Detailed information for compound 729378

Basic information

Technical information
  • TDR Targets ID: 729378
  • Name: 4-(methoxymethyl)-N-(pyridin-4-ylmethyl)benza mide
  • MW: 256.3 | Formula: C15H16N2O2
  • H donors: 1 H acceptors: 2 LogP: 1.27 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 1
  • SMILES: COCc1ccc(cc1)C(=O)NCc1ccncc1
  • InChi: 1S/C15H16N2O2/c1-19-11-13-2-4-14(5-3-13)15(18)17-10-12-6-8-16-9-7-12/h2-9H,10-11H2,1H3,(H,17,18)
  • InChiKey: JJBILHFZLQMNCR-UHFFFAOYSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

  • 4-(methoxymethyl)-N-(4-pyridylmethyl)benzamide
  • 4-Methoxymethyl-N-pyridin-4-ylmethyl-benzamide
  • ASN 14482854
  • ZINC04999222

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus granulosus endoplasmin 0.0027 0.0193 0.0193
Echinococcus multilocularis microtubule associated protein 2 0.0719 1 1
Leishmania major lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative 0.0027 0.0193 0.1555
Leishmania major heat shock protein 83-1 0.0034 0.0292 0.2374
Schistosoma mansoni ran 0.0022 0.0124 0.0118
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0016 0.0041 0.0041
Trichomonas vaginalis heat shock protein, putative 0.0027 0.0193 0.0566
Echinococcus multilocularis snurportin 1 0.0324 0.4393 0.4393
Loa Loa (eye worm) PHD-finger family protein 0.0061 0.0673 0.105
Trichomonas vaginalis ap endonuclease, putative 0.002 0.0086 0.024
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0015 0.0021 0.0045
Echinococcus granulosus lysine specific demethylase 6a 0.002 0.0087 0.0087
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0054 0.0571 0.7143
Loa Loa (eye worm) hypothetical protein 0.0049 0.0498 0.0777
Echinococcus granulosus mitogen activated protein kinase 3 0.0054 0.0571 0.0571
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0022 0.0124 0.1488
Brugia malayi AF-10 protein 0.002 0.009 0.0139
Brugia malayi Calcitonin receptor-like protein seb-1 0.0052 0.0544 0.0847
Trichomonas vaginalis CMGC family protein kinase 0.0054 0.0571 0.1708
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.002 0.009 0.07
Trichomonas vaginalis set domain proteins, putative 0.0248 0.3316 1
Echinococcus multilocularis kelch ECH associated protein 1 0.0098 0.1203 0.1203
Trypanosoma cruzi ISWI complex protein 0.0032 0.0262 0.2122
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0015 0.0021 0.0033
Echinococcus granulosus pyruvate kinase 0.0036 0.0316 0.0316
Loa Loa (eye worm) hypothetical protein 0.0038 0.034 0.053
Wolbachia endosymbiont of Brugia malayi heat shock protein 90 0.0027 0.0193 1
Trypanosoma brucei importin beta-1 subunit, putative 0.003 0.0237 0.192
Trichomonas vaginalis esterase, putative 0.0038 0.034 0.1007
Loa Loa (eye worm) hypothetical protein 0.0061 0.0673 0.105
Brugia malayi Pyruvate kinase, muscle isozyme 0.007 0.0797 0.1242
Giardia lamblia Heat shock protein HSP 90-alpha 0.0034 0.0292 0.1836
Schistosoma mansoni hypothetical protein 0.0611 0.8466 0.8465
Echinococcus multilocularis tumor susceptibility gene 101 protein 0.0072 0.0835 0.0835
Trypanosoma brucei protein kinase, putative 0.0054 0.0571 0.4696
Loa Loa (eye worm) CXXC zinc finger family protein 0.003 0.0236 0.0368
Brugia malayi beta-lactamase 0.0038 0.034 0.0527
Toxoplasma gondii PHD-finger domain-containing protein 0.0061 0.0673 0.8424
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0038 0.034 0.0312
Schistosoma mansoni heat shock protein 0.0034 0.0292 0.0286
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0022 0.0124 0.0193
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0069 0.0783 0.1222
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0032 0.0258 0.0252
Echinococcus granulosus zinc finger protein 0.0043 0.0413 0.0413
Brugia malayi Endoplasmin precursor 0.0034 0.0292 0.0453
Mycobacterium tuberculosis Probable esterase LipL 0.0038 0.034 0.0312
Loa Loa (eye worm) hypothetical protein 0.0026 0.0172 0.0268
Schistosoma mansoni chromobox protein 0.0073 0.0837 0.0831
Trypanosoma brucei Vps23 core domain containing protein, putative 0.0023 0.0136 0.1081
Trichomonas vaginalis CAMK family protein kinase 0.0049 0.0505 0.1508
Echinococcus granulosus pyruvate kinase 0.0036 0.0316 0.0316
Echinococcus multilocularis pyruvate kinase 0.0036 0.0316 0.0316
Mycobacterium ulcerans lipase LipD 0.0038 0.034 0.0312
Brugia malayi intermediate filament protein 0.0028 0.0206 0.0319
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0016 0.0041 0.0041
Echinococcus granulosus heat shock protein 75 kDa mitochondrial 0.0014 0.0006 0.0006
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0022 0.0124 0.1488
Brugia malayi hypothetical protein 0.0027 0.0183 0.0283
Trichomonas vaginalis pyruvate kinase, putative 0.007 0.0797 0.2391
Echinococcus multilocularis pyruvate kinase 0.0055 0.0589 0.0589
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0069 0.0783 0.0783
Loa Loa (eye worm) hypothetical protein 0.0041 0.0385 0.06
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0216 0.0635
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.003 0.0232 0.0232
Mycobacterium ulcerans beta-lactamase 0.0038 0.034 0.0312
Trichomonas vaginalis heat shock protein, putative 0.0034 0.0292 0.0864
Leishmania major heat shock protein 83-1 0.0034 0.0292 0.2374
Echinococcus multilocularis Protein lozenge 0.0058 0.0635 0.0635
Trypanosoma brucei polo-like protein kinase 0.0099 0.121 1
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0054 0.0571 0.0892
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0069 0.0783 0.6452
Entamoeba histolytica hypothetical protein 0.0038 0.0339 0.2766
Brugia malayi beta-lactamase family protein 0.0038 0.034 0.0527
Schistosoma mansoni sex comb on midleg homolog 0.01 0.1223 0.1217
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0069 0.0783 0.0777
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.002 0.0087 0.0671
Loa Loa (eye worm) endoplasmin 0.0034 0.0292 0.0456
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0048 0.0483 0.0752
Schistosoma mansoni methyl-cpg binding protein mbd 0.0036 0.0314 0.0308
Trichomonas vaginalis chromobox protein, putative 0.0073 0.0837 0.251
Schistosoma mansoni ap endonuclease 0.002 0.0086 0.0079
Loa Loa (eye worm) intermediate filament protein 0.0028 0.0206 0.0322
Leishmania major heat shock protein 83-1 0.0034 0.0292 0.2374
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0032 0.0258 0.3183
Toxoplasma gondii pyruvate kinase PyK1 0.007 0.0797 1
Trichomonas vaginalis CAMK family protein kinase 0.0099 0.121 0.3637
Loa Loa (eye worm) hypothetical protein 0.0247 0.33 0.5152
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0385 0.1143
Brugia malayi Latrophilin receptor protein 2 0.0016 0.0041 0.0061
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0041 0.0385 0.0591
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0022 0.0124 0.0978
Loa Loa (eye worm) jmjC domain-containing protein 0.008 0.0936 0.1461
Leishmania major GTP-binding protein, putative 0.0022 0.0124 0.0978
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0018 0.0057 0.0057
Loa Loa (eye worm) CHromoDomain protein family member 0.0018 0.0057 0.0089
Schistosoma mansoni serine/threonine protein kinase 0.0054 0.0571 0.0566
Mycobacterium tuberculosis Probable pyruvate kinase PykA 0.007 0.0797 0.0875
Echinococcus granulosus jumonji domain containing 1A 0.002 0.0087 0.0087
Trypanosoma brucei PAB1-binding protein , putative 0.0027 0.0183 0.1471
Trypanosoma cruzi heat shock protein 85, putative 0.0034 0.0292 0.2374
Onchocerca volvulus Pyruvate kinase homolog 0.007 0.0797 0.1236
Echinococcus granulosus peregrin 0.0066 0.0743 0.0743
Brugia malayi PHD-finger family protein 0.0061 0.0673 0.1048
Plasmodium falciparum importin beta, putative 0.003 0.0237 0.2921
Schistosoma mansoni ap endonuclease 0.002 0.0086 0.0079
Plasmodium falciparum endoplasmin, putative 0.0021 0.0105 0.1246
Schistosoma mansoni endoplasmin 0.0034 0.0292 0.0286
Schistosoma mansoni cpg binding protein 0.0036 0.0317 0.0311
Schistosoma mansoni survival motor neuron protein 0.005 0.052 0.0514
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0022 0.0124 0.0341
Loa Loa (eye worm) pyruvate kinase-PB 0.0049 0.0498 0.0777
Loa Loa (eye worm) pyruvate kinase 0.0015 0.0016 0.0025
Echinococcus granulosus kelch ECH associated protein 1 0.0098 0.1203 0.1203
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0025 0.0168 0.0168
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0038 0.034 0.0334
Trypanosoma cruzi ISWI complex protein 0.0032 0.0262 0.2122
Mycobacterium tuberculosis Conserved protein 0.0038 0.034 0.0312
Plasmodium falciparum ataxin-2 like protein, putative 0.0027 0.0183 0.2238
Trypanosoma cruzi heat shock protein 85, putative 0.0034 0.0292 0.2374
Trichomonas vaginalis D-aminoacylase, putative 0.0038 0.034 0.1007
Trypanosoma cruzi importin beta-1 subunit, putative 0.0025 0.0156 0.1246
Loa Loa (eye worm) PHD-finger family protein 0.0043 0.042 0.0655
Trypanosoma brucei heat shock protein, putative 0.0034 0.0292 0.2374
Echinococcus multilocularis cpg binding protein 0.0036 0.0317 0.0317
Giardia lamblia Pyruvate kinase 0.007 0.0797 0.6332
Onchocerca volvulus 0.003 0.0236 0.0358
Trypanosoma cruzi Vps23 core domain containing protein, putative 0.0023 0.0136 0.1081
Onchocerca volvulus 0.0248 0.3316 0.5171
Brugia malayi cytoplasmic intermediate filament protein 0.0015 0.0021 0.003
Echinococcus multilocularis heat shock protein 75 kDa, mitochondrial 0.0014 0.0006 0.0006
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0025 0.0156 0.0453
Trypanosoma cruzi heat shock protein 90, putative 0.002 0.0094 0.0726
Loa Loa (eye worm) mbt repeat family protein 0.01 0.1223 0.1909
Brugia malayi Bromodomain containing protein 0.0159 0.2057 0.3209
Brugia malayi Pyruvate kinase, M2 isozyme 0.007 0.0797 0.1242
Loa Loa (eye worm) beta-lactamase 0.0038 0.034 0.053
Schistosoma mansoni serine/threonine protein kinase 0.0099 0.121 0.1204
Trypanosoma cruzi pyruvate kinase 2, putative 0.007 0.0797 0.6574
Echinococcus granulosus methyl CpG binding domain protein 2 0.0036 0.0314 0.0314
Trypanosoma brucei ISWI complex protein 0.0032 0.0262 0.2122
Brugia malayi heat shock protein 90 0.0034 0.0292 0.0453
Toxoplasma gondii histone lysine demethylase JMJD6a 0.002 0.0087 0.1021
Trypanosoma brucei heat shock protein 90, putative 0.0034 0.0292 0.2374
Loa Loa (eye worm) hypothetical protein 0.0027 0.0183 0.0286
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0069 0.0783 0.6452
Schistosoma mansoni hypothetical protein 0.0061 0.0673 0.0667
Trypanosoma brucei heat shock protein, putative 0.0034 0.0292 0.2374
Schistosoma mansoni jumonji domain containing protein 0.0159 0.2058 0.2053
Leishmania major pyruvate kinase 0.007 0.0797 0.6574
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0216 0.0635
Entamoeba histolytica Ran family GTPase 0.0022 0.0124 0.0978
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0054 0.0571 0.4696
Mycobacterium leprae Probable pyruvate kinase PykA 0.007 0.0797 0.0752
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0099 0.121 0.121
Echinococcus multilocularis beta LACTamase domain containing family member 0.0038 0.034 0.034
Trichomonas vaginalis ap endonuclease, putative 0.002 0.0086 0.024
Echinococcus granulosus snurportin 1 0.0324 0.4393 0.4393
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0067 0.0764 0.0758
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0065 0.0731 0.0726
Schistosoma mansoni kinase 0.0051 0.0524 0.0518
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.002 0.0086 0.1003
Trypanosoma brucei pyruvate kinase 1, putative 0.007 0.0797 0.6574
Loa Loa (eye worm) runx1 0.0058 0.0635 0.0992
Brugia malayi MAP kinase sur-1 0.0054 0.0571 0.0889
Loa Loa (eye worm) hypothetical protein 0.0038 0.034 0.053
Echinococcus multilocularis chromobox protein 1 0.0073 0.0837 0.0837
Echinococcus granulosus cpg binding protein 0.0036 0.0317 0.0317
Mycobacterium leprae Probable lipase LipE 0.0038 0.034 0.0182
Entamoeba histolytica hypothetical protein 0.0025 0.0156 0.1246
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0025 0.0156 0.0453
Mycobacterium tuberculosis Conserved protein 0.0038 0.034 0.0312
Leishmania major heat shock protein 83-1 0.0034 0.0292 0.2374
Schistosoma mansoni phd/f-box containing protein 0.002 0.0087 0.0081
Echinococcus multilocularis mitogen activated protein kinase 0.0054 0.0571 0.0571
Echinococcus granulosus histone lysine methyltransferase setb 0.0067 0.0764 0.0764
Echinococcus granulosus kelch ECH associated protein 1 like 0.0098 0.1203 0.1203
Leishmania major pyruvate kinase 0.007 0.0797 0.6574
Trichomonas vaginalis penicillin-binding protein, putative 0.0038 0.034 0.1007
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0054 0.0571 0.4696
Trypanosoma brucei pyruvate kinase 1 0.007 0.0797 0.6574
Trypanosoma cruzi hypothetical protein, conserved 0.0038 0.034 0.277
Loa Loa (eye worm) jmjC domain-containing protein 0.002 0.0087 0.0136
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0324 0.4393 0.6858
Leishmania major heat shock protein 83-1 0.0034 0.0292 0.2374
Echinococcus multilocularis GPCR, family 2 0.0016 0.0041 0.0041
Giardia lamblia Heat shock protein HSP 90-alpha 0.0027 0.0193 0.0959
Echinococcus granulosus tumor susceptibility gene 101 protein 0.0072 0.0835 0.0835
Schistosoma mansoni microtubule-associated protein tau 0.0719 1 1
Treponema pallidum heat shock protein 90 0.0027 0.0193 1
Echinococcus granulosus lamin 0.0028 0.0206 0.0206
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0049 0.0501 0.0495
Loa Loa (eye worm) hypothetical protein 0.0036 0.0311 0.0486
Trichomonas vaginalis hypothetical protein 0.0035 0.0308 0.0912
Echinococcus multilocularis lamin 0.0028 0.0206 0.0206
Mycobacterium leprae conserved hypothetical protein 0.0038 0.034 0.0182
Trichomonas vaginalis D-aminoacylase, putative 0.0038 0.034 0.1007
Echinococcus multilocularis PHD finger protein rhinoceros 0.0061 0.0673 0.0673
Echinococcus granulosus lamin dm0 0.0028 0.0206 0.0206
Brugia malayi hypothetical protein 0.0017 0.005 0.0076
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0048 0.0483 0.0483
Echinococcus granulosus JmjC domain containing protein 4 0.002 0.0087 0.0087
Trypanosoma cruzi PAB1-binding protein , putative 0.0027 0.0183 0.1471
Trypanosoma brucei heat shock protein 90, putative 0.0034 0.0292 0.2374
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0048 0.0483 0.0483
Schistosoma mansoni hypothetical protein 0.043 0.5901 0.5898
Trichomonas vaginalis heat shock protein, putative 0.0021 0.0105 0.0298
Plasmodium vivax pyruvate kinase, putative 0.007 0.0797 1
Trypanosoma brucei Heat shock protein 83, putative 0.0034 0.0292 0.2374
Brugia malayi jmjC domain containing protein 0.002 0.0087 0.0133
Echinococcus multilocularis jumonji domain containing protein 0.0085 0.1011 0.1011
Brugia malayi jmjC domain containing protein 0.02 0.2641 0.412
Leishmania major heat shock protein 83-1 0.0034 0.0292 0.2374
Schistosoma mansoni hypothetical protein 0.0099 0.1207 0.1201
Loa Loa (eye worm) hypothetical protein 0.0114 0.1419 0.2215
Onchocerca volvulus 0.0038 0.034 0.0521
Plasmodium vivax pyruvate kinase 2, putative 0.0036 0.0316 0.3912
Trichomonas vaginalis importin beta-1, putative 0.0025 0.0156 0.0453
Loa Loa (eye worm) jmjC domain-containing protein 0.002 0.0087 0.0136
Onchocerca volvulus 0.0038 0.034 0.0521
Schistosoma mansoni hypothetical protein 0.0036 0.0311 0.0305
Leishmania major heat shock protein 83-1 0.0034 0.0292 0.2374
Echinococcus multilocularis pyruvate kinase 0.007 0.0797 0.0797
Echinococcus multilocularis phd:f box containing protein 0.002 0.0087 0.0087
Echinococcus granulosus PHD finger protein rhinoceros 0.0061 0.0673 0.0673
Schistosoma mansoni transcription factor LCR-F1 0.0038 0.0339 0.0333
Entamoeba histolytica exodeoxyribonuclease III, putative 0.002 0.0086 0.0659
Loa Loa (eye worm) hypothetical protein 0.0038 0.034 0.053
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.002 0.0086 0.1003
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0099 0.121 0.121
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.0073 0.0202
Mycobacterium tuberculosis Probable chaperone protein HtpG (heat shock protein) (HSP90 family protein) (high temperature protein G) 0.0027 0.0193 0.0133
Mycobacterium tuberculosis Possible penicillin-binding protein 0.024 0.3205 0.3835
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.002 0.0087 0.0081
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0048 0.0483 0.0477
Echinococcus granulosus intermediate filament protein 0.0028 0.0206 0.0206
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.002 0.0086 0.0659
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.01 0.1223 0.1901
Echinococcus multilocularis lysine specific demethylase 5A 0.0074 0.0855 0.0855
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0048 0.0483 0.0755
Echinococcus multilocularis jumonji domain containing 1A 0.002 0.0087 0.0087
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0038 0.034 0.0312
Giardia lamblia PHD finger protein 15 0.0061 0.0673 0.5222
Schistosoma mansoni zinc finger protein 0.0043 0.0413 0.0407
Onchocerca volvulus 0.0038 0.034 0.0521
Entamoeba histolytica heat shock protein 90, putative 0.0034 0.0292 0.2374
Echinococcus granulosus pyruvate kinase 0.0036 0.0316 0.0316
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0016 0.0041 0.0041
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.02 0.2641 0.2641
Echinococcus granulosus geminin 0.0355 0.4835 0.4835
Echinococcus granulosus histone acetyltransferase MYST2 0.0114 0.1419 0.1419
Leishmania major hypothetical protein, conserved 0.0032 0.0262 0.2122
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.0073 0.0202
Trichomonas vaginalis pyruvate kinase, putative 0.007 0.0797 0.2391
Trichomonas vaginalis CMGC family protein kinase 0.0054 0.0571 0.1708
Mycobacterium leprae Probable UDP-galactopyranose mutase Glf (UDP-galp mutase) (NAD+-flavin adenine dinucleotide-requiring enzyme) 0.0594 0.8221 1
Brugia malayi PHD-finger family protein 0.0026 0.0172 0.0265
Trypanosoma brucei heat shock protein, putative 0.0034 0.0292 0.2374
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0054 0.0571 0.4696
Loa Loa (eye worm) pyruvate kinase 0.007 0.0797 0.1245
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0044 0.0426 0.0421
Schistosoma mansoni cpg binding protein 0.003 0.0236 0.023
Brugia malayi chromobox protein homolog 3 0.0041 0.0385 0.0598
Loa Loa (eye worm) hypothetical protein 0.0038 0.034 0.053
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0069 0.0783 0.1219
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.002 0.0086 0.0659
Plasmodium vivax heat shock protein 86, putative 0.0034 0.0292 0.3612
Echinococcus granulosus chromobox protein 1 0.0073 0.0837 0.0837
Echinococcus multilocularis lamin dm0 0.0028 0.0206 0.0206
Schistosoma mansoni ran 0.0022 0.0124 0.0118
Loa Loa (eye worm) MBCTL1 0.0114 0.1419 0.2215
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0038 0.034 0.053
Loa Loa (eye worm) jmjC domain-containing protein 0.002 0.0087 0.0136
Loa Loa (eye worm) hypothetical protein 0.0038 0.034 0.053
Onchocerca volvulus 0.0028 0.0206 0.0312
Leishmania major heat shock protein 83-1 0.0034 0.0292 0.2374
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0398 0.544 0.544
Plasmodium vivax JmjC domain containing protein 0.002 0.0087 0.1021
Mycobacterium ulcerans pyruvate kinase 0.007 0.0797 0.0875
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0069 0.0783 0.6452
Schistosoma mansoni jumonji domain containing protein 0.002 0.0087 0.0081
Mycobacterium ulcerans heat shock protein 90 0.0027 0.0193 0.0133
Plasmodium vivax hypothetical protein, conserved 0.0038 0.034 0.4213
Trypanosoma brucei importin beta-1 subunit, putative 0.003 0.0237 0.192
Echinococcus multilocularis SAM and MBT domain containing protein 0.01 0.1223 0.1223
Schistosoma mansoni jumonji/arid domain-containing protein 0.008 0.0936 0.093
Schistosoma mansoni hypothetical protein 0.0032 0.0262 0.0256
Brugia malayi jmjC domain containing protein 0.002 0.0087 0.0133
Leishmania major hypothetical protein, conserved 0.0027 0.0183 0.1471
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0114 0.1419 0.1419
Trichomonas vaginalis chromobox protein, putative 0.0044 0.0428 0.1276
Loa Loa (eye worm) hypothetical protein 0.002 0.0087 0.0136
Brugia malayi pyruvate kinase, muscle isozyme 0.0015 0.0016 0.0023
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0038 0.034 0.0527
Onchocerca volvulus Serine\/threonine kinase homolog 0.0099 0.121 0.1881
Plasmodium vivax ataxin-2 like protein, putative 0.0027 0.0183 0.2238
Schistosoma mansoni lozenge 0.0058 0.0635 0.063
Loa Loa (eye worm) hypothetical protein 0.0466 0.6406 1
Trypanosoma brucei heat shock protein, putative 0.0034 0.0292 0.2374
Leishmania major heat shock protein 83-1 0.0034 0.0292 0.2374
Schistosoma mansoni tsg101-related 0.006 0.0663 0.0657
Giardia lamblia Grp94/Hsp90 0.0027 0.0193 0.0959
Trypanosoma brucei heat shock protein, putative 0.0034 0.0292 0.2374
Schistosoma mansoni importin beta-1 0.003 0.0237 0.0231
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0061 0.0673 0.0667
Brugia malayi Heterochromatin protein 1 0.0073 0.0837 0.1304
Loa Loa (eye worm) hypothetical protein 0.0091 0.1097 0.1713
Loa Loa (eye worm) hypothetical protein 0.0028 0.0199 0.031
Echinococcus granulosus beta LACTamase domain containing family member 0.0038 0.034 0.034
Trichomonas vaginalis heat shock protein, putative 0.0027 0.0193 0.0566
Trypanosoma cruzi pyruvate kinase 2, putative 0.007 0.0797 0.6574
Echinococcus multilocularis pyruvate kinase 0.007 0.0797 0.0797
Loa Loa (eye worm) hypothetical protein 0.008 0.0946 0.1477
Onchocerca volvulus Pyruvate kinase homolog 0.007 0.0797 0.1236
Trypanosoma cruzi Heat shock protein 83, putative 0.0034 0.0292 0.2374
Brugia malayi PHD-finger family protein 0.0054 0.0571 0.0889
Schistosoma mansoni hypothetical protein 0.0016 0.0041 0.0035
Loa Loa (eye worm) hypothetical protein 0.002 0.0087 0.0136
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0054 0.0571 0.4696
Echinococcus granulosus dnaJ subfamily B 0.043 0.5901 0.5901
Echinococcus granulosus importin subunit beta 1 0.003 0.0237 0.0237
Leishmania major heat shock protein 83-1 0.0034 0.0292 0.2374
Schistosoma mansoni hypothetical protein 0.0016 0.0041 0.0035
Schistosoma mansoni intermediate filament proteins 0.0028 0.0206 0.02
Onchocerca volvulus 0.0466 0.6406 1
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0398 0.544 0.544
Plasmodium falciparum pyruvate kinase 0.007 0.0797 1
Echinococcus granulosus polycomb protein SCMH1 0.01 0.1223 0.1223
Schistosoma mansoni pyruvate kinase 0.0036 0.0316 0.031
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.01 0.1223 0.1217
Toxoplasma gondii PHD-finger domain-containing protein 0.002 0.009 0.1065
Trichomonas vaginalis chromobox protein, putative 0.0073 0.0837 0.251
Plasmodium falciparum pyruvate kinase 2 0.0036 0.0316 0.3912
Brugia malayi jmjC domain containing protein 0.008 0.0936 0.1458
Toxoplasma gondii LsmAD domain-containing protein 0.0027 0.0183 0.2238
Loa Loa (eye worm) latrophilin receptor protein 2 0.0016 0.0041 0.0064
Plasmodium vivax endoplasmin, putative 0.0034 0.0292 0.3612
Brugia malayi CHD4 protein 0.0018 0.0057 0.0087
Echinococcus granulosus jumonji domain containing protein 0.0085 0.1011 0.1011
Schistosoma mansoni hypothetical protein 0.002 0.009 0.0084
Brugia malayi pyruvate kinase 0.0015 0.0016 0.0023
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0018 0.0057 0.0057
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0069 0.0783 0.6452
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.002 0.009 0.07
Echinococcus multilocularis heat shock protein 90 0.0034 0.0292 0.0292
Trichomonas vaginalis chromobox protein, putative 0.0044 0.0428 0.1276
Brugia malayi Pre-SET motif family protein 0.0218 0.2891 0.4511
Brugia malayi Bromodomain containing protein 0.008 0.0944 0.1471
Schistosoma mansoni protein phosphatase 2C 0.002 0.0087 0.0081
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0029 0.0213 0.0207
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0054 0.0571 0.4696
Mycobacterium ulcerans UDP-galactopyranose mutase Glf 0.0594 0.8221 1
Toxoplasma gondii WD domain, G-beta repeat-containing protein 0.002 0.009 0.1065
Onchocerca volvulus Alhambra homolog 0.0061 0.0673 0.1041
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0019 0.0073 0.0202
Trichomonas vaginalis CMGC family protein kinase 0.0054 0.0571 0.1708
Toxoplasma gondii histone lysine methyltransferase SET1 0.0063 0.0705 0.8829
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0016 0.0028 0.0067
Mycobacterium ulcerans hypothetical protein 0.0038 0.034 0.0312
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0048 0.0483 0.0477
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0099 0.121 1
Trypanosoma cruzi PAB1-binding protein , putative 0.0027 0.0183 0.1471
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0114 0.1419 0.1419
Echinococcus multilocularis JmjC domain containing protein 4 0.002 0.0087 0.0087
Loa Loa (eye worm) heterochromatin protein 1 0.0073 0.0837 0.1306
Loa Loa (eye worm) hypothetical protein 0.0052 0.0544 0.0849
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.005 0.052 0.0809
Brugia malayi hypothetical protein 0.0466 0.6406 1
Schistosoma mansoni hypothetical protein 0.0355 0.4835 0.4832
Toxoplasma gondii heat shock protein 90, putative 0.0034 0.0292 0.3612
Schistosoma mansoni heat shock protein 0.0034 0.0292 0.0286
Loa Loa (eye worm) heat shock protein 90 0.0034 0.0292 0.0456
Echinococcus multilocularis chromobox protein 1 0.0073 0.0837 0.0837
Leishmania major hypothetical protein, conserved 0.0023 0.0136 0.1081
Echinococcus multilocularis peregrin 0.0066 0.0743 0.0743
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.0073 0.0202
Loa Loa (eye worm) hypothetical protein 0.0105 0.1291 0.2015
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0127 0.1603 0.1603
Trichomonas vaginalis ran, putative 0.0022 0.0124 0.0356
Echinococcus granulosus pyruvate kinase 0.007 0.0797 0.0797
Echinococcus multilocularis survival motor neuron protein 1 0.0247 0.33 0.33
Schistosoma mansoni hypothetical protein 0.0355 0.4835 0.4832
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0022 0.0124 0.0191
Trichomonas vaginalis CAMK family protein kinase 0.0099 0.121 0.3637
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0022 0.0124 0.0978
Loa Loa (eye worm) hypothetical protein 0.007 0.0797 0.1245
Plasmodium falciparum JmjC domain-containing protein, putative 0.002 0.0087 0.1021
Brugia malayi Pre-SET motif family protein 0.0032 0.0258 0.04
Loa Loa (eye worm) hypothetical protein 0.0067 0.0764 0.1193
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0038 0.0339 0.0339
Schistosoma mansoni endoplasmin 0.0034 0.0292 0.0286
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0018 0.0057 0.0051
Loa Loa (eye worm) hypothetical protein 0.0072 0.0835 0.1303
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.0073 0.0202
Echinococcus granulosus chromobox protein 1 0.0073 0.0837 0.0837
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0022 0.0124 0.0124
Schistosoma mansoni cpg binding protein 0.0036 0.0317 0.0311
Schistosoma mansoni chromobox protein 0.0073 0.0837 0.0831
Onchocerca volvulus 0.0044 0.0426 0.0657
Echinococcus multilocularis histone acetyltransferase MYST2 0.0114 0.1419 0.1419
Brugia malayi exodeoxyribonuclease III family protein 0.002 0.0086 0.0131
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0052 0.0544 0.0849
Schistosoma mansoni hypothetical protein 0.005 0.052 0.0514
Loa Loa (eye worm) hypothetical protein 0.0085 0.1016 0.1586
Plasmodium vivax hypothetical protein, conserved 0.0022 0.0117 0.1395
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.002 0.0086 0.0659
Entamoeba histolytica heat shock protein 90, putative 0.0034 0.0292 0.2374
Leishmania major heat shock protein 83-1 0.0034 0.0292 0.2374
Loa Loa (eye worm) pyruvate kinase 0.007 0.0797 0.1245
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0054 0.0571 0.4696
Echinococcus granulosus GPCR family 2 0.0016 0.0041 0.0041
Schistosoma mansoni zinc finger protein 0.0032 0.0262 0.0256
Onchocerca volvulus 0.0032 0.026 0.0397
Loa Loa (eye worm) hypothetical protein 0.0038 0.034 0.053
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.002 0.0086 0.0086
Trypanosoma cruzi polo-like protein kinase, putative 0.0099 0.121 1
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0127 0.1603 0.1603
Schistosoma mansoni myelin transcription factor 1 myt1 0.0114 0.1419 0.1413
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0075 0.0874 0.0874
Onchocerca volvulus Pyruvate kinase homolog 0.007 0.0797 0.1236
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0036 0.0314 0.0314
Echinococcus multilocularis dnaJ subfamily B 0.043 0.5901 0.5901
Echinococcus granulosus pyruvate kinase 0.007 0.0797 0.0797
Echinococcus multilocularis mitogen activated protein kinase 3 0.0054 0.0571 0.0571
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.002 0.0087 0.0671
Schistosoma mansoni phosphatidylserine receptor 0.002 0.0087 0.0081
Trypanosoma brucei heat shock protein, putative 0.0034 0.0292 0.2374
Echinococcus granulosus phd:f box containing protein 0.002 0.0087 0.0087
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0114 0.1419 0.2213
Trichomonas vaginalis CMGC family protein kinase 0.0054 0.0571 0.1708
Trichomonas vaginalis CAMK family protein kinase 0.0099 0.121 0.3637
Mycobacterium ulcerans esterase/lipase LipP 0.0038 0.034 0.0312
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0067 0.0764 0.0764
Trichomonas vaginalis CAMK family protein kinase 0.0099 0.121 0.3637
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0069 0.0783 0.0783
Mycobacterium tuberculosis UDP-galactopyranose mutase Glf (UDP-GALP mutase) (NAD+-flavin adenine dinucleotide-requiring enzyme) 0.0594 0.8221 1
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0054 0.0571 0.4696
Echinococcus granulosus fetal alzheimer antigen falz 0.0049 0.0501 0.0501
Loa Loa (eye worm) heat shock protein 75 0.0014 0.0006 0.001
Loa Loa (eye worm) hypothetical protein 0.0028 0.0206 0.0322
Schistosoma mansoni hypothetical protein 0.0016 0.0041 0.0035
Leishmania major hypothetical protein, conserved 0.0038 0.034 0.277
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0016 0.0041 0.0061
Schistosoma mansoni hypothetical protein 0.0038 0.0339 0.0333
Plasmodium falciparum ataxin-2 like protein, putative 0.0027 0.0183 0.2238
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.0073 0.0202
Loa Loa (eye worm) hypothetical protein 0.003 0.0237 0.037
Echinococcus multilocularis polycomb protein SCMH1 0.01 0.1223 0.1223
Toxoplasma gondii HEAT repeat-containing protein 0.003 0.0237 0.2921
Schistosoma mansoni hypothetical protein 0.0043 0.042 0.0414
Schistosoma mansoni lamin 0.0028 0.0206 0.02
Brugia malayi Pyruvate kinase, alpha/beta domain containing protein 0.0021 0.0107 0.0165
Echinococcus multilocularis pyruvate kinase 0.0036 0.0316 0.0316
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0075 0.0874 0.0874
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0028 0.0206 0.0322
Echinococcus multilocularis endoplasmin 0.0027 0.0193 0.0193
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0022 0.0124 0.1488
Plasmodium falciparum phd finger protein, putative 0.0061 0.0673 0.8424
Brugia malayi jmjC domain containing protein 0.002 0.0087 0.0133
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0022 0.0124 0.0978
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0048 0.0483 0.0477
Entamoeba histolytica pyruvate kinase, putative 0.0049 0.0498 0.4086
Trypanosoma brucei heat shock protein, putative 0.0034 0.0292 0.2374
Loa Loa (eye worm) hypothetical protein 0.01 0.1223 0.1909
Echinococcus multilocularis importin subunit beta 1 0.003 0.0237 0.0237
Echinococcus multilocularis pyruvate kinase 0.0036 0.0316 0.0316
Loa Loa (eye worm) jmjC domain-containing protein 0.0126 0.1594 0.2488
Trichomonas vaginalis conserved hypothetical protein 0.0016 0.0028 0.0067
Echinococcus granulosus heat shock protein 90 0.0027 0.0193 0.0193
Echinococcus granulosus survival motor neuron protein 1 0.0247 0.33 0.33
Trypanosoma cruzi heat shock protein 90, putative 0.0034 0.0292 0.2374
Loa Loa (eye worm) hypothetical protein 0.0148 0.1906 0.2975
Trichomonas vaginalis endoplasmin, putative 0.0021 0.0105 0.0298
Trypanosoma brucei hypothetical protein, conserved 0.0038 0.034 0.277
Entamoeba histolytica tumor susceptibility gene 101 protein, putative 0.0049 0.0506 0.4156
Giardia lamblia Kinase, CMGC MAPK 0.0054 0.0571 0.4322
Brugia malayi Intermediate filament tail domain containing protein 0.0028 0.0206 0.0319
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0044 0.0428 0.066
Echinococcus multilocularis heat shock protein 90 0.0027 0.0193 0.0193
Schistosoma mansoni methyl-cpg binding protein mbd 0.0036 0.0314 0.0308
Echinococcus multilocularis musashi 0.0028 0.0206 0.0206
Plasmodium vivax importin-beta 2, putative 0.003 0.0237 0.2921
Trichomonas vaginalis penicillin-binding protein, putative 0.0038 0.034 0.1007
Echinococcus granulosus transcription factor Dp 1 0.004 0.0372 0.0372
Trypanosoma cruzi heat shock protein 90, putative 0.0027 0.0193 0.1555
Loa Loa (eye worm) hypothetical protein 0.0016 0.0041 0.0064
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0048 0.0483 0.0483
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0016 0.0041 0.0041
Entamoeba histolytica hypothetical protein 0.0038 0.0339 0.2766
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.002 0.0086 0.0086
Schistosoma mansoni pyruvate kinase 0.007 0.0797 0.0792
Trichomonas vaginalis D-aminoacylase, putative 0.0038 0.034 0.1007
Schistosoma mansoni sex comb on midleg homolog 0.01 0.1223 0.1217
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0038 0.0339 0.0339
Brugia malayi F/Y-rich N-terminus family protein 0.0034 0.0294 0.0456
Loa Loa (eye worm) pyruvate kinase 0.007 0.0797 0.1245
Schistosoma mansoni hypothetical protein 0.0016 0.0041 0.0035
Trichomonas vaginalis CAMK family protein kinase 0.0099 0.121 0.3637
Brugia malayi Bromodomain containing protein 0.0066 0.0743 0.1157
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.02 0.2641 0.2641
Onchocerca volvulus 0.01 0.1223 0.1901
Plasmodium vivax SET domain protein, putative 0.0032 0.0258 0.3183
Trypanosoma cruzi hypothetical protein, conserved 0.0038 0.034 0.277
Brugia malayi jmjC domain containing protein 0.002 0.0087 0.0133
Leishmania major heat shock protein 83-1 0.0034 0.0292 0.2374
Echinococcus granulosus heat shock protein 0.0034 0.0292 0.0292
Giardia lamblia Pyruvate kinase 0.0036 0.0316 0.2047
Brugia malayi beta-lactamase family protein 0.0038 0.034 0.0527
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0048 0.0483 0.0483
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.002 0.0086 0.0134
Echinococcus granulosus heat shock protein 90 0.0034 0.0292 0.0292
Echinococcus multilocularis transcription factor Dp 1 0.004 0.0372 0.0372
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0025 0.0168 0.0168
Brugia malayi mbt repeat family protein 0.01 0.1223 0.1907
Toxoplasma gondii heat shock protein HSP90 0.0034 0.0292 0.3612
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.002 0.0087 0.1021
Leishmania major heat shock protein 83-1 0.0034 0.0292 0.2374
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0049 0.0501 0.0501
Brugia malayi hypothetical protein 0.0072 0.0835 0.1301
Echinococcus multilocularis heat shock protein 0.0034 0.0292 0.0292
Echinococcus multilocularis Kelch repeat type 1 0.0099 0.1207 0.1207
Onchocerca volvulus 0.0028 0.0206 0.0312
Echinococcus multilocularis zinc finger protein 0.0043 0.0413 0.0413
Trichomonas vaginalis heat shock protein, putative 0.0027 0.0193 0.0566
Trichomonas vaginalis CAMK family protein kinase 0.0099 0.121 0.3637
Echinococcus multilocularis geminin 0.0355 0.4835 0.4835
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0019 0.0073 0.0202
Echinococcus granulosus mitogen activated protein kinase 0.0054 0.0571 0.0571
Leishmania major heat shock protein 83-1 0.0034 0.0292 0.2374
Trichomonas vaginalis CAMK family protein kinase 0.0099 0.121 0.3637
Brugia malayi CXXC zinc finger family protein 0.003 0.0236 0.0365
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0052 0.0544 0.0847
Trypanosoma cruzi heat shock protein 85, putative 0.0034 0.0292 0.2374
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.0073 0.0202
Toxoplasma gondii pyruvate kinase PyKII 0.0036 0.0316 0.3912
Echinococcus multilocularis kelch ECH associated protein 1 0.0098 0.1203 0.1203
Loa Loa (eye worm) hypothetical protein 0.0466 0.6406 1
Trypanosoma cruzi heat shock protein 85, putative 0.0027 0.0193 0.1555
Plasmodium falciparum heat shock protein 90 0.0034 0.0292 0.3612
Echinococcus granulosus SAM and MBT domain containing protein 0.01 0.1223 0.1223
Mycobacterium tuberculosis Probable lipase LipD 0.0038 0.034 0.0312
Trypanosoma cruzi polo-like protein kinase, putative 0.0099 0.121 1
Toxoplasma gondii PHD-finger domain-containing protein 0.0061 0.0673 0.8424
Echinococcus granulosus heat shock protein heat shock protein 90 alpha 0.0027 0.0193 0.0193
Entamoeba histolytica hypothetical protein 0.0038 0.0339 0.2766
Brugia malayi RNA, U transporter 1 0.0086 0.1029 0.1604
Schistosoma mansoni pyruvate kinase 0.007 0.0797 0.0792
Leishmania major hypothetical protein, conserved 0.002 0.0087 0.0671
Schistosoma mansoni bromodomain containing protein 0.0134 0.1709 0.1704
Toxoplasma gondii ABC1 family protein 0.0038 0.034 0.4213
Brugia malayi Hsp90 protein 0.0014 0.0006 0.0007
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0385 0.1143
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0038 0.034 0.0312
Entamoeba histolytica hypothetical protein 0.0038 0.0339 0.2766
Echinococcus multilocularis lysine specific demethylase 6a 0.002 0.0087 0.0087
Leishmania major heat shock protein 83-1 0.0034 0.0292 0.2374
Chlamydia trachomatis pyruvate kinase 0.007 0.0797 0.5
Mycobacterium tuberculosis Probable lipase LipE 0.0038 0.034 0.0312
Onchocerca volvulus 0.005 0.052 0.0803
Leishmania major importin beta-1 subunit, putative 0.0025 0.0156 0.1246
Leishmania major heat shock protein 83-1 0.0034 0.0292 0.2374
Trichomonas vaginalis CAMK family protein kinase 0.0049 0.0505 0.1508
Leishmania major heat shock protein 83-1 0.0034 0.0292 0.2374
Brugia malayi hypothetical protein 0.0247 0.33 0.5151
Brugia malayi hypothetical protein 0.0038 0.0339 0.0527
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0099 0.121 0.1888
Brugia malayi serine/threonine-protein kinase plk-2 0.0099 0.121 0.1886
Mycobacterium tuberculosis Probable hydrolase 0.0038 0.034 0.0312
Echinococcus granulosus kelch ECH associated protein 1 like 0.0098 0.1203 0.1203
Schistosoma mansoni tsg101-related 0.006 0.0663 0.0657
Schistosoma mansoni jumonji/arid domain-containing protein 0.008 0.0936 0.093
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0038 0.034 0.0334
Loa Loa (eye worm) hypothetical protein 0.0032 0.026 0.0406
Plasmodium vivax hypothetical protein, conserved 0.0061 0.0673 0.8424
Echinococcus granulosus GTP binding nuclear protein Ran 0.0022 0.0124 0.0124
Echinococcus granulosus lysine specific demethylase 5A 0.008 0.0936 0.0936
Mycobacterium tuberculosis Conserved protein 0.0038 0.034 0.0312
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.002 0.0086 0.0659
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0067 0.0764 0.0758
Brugia malayi Importin beta-1 subunit 0.003 0.0237 0.0368
Brugia malayi mbt repeat family protein 0.01 0.1223 0.1907
Schistosoma mansoni tsg101-related 0.0049 0.0506 0.0501
Toxoplasma gondii exonuclease III APE 0.002 0.0086 0.1003
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0038 0.034 0.0312
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0032 0.0258 0.0258
Trypanosoma brucei heat shock protein, putative 0.0034 0.0292 0.2374
Plasmodium falciparum conserved Plasmodium membrane protein, unknown function 0.0022 0.0117 0.1395
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.002 0.0087 0.0671
Schistosoma mansoni lamin 0.0028 0.0206 0.02
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0069 0.0783 0.6452
Brugia malayi latrophilin 2 splice variant baaae 0.0036 0.0311 0.0483
Giardia lamblia Kinase, PLK 0.0099 0.121 1
Loa Loa (eye worm) bromodomain containing protein 0.0037 0.0332 0.0518
Schistosoma mansoni hypothetical protein 0.0324 0.4393 0.439
Entamoeba histolytica serine/threonine protein kinase, putative 0.0099 0.121 1
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0218 0.2891 0.4513

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

If you have references for this compound, please enter them in a user comment (below) or Contact us.