Detailed information for compound 725693

Basic information

Technical information
  • TDR Targets ID: 725693
  • Name: 2-[[5-(3-chlorophenyl)-4-methyl-1,2,4-triazol -3-yl]sulfanyl]-N-(2,6-dimethylphenyl)acetami de
  • MW: 386.898 | Formula: C19H19ClN4OS
  • H donors: 1 H acceptors: 3 LogP: 4.19 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 1
  • SMILES: O=C(Nc1c(C)cccc1C)CSc1nnc(n1C)c1cccc(c1)Cl
  • InChi: 1S/C19H19ClN4OS/c1-12-6-4-7-13(2)17(12)21-16(25)11-26-19-23-22-18(24(19)3)14-8-5-9-15(20)10-14/h4-10H,11H2,1-3H3,(H,21,25)
  • InChiKey: DUTKSFNMIHLCAI-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 2-[[5-(3-chlorophenyl)-4-methyl-1,2,4-triazol-3-yl]thio]-N-(2,6-dimethylphenyl)acetamide
  • 2-[[5-(3-chlorophenyl)-4-methyl-1,2,4-triazol-3-yl]sulfanyl]-N-(2,6-dimethylphenyl)ethanamide
  • ST5415817
  • ZINC02352645

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) hypothetical protein 0.0035 0.0224 0.0203
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0075 0.0802 0.0783
Plasmodium falciparum importin beta, putative 0.0028 0.0127 0.0645
Brugia malayi mbt repeat family protein 0.0048 0.0415 0.0395
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.031 0.0356
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0021 0.0021 0.0094
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0075 0.0802 0.4077
Leishmania major mitochondrial DNA polymerase beta 0.0612 0.8465 1
Onchocerca volvulus 0.0486 0.6664 1
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0587 0.8106 1
Onchocerca volvulus 0.0113 0.1334 0.1853
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.029 0.3862 0.4549
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0075 0.0802 0.0924
Mycobacterium leprae conserved hypothetical protein 0.0113 0.1334 1
Loa Loa (eye worm) hypothetical protein 0.0113 0.1334 0.1317
Brugia malayi Flap endonuclease-1 0.0026 0.0097 0.0077
Echinococcus granulosus importin subunit beta 1 0.0028 0.0127 0.0136
Trichomonas vaginalis glucosylceramidase, putative 0.025 0.3293 0.4925
Mycobacterium ulcerans aldehyde dehydrogenase 0.0059 0.0569 0.1113
Schistosoma mansoni hypothetical protein 0.0492 0.6747 0.8318
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0055 0.051 0.049
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0113 0.1334 0.1248
Toxoplasma gondii LsmAD domain-containing protein 0.0053 0.0479 0.2136
Echinococcus multilocularis snurportin 1 0.03 0.4 0.4921
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0035 0.0226 0.0308
Loa Loa (eye worm) latrophilin receptor protein 2 0.0228 0.2976 0.2962
Mycobacterium tuberculosis Conserved protein 0.0113 0.1334 0.1248
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0062 0.0608 0.0726
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0048 0.0406 0.0456
Echinococcus multilocularis lysosomal alpha glucosidase 0.0158 0.1977 0.2419
Mycobacterium tuberculosis Conserved hypothetical protein 0.0041 0.031 0.0213
Loa Loa (eye worm) RNA binding protein 0.0261 0.3455 0.3442
Brugia malayi hypothetical protein 0.0034 0.0212 0.0191
Trichomonas vaginalis importin beta-1, putative 0.0023 0.0051 0.0045
Schistosoma mansoni terminal deoxycytidyl transferase 0.0041 0.031 0.0357
Echinococcus multilocularis lysosomal alpha glucosidase 0.0158 0.1977 0.2419
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0068 0.0692 0.0807
Echinococcus granulosus SAM and MBT domain containing protein 0.0048 0.0415 0.0506
Schistosoma mansoni ap endonuclease 0.0075 0.0802 0.0965
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0427 0.5817 0.7168
Schistosoma mansoni hypothetical protein 0.0032 0.0179 0.0195
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0075 0.0802 0.071
Schistosoma mansoni tar DNA-binding protein 0.0261 0.3455 0.4247
Echinococcus granulosus histone acetyltransferase KAT2B 0.0176 0.224 0.2851
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0232 0.0318
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0062 0.0608 0.2716
Trypanosoma brucei DNA polymerase IV, putative 0.0041 0.031 0.0356
Giardia lamblia GTOR 0.0048 0.0406 0.198
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0113 0.1334 0.2921
Echinococcus multilocularis dna polymerase eta 0.0041 0.031 0.0357
Schistosoma mansoni aldehyde dehydrogenase 0.0059 0.0569 0.0678
Mycobacterium ulcerans aldehyde dehydrogenase 0.0059 0.0569 0.1113
Echinococcus granulosus flap endonuclease 1 0.0026 0.0097 0.0098
Mycobacterium tuberculosis Probable lipase LipE 0.0113 0.1334 0.1248
Leishmania major DNA polymerase eta, putative 0.0041 0.031 0.0342
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0061 0.0598 0.0714
Echinococcus granulosus dnaJ subfamily B 0.0395 0.5365 0.6866
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0086 0.0955 0.1119
Trypanosoma brucei DNA polymerase IV, putative 0.0041 0.031 0.0356
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0086 0.0955 0.1106
Trypanosoma cruzi hypothetical protein, conserved 0.0113 0.1334 0.1555
Schistosoma mansoni hypothetical protein 0.03 0.4 0.4921
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0097 0.1112 0.135
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0068 0.0692 0.0807
Echinococcus multilocularis SAM and MBT domain containing protein 0.0048 0.0415 0.0487
Plasmodium falciparum flap endonuclease 1 0.0026 0.0097 0.0495
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0024 0.0064 0.0055
Echinococcus multilocularis zinc finger protein 0.0056 0.0531 0.0631
Echinococcus granulosus fetal alzheimer antigen falz 0.0048 0.0415 0.0507
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0153 0.1905 0.242
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0035 0.0226 0.0205
Trypanosoma brucei DNA polymerase IV, putative 0.0041 0.031 0.0356
Schistosoma mansoni methyl-cpg binding protein mbd 0.0035 0.023 0.0259
Loa Loa (eye worm) hypothetical protein 0.0147 0.1817 0.18
Schistosoma mansoni tar DNA-binding protein 0.0261 0.3455 0.4247
Trypanosoma cruzi cysteine peptidase, putative 0.0068 0.0692 0.0794
Schistosoma mansoni hypothetical protein 0.0308 0.4128 0.5079
Trypanosoma cruzi cysteine peptidase, putative 0.0068 0.0692 0.0794
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.031 0.0356
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0041 0.031 0.0357
Schistosoma mansoni hypothetical protein 0.0024 0.0064 0.0053
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0048 0.0415 0.0488
Schistosoma mansoni alpha-glucosidase 0.0136 0.1663 0.2031
Onchocerca volvulus 0.0052 0.0469 0.0529
Trichomonas vaginalis glucosylceramidase, putative 0.0164 0.2067 0.3079
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0021 0.0021 0.0094
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0068 0.0692 0.0807
Schistosoma mansoni sex comb on midleg homolog 0.0048 0.0415 0.0487
Echinococcus granulosus GPCR family 2 0.0228 0.2976 0.3797
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0176 0.224 0.334
Trypanosoma cruzi DNA polymerase kappa, putative 0.0041 0.031 0.0342
Trypanosoma brucei unspecified product 0.0041 0.031 0.0356
Schistosoma mansoni ferritin 0.0026 0.0098 0.0096
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.031 0.0356
Loa Loa (eye worm) hypothetical protein 0.0048 0.0415 0.0395
Brugia malayi hypothetical protein 0.0153 0.1905 0.1888
Echinococcus multilocularis beta LACTamase domain containing family member 0.0113 0.1334 0.1624
Loa Loa (eye worm) hypothetical protein 0.0079 0.0861 0.0842
Echinococcus granulosus dna polymerase eta 0.0041 0.031 0.0371
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0267 0.0371
Trypanosoma cruzi cysteine peptidase, putative 0.0068 0.0692 0.0794
Schistosoma mansoni sex comb on midleg homolog 0.0048 0.0415 0.0487
Trichomonas vaginalis glucosylceramidase, putative 0.025 0.3293 0.4925
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0075 0.0802 0.4077
Echinococcus granulosus ferritin 0.0026 0.0098 0.0099
Mycobacterium tuberculosis Probable esterase LipL 0.0113 0.1334 0.1248
Brugia malayi beta-lactamase family protein 0.0113 0.1334 0.1317
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0062 0.0608 0.0726
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0267 0.0371
Brugia malayi CXXC zinc finger family protein 0.0028 0.0122 0.0101
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0427 0.5817 0.7168
Toxoplasma gondii target of rapamycin (TOR), putative 0.0035 0.0232 0.1036
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0024 0.0064 0.0053
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.031 0.0356
Leishmania major cathepsin L-like protease 0.0068 0.0692 0.0794
Trichomonas vaginalis DNA polymerase eta, putative 0.0041 0.031 0.0434
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0267 0.0371
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0048 0.0406 0.0477
Treponema pallidum exodeoxyribonuclease (exoA) 0.0075 0.0802 1
Trichomonas vaginalis sucrase-isomaltase, putative 0.0035 0.0226 0.0308
Mycobacterium tuberculosis Conserved protein 0.0113 0.1334 0.1248
Schistosoma mansoni aldehyde dehydrogenase 0.0059 0.0569 0.0678
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0055 0.051 0.0605
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0232 0.0318
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0068 0.0692 0.0807
Trypanosoma cruzi DNA polymerase kappa, putative 0.0041 0.031 0.0342
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0075 0.0802 0.4012
Echinococcus granulosus histone acetyltransferase KAT2B 0.0566 0.7803 1
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.0226 0.0308
Mycobacterium ulcerans hypothetical protein 0.0113 0.1334 0.2921
Entamoeba histolytica acetyltransferase, GNAT family 0.0157 0.1967 1
Trypanosoma brucei DNA polymerase kappa, putative 0.0028 0.0129 0.0142
Brugia malayi Pre-SET motif family protein 0.0427 0.5823 0.5817
Echinococcus multilocularis ferritin 0.0026 0.0098 0.0096
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.014 0.1717 0.218
Loa Loa (eye worm) hypothetical protein 0.0052 0.0469 0.0449
Trichomonas vaginalis PIKK family atypical protein kinase 0.0048 0.0406 0.058
Loa Loa (eye worm) mbt repeat family protein 0.0048 0.0415 0.0395
Echinococcus granulosus neutral alpha glucosidase AB 0.0035 0.0226 0.0263
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0228 0.2976 0.2962
Onchocerca volvulus 0.0048 0.0415 0.0447
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.03 0.4 0.3989
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0093 0.0108
Schistosoma mansoni cpg binding protein 0.0033 0.0201 0.0223
Trypanosoma cruzi ISWI complex protein 0.0032 0.0179 0.0187
Entamoeba histolytica deoxycytidyl transferase, putative 0.0041 0.031 0.1575
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.0226 0.0308
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0133 0.0168
Brugia malayi ImpB/MucB/SamB family protein 0.0041 0.031 0.0289
Schistosoma mansoni ferritin light chain 0.0026 0.0098 0.0096
Trichomonas vaginalis glucosylceramidase, putative 0.0173 0.2193 0.3269
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0075 0.0802 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0094 0.0109
Trichomonas vaginalis glucosylceramidase, putative 0.025 0.3293 0.4925
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.072 0.9996 1
Leishmania major cathepsin L-like protease 0.0068 0.0692 0.0794
Brugia malayi Bromodomain containing protein 0.0094 0.1062 0.1044
Trichomonas vaginalis flap endonuclease-1, putative 0.0026 0.0097 0.0115
Trichomonas vaginalis ap endonuclease, putative 0.0075 0.0802 0.1175
Loa Loa (eye worm) hypothetical protein 0.0113 0.1334 0.1317
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.0226 0.0308
Schistosoma mansoni tar DNA-binding protein 0.0261 0.3455 0.4247
Brugia malayi follicle stimulating hormone receptor 0.0234 0.3068 0.3054
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0038 0.0268 0.0306
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.031 0.0356
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0228 0.2976 0.3655
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0048 0.0406 0.0456
Loa Loa (eye worm) hypothetical protein 0.0041 0.031 0.0289
Trichomonas vaginalis set domain proteins, putative 0.0486 0.6664 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0068 0.0692 0.0807
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0048 0.0406 0.2066
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0158 0.1977 0.196
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0074 0.0789 0.0949
Trypanosoma brucei hypothetical protein, conserved 0.0113 0.1334 0.1568
Schistosoma mansoni ap endonuclease 0.0075 0.0802 0.0965
Echinococcus granulosus lysosomal alpha glucosidase 0.0158 0.1977 0.2513
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0267 0.0371
Schistosoma mansoni alpha-glucosidase 0.0136 0.1663 0.2031
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0176 0.224 1
Echinococcus granulosus dna polymerase kappa 0.0041 0.031 0.0371
Leishmania major hypothetical protein, conserved 0.0032 0.0179 0.0187
Trypanosoma cruzi major cysteine proteinase, putative 0.0053 0.0485 0.0549
Schistosoma mansoni transient receptor potential channel 0.0062 0.0611 0.073
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0183 0.0243
Entamoeba histolytica hypothetical protein 0.0153 0.1905 0.9685
Loa Loa (eye worm) hypothetical protein 0.0053 0.0479 0.0459
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0021 0.0021 0.0014
Echinococcus multilocularis GPCR, family 2 0.0228 0.2976 0.3655
Toxoplasma gondii HEAT repeat-containing protein 0.0028 0.0127 0.0566
Echinococcus granulosus cpg binding protein 0.0033 0.0201 0.0232
Trichomonas vaginalis D-aminoacylase, putative 0.0113 0.1334 0.1977
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0261 0.3455 0.3442
Loa Loa (eye worm) hypothetical protein 0.0104 0.1213 0.1195
Schistosoma mansoni cpg binding protein 0.0033 0.0201 0.0223
Loa Loa (eye worm) TAR-binding protein 0.0261 0.3455 0.3442
Trichomonas vaginalis histone acetyltransferase gcn5, putative 0.0021 0.0029 0.0013
Schistosoma mansoni ferritin 0.0026 0.0098 0.0096
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0068 0.0692 0.0807
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0226 0.0242
Echinococcus granulosus short transient receptor potential channel 6 0.0062 0.0611 0.0759
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.029 0.3862 0.4549
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0234 0.3068 0.3054
Leishmania major cathepsin L-like protease 0.0068 0.0692 0.0794
Giardia lamblia DINP protein human, muc B family 0.0041 0.031 0.1484
Mycobacterium ulcerans DNA polymerase IV 0.0041 0.031 0.0499
Trichomonas vaginalis glucosylceramidase, putative 0.0164 0.2067 0.3079
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0228 0.2976 0.3797
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0587 0.8106 1
Brugia malayi RNA binding protein 0.0261 0.3455 0.3442
Schistosoma mansoni myelin transcription factor 1 myt1 0.0055 0.051 0.0605
Brugia malayi Transient-receptor-potential like protein 0.0035 0.0224 0.0203
Echinococcus granulosus zinc finger protein 0.0056 0.0531 0.0656
Loa Loa (eye worm) phosphatidylinositol 3 0.0048 0.0406 0.0386
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0093 0.0108
Brugia malayi Importin beta-1 subunit 0.0028 0.0127 0.0106
Trichomonas vaginalis ap endonuclease, putative 0.0075 0.0802 0.1175
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0021 0.0021 0.0107
Mycobacterium ulcerans esterase/lipase LipP 0.0113 0.1334 0.2921
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0113 0.1334 0.1317
Brugia malayi ImpB/MucB/SamB family protein 0.0041 0.031 0.0289
Trichomonas vaginalis glucosylceramidase, putative 0.0164 0.2067 0.3079
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0041 0.031 0.0213
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0612 0.8465 1
Loa Loa (eye worm) hypothetical protein 0.0113 0.1334 0.1317
Plasmodium falciparum ataxin-2 like protein, putative 0.0053 0.0479 0.2433
Onchocerca volvulus 0.0091 0.1028 0.1384
Schistosoma mansoni cellular tumor antigen P53 0.0052 0.0469 0.0554
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0048 0.0406 0.0495
Schistosoma mansoni transient receptor potential channel 4 0.0094 0.1064 0.129
Schistosoma mansoni importin beta-1 0.0028 0.0127 0.0131
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0232 0.0318
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0055 0.051 0.0628
Echinococcus multilocularis dna polymerase kappa 0.0041 0.031 0.0357
Trypanosoma cruzi DNA polymerase eta, putative 0.0041 0.031 0.0342
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0228 0.2976 0.3655
Toxoplasma gondii histone lysine methyltransferase SET1 0.0074 0.0782 0.3491
Schistosoma mansoni hypothetical protein 0.0153 0.1905 0.233
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0068 0.0692 0.0807
Schistosoma mansoni methyl-cpg binding protein mbd 0.0035 0.023 0.0259
Mycobacterium ulcerans hypothetical protein 0.0323 0.4329 1
Plasmodium vivax hypothetical protein, conserved 0.0113 0.1334 0.5957
Echinococcus granulosus tumor protein p63 0.0355 0.4797 0.6137
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0113 0.1334 0.1624
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.014 0.1717 0.2098
Leishmania major DNA polymerase kappa, putative 0.0041 0.031 0.0342
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0048 0.0406 0.0456
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0427 0.5817 0.7447
Trichomonas vaginalis glucosylceramidase, putative 0.025 0.3293 0.4925
Schistosoma mansoni hypothetical protein 0.0228 0.2976 0.3655
Echinococcus multilocularis histone acetyltransferase MYST2 0.0055 0.051 0.0605
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0205 0.2656 0.3259
Loa Loa (eye worm) hypothetical protein 0.0055 0.051 0.049
Echinococcus granulosus beta LACTamase domain containing family member 0.0113 0.1334 0.1688
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0035 0.0226 0.1008
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0097 0.1112 0.135
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0097 0.1112 0.135
Plasmodium vivax ataxin-2 like protein, putative 0.0053 0.0479 0.2136
Brugia malayi beta-lactamase 0.0113 0.1334 0.1317
Echinococcus multilocularis transient receptor potential ion channel A 0.0091 0.102 0.1235
Loa Loa (eye worm) PHD-finger family protein 0.0043 0.0336 0.0316
Echinococcus multilocularis flap endonuclease 1 0.0026 0.0097 0.0094
Loa Loa (eye worm) pigment dispersing factor receptor c 0.072 0.9996 1
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0113 0.1334 0.1317
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0105 0.1224 0.1425
Brugia malayi Latrophilin receptor protein 2 0.0228 0.2976 0.2962
Trypanosoma brucei flap endonuclease-1 (FEN-1), putative 0.0026 0.0097 0.0105
Echinococcus granulosus histone lysine methyltransferase setb 0.0097 0.1112 0.1402
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.031 0.0356
Plasmodium vivax flap endonuclease 1, putative 0.0026 0.0097 0.0435
Loa Loa (eye worm) beta-lactamase 0.0113 0.1334 0.1317
Trichomonas vaginalis glucosylceramidase, putative 0.0164 0.2067 0.3079
Trypanosoma brucei importin beta-1 subunit, putative 0.0028 0.0127 0.0139
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0133 0.0168
Brugia malayi Glycosyl hydrolases family 31 protein 0.0035 0.0226 0.0205
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0427 0.5823 0.5817
Trypanosoma brucei DNA polymerase kappa, putative 0.0028 0.0129 0.0142
Loa Loa (eye worm) acetyltransferase 0.0587 0.8106 0.8105
Onchocerca volvulus 0.0113 0.1334 0.1853
Brugia malayi RNA, U transporter 1 0.008 0.0865 0.0846
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0228 0.2976 0.3797
Trichomonas vaginalis maltase-glucoamylase, putative 0.0035 0.0226 0.0308
Giardia lamblia Flap structure-specific endonuclease 0.0026 0.0097 0.0392
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0068 0.0692 0.0807
Trichomonas vaginalis D-aminoacylase, putative 0.0113 0.1334 0.1977
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0427 0.5817 0.7168
Loa Loa (eye worm) hypothetical protein 0.0025 0.0079 0.0058
Echinococcus multilocularis cpg binding protein 0.0033 0.0201 0.0223
Schistosoma mansoni tar DNA-binding protein 0.0261 0.3455 0.4247
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0075 0.0802 0.0924
Loa Loa (eye worm) hypothetical protein 0.0228 0.2976 0.2962
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0612 0.8465 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0068 0.0692 0.0807
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0086 0.0955 0.1106
Mycobacterium tuberculosis Conserved protein 0.0113 0.1334 0.1248
Echinococcus granulosus transient receptor potential ion channel A 0.0091 0.102 0.1283
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0048 0.0415 0.0487
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0035 0.0226 0.1148
Loa Loa (eye worm) hypothetical protein 0.0492 0.6747 0.6742
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0048 0.0406 0.0456
Trypanosoma cruzi PAB1-binding protein , putative 0.0053 0.0479 0.0542
Trypanosoma cruzi ISWI complex protein 0.0032 0.0179 0.0187
Trypanosoma brucei ISWI complex protein 0.0032 0.0179 0.0201
Trypanosoma brucei unspecified product 0.0028 0.0129 0.0142
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0048 0.0415 0.0488
Trichomonas vaginalis glucosylceramidase, putative 0.0164 0.2067 0.3079
Entamoeba histolytica hypothetical protein 0.0153 0.1905 0.9685
Brugia malayi Bromodomain containing protein 0.0171 0.2169 0.2154
Plasmodium vivax importin-beta 2, putative 0.0028 0.0127 0.0566
Trichomonas vaginalis penicillin-binding protein, putative 0.0113 0.1334 0.1977
Mycobacterium tuberculosis Probable lipase LipD 0.0113 0.1334 0.1248
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0059 0.0569 0.0476
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0086 0.0955 0.1106
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0427 0.5817 0.7168
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0232 0.0318
Echinococcus multilocularis importin subunit beta 1 0.0028 0.0127 0.0131
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0035 0.0226 0.0308
Schistosoma mansoni apoferritin-2 0.0026 0.0098 0.0096
Trichomonas vaginalis PIKK family atypical protein kinase 0.0048 0.0406 0.058
Mycobacterium leprae Probable lipase LipE 0.0113 0.1334 1
Schistosoma mansoni hypothetical protein 0.0395 0.5365 0.6609
Schistosoma mansoni ferritin light chain 0.0026 0.0098 0.0096
Trichomonas vaginalis PIKK family atypical protein kinase 0.0031 0.0168 0.0221
Schistosoma mansoni bromodomain containing protein 0.0147 0.1823 0.2229
Schistosoma mansoni bromodomain containing protein 0.0025 0.0079 0.0072
Plasmodium falciparum histone acetyltransferase GCN5 0.0157 0.1967 1
Plasmodium falciparum ataxin-2 like protein, putative 0.0053 0.0479 0.2433
Trypanosoma cruzi DNA polymerase kappa, putative 0.0041 0.031 0.0342
Brugia malayi PHD-finger family protein 0.0067 0.0689 0.067
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0075 0.0802 0.0924
Loa Loa (eye worm) bromodomain containing protein 0.0051 0.0452 0.0432
Loa Loa (eye worm) CXXC zinc finger family protein 0.0028 0.0122 0.0101
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0062 0.0608 0.0726
Loa Loa (eye worm) hypothetical protein 0.0113 0.1334 0.1317
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0094 0.0109
Toxoplasma gondii ABC1 family protein 0.0113 0.1334 0.5957
Trypanosoma brucei DNA polymerase kappa, putative 0.0028 0.0129 0.0142
Brugia malayi hypothetical protein 0.0053 0.0479 0.0459
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0048 0.0406 0.047
Giardia lamblia Histone acetyltransferase GCN5 0.0157 0.1967 1
Echinococcus granulosus transient receptor potential gamma protein 0.0094 0.1064 0.1341
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0062 0.0608 0.0695
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0048 0.0406 0.2066
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0427 0.5817 0.7447
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0232 0.0318
Mycobacterium ulcerans DNA polymerase IV 0.0041 0.031 0.0499
Plasmodium vivax SET domain protein, putative 0.0062 0.0608 0.2716
Schistosoma mansoni hypothetical protein 0.0043 0.0336 0.039
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0075 0.0802 0.0938
Schistosoma mansoni transcription factor LCR-F1 0.0153 0.1905 0.233
Onchocerca volvulus 0.0062 0.0608 0.0743
Brugia malayi Calcitonin receptor-like protein seb-1 0.072 0.9996 1
Loa Loa (eye worm) flap endonuclease-1 0.0026 0.0097 0.0077
Entamoeba histolytica Flap nuclease, putative 0.0026 0.0097 0.0495
Echinococcus multilocularis neutral alpha glucosidase AB 0.0035 0.0226 0.0253
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0427 0.5817 0.581
Schistosoma mansoni transient receptor potential channel 0.0094 0.1064 0.129
Mycobacterium ulcerans aldehyde dehydrogenase 0.0059 0.0569 0.1113
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0129 0.0162
Loa Loa (eye worm) hypothetical protein 0.0097 0.1112 0.1094
Trypanosoma cruzi cruzipain precursor, putative 0.0068 0.0692 0.0794
Loa Loa (eye worm) hypothetical protein 0.0059 0.0567 0.0547
Echinococcus multilocularis polycomb protein SCMH1 0.0048 0.0415 0.0487
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0051 0.0045
Echinococcus multilocularis tumor protein p63 0.0355 0.4797 0.5907
Schistosoma mansoni ferritin 0.0026 0.0098 0.0096
Toxoplasma gondii hypothetical protein 0.0099 0.1136 0.5071
Entamoeba histolytica hypothetical protein 0.0153 0.1905 0.9685
Trypanosoma cruzi hypothetical protein, conserved 0.0113 0.1334 0.1555
Trichomonas vaginalis PIKK family atypical protein kinase 0.0048 0.0406 0.058
Trypanosoma brucei unspecified product 0.0028 0.0129 0.0142
Loa Loa (eye worm) hypothetical protein 0.0028 0.0127 0.0106
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0129 0.0162
Echinococcus granulosus short transient receptor potential channel 6 0.0062 0.0611 0.0759
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0153 0.1905 0.233
Trypanosoma brucei glucosidase, putative 0.0035 0.0226 0.0256
Schistosoma mansoni hypothetical protein 0.0228 0.2976 0.3655
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0048 0.0406 0.047
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.031 0.0356
Trichomonas vaginalis glucosylceramidase, putative 0.025 0.3293 0.4925
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0023 0.0048 0.0046
Trichomonas vaginalis penicillin-binding protein, putative 0.0113 0.1334 0.1977
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0427 0.5817 0.7168
Echinococcus granulosus histone acetyltransferase MYST2 0.0055 0.051 0.0628
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0041 0.031 0.0371
Trichomonas vaginalis esterase, putative 0.0113 0.1334 0.1977
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0041 0.031 0.0289
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0075 0.0802 0.1003
Echinococcus granulosus expressed protein 0.0026 0.0098 0.0099
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0059 0.0569 0.0678
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0041 0.031 0.0434
Brugia malayi RNA recognition motif domain containing protein 0.0261 0.3455 0.3442
Entamoeba histolytica hypothetical protein 0.0153 0.1905 0.9685
Schistosoma mansoni DNA polymerase eta 0.0041 0.031 0.0357
Brugia malayi TAR-binding protein 0.0261 0.3455 0.3442
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0074 0.0789 0.0986
Leishmania major hypothetical protein, conserved 0.0113 0.1334 0.1555
Leishmania major flap endonuclease-1 (FEN-1), putative 0.0026 0.0097 0.009
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0232 0.0318
Trypanosoma cruzi DNA polymerase kappa, putative 0.0041 0.031 0.0342
Echinococcus multilocularis short transient receptor potential channel 6 0.0062 0.0611 0.073
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0205 0.2656 0.3385
Schistosoma mansoni hypothetical protein 0.0228 0.2976 0.3655
Brugia malayi acetyltransferase, GNAT family protein 0.0587 0.8106 0.8105
Echinococcus multilocularis transient receptor potential gamma protein 0.0094 0.1064 0.129
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0075 0.0802 0.1662
Schistosoma mansoni alpha glucosidase 0.0035 0.0226 0.0253
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.025 0.3293 0.328
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0226 0.0242
Echinococcus multilocularis TRP (transient receptor potential) channel 0.0035 0.0224 0.0251
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0427 0.5817 0.581
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0612 0.8465 1
Schistosoma mansoni zinc finger protein 0.0032 0.0179 0.0195
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0094 0.0109
Echinococcus multilocularis tar DNA binding protein 0.0261 0.3455 0.4247
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0094 0.0109
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0093 0.0108
Plasmodium vivax SET domain containing protein 0.0022 0.0041 0.0182
Schistosoma mansoni zinc finger protein 0.0056 0.0531 0.0631
Loa Loa (eye worm) hypothetical protein 0.0113 0.1334 0.1317
Trypanosoma brucei PAB1-binding protein , putative 0.0053 0.0479 0.0555
Echinococcus granulosus tar DNA binding protein 0.0261 0.3455 0.4412
Mycobacterium ulcerans beta-lactamase 0.0113 0.1334 0.2921
Brugia malayi exodeoxyribonuclease III family protein 0.0075 0.0802 0.0783
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.031 0.0356
Loa Loa (eye worm) hypothetical protein 0.0113 0.1334 0.1317
Loa Loa (eye worm) hypothetical protein 0.0094 0.1064 0.1046
Brugia malayi latrophilin 2 splice variant baaae 0.0492 0.6747 0.6742
Echinococcus multilocularis expressed protein 0.0026 0.0098 0.0096
Trichomonas vaginalis glucosylceramidase, putative 0.0164 0.2067 0.3079
Echinococcus multilocularis short transient receptor potential channel 6 0.0062 0.0611 0.073
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.031 0.0356
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0041 0.031 0.0357
Toxoplasma gondii flap structure-specific endonuclease 1, putative 0.0026 0.0097 0.0435
Mycobacterium tuberculosis Probable hydrolase 0.0113 0.1334 0.1248
Trichomonas vaginalis glucosylceramidase, putative 0.0173 0.2193 0.3269
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0035 0.0226 0.1148
Trypanosoma brucei importin beta-1 subunit, putative 0.0028 0.0127 0.0139
Trichomonas vaginalis histone acetyltransferase gcn5, putative 0.0021 0.0029 0.0013
Loa Loa (eye worm) MBCTL1 0.0055 0.051 0.049
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0232 0.0318
Onchocerca volvulus 0.0113 0.1334 0.1853
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0075 0.0802 0.0965
Schistosoma mansoni hypothetical protein 0.0228 0.2976 0.3655
Entamoeba histolytica hypothetical protein 0.0023 0.0051 0.026
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0267 0.0371
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0113 0.1334 0.1248
Loa Loa (eye worm) hypothetical protein 0.0099 0.1134 0.1116
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0133 0.0168
Trypanosoma cruzi flap endonuclease-1 (FEN-1), putative 0.0026 0.0097 0.009
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0051 0.0045
Brugia malayi beta-lactamase family protein 0.0113 0.1334 0.1317
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0048 0.0406 0.0477
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.025 0.3293 0.328
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0059 0.0568 0.0702
Schistosoma mansoni apoferritin-2 0.0026 0.0098 0.0096
Trypanosoma cruzi target of rapamycin kinase 3 0.0038 0.0268 0.0292
Trypanosoma cruzi PAB1-binding protein , putative 0.0053 0.0479 0.0542
Trichomonas vaginalis D-aminoacylase, putative 0.0113 0.1334 0.1977
Mycobacterium tuberculosis Conserved hypothetical protein 0.0323 0.4329 0.4273
Trypanosoma cruzi importin beta-1 subunit, putative 0.0023 0.0051 0.0036
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0068 0.0692 0.0807
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0035 0.023 0.0259
Onchocerca volvulus Glucosylceramidase homolog 0.0164 0.2067 0.2972
Schistosoma mansoni flap endonuclease-1 0.0024 0.0062 0.005
Brugia malayi mbt repeat family protein 0.0048 0.0415 0.0395
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.031 0.0356
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0113 0.1334 0.1248
Brugia malayi Pre-SET motif family protein 0.0062 0.0608 0.0589
Echinococcus granulosus snurportin 1 0.03 0.4 0.5113
Trichomonas vaginalis ferritin, putative 0.0026 0.0098 0.0116
Loa Loa (eye worm) hypothetical protein 0.0032 0.0179 0.0159
Toxoplasma gondii exonuclease III APE 0.0075 0.0802 0.3579
Schistosoma mansoni transient receptor potential channel 0.0062 0.0611 0.073
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0041 0.031 0.0342
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0176 0.224 1
Brugia malayi Glycosyl hydrolases family 31 protein 0.0158 0.1977 0.196
Leishmania major importin beta-1 subunit, putative 0.0023 0.0051 0.0036
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.0226 0.0308
Mycobacterium ulcerans lipase LipD 0.0113 0.1334 0.2921
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.029 0.3862 0.4557
Trypanosoma brucei DNA polymerase eta, putative 0.0041 0.031 0.0356
Trichomonas vaginalis glucosylceramidase, putative 0.025 0.3293 0.4925
Trichomonas vaginalis glucosylceramidase, putative 0.0164 0.2067 0.3079
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0059 0.0569 0.0705
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0059 0.0569 0.0649
Entamoeba histolytica Ran family GTPase 0.0021 0.0021 0.0107
Trichomonas vaginalis bromodomain-containing protein, putative 0.0176 0.224 0.334
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0068 0.0692 0.0807
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0038 0.0268 0.0292
Echinococcus granulosus polycomb protein SCMH1 0.0048 0.0415 0.0506
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0176 0.224 1
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0075 0.0802 0.3579
Loa Loa (eye worm) hypothetical protein 0.072 0.9996 1
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.0226 0.0308
Echinococcus granulosus TRP transient receptor potential channel 0.0035 0.0224 0.0261
Schistosoma mansoni ferritin 0.0026 0.0098 0.0096
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0048 0.0415 0.0447
Schistosoma mansoni tar DNA-binding protein 0.0261 0.3455 0.4247
Echinococcus granulosus methyl CpG binding domain protein 2 0.0035 0.023 0.0269
Leishmania major hypothetical protein, conserved 0.0053 0.0479 0.0542
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0113 0.1334 0.1624
Leishmania major alpha glucosidase II subunit, putative 0.0035 0.0226 0.0242
Echinococcus multilocularis dnaJ subfamily B 0.0395 0.5365 0.6609
Trichomonas vaginalis PIKK family atypical protein kinase 0.0041 0.0307 0.043
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0048 0.0406 0.0386
Schistosoma mansoni cpg binding protein 0.0028 0.0122 0.0125
Toxoplasma gondii aldehyde dehydrogenase 0.0059 0.0569 0.2542

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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