Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | CAMK family protein kinase | 0.0086 | 0.4054 | 1 |
Echinococcus granulosus | fetal alzheimer antigen falz | 0.0021 | 0.0169 | 0.0207 |
Brugia malayi | Bromodomain containing protein | 0.0036 | 0.1063 | 0.0784 |
Trypanosoma cruzi | polo-like protein kinase, putative | 0.0086 | 0.4054 | 0.5 |
Echinococcus granulosus | serine:threonine protein kinase PLK1 | 0.0086 | 0.4054 | 0.4982 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0034 | 0.0929 | 0.1142 |
Schistosoma mansoni | hypothetical protein | 0.0031 | 0.0752 | 0.1855 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.131 | 0.1258 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0056 | 0.2279 | 0.28 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0086 | 0.4054 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0067 | 0.2904 | 0.2862 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0045 | 0.1614 | 0.1352 |
Trypanosoma brucei | polo-like protein kinase | 0.0086 | 0.4054 | 0.5 |
Schistosoma mansoni | acetyl-CoA C-acetyltransferase | 0.0021 | 0.0169 | 0.0416 |
Echinococcus multilocularis | fetal alzheimer antigen, falz | 0.0021 | 0.0169 | 0.0207 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0086 | 0.4054 | 1 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0086 | 0.4054 | 1 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0034 | 0.0929 | 0.1142 |
Loa Loa (eye worm) | hypothetical protein | 0.0184 | 1 | 1 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0031 | 0.0752 | 0.0463 |
Trypanosoma cruzi | polo-like protein kinase, putative | 0.0086 | 0.4054 | 0.5 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0154 | 0.8137 | 1 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0086 | 0.4054 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0752 | 0.0696 |
Brugia malayi | Bromodomain containing protein | 0.0071 | 0.3147 | 0.2933 |
Schistosoma mansoni | bromodomain containing protein | 0.006 | 0.2482 | 0.6123 |
Giardia lamblia | Kinase, PLK | 0.0086 | 0.4054 | 0.5 |
Leishmania major | protein kinase, putative,polo-like protein kinase, putative | 0.0086 | 0.4054 | 0.5 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0086 | 0.4054 | 1 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0056 | 0.2279 | 0.28 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0045 | 0.1614 | 0.1564 |
Schistosoma mansoni | hypothetical protein | 0.0019 | 0.006 | 0.0148 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0154 | 0.8137 | 1 |
Loa Loa (eye worm) | PLK/PLK1 protein kinase | 0.0086 | 0.4054 | 0.4018 |
Echinococcus multilocularis | serine:threonine protein kinase PLK1 | 0.0086 | 0.4054 | 0.4982 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0086 | 0.4054 | 1 |
Entamoeba histolytica | serine/threonine protein kinase, putative | 0.0086 | 0.4054 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.1067 | 0.1013 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0086 | 0.4054 | 1 |
Schistosoma mansoni | kinase | 0.0044 | 0.1513 | 0.3734 |
Onchocerca volvulus | Serine\/threonine kinase homolog | 0.0086 | 0.4054 | 0.5 |
Brugia malayi | serine/threonine-protein kinase plk-2 | 0.0086 | 0.4054 | 0.3868 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.1202 | 0.1149 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.