Detailed information for compound 724537

Basic information

Technical information
  • TDR Targets ID: 724537
  • Name: N-butyl-2-[cyclohexyl-(2,4,6-trimethylphenyl) sulfonylamino]acetamide
  • MW: 394.571 | Formula: C21H34N2O3S
  • H donors: 1 H acceptors: 3 LogP: 4.57 Rotable bonds: 9
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCCCNC(=O)CN(S(=O)(=O)c1c(C)cc(cc1C)C)C1CCCCC1
  • InChi: 1S/C21H34N2O3S/c1-5-6-12-22-20(24)15-23(19-10-8-7-9-11-19)27(25,26)21-17(3)13-16(2)14-18(21)4/h13-14,19H,5-12,15H2,1-4H3,(H,22,24)
  • InChiKey: QRLHPRWNWLXJIR-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • N-butyl-2-[cyclohexyl-(2,4,6-trimethylphenyl)sulfonyl-amino]acetamide
  • N-butyl-2-[cyclohexyl-(2,4,6-trimethylphenyl)sulfonyl-amino]ethanamide
  • ZINC05028054

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Schistosoma mansoni transient receptor potential channel 0.001 0.0127 0.0127
Brugia malayi endochitinase 0.0074 0.1617 0.5995
Brugia malayi Glycosyl hydrolases family 18 protein 0.0011 0.0151 0.0182
Schistosoma mansoni high voltage-activated calcium channel Cav1 0.001 0.0127 0.0127
Echinococcus granulosus ryanodine receptor 44f 0.001 0.0127 0.0053
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel alpha 1 0.001 0.0127 0.0053
Echinococcus granulosus potassium voltage gated channel subfamily H 0.001 0.0127 0.0053
Loa Loa (eye worm) hypothetical protein 0.001 0.0127 0.0085
Schistosoma mansoni transient receptor potential channel 4 0.001 0.0127 0.0127
Brugia malayi Voltage-gated calcium channel, alpha subunit 0.001 0.0127 0.0085
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.001 0.0127 0.0085
Loa Loa (eye worm) hypothetical protein 0.001 0.0127 0.0085
Echinococcus granulosus short transient receptor potential channel 6 0.001 0.0127 0.0053
Echinococcus multilocularis voltage gated hydrogen channel 1 0.001 0.0127 0.0053
Loa Loa (eye worm) hypothetical protein 0.001 0.0127 0.0085
Mycobacterium ulcerans chitinase/cellulase 0.0063 0.1364 1
Echinococcus granulosus voltage gated potassium channel 0.001 0.0127 0.0053
Loa Loa (eye worm) hypothetical protein 0.001 0.0127 0.0085
Schistosoma mansoni calcium-activated potassium channel 0.001 0.0127 0.0127
Schistosoma mansoni voltage-gated potassium channel 0.001 0.0127 0.0127
Echinococcus multilocularis short transient receptor potential channel 6 0.001 0.0127 0.0053
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.001 0.0127 0.7359
Loa Loa (eye worm) hypothetical protein 0.0063 0.1364 0.4991
Loa Loa (eye worm) ryanodine receptor 0.001 0.0127 0.0085
Loa Loa (eye worm) cuticular endochitinase 0.0074 0.1617 0.5995
Brugia malayi Large-conductance calcium-activated potassium channel Slo-1 (KCNMA) alpha subunit. C. elegans slo-1 ortholog 0.001 0.0127 0.0085
Mycobacterium ulcerans chitinase/cellulase 0.0063 0.1364 1
Loa Loa (eye worm) voltage-gated potassium channel 0.001 0.0127 0.0085
Schistosoma mansoni voltage-gated potassium channel 0.001 0.0127 0.0127
Echinococcus granulosus transient receptor potential cation channel 0.001 0.0127 0.0053
Echinococcus multilocularis transient receptor potential cation channel 0.001 0.0127 0.0053
Echinococcus granulosus Potassium voltage gated channel protein Shaw 0.001 0.0127 0.0053
Echinococcus granulosus potassium voltage gated channel protein 0.001 0.0127 0.0053
Schistosoma mansoni voltage-gated potassium channel 0.001 0.0127 0.0127
Echinococcus multilocularis potassium voltage gated channel subfamily A 0.001 0.0127 0.0053
Loa Loa (eye worm) hypothetical protein 0.001 0.0127 0.0085
Echinococcus multilocularis hyperpolarization activated cyclic 0.001 0.0127 0.0053
Onchocerca volvulus Putative endochitinase 0.0083 0.1824 0.6817
Toxoplasma gondii hypothetical protein 0.0118 0.2626 1
Schistosoma mansoni two-pore calcium channel 0.001 0.0127 0.0127
Loa Loa (eye worm) voltage-dependent calcium channel 0.001 0.0127 0.0085
Schistosoma mansoni voltage-gated potassium channel 0.001 0.0127 0.0127
Schistosoma mansoni vesicular amine transporter 0.001 0.0127 0.0127
Echinococcus multilocularis hyperpolarization activated cyclic 0.001 0.0127 0.0053
Brugia malayi Voltage-gated calcium channel, T-type, alpha subunit. C. elegans cca-1 ortholog 0.001 0.0127 0.0085
Echinococcus granulosus calcium activated potassium channel 0.001 0.0127 0.0053
Echinococcus granulosus transient receptor potential cation channel 0.001 0.0127 0.0053
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit. C. elegans egl-36 ortholog 0.001 0.0127 0.0085
Loa Loa (eye worm) hypothetical protein 0.001 0.0127 0.0085
Onchocerca volvulus Putative endochitinase 0.0074 0.1617 0.5995
Schistosoma mansoni voltage-gated ion channel 0.001 0.0127 0.0127
Brugia malayi hypothetical protein 0.001 0.0127 0.0085
Schistosoma mansoni voltage-gated potassium channel 0.001 0.0127 0.0127
Loa Loa (eye worm) hypothetical protein 0.001 0.0127 0.0085
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.001 0.0127 0.0127
Schistosoma mansoni cpg binding protein 0.0032 0.0648 0.0648
Brugia malayi Voltage-gated potassium channel, Shab-family (KCNB, Kv2-like) alpha-subunit 0.001 0.0127 0.0085
Onchocerca volvulus Transient receptor potential cation channel trpm homolog 0.001 0.0127 0.0085
Echinococcus granulosus voltage dependent calcium channel 0.001 0.0127 0.0053
Echinococcus granulosus cyclic nucleotide gated cation channel 0.001 0.0127 0.0053
Echinococcus multilocularis potassium voltage gated channel protein 0.001 0.0127 0.0053
Echinococcus granulosus cpg binding protein 0.0032 0.0648 0.0578
Schistosoma mansoni hypothetical protein 0.0437 1 1
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.001 0.0127 0.0127
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.001 0.0127 0.0053
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0071 0.1529 0.5645
Onchocerca volvulus Transient receptor potential cation channel trpm homolog 0.001 0.0127 0.0085
Schistosoma mansoni voltage-gated potassium channel 0.001 0.0127 0.0127
Echinococcus granulosus cyclic nucleotide gated cation channel 0.001 0.0127 0.0053
Toxoplasma gondii histone lysine methyltransferase SET1 0.0058 0.1242 0.4461
Loa Loa (eye worm) hypothetical protein 0.0118 0.2626 1
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.001 0.0127 0.0053
Schistosoma mansoni transient receptor potential channel 0.001 0.0127 0.0127
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.001 0.0127 0.0085
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.001 0.0127 0.0127
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0009 0.0118 0.0044
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.001 0.0127 0.7359
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.001 0.0127 0.0127
Schistosoma mansoni ryanodine receptor related 0.001 0.0127 0.0127
Brugia malayi ion channel NompC 0.001 0.0127 0.0085
Plasmodium falciparum conserved protein, unknown function 0.0118 0.2626 1
Schistosoma mansoni voltage-gated potassium channel 0.001 0.0127 0.0127
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0071 0.1529 1
Onchocerca volvulus Putative chitinase 0.0011 0.0151 0.0182
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0008 0.0074 0.0074
Echinococcus granulosus transient receptor potential cation channel 0.001 0.0127 0.0053
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0071 0.1529 0.1529
Schistosoma mansoni cpg binding protein 0.0031 0.0608 0.0608
Echinococcus granulosus voltage gated sodium channel Nav1 alpha subunit 0.001 0.0127 0.0053
Schistosoma mansoni voltage-gated potassium channel 0.001 0.0127 0.0127
Schistosoma mansoni voltage-gated potassium channel 0.001 0.0127 0.0127
Echinococcus granulosus TRP transient receptor potential channel 0.001 0.0127 0.0053
Loa Loa (eye worm) hypothetical protein 0.001 0.0127 0.0085
Brugia malayi cation channel family protein 0.001 0.0127 0.0085
Brugia malayi hypothetical protein 0.0011 0.0151 0.0182
Loa Loa (eye worm) hypothetical protein 0.001 0.0127 0.0085
Schistosoma mansoni voltage-gated cation channel 0.001 0.0127 0.0127
Brugia malayi Glycosyl hydrolases family 18 protein 0.0011 0.0151 0.0182
Schistosoma mansoni 60S ribosomal protein L21 0.001 0.0127 0.0127
Plasmodium vivax hypothetical protein, conserved 0.0118 0.2626 1
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0071 0.1529 1
Echinococcus multilocularis transcription factor Dp 1 0.0041 0.0842 0.0773
Echinococcus multilocularis transient receptor potential cation channel 0.001 0.0127 0.0053
Loa Loa (eye worm) hypothetical protein 0.001 0.0127 0.0085
Brugia malayi Voltage-gated calcium channel, L-type, alpha subunit. C. elegans egl-19 ortholog 0.001 0.0127 0.0085
Brugia malayi Voltage-gated potassium channel, Shaker-family (KCNA, Kv1-like) alpha-subunit 0.001 0.0127 0.0085
Echinococcus multilocularis transient receptor potential cation channel 0.001 0.0127 0.0053
Loa Loa (eye worm) hypothetical protein 0.001 0.0127 0.0085
Schistosoma mansoni calcium channel voltage-dependent p/q type alpha 1a-related 0.001 0.0127 0.0127
Schistosoma mansoni voltage-gated potassium channel 0.001 0.0127 0.0127
Schistosoma mansoni voltage-gated potassium channel 0.001 0.0127 0.0127
Brugia malayi Endochitinase 0.0083 0.1824 0.6817
Echinococcus multilocularis Hepatocellular carcinoma associated antigen 59 0.0118 0.2626 0.2571
Echinococcus granulosus transient receptor potential gamma protein 0.001 0.0127 0.0053
Loa Loa (eye worm) hypothetical protein 0.001 0.0127 0.0085
Loa Loa (eye worm) hypothetical protein 0.001 0.0127 0.0085
Echinococcus granulosus hyperpolarization activated cyclic 0.001 0.0127 0.0053
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.001 0.0127 0.0127
Onchocerca volvulus 0.0031 0.0608 0.1992
Echinococcus multilocularis dnaJ subfamily B 0.0437 1 1
Echinococcus granulosus potassium:sodium hyperpolarization activated 0.001 0.0127 0.0053
Brugia malayi Cyclic-nucleotide gated cation channel 0.001 0.0127 0.0085
Echinococcus multilocularis transfer RNA-Gly 0.001 0.0127 0.0053
Echinococcus granulosus Glycoside hydrolase chitinase domain containing protein 1 0.0011 0.0151 0.0077
Brugia malayi Voltage-gated potassium channel, KCNQ (Kv7-like) alpha-subunit. C. elegans kqt-1 ortholog 0.001 0.0127 0.0085
Brugia malayi Ryanodine Receptor TM 4-6 family protein 0.001 0.0127 0.0085
Loa Loa (eye worm) hypothetical protein 0.001 0.0127 0.0085
Onchocerca volvulus Putative endochitinase 0.0083 0.1824 0.6817
Onchocerca volvulus 0.001 0.0127 0.0085
Echinococcus multilocularis cpg binding protein 0.0032 0.0648 0.0578
Echinococcus granulosus sodium leak channel non selective protein 0.001 0.0127 0.0053
Loa Loa (eye worm) hypothetical protein 0.001 0.0127 0.0085
Echinococcus multilocularis potassium voltage gated channel protein 0.001 0.0127 0.0053
Brugia malayi endochitinase 0.0083 0.1824 0.6817
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit 0.001 0.0127 0.0085
Echinococcus granulosus transient receptor potential cation channel 0.001 0.0127 0.0053
Echinococcus multilocularis Glycoside hydrolase, chitinase domain containing protein 1 0.0011 0.0151 0.0077
Loa Loa (eye worm) hypothetical protein 0.0011 0.0151 0.0182
Echinococcus granulosus cyclic nucleotide gated cation channel alpha 3 0.001 0.0127 0.0053
Brugia malayi voltage-dependent calcium channel 0.001 0.0127 0.0085
Echinococcus multilocularis voltage gated potassium channel 0.001 0.0127 0.0053
Brugia malayi Endochitinase 0.0011 0.0151 0.0182
Loa Loa (eye worm) microfilarial chitinase 0.0072 0.1571 0.5813
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.001 0.0127 0.0085
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0071 0.1529 0.5645
Brugia malayi F/Y-rich N-terminus family protein 0.0009 0.0115 0.0037
Echinococcus granulosus potassium voltage gated channel subfamily D 0.001 0.0127 0.0053
Echinococcus multilocularis transient receptor potential cation channel 0.001 0.0127 0.0053
Onchocerca volvulus Putative endochitinase 0.0083 0.1824 0.6817
Schistosoma mansoni voltage-gated potassium channel 0.001 0.0127 0.0127
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.001 0.0127 0.0127
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.001 0.0127 0.0053
Echinococcus multilocularis sodium leak channel non selective protein 0.001 0.0127 0.0053
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.001 0.0127 0.0127
Echinococcus multilocularis potassium large conductance calcium activated 0.001 0.0127 0.0053
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.001 0.0127 0.0053
Brugia malayi Voltage-gated calcium channel, P/Q-type, alpha subunit. C. elegans unc-2 ortholog 0.001 0.0127 0.0085
Echinococcus granulosus potassium voltage gated channel subfamily H 0.001 0.0127 0.0053
Echinococcus granulosus voltage gated hydrogen channel 1 0.001 0.0127 0.0053
Brugia malayi Voltage-gated potassium channel, Shab-family (KCNB, Kv2-like) alpha-subunit. C. elegans exp-2 ortholog 0.001 0.0127 0.0085
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.001 0.0127 0.0127
Schistosoma mansoni voltage-gated potassium channel 0.001 0.0127 0.0127
Echinococcus granulosus potassium large conductance calcium activated 0.001 0.0127 0.0053
Brugia malayi CXXC zinc finger family protein 0.0031 0.0608 0.1992
Echinococcus granulosus potassium voltage gated channel protein 0.001 0.0127 0.0053
Echinococcus multilocularis calcium activated potassium channel 0.001 0.0127 0.0053
Trichomonas vaginalis chitinase, putative 0.0011 0.0151 1
Echinococcus granulosus transient receptor potential cation channel 0.001 0.0127 0.0053
Schistosoma mansoni cpg binding protein 0.0032 0.0648 0.0648
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0071 0.1529 0.9399
Echinococcus multilocularis potassium voltage gated channel subfamily C 0.001 0.0127 0.0053
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.001 0.0127 0.0053
Onchocerca volvulus Putative endochitinase 0.0011 0.0151 0.0182
Echinococcus multilocularis transient receptor potential cation channel 0.001 0.0127 0.0053
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0071 0.1529 0.9409
Echinococcus granulosus hypothetical protein 0.001 0.0127 0.0053
Loa Loa (eye worm) hypothetical protein 0.0118 0.2626 1
Echinococcus granulosus transient receptor potential cation channel 0.001 0.0127 0.0053
Onchocerca volvulus 0.0118 0.2626 1
Brugia malayi olfactory channel protein osm-9 0.001 0.0127 0.0085
Brugia malayi cation channel family protein 0.001 0.0127 0.0085
Onchocerca volvulus 0.0118 0.2626 1
Mycobacterium tuberculosis Possible chitinase 0.0063 0.1364 0.5
Echinococcus granulosus short transient receptor potential channel 6 0.001 0.0127 0.0053
Echinococcus multilocularis potassium voltage gated channel protein 0.001 0.0127 0.0053
Echinococcus granulosus two pore calcium channel protein 1 0.001 0.0127 0.0053
Schistosoma mansoni voltage-gated potassium channel 0.001 0.0127 0.0127
Leishmania major chitinase 0.0074 0.1617 1
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.001 0.0127 0.0127
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.001 0.0127 0.0053
Loa Loa (eye worm) ion channel NompC 0.001 0.0127 0.0085
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.001 0.0127 0.0127
Loa Loa (eye worm) chitinase I 0.0074 0.1617 0.5995
Loa Loa (eye worm) hypothetical protein 0.001 0.0127 0.0085
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.001 0.0127 0.0085
Loa Loa (eye worm) hypothetical protein 0.001 0.0127 0.0085
Entamoeba histolytica chitinase, putative 0.0074 0.1617 1
Echinococcus granulosus potassium voltage gated channel subfamily D 0.001 0.0127 0.0053
Loa Loa (eye worm) hypothetical protein 0.0011 0.0151 0.0182
Echinococcus multilocularis potassium voltage gated channel protein 0.001 0.0127 0.0053
Schistosoma mansoni hypothetical protein 0.0118 0.2626 0.2626
Schistosoma mansoni voltage-gated potassium channel 0.001 0.0127 0.0127
Schistosoma mansoni voltage-dependent calcium channel 0.001 0.0127 0.0127
Brugia malayi Hepatocellular carcinoma-associated antigen 59 family protein 0.0118 0.2626 1
Echinococcus multilocularis voltage dependent calcium channel 0.001 0.0127 0.0053
Schistosoma mansoni voltage-gated potassium channel 0.001 0.0127 0.0127
Echinococcus granulosus potassium channel KvQLT family member kqt 1 0.001 0.0127 0.0053
Echinococcus multilocularis voltage dependent calcium channel 0.001 0.0127 0.0053
Echinococcus granulosus potassium voltage gated channel protein 0.001 0.0127 0.0053
Schistosoma mansoni high voltage-activated calcium channel Cav2A 0.001 0.0127 0.0127
Echinococcus granulosus sodium channel protein 0.001 0.0127 0.0053
Echinococcus multilocularis transient receptor potential cation channel 0.001 0.0127 0.0053
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.001 0.0127 0.0053
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0071 0.1529 1
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0071 0.1529 0.1465
Schistosoma mansoni inositol 145-trisphosphate receptor 0.001 0.0127 0.0127
Echinococcus granulosus hyperpolarization activated cyclic 0.001 0.0127 0.0053
Echinococcus multilocularis cyclic nucleotide gated cation channel alpha 3 0.001 0.0127 0.0053
Echinococcus multilocularis TRP (transient receptor potential) channel 0.001 0.0127 0.0053
Echinococcus multilocularis short transient receptor potential channel 6 0.001 0.0127 0.0053
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.001 0.0127 0.0127
Loa Loa (eye worm) calcium channel 0.001 0.0127 0.0085
Loa Loa (eye worm) voltage-gated calcium channel 0.001 0.0127 0.0085
Brugia malayi hypothetical protein 0.0011 0.0151 0.0182
Schistosoma mansoni chitinase 0.0011 0.0151 0.0151
Echinococcus multilocularis shaker cognate 0.001 0.0127 0.0053
Loa Loa (eye worm) hypothetical protein 0.001 0.0127 0.0085
Echinococcus granulosus potassium voltage gated channel protein 0.001 0.0127 0.0053
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.001 0.0127 0.0053
Loa Loa (eye worm) CXXC zinc finger family protein 0.0031 0.0608 0.1992
Echinococcus multilocularis potassium:sodium hyperpolarization activated 0.001 0.0127 0.0053
Echinococcus multilocularis potassium voltage gated channel subfamily KQT 0.001 0.0127 0.0053
Echinococcus granulosus potassium voltage gated channel subfamily C 0.001 0.0127 0.0053
Schistosoma mansoni voltage-gated potassium channel 0.001 0.0127 0.0127
Echinococcus granulosus transcription factor Dp 1 0.0041 0.0842 0.0773
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.001 0.0127 0.0085
Echinococcus multilocularis sodium channel protein 0.001 0.0127 0.0053
Loa Loa (eye worm) hypothetical protein 0.001 0.0127 0.0085
Echinococcus multilocularis conserved hypothetical protein 0.001 0.0127 0.0053
Schistosoma mansoni transient receptor potential channel 0.001 0.0127 0.0127
Loa Loa (eye worm) voltage-gated potassium channel 0.001 0.0127 0.0085
Loa Loa (eye worm) hypothetical protein 0.001 0.0127 0.0085
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0065 0.1403 0.1403
Echinococcus multilocularis transient receptor potential gamma protein 0.001 0.0127 0.0053
Echinococcus granulosus voltage gated potassium channel 0.001 0.0127 0.0053
Echinococcus multilocularis ryanodine receptor 44f 0.001 0.0127 0.0053
Onchocerca volvulus Putative endochitinase 0.0074 0.1617 0.5995
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.001 0.0127 0.0053
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0009 0.0118 0.0044
Echinococcus multilocularis two pore calcium channel protein 1 0.001 0.0127 0.0053
Loa Loa (eye worm) histone methyltransferase 0.0009 0.0118 0.0048
Loa Loa (eye worm) glycosyl hydrolase family 18 protein 0.0011 0.0151 0.0182
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0071 0.1529 0.1465
Echinococcus granulosus Hepatocellular carcinoma associated antigen 59 0.0118 0.2626 0.2571
Brugia malayi Transient-receptor-potential like protein 0.001 0.0127 0.0085
Loa Loa (eye worm) hypothetical protein 0.001 0.0127 0.0085
Schistosoma mansoni voltage-gated potassium channel KCNQ 0.001 0.0127 0.0127
Echinococcus multilocularis voltage gated potassium channel 0.001 0.0127 0.0053
Schistosoma mansoni hypothetical protein 0.001 0.0127 0.0127
Echinococcus granulosus two pore calcium channel protein 2 0.001 0.0127 0.0053
Schistosoma mansoni voltage-gated potassium channel 0.001 0.0127 0.0127
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.001 0.0127 0.0127
Echinococcus granulosus potassium voltage gated channel protein 0.001 0.0127 0.0053
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit 0.001 0.0127 0.0085
Echinococcus granulosus voltage dependent L type calcium channel subunit|voltage dependent calcium channel 0.001 0.0127 0.0053
Loa Loa (eye worm) hypothetical protein 0.001 0.0127 0.0085
Echinococcus granulosus potassium voltage gated channel subfamily D 0.001 0.0127 0.0053
Echinococcus multilocularis two pore calcium channel protein 2 0.001 0.0127 0.0053
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel|voltage dependent L type calcium channel subu 0.001 0.0127 0.0053
Echinococcus granulosus potassium voltage gated channel subfamily A 0.001 0.0127 0.0053
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.001 0.0127 0.0053
Echinococcus granulosus voltage dependent calcium channel 0.001 0.0127 0.0053
Echinococcus granulosus shaker cognate 0.001 0.0127 0.0053

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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