TDR Targets

Basic information

Technical information

TDR Targets ID: 730100
Name: 1,4,5,6-tetrahydrocyclopenta[d]pyrazole-3-car bohydrazide
MW: 166.18 | Formula: C7H10N4O
H donors: 3 H acceptors: 2 LogP: -0.92 Rotable bonds: 2
Rule of 5 violations (Lipinski): 1
SMILES: NNC(=O)c1[nH]nc2c1CCC2
InChi: 1S/C7H10N4O/c8-9-7(12)6-4-2-1-3-5(4)10-11-6/h1-3,8H2,(H,9,12)(H,10,11)
InChiKey: SVCCSHLJCQVHGW-UHFFFAOYSA-N

Network

Hover on a compound node to display the structore

Target Layer

Model Organisms

Species	Viewmode
Arabidopsis thaliana
Caenorhabditis elegans
Dictyostelium discoideum
Drosophila melanogaster
Escherichia coli
Homo sapiens
Mus musculus
Oryza sativa
Saccharomyces cerevisiae
Schmidtea mediterranea
Other organisms

TDR Pathogens:

Species	Viewmode
Brugia malayi
Chlamydia trachomatis
Echinococcus granulosus
Entamoeba histolytica
Echinococcus multilocularis
Giardia lamblia
Leishmania major
Loa Loa (eye worm)
Mycobacterium leprae
Mycobacterium tuberculosis
Mycobacterium ulcerans
Onchocerca volvulus
Plasmodium falciparum
Plasmodium vivax
Schistosoma mansoni
Trypanosoma brucei
Trypanosoma cruzi
Toxoplasma gondii
Treponema pallidum
Trichomonas vaginalis
Wolbachia endosymbiont of Brugia malayi

Other Pathogens:

Species	Viewmode
Babesia bovis
Candida albicans
Cryptosporidium hominis
Cryptosporidium parvum
Leishmania braziliensis
Leishmania donovani
Leishmania infantum
Leishmania mexicana
Neospora caninum
Plasmodium berghei
Plasmodium knowlesi
Plasmodium yoelii
Schistosoma japonicum
Trypanosoma brucei gambiense
Trypanosoma congolense
Theileria parva

Compound Layer

This is a work in progress. Come back soon to try this features!

Clustering layers

This is a work in progress. Come back soon to try this features!

Synonyms

Oprea1_276019
ZINC00266940
Oprea1_641250

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology

No druggable targets predicted by orthology data

By sequence similarity to non orthologous known druggable targets

No druggable targets predicted by sequence similarity

Ranking Plot

Putative Targets List

Species	Potential target	Raw	Global	Species
Brugia malayi	hypothetical protein	0.0082	0.0241	0.1956
Toxoplasma gondii	LsmAD domain-containing protein	0.0127	0.045	0.369
Echinococcus granulosus	thyroid hormone receptor alpha	0.0078	0.0224	0.0224
Loa Loa (eye worm)	hypothetical protein	0.0291	0.121	1
Onchocerca volvulus		0.0166	0.0632	0.5202
Echinococcus multilocularis	nuclear receptor 2DBD gamma	0.0166	0.0632	0.0654
Loa Loa (eye worm)	nuclear hormone receptor family member nhr-31	0.0166	0.0632	0.5202
Toxoplasma gondii	ABC1 family protein	0.0291	0.121	1
Loa Loa (eye worm)	hypothetical protein	0.0291	0.121	1
Loa Loa (eye worm)	hypothetical protein	0.0166	0.0632	0.5202
Brugia malayi	nuclear hormone receptor	0.0078	0.0224	0.1818
Loa Loa (eye worm)	hypothetical protein	0.0078	0.0224	0.1818
Loa Loa (eye worm)	nuclear Hormone Receptor family member	0.0166	0.0632	0.5202
Loa Loa (eye worm)	hypothetical protein	0.0166	0.0632	0.5202
Mycobacterium tuberculosis	Probable conserved lipoprotein	0.0291	0.121	0.1359
Mycobacterium leprae	Probable lipase LipE	0.0291	0.121	1
Schistosoma mansoni	apoferritin-2	0.0044	0.0066	0.0061
Brugia malayi	beta-lactamase family protein	0.0291	0.121	1
Loa Loa (eye worm)	DR-78	0.0078	0.0224	0.1818
Onchocerca volvulus		0.0078	0.0224	0.1818
Brugia malayi	Nuclear hormone receptor family member nhr-40	0.0166	0.0632	0.5202
Onchocerca volvulus		0.0291	0.121	1
Trypanosoma cruzi	cysteine peptidase, putative	0.0067	0.017	0.0599
Mycobacterium tuberculosis	Probable lipase LipE	0.0291	0.121	0.1359
Echinococcus multilocularis	Ataxin 2, N terminal,domain containing protein	0.0057	0.0125	0.0125
Echinococcus multilocularis	expressed protein	0.0044	0.0066	0.0063
Brugia malayi	Nuclear hormone receptor-like 1	0.0088	0.0268	0.218
Loa Loa (eye worm)	transcription factor SMAD2	0.0122	0.0424	0.3479
Brugia malayi	nuclear receptor RXR	0.0078	0.0224	0.1818
Brugia malayi	Nuclear hormone receptor family member nhr-1	0.0166	0.0632	0.5202
Trichomonas vaginalis	D-aminoacylase, putative	0.0291	0.121	1
Loa Loa (eye worm)	hypothetical protein	0.0078	0.0224	0.1818
Schistosoma mansoni	ferritin light chain	0.0044	0.0066	0.0061
Schistosoma mansoni	retinoid-x-receptor (RXR)	0.0088	0.0268	0.0263
Echinococcus multilocularis	Nuclear hormone receptor HR96	0.0078	0.0224	0.0229
Schistosoma mansoni	nuclear hormone receptor nor-1/nor-2	0.0166	0.0632	0.0627
Brugia malayi	hypothetical protein	0.0088	0.0268	0.218
Brugia malayi	beta-lactamase	0.0291	0.121	1
Echinococcus granulosus	nuclear receptor 2DBD gamma	0.0166	0.0632	0.0632
Brugia malayi	Nuclear hormone receptor family member nhr-31	0.0166	0.0632	0.5202
Loa Loa (eye worm)	hypothetical protein	0.0078	0.0224	0.1818
Schistosoma mansoni	family S12 unassigned peptidase (S12 family)	0.0291	0.121	0.1206
Loa Loa (eye worm)	hypothetical protein	0.0078	0.0224	0.1818
Schistosoma mansoni	ferritin	0.0044	0.0066	0.0061
Echinococcus multilocularis	beta LACTamase domain containing family member	0.0291	0.121	0.1257
Mycobacterium ulcerans	esterase/lipase LipP	0.0291	0.121	1
Trichomonas vaginalis	set domain proteins, putative	0.0248	0.1011	0.8256
Schistosoma mansoni	nuclear hormone receptor	0.0078	0.0224	0.0219
Loa Loa (eye worm)	hypothetical protein	0.0088	0.0268	0.218
Onchocerca volvulus	Bile acid receptor homolog	0.0166	0.0632	0.5202
Onchocerca volvulus		0.0291	0.121	1
Echinococcus granulosus	Nuclear hormone receptor HR96	0.0078	0.0224	0.0224
Schistosoma mansoni	hepatocyte nuclear factor 4-alpha (hnf-4-alpha)	0.0078	0.0224	0.0219
Schistosoma mansoni	FTZ-F1 nuclear receptor-like protein	0.0166	0.0632	0.0627
Echinococcus multilocularis	retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha	0.2097	0.9592	1
Loa Loa (eye worm)	pigment dispersing factor receptor c	0.0052	0.0102	0.0806
Brugia malayi	Corticotropin releasing factor receptor 2 precursor, putative	0.0052	0.0102	0.0806
Trypanosoma cruzi	hypothetical protein, conserved	0.0291	0.121	1
Brugia malayi	Ligand-binding domain of nuclear hormone receptor family protein	0.0166	0.0632	0.5202
Loa Loa (eye worm)	hypothetical protein	0.0166	0.0632	0.5202
Brugia malayi	Nuclear hormone receptor-like 1	0.0166	0.0632	0.5202
Schistosoma mansoni	ecdysone-induced protein 78c (dr-78)	0.0088	0.0268	0.0263
Trypanosoma brucei	hypothetical protein, conserved	0.0291	0.121	1
Onchocerca volvulus	Nuclear receptor subfamily 6 group A member 1 homolog	0.0078	0.0224	0.1818
Brugia malayi	Pre-SET motif family protein	0.0218	0.0871	0.7185
Mycobacterium tuberculosis	Probable esterase/lipase LipP	0.0291	0.121	0.1359
Echinococcus granulosus	nuclear receptor subfamily 4 group A	0.0078	0.0224	0.0224
Schistosoma mansoni	coup transcription factor	0.0166	0.0632	0.0627
Brugia malayi	photoreceptor-specific nuclear receptor	0.0166	0.0632	0.5202
Loa Loa (eye worm)	hypothetical protein	0.0088	0.0268	0.218
Echinococcus granulosus	Ataxin 2 N terminaldomain containing protein	0.0057	0.0125	0.0125
Brugia malayi	nuclear hormone receptor	0.0166	0.0632	0.5202
Echinococcus granulosus	FTZ F1 alpha	0.0166	0.0632	0.0632
Brugia malayi	nuclear receptor RXR	0.0088	0.0268	0.218
Brugia malayi	MH2 domain containing protein	0.0122	0.0424	0.3479
Onchocerca volvulus	Protein ultraspiracle homolog	0.0166	0.0632	0.5202
Trypanosoma cruzi	cysteine peptidase, putative	0.0067	0.017	0.0599
Brugia malayi	Steroid receptor seven-up type 2	0.0166	0.0632	0.5202
Onchocerca volvulus	Nuclear receptor subfamily 6 group A member 1 homolog	0.0078	0.0224	0.1818
Brugia malayi	hypothetical protein	0.0078	0.0224	0.1818
Loa Loa (eye worm)	nuclear hormone receptor family member nhr-41	0.0166	0.0632	0.5202
Loa Loa (eye worm)	hypothetical protein	0.0166	0.0632	0.5202
Brugia malayi	steroid hormone receptor	0.0166	0.0632	0.5202
Schistosoma mansoni	nuclear receptor nhr-48	0.0078	0.0224	0.0219
Trichomonas vaginalis	penicillin-binding protein, putative	0.0291	0.121	1
Loa Loa (eye worm)	hypothetical protein	0.0078	0.0224	0.1818
Loa Loa (eye worm)	hypothetical protein	0.0291	0.121	1
Brugia malayi	Nuclear hormone receptor-like 1	0.0088	0.0268	0.218
Echinococcus multilocularis	nuclear receptor subfamily 1 group D	0.0088	0.0268	0.0274
Loa Loa (eye worm)	hypothetical protein	0.0166	0.0632	0.5202
Mycobacterium tuberculosis	Probable lipase LipD	0.0291	0.121	0.1359
Brugia malayi	Nuclear hormone receptor family member nhr-25	0.0166	0.0632	0.5202
Schistosoma mansoni	nuclear receptor	0.0078	0.0224	0.0219
Brugia malayi	hypothetical protein	0.0088	0.0268	0.218
Brugia malayi	nuclear hormone receptor family member nhr-6	0.0078	0.0224	0.1818
Schistosoma mansoni	thyroid hormone receptor	0.0166	0.0632	0.0627
Schistosoma mansoni	ferritin	0.0044	0.0066	0.0061
Plasmodium vivax	hypothetical protein, conserved	0.0291	0.121	1
Echinococcus multilocularis	Nuclear hormone receptor family member nhr 41	0.0166	0.0632	0.0654
Schistosoma mansoni	cellular tumor antigen P53	0.005	0.0091	0.0085
Loa Loa (eye worm)	nuclear hormone receptor family member nhr-40	0.0166	0.0632	0.5202
Trichomonas vaginalis	esterase, putative	0.0291	0.121	1
Loa Loa (eye worm)	nuclear hormone receptor family member nhr-49	0.0166	0.0632	0.5202
Schistosoma mansoni	photoreceptor-specific nuclear receptor related	0.0166	0.0632	0.0627
Echinococcus multilocularis	COUP TF:Svp nuclear hormone receptor	0.0166	0.0632	0.0654
Schistosoma mansoni	retinoid-x-receptor (RXR)	0.0166	0.0632	0.0627
Schistosoma mansoni	ferritin light chain	0.0044	0.0066	0.0061
Echinococcus multilocularis	tumor protein p63	0.0339	0.1433	0.149
Trichomonas vaginalis	D-aminoacylase, putative	0.0291	0.121	1
Trypanosoma cruzi	cysteine peptidase, putative	0.0067	0.017	0.0599
Loa Loa (eye worm)	hypothetical protein	0.0291	0.121	1
Schistosoma mansoni	nuclear hormone receptor	0.0078	0.0224	0.0219
Brugia malayi	nuclear receptor NHR-88	0.0078	0.0224	0.1818
Loa Loa (eye worm)	beta-lactamase	0.0291	0.121	1
Brugia malayi	nuclear receptor NHR-67	0.0078	0.0224	0.1818
Schistosoma mansoni	nuclear receptor	0.0078	0.0224	0.0219
Trypanosoma cruzi	hypothetical protein, conserved	0.0291	0.121	1
Loa Loa (eye worm)	hypothetical protein	0.0078	0.0224	0.1818
Plasmodium falciparum	ataxin-2 like protein, putative	0.0127	0.045	0.5
Brugia malayi	orphan nuclear receptor NR2E1	0.0078	0.0224	0.1818
Mycobacterium tuberculosis	Possible penicillin-binding protein	0.1859	0.8484	1
Loa Loa (eye worm)	steroid hormone receptor	0.0166	0.0632	0.5202
Loa Loa (eye worm)	nuclear receptor nhr-7B	0.0078	0.0224	0.1818
Loa Loa (eye worm)	hypothetical protein	0.0036	0.0026	0.017
Brugia malayi	nuclear hormone receptor family member odr-7	0.0078	0.0224	0.1818
Onchocerca volvulus		0.0078	0.0224	0.1818
Schistosoma mansoni	Tr4/Tr2 (homologue)	0.0166	0.0632	0.0627
Loa Loa (eye worm)	pre-SET domain-containing protein family protein	0.0218	0.0871	0.7185
Onchocerca volvulus	Steroid hormone receptor family member cnr14 homolog	0.0166	0.0632	0.5202
Brugia malayi	Nuclear hormone receptor family member nhr-14	0.0166	0.0632	0.5202
Schistosoma mansoni	hypothetical protein	0.0057	0.0125	0.012
Loa Loa (eye worm)	hypothetical protein	0.0166	0.0632	0.5202
Echinococcus granulosus	ferritin	0.0044	0.0066	0.0066
Loa Loa (eye worm)	hypothetical protein	0.0078	0.0224	0.1818
Brugia malayi	Calcitonin receptor-like protein seb-1	0.0052	0.0102	0.0806
Echinococcus granulosus	FTZ F1 nuclear receptor protein	0.0166	0.0632	0.0632
Echinococcus multilocularis	nuclear receptor 2DBD gamma	0.0078	0.0224	0.0229
Trichomonas vaginalis	D-aminoacylase, putative	0.0291	0.121	1
Loa Loa (eye worm)	hypothetical protein	0.0291	0.121	1
Brugia malayi	Nuclear hormone receptor family member nhr-19	0.0166	0.0632	0.5202
Leishmania major	hypothetical protein, conserved	0.0291	0.121	1
Loa Loa (eye worm)	hypothetical protein	0.0078	0.0224	0.1818
Mycobacterium tuberculosis	Conserved protein	0.0291	0.121	0.1359
Mycobacterium ulcerans	fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE	0.0291	0.121	1
Echinococcus granulosus	tumor protein p63	0.0339	0.1433	0.1433
Echinococcus granulosus	nuclear receptor subfamily 1 group D	0.0088	0.0268	0.0268
Plasmodium vivax	ataxin-2 like protein, putative	0.0127	0.045	0.369
Echinococcus multilocularis	ecdysone induced protein 78C	0.0166	0.0632	0.0654
Trypanosoma brucei	PAB1-binding protein , putative	0.0127	0.045	0.269
Mycobacterium ulcerans	lipase LipD	0.0291	0.121	1
Schistosoma mansoni	thyroid hormone receptor	0.0166	0.0632	0.0627
Echinococcus granulosus	hepatocyte nuclear factor 4 alpha	0.0166	0.0632	0.0632
Schistosoma mansoni	nuclear receptor 2DBD-gamma	0.0166	0.0632	0.0627
Loa Loa (eye worm)	hypothetical protein	0.0166	0.0632	0.5202
Brugia malayi	hypothetical protein	0.0127	0.045	0.369
Schistosoma mansoni	nuclear hormone receptor superfamily protein-related	0.0078	0.0224	0.0219
Brugia malayi	Nuclear hormone receptor family member nhr-19	0.0166	0.0632	0.5202
Brugia malayi	Nuclear hormone receptor family member nhr-3	0.0166	0.0632	0.5202
Echinococcus multilocularis	FTZ F1 alpha	0.0166	0.0632	0.0654
Brugia malayi	beta-lactamase family protein	0.0291	0.121	1
Loa Loa (eye worm)	hypothetical protein	0.0078	0.0224	0.1818
Loa Loa (eye worm)	hypothetical protein	0.0078	0.0224	0.1818
Loa Loa (eye worm)	nuclear hormone receptor-like 1	0.0088	0.0268	0.218
Echinococcus multilocularis	nuclear receptor subfamily 4 group A	0.0078	0.0224	0.0229
Mycobacterium tuberculosis	Probable hydrolase	0.0291	0.121	0.1359
Loa Loa (eye worm)	beta-LACTamase domain containing family member	0.0291	0.121	1
Loa Loa (eye worm)	nuclear hormone receptor	0.0078	0.0224	0.1818
Loa Loa (eye worm)	nuclear hormone receptor family member nhr-1	0.0166	0.0632	0.5202
Echinococcus multilocularis	nuclear receptor nhr 48	0.0078	0.0224	0.0229
Brugia malayi	ecdysteroid receptor	0.0166	0.0632	0.5202
Schistosoma mansoni	ferritin	0.0044	0.0066	0.0061
Loa Loa (eye worm)	nuclear receptor NHR-67	0.0078	0.0224	0.1818
Mycobacterium leprae	conserved hypothetical protein	0.0291	0.121	1
Schistosoma mansoni	family S12 unassigned peptidase (S12 family)	0.0291	0.121	0.1206
Loa Loa (eye worm)	hypothetical protein	0.005	0.0091	0.0708
Brugia malayi	hypothetical protein	0.0078	0.0224	0.1818
Echinococcus granulosus	Nuclear hormone receptor HR96	0.0078	0.0224	0.0224
Onchocerca volvulus		0.0248	0.1011	0.8344
Loa Loa (eye worm)	hypothetical protein	0.0291	0.121	1
Trypanosoma cruzi	cysteine peptidase, clan CA, family C1, cathepsin L-like, putative	0.0061	0.0143	0.0356
Loa Loa (eye worm)	hypothetical protein	0.0088	0.0268	0.218
Loa Loa (eye worm)	hypothetical protein	0.0078	0.0224	0.1818
Onchocerca volvulus		0.005	0.0091	0.0708
Echinococcus granulosus	Nuclear hormone receptor family member nhr 41	0.0166	0.0632	0.0632
Echinococcus granulosus	COUP TF:Svp nuclear hormone receptor	0.0166	0.0632	0.0632
Echinococcus granulosus	beta LACTamase domain containing family member	0.0291	0.121	0.121
Loa Loa (eye worm)	hypothetical protein	0.0078	0.0224	0.1818
Loa Loa (eye worm)	hypothetical protein	0.0088	0.0268	0.218
Trichomonas vaginalis	penicillin-binding protein, putative	0.0291	0.121	1
Echinococcus multilocularis	thyroid hormone receptor alpha	0.0166	0.0632	0.0654
Loa Loa (eye worm)	MH2 domain-containing protein	0.0122	0.0424	0.3479
Plasmodium falciparum	ataxin-2 like protein, putative	0.0127	0.045	0.5
Schistosoma mansoni	nuclear hormone receptor	0.0166	0.0632	0.0627
Wolbachia endosymbiont of Brugia malayi	bacterioferritin/cytochrome b1	0.0044	0.0066	0.5
Brugia malayi	nuclear receptor subfamily 1, group D, member 1, putative	0.0078	0.0224	0.1818
Mycobacterium tuberculosis	Probable esterase LipL	0.0291	0.121	0.1359
Brugia malayi	Nuclear hormone receptor family member nhr-41	0.0166	0.0632	0.5202
Echinococcus granulosus	histone lysine methyltransferase setb	0.0031	0.0005	0.0005
Onchocerca volvulus		0.0291	0.121	1
Mycobacterium ulcerans	beta-lactamase	0.0291	0.121	1
Echinococcus granulosus	expressed protein	0.0044	0.0066	0.0066
Echinococcus multilocularis	FTZ F1 nuclear receptor protein	0.0166	0.0632	0.0654
Schistosoma mansoni	retinoic acid receptor RXR	0.2185	1	1
Loa Loa (eye worm)	hypothetical protein	0.0078	0.0224	0.1818
Schistosoma mansoni	steroid hormone receptor ad4bp	0.0166	0.0632	0.0627
Brugia malayi	latrophilin 2 splice variant baaae	0.0036	0.0026	0.017
Mycobacterium ulcerans	hypothetical protein	0.0291	0.121	1
Echinococcus granulosus	nuclear receptor nhr 48	0.0078	0.0224	0.0224
Brugia malayi	conserved hypotetical protein	0.0078	0.0224	0.1818
Mycobacterium tuberculosis	Conserved protein	0.0291	0.121	0.1359
Echinococcus multilocularis	Nuclear hormone receptor HR96	0.0078	0.0224	0.0229
Loa Loa (eye worm)	hypothetical protein	0.0127	0.045	0.369
Mycobacterium tuberculosis	Conserved protein	0.0291	0.121	0.1359
Brugia malayi	Nuclear hormone receptor family member nhr-25	0.0166	0.0632	0.5202
Echinococcus multilocularis	ferritin	0.0044	0.0066	0.0063
Echinococcus multilocularis	hepatocyte nuclear factor 4 alpha	0.0166	0.0632	0.0654
Trypanosoma cruzi	cruzipain precursor, putative	0.0067	0.017	0.0599
Treponema pallidum	bacterioferrin (TpF1)	0.0044	0.0066	0.5
Loa Loa (eye worm)	hypothetical protein	0.0088	0.0268	0.218
Brugia malayi	tailless protein	0.0078	0.0224	0.1818
Brugia malayi	Nuclear hormone receptor family member nhr-49	0.0166	0.0632	0.5202
Echinococcus granulosus	nuclear receptor 2DBD gamma	0.0078	0.0224	0.0224
Schistosoma mansoni	ferritin	0.0044	0.0066	0.0061
Brugia malayi	Ligand-binding domain of nuclear hormone receptor family protein	0.0166	0.0632	0.5202
Echinococcus granulosus	ecdysone induced protein 78C	0.0166	0.0632	0.0632
Loa Loa (eye worm)	hypothetical protein	0.0166	0.0632	0.5202
Schistosoma mansoni	RAR-like nuclear receptor	0.0166	0.0632	0.0627
Schistosoma mansoni	zinc finger protein	0.0078	0.0224	0.0219
Trypanosoma cruzi	PAB1-binding protein , putative	0.0127	0.045	0.3128
Schistosoma mansoni	hypothetical protein	0.0036	0.0026	0.0021
Trypanosoma cruzi	PAB1-binding protein , putative	0.0127	0.045	0.3128
Leishmania major	hypothetical protein, conserved	0.0127	0.045	0.269
Brugia malayi	Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative	0.0291	0.121	1
Brugia malayi	Nuclear hormone receptor E75	0.0078	0.0224	0.1818
Schistosoma mansoni	apoferritin-2	0.0044	0.0066	0.0061
Brugia malayi	ecdysone receptor	0.0078	0.0224	0.1818
Brugia malayi	nuclear receptor NHR-88	0.0166	0.0632	0.5202
Echinococcus granulosus	nuclear receptor 2DBD gamma	0.0166	0.0632	0.0632
Loa Loa (eye worm)	nuclear hormone receptor family member nhr-14	0.0166	0.0632	0.5202
Loa Loa (eye worm)	hypothetical protein	0.0052	0.0102	0.0806
Brugia malayi	Nuclear hormone receptor E75	0.0078	0.0224	0.1818
Mycobacterium tuberculosis	Possible conserved lipoprotein LpqK	0.0291	0.121	0.1359
Echinococcus multilocularis	nuclear receptor 2DBD gamma	0.0166	0.0632	0.0654

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Search by Saint Jude

Bibliographic References

No literature references available for this target.

If you have references for this compound, please enter them in a user comment (below) or Contact us.

Detailed information for compound 730100