Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | acetylcholine receptor-related | 0.0009 | 0.0009 | 0.0016 |
Mycobacterium ulcerans | long-chain-fatty-acid-CoA ligase | 0.0023 | 0.0488 | 0.0424 |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.002 | 0.0397 | 0.0495 |
Echinococcus granulosus | serine:threonine protein kinase NLK | 0.001 | 0.0029 | 0.0036 |
Loa Loa (eye worm) | ligand-Gated ion Channel family member | 0.002 | 0.0397 | 0.0495 |
Schistosoma mansoni | neurotransmitter gated ion channel | 0.0009 | 0.0009 | 0.0016 |
Brugia malayi | AMP-binding enzyme family protein | 0.0023 | 0.0488 | 0.0608 |
Onchocerca volvulus | Huntingtin homolog | 0.0122 | 0.4001 | 1 |
Brugia malayi | Cell division protein kinase 2 | 0.001 | 0.0029 | 0.0036 |
Schistosoma mansoni | neurotransmitter gated ion channel | 0.0011 | 0.0065 | 0.011 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0023 | 0.0488 | 0.0424 |
Echinococcus granulosus | mitogen activated protein kinase 15 | 0.001 | 0.0029 | 0.0036 |
Echinococcus multilocularis | neuronal acetylcholine receptor subunit alpha 4 | 0.002 | 0.0397 | 0.0495 |
Treponema pallidum | exodeoxyribonuclease (exoA) | 0.002 | 0.0369 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0032 | 0.08 | 0.1354 |
Loa Loa (eye worm) | acetylcholine receptor protein | 0.0009 | 0.0009 | 0.0011 |
Echinococcus granulosus | gamma aminobutyric acid receptor subunit | 0.0009 | 0.0009 | 0.0011 |
Brugia malayi | hypothetical protein | 0.0009 | 0.0009 | 0.0011 |
Loa Loa (eye worm) | hypothetical protein | 0.01 | 0.3227 | 0.4022 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.0009 | 0.0011 |
Mycobacterium tuberculosis | Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) | 0.0017 | 0.0283 | 0.0068 |
Echinococcus granulosus | cyclin dependent kinase 9 | 0.0062 | 0.187 | 0.2331 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0035 | 0.0907 | 0.113 |
Brugia malayi | Iron-sulfur cluster assembly accessory protein | 0.0048 | 0.138 | 0.1719 |
Schistosoma mansoni | voltage-gated potassium channel | 0.001 | 0.0042 | 0.0072 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0397 | 0.0495 |
Schistosoma mansoni | serine/threonine protein kinase | 0.001 | 0.0029 | 0.0049 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0045 | 0.1255 | 0.1564 |
Entamoeba histolytica | acyl-coA synthetase, putative | 0.0023 | 0.0488 | 0.3151 |
Echinococcus multilocularis | DNA (apurinic or apyrimidinic site) lyase | 0.002 | 0.0369 | 0.046 |
Entamoeba histolytica | protein kinase domain containing protein | 0.0053 | 0.1547 | 1 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta, putative | 0.0292 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0397 | 0.0495 |
Wolbachia endosymbiont of Brugia malayi | exonuclease III | 0.002 | 0.0369 | 0.5 |
Brugia malayi | hypothetical protein | 0.0009 | 0.0009 | 0.0011 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0397 | 0.0495 |
Trichomonas vaginalis | voltage and ligand gated potassium channel, putative | 0.0033 | 0.0855 | 0.5661 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0065 | 0.0081 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.0009 | 0.0011 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0051 | 0.1488 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0045 | 0.1255 | 0.2123 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0032 | 0.08 | 0.0998 |
Echinococcus granulosus | potassium voltage gated channel subfamily H | 0.0036 | 0.0938 | 0.1169 |
Trypanosoma cruzi | DNA polymerase beta thumb, putative | 0.0041 | 0.1129 | 0.1103 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0065 | 0.0081 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0065 | 0.0081 |
Brugia malayi | hypothetical protein | 0.0035 | 0.0907 | 0.113 |
Echinococcus multilocularis | potassium voltage gated channel subfamily H | 0.001 | 0.0042 | 0.0053 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0035 | 0.0907 | 0.113 |
Brugia malayi | Hypothetical glycine receptor like protein T20B12.9 in chromosome III | 0.002 | 0.0397 | 0.0495 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.0009 | 0.0011 |
Chlamydia trachomatis | acylglycerophosphoethanolamine acyltransferase | 0.0017 | 0.0283 | 0.5 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0045 | 0.1255 | 0.1564 |
Schistosoma mansoni | tar DNA-binding protein | 0.0123 | 0.4028 | 0.6813 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0283 | 0.0352 |
Brugia malayi | Cation transporter family protein | 0.002 | 0.0397 | 0.0495 |
Brugia malayi | Hypothetical glycine receptor like protein T20B12.9 in chromosome III | 0.0011 | 0.0065 | 0.0081 |
Echinococcus granulosus | tar DNA binding protein | 0.0123 | 0.4028 | 0.502 |
Loa Loa (eye worm) | neuronal acetylcholine receptor protein | 0.0009 | 0.0009 | 0.0011 |
Echinococcus granulosus | glycine receptor subunit beta | 0.002 | 0.0397 | 0.0495 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0023 | 0.0488 | 0.0489 |
Brugia malayi | acetylcholine receptor, alpha-type subunit unc-38 precursor | 0.002 | 0.0397 | 0.0495 |
Onchocerca volvulus | 0.002 | 0.0397 | 0.0971 | |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0065 | 0.0081 |
Schistosoma mansoni | kinase | 0.0053 | 0.1547 | 0.2617 |
Trypanosoma brucei | DNA polymerase beta thumb, putative | 0.0041 | 0.1129 | 0.1103 |
Schistosoma mansoni | acetylcholine receptor subunit beta | 0.0009 | 0.0009 | 0.0016 |
Echinococcus granulosus | glycine receptor subunit alpha 1 | 0.002 | 0.0397 | 0.0495 |
Loa Loa (eye worm) | glutamate-gated chloride channel alpha3A subunit | 0.0009 | 0.0009 | 0.0011 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0023 | 0.0488 | 0.3151 |
Trichomonas vaginalis | voltage and ligand gated potassium channel, putative | 0.0033 | 0.0855 | 0.5661 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease | 0.002 | 0.0369 | 0.0341 |
Entamoeba histolytica | hypothetical protein | 0.0011 | 0.0065 | 0.042 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0023 | 0.0488 | 0.0424 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0065 | 0.0081 |
Trypanosoma brucei | mitogen activated protein kinase 4, putative | 0.0051 | 0.1488 | 0.1464 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0397 | 0.0495 |
Schistosoma mansoni | hypothetical protein | 0.0176 | 0.5911 | 1 |
Mycobacterium tuberculosis | Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) | 0.0023 | 0.0488 | 0.0489 |
Schistosoma mansoni | protein kinase | 0.001 | 0.0029 | 0.0049 |
Loa Loa (eye worm) | nicotinic acetylcholine receptor non-alpha subunit | 0.002 | 0.0397 | 0.0495 |
Echinococcus multilocularis | nicotinic acetylcholine receptor beta 1 subunit | 0.002 | 0.0397 | 0.0495 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.01 | 0.3227 | 0.4022 |
Schistosoma mansoni | Cys-loop ligand gated ion channel subunit | 0.0011 | 0.0065 | 0.011 |
Brugia malayi | Neurotransmitter-gated ion-channel transmembrane region family protein | 0.002 | 0.0397 | 0.0495 |
Onchocerca volvulus | 0.0011 | 0.0065 | 0.014 | |
Onchocerca volvulus | 0.0011 | 0.0065 | 0.014 | |
Schistosoma mansoni | serine/threonine kinase | 0.001 | 0.0029 | 0.0049 |
Schistosoma mansoni | Cys-loop ligand gated ion channel subunit | 0.002 | 0.0397 | 0.0672 |
Brugia malayi | Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog | 0.001 | 0.0042 | 0.0053 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.0009 | 0.0011 |
Mycobacterium ulcerans | hypothetical protein | 0.0154 | 0.5115 | 1 |
Echinococcus granulosus | DNA apurinic or apyrimidinic site lyase | 0.002 | 0.0369 | 0.046 |
Echinococcus multilocularis | glycine receptor subunit beta | 0.002 | 0.0397 | 0.0495 |
Entamoeba histolytica | exodeoxyribonuclease III, putative | 0.002 | 0.0369 | 0.2386 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0397 | 0.0495 |
Trichomonas vaginalis | ap endonuclease, putative | 0.002 | 0.0369 | 0.2331 |
Echinococcus multilocularis | cyclin dependent kinase 9 | 0.0062 | 0.187 | 0.2331 |
Onchocerca volvulus | 0.0048 | 0.138 | 0.3433 | |
Schistosoma mansoni | nAChR subunit | 0.0009 | 0.0009 | 0.0016 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0069 | 0.2104 | 0.2622 |
Schistosoma mansoni | nAChR subunit | 0.002 | 0.0397 | 0.0672 |
Echinococcus granulosus | Cell division cycle 2 protein kinase | 0.001 | 0.0029 | 0.0036 |
Echinococcus granulosus | potassium voltage gated channel subfamily H | 0.001 | 0.0042 | 0.0053 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0051 | 0.1488 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0065 | 0.0081 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0397 | 0.0495 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0051 | 0.1488 | 0.2518 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0045 | 0.1255 | 0.1564 |
Echinococcus granulosus | cyclin dependent kinase 9 | 0.0053 | 0.1547 | 0.1928 |
Onchocerca volvulus | Putative nachr subunit | 0.002 | 0.0397 | 0.0971 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.08 | 0.0998 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0123 | 0.4028 | 0.502 |
Echinococcus granulosus | glycine receptor subunit alpha 1 | 0.002 | 0.0397 | 0.0495 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0045 | 0.1255 | 0.1564 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0045 | 0.1255 | 0.2123 |
Loa Loa (eye worm) | TAR-binding protein | 0.0123 | 0.4028 | 0.502 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta, putative | 0.0292 | 1 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0176 | 0.5911 | 1 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.0138 | 0.4563 | 0.4547 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0065 | 0.0081 |
Brugia malayi | Neurotransmitter-gated ion-channel transmembrane region family protein | 0.0011 | 0.0065 | 0.0081 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0154 | 0.5115 | 1 |
Trypanosoma brucei | mitochondrial DNA polymerase beta-PAK | 0.0138 | 0.4563 | 0.4547 |
Brugia malayi | AMP-binding enzyme family protein | 0.0023 | 0.0488 | 0.0608 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0051 | 0.1488 | 1 |
Brugia malayi | exodeoxyribonuclease III family protein | 0.002 | 0.0369 | 0.046 |
Schistosoma mansoni | nAChR subunit | 0.0009 | 0.0009 | 0.0016 |
Loa Loa (eye worm) | hypothetical protein | 0.0069 | 0.2104 | 0.2622 |
Leishmania major | mitogen activated protein kinase, putative,map kinase, putative | 0.0051 | 0.1488 | 0.1464 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.0009 | 0.0011 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0032 | 0.08 | 0.0998 |
Brugia malayi | glutamate-gated chloride channel alpha3A subunit, putative | 0.0009 | 0.0009 | 0.0011 |
Brugia malayi | hypothetical protein | 0.0236 | 0.8023 | 1 |
Brugia malayi | gamma-aminobutyric-acid receptor beta subunit precursor | 0.002 | 0.0397 | 0.0495 |
Echinococcus granulosus | neuronal acetylcholine receptor subunit alpha 4 | 0.002 | 0.0397 | 0.0495 |
Echinococcus granulosus | GPCR family 2 | 0.0032 | 0.08 | 0.0998 |
Plasmodium vivax | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.002 | 0.0369 | 1 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0045 | 0.1255 | 0.1564 |
Echinococcus multilocularis | acetylcholine receptor subunit beta 1 | 0.002 | 0.0397 | 0.0495 |
Loa Loa (eye worm) | RNA binding protein | 0.0123 | 0.4028 | 0.502 |
Onchocerca volvulus | 0.0023 | 0.0488 | 0.1198 | |
Loa Loa (eye worm) | hypothetical protein | 0.0122 | 0.4001 | 0.4987 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0051 | 0.1488 | 1 |
Schistosoma mansoni | ap endonuclease | 0.002 | 0.0369 | 0.0624 |
Brugia malayi | hypothetical protein | 0.0009 | 0.0009 | 0.0011 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.0009 | 0.0011 |
Schistosoma mansoni | tar DNA-binding protein | 0.0123 | 0.4028 | 0.6813 |
Schistosoma mansoni | hypothetical protein | 0.0069 | 0.2104 | 0.3559 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0283 | 0.0352 |
Brugia malayi | Cation transporter family protein | 0.002 | 0.0397 | 0.0495 |
Schistosoma mansoni | nAChR subunit (ShAR1-beta2-like) | 0.002 | 0.0397 | 0.0672 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.0009 | 0.0011 |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.002 | 0.0397 | 0.0495 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0397 | 0.0495 |
Entamoeba histolytica | protein kinase domain containing protein | 0.001 | 0.0029 | 0.0187 |
Leishmania major | apurinic/apyrimidinic endonuclease-redox protein | 0.002 | 0.0369 | 0.0341 |
Echinococcus granulosus | geminin | 0.0176 | 0.5911 | 0.7368 |
Brugia malayi | acetylcholine receptor protein, alpha-like chain, putative | 0.002 | 0.0397 | 0.0495 |
Toxoplasma gondii | hypothetical protein | 0.0047 | 0.1342 | 0.8695 |
Entamoeba histolytica | hypothetical protein | 0.0035 | 0.0907 | 0.5862 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0045 | 0.1255 | 0.2123 |
Echinococcus multilocularis | glycine receptor subunit beta | 0.002 | 0.0397 | 0.0495 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0039 | 0.1054 | 0.1783 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0397 | 0.0495 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.0009 | 0.0011 |
Loa Loa (eye worm) | excitatory GABA receptor EXP-1A | 0.002 | 0.0397 | 0.0495 |
Echinococcus multilocularis | Cys loop ligand gated ion channel subunit | 0.0009 | 0.0009 | 0.0011 |
Echinococcus multilocularis | geminin | 0.0176 | 0.5911 | 0.7368 |
Echinococcus granulosus | survival motor neuron protein 1 | 0.0236 | 0.8023 | 1 |
Echinococcus multilocularis | nicotinic acetylcholine receptor a11 subunit | 0.002 | 0.0397 | 0.0495 |
Schistosoma mansoni | tar DNA-binding protein | 0.0123 | 0.4028 | 0.6813 |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.0009 | 0.0009 | 0.0011 |
Mycobacterium ulcerans | exodeoxyribonuclease III protein XthA | 0.002 | 0.0369 | 0.0179 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0488 | 0.0608 |
Schistosoma mansoni | survival motor neuron protein | 0.0048 | 0.138 | 0.2334 |
Schistosoma mansoni | nAChR subunit | 0.002 | 0.0397 | 0.0672 |
Schistosoma mansoni | hypothetical protein | 0.0032 | 0.08 | 0.1354 |
Echinococcus granulosus | voltage gated potassium channel | 0.001 | 0.0042 | 0.0053 |
Brugia malayi | RNA binding protein | 0.0123 | 0.4028 | 0.502 |
Loa Loa (eye worm) | AGC/PDK1 protein kinase | 0.001 | 0.0029 | 0.0036 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0023 | 0.0488 | 0.0424 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.0009 | 0.0011 |
Schistosoma mansoni | nAChR subunit | 0.002 | 0.0397 | 0.0672 |
Brugia malayi | Neurotransmitter-gated ion-channel transmembrane region family protein | 0.002 | 0.0397 | 0.0495 |
Mycobacterium ulcerans | long-chain fatty-acid CoA ligase | 0.0023 | 0.0488 | 0.0424 |
Onchocerca volvulus | Huntingtin homolog | 0.0122 | 0.4001 | 1 |
Onchocerca volvulus | 0.002 | 0.0397 | 0.0971 | |
Loa Loa (eye worm) | CMGC/CDK/CDK9 protein kinase | 0.0053 | 0.1547 | 0.1928 |
Trypanosoma brucei | apurinic/apyrimidinic endonuclease, putative | 0.002 | 0.0369 | 0.0341 |
Brugia malayi | Cation transporter family protein | 0.002 | 0.0397 | 0.0495 |
Echinococcus granulosus | mitogen activated protein kinase | 0.0051 | 0.1488 | 0.1855 |
Echinococcus multilocularis | glycine receptor subunit alpha 1 | 0.002 | 0.0397 | 0.0495 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0488 | 0.0608 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.0041 | 0.1129 | 0.1103 |
Schistosoma mansoni | hypothetical protein | 0.0032 | 0.08 | 0.1354 |
Mycobacterium ulcerans | long-chain-fatty-acid--CoA ligase | 0.0023 | 0.0488 | 0.0424 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.0009 | 0.0011 |
Schistosoma mansoni | nicotinic acetylcholine receptor alpha | 0.0011 | 0.0065 | 0.011 |
Brugia malayi | nicotinic acetylcholine receptor alpha subunit, putative | 0.002 | 0.0397 | 0.0495 |
Echinococcus multilocularis | glycine receptor subunit alpha 1 | 0.002 | 0.0397 | 0.0495 |
Leishmania major | mitochondrial DNA polymerase beta-PAK, putative | 0.0138 | 0.4563 | 0.4547 |
Loa Loa (eye worm) | exodeoxyribonuclease III family protein | 0.002 | 0.0369 | 0.046 |
Brugia malayi | Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog | 0.0036 | 0.0938 | 0.1169 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0397 | 0.0495 |
Schistosoma mansoni | tar DNA-binding protein | 0.0123 | 0.4028 | 0.6813 |
Onchocerca volvulus | 0.002 | 0.0397 | 0.0971 | |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.0009 | 0.0011 |
Echinococcus multilocularis | cyclin dependent kinase 9 | 0.0053 | 0.1547 | 0.1928 |
Trypanosoma cruzi | mitogen activated protein kinase 2, putative | 0.0051 | 0.1488 | 0.1464 |
Trypanosoma brucei | protein kinase, putative | 0.006 | 0.1811 | 0.1787 |
Entamoeba histolytica | hypothetical protein | 0.0035 | 0.0907 | 0.5862 |
Echinococcus multilocularis | serine:threonine protein kinase NLK | 0.001 | 0.0029 | 0.0036 |
Brugia malayi | AMP-binding enzyme family protein | 0.0023 | 0.0488 | 0.0608 |
Brugia malayi | cyclin-dependent kinase 7 homolog | 0.001 | 0.0029 | 0.0036 |
Echinococcus multilocularis | tar DNA binding protein | 0.0123 | 0.4028 | 0.502 |
Echinococcus multilocularis | nAChR subunit | 0.0011 | 0.0065 | 0.0081 |
Echinococcus multilocularis | nAChR subunit | 0.002 | 0.0397 | 0.0495 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.0009 | 0.0011 |
Schistosoma mansoni | Cys-loop ligand gated ion channel subunit | 0.002 | 0.0397 | 0.0672 |
Entamoeba histolytica | hypothetical protein | 0.0035 | 0.0907 | 0.5862 |
Echinococcus multilocularis | mitogen activated protein kinase | 0.0051 | 0.1488 | 0.1855 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0035 | 0.0907 | 0.1534 |
Plasmodium falciparum | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.002 | 0.0369 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0397 | 0.0495 |
Echinococcus multilocularis | nicotinic acetylcholine receptor subunit alpha 8 | 0.002 | 0.0397 | 0.0495 |
Brugia malayi | Neurotransmitter-gated ion-channel transmembrane region family protein | 0.0011 | 0.0065 | 0.0081 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0397 | 0.0495 |
Echinococcus granulosus | Cys loop ligand gated ion channel subunit | 0.0009 | 0.0009 | 0.0011 |
Brugia malayi | Protein kinase domain containing protein | 0.001 | 0.0029 | 0.0036 |
Schistosoma mansoni | neurotransmitter gated ion channel | 0.0009 | 0.0009 | 0.0016 |
Schistosoma mansoni | nAChR subunit (ShAR1-alpha-like) | 0.002 | 0.0397 | 0.0672 |
Echinococcus multilocularis | potassium voltage gated channel subfamily H | 0.0036 | 0.0938 | 0.1169 |
Brugia malayi | nicotinic acetylcholine receptor beta-1 chain precursor | 0.002 | 0.0397 | 0.0495 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0032 | 0.08 | 0.0998 |
Echinococcus multilocularis | nicotinic acetylcholine receptor subunit type | 0.0009 | 0.0009 | 0.0011 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0397 | 0.0495 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0023 | 0.0488 | 0.5 |
Echinococcus granulosus | glycine receptor subunit beta | 0.002 | 0.0397 | 0.0495 |
Schistosoma mansoni | hypothetical protein | 0.0035 | 0.0907 | 0.1534 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0023 | 0.0488 | 0.5 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.01 | 0.3227 | 0.4022 |
Echinococcus granulosus | nAChR subunit | 0.002 | 0.0397 | 0.0495 |
Brugia malayi | cyclin-dependent kinase 9 | 0.0053 | 0.1547 | 0.1928 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0023 | 0.0488 | 0.3151 |
Trypanosoma brucei | mitochondrial DNA polymerase beta | 0.0292 | 1 | 1 |
Brugia malayi | Neurotransmitter-gated ion-channel transmembrane region family protein | 0.002 | 0.0397 | 0.0495 |
Schistosoma mansoni | hypothetical protein | 0.0048 | 0.138 | 0.2334 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0023 | 0.0488 | 0.046 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0397 | 0.0495 |
Giardia lamblia | Kinase, CMGC MAPK | 0.0051 | 0.1488 | 1 |
Toxoplasma gondii | CMGC kinase, MAPK family (ERK) MAPK-1 | 0.0051 | 0.1488 | 1 |
Trypanosoma cruzi | mitogen activated protein kinase 4, putative | 0.0051 | 0.1488 | 0.1464 |
Echinococcus multilocularis | Cell division cycle 2 protein kinase | 0.001 | 0.0029 | 0.0036 |
Entamoeba histolytica | hypothetical protein | 0.0035 | 0.0907 | 0.5862 |
Entamoeba histolytica | cell division protein kinase 2, putative | 0.001 | 0.0029 | 0.0187 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0397 | 0.0495 |
Echinococcus granulosus | nicotinic acetylcholine receptor subunit alpha 8 | 0.002 | 0.0397 | 0.0495 |
Echinococcus granulosus | nicotinic acetylcholine receptor alpha subunit | 0.002 | 0.0397 | 0.0495 |
Brugia malayi | hypothetical protein | 0.0009 | 0.0009 | 0.0011 |
Echinococcus multilocularis | voltage gated potassium channel | 0.001 | 0.0042 | 0.0053 |
Trypanosoma cruzi | DNA polymerase beta thumb, putative | 0.0041 | 0.1129 | 0.1103 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0032 | 0.08 | 0.0998 |
Brugia malayi | hypothetical protein | 0.0122 | 0.4001 | 0.4987 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0042 | 0.0053 |
Echinococcus multilocularis | gamma aminobutyric acid receptor subunit | 0.0009 | 0.0009 | 0.0011 |
Schistosoma mansoni | hypothetical protein | 0.0032 | 0.08 | 0.1354 |
Brugia malayi | acetylcholine receptor alpha subunit precursor, putative | 0.002 | 0.0397 | 0.0495 |
Echinococcus multilocularis | nicotinic acetylcholine receptor alpha subunit | 0.002 | 0.0397 | 0.0495 |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.002 | 0.0397 | 0.0495 |
Loa Loa (eye worm) | glutamate-gated chloride channel alpha3A subunit | 0.002 | 0.0397 | 0.0495 |
Schistosoma mansoni | nAChR subunit | 0.002 | 0.0397 | 0.0672 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0397 | 0.0495 |
Brugia malayi | glutamate-gated chloride channel alpha3A subunit, putative | 0.0011 | 0.0065 | 0.0081 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0053 | 0.1547 | 0.2617 |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.002 | 0.0397 | 0.0495 |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.002 | 0.0397 | 0.0495 |
Schistosoma mansoni | nAChR subunit | 0.002 | 0.0397 | 0.0672 |
Echinococcus granulosus | nicotinic acetylcholine receptor subunit type | 0.002 | 0.0397 | 0.0495 |
Onchocerca volvulus | 0.002 | 0.0397 | 0.0971 | |
Loa Loa (eye worm) | LGC-31 protein | 0.002 | 0.0397 | 0.0495 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0039 | 0.1054 | 0.1783 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0397 | 0.0495 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0488 | 0.0608 |
Schistosoma mansoni | tar DNA-binding protein | 0.0123 | 0.4028 | 0.6813 |
Brugia malayi | Neuronal acetylcholine receptor protein, alpha-2 chain precursor | 0.0009 | 0.0009 | 0.0011 |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.002 | 0.0397 | 0.0495 |
Loa Loa (eye worm) | acetylcholine receptor alpha subunit | 0.002 | 0.0397 | 0.0495 |
Schistosoma mansoni | nAChR subunit | 0.002 | 0.0397 | 0.0672 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0397 | 0.0495 |
Leishmania major | mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 | 0.0051 | 0.1488 | 0.1464 |
Trypanosoma cruzi | mitogen-activated protein kinase 11, putative | 0.0051 | 0.1488 | 0.1464 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0123 | 0.4028 | 0.502 |
Brugia malayi | excitatory GABA receptor EXP-1A | 0.002 | 0.0397 | 0.0495 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0045 | 0.1255 | 0.1564 |
Echinococcus multilocularis | mitogen activated protein kinase 3 | 0.0051 | 0.1488 | 0.1855 |
Loa Loa (eye worm) | hypothetical protein | 0.0122 | 0.4001 | 0.4987 |
Loa Loa (eye worm) | ACC-1 protein | 0.002 | 0.0397 | 0.0495 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0023 | 0.0488 | 0.046 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0032 | 0.08 | 0.0998 |
Echinococcus granulosus | nicotinic acetylcholine receptor beta 1 subunit | 0.002 | 0.0397 | 0.0495 |
Mycobacterium ulcerans | hypothetical protein | 0.0023 | 0.0488 | 0.0424 |
Onchocerca volvulus | 0.002 | 0.0397 | 0.0971 | |
Echinococcus multilocularis | glycine receptor subunit alpha 1 | 0.002 | 0.0397 | 0.0495 |
Echinococcus granulosus | mitogen activated protein kinase 3 | 0.0051 | 0.1488 | 0.1855 |
Schistosoma mansoni | voltage-gated potassium channel | 0.001 | 0.0042 | 0.0072 |
Mycobacterium tuberculosis | Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) | 0.002 | 0.0369 | 0.0246 |
Trypanosoma cruzi | mitogen-activated protein kinase 11, putative | 0.0051 | 0.1488 | 0.1464 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.01 | 0.3227 | 0.4022 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0065 | 0.0081 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0065 | 0.0081 |
Plasmodium vivax | acyl-CoA synthetase, putative | 0.0017 | 0.0283 | 0.746 |
Schistosoma mansoni | nAChR subunit | 0.002 | 0.0397 | 0.0672 |
Echinococcus multilocularis | Cys loop ligand gated ion channel subunit | 0.002 | 0.0397 | 0.0495 |
Schistosoma mansoni | nAChR subunit (ShAR1-beta-like) | 0.002 | 0.0397 | 0.0672 |
Loa Loa (eye worm) | haspin protein kinase | 0.001 | 0.0029 | 0.0036 |
Echinococcus granulosus | nicotinic acetylcholine receptor a11 subunit | 0.002 | 0.0397 | 0.0495 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0397 | 0.0495 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease, putative | 0.002 | 0.0369 | 0.0341 |
Brugia malayi | hypothetical protein | 0.0009 | 0.0009 | 0.0011 |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.0009 | 0.0009 | 0.0011 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0397 | 0.0495 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0771 | 0.0962 |
Loa Loa (eye worm) | GABA receptor subunit | 0.0011 | 0.0065 | 0.0081 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0032 | 0.08 | 0.0998 |
Echinococcus granulosus | acetylcholine receptor subunit beta 1 | 0.002 | 0.0397 | 0.0495 |
Echinococcus multilocularis | GPCR, family 2 | 0.0032 | 0.08 | 0.0998 |
Loa Loa (eye worm) | CMGC/MAPK/ERK1 protein kinase | 0.0051 | 0.1488 | 0.1855 |
Giardia lamblia | Endonuclease/Exonuclease/phosphatase | 0.002 | 0.0369 | 0.2331 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0023 | 0.0488 | 0.0424 |
Echinococcus granulosus | glycine receptor subunit alpha 1 | 0.002 | 0.0397 | 0.0495 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0283 | 0.0352 |
Brugia malayi | TAR-binding protein | 0.0123 | 0.4028 | 0.502 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.0009 | 0.0011 |
Loa Loa (eye worm) | CMGC/CDK/CRK7 protein kinase | 0.001 | 0.0029 | 0.0036 |
Brugia malayi | MAP kinase sur-1 | 0.0051 | 0.1488 | 0.1855 |
Schistosoma mansoni | ap endonuclease | 0.002 | 0.0369 | 0.0624 |
Echinococcus granulosus | Cys loop ligand gated ion channel subunit | 0.002 | 0.0397 | 0.0495 |
Onchocerca volvulus | 0.002 | 0.0397 | 0.0971 | |
Echinococcus granulosus | nAChR subunit | 0.0011 | 0.0065 | 0.0081 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.005 | 0.1446 | 0.1421 |
Plasmodium falciparum | acyl-CoA synthetase | 0.0017 | 0.0283 | 0.746 |
Loa Loa (eye worm) | nicotinic acetylcholine receptor alpha subunit | 0.002 | 0.0397 | 0.0495 |
Trichomonas vaginalis | ap endonuclease, putative | 0.002 | 0.0369 | 0.2331 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.0009 | 0.0011 |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.0009 | 0.0009 | 0.0011 |
Brugia malayi | Acetylcholine receptor protein, alpha-like chain 1 precursor | 0.0009 | 0.0009 | 0.0011 |
Schistosoma mansoni | Cys-loop ligand gated ion channel subunit | 0.002 | 0.0397 | 0.0672 |
Echinococcus multilocularis | survival motor neuron protein 1 | 0.0236 | 0.8023 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0236 | 0.8023 | 1 |
Loa Loa (eye worm) | ACC-1 protein | 0.002 | 0.0397 | 0.0495 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0032 | 0.08 | 0.0998 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0023 | 0.0488 | 0.046 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.0009 | 0.0011 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0283 | 0.0352 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0283 | 0.0352 |
Loa Loa (eye worm) | voltage and ligand gated potassium channel | 0.0036 | 0.0938 | 0.1169 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.