Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Mycobacterium leprae | PROBABLE METHIONINE AMINOPEPTIDASE MAPB (MAP) (PEPTIDASE M) | 0.0028 | 0.5488 | 0.5 |
Mycobacterium ulcerans | methionine aminopeptidase | 0.0028 | 0.5488 | 0.5 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.0008 | 0 | 0.5 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.0008 | 0 | 0.5 |
Mycobacterium leprae | PROBABLE METHIONINE AMINOPEPTIDASE MAPA (MAP) (PEPTIDASE M) (MetAP) | 0.0028 | 0.5488 | 0.5 |
Mycobacterium tuberculosis | Methionine aminopeptidase MapA (map) (peptidase M) (MetAP) | 0.0028 | 0.5488 | 0.5 |
Toxoplasma gondii | methionine aminopeptidase | 0.0028 | 0.5488 | 0.422 |
Schistosoma mansoni | methionyl aminopeptidase 1 (M24 family) | 0.0028 | 0.5488 | 1 |
Wolbachia endosymbiont of Brugia malayi | methionine aminopeptidase | 0.0028 | 0.5488 | 0.5 |
Mycobacterium ulcerans | methionine aminopeptidase MapB | 0.0028 | 0.5488 | 0.5 |
Onchocerca volvulus | 0.0008 | 0 | 0.5 | |
Plasmodium vivax | methionine aminopeptidase 1a, putative | 0.0028 | 0.5488 | 0.422 |
Mycobacterium tuberculosis | Methionine aminopeptidase MapB (map) (peptidase M) | 0.0028 | 0.5488 | 0.5 |
Plasmodium falciparum | methionine aminopeptidase 1b, putative | 0.0044 | 1 | 1 |
Treponema pallidum | methionine aminopeptidase (map) | 0.0028 | 0.5488 | 0.5 |
Toxoplasma gondii | methionine aminopeptidase, type i, putative | 0.0028 | 0.5488 | 0.422 |
Chlamydia trachomatis | methionine aminopeptidase | 0.0028 | 0.5488 | 0.5 |
Leishmania major | methionine aminopeptidase, putative,metallo-peptidase, Clan MG, Family M24 | 0.0044 | 1 | 1 |
Echinococcus multilocularis | methionyl aminopeptidase 1 (M24 family) | 0.0028 | 0.5488 | 0.5488 |
Onchocerca volvulus | Bile acid receptor homolog | 0.0008 | 0 | 0.5 |
Trypanosoma brucei | methionine aminopeptidase, putative | 0.0044 | 1 | 1 |
Plasmodium vivax | methionine aminopeptidase 1b, putative | 0.0044 | 1 | 1 |
Schistosoma mansoni | methionyl aminopeptidase 1 (M24 family) | 0.0028 | 0.5488 | 1 |
Trypanosoma brucei | metallo- peptidase, Clan MG, Family M24 | 0.0044 | 1 | 1 |
Plasmodium falciparum | methionine aminopeptidase 1a, putative | 0.0028 | 0.5488 | 0.422 |
Loa Loa (eye worm) | methionine aminopeptidase type I | 0.0044 | 1 | 1 |
Echinococcus granulosus | methionyl aminopeptidase 1 M24 family | 0.0044 | 1 | 1 |
Echinococcus multilocularis | methionyl aminopeptidase 1 (M24 family) | 0.0044 | 1 | 1 |
Toxoplasma gondii | methionine aminopeptidase | 0.0044 | 1 | 1 |
Trypanosoma cruzi | metallo- peptidase, Clan MG, Family M24 | 0.0044 | 1 | 1 |
Trypanosoma brucei | methionine aminopeptidase, type I, putative | 0.0044 | 1 | 1 |
Trypanosoma cruzi | metallo- peptidase, Clan MG, Family M24 | 0.0044 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.