Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0.0525 | 0.1969 |
Treponema pallidum | exodeoxyribonuclease (exoA) | 0.0022 | 0.2667 | 1 |
Mycobacterium ulcerans | exodeoxyribonuclease III protein XthA | 0.0022 | 0.2667 | 0.5 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0.0525 | 0.1969 |
Echinococcus granulosus | DNA apurinic or apyrimidinic site lyase | 0.0022 | 0.2667 | 0.5651 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.0008 | 0.0634 | 0.1257 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.001 | 0.0939 | 0.1916 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0.0525 | 0.1969 |
Trichomonas vaginalis | carbon catabolite repressor protein, putative | 0.0004 | 0.0053 | 0.0199 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0525 | 0.1969 |
Trichomonas vaginalis | carbon catabolite repressor protein, putative | 0.0004 | 0.0053 | 0.0199 |
Echinococcus granulosus | mixed lineage leukemia protein mll | 0.0008 | 0.0634 | 0.1257 |
Leishmania major | apurinic/apyrimidinic endonuclease-redox protein | 0.0022 | 0.2667 | 1 |
Loa Loa (eye worm) | histone methyltransferase | 0.001 | 0.0939 | 0.2042 |
Echinococcus multilocularis | DNA (apurinic or apyrimidinic site) lyase | 0.0022 | 0.2667 | 0.5651 |
Schistosoma mansoni | cpg binding protein | 0.0035 | 0.4678 | 0.465 |
Trichomonas vaginalis | sphingomyelinase C 2 precursor, putative | 0.0004 | 0.0053 | 0.0199 |
Schistosoma mansoni | cpg binding protein | 0.0033 | 0.4393 | 0.4363 |
Trichomonas vaginalis | ap endonuclease, putative | 0.0022 | 0.2667 | 1 |
Brugia malayi | F/Y-rich N-terminus family protein | 0.001 | 0.092 | 0.1996 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0525 | 0.1969 |
Trichomonas vaginalis | skeletal muscle/kidney enriched inositol 5-phosphatase, putative | 0.0004 | 0.0053 | 0.0199 |
Echinococcus multilocularis | mixed lineage leukemia protein mll | 0.0008 | 0.0634 | 0.1257 |
Trichomonas vaginalis | chromodomain-helicase-DNA-binding protein, putative | 0.0007 | 0.0525 | 0.1969 |
Giardia lamblia | Endonuclease/Exonuclease/phosphatase | 0.0022 | 0.2667 | 1 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease | 0.0022 | 0.2667 | 1 |
Trichomonas vaginalis | carbon catabolite repressor protein, putative | 0.0004 | 0.0053 | 0.0199 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0.0525 | 0.1969 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0525 | 0.1969 |
Schistosoma mansoni | cpg binding protein | 0.0035 | 0.4678 | 0.465 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0525 | 0.1969 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0525 | 0.1969 |
Trichomonas vaginalis | ocrl type II inositol 5-phosphatase, putative | 0.0004 | 0.0053 | 0.0199 |
Mycobacterium tuberculosis | Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) | 0.0022 | 0.2667 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0525 | 0.1969 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.0008 | 0.0634 | 0.1257 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0005 | 0.0109 | 0.0056 |
Schistosoma mansoni | ap endonuclease | 0.0022 | 0.2667 | 0.2628 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0.0525 | 0.1969 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0008 | 0.0634 | 0.0584 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.0033 | 0.4393 | 1 |
Trichomonas vaginalis | ap endonuclease, putative | 0.0022 | 0.2667 | 1 |
Trichomonas vaginalis | type IV inositol 5-phosphatase, putative | 0.0004 | 0.0053 | 0.0199 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0525 | 0.1969 |
Echinococcus multilocularis | cpg binding protein | 0.0035 | 0.4678 | 1 |
Onchocerca volvulus | 0.0033 | 0.4393 | 1 | |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.0063 | 0.8867 | 1 |
Plasmodium falciparum | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0022 | 0.2667 | 1 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease, putative | 0.0022 | 0.2667 | 1 |
Trichomonas vaginalis | type II inositol 5-phosphatase, putative | 0.0004 | 0.0053 | 0.0199 |
Trypanosoma brucei | apurinic/apyrimidinic endonuclease, putative | 0.0022 | 0.2667 | 1 |
Echinococcus granulosus | cpg binding protein | 0.0035 | 0.4678 | 1 |
Trichomonas vaginalis | Phospholipase C precursor, putative | 0.0004 | 0.0053 | 0.0199 |
Plasmodium vivax | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0022 | 0.2667 | 1 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0.0525 | 0.1969 |
Brugia malayi | CXXC zinc finger family protein | 0.0033 | 0.4393 | 1 |
Wolbachia endosymbiont of Brugia malayi | exonuclease III | 0.0022 | 0.2667 | 0.5 |
Trichomonas vaginalis | helicase, putative | 0.0007 | 0.0525 | 0.1969 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0525 | 0.1969 |
Entamoeba histolytica | exodeoxyribonuclease III, putative | 0.0022 | 0.2667 | 1 |
Toxoplasma gondii | exonuclease III APE | 0.0022 | 0.2667 | 0.2966 |
Brugia malayi | exodeoxyribonuclease III family protein | 0.0022 | 0.2667 | 0.6023 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.001 | 0.0939 | 0.1916 |
Loa Loa (eye worm) | exodeoxyribonuclease III family protein | 0.0022 | 0.2667 | 0.6023 |
Schistosoma mansoni | ap endonuclease | 0.0022 | 0.2667 | 0.2628 |
Trichomonas vaginalis | chromodomain-helicase-DNA-binding protein, putative | 0.0007 | 0.0525 | 0.1969 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0525 | 0.1969 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.