Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.0098 | 0.9232 | 0.9232 |
Brugia malayi | TAR-binding protein | 0.0066 | 0.4734 | 0.4734 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0103 | 0.9927 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0036 | 0.0469 | 0.0875 |
Brugia malayi | hypothetical protein | 0.0081 | 0.6752 | 0.6752 |
Loa Loa (eye worm) | hypothetical protein | 0.0071 | 0.5368 | 0.5368 |
Loa Loa (eye worm) | RNA binding protein | 0.0066 | 0.4734 | 0.4734 |
Leishmania major | hypothetical protein, conserved | 0.0081 | 0.6752 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0066 | 0.4734 | 0.8819 |
Schistosoma mansoni | hypothetical protein | 0.0071 | 0.5368 | 1 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0081 | 0.6752 | 1 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0081 | 0.6752 | 1 |
Brugia malayi | hypothetical protein | 0.0052 | 0.2714 | 0.2714 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0071 | 0.5368 | 0.5368 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0081 | 0.6752 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0081 | 0.6752 | 0.6752 |
Loa Loa (eye worm) | hypothetical protein | 0.0104 | 1 | 1 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0066 | 0.4734 | 0.4734 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0104 | 1 | 1 |
Brugia malayi | RNA binding protein | 0.0066 | 0.4734 | 0.4734 |
Echinococcus multilocularis | tar DNA binding protein | 0.0066 | 0.4734 | 0.4769 |
Schistosoma mansoni | tar DNA-binding protein | 0.0066 | 0.4734 | 0.8819 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0103 | 0.9927 | 1 |
Mycobacterium tuberculosis | Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) | 0.0033 | 0 | 0.5 |
Echinococcus multilocularis | Ataxin 2, N terminal,domain containing protein | 0.0036 | 0.0469 | 0.0473 |
Echinococcus granulosus | tar DNA binding protein | 0.0066 | 0.4734 | 0.4769 |
Schistosoma mansoni | tar DNA-binding protein | 0.0066 | 0.4734 | 0.8819 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0081 | 0.6752 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0066 | 0.4734 | 0.8819 |
Loa Loa (eye worm) | nuclear hormone receptor | 0.0098 | 0.9149 | 0.9149 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0081 | 0.6752 | 1 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0081 | 0.6752 | 1 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0081 | 0.6752 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0066 | 0.4734 | 0.8819 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0103 | 0.9927 | 0.9927 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0104 | 1 | 1 |
Loa Loa (eye worm) | TAR-binding protein | 0.0066 | 0.4734 | 0.4734 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0066 | 0.4734 | 0.4734 |
Echinococcus granulosus | Ataxin 2 N terminaldomain containing protein | 0.0036 | 0.0469 | 0.0473 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.