Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0036 | 0.1193 | 0.9937 |
Trichomonas vaginalis | neutral alpha-glucosidase ab precursor, putative | 0.0036 | 0.12 | 1 |
Toxoplasma gondii | ATP-dependent DNA helicase, RecQ family protein | 0.001 | 0.00000000020105 | 0.000000001676 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0036 | 0.12 | 1 |
Onchocerca volvulus | 0.0094 | 0.3836 | 1 | |
Entamoeba histolytica | glycosyl hydrolase, family 31 protein | 0.0036 | 0.12 | 1 |
Mycobacterium ulcerans | hypothetical protein | 0.0036 | 0.1193 | 0.5 |
Toxoplasma gondii | peptidylprolyl isomerase | 0.0033 | 0.1084 | 0.9035 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0036 | 0.12 | 1 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0036 | 0.1193 | 0.1645 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0036 | 0.12 | 1 |
Mycobacterium ulcerans | fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE | 0.0036 | 0.1193 | 0.5 |
Plasmodium vivax | hypothetical protein, conserved | 0.0036 | 0.1193 | 1 |
Leishmania major | glycosyl hydrolase-like protein | 0.0013 | 0.017 | 0.1168 |
Trypanosoma cruzi | peptidyl-prolyl cis-trans isomerase | 0.0033 | 0.1084 | 0.9007 |
Brugia malayi | beta-lactamase family protein | 0.0036 | 0.1193 | 0.1715 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0045 | 0.1635 | 0.2255 |
Schistosoma mansoni | rotamase | 0.0034 | 0.1121 | 0.1546 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0036 | 0.12 | 1 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0036 | 0.1193 | 0.9937 |
Brugia malayi | Bloom's syndrome protein homolog | 0.0023 | 0.0628 | 0.0903 |
Trypanosoma cruzi | ATP-dependent DEAD/H DNA helicase recQ, putative | 0.0013 | 0.013 | 0.0826 |
Schistosoma mansoni | alpha glucosidase | 0.0036 | 0.12 | 0.1655 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.1193 | 0.1715 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0036 | 0.1193 | 0.9937 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0013 | 0.017 | 0.0373 |
Leishmania major | alpha glucosidase II subunit, putative | 0.0036 | 0.12 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0045 | 0.1635 | 0.2255 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0036 | 0.12 | 1 |
Loa Loa (eye worm) | glycosyl hydrolase family 31 protein | 0.0036 | 0.12 | 0.1725 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0036 | 0.12 | 1 |
Onchocerca volvulus | 0.0036 | 0.1193 | 0.2791 | |
Entamoeba histolytica | glycosyl hydrolase, family 31 protein | 0.0036 | 0.12 | 1 |
Plasmodium falciparum | ADP-dependent DNA helicase RecQ | 0.0021 | 0.0498 | 1 |
Onchocerca volvulus | 0.0036 | 0.1193 | 0.2791 | |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0036 | 0.1193 | 0.9942 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0036 | 0.1193 | 0.1645 |
Echinococcus multilocularis | expressed protein | 0.0034 | 0.1121 | 0.1546 |
Schistosoma mansoni | hypothetical protein | 0.0169 | 0.725 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0034 | 0.1121 | 0.9262 |
Echinococcus multilocularis | neutral alpha glucosidase AB | 0.0036 | 0.12 | 0.1655 |
Loa Loa (eye worm) | RecQ helicase | 0.0023 | 0.0628 | 0.0903 |
Schistosoma mansoni | alpha-glucosidase | 0.0139 | 0.5924 | 0.8171 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0036 | 0.1193 | 0.9937 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0045 | 0.1635 | 0.2351 |
Brugia malayi | Glycosyl hydrolases family 31 protein | 0.0036 | 0.12 | 0.1725 |
Toxoplasma gondii | PPIC-type PPIASE domain-containing protein | 0.001 | 0.0034 | 0.0279 |
Trichomonas vaginalis | maltase-glucoamylase, putative | 0.0013 | 0.017 | 0.0373 |
Loa Loa (eye worm) | hypothetical protein | 0.0118 | 0.4942 | 0.7106 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0045 | 0.1635 | 0.2351 |
Brugia malayi | beta-lactamase family protein | 0.0036 | 0.1193 | 0.1715 |
Mycobacterium leprae | conserved hypothetical protein | 0.0036 | 0.1193 | 0.5 |
Wolbachia endosymbiont of Brugia malayi | parvulin-like peptidyl-prolyl isomerase, PPID | 0.001 | 0.0034 | 0.5 |
Onchocerca volvulus | 0.0036 | 0.1193 | 0.2791 | |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0036 | 0.1193 | 0.9942 |
Loa Loa (eye worm) | beta-lactamase | 0.0036 | 0.1193 | 0.1715 |
Entamoeba histolytica | glycosyl hydrolase, family 31 protein | 0.0013 | 0.017 | 0.0373 |
Trichomonas vaginalis | DNA helicase recq, putative | 0.0023 | 0.0628 | 0.4656 |
Echinococcus granulosus | geminin | 0.0169 | 0.725 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.1193 | 0.1715 |
Mycobacterium ulcerans | esterase/lipase LipP | 0.0036 | 0.1193 | 0.5 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0013 | 0.017 | 0.0373 |
Mycobacterium ulcerans | beta-lactamase | 0.0036 | 0.1193 | 0.5 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0013 | 0.017 | 0.0373 |
Trichomonas vaginalis | esterase, putative | 0.0036 | 0.1193 | 0.9937 |
Loa Loa (eye worm) | Pin1-type peptidyl-prolyl cis-trans isomerase | 0.0034 | 0.1121 | 0.1611 |
Loa Loa (eye worm) | glycosyl hydrolase family 31 protein | 0.0162 | 0.6954 | 1 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0036 | 0.1193 | 0.1715 |
Trypanosoma brucei | peptidyl-prolyl cis-trans isomerase/rotamase, putative | 0.0033 | 0.1084 | 0.9007 |
Echinococcus granulosus | expressed protein | 0.0034 | 0.1121 | 0.1546 |
Trypanosoma brucei | ATP-dependent DEAD/H DNA helicase recQ, putative | 0.0013 | 0.013 | 0.0826 |
Trichomonas vaginalis | rotamase, putative | 0.0033 | 0.1084 | 0.8918 |
Trypanosoma cruzi | glycosyl hydrolase-like protein, putative | 0.0013 | 0.017 | 0.1168 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0013 | 0.017 | 0.0373 |
Schistosoma mansoni | blooms syndrome DNA helicase | 0.0018 | 0.0403 | 0.0556 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0036 | 0.1193 | 0.1645 |
Echinococcus multilocularis | bloom syndrome protein | 0.0023 | 0.0628 | 0.0866 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0036 | 0.1193 | 0.9937 |
Trichomonas vaginalis | sucrase-isomaltase, putative | 0.0036 | 0.12 | 1 |
Mycobacterium leprae | Probable lipase LipE | 0.0036 | 0.1193 | 0.5 |
Toxoplasma gondii | ATP-dependent DNA helicase, RecQ family protein | 0.0016 | 0.0273 | 0.2276 |
Trichomonas vaginalis | maltase-glucoamylase, putative | 0.0036 | 0.12 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0013 | 0.017 | 0.0244 |
Trypanosoma cruzi | glycosyl hydrolase-like protein, putative | 0.0013 | 0.017 | 0.1168 |
Mycobacterium ulcerans | lipase LipD | 0.0036 | 0.1193 | 0.5 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0045 | 0.1635 | 0.2255 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.1193 | 0.1715 |
Schistosoma mansoni | hypothetical protein | 0.0169 | 0.725 | 1 |
Brugia malayi | Pin1-type peptidyl-prolyl cis-trans isomerase, BmPin1 | 0.0034 | 0.1121 | 0.1611 |
Trypanosoma brucei | glucosidase, putative | 0.0036 | 0.12 | 1 |
Brugia malayi | beta-lactamase | 0.0036 | 0.1193 | 0.1715 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0045 | 0.1635 | 0.2255 |
Trichomonas vaginalis | neutral alpha-glucosidase ab precursor, putative | 0.0013 | 0.017 | 0.0373 |
Toxoplasma gondii | glycosyl hydrolase, family 31 protein | 0.0036 | 0.12 | 1 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0045 | 0.1635 | 0.2255 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0045 | 0.1635 | 0.2255 |
Toxoplasma gondii | ABC1 family protein | 0.0036 | 0.1193 | 0.9944 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0036 | 0.12 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.1193 | 0.1715 |
Schistosoma mansoni | alpha-glucosidase | 0.0139 | 0.5924 | 0.8171 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.1193 | 0.1715 |
Echinococcus granulosus | bloom syndrome protein | 0.0023 | 0.0628 | 0.0866 |
Trichomonas vaginalis | rotamase, putative | 0.0034 | 0.1121 | 0.9262 |
Leishmania major | hypothetical protein, conserved | 0.0036 | 0.1193 | 0.9942 |
Echinococcus granulosus | neutral alpha glucosidase AB | 0.0036 | 0.12 | 0.1655 |
Trichomonas vaginalis | DNA helicase recq1, putative | 0.0023 | 0.0628 | 0.4656 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0036 | 0.1193 | 0.1645 |
Trichomonas vaginalis | neutral alpha-glucosidase ab precursor, putative | 0.0036 | 0.12 | 1 |
Leishmania major | peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative | 0.0033 | 0.1084 | 0.9007 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0013 | 0.017 | 0.0373 |
Trypanosoma cruzi | peptidyl-prolyl cis-trans isomerase | 0.0033 | 0.1084 | 0.9007 |
Trichomonas vaginalis | neutral alpha-glucosidase ab precursor, putative | 0.0013 | 0.017 | 0.0373 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.1193 | 0.1715 |
Brugia malayi | Glycosyl hydrolases family 31 protein | 0.0162 | 0.6954 | 1 |
Echinococcus multilocularis | geminin | 0.0169 | 0.725 | 1 |
Echinococcus granulosus | lysosomal alpha glucosidase | 0.0162 | 0.6954 | 0.9591 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.0162 | 0.6954 | 0.9591 |
Brugia malayi | Glycosyl hydrolases family 31 protein | 0.0013 | 0.017 | 0.0244 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.0162 | 0.6954 | 0.9591 |
Giardia lamblia | Sgs1 DNA helicase, putative | 0.001 | 0.00000000020105 | 0.5 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0036 | 0.1193 | 0.1715 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0045 | 0.1635 | 0.2255 |
Leishmania major | ATP-dependent DEAD/H DNA helicase recQ, putative | 0.0013 | 0.013 | 0.0826 |
Trypanosoma brucei | glycosyl hydrolase-like protein | 0.0013 | 0.017 | 0.1168 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0036 | 0.1193 | 0.9942 |
Entamoeba histolytica | peptidyl-prolyl cis-trans isomerase, putative | 0.0033 | 0.1084 | 0.8918 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.