Detailed information for compound 726036

Basic information

Technical information
  • TDR Targets ID: 726036
  • Name: N-(2,3-dimethylphenyl)-4-methylpiperazine-1-c arboxamide
  • MW: 247.336 | Formula: C14H21N3O
  • H donors: 1 H acceptors: 1 LogP: 1.65 Rotable bonds: 3
    Rule of 5 violations (Lipinski): 1
  • SMILES: CN1CCN(CC1)C(=O)Nc1cccc(c1C)C
  • InChi: 1S/C14H21N3O/c1-11-5-4-6-13(12(11)2)15-14(18)17-9-7-16(3)8-10-17/h4-6H,7-10H2,1-3H3,(H,15,18)
  • InChiKey: PFRBMDNDPAPTPU-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • N-(2,3-dimethylphenyl)-4-methyl-piperazine-1-carboxamide
  • N-(2,3-dimethylphenyl)-4-methyl-1-piperazinecarboxamide
  • IVK/0014590

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi hypothetical protein 0.002 0.0034 0.0034
Trypanosoma brucei NADPH-dependent diflavin oxidoreductase 1 0.0906 1 1
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0038 0.0231 0.0231
Loa Loa (eye worm) beta-lactamase 0.0072 0.0618 0.0618
Trypanosoma cruzi hypothetical protein, conserved 0.0038 0.0231 0.0231
Trypanosoma cruzi NADPH--cytochrome P450 reductase, putative 0.0346 0.3707 0.3707
Mycobacterium tuberculosis Probable oxidoreductase 0.0103 0.0967 0.1649
Mycobacterium tuberculosis Probable hydrolase 0.0072 0.0618 0.0923
Trypanosoma brucei nitrate reductase, putative 0.0103 0.0967 0.0771
Echinococcus granulosus cytochrome b5 reductase 4 0.0103 0.0967 0.0967
Schistosoma mansoni pdz and lim domain protein 0.002 0.0034 0.0034
Trypanosoma cruzi NADPH-dependent FMN/FAD containing oxidoreductase, putative 0.0906 1 1
Brugia malayi Hypothetical 13.5 kDa protein C45G9.7 in chromosome III 0.002 0.0034 0.0034
Echinococcus granulosus Rho GTPase activating protein 21 0.002 0.0034 0.0034
Echinococcus granulosus NADH cytochrome b5 reductase 3 0.0103 0.0967 0.0967
Echinococcus multilocularis MAGUK p55 subfamily 0.002 0.0034 0.0034
Trichomonas vaginalis maltase-glucoamylase, putative 0.0038 0.0231 0.0231
Echinococcus granulosus amyloid beta A4 protein 0.002 0.0034 0.0034
Leishmania major cathepsin L-like protease 0.0065 0.0537 0.0537
Trichomonas vaginalis NADPH fad oxidoreductase, putative 0.0803 0.8841 0.8841
Echinococcus multilocularis PRKCA binding protein 0.002 0.0034 0.0034
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0072 0.0618 0.0923
Schistosoma mansoni PDZ domain protein 0.002 0.0034 0.0034
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0045 0.0315 0.0315
Entamoeba histolytica type A flavoprotein, putative 0.0346 0.3707 1
Mycobacterium tuberculosis Probable monooxygenase 0.0103 0.0967 0.1649
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0065 0.0537 0.0332
Schistosoma mansoni MAGUK homolog 0.002 0.0034 0.0034
Schistosoma mansoni afadin (af-6 protein) 0.002 0.0034 0.0034
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0076 0.0669 0.0669
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.002 0.0034 0.0034
Brugia malayi diaphorase 0.0103 0.0967 0.0967
Onchocerca volvulus Huntingtin homolog 0.0121 0.1165 1
Brugia malayi Ferm domain 0.002 0.0034 0.0034
Schistosoma mansoni hypothetical protein 0.002 0.0034 0.0034
Mycobacterium tuberculosis Probable lipase LipE 0.0072 0.0618 0.0923
Trypanosoma cruzi cysteine peptidase, putative 0.0065 0.0537 0.0537
Brugia malayi PDZ domain containing protein 0.002 0.0034 0.0034
Trypanosoma cruzi Flavodoxin/Radical SAM superfamily/Wyosine base formation, putative 0.0346 0.3707 0.3707
Onchocerca volvulus Segment polarity protein dishevelled homolog 0.002 0.0034 0.0294
Loa Loa (eye worm) transcription factor SMAD2 0.0234 0.2439 0.2439
Mycobacterium ulcerans electron transfer protein FdxB 0.0103 0.0967 0.0771
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0042 0.0286 0.0286
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0045 0.0315 0.0315
Mycobacterium ulcerans monooxygenase 0.0103 0.0967 0.0771
Brugia malayi RNA recognition motif domain containing protein 0.0062 0.051 0.051
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0036 0.0218 0.0005
Plasmodium vivax ferredoxin--NADP reductase, putative 0.0103 0.0967 0.0967
Trypanosoma cruzi cysteine peptidase, putative 0.0065 0.0537 0.0537
Onchocerca volvulus 0.002 0.0034 0.0294
Echinococcus multilocularis cell polarity protein leucine rich repeat 0.002 0.0034 0.0034
Echinococcus multilocularis protein piccolo 0.002 0.0034 0.0034
Brugia malayi hypothetical protein 0.002 0.0034 0.0034
Leishmania major reductase, putative 0.0103 0.0967 0.0967
Loa Loa (eye worm) PDZ domain-containing protein 0.002 0.0034 0.0034
Brugia malayi Synapse defective protein 1 0.002 0.0034 0.0034
Echinococcus granulosus protein lin 7 B 0.002 0.0034 0.0034
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.0315 0.0315
Loa Loa (eye worm) X11 protein 0.002 0.0034 0.0034
Onchocerca volvulus Huntingtin homolog 0.0121 0.1165 1
Schistosoma mansoni cell polarity protein 0.002 0.0034 0.0034
Echinococcus multilocularis C2 calcium dependent membrane targeting 0.002 0.0034 0.0034
Echinococcus granulosus rho guanine nucleotide exchange factor 12 0.002 0.0034 0.0034
Brugia malayi PDZ domain 0.002 0.0034 0.0034
Echinococcus multilocularis tumor protein p63 0.0332 0.3548 0.3548
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0038 0.0231 0.0623
Echinococcus granulosus multiple pdz domain protein 0.002 0.0034 0.0034
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0065 0.0537 0.0332
Brugia malayi PDZ domain 0.002 0.0034 0.0034
Echinococcus granulosus cytochrome b5 reductase 4 0.0103 0.0967 0.0967
Schistosoma mansoni inositol monophosphatase 0.0036 0.0218 0.0218
Echinococcus granulosus myeloid:lymphoid or mixed lineage leukemia 0.002 0.0034 0.0034
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0072 0.0618 0.0618
Trypanosoma brucei NADH-dependent fumarate reductase, putative 0.0103 0.0967 0.0771
Onchocerca volvulus 0.0098 0.0909 0.7803
Echinococcus granulosus ligand of numb protein x 2 0.002 0.0034 0.0034
Brugia malayi FAD binding domain containing protein 0.0906 1 1
Schistosoma mansoni hypothetical protein 0.0076 0.0669 0.0669
Loa Loa (eye worm) hypothetical protein 0.0121 0.1165 0.1165
Echinococcus granulosus syndecan binding protein syntenin 0.002 0.0034 0.0034
Echinococcus granulosus cell polarity protein 0.002 0.0034 0.0034
Entamoeba histolytica hypothetical protein 0.0076 0.0669 0.1805
Plasmodium vivax flavodoxin domain containing protein 0.0803 0.8841 0.8841
Entamoeba histolytica type A flavoprotein, putative 0.0346 0.3707 1
Schistosoma mansoni cytochrome P450 reductase 0.0906 1 1
Schistosoma mansoni alpha-glucosidase 0.0145 0.1446 0.1446
Brugia malayi beta-lactamase family protein 0.0072 0.0618 0.0618
Trichomonas vaginalis D-aminoacylase, putative 0.0072 0.0618 0.0618
Echinococcus multilocularis NADPH cytochrome P450 reductase 0.0906 1 1
Echinococcus multilocularis syndecan binding protein (syntenin) 0.002 0.0034 0.0034
Loa Loa (eye worm) cytochrome b5 reductase 4 0.0103 0.0967 0.0967
Loa Loa (eye worm) hypothetical protein 0.0072 0.0618 0.0618
Echinococcus granulosus membrane associated guanylate kinase ww and pdz 0.002 0.0034 0.0034
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0065 0.0537 0.0332
Echinococcus multilocularis microtubule associated serine:threonine protein 0.002 0.0034 0.0034
Schistosoma mansoni cell polarity protein 0.002 0.0034 0.0034
Trichomonas vaginalis sucrase-isomaltase, putative 0.0038 0.0231 0.0231
Echinococcus granulosus tumor protein p63 0.0332 0.3548 0.3548
Schistosoma mansoni NADH-cytochrome B5 reductase 0.0103 0.0967 0.0967
Echinococcus multilocularis NADH cytochrome b5 reductase 3 0.0103 0.0967 0.0967
Mycobacterium tuberculosis Possible oxygenase 0.0103 0.0967 0.1649
Echinococcus multilocularis segment polarity protein dishevelled 0.002 0.0034 0.0034
Mycobacterium tuberculosis Conserved protein 0.0072 0.0618 0.0923
Leishmania major alpha glucosidase II subunit, putative 0.0038 0.0231 0.0231
Loa Loa (eye worm) hypothetical protein 0.002 0.0034 0.0034
Echinococcus granulosus beta 1 syntrophin 0.002 0.0034 0.0034
Brugia malayi gopc protein 0.002 0.0034 0.0034
Trypanosoma brucei NADPH--cytochrome P450 reductase, putative 0.0906 1 1
Trichomonas vaginalis penicillin-binding protein, putative 0.0072 0.0618 0.0618
Echinococcus granulosus disks large 1 0.002 0.0034 0.0034
Echinococcus granulosus PDZ and LIM domain protein Zasp 0.002 0.0034 0.0034
Trichomonas vaginalis penicillin-binding protein, putative 0.0072 0.0618 0.0618
Toxoplasma gondii ferredoxin NADP+ oxidoreductase FNR 0.0103 0.0967 0.1988
Echinococcus multilocularis membrane associated guanylate kinase, WW and PDZ 0.002 0.0034 0.0034
Echinococcus granulosus SH3 and multiple ankyrin repeat domains protein 0.002 0.0034 0.0034
Echinococcus granulosus pdz domain containing protein 0.002 0.0034 0.0034
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0045 0.0315 0.0315
Echinococcus multilocularis glutamate receptor interacting protein 1 0.002 0.0034 0.0034
Giardia lamblia Hypothetical protein 0.0803 0.8841 1
Mycobacterium tuberculosis Probable esterase LipL 0.0072 0.0618 0.0923
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0065 0.0537 0.0332
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0042 0.0286 0.0286
Schistosoma mansoni 5-methyl tetrahydrofolate-homocysteine methyltransferase reductase 0.0559 0.6102 0.6102
Schistosoma mansoni cell polarity protein 0.002 0.0034 0.0034
Trichomonas vaginalis D-aminoacylase, putative 0.0072 0.0618 0.0618
Schistosoma mansoni pdz domain containing protein 0.002 0.0034 0.0034
Trypanosoma brucei NADH-dependent fumarate reductase, putative 0.0103 0.0967 0.0771
Echinococcus granulosus pdz domain containing protein 0.002 0.0034 0.0034
Trypanosoma cruzi oxidoreductase-protein, putative 0.0103 0.0967 0.0967
Echinococcus multilocularis rho guanine nucleotide exchange factor 12 0.002 0.0034 0.0034
Schistosoma mansoni alpha-glucosidase 0.0145 0.1446 0.1446
Loa Loa (eye worm) hypothetical protein 0.002 0.0034 0.0034
Trypanosoma cruzi NADH-cytochrome b5 reductase, putative 0.0103 0.0967 0.0967
Schistosoma mansoni inositol monophosphatase 0.0036 0.0218 0.0218
Brugia malayi FAD binding domain containing protein 0.0559 0.6102 0.6102
Echinococcus multilocularis segment polarity protein dishevelled 0.002 0.0034 0.0034
Echinococcus granulosus MAGUK p55 subfamily 0.002 0.0034 0.0034
Trypanosoma brucei NADH-cytochrome b5 reductase-like protein 0.0103 0.0967 0.0771
Trypanosoma brucei NADH-cytochrome b5 reductase, putative 0.0103 0.0967 0.0771
Echinococcus multilocularis Na(+):H(+) exchange regulatory cofactor NHE RF2 0.002 0.0034 0.0034
Echinococcus multilocularis tar DNA binding protein 0.0062 0.051 0.051
Trichomonas vaginalis inositol monophosphatase, putative 0.0036 0.0218 0.0218
Loa Loa (eye worm) hypothetical protein 0.0049 0.0356 0.0356
Trypanosoma brucei NADH-cytochrome b5 reductase, putative 0.0103 0.0967 0.0771
Trypanosoma brucei glucosidase, putative 0.0038 0.0231 0.0019
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0218 0.0218
Mycobacterium ulcerans lipase LipD 0.0072 0.0618 0.0415
Trypanosoma cruzi major cysteine proteinase, putative 0.0051 0.0381 0.0381
Schistosoma mansoni hypothetical protein 0.0034 0.0186 0.0186
Brugia malayi syntenin 0.002 0.0034 0.0034
Schistosoma mansoni membrane associated guanylate kinase inverted related 0.002 0.0034 0.0034
Loa Loa (eye worm) cytochrome P450 family protein 0.0059 0.0475 0.0475
Onchocerca volvulus 0.002 0.0034 0.0294
Trypanosoma cruzi NADH-dependent fumarate reductase, putative 0.0103 0.0967 0.0967
Echinococcus granulosus NADPH cytochrome P450 reductase 0.0906 1 1
Loa Loa (eye worm) hypothetical protein 0.0072 0.0618 0.0618
Onchocerca volvulus 0.002 0.0034 0.0294
Onchocerca volvulus 0.002 0.0034 0.0294
Echinococcus multilocularis multiple pdz domain protein 0.002 0.0034 0.0034
Loa Loa (eye worm) hypothetical protein 0.002 0.0034 0.0034
Loa Loa (eye worm) guanylate kinase 0.002 0.0034 0.0034
Schistosoma mansoni syntrophin 0.002 0.0034 0.0034
Loa Loa (eye worm) guanylate kinase 0.002 0.0034 0.0034
Loa Loa (eye worm) hypothetical protein 0.0072 0.0618 0.0618
Echinococcus multilocularis cytochrome b5 reductase 4 0.0103 0.0967 0.0967
Echinococcus granulosus pdz domain containing protein 0.002 0.0034 0.0034
Plasmodium vivax NADPH-cytochrome p450 reductase, putative 0.0906 1 1
Loa Loa (eye worm) syntrophin-1 0.002 0.0034 0.0034
Trypanosoma cruzi Flavodoxin/Radical SAM superfamily/Wyosine base formation, putative 0.0346 0.3707 0.3707
Brugia malayi C2 domain containing protein 0.002 0.0034 0.0034
Loa Loa (eye worm) MH2 domain-containing protein 0.0234 0.2439 0.2439
Brugia malayi interleukin-16 0.002 0.0034 0.0034
Brugia malayi Cytochrome b5-like Heme/Steroid binding domain containing protein 0.0103 0.0967 0.0967
Brugia malayi Partitioning defective-6 homolog alpha 0.002 0.0034 0.0034
Echinococcus multilocularis NADPH dependent diflavin oxidoreductase 1 0.0906 1 1
Schistosoma mansoni multiple pdz domain protein 0.002 0.0034 0.0034
Echinococcus multilocularis disks large 1 0.002 0.0034 0.0034
Schistosoma mansoni sh3 and multiple ankyrin repeat domains protein 12 (shank12) 0.002 0.0034 0.0034
Brugia malayi Syntrophin-1 0.002 0.0034 0.0034
Schistosoma mansoni cell polarity protein 0.002 0.0034 0.0034
Brugia malayi Inositol-1 0.0036 0.0218 0.0218
Brugia malayi Peripheral plasma membrane protein CASK 0.002 0.0034 0.0034
Echinococcus multilocularis pdz domain containing protein 0.002 0.0034 0.0034
Echinococcus multilocularis disks large 3 0.002 0.0034 0.0034
Brugia malayi TAR-binding protein 0.0062 0.051 0.051
Mycobacterium leprae Probable lipase LipE 0.0072 0.0618 1
Loa Loa (eye worm) hypothetical protein 0.002 0.0034 0.0034
Trichomonas vaginalis sulfite reductase, putative 0.0906 1 1
Leishmania major NADH-dependent fumarate reductase, putative 0.0103 0.0967 0.0967
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0036 0.0218 0.5
Echinococcus multilocularis glutamate receptor interacting protein 1 0.002 0.0034 0.0034
Echinococcus granulosus lysosomal alpha glucosidase 0.0169 0.1711 0.1711
Brugia malayi gamma-syntrophin-like protein SYN2 0.002 0.0034 0.0034
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0169 0.1711 0.1711
Loa Loa (eye worm) PAR-6 protein 0.002 0.0034 0.0034
Loa Loa (eye worm) hypothetical protein 0.002 0.0034 0.0034
Schistosoma mansoni hypothetical protein 0.002 0.0034 0.0034
Trypanosoma brucei NADPH-cytochrome p450 reductase, putative 0.0906 1 1
Onchocerca volvulus 0.002 0.0034 0.0294
Schistosoma mansoni membrane associated guanylate kinase inverted related 0.002 0.0034 0.0034
Brugia malayi beta-lactamase family protein 0.0072 0.0618 0.0618
Mycobacterium ulcerans hypothetical protein 0.0072 0.0618 0.0415
Trichomonas vaginalis alpha-glucosidase, putative 0.0038 0.0231 0.0231
Loa Loa (eye worm) hypothetical protein 0.0037 0.0223 0.0223
Schistosoma mansoni leucine-rich repeat protein 0.002 0.0034 0.0034
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0065 0.0537 0.0332
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0065 0.0537 0.0332
Mycobacterium ulcerans oxygenase 0.0103 0.0967 0.0771
Loa Loa (eye worm) RasGEF domain-containing protein 0.002 0.0034 0.0034
Leishmania major NADH-cytochrome b5 reductase, putative 0.0103 0.0967 0.0967
Chlamydia trachomatis Na(+)-translocating NADH-quinone reductase subunit F 0.0103 0.0967 0.1538
Trichomonas vaginalis alpha-glucosidase, putative 0.0038 0.0231 0.0231
Echinococcus multilocularis pdz domain containing protein 0.002 0.0034 0.0034
Trypanosoma cruzi oxidoreductase-like protein, putative 0.0103 0.0967 0.0967
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0038 0.0231 0.0474
Brugia malayi hypothetical protein 0.0121 0.1165 0.1165
Schistosoma mansoni lin-7-like proteins 0.002 0.0034 0.0034
Echinococcus granulosus 55 kDa erythrocyte membrane protein 0.002 0.0034 0.0034
Schistosoma mansoni hypothetical protein 0.002 0.0034 0.0034
Leishmania major NADH-cytochrome b5 reductase, putative 0.0103 0.0967 0.0967
Leishmania major hypothetical protein, conserved 0.0072 0.0618 0.0618
Entamoeba histolytica type A flavoprotein, putative 0.0346 0.3707 1
Echinococcus granulosus tar DNA binding protein 0.0062 0.051 0.051
Brugia malayi rho guanine nucleotide exchange factor 12 0.002 0.0034 0.0034
Loa Loa (eye worm) diaphorase 0.0103 0.0967 0.0967
Loa Loa (eye worm) hypothetical protein 0.0049 0.0361 0.0361
Brugia malayi 9ORF binding protein 1 0.002 0.0034 0.0034
Loa Loa (eye worm) inositol-1 0.0036 0.0218 0.0218
Onchocerca volvulus 0.002 0.0034 0.0294
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0045 0.0315 0.0315
Schistosoma mansoni lim domain 0.002 0.0034 0.0034
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.0315 0.0315
Schistosoma mansoni hypothetical protein 0.002 0.0034 0.0034
Schistosoma mansoni regulator of G protein signaling 0.002 0.0034 0.0034
Loa Loa (eye worm) PX domain-containing protein 0.002 0.0034 0.0034
Echinococcus multilocularis protein lin 7 B 0.002 0.0034 0.0034
Onchocerca volvulus 0.002 0.0034 0.0294
Loa Loa (eye worm) hypothetical protein 0.0072 0.0618 0.0618
Trypanosoma cruzi cytochrome P450 reductase, putative 0.0906 1 1
Loa Loa (eye worm) hypothetical protein 0.002 0.0034 0.0034
Echinococcus granulosus NADPH dependent diflavin oxidoreductase 1 0.0906 1 1
Trypanosoma brucei NADH-dependent fumarate reductase 0.0103 0.0967 0.0771
Echinococcus granulosus PDZ and LIM domain protein Zasp 0.002 0.0034 0.0034
Plasmodium falciparum nitric oxide synthase, putative 0.0906 1 1
Loa Loa (eye worm) hypothetical protein 0.0072 0.0618 0.0618
Toxoplasma gondii flavodoxin domain-containing protein 0.0449 0.4866 1
Loa Loa (eye worm) hypothetical protein 0.002 0.0034 0.0034
Echinococcus multilocularis pdz domain containing protein 0.002 0.0034 0.0034
Echinococcus multilocularis lysosomal alpha glucosidase 0.0169 0.1711 0.1711
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0076 0.0669 0.0669
Brugia malayi Cytochrome P450 family protein 0.0059 0.0475 0.0475
Mycobacterium tuberculosis Hypothetical oxidoreductase 0.0103 0.0967 0.1649
Onchocerca volvulus 0.002 0.0034 0.0294
Echinococcus granulosus partitioning defective 3 0.002 0.0034 0.0034
Loa Loa (eye worm) hypothetical protein 0.002 0.0034 0.0034
Schistosoma mansoni maguk P55 subfamily member 26 0.002 0.0034 0.0034
Brugia malayi Glycosyl hydrolases family 31 protein 0.0169 0.1711 0.1711
Schistosoma mansoni cytochrome B5 0.0103 0.0967 0.0967
Brugia malayi PX domain containing protein 0.002 0.0034 0.0034
Loa Loa (eye worm) hypothetical protein 0.002 0.0034 0.0034
Schistosoma mansoni leucine-rich repeat protein 0.002 0.0034 0.0034
Trypanosoma cruzi cytochrome P450, putative 0.0036 0.0212 0.0212
Trypanosoma cruzi NADH-cytochrome b5 reductase, putative 0.0103 0.0967 0.0967
Trypanosoma cruzi NADH-dependent fumarate reductase, putative 0.0103 0.0967 0.0967
Echinococcus multilocularis beta LACTamase domain containing family member 0.0072 0.0618 0.0618
Loa Loa (eye worm) hypothetical protein 0.002 0.0034 0.0034
Loa Loa (eye worm) hypothetical protein 0.002 0.0034 0.0034
Trichomonas vaginalis NADPH cytochrome P450, putative 0.0346 0.3707 0.3707
Mycobacterium tuberculosis Probable lipase LipD 0.0072 0.0618 0.0923
Schistosoma mansoni tight junction protein 0.002 0.0034 0.0034
Schistosoma mansoni rab3 interacting molecule (rim)-related 0.002 0.0034 0.0034
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0059 0.0474 0.0474
Echinococcus multilocularis SH3 and multiple ankyrin repeat domains protein 0.002 0.0034 0.0034
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0072 0.0618 0.0618
Schistosoma mansoni diflavin oxidoreductase 0.0449 0.4866 0.4866
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0065 0.0537 0.0332
Schistosoma mansoni pdz domain containing protein 0.002 0.0034 0.0034
Echinococcus granulosus C2 calcium dependent membrane targeting 0.002 0.0034 0.0034
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0218 0.0218
Echinococcus multilocularis SH3 and multiple ankyrin repeat domains protein 0.002 0.0034 0.0034
Brugia malayi protein kinase C-binding protein PICK1 0.002 0.0034 0.0034
Trypanosoma cruzi NADH-cytochrome b5 reductase, putative 0.0103 0.0967 0.0967
Schistosoma mansoni multiple pdz domain protein 0.002 0.0034 0.0034
Mycobacterium tuberculosis Possible penicillin-binding protein 0.046 0.4981 1
Loa Loa (eye worm) PDZ-domain-containing protein scribble 0.002 0.0034 0.0034
Loa Loa (eye worm) hypothetical protein 0.002 0.0034 0.0034
Echinococcus granulosus MAGUK p55 subfamily 0.002 0.0034 0.0034
Loa Loa (eye worm) cytochrome P450 family protein 0.0036 0.0212 0.0212
Loa Loa (eye worm) hypothetical protein 0.002 0.0032 0.0032
Echinococcus multilocularis myeloid:lymphoid or mixed lineage leukemia 0.002 0.0034 0.0034
Leishmania major p450 reductase, putative 0.0906 1 1
Echinococcus granulosus partitioning defective 3 0.002 0.0034 0.0034
Echinococcus granulosus neurabin 1 0.002 0.0034 0.0034
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.002 0.0034 0.0034
Plasmodium falciparum S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase, putative 0.0346 0.3707 0.3707
Echinococcus granulosus membrane associated guanylate kinase, WW and PDZ 0.002 0.0034 0.0034
Echinococcus granulosus glutamate receptor interacting protein 1 0.002 0.0034 0.0034
Echinococcus multilocularis MAGUK p55 subfamily 0.002 0.0034 0.0034
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0072 0.0618 0.0923
Echinococcus multilocularis Partitioning defective 3 protein B 0.002 0.0034 0.0034
Loa Loa (eye worm) TAR-binding protein 0.0062 0.051 0.051
Plasmodium falciparum ferredoxin--NADP reductase 0.0103 0.0967 0.0967
Loa Loa (eye worm) peripheral plasma membrane protein CASK 0.002 0.0034 0.0034
Schistosoma mansoni discs lost-related 0.002 0.0034 0.0034
Brugia malayi PDZ domain containing protein 0.002 0.0034 0.0034
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0072 0.0618 0.0618
Schistosoma mansoni dishevelled 0.002 0.0034 0.0034
Echinococcus multilocularis neutral alpha glucosidase AB 0.0038 0.0231 0.0231
Loa Loa (eye worm) hypothetical protein 0.002 0.0034 0.0034
Loa Loa (eye worm) cell junction protein LIN-7 0.002 0.0034 0.0034
Loa Loa (eye worm) gopc protein 0.002 0.0034 0.0034
Toxoplasma gondii ABC1 family protein 0.0072 0.0618 0.1271
Echinococcus multilocularis MAGUK p55 subfamily 0.002 0.0034 0.0034
Onchocerca volvulus 0.002 0.0034 0.0294
Plasmodium vivax hypothetical protein, conserved 0.0346 0.3707 0.3707
Schistosoma mansoni hypothetical protein 0.002 0.0034 0.0034
Echinococcus multilocularis beta 1 syntrophin 0.002 0.0034 0.0034
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0049 0.0361 0.0361
Loa Loa (eye worm) FAD binding domain-containing protein 0.0906 1 1
Brugia malayi PDZ domain containing protein 0.002 0.0034 0.0034
Leishmania major hypothetical protein, conserved 0.0346 0.3707 0.3707
Loa Loa (eye worm) hypothetical protein 0.002 0.0034 0.0034
Brugia malayi hypothetical protein 0.002 0.0034 0.0034
Brugia malayi Protein-tyrosine phosphatase 1 0.002 0.0034 0.0034
Leishmania major NADPH-cytochrome p450 reductase-like protein 0.0906 1 1
Schistosoma mansoni hypothetical protein 0.002 0.0034 0.0034
Entamoeba histolytica type A flavoprotein, putative 0.0346 0.3707 1
Trypanosoma cruzi hypothetical protein, conserved 0.0038 0.0231 0.0231
Brugia malayi hypothetical protein 0.002 0.0034 0.0034
Echinococcus multilocularis microtubule associated protein 2 0.0679 0.7444 0.7444
Loa Loa (eye worm) protein-tyrosine phosphatase 1 0.002 0.0034 0.0034
Echinococcus granulosus MAGUK p55 subfamily 0.002 0.0034 0.0034
Trypanosoma cruzi reductase, putative 0.0103 0.0967 0.0967
Trichomonas vaginalis D-aminoacylase, putative 0.0072 0.0618 0.0618
Schistosoma mansoni hypothetical protein 0.002 0.0034 0.0034
Echinococcus granulosus 3'partial|membrane associated guanylate kinase ww and pdz 0.002 0.0034 0.0034
Loa Loa (eye worm) hypothetical protein 0.0072 0.0618 0.0618
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0045 0.0315 0.0315
Onchocerca volvulus 0.0072 0.0618 0.5309
Echinococcus multilocularis pdz domain containing protein 0.002 0.0034 0.0034
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.002 0.0034 0.0034
Chlamydia trachomatis sulfite reductase 0.0559 0.6102 1
Loa Loa (eye worm) hypothetical protein 0.002 0.0034 0.0034
Trypanosoma cruzi NADH-dependent fumarate reductase, putative 0.0103 0.0967 0.0967
Toxoplasma gondii flavodoxin domain-containing protein 0.0449 0.4866 1
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0049 0.0361 0.0361
Echinococcus granulosus pdz domain containing protein 0.002 0.0034 0.0034
Echinococcus multilocularis PDZ and LIM domain protein Zasp 0.002 0.0034 0.0034
Schistosoma mansoni voltage-gated potassium channel 0.0046 0.033 0.033
Brugia malayi DIX domain containing protein 0.002 0.0034 0.0034
Plasmodium vivax oxidoreductase NAD-binding domain containing protein 0.0103 0.0967 0.0967
Echinococcus granulosus PDZ and LIM domain protein Zasp 0.002 0.0034 0.0034
Echinococcus multilocularis amyloid beta A4 protein 0.002 0.0034 0.0034
Schistosoma mansoni microtubule-associated protein tau 0.0679 0.7444 0.7444
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0072 0.0618 0.0923
Loa Loa (eye worm) hypothetical protein 0.002 0.0034 0.0034
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0065 0.0537 0.0332
Echinococcus multilocularis Rho GTPase activating protein 21 0.002 0.0034 0.0034
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0072 0.0618 0.0415
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0065 0.0537 0.0332
Trypanosoma cruzi NADH-dependent fumarate reductase, putative 0.0103 0.0967 0.0967
Brugia malayi Shank2E 0.002 0.0034 0.0034
Echinococcus granulosus inositol monophosphatase 1 0.0036 0.0218 0.0218
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0218 0.0005
Schistosoma mansoni alpha glucosidase 0.0038 0.0231 0.0231
Echinococcus multilocularis partitioning defective protein 6 0.002 0.0034 0.0034
Schistosoma mansoni hypothetical protein 0.002 0.0034 0.0034
Brugia malayi PDZ-domain protein scribble 0.002 0.0034 0.0034
Onchocerca volvulus 0.0103 0.0967 0.8306
Trypanosoma cruzi NADH-cytochrome b5 reductase, putative 0.0103 0.0967 0.0967
Trypanosoma cruzi cytochrome-b5 reductase, putative 0.0103 0.0967 0.0967
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.0315 0.0315
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0038 0.0231 0.0231
Brugia malayi Patj homolog 0.002 0.0034 0.0034
Mycobacterium tuberculosis Possible electron transfer protein FdxB 0.0103 0.0967 0.1649
Onchocerca volvulus 0.002 0.0034 0.0294
Trypanosoma cruzi cytochrome-b5 reductase, putative 0.0103 0.0967 0.0967
Brugia malayi RNA binding protein 0.0062 0.051 0.051
Loa Loa (eye worm) FAD binding domain-containing protein 0.0559 0.6102 0.6102
Echinococcus multilocularis methionine synthase reductase 0.0559 0.6102 0.6102
Leishmania major cytochrome-b5 reductase, putative 0.0103 0.0967 0.0967
Leishmania major cytochrome-b5 reductase, putative 0.0103 0.0967 0.0967
Schistosoma mansoni sap-97 0.002 0.0034 0.0034
Leishmania major oxidoreductase-like protein 0.0103 0.0967 0.0967
Echinococcus multilocularis ligand of numb protein x 2 0.002 0.0034 0.0034
Echinococcus granulosus microtubule associated protein 2 0.0679 0.7444 0.7444
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0036 0.0218 0.0218
Trichomonas vaginalis alpha-glucosidase, putative 0.0038 0.0231 0.0231
Plasmodium vivax hypothetical protein, conserved 0.0072 0.0618 0.0618
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0072 0.0618 0.0618
Mycobacterium ulcerans beta-lactamase 0.0072 0.0618 0.0415
Trypanosoma cruzi NADH-cytochrome b5 reductase, putative 0.0103 0.0967 0.0967
Echinococcus multilocularis lysosomal alpha glucosidase 0.0169 0.1711 0.1711
Trypanosoma brucei hypothetical protein, conserved 0.0072 0.0618 0.0415
Loa Loa (eye worm) hypothetical protein 0.002 0.0034 0.0034
Echinococcus granulosus peripheral plasma membrane protein CASK 0.002 0.0034 0.0034
Schistosoma mansoni hypothetical protein 0.002 0.0034 0.0034
Onchocerca volvulus 0.0072 0.0618 0.5309
Echinococcus multilocularis PDZ domain containing protein GIPC3 0.002 0.0034 0.0034
Echinococcus granulosus multiple pdz domain protein 0.002 0.0034 0.0034
Trypanosoma cruzi cytochrome P450, putative 0.0036 0.0212 0.0212
Onchocerca volvulus 0.0072 0.0618 0.5309
Loa Loa (eye worm) hypothetical protein 0.002 0.0034 0.0034
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0036 0.0218 0.0218
Echinococcus granulosus SH3 and multiple ankyrin repeat domains protein 0.002 0.0034 0.0034
Schistosoma mansoni voltage-gated potassium channel 0.0046 0.033 0.033
Echinococcus granulosus tight junction protein ZO 3 0.002 0.0034 0.0034
Loa Loa (eye worm) CYP4Cod1 0.0036 0.0212 0.0212
Brugia malayi MH2 domain containing protein 0.0234 0.2439 0.2439
Echinococcus granulosus Na:H exchange regulatory cofactor NHE RF2 0.002 0.0034 0.0034
Loa Loa (eye worm) hypothetical protein 0.002 0.0034 0.0034
Mycobacterium tuberculosis Conserved protein 0.0072 0.0618 0.0923
Mycobacterium ulcerans formate dehydrogenase H FdhF 0.0906 1 1
Echinococcus multilocularis partitioning defective 3 0.002 0.0034 0.0034
Brugia malayi abnormal cell lineage protein 10 (Protein lin-10), putative 0.002 0.0034 0.0034
Schistosoma mansoni Patj homolog 0.002 0.0034 0.0034
Schistosoma mansoni ATP-dependent RNA Helicase 0.002 0.0034 0.0034
Schistosoma mansoni hypothetical protein 0.002 0.0034 0.0034
Leishmania major NADH-cytochrome b5 reductase, putative 0.0103 0.0967 0.0967
Loa Loa (eye worm) hypothetical protein 0.002 0.0034 0.0034
Echinococcus granulosus Microtubule-associated serine/threonine-protein kinase 0.002 0.0034 0.0034
Brugia malayi Glycosyl hydrolases family 31 protein 0.0038 0.0231 0.0231
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0065 0.0537 0.0332
Echinococcus granulosus disks large 3 0.002 0.0034 0.0034
Echinococcus granulosus membrane associated guanylate kinase ww and pdz 0.002 0.0034 0.0034
Trypanosoma brucei NADH-cytochrome b5 reductase, putative 0.0103 0.0967 0.0771
Schistosoma mansoni multiple pdz domain protein 0.002 0.0034 0.0034
Trypanosoma cruzi NADH-dependent fumarate reductase, putative 0.0103 0.0967 0.0967
Trypanosoma cruzi cytochrome P450 reductase, putative 0.0906 1 1
Brugia malayi Neurabin protein 1 0.002 0.0034 0.0034
Brugia malayi Calcitonin receptor-like protein seb-1 0.0049 0.0361 0.0361
Schistosoma mansoni hypothetical protein 0.002 0.0034 0.0034
Brugia malayi Domain found in Dishevelled, Egl-10, and Pleckstrin family protein 0.002 0.0034 0.0034
Schistosoma mansoni protein kinase C alpha binding protein 0.002 0.0034 0.0034
Schistosoma mansoni discs large 0.002 0.0034 0.0034
Leishmania major cathepsin L-like protease 0.0065 0.0537 0.0537
Plasmodium falciparum NADPH--cytochrome P450 reductase, putative 0.0346 0.3707 0.3707
Trypanosoma cruzi hypothetical protein, conserved 0.0072 0.0618 0.0618
Schistosoma mansoni dishevelled 0.002 0.0034 0.0034
Trypanosoma cruzi p450 reductase, putative 0.0103 0.0967 0.0967
Brugia malayi beta-lactamase 0.0072 0.0618 0.0618
Echinococcus granulosus segment polarity protein dishevelled 0.002 0.0034 0.0034
Onchocerca volvulus 0.002 0.0034 0.0294
Loa Loa (eye worm) cytochrome P450 family protein 0.0036 0.0212 0.0212
Schistosoma mansoni tar DNA-binding protein 0.0062 0.051 0.051
Giardia lamblia Nitric oxide synthase, inducible 0.0803 0.8841 1
Echinococcus granulosus Partitioning defective 3 protein B 0.002 0.0034 0.0034
Schistosoma mansoni tar DNA-binding protein 0.0062 0.051 0.051
Echinococcus multilocularis tight junction protein ZO 3 0.002 0.0034 0.0034
Echinococcus multilocularis multiple pdz domain protein 0.002 0.0034 0.0034
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0065 0.0537 0.0332
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0045 0.0315 0.0315
Schistosoma mansoni transcription factor LCR-F1 0.0076 0.0669 0.0669
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0038 0.0231 0.0231
Onchocerca volvulus Big bang homolog 0.002 0.0034 0.0294
Trypanosoma cruzi p450 reductase, putative 0.0906 1 1
Echinococcus multilocularis peripheral plasma membrane protein CASK 0.002 0.0034 0.0034
Trypanosoma cruzi NADH-dependent fumarate reductase, putative 0.0103 0.0967 0.0967
Trypanosoma brucei oxidoreductase-protein, putative 0.0103 0.0967 0.0771
Echinococcus granulosus multiple pdz domain protein 0.002 0.0034 0.0034
Echinococcus granulosus PRKCA binding protein 0.002 0.0034 0.0034
Loa Loa (eye worm) hypothetical protein 0.002 0.0034 0.0034
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0036 0.0218 0.0447
Brugia malayi Cytochrome P450 family protein 0.0036 0.0212 0.0212
Echinococcus multilocularis SH3 and multiple ankyrin repeat domains protein 0.002 0.0034 0.0034
Schistosoma mansoni NADPH flavin oxidoreductase 0.0456 0.4943 0.4943
Schistosoma mansoni amyloid beta A4 protein related 0.002 0.0034 0.0034
Loa Loa (eye worm) RNA binding protein 0.0062 0.051 0.051
Schistosoma mansoni cellular tumor antigen P53 0.0049 0.0356 0.0356
Trichomonas vaginalis NADPH cytochrome P450, putative 0.0346 0.3707 0.3707
Leishmania major cathepsin L-like protease 0.0065 0.0537 0.0537
Loa Loa (eye worm) hypothetical protein 0.002 0.0034 0.0034
Toxoplasma gondii NADH-cytochrome b5 reductase 1, putative 0.0103 0.0967 0.1988
Loa Loa (eye worm) hypothetical protein 0.0121 0.1165 0.1165
Trypanosoma brucei S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase, putative 0.0346 0.3707 0.3571
Trichomonas vaginalis alpha-glucosidase, putative 0.0038 0.0231 0.0231
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.004 0.0254 0.0254
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0218 0.0218
Schistosoma mansoni membrane associated guanylate kinase inverted related 0.002 0.0034 0.0034
Schistosoma mansoni multiple pdz domain protein 0.002 0.0034 0.0034
Entamoeba histolytica hypothetical protein 0.0076 0.0669 0.1805
Entamoeba histolytica hypothetical protein 0.0076 0.0669 0.1805
Brugia malayi hypothetical protein 0.002 0.0034 0.0034
Mycobacterium ulcerans oxidoreductase 0.0103 0.0967 0.0771
Loa Loa (eye worm) hypothetical protein 0.002 0.0034 0.0034
Loa Loa (eye worm) hypothetical protein 0.0906 1 1
Brugia malayi microtubule-associated serine/threonine protein kinase 2 (MAST2) 0.002 0.0034 0.0034
Trypanosoma brucei NADH-cytochrome b5 reductase, putative 0.0103 0.0967 0.0771
Brugia malayi Cytochrome P450 family protein 0.0036 0.0212 0.0212
Mycobacterium ulcerans esterase/lipase LipP 0.0072 0.0618 0.0415
Echinococcus multilocularis 55 kDa erythrocyte membrane protein 0.002 0.0034 0.0034
Brugia malayi cell junction protein LIN-7 0.002 0.0034 0.0034
Mycobacterium ulcerans flavodoxin reductase Hmp 0.0103 0.0967 0.0771
Trypanosoma brucei NADH-cytochrome b5 reductase, putative 0.0103 0.0967 0.0771
Loa Loa (eye worm) hypothetical protein 0.002 0.0034 0.0034
Brugia malayi Guanylate kinase family protein 0.002 0.0034 0.0034
Loa Loa (eye worm) hypothetical protein 0.002 0.0034 0.0034
Onchocerca volvulus 0.0049 0.0356 0.3058
Onchocerca volvulus Arc homolog 0.002 0.0034 0.0294
Echinococcus multilocularis multiple pdz domain protein 0.002 0.0034 0.0034
Entamoeba histolytica type A flavoprotein, putative 0.0346 0.3707 1
Echinococcus multilocularis partitioning defective 3 0.002 0.0034 0.0034
Echinococcus granulosus segment polarity protein dishevelled 0.002 0.0034 0.0034
Loa Loa (eye worm) hypothetical protein 0.002 0.0034 0.0034
Loa Loa (eye worm) hypothetical protein 0.002 0.0034 0.0034
Brugia malayi hypothetical protein 0.002 0.0034 0.0034
Schistosoma mansoni maguk P55 subfamily member 35 0.002 0.0034 0.0034
Trypanosoma brucei NADH-cytochrome b5 reductase, putative 0.0103 0.0967 0.0771
Mycobacterium leprae conserved hypothetical protein 0.0072 0.0618 1
Leishmania major cytochrome P450 reductase, putative 0.0803 0.8841 0.8841
Echinococcus multilocularis 0.002 0.0034 0.0034
Trypanosoma cruzi cruzipain precursor, putative 0.0065 0.0537 0.0537
Schistosoma mansoni MAGUK homolog 0.002 0.0034 0.0034
Loa Loa (eye worm) hypothetical protein 0.002 0.0034 0.0034
Trichomonas vaginalis NADPH cytochrome P450, putative 0.0346 0.3707 0.3707
Brugia malayi RasGEF domain containing protein 0.002 0.0034 0.0034
Trypanosoma cruzi NADH-cytochrome b5 reductase, putative 0.0103 0.0967 0.0967
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0042 0.0286 0.0286
Schistosoma mansoni syntenin 0.002 0.0034 0.0034
Trichomonas vaginalis esterase, putative 0.0072 0.0618 0.0618
Brugia malayi Abnormal embryonic partitioning of cytoplasm protein 3 0.002 0.0034 0.0034
Echinococcus granulosus methionine synthase reductase 0.0559 0.6102 0.6102
Trypanosoma cruzi hypothetical protein, conserved 0.0072 0.0618 0.0618
Echinococcus granulosus beta LACTamase domain containing family member 0.0072 0.0618 0.0618
Echinococcus multilocularis PDZ and LIM domain protein Zasp 0.002 0.0034 0.0034
Trypanosoma cruzi cysteine peptidase, putative 0.0065 0.0537 0.0537
Echinococcus multilocularis inositol monophosphatase 1 0.0036 0.0218 0.0218
Schistosoma mansoni multiple pdz domain protein 0.002 0.0034 0.0034
Brugia malayi PDZ domain containing protein 0.002 0.0034 0.0034
Trypanosoma brucei NADPH--cytochrome P450 reductase, putative 0.0906 1 1
Brugia malayi hypothetical protein 0.0076 0.0669 0.0669
Mycobacterium tuberculosis Conserved protein 0.0072 0.0618 0.0923
Brugia malayi flavodoxin family protein 0.0346 0.3707 0.3707
Leishmania major NADH-dependent fumarate reductase-like protein 0.0103 0.0967 0.0967
Echinococcus granulosus SH3 and multiple ankyrin repeat domains protein 0.002 0.0034 0.0034
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0042 0.0286 0.0286
Treponema pallidum flavodoxin 0.0346 0.3707 1
Schistosoma mansoni hypothetical protein 0.002 0.0034 0.0034
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0038 0.0231 0.0623
Loa Loa (eye worm) hypothetical protein 0.002 0.0034 0.0034
Trichomonas vaginalis alpha-glucosidase, putative 0.0038 0.0231 0.0231
Loa Loa (eye worm) AGC/MAST/MAST protein kinase 0.002 0.0034 0.0034
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0036 0.0218 0.0587
Brugia malayi Guanylate kinase family protein 0.002 0.0034 0.0034
Loa Loa (eye worm) flavodoxin family protein 0.0346 0.3707 0.3707
Echinococcus granulosus neutral alpha glucosidase AB 0.0038 0.0231 0.0231
Mycobacterium ulcerans flavodoxin oxidoreductase 0.0103 0.0967 0.0771
Schistosoma mansoni tar DNA-binding protein 0.0062 0.051 0.051
Leishmania major cytochrome p450-like protein 0.0036 0.0212 0.0212
Echinococcus multilocularis neurabin 1 0.002 0.0034 0.0034
Loa Loa (eye worm) DIX domain-containing protein 0.002 0.0034 0.0034
Echinococcus multilocularis PDZ and LIM domain protein Zasp 0.002 0.0034 0.0034
Schistosoma mansoni tar DNA-binding protein 0.0062 0.051 0.051
Loa Loa (eye worm) hypothetical protein 0.0034 0.0186 0.0186
Plasmodium falciparum NADH-cytochrome b5 reductase, putative 0.0103 0.0967 0.0967
Loa Loa (eye worm) 9ORF binding protein 1 0.002 0.0034 0.0034
Trypanosoma cruzi nitrate reductase, putative 0.0103 0.0967 0.0967
Entamoeba histolytica hypothetical protein 0.0076 0.0669 0.1805
Brugia malayi latrophilin 2 splice variant baaae 0.0034 0.0186 0.0186
Loa Loa (eye worm) hypothetical protein 0.002 0.0034 0.0034
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.004 0.0254 0.0254
Trypanosoma brucei NADH-dependent fumarate reductase 0.0103 0.0967 0.0771
Echinococcus multilocularis membrane associated guanylate kinase ww and pdz 0.002 0.0034 0.0034
Trichomonas vaginalis NADPH cytochrome P450, putative 0.0346 0.3707 0.3707
Schistosoma mansoni tar DNA-binding protein 0.0062 0.051 0.051
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0062 0.051 0.051
Leishmania major nitrate reductase, putative 0.0103 0.0967 0.0967

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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