Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.0074 | 0.0915 | 0.255 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0074 | 0.0915 | 0.255 |
Loa Loa (eye worm) | beta-lactamase | 0.0074 | 0.0915 | 0.255 |
Loa Loa (eye worm) | hypothetical protein | 0.0074 | 0.0915 | 0.255 |
Echinococcus granulosus | tar DNA binding protein | 0.0192 | 0.3589 | 0.445 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0074 | 0.0915 | 0.5 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0074 | 0.0915 | 0.5 |
Onchocerca volvulus | 0.0074 | 0.0915 | 0.1478 | |
Loa Loa (eye worm) | hypothetical protein | 0.0074 | 0.0915 | 0.255 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0074 | 0.0915 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0057 | 0.0522 | 0.1456 |
Loa Loa (eye worm) | RNA binding protein | 0.0192 | 0.3589 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0037 | 0.0074 | 0.5 |
Brugia malayi | beta-lactamase family protein | 0.0074 | 0.0915 | 0.255 |
Onchocerca volvulus | 0.0074 | 0.0915 | 0.1478 | |
Entamoeba histolytica | hypothetical protein | 0.0037 | 0.0074 | 0.5 |
Trichomonas vaginalis | esterase, putative | 0.0074 | 0.0915 | 0.5 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0074 | 0.0915 | 0.1135 |
Mycobacterium ulcerans | beta-lactamase | 0.0074 | 0.0915 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0107 | 0.1665 | 0.464 |
Loa Loa (eye worm) | hypothetical protein | 0.0074 | 0.0915 | 0.255 |
Brugia malayi | beta-lactamase family protein | 0.0074 | 0.0915 | 0.255 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0074 | 0.0915 | 0.5 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0074 | 0.0915 | 0.1135 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0074 | 0.0915 | 0.255 |
Toxoplasma gondii | ABC1 family protein | 0.0074 | 0.0915 | 0.5 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0192 | 0.3589 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0192 | 0.3589 | 1 |
Onchocerca volvulus | 0.0074 | 0.0915 | 0.1478 | |
Loa Loa (eye worm) | TAR-binding protein | 0.0192 | 0.3589 | 1 |
Mycobacterium ulcerans | lipase LipD | 0.0074 | 0.0915 | 0.5 |
Echinococcus multilocularis | tar DNA binding protein | 0.0192 | 0.3589 | 0.445 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0037 | 0.0074 | 0.0092 |
Brugia malayi | hypothetical protein | 0.0174 | 0.318 | 0.8862 |
Echinococcus multilocularis | tumor protein p63 | 0.0389 | 0.8064 | 1 |
Leishmania major | hypothetical protein, conserved | 0.0074 | 0.0915 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0073 | 0.0894 | 0.2492 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0074 | 0.0915 | 0.5 |
Mycobacterium ulcerans | esterase/lipase LipP | 0.0074 | 0.0915 | 0.5 |
Plasmodium vivax | hypothetical protein, conserved | 0.0074 | 0.0915 | 0.5 |
Brugia malayi | beta-lactamase | 0.0074 | 0.0915 | 0.255 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0074 | 0.0915 | 0.5 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0192 | 0.3589 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0037 | 0.0074 | 0.5 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0074 | 0.0915 | 0.5 |
Mycobacterium ulcerans | hypothetical protein | 0.0074 | 0.0915 | 0.5 |
Brugia malayi | hypothetical protein | 0.0037 | 0.0074 | 0.0207 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0107 | 0.1665 | 0.464 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0074 | 0.0915 | 0.255 |
Mycobacterium leprae | Probable lipase LipE | 0.0074 | 0.0915 | 0.5 |
Mycobacterium ulcerans | fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE | 0.0074 | 0.0915 | 0.5 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0037 | 0.0074 | 0.0207 |
Echinococcus granulosus | tumor protein p63 | 0.0389 | 0.8064 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0037 | 0.0074 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0073 | 0.0894 | 0.2492 |
Loa Loa (eye worm) | hypothetical protein | 0.0174 | 0.318 | 0.8862 |
Schistosoma mansoni | cellular tumor antigen P53 | 0.0057 | 0.0522 | 0.1456 |
Onchocerca volvulus | 0.0174 | 0.318 | 1 | |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0107 | 0.1665 | 0.464 |
Brugia malayi | RNA binding protein | 0.0192 | 0.3589 | 1 |
Mycobacterium leprae | conserved hypothetical protein | 0.0074 | 0.0915 | 0.5 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0074 | 0.0915 | 0.5 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0073 | 0.0894 | 0.2492 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0037 | 0.0074 | 0.0092 |
Loa Loa (eye worm) | hypothetical protein | 0.0074 | 0.0915 | 0.255 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0074 | 0.0915 | 0.255 |
Brugia malayi | TAR-binding protein | 0.0192 | 0.3589 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0192 | 0.3589 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0192 | 0.3589 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0192 | 0.3589 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0192 | 0.3589 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0074 | 0.0915 | 0.255 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0107 | 0.1665 | 0.464 |
Schistosoma mansoni | hypothetical protein | 0.0037 | 0.0074 | 0.0207 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.