Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | hypothetical protein | 0.0037 | 0.0045 | 0.0126 |
Loa Loa (eye worm) | hypothetical protein | 0.0075 | 0.0909 | 0.2525 |
Loa Loa (eye worm) | hypothetical protein | 0.0075 | 0.0909 | 0.2525 |
Echinococcus granulosus | tumor protein p63 | 0.0389 | 0.7995 | 1 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0037 | 0.0045 | 0.0126 |
Mycobacterium ulcerans | lipase LipD | 0.0075 | 0.0909 | 0.5 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0109 | 0.1682 | 0.4674 |
Mycobacterium leprae | Probable lipase LipE | 0.0075 | 0.0909 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0075 | 0.0903 | 0.2511 |
Loa Loa (eye worm) | hypothetical protein | 0.0174 | 0.3145 | 0.8741 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0109 | 0.1682 | 0.4674 |
Schistosoma mansoni | cellular tumor antigen P53 | 0.0057 | 0.0506 | 0.1405 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0075 | 0.0909 | 0.2525 |
Brugia malayi | hypothetical protein | 0.0174 | 0.3145 | 0.8741 |
Entamoeba histolytica | hypothetical protein | 0.0037 | 0.0045 | 0.5 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0037 | 0.0045 | 0.0057 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0075 | 0.0909 | 0.5 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0075 | 0.0909 | 0.5 |
Schistosoma mansoni | tar DNA-binding protein | 0.0194 | 0.3598 | 1 |
Mycobacterium leprae | conserved hypothetical protein | 0.0075 | 0.0909 | 0.5 |
Onchocerca volvulus | 0.0075 | 0.0909 | 0.1526 | |
Brugia malayi | RNA binding protein | 0.0194 | 0.3598 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0194 | 0.3598 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0194 | 0.3598 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0194 | 0.3598 | 1 |
Loa Loa (eye worm) | TAR-binding protein | 0.0194 | 0.3598 | 1 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0075 | 0.0909 | 0.2525 |
Schistosoma mansoni | hypothetical protein | 0.0037 | 0.0045 | 0.0126 |
Mycobacterium ulcerans | esterase/lipase LipP | 0.0075 | 0.0909 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0109 | 0.1682 | 0.4674 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0075 | 0.0909 | 0.5 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0075 | 0.0909 | 0.2525 |
Onchocerca volvulus | 0.0075 | 0.0909 | 0.1526 | |
Trypanosoma brucei | hypothetical protein, conserved | 0.0075 | 0.0909 | 0.5 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0075 | 0.0909 | 0.1136 |
Loa Loa (eye worm) | RNA binding protein | 0.0194 | 0.3598 | 1 |
Onchocerca volvulus | 0.0075 | 0.0909 | 0.1526 | |
Loa Loa (eye worm) | hypothetical protein | 0.0057 | 0.0506 | 0.1405 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0194 | 0.3598 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0075 | 0.0909 | 0.2525 |
Loa Loa (eye worm) | hypothetical protein | 0.0075 | 0.0909 | 0.2525 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0075 | 0.0909 | 0.1136 |
Leishmania major | hypothetical protein, conserved | 0.0075 | 0.0909 | 0.5 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0109 | 0.1682 | 0.4674 |
Brugia malayi | beta-lactamase family protein | 0.0075 | 0.0909 | 0.2525 |
Mycobacterium ulcerans | fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE | 0.0075 | 0.0909 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0075 | 0.0909 | 0.2525 |
Mycobacterium ulcerans | beta-lactamase | 0.0075 | 0.0909 | 0.5 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0075 | 0.0909 | 0.5 |
Entamoeba histolytica | hypothetical protein | 0.0037 | 0.0045 | 0.5 |
Entamoeba histolytica | hypothetical protein | 0.0037 | 0.0045 | 0.5 |
Brugia malayi | beta-lactamase family protein | 0.0075 | 0.0909 | 0.2525 |
Echinococcus granulosus | tar DNA binding protein | 0.0194 | 0.3598 | 0.4501 |
Loa Loa (eye worm) | beta-lactamase | 0.0075 | 0.0909 | 0.2525 |
Echinococcus multilocularis | tar DNA binding protein | 0.0194 | 0.3598 | 0.4501 |
Mycobacterium ulcerans | hypothetical protein | 0.0075 | 0.0909 | 0.5 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0075 | 0.0909 | 0.5 |
Plasmodium vivax | hypothetical protein, conserved | 0.0075 | 0.0909 | 0.5 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0075 | 0.0909 | 0.5 |
Onchocerca volvulus | 0.0174 | 0.3145 | 1 | |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0037 | 0.0045 | 0.0057 |
Trichomonas vaginalis | esterase, putative | 0.0075 | 0.0909 | 0.5 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0194 | 0.3598 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0194 | 0.3598 | 1 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0075 | 0.0909 | 0.5 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0075 | 0.0909 | 0.2525 |
Toxoplasma gondii | ABC1 family protein | 0.0075 | 0.0909 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0075 | 0.0903 | 0.2511 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0075 | 0.0903 | 0.2511 |
Echinococcus multilocularis | tumor protein p63 | 0.0389 | 0.7995 | 1 |
Brugia malayi | TAR-binding protein | 0.0194 | 0.3598 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0037 | 0.0045 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0075 | 0.0909 | 0.2525 |
Brugia malayi | beta-lactamase | 0.0075 | 0.0909 | 0.2525 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.