.0444 | 0.4289 |
Brugia malayi | FAD binding domain containing protein | 0.0028 | 0.0444 | 0.0744 |
Schistosoma mansoni | norepinephrine/norepinephrine transporter | 0.0037 | 0.0707 | 0.0949 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0155 | 0.0073 |
Schistosoma mansoni | sodium/chloride dependent transporter | 0.0037 | 0.0707 | 0.0949 |
Brugia malayi | hypothetical protein | 0.0018 | 0.0155 | 0.026 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0707 | 0.0833 |
Schistosoma mansoni | hypothetical protein | 0.0052 | 0.1124 | 0.1538 |
Echinococcus multilocularis | tyrosine protein kinase Fgr | 0.0019 | 0.0181 | 0.0108 |
Echinococcus granulosus | tyrosine protein kinase Fyn | 0.0019 | 0.0181 | 0.0108 |
Plasmodium falciparum | protein farnesyltransferase subunit beta | 0.0044 | 0.0899 | 0.0805 |
Schistosoma mansoni | sodium/chloride dependent neurotransmitter transporter | 0.0037 | 0.0707 | 0.0949 |
Plasmodium falciparum | transporter, putative | 0.0037 | 0.0707 | 0.0611 |
Leishmania major | cytochrome P450 reductase, putative | 0.0025 | 0.0351 | 0.3129 |
Brugia malayi | Pepsin A precursor | 0.0018 | 0.0155 | 0.026 |
Mycobacterium ulcerans | formate dehydrogenase H FdhF | 0.0028 | 0.0444 | 0.0316 |
Echinococcus granulosus | cathepsin d lysosomal aspartyl protease | 0.0033 | 0.0578 | 0.0656 |
Entamoeba histolytica | hypothetical protein | 0.0052 | 0.1124 | 1 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0024 | 0.0333 | 0.0204 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0024 | 0.0333 | 0.0204 |
Wolbachia endosymbiont of Brugia malayi | enoyl-ACP reductase | 0.036 | 1 | 1 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0024 | 0.0333 | 0.0204 |
Toxoplasma gondii | aspartyl protease | 0.0018 | 0.0155 | 0.0121 |
Brugia malayi | flavodoxin family protein | 0.0028 | 0.0444 | 0.0744 |
Toxoplasma gondii | eukaryotic aspartyl protease superfamily protein | 0.0018 | 0.0155 | 0.0121 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0024 | 0.0333 | 0.0204 |
Schistosoma mansoni | subfamily A1A unassigned peptidase (A01 family) | 0.0018 | 0.0155 | 0.0171 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0024 | 0.0333 | 0.0204 |
Echinococcus multilocularis | nmda type glutamate receptor | 0.0024 | 0.0328 | 0.0311 |
Mycobacterium ulcerans | 3-oxoacyl-ACP reductase | 0.0024 | 0.0333 | 0.0204 |
Echinococcus multilocularis | tyrosine protein kinase Fyn | 0.0019 | 0.0181 | 0.0108 |
Onchocerca volvulus | 0.022 | 0.5968 | 1 | |
Schistosoma mansoni | 5-methyl tetrahydrofolate-homocysteine methyltransferase reductase | 0.0017 | 0.0133 | 0.0139 |
Toxoplasma gondii | Sodium:neurotransmitter symporter family protein | 0.0037 | 0.0707 | 0.0675 |
Trypanosoma brucei | protein farnesyltransferase beta subunit | 0.0044 | 0.0899 | 0.8661 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0029 | 0.0457 | 0.0597 |
Echinococcus multilocularis | tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase | 0.0019 | 0.0181 | 0.0108 |
Trichomonas vaginalis | Clan AA, family A1, cathepsin D-like aspartic peptidase | 0.0033 | 0.0578 | 0.0481 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0024 | 0.0333 | 0.0204 |
Mycobacterium ulcerans | 3-ketoacyl-ACP reductase | 0.0024 | 0.0333 | 0.0204 |
Onchocerca volvulus | 0.0037 | 0.0707 | 0.1031 | |
Loa Loa (eye worm) | SRC-1 | 0.0019 | 0.0181 | 0.0108 |
Toxoplasma gondii | Sodium:neurotransmitter symporter family protein | 0.0037 | 0.0707 | 0.0675 |
Schistosoma mansoni | growth factor receptor-bound protein | 0.0017 | 0.0112 | 0.011 |
Brugia malayi | Protein prenyltransferase alpha subunit repeat containing protein | 0.0016 | 0.0102 | 0.0171 |
Plasmodium falciparum | nitric oxide synthase, putative | 0.0028 | 0.0444 | 0.0345 |
Trypanosoma cruzi | cytochrome P450 reductase, putative | 0.0028 | 0.0444 | 0.3715 |
Plasmodium falciparum | plasmepsin X | 0.0018 | 0.0155 | 0.0054 |
Trichomonas vaginalis | geranylgeranyl transferase type II beta subunit, putative | 0.0044 | 0.0899 | 0.0805 |
Toxoplasma gondii | 3-ketoacyl-(acyl-carrier-protein) reductase | 0.0024 | 0.0333 | 0.03 |
Echinococcus multilocularis | c src tyrosine kinase | 0.0019 | 0.0181 | 0.0108 |
Plasmodium falciparum | plasmepsin V | 0.0018 | 0.0155 | 0.0054 |
Entamoeba histolytica | protein farnesyltransferase beta subunit, putative | 0.0044 | 0.0899 | 0.7798 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0024 | 0.0333 | 0.0204 |
Echinococcus granulosus | 3 oxoacyl acyl carrier protein reductase | 0.0024 | 0.0333 | 0.0318 |
Echinococcus multilocularis | tyrosine protein kinase Fyn | 0.0019 | 0.0181 | 0.0108 |
Schistosoma mansoni | proto-oncogene tyrosine-protein kinase abl1 | 0.0017 | 0.0112 | 0.011 |
Brugia malayi | SRC-1 | 0.0019 | 0.0181 | 0.0303 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0707 | 0.0833 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0024 | 0.0333 | 0.0204 |
Brugia malayi | Sodium:neurotransmitter symporter family protein | 0.0037 | 0.0707 | 0.1184 |
Echinococcus multilocularis | cathepsin d (lysosomal aspartyl protease) | 0.0033 | 0.0578 | 0.0656 |
Mycobacterium leprae | NADH-DEPENDENT ENOYL-[ACYL-CARRIER-PROTEIN] REDUCTASE INHA (NADH-DEPENDENT ENOYL-ACP REDUCTASE) | 0.036 | 1 | 1 |
Mycobacterium ulcerans | enoyl-(acyl carrier protein) reductase | 0.036 | 1 | 1 |
Schistosoma mansoni | rab geranylgeranyl transferase alpha subunit | 0.0016 | 0.0102 | 0.0096 |
Trypanosoma brucei | pteridine reductase 1 | 0.0024 | 0.0333 | 0.2511 |
Schistosoma mansoni | sodium/chloride dependent transporter | 0.0037 | 0.0707 | 0.0949 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0029 | 0.0457 | 0.0766 |
Plasmodium falciparum | plasmepsin IV | 0.0033 | 0.0578 | 0.0481 |
Leishmania major | pteridine reductase 1 | 0.0024 | 0.0333 | 0.2899 |
Loa Loa (eye worm) | FAD binding domain-containing protein | 0.0028 | 0.0444 | 0.0471 |
Leishmania major | 3-oxoacyl-ACP reductase, putative | 0.0024 | 0.0333 | 0.2899 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0235 | 0.0183 |
Entamoeba histolytica | hypothetical protein | 0.0052 | 0.1124 | 1 |
Trypanosoma brucei | NADPH-dependent diflavin oxidoreductase 1 | 0.0028 | 0.0444 | 0.3715 |
Onchocerca volvulus | 0.0024 | 0.0333 | 0.0394 | |
Echinococcus multilocularis | serotonin transporter | 0.022 | 0.5968 | 0.8078 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0026 | 0.037 | 0.0619 |
Loa Loa (eye worm) | prenyltransferase and squalene oxidase repeat family protein | 0.0044 | 0.0899 | 0.1097 |
Chlamydia trachomatis | Ssodium-dependent amino acid transporter | 0.0037 | 0.0707 | 0.0582 |
Giardia lamblia | Nitric oxide synthase, inducible | 0.0025 | 0.0351 | 0.3129 |
Schistosoma mansoni | protein farnesyltransferase subunit beta | 0.0044 | 0.0899 | 0.122 |
Schistosoma mansoni | adapter molecule crk | 0.0017 | 0.0112 | 0.011 |
Schistosoma mansoni | cytochrome P450 reductase | 0.0028 | 0.0444 | 0.0578 |
Trypanosoma cruzi | NADPH-dependent FMN/FAD containing oxidoreductase, putative | 0.0028 | 0.0444 | 0.3715 |
Trypanosoma cruzi | oxidoreductase-like protein, putative | 0.0024 | 0.0333 | 0.2511 |
Schistosoma mansoni | amine GPCR | 0.0178 | 0.4764 | 0.6676 |
Echinococcus granulosus | nmda type glutamate receptor | 0.0024 | 0.0328 | 0.0311 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0029 | 0.0457 | 0.0489 |
Schistosoma mansoni | 3-oxoacyl-[ACP] reductase | 0.0024 | 0.0333 | 0.0422 |
Echinococcus multilocularis | uncharacterized sodium dependent transporter | 0.0037 | 0.0707 | 0.0833 |
Brugia malayi | Sodium:neurotransmitter symporter family protein | 0.0037 | 0.0707 | 0.1184 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0029 | 0.0457 | 0.0489 |
Giardia lamblia | Prenyltransferase | 0.0044 | 0.0899 | 1 |
Onchocerca volvulus | 0.0106 | 0.2682 | 0.4398 | |
Echinococcus multilocularis | proto oncogene tyrosine protein kinase LCK | 0.0019 | 0.0181 | 0.0108 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0199 | 0.0134 |
Echinococcus granulosus | protein farnesyltransferase subunit beta | 0.0044 | 0.0899 | 0.1097 |
Echinococcus granulosus | c src tyrosine kinase | 0.0019 | 0.0181 | 0.0108 |
Echinococcus granulosus | proto oncogene tyrosine protein kinase LCK | 0.0019 | 0.0181 | 0.0108 |
Echinococcus granulosus | geminin | 0.0087 | 0.2142 | 0.281 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0444 | 0.0471 |
Trypanosoma brucei | lanosterol synthase | 0.0048 | 0.1022 | 1 |
Plasmodium falciparum | plasmepsin III | 0.0018 | 0.0155 | 0.0054 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0024 | 0.0333 | 0.0204 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0031 | 0.0516 | 0.057 |
Echinococcus granulosus | uncharacterized sodium dependent transporter | 0.0037 | 0.0707 | 0.0833 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.037 | 0.0369 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.0333 | 0.0318 |
Echinococcus granulosus | sodium dependent neurotransmitter transporter | 0.0037 | 0.0707 | 0.0833 |
Toxoplasma gondii | hypothetical protein | 0.0037 | 0.0707 | 0.0675 |
Leishmania major | oxidoreductase-like protein | 0.0024 | 0.0333 | 0.2899 |
Schistosoma mansoni | subfamily A1A unassigned peptidase (A01 family) | 0.0018 | 0.0155 | 0.0171 |
Trichomonas vaginalis | type I geranylgeranyltransferase beta subunit, putative | 0.0044 | 0.0899 | 0.0805 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0026 | 0.037 | 0.0369 |
Trypanosoma cruzi | protein farnesyltransferase, putative | 0.0044 | 0.0899 | 0.8661 |
Plasmodium falciparum | enoyl-acyl carrier reductase | 0.036 | 1 | 1 |
Schistosoma mansoni | bromodomain containing protein | 0.0033 | 0.0569 | 0.0754 |
Chlamydia trachomatis | oxoacy-ACP reductase | 0.0024 | 0.0333 | 0.0204 |
Brugia malayi | Bromodomain containing protein | 0.0039 | 0.0742 | 0.1244 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0029 | 0.0457 | 0.0597 |
Echinococcus multilocularis | geminin | 0.0087 | 0.2142 | 0.281 |
Entamoeba histolytica | hypothetical protein | 0.0052 | 0.1124 | 1 |
Plasmodium vivax | 3-oxoacyl-[acyl-carrier-protein] reductase, putative | 0.0024 | 0.0333 | 0.0233 |
Schistosoma mansoni | subfamily A1A unassigned peptidase (A01 family) | 0.0033 | 0.0578 | 0.0768 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0707 | 0.0833 |
Toxoplasma gondii | hypothetical protein | 0.0037 | 0.0707 | 0.0675 |
Brugia malayi | hypothetical protein | 0.0106 | 0.2682 | 0.4493 |
Plasmodium vivax | aspartyl protease, putative | 0.0018 | 0.0155 | 0.0054 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0024 | 0.0333 | 0.0204 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0018 | 0.0163 | 0.0084 |
Brugia malayi | hypothetical protein | 0.0018 | 0.0155 | 0.026 |
Plasmodium falciparum | plasmepsin VIII, putative | 0.0018 | 0.0155 | 0.0054 |
Loa Loa (eye worm) | Sodium:neurotransmitter symporter family protein | 0.0037 | 0.0707 | 0.0833 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0024 | 0.0333 | 0.0204 |
Mycobacterium tuberculosis | Probable 3-oxoacyl-[acyl-carrier protein] reductase FabG2 (3-ketoacyl-acyl carrier protein reductase) | 0.0024 | 0.0333 | 0.0204 |
Leishmania major | farnesyltransferase beta subunit | 0.0044 | 0.0899 | 1 |
Schistosoma mansoni | subfamily A1A unassigned peptidase (A01 family) | 0.0018 | 0.0155 | 0.0171 |
Mycobacterium ulcerans | 3-ketoacyl-ACP reductase | 0.0024 | 0.0333 | 0.0204 |
Echinococcus granulosus | 3'partial|tyrosine protein kinase Fgr | 0.0019 | 0.0181 | 0.0108 |
Onchocerca volvulus | 0.0024 | 0.0333 | 0.0394 | |
Trypanosoma brucei | NADPH--cytochrome P450 reductase, putative | 0.0028 | 0.0444 | 0.3715 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0024 | 0.0333 | 0.0204 |
Trichomonas vaginalis | sulfite reductase, putative | 0.0028 | 0.0444 | 0.0345 |
Brugia malayi | Sodium:neurotransmitter symporter family protein 1, putative | 0.0037 | 0.0707 | 0.1184 |
Loa Loa (eye worm) | 3-hydroxyacyl-CoA dehydrogenase type II | 0.0024 | 0.0333 | 0.0318 |
Loa Loa (eye worm) | sex muscle abnormal protein 5 | 0.0017 | 0.0112 | 0.0014 |
Entamoeba histolytica | 3-oxoacyl-(acyl-carrier protein) reductase, putative | 0.0024 | 0.0333 | 0.2261 |
Trypanosoma cruzi | lanosterol synthase, putative | 0.0048 | 0.1022 | 1 |
Trypanosoma brucei | NADPH--cytochrome P450 reductase, putative | 0.0028 | 0.0444 | 0.3715 |
Trypanosoma cruzi | beta-ketoacyl-ACP reductase | 0.0024 | 0.0333 | 0.2511 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0029 | 0.0457 | 0.0489 |
Loa Loa (eye worm) | hypothetical protein | 0.0101 | 0.2537 | 0.3353 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0024 | 0.0333 | 0.0204 |
Schistosoma mansoni | nck2/grb4 | 0.0017 | 0.0112 | 0.011 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0024 | 0.0333 | 0.0204 |
Plasmodium vivax | aspartyl protease, putative | 0.0018 | 0.0155 | 0.0054 |
Loa Loa (eye worm) | serotonin transporter b | 0.022 | 0.5968 | 0.8078 |
Schistosoma mansoni | subfamily A1A unassigned peptidase (A01 family) | 0.0018 | 0.0155 | 0.0171 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0029 | 0.0457 | 0.0597 |
Mycobacterium tuberculosis | Halimadienyl diphosphate synthase | 0.0048 | 0.1022 | 0.0902 |
Echinococcus multilocularis | growth factor receptor bound protein 2 | 0.0017 | 0.0112 | 0.0014 |
Brugia malayi | Prenyltransferase and squalene oxidase repeat family protein | 0.0044 | 0.0899 | 0.1506 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0024 | 0.0333 | 0.0204 |
Brugia malayi | Sodium:neurotransmitter symporter family protein | 0.022 | 0.5968 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0707 | 0.0833 |
Leishmania major | dehydrogenase/oxidoreductase-like protein | 0.0024 | 0.0333 | 0.2899 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0024 | 0.0333 | 0.0204 |
Echinococcus granulosus | tyrosine protein kinase Src64B | 0.0019 | 0.0181 | 0.0108 |
Toxoplasma gondii | 2,4-dienoyl CoA reductase 2, peroxisomal family protein | 0.0024 | 0.0333 | 0.03 |
Loa Loa (eye worm) | norepinephrine transporter | 0.022 | 0.5968 | 0.8078 |
Echinococcus multilocularis | 3 oxoacyl acyl carrier protein reductase | 0.0024 | 0.0333 | 0.0318 |
Toxoplasma gondii | prenyltransferase and squalene oxidase repeat-containing protein | 0.0044 | 0.0899 | 0.0868 |
Echinococcus granulosus | uncharacterized sodium dependent transporter | 0.0037 | 0.0707 | 0.0833 |
Loa Loa (eye worm) | aspartic protease BmAsp-2 | 0.0033 | 0.0578 | 0.0656 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0024 | 0.0333 | 0.0204 |
Plasmodium falciparum | amino acid transporter, putative | 0.0037 | 0.0707 | 0.0611 |
Plasmodium falciparum | plasmepsin I | 0.0033 | 0.0578 | 0.0481 |
Loa Loa (eye worm) | FAD binding domain-containing protein | 0.0017 | 0.0133 | 0.0042 |
Mycobacterium ulcerans | 3-ketoacyl-ACP reductase | 0.0024 | 0.0333 | 0.0204 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0578 | 0.0656 |
Toxoplasma gondii | aspartyl protease ASP3 | 0.0018 | 0.0155 | 0.0121 |
Schistosoma mansoni | memapsin-2 (A01 family) | 0.0181 | 0.4853 | 0.6801 |
Echinococcus multilocularis | tyrosine protein kinase Btk29A | 0.0019 | 0.0181 | 0.0108 |
Echinococcus granulosus | tyrosine protein kinase Fyn | 0.0019 | 0.0181 | 0.0108 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0052 | 0.1124 | 0.1407 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0707 | 0.0833 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0018 | 0.0163 | 0.0084 |
Schistosoma mansoni | protein farnesyltransferase alpha subunit | 0.0016 | 0.0102 | 0.0096 |
Trichomonas vaginalis | NADPH fad oxidoreductase, putative | 0.0025 | 0.0351 | 0.0252 |
Loa Loa (eye worm) | aspartyl protease 6 | 0.0018 | 0.0155 | 0.0073 |
Schistosoma mansoni | subfamily A1A unassigned peptidase (A01 family) | 0.0018 | 0.0155 | 0.0171 |
Echinococcus multilocularis | tyrosine protein kinase Src42A | 0.0019 | 0.0181 | 0.0108 |
Mycobacterium ulcerans | 3-ketoacyl-ACP reductase | 0.0024 | 0.0333 | 0.0204 |
Leishmania major | dehydrogenase/oxidoreductase-like protein | 0.0024 | 0.0333 | 0.2899 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0026 | 0.037 | 0.0619 |
Onchocerca volvulus | 0.0037 | 0.0707 | 0.1031 | |
Trichomonas vaginalis | geranylgeranyl transferase type beta subunit, putative | 0.0044 | 0.0899 | 0.0805 |
Schistosoma mansoni | sodium-dependent neurotransmitter transporter | 0.0037 | 0.0707 | 0.0949 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.