Detailed information for compound 727486

Basic information

Technical information
  • TDR Targets ID: 727486
  • Name: (7-acetyloxynaphthalen-2-yl) acetate
  • MW: 244.243 | Formula: C14H12O4
  • H donors: 0 H acceptors: 2 LogP: 2.68 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: CC(=O)Oc1ccc2c(c1)cc(cc2)OC(=O)C
  • InChi: 1S/C14H12O4/c1-9(15)17-13-5-3-11-4-6-14(18-10(2)16)8-12(11)7-13/h3-8H,1-2H3
  • InChiKey: VRMXWHJBWOVBEJ-UHFFFAOYSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

  • (7-acetoxy-2-naphthyl) acetate
  • acetic acid (7-acetoxy-2-naphthyl) ester
  • (7-acetyloxynaphthalen-2-yl) ethanoate
  • 22472-26-0
  • ZINC00291442
  • Oprea1_697901

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Schistosoma mansoni loxhd1 0.004 0.0275 0.0333
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0061 0.0534 0.0649
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0109 0.1117 0.7296
Echinococcus granulosus microtubule associated protein 2 0.0692 0.8177 1
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0074 0.0695 0.0845
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0061 0.0534 0.1923
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0271 0.0745
Loa Loa (eye worm) hypothetical protein 0.0019 0.0022 0.0014
Loa Loa (eye worm) bromodomain containing protein 0.0032 0.0184 0.0251
Schistosoma mansoni serine/threonine protein kinase 0.0095 0.0944 0.115
Brugia malayi DnaJ domain containing protein 0.0061 0.0541 0.0728
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0042 0.0307 0.1006
Onchocerca volvulus 0.0081 0.0772 0.2773
Brugia malayi Doublecortin family protein 0.004 0.0275 0.0341
Echinococcus granulosus Protein patched homolog 1 0.0044 0.0328 0.0397
Brugia malayi Inositol-1 0.0038 0.0261 0.032
Echinococcus granulosus dnaJ subfamily C 6 0.0061 0.0541 0.0657
Schistosoma mansoni hypothetical protein 0.0042 0.0309 0.0374
Entamoeba histolytica phosphofructokinase, putative 0.0109 0.1117 0.3173
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0104 0.1055 0.1286
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0029 0.0153 0.0583
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0024 0.0085 0.0234
Echinococcus granulosus survival motor neuron protein 1 0.0246 0.2772 0.3387
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0038 0.0261 0.0804
Echinococcus granulosus lysosomal alpha glucosidase 0.0169 0.1847 0.2255
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0221 0.0595
Onchocerca volvulus Serine\/threonine kinase homolog 0.0095 0.0944 0.3427
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0029 0.0153 0.0008
Brugia malayi phosphofructokinase 0.0109 0.1117 0.1569
Loa Loa (eye worm) hexokinase 0.0081 0.0772 0.1105
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0085 0.0062
Onchocerca volvulus 0.0238 0.2673 1
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.002 0.0042 0.0047
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0109 0.1117 0.4393
Trypanosoma cruzi hexokinase, putative 0.0081 0.0772 0.289
Onchocerca volvulus 0.0051 0.0408 0.1392
Trichomonas vaginalis glutaminase, putative 0.0274 0.3116 0.9309
Plasmodium vivax basic transcription factor 3b, putative 0.0035 0.0221 0.0829
Loa Loa (eye worm) hypothetical protein 0.0024 0.0085 0.0106
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0024 0.0085 0.0027
Schistosoma mansoni hypothetical protein 0.005 0.0404 0.0489
Schistosoma mansoni chromobox protein 0.007 0.0643 0.0782
Mycobacterium ulcerans hypothetical protein 0.0024 0.0085 0.0234
Echinococcus granulosus hexokinase 0.0081 0.0772 0.094
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0085 0.0234
Schistosoma mansoni microtubule-associated protein tau 0.0692 0.8177 1
Echinococcus multilocularis hexokinase 0.0081 0.0772 0.0768
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0271 0.0745
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0023 0.0081 0.0272
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0034 0.0213 0.139
Loa Loa (eye worm) transcription factor SMAD2 0.012 0.1246 0.1795
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.002 0.0042 0.0044
Brugia malayi CHE-14 protein 0.0044 0.0328 0.0418
Echinococcus granulosus hexokinase type 2 0.0081 0.0772 0.094
Echinococcus multilocularis transcription factor btf3 0.0035 0.0221 0.0218
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0096 0.0956 0.0953
Loa Loa (eye worm) hypothetical protein 0.0152 0.1632 0.2355
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0174 0.1903 0.7482
Brugia malayi hypothetical protein 0.0152 0.1632 0.2321
Schistosoma mansoni kinase 0.0048 0.038 0.046
Loa Loa (eye worm) hypothetical protein 0.002 0.0042 0.0044
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0029 0.0151 0.018
Brugia malayi Heterochromatin protein 1 0.007 0.0643 0.0877
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0083 0.0806 0.0982
Brugia malayi hexokinase type II 0.0026 0.0107 0.0094
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0153 0.039
Trichomonas vaginalis phosphofructokinase, putative 0.0109 0.1117 0.329
Brugia malayi Hexokinase family protein 0.0081 0.0772 0.1065
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0586 0.6891 0.8427
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0169 0.1847 0.2667
Leishmania major glucose-6-phosphate 1-dehydrogenase, putative 0.0218 0.2439 1
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0293 0.3346 1
Plasmodium falciparum hexokinase 0.0081 0.0772 0.3006
Brugia malayi Glycosyl hydrolases family 31 protein 0.0169 0.1847 0.2635
Brugia malayi Bromodomain containing protein 0.009 0.0881 0.1224
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0293 0.3346 1
Loa Loa (eye worm) hypothetical protein 0.0026 0.0107 0.0138
Loa Loa (eye worm) glutaminase 2 0.0274 0.3116 0.4513
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0093 0.0928 0.113
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0023 0.007 0.0067
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.0085 0.0017
Mycobacterium tuberculosis Probable glucose-6-phosphate 1-dehydrogenase Zwf2 (G6PD) 0.0076 0.0713 0.466
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0093 0.0928 0.113
Echinococcus granulosus Niemann Pick C1 protein 0.0146 0.1567 0.1913
Trichomonas vaginalis phosphofructokinase, putative 0.0109 0.1117 0.329
Schistosoma mansoni hypothetical protein 0.0042 0.0309 0.0374
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0023 0.0081 0.0222
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.003 0.0159 0.0155
Schistosoma mansoni chromobox protein 0.007 0.0643 0.0782
Echinococcus granulosus retinoic acid receptor rxr beta a 0.002 0.0042 0.0047
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0174 0.1903 0.7482
Brugia malayi hypothetical protein 0.004 0.0275 0.0341
Loa Loa (eye worm) PHD-finger family protein 0.0021 0.0047 0.0052
Echinococcus granulosus peregrin 0.0046 0.0353 0.0427
Schistosoma mansoni transcription factor btf3 0.0035 0.0221 0.0266
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.002 0.0042 0.0038
Entamoeba histolytica acetyltransferase, GNAT family 0.0157 0.1701 0.4964
Schistosoma mansoni retinoid-x-receptor (RXR) 0.002 0.0042 0.0047
Onchocerca volvulus 0.0051 0.0419 0.1432
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0029 0.0153 0.0222
Onchocerca volvulus 0.0031 0.0168 0.048
Schistosoma mansoni rab6-interacting 0.004 0.0275 0.0333
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0038 0.0261 0.0767
Loa Loa (eye worm) hypothetical protein 0.0039 0.0271 0.0377
Schistosoma mansoni lipoxygenase 0.0102 0.1037 0.1265
Trichomonas vaginalis chromobox protein, putative 0.007 0.0643 0.1864
Mycobacterium ulcerans glucose-6-phosphate 1-dehydrogenase 0.0143 0.1522 0.4866
Onchocerca volvulus 0.004 0.0275 0.0887
Mycobacterium ulcerans aldehyde dehydrogenase 0.0061 0.0534 0.1682
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0029 0.0153 0.056
Plasmodium falciparum phd finger protein, putative 0.0029 0.0151 0.055
Loa Loa (eye worm) hypothetical protein 0.0051 0.0419 0.0592
Trichomonas vaginalis phosphofructokinase, putative 0.0109 0.1117 0.329
Echinococcus granulosus histone acetyltransferase KAT2B 0.0174 0.1903 0.2324
Brugia malayi jmjC domain containing protein 0.0037 0.0248 0.0301
Trypanosoma cruzi glucose-6-phosphate 1-dehydrogenase, putative 0.0218 0.2439 1
Schistosoma mansoni alpha-glucosidase 0.0146 0.1561 0.1906
Loa Loa (eye worm) hexokinase 0.0051 0.0408 0.0577
Toxoplasma gondii hexokinase 0.0081 0.0772 0.3006
Schistosoma mansoni thyroid hormone receptor 0.002 0.0042 0.0047
Echinococcus multilocularis lysosomal alpha glucosidase 0.0169 0.1847 0.1844
Loa Loa (eye worm) hypothetical protein 0.002 0.0042 0.0044
Plasmodium falciparum basic transcription factor 3b, putative 0.0035 0.0221 0.0829
Entamoeba histolytica hypothetical protein 0.0073 0.0686 0.1855
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0093 0.0928 0.0924
Echinococcus multilocularis Niemann Pick C1 protein 0.0146 0.1567 0.1564
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0038 0.0252 0.0686
Echinococcus multilocularis 6 phosphofructokinase 0.0109 0.1117 0.1113
Mycobacterium ulcerans glucose-6-phosphate 1-dehydrogenase 0.0218 0.2439 0.7818
Schistosoma mansoni cellular tumor antigen P53 0.0051 0.0419 0.0508
Mycobacterium ulcerans hypothetical protein 0.0025 0.0094 0.0265
Entamoeba histolytica hypothetical protein 0.0073 0.0686 0.1855
Echinococcus granulosus chromobox protein 1 0.007 0.0643 0.0782
Mycobacterium ulcerans glutaminase 0.0274 0.3116 1
Echinococcus multilocularis transcription factor Dp 1 0.0038 0.0261 0.0257
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0153 0.039
Trichomonas vaginalis CAMK family protein kinase 0.0047 0.0364 0.1026
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0143 0.153 1
Brugia malayi Pre-SET motif family protein 0.003 0.0159 0.0171
Schistosoma mansoni hypothetical protein 0.0073 0.0686 0.0835
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0293 0.3346 1
Mycobacterium ulcerans citrate lyase beta subunit, CitE_2 0.0025 0.0094 0.0265
Entamoeba histolytica phosphofructokinase, putative 0.0109 0.1117 0.3173
Trichomonas vaginalis CAMK family protein kinase 0.0095 0.0944 0.277
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0085 0.0234
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0038 0.0252 0.0349
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0095 0.0944 0.115
Echinococcus multilocularis glucose 6 phosphate 1 dehydrogenase 0.0218 0.2439 0.2436
Echinococcus multilocularis sterol regulatory element binding protein 0.0044 0.0328 0.0325
Loa Loa (eye worm) hypothetical protein 0.0083 0.0806 0.1155
Brugia malayi hypothetical protein 0.0073 0.0686 0.094
Loa Loa (eye worm) acetyltransferase 0.0586 0.6891 1
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0153 0.039
Echinococcus multilocularis protein dispatched 1 0.005 0.0403 0.04
Schistosoma mansoni inositol monophosphatase 0.0038 0.0261 0.0315
Echinococcus granulosus inositol monophosphatase 1 0.0038 0.0261 0.0315
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0023 0.0081 0.0222
Trichomonas vaginalis 6-phosphogluconolactonase, putative 0.0227 0.254 0.7573
Loa Loa (eye worm) doublecortin family protein 0.004 0.0275 0.0383
Echinococcus multilocularis inositol monophosphatase 1 0.0038 0.0261 0.0258
Trypanosoma brucei transcription factor BTF3, putative 0.0035 0.0221 0.0596
Brugia malayi 6-phosphofructokinase 0.0109 0.1117 0.1569
Entamoeba histolytica acyl-CoA synthetase, putative 0.0024 0.0085 0.0012
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0023 0.0081 0.0527
Echinococcus granulosus Polycystic kidney disease protein 0.004 0.0275 0.0333
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0066 0.0598 0.0727
Trichomonas vaginalis glucosamine-6-phosphate isomerase, putative 0.0227 0.254 0.7573
Leishmania major hexokinase, putative 0.0081 0.0772 0.2931
Schistosoma mansoni transcription factor LCR-F1 0.0073 0.0686 0.0835
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.002 0.0042 0.0038
Trichomonas vaginalis bromodomain-containing protein, putative 0.0174 0.1903 0.5658
Mycobacterium ulcerans aldehyde dehydrogenase 0.0061 0.0534 0.1682
Echinococcus granulosus lysine specific demethylase 5A 0.0037 0.0248 0.0299
Mycobacterium ulcerans citrate (pro-3S)-lyase subunit beta 0.0025 0.0094 0.0265
Brugia malayi hexokinase 0.0081 0.0772 0.1065
Entamoeba histolytica serine/threonine protein kinase, putative 0.0095 0.0944 0.2643
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0109 0.1117 0.7146
Loa Loa (eye worm) hypothetical protein 0.002 0.0042 0.0044
Echinococcus multilocularis jumonji domain containing protein 0.0041 0.0289 0.0286
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0024 0.0085 0.0027
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0038 0.0261 0.0554
Loa Loa (eye worm) hypothetical protein 0.002 0.0042 0.0044
Trypanosoma cruzi hypothetical protein, conserved 0.0038 0.0252 0.0671
Toxoplasma gondii glucose-6-phosphate 1-dehydrogenase 0.0143 0.1522 0.5975
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.002 0.0042 0.0047
Schistosoma mansoni hypothetical protein 0.017 0.1854 0.2264
Mycobacterium ulcerans aldehyde dehydrogenase 0.0061 0.0534 0.1682
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0093 0.0928 0.113
Echinococcus granulosus geminin 0.017 0.1854 0.2264
Loa Loa (eye worm) hypothetical protein 0.002 0.0042 0.0044
Plasmodium vivax hypothetical protein, conserved 0.0029 0.0151 0.055
Echinococcus granulosus 6 phosphofructokinase 0.0109 0.1117 0.1362
Trypanosoma brucei hexokinase 0.0081 0.0772 0.2931
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0293 0.3346 1
Schistosoma mansoni zinc finger protein 0.0034 0.0207 0.0249
Plasmodium falciparum glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase 0.0227 0.254 1
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0132 0.0328
Trypanosoma cruzi polo-like protein kinase, putative 0.0095 0.0944 0.3623
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0038 0.0261 0.0713
Loa Loa (eye worm) hypothetical protein 0.0029 0.0151 0.0202
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0293 0.3346 1
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.002 0.0042 0.0047
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0293 0.3346 1
Entamoeba histolytica hypothetical protein 0.0073 0.0686 0.1855
Loa Loa (eye worm) hypothetical protein 0.0038 0.0263 0.0365
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.002 0.0042 0.0044
Brugia malayi Hexokinase family protein 0.0051 0.0408 0.0535
Loa Loa (eye worm) hypothetical protein 0.0055 0.0464 0.0658
Schistosoma mansoni alpha-glucosidase 0.0146 0.1561 0.1906
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0034 0.0213 0.0911
Loa Loa (eye worm) DnaJ domain-containing protein 0.0061 0.0541 0.0769
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0038 0.0252 0.0523
Loa Loa (eye worm) hypothetical protein 0.004 0.0275 0.0383
Brugia malayi PHD-finger family protein 0.0039 0.0272 0.0336
Schistosoma mansoni aldehyde dehydrogenase 0.0061 0.0534 0.0649
Trypanosoma cruzi hypothetical protein, conserved 0.0213 0.238 0.9749
Echinococcus multilocularis hexokinase 0.0081 0.0772 0.0768
Onchocerca volvulus 0.0098 0.0982 0.3573
Echinococcus granulosus nuclear receptor 2DBD gamma 0.002 0.0042 0.0047
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0029 0.0153 0.039
Plasmodium falciparum histone acetyltransferase GCN5 0.0157 0.1701 0.6684
Echinococcus granulosus sterol regulatory element binding protein 0.0044 0.0328 0.0397
Schistosoma mansoni steroid hormone receptor ad4bp 0.002 0.0042 0.0047
Plasmodium vivax 6-phosphofructokinase, putative 0.0029 0.0153 0.056
Brugia malayi Bromodomain containing protein 0.0046 0.0353 0.0453
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0143 0.153 1
Brugia malayi 6-phosphofructokinase 0.0109 0.1117 0.1569
Trichomonas vaginalis chromobox protein, putative 0.007 0.0643 0.1864
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0102 0.1035 0.2924
Trichomonas vaginalis phosphofructokinase, putative 0.0109 0.1117 0.329
Loa Loa (eye worm) hypothetical protein 0.0071 0.0655 0.0936
Loa Loa (eye worm) hexokinase 0.0081 0.0772 0.1105
Loa Loa (eye worm) hypothetical protein 0.0044 0.0328 0.046
Echinococcus granulosus PHD finger protein rhinoceros 0.0029 0.0151 0.018
Trichomonas vaginalis chromobox protein, putative 0.0042 0.0307 0.0853
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0073 0.0686 0.0835
Loa Loa (eye worm) hexokinase 0.0025 0.0098 0.0126
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.002 0.0042 0.0044
Echinococcus granulosus tumor protein p63 0.0351 0.4048 0.4949
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0159 0.019
Entamoeba histolytica transcription factor BTF3, putative 0.0035 0.0221 0.0431
Leishmania major alpha glucosidase II subunit, putative 0.0038 0.0252 0.0725
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0174 0.1903 0.5658
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0041 0.0298 0.036
Echinococcus multilocularis PHD finger protein rhinoceros 0.0029 0.0151 0.0147
Echinococcus multilocularis geminin 0.017 0.1854 0.1851
Schistosoma mansoni jumonji domain containing protein 0.0076 0.0718 0.0874
Echinococcus granulosus Niemann Pick C1 protein 0.0102 0.1035 0.1262
Giardia lamblia Fructose-bisphosphate aldolase 0.0293 0.3346 1
Loa Loa (eye worm) hypothetical protein 0.002 0.0042 0.0044
Echinococcus multilocularis lipoxygenase domain containing protein 0.004 0.0275 0.0272
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0066 0.0598 0.0853
Loa Loa (eye worm) hypothetical protein 0.0031 0.0168 0.0228
Echinococcus multilocularis zinc finger protein 0.0034 0.0207 0.0204
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.002 0.0042 0.0047
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0038 0.0261 0.0716
Schistosoma mansoni RAR-like nuclear receptor 0.002 0.0042 0.0047
Echinococcus multilocularis lysine specific demethylase 5A 0.0035 0.0225 0.0222
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.002 0.0042 0.0047
Giardia lamblia Histone acetyltransferase GCN5 0.0157 0.1701 0.4853
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0038 0.0252 0.0523
Trichomonas vaginalis maltase-glucoamylase, putative 0.0038 0.0252 0.0686
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0293 0.3346 1
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0174 0.1899 0.2319
Schistosoma mansoni jumonji/arid domain-containing protein 0.0037 0.0248 0.0299
Loa Loa (eye worm) glucose-6-phosphate dehydrogenase 0.0218 0.2439 0.3528
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.0085 0.0017
Entamoeba histolytica hypothetical protein 0.0073 0.0686 0.1855
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0143 0.153 0.4892
Echinococcus multilocularis microtubule associated protein 2 0.0692 0.8177 0.8176
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0029 0.0153 0.0583
Toxoplasma gondii 6-phosphofructokinase 0.0029 0.0153 0.0559
Loa Loa (eye worm) hypothetical protein 0.002 0.0042 0.0044
Mycobacterium ulcerans hypothetical protein 0.0025 0.0094 0.0265
Echinococcus granulosus transcription factor Dp 1 0.0038 0.0261 0.0314
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0221 0.0595
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.002 0.0042 0.0047
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0293 0.3346 1
Loa Loa (eye worm) jmjC domain-containing protein 0.006 0.0528 0.075
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0038 0.0261 0.0716
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0024 0.0085 0.0552
Echinococcus multilocularis citrate lyase subunit beta protein 0.0025 0.0094 0.009
Loa Loa (eye worm) 6-phosphofructokinase 0.0109 0.1117 0.1606
Brugia malayi serine/threonine-protein kinase plk-2 0.0095 0.0944 0.1316
Brugia malayi Hexokinase family protein 0.0025 0.0098 0.0082
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0044 0.0328 0.046
Echinococcus multilocularis chromobox protein 1 0.007 0.0643 0.0639
Entamoeba histolytica acyl-CoA synthetase, putative 0.0024 0.0085 0.0012
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.003 0.0159 0.0583
Loa Loa (eye worm) hypothetical protein 0.0026 0.0107 0.0138
Toxoplasma gondii NAC domain-containing protein 0.0035 0.0221 0.0828
Leishmania major hexokinase, putative 0.0081 0.0772 0.2931
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0293 0.3346 1
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0023 0.007 0.0082
Echinococcus granulosus FTZ F1 alpha 0.002 0.0042 0.0047
Echinococcus granulosus expressed conserved protein 0.0096 0.096 0.117
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0174 0.1903 0.7482
Schistosoma mansoni hypothetical protein 0.0042 0.0309 0.0374
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.002 0.0042 0.0044
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.002 0.0042 0.0047
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0132 0.0328
Onchocerca volvulus 0.004 0.0275 0.0887
Trypanosoma cruzi hexokinase, putative 0.0081 0.0772 0.289
Loa Loa (eye worm) hypothetical protein 0.002 0.0042 0.0044
Loa Loa (eye worm) hypothetical protein 0.0055 0.0462 0.0654
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0029 0.0153 0.0222
Echinococcus granulosus citrate lyase subunit beta protein 0.0025 0.0094 0.0111
Echinococcus multilocularis hexokinase 0.0081 0.0772 0.0768
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.002 0.0042 0.0038
Echinococcus multilocularis RUN 0.004 0.0275 0.0272
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0038 0.0261 0.0987
Loa Loa (eye worm) hexokinase type II 0.0081 0.0772 0.1105
Schistosoma mansoni hypothetical protein 0.017 0.1854 0.2264
Brugia malayi jmjC domain containing protein 0.0096 0.0956 0.1335
Mycobacterium tuberculosis Conserved protein 0.0025 0.0094 0.0615
Schistosoma mansoni hypothetical protein 0.0029 0.0151 0.018
Onchocerca volvulus 0.0083 0.0806 0.2904
Trypanosoma brucei hexokinase, putative 0.0081 0.0772 0.2931
Entamoeba histolytica hexokinase 1 0.0081 0.0772 0.2117
Echinococcus granulosus jumonji domain containing protein 0.0041 0.0289 0.0349
Loa Loa (eye worm) hypothetical protein 0.0246 0.2772 0.4012
Brugia malayi Glycosyl hydrolases family 31 protein 0.0038 0.0252 0.0306
Echinococcus multilocularis Niemann Pick C1 protein 0.0102 0.1035 0.1032
Echinococcus multilocularis expressed conserved protein 0.0096 0.096 0.0957
Echinococcus granulosus histone lysine methyltransferase setb 0.0047 0.0366 0.0444
Trichomonas vaginalis alpha-glucosidase, putative 0.0038 0.0252 0.0686
Onchocerca volvulus 0.0152 0.1632 0.6041
Trichomonas vaginalis alpha-glucosidase, putative 0.0038 0.0252 0.0686
Trichomonas vaginalis CAMK family protein kinase 0.0047 0.0364 0.1026
Brugia malayi Niemann-Pick C1 protein precursor 0.0102 0.1035 0.145
Trichomonas vaginalis set domain proteins, putative 0.0238 0.2673 0.7975
Trichomonas vaginalis glucosamine-6-phosphate isomerase, putative 0.0227 0.254 0.7573
Schistosoma mansoni hypothetical protein 0.0061 0.0541 0.0657
Mycobacterium ulcerans 6-phosphofructokinase 0.0109 0.1117 0.3559
Onchocerca volvulus Hexokinase homolog 0.0051 0.0408 0.1392
Trichomonas vaginalis CAMK family protein kinase 0.0095 0.0944 0.277
Mycobacterium tuberculosis Probable citrate (pro-3S)-lyase (beta subunit) CitE (citrase) (citratase) (citritase) (citridesmolase) (citrase aldolase) 0.0025 0.0094 0.0615
Schistosoma mansoni patched 1 0.0044 0.0328 0.0397
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0029 0.0146 0.0174
Leishmania major ATP-dependent phosphofructokinase 0.0109 0.1117 0.4393
Brugia malayi MH2 domain containing protein 0.012 0.1246 0.1758
Brugia malayi hypothetical protein 0.004 0.0275 0.0341
Trichomonas vaginalis CAMK family protein kinase 0.0095 0.0944 0.277
Echinococcus granulosus chromobox protein 1 0.007 0.0643 0.0782
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0074 0.0695 0.0691
Schistosoma mansoni hypothetical protein 0.004 0.0275 0.0333
Trypanosoma cruzi transcription factor btf3, putative 0.0035 0.0221 0.0542
Echinococcus granulosus RUN 0.004 0.0275 0.0333
Entamoeba histolytica hexokinase 2 0.0081 0.0772 0.2117
Schistosoma mansoni glutaminase 0.0274 0.3116 0.3808
Brugia malayi PHD-finger family protein 0.0029 0.0151 0.0159
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0066 0.0598 0.2195
Brugia malayi beta-NAC-like protein 0.0035 0.0221 0.0262
Loa Loa (eye worm) hypothetical protein 0.0057 0.0488 0.0692
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0153 0.039
Loa Loa (eye worm) hypothetical protein 0.0024 0.0085 0.0106
Toxoplasma gondii PHD-finger domain-containing protein 0.0029 0.0151 0.0549
Schistosoma mansoni hypothetical protein 0.0021 0.0047 0.0053
Loa Loa (eye worm) 6-phosphofructokinase 0.0109 0.1117 0.1606
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0039 0.0271 0.087
Plasmodium vivax glucose-6-phosphate 1-dehydrogenase, putative 0.0227 0.254 1
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0061 0.0534 0.053
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0095 0.0944 0.366
Giardia lamblia Glucose-6-phosphate 1-dehydrogenase 0.0227 0.254 0.7477
Trypanosoma brucei glucosidase, putative 0.0038 0.0252 0.0725
Plasmodium vivax hexokinase, putative 0.0081 0.0772 0.3006
Trichomonas vaginalis Citrate lyase beta chain, putative 0.0025 0.0094 0.0213
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0024 0.0085 0.0234
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0221 0.0595
Entamoeba histolytica acyl-coA synthetase, putative 0.0024 0.0085 0.0012
Echinococcus granulosus L aminoadipate semialdehyde 0.0083 0.0806 0.0982
Loa Loa (eye worm) hypothetical protein 0.0054 0.0448 0.0634
Trypanosoma brucei polo-like protein kinase 0.0095 0.0944 0.366
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0023 0.0081 0.0272
Echinococcus granulosus hexokinase 0.0081 0.0772 0.094
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.002 0.0042 0.0038
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0328 0.0917
Trypanosoma brucei glucose-6-phosphate 1-dehydrogenase 0.0218 0.2439 1
Mycobacterium ulcerans citrate (pro-3S)-lyase subunit beta 0.0025 0.0094 0.0265
Brugia malayi hypothetical protein 0.0246 0.2772 0.3986
Trypanosoma cruzi transcription factor btf3, putative 0.0035 0.0221 0.0542
Brugia malayi acetyltransferase, GNAT family protein 0.0586 0.6891 1
Schistosoma mansoni jumonji/arid domain-containing protein 0.0037 0.0248 0.0299
Echinococcus multilocularis ecdysone induced protein 78C 0.002 0.0042 0.0038
Schistosoma mansoni Tr4/Tr2 (homologue) 0.002 0.0042 0.0047
Echinococcus multilocularis tumor protein p63 0.0351 0.4048 0.4046
Schistosoma mansoni lipoxygenase 0.0174 0.1899 0.2319
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0029 0.0153 0.056
Echinococcus granulosus zinc finger protein 0.0034 0.0207 0.0249
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0023 0.0081 0.0272
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0061 0.0534 0.3489
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0038 0.0261 1
Brugia malayi glucose-6-phosphate dehydrogenase 0.0218 0.2439 0.3499
Trichomonas vaginalis alpha-glucosidase, putative 0.0038 0.0252 0.0686
Trichomonas vaginalis inositol monophosphatase, putative 0.0038 0.0261 0.0716
Loa Loa (eye worm) hypothetical protein 0.0047 0.0366 0.0515
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0083 0.0806 0.1116
Echinococcus multilocularis FTZ F1 alpha 0.002 0.0042 0.0038
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.002 0.0042 0.0038
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.002 0.0042 0.0044
Echinococcus granulosus nuclear receptor 2DBD gamma 0.002 0.0042 0.0047
Echinococcus multilocularis L aminoadipate semialdehyde 0.0083 0.0806 0.0803
Echinococcus granulosus transcription factor btf3 0.0035 0.0221 0.0266
Treponema pallidum hexokinase (hxk) 0.0081 0.0772 0.2117
Trichomonas vaginalis CAMK family protein kinase 0.0095 0.0944 0.277
Trichomonas vaginalis protein kinase inhibitor, putative 0.0061 0.0541 0.1556
Loa Loa (eye worm) jmjC domain-containing protein 0.0037 0.0248 0.0344
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0038 0.0261 0.0713
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.0085 0.0017
Treponema pallidum fructose-bisphosphate aldolase 0.0293 0.3346 1
Loa Loa (eye worm) steroid hormone receptor 0.002 0.0042 0.0044
Leishmania major basic transcription factor 3a, putative 0.0035 0.0221 0.0596
Schistosoma mansoni retinoic acid receptor RXR 0.002 0.0042 0.0047
Onchocerca volvulus 0.0024 0.0085 0.0161
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0024 0.0085 0.0234
Leishmania major hypothetical protein, conserved 0.0213 0.238 0.975
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0066 0.0598 0.215
Loa Loa (eye worm) hypothetical protein 0.0102 0.1035 0.1488
Toxoplasma gondii phosphofructokinase PFKII 0.0029 0.0153 0.0559
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0109 0.1117 0.4361
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0066 0.0598 0.0727
Echinococcus granulosus glucose 6 phosphate 1 dehydrogenase 0.0218 0.2439 0.298
Echinococcus multilocularis thyroid hormone receptor alpha 0.002 0.0042 0.0038
Schistosoma mansoni survival motor neuron protein 0.005 0.0404 0.0489
Plasmodium vivax multidomain scavenger receptor, putative 0.004 0.0275 0.1043
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0093 0.0928 0.1293
Loa Loa (eye worm) PHD-finger family protein 0.0029 0.0151 0.0202
Trichomonas vaginalis CAMK family protein kinase 0.0095 0.0944 0.277
Trypanosoma cruzi polo-like protein kinase, putative 0.0095 0.0944 0.3623
Echinococcus granulosus lipoxygenase domain containing protein 0.004 0.0275 0.0333
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0036 0.0233 0.0281
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0066 0.0598 0.0595
Trichomonas vaginalis alpha-glucosidase, putative 0.0038 0.0252 0.0686
Echinococcus granulosus neutral alpha glucosidase AB 0.0038 0.0252 0.0303
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0066 0.0598 0.2195
Schistosoma mansoni 6-phosphofructokinase 0.0109 0.1117 0.1362
Echinococcus multilocularis protein patched 0.0044 0.0328 0.0325
Schistosoma mansoni rab6-interacting 0.004 0.0275 0.0333
Schistosoma mansoni hypothetical protein 0.0042 0.0309 0.0374
Trypanosoma cruzi hypothetical protein, conserved 0.0213 0.238 0.9749
Trichomonas vaginalis sucrase-isomaltase, putative 0.0038 0.0252 0.0686
Echinococcus multilocularis peregrin 0.0046 0.0353 0.0349
Schistosoma mansoni coup transcription factor 0.002 0.0042 0.0047
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0047 0.0366 0.0363
Schistosoma mansoni bromodomain containing protein 0.0019 0.0022 0.0022
Chlamydia trachomatis holo [acyl-carrier protein] synthase 0.0023 0.0081 0.0284
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0096 0.0956 0.1165
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0174 0.1899 0.1896
Loa Loa (eye worm) hypothetical protein 0.005 0.0404 0.057
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0018 0.0012 0.0077
Echinococcus multilocularis Polycystic kidney disease protein 0.004 0.0275 0.0272
Loa Loa (eye worm) heterochromatin protein 1 0.007 0.0643 0.0917
Entamoeba histolytica hypothetical protein 0.0035 0.0221 0.0431
Schistosoma mansoni bromodomain containing protein 0.0078 0.0738 0.0899
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0093 0.0928 0.0924
Schistosoma mansoni glucose-6-phosphate 1-dehydrogenase 0.0218 0.2439 0.298
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0586 0.6891 0.689
Schistosoma mansoni nuclear hormone receptor 0.002 0.0042 0.0047
Echinococcus multilocularis survival motor neuron protein 1 0.0246 0.2772 0.2769
Onchocerca volvulus 0.0081 0.0772 0.2773
Onchocerca volvulus 0.0081 0.0772 0.2773
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0085 0.0062
Echinococcus granulosus hexokinase 0.0081 0.0772 0.094
Onchocerca volvulus 0.005 0.0404 0.1374
Echinococcus multilocularis neutral alpha glucosidase AB 0.0038 0.0252 0.0248
Schistosoma mansoni alpha glucosidase 0.0038 0.0252 0.0303
Trypanosoma brucei hypothetical protein, conserved 0.0213 0.238 0.975
Echinococcus multilocularis chromobox protein 1 0.007 0.0643 0.0639
Echinococcus granulosus ecdysone induced protein 78C 0.002 0.0042 0.0047
Trichomonas vaginalis CAMK family protein kinase 0.0095 0.0944 0.277
Schistosoma mansoni 6-phosphofructokinase 0.0109 0.1117 0.1362
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.002 0.0042 0.0044
Trichomonas vaginalis alpha-glucosidase, putative 0.0038 0.0252 0.0686
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0153 0.039
Schistosoma mansoni hexokinase 0.0081 0.0772 0.094
Brugia malayi glutaminase DH11.1 0.0274 0.3116 0.4488
Toxoplasma gondii PHD-finger domain-containing protein 0.0029 0.0151 0.0549
Brugia malayi Pre-SET motif family protein 0.0209 0.2324 0.3332
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.002 0.0042 0.0047
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0024 0.0085 0.0552
Schistosoma mansoni thyroid hormone receptor 0.002 0.0042 0.0047
Plasmodium vivax 6-phosphofructokinase, putative 0.0029 0.0153 0.056
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0038 0.0252 0.0686
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0029 0.0153 0.0559
Toxoplasma gondii aldehyde dehydrogenase 0.0061 0.0534 0.2066
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0095 0.0944 0.1355
Loa Loa (eye worm) phosphofructokinase 0.0109 0.1117 0.1606
Plasmodium falciparum LCCL domain-containing protein 0.004 0.0275 0.1043
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0036 0.0233 0.0229
Trichomonas vaginalis CAMK family protein kinase 0.0095 0.0944 0.277
Onchocerca volvulus Alhambra homolog 0.0029 0.0151 0.0413
Loa Loa (eye worm) hypothetical protein 0.004 0.0275 0.0383
Trypanosoma brucei hexokinase 0.0081 0.0772 0.2931
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.002 0.0042 0.0044
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0085 0.0234
Schistosoma mansoni polycystin 1-related 0.004 0.0275 0.0333
Echinococcus granulosus histone acetyltransferase KAT2B 0.0567 0.6664 0.8149
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.002 0.0042 0.0038
Trypanosoma cruzi hypothetical protein, conserved 0.0038 0.0252 0.0671
Loa Loa (eye worm) MH2 domain-containing protein 0.012 0.1246 0.1795
Brugia malayi chromobox protein homolog 3 0.0039 0.0271 0.0334
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0093 0.0928 0.1331
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0093 0.0928 0.113
Treponema pallidum glucose-6-phosphate 1-dehydrogenase 0.0218 0.2439 0.7222
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.005 0.0404 0.0528
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0047 0.0366 0.0444
Echinococcus multilocularis dnaJ subfamily C 6 0.0061 0.0541 0.0537
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0066 0.0598 0.0812
Echinococcus multilocularis lysosomal alpha glucosidase 0.0169 0.1847 0.1844
Entamoeba histolytica phosphofructokinase, putative 0.0109 0.1117 0.3173
Schistosoma mansoni inositol monophosphatase 0.0038 0.0261 0.0315
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0066 0.0598 0.215
Chlamydia trachomatis glucose-6-phosphate 1-dehydrogenase 0.0218 0.2439 1
Onchocerca volvulus 0.0041 0.0298 0.0971
Toxoplasma gondii glucose-6-phosphate 1-dehydrogenase 0.0227 0.254 1
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0085 0.0062
Echinococcus granulosus lipoxygenase domain containing protein 0.004 0.0275 0.0333
Giardia lamblia Kinase, PLK 0.0095 0.0944 0.2482
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0153 0.039
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0293 0.3346 1
Trichomonas vaginalis chromobox protein, putative 0.0042 0.0307 0.0853
Loa Loa (eye worm) hypothetical protein 0.0024 0.0085 0.0106
Leishmania major 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0025 0.0094 0.0057
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0109 0.1117 0.3173
Trypanosoma cruzi glucose-6-phosphate 1-dehydrogenase, putative 0.0072 0.0672 0.2465
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0038 0.0252 0.0948
Brugia malayi Bromodomain containing protein 0.0053 0.0435 0.0573
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0047 0.0366 0.0444
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0093 0.0928 0.113
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0066 0.0598 0.1585
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0023 0.0081 0.0272
Loa Loa (eye worm) glutaminase 0.0274 0.3116 0.4513
Loa Loa (eye worm) ICD-1 protein 0.0035 0.0221 0.0304
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0038 0.0261 0.0767
Echinococcus multilocularis lipoxygenase domain containing protein 0.004 0.0275 0.0272
Schistosoma mansoni aldehyde dehydrogenase 0.0061 0.0534 0.0649
Plasmodium vivax SET domain protein, putative 0.003 0.0159 0.0583
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0073 0.0686 0.0683
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0095 0.0944 0.094
Echinococcus granulosus fetal alzheimer antigen falz 0.0023 0.007 0.0082
Echinococcus multilocularis hexokinase type 2 0.0081 0.0772 0.0768
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0209 0.2324 0.3361
Trypanosoma cruzi Glucose-6-phosphate dehydrogenase, putative 0.007 0.0647 0.2357
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0024 0.0085 0.0234
Loa Loa (eye worm) inositol-1 0.0038 0.0261 0.0363

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

If you have references for this compound, please enter them in a user comment (below) or Contact us.