Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0048 | 0.312 | 0.6053 |
Schistosoma mansoni | tar DNA-binding protein | 0.0062 | 0.5155 | 0.7321 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0034 | 0.0925 | 0.1313 |
Echinococcus multilocularis | tar DNA binding protein | 0.0062 | 0.5155 | 0.5155 |
Echinococcus multilocularis | jumonji domain containing protein | 0.0039 | 0.1721 | 0.1721 |
Loa Loa (eye worm) | RNA binding protein | 0.0062 | 0.5155 | 1 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0062 | 0.5155 | 0.5155 |
Giardia lamblia | PHD finger protein 15 | 0.0028 | 0 | 0.5 |
Echinococcus multilocularis | lysine specific demethylase 5A | 0.0034 | 0.0925 | 0.0925 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0034 | 0.0925 | 0.1794 |
Brugia malayi | jmjC domain containing protein | 0.0034 | 0.0925 | 0.0925 |
Echinococcus multilocularis | Transcription factor, JmjC domain containing protein | 0.0093 | 1 | 1 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0034 | 0.0925 | 0.1313 |
Plasmodium falciparum | phd finger protein, putative | 0.0028 | 0 | 0.5 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0048 | 0.312 | 0.312 |
Schistosoma mansoni | tar DNA-binding protein | 0.0062 | 0.5155 | 0.7321 |
Schistosoma mansoni | hypothetical protein | 0.0033 | 0.0742 | 0.1054 |
Echinococcus granulosus | lysine specific demethylase 5A | 0.0034 | 0.0925 | 0.0925 |
Brugia malayi | TAR-binding protein | 0.0062 | 0.5155 | 0.5155 |
Loa Loa (eye worm) | hypothetical protein | 0.0048 | 0.312 | 0.6053 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.314 | 0.6092 |
Schistosoma mansoni | tar DNA-binding protein | 0.0062 | 0.5155 | 0.7321 |
Schistosoma mansoni | tar DNA-binding protein | 0.0062 | 0.5155 | 0.7321 |
Loa Loa (eye worm) | TAR-binding protein | 0.0062 | 0.5155 | 1 |
Echinococcus granulosus | Transcription factor JmjC domain containing protein | 0.0093 | 1 | 1 |
Toxoplasma gondii | PHD-finger domain-containing protein | 0.0028 | 0 | 0.5 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0033 | 0.0742 | 0.0742 |
Schistosoma mansoni | jumonji domain containing protein | 0.0074 | 0.7041 | 1 |
Echinococcus granulosus | jumonji domain containing protein | 0.0039 | 0.1721 | 0.1721 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0742 | 0.144 |
Brugia malayi | RNA binding protein | 0.0062 | 0.5155 | 0.5155 |
Echinococcus granulosus | tar DNA binding protein | 0.0062 | 0.5155 | 0.5155 |
Toxoplasma gondii | PHD-finger domain-containing protein | 0.0028 | 0 | 0.5 |
Plasmodium vivax | hypothetical protein, conserved | 0.0028 | 0 | 0.5 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0062 | 0.5155 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0062 | 0.5155 | 0.7321 |
Onchocerca volvulus | Alhambra homolog | 0.0028 | 0 | 0.5 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0048 | 0.312 | 0.312 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0058 | 0.468 | 0.9079 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.