Detailed information for compound 730624

Basic information

Technical information
  • TDR Targets ID: 730624
  • Name: N-(3-bromophenyl)-2-[[5-(4-chlorophenyl)-1H-1 ,2,4-triazol-3-yl]sulfanyl]acetamide
  • MW: 423.715 | Formula: C16H12BrClN4OS
  • H donors: 2 H acceptors: 3 LogP: 4.02 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 1
  • SMILES: O=C(Nc1cccc(c1)Br)CSc1[nH]nc(n1)c1ccc(cc1)Cl
  • InChi: 1S/C16H12BrClN4OS/c17-11-2-1-3-13(8-11)19-14(23)9-24-16-20-15(21-22-16)10-4-6-12(18)7-5-10/h1-8H,9H2,(H,19,23)(H,20,21,22)
  • InChiKey: DUWWBNBCAXAVML-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • N-(3-bromophenyl)-2-[[5-(4-chlorophenyl)-1H-1,2,4-triazol-3-yl]thio]acetamide
  • N-(3-bromophenyl)-2-[[5-(4-chlorophenyl)-1H-1,2,4-triazol-3-yl]sulfanyl]ethanamide
  • CBKinase1_022438
  • CBKinase1_010038

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) hypothetical protein 0.0612 0.2143 0.548
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0126 0.0393 0.0393
Loa Loa (eye worm) hypothetical protein 0.0148 0.0473 0.1205
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0126 0.0393 0.0999
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0059 0.0154 0.0151
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0024 0.0028 0.0025
Echinococcus granulosus thyroid hormone receptor alpha 0.0059 0.0154 0.0151
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0033 0.0058 0.0055
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0126 0.0393 0.0999
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0066 0.0179 0.0707
Echinococcus granulosus GTP binding nuclear protein Ran 0.0021 0.0016 0.0013
Schistosoma mansoni hypothetical protein 0.1236 0.439 0.439
Echinococcus granulosus Nuclear hormone receptor HR96 0.0059 0.0154 0.0151
Loa Loa (eye worm) hypothetical protein 0.0059 0.0154 0.0387
Trichomonas vaginalis glutathione reductase, putative 0.0249 0.0838 0.4246
Wolbachia endosymbiont of Brugia malayi ATP-dependent Clp protease proteolytic subunit 0.008 0.0228 0.1782
Schistosoma mansoni ran 0.0021 0.0016 0.0016
Schistosoma mansoni smad 0.0034 0.0061 0.0061
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0249 0.0838 0.3312
Trypanosoma brucei 2,4-dienoyl-coa reductase-like protein 0.0066 0.0179 0.0707
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0033 0.0058 0.0058
Trypanosoma cruzi PAB1-binding protein , putative 0.0053 0.0131 0.0516
Onchocerca volvulus 0.01 0.0302 0.0942
Trypanosoma cruzi PAB1-binding protein , putative 0.0053 0.0131 0.0516
Trichomonas vaginalis dihydropyrimidine dehydrogenase, putative 0.0066 0.0179 0.0895
Brugia malayi acetyltransferase, GNAT family protein 0.0148 0.0474 0.1207
Entamoeba histolytica disulphide oxidoreductase, putative 0.0066 0.0179 0.0823
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0061 0.0162 0.0159
Echinococcus multilocularis ATP dependent Clp protease proteolytic subunit 0.008 0.0228 0.0226
Brugia malayi Bromodomain containing protein 0.0045 0.0102 0.0255
Mycobacterium ulcerans lipase LipD 0.0148 0.0473 0.2397
Mycobacterium ulcerans glutamate synthase subunit beta 0.0066 0.0179 0.0902
Brugia malayi Patched family protein 0.0037 0.0074 0.0183
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0039 0.008 0.0077
Loa Loa (eye worm) hypothetical protein 0.0059 0.0154 0.0387
Trypanosoma cruzi heat shock protein 85, putative 0.0046 0.0106 0.042
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0148 0.0474 0.0472
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0144 0.0457 0.0455
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0059 0.0154 0.0154
Schistosoma mansoni patched 1 0.0263 0.0886 0.0886
Loa Loa (eye worm) hypothetical protein 0.0126 0.0393 0.0999
Echinococcus granulosus Smad4 0.0075 0.0211 0.0208
Brugia malayi nuclear hormone receptor 0.0126 0.0393 0.0999
Echinococcus granulosus heat shock protein 0.0046 0.0106 0.0104
Echinococcus granulosus tumor protein p63 0.0686 0.2411 0.2409
Trypanosoma cruzi polo-like protein kinase, putative 0.0398 0.1373 0.5426
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0126 0.0393 0.0999
Echinococcus granulosus heat shock protein 90 0.0039 0.0082 0.008
Echinococcus granulosus snurportin 1 0.0304 0.1034 0.1032
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0049 0.0116 0.0113
Loa Loa (eye worm) hypothetical protein 0.0037 0.0074 0.0183
Schistosoma mansoni disulfide oxidoreductase 0.0066 0.0179 0.0179
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0126 0.0393 0.0999
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0066 0.0179 0.0176
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0031 0.0051 0.02
Echinococcus multilocularis FTZ F1 alpha 0.0126 0.0393 0.039
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0024 0.0106
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0082 0.0236 0.0236
Schistosoma mansoni hypothetical protein 0.0125 0.0391 0.0391
Schistosoma mansoni zinc finger protein 0.0059 0.0154 0.0154
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0126 0.0393 0.1282
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0066 0.0179 0.0697
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0126 0.0393 0.0393
Echinococcus granulosus ATP dependent Clp protease proteolytic subunit 0.008 0.0228 0.0226
Trichomonas vaginalis PIKK family atypical protein kinase 0.0055 0.0137 0.0682
Trichomonas vaginalis CAMK family protein kinase 0.0398 0.1373 0.6965
Trichomonas vaginalis ran, putative 0.0021 0.0016 0.0067
Trichomonas vaginalis CAMK family protein kinase 0.0197 0.065 0.3289
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0033 0.0058 0.0055
Brugia malayi Patched family protein 0.0037 0.0074 0.0183
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0059 0.0154 0.0154
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.1824 0.6509 1
Trypanosoma brucei heat shock protein, putative 0.0046 0.0106 0.042
Trichomonas vaginalis CAMK family protein kinase 0.0398 0.1373 0.6965
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0148 0.0473 0.0473
Echinococcus granulosus expressed conserved protein 0.0575 0.201 0.2007
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) 0.0052 0.0129 0.0197
Mycobacterium tuberculosis Probable dehydrogenase 0.1641 0.5849 0.8987
Toxoplasma gondii ABC1 family protein 0.0148 0.0473 0.1861
Entamoeba histolytica hypothetical protein 0.0187 0.0616 0.2863
Brugia malayi AMP-binding enzyme family protein 0.005 0.0121 0.0302
Trichomonas vaginalis CAMK family protein kinase 0.0398 0.1373 0.6965
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSB 0.0043 0.0096 0.0145
Trichomonas vaginalis PIKK family atypical protein kinase 0.0068 0.0185 0.0926
Loa Loa (eye worm) hypothetical protein 0.0037 0.0074 0.0183
Mycobacterium tuberculosis Putative ferredoxin reductase 0.1641 0.5849 0.8987
Giardia lamblia Heat shock protein HSP 90-alpha 0.0046 0.0106 0.0666
Entamoeba histolytica hypothetical protein 0.0187 0.0616 0.2863
Trypanosoma cruzi hypothetical protein, conserved 0.0066 0.0179 0.0707
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0187 0.0616 0.0613
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0075 0.0211 0.0208
Schistosoma mansoni hypothetical protein 0.0253 0.0852 0.0852
Loa Loa (eye worm) hypothetical protein 0.0037 0.0074 0.0183
Toxoplasma gondii type I fatty acid synthase, putative 0.0038 0.0078 0.0297
Loa Loa (eye worm) fatty acid synthase 0.0053 0.0131 0.0328
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0249 0.0838 0.3305
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0445 0.1542 0.3939
Brugia malayi nuclear hormone receptor family member odr-7 0.0059 0.0154 0.0387
Mycobacterium tuberculosis Probable esterase LipL 0.0148 0.0473 0.0726
Echinococcus granulosus mothers against decapentaplegic 5 0.0075 0.0211 0.0208
Brugia malayi Nuclear hormone receptor-like 1 0.0066 0.018 0.0453
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0154 0.0494 0.1258
Brugia malayi nuclear receptor RXR 0.0066 0.018 0.0453
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0148 0.0473 0.0726
Leishmania major hypothetical protein, conserved 0.0148 0.0473 0.187
Schistosoma mansoni coup transcription factor 0.0126 0.0393 0.0393
Leishmania major GTP-binding protein, putative 0.0021 0.0016 0.0063
Loa Loa (eye worm) MH2 domain-containing protein 0.0034 0.0061 0.015
Schistosoma mansoni zinc finger protein 0.0025 0.0029 0.0029
Leishmania major trypanothione reductase 0.072 0.2531 1
Leishmania major 2,4-dienoyl-coa reductase-like protein 0.0066 0.0179 0.0707
Mycobacterium tuberculosis Polyketide synthase Pks12 0.0057 0.0145 0.0222
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0066 0.0179 0.0895
Trypanosoma cruzi hypothetical protein, conserved 0.0148 0.0473 0.187
Trypanosoma cruzi NADH dehydrogenase, putative 0.0066 0.0179 0.0707
Wolbachia endosymbiont of Brugia malayi thioredoxin reductase 0.0066 0.0179 0.1114
Onchocerca volvulus 0.0772 0.272 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0078 0.0221 0.111
Trichomonas vaginalis CAMK family protein kinase 0.0398 0.1373 0.6965
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0059 0.0154 0.0387
Giardia lamblia NADH oxidase lateral transfer candidate 0.0249 0.0838 0.6058
Trichomonas vaginalis PIKK family atypical protein kinase 0.0068 0.0185 0.0926
Loa Loa (eye worm) heat shock protein 75 0.0031 0.0051 0.0123
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0031 0.0051 0.02
Plasmodium falciparum histone acetyltransferase GCN5 0.0039 0.0082 0.0262
Loa Loa (eye worm) hypothetical protein 0.01 0.0302 0.0767
Echinococcus multilocularis mothers against decapentaplegic 6 0.0034 0.0061 0.0059
Brugia malayi Patched family protein 0.0037 0.0074 0.0183
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0126 0.0393 0.039
Loa Loa (eye worm) hypothetical protein 0.0059 0.0154 0.0387
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0249 0.0838 0.3312
Loa Loa (eye worm) hypothetical protein 0.0059 0.0154 0.0387
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0249 0.0838 0.3312
Echinococcus multilocularis apoptosis inducing factor 1 mitochondrial 0.0066 0.0179 0.0176
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0033 0.0058 0.0087
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0126 0.0393 0.039
Leishmania major heat shock protein 83-1 0.0046 0.0106 0.042
Echinococcus granulosus importin subunit beta 1 0.0028 0.0043 0.004
Schistosoma mansoni tar DNA-binding protein 0.0136 0.0431 0.0431
Loa Loa (eye worm) pyridine nucleotide-disufhide oxidoreductase 0.0066 0.0179 0.0451
Brugia malayi RNA recognition motif domain containing protein 0.0136 0.0431 0.1097
Loa Loa (eye worm) hypothetical protein 0.0148 0.0473 0.1205
Schistosoma mansoni microtubule-associated protein tau 0.2794 1 1
Plasmodium vivax basic transcription factor 3b, putative 0.0075 0.0211 0.0777
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0249 0.0838 1
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0126 0.0393 0.039
Trichomonas vaginalis ferritin, putative 0.0052 0.0127 0.0634
Loa Loa (eye worm) hypothetical protein 0.0126 0.0393 0.0999
Echinococcus multilocularis ferritin 0.0052 0.0127 0.0125
Echinococcus multilocularis microtubule associated protein 2 0.2794 1 1
Loa Loa (eye worm) MH2 domain-containing protein 0.0075 0.0211 0.0533
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) 0.0052 0.0129 0.0197
Treponema pallidum thioredoxin reductase (trxB) 0.0066 0.0179 0.1742
Brugia malayi nuclear receptor NHR-88 0.0059 0.0154 0.0387
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0398 0.1373 0.3509
Brugia malayi MH2 domain containing protein 0.0034 0.0061 0.015
Loa Loa (eye worm) hypothetical protein 0.0082 0.0236 0.0598
Mycobacterium ulcerans NADH dehydrogenase 0.0066 0.0179 0.0902
Trichomonas vaginalis heat shock protein, putative 0.0043 0.0096 0.0475
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0126 0.0393 0.0999
Echinococcus multilocularis muscleblind protein 0.0147 0.0471 0.0469
Brugia malayi MH2 domain containing protein 0.0075 0.0211 0.0533
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0091 0.0269 0.0269
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) 0.0052 0.0129 0.0197
Schistosoma mansoni heat shock protein 0.0031 0.0051 0.0051
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0066 0.0179 0.0176
Trichomonas vaginalis dihydrolipoamide dehydrogenase, putative 0.0066 0.0179 0.0895
Leishmania major heat shock protein 83-1 0.0046 0.0106 0.042
Echinococcus granulosus transcription factor btf3 0.0075 0.0211 0.0209
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0126 0.0393 0.0999
Entamoeba histolytica serine/threonine protein kinase, putative 0.0398 0.1373 0.6404
Trichomonas vaginalis endoplasmin, putative 0.0033 0.0061 0.0296
Trichomonas vaginalis esterase, putative 0.0148 0.0473 0.2391
Trichomonas vaginalis heat shock protein, putative 0.0046 0.0106 0.0527
Trypanosoma cruzi trypanothione reductase, putative 0.0249 0.0838 0.3312
Leishmania major hypothetical protein, conserved 0.0053 0.0131 0.0516
Echinococcus granulosus NADPH:adrenodoxin oxidoreductase 0.0066 0.0179 0.0176
Echinococcus multilocularis isocitrate dehydrogenase 0.0033 0.0058 0.0055
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0066 0.0179 0.0895
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.1641 0.5849 0.8987
Schistosoma mansoni smad1 5 8 and 0.0075 0.0211 0.0211
Leishmania major heat shock protein 83-1 0.0046 0.0106 0.042
Loa Loa (eye worm) hypothetical protein 0.0037 0.0074 0.0183
Leishmania major heat shock protein 83-1 0.0046 0.0106 0.042
Trypanosoma brucei heat shock protein 90, putative 0.0046 0.0106 0.042
Treponema pallidum heat shock protein 90 0.0043 0.0096 0.0707
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprA 0.0066 0.0179 0.0902
Schistosoma mansoni RAR-like nuclear receptor 0.0126 0.0393 0.0393
Plasmodium vivax hypothetical protein, conserved 0.0148 0.0473 0.1818
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsC 0.0057 0.0145 0.0732
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0126 0.0393 0.039
Loa Loa (eye worm) hypothetical protein 0.0148 0.0473 0.1205
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0059 0.0154 0.0387
Schistosoma mansoni steroid hormone receptor ad4bp 0.0126 0.0393 0.0393
Echinococcus multilocularis Smad4 0.0075 0.0211 0.0208
Echinococcus multilocularis protein dispatched 1 0.03 0.1019 0.1017
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0049 0.0116 0.0113
Loa Loa (eye worm) hypothetical protein 0.0037 0.0074 0.0183
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0064 0.017 0.0663
Loa Loa (eye worm) hypothetical protein 0.0037 0.0074 0.0183
Toxoplasma gondii patched family protein 0.0037 0.0074 0.0283
Mycobacterium tuberculosis Conserved protein 0.0148 0.0473 0.0726
Brugia malayi hypothetical protein 0.0059 0.0154 0.0387
Mycobacterium ulcerans beta-lactamase 0.0148 0.0473 0.2397
Echinococcus multilocularis thyroid hormone receptor alpha 0.0251 0.0844 0.0841
Mycobacterium ulcerans hypothetical protein 0.0066 0.0179 0.0902
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0148 0.0473 0.0726
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0249 0.0838 0.2139
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0126 0.0393 0.0393
Schistosoma mansoni sulfide quinone reductase 0.0066 0.0179 0.0179
Trichomonas vaginalis CAMK family protein kinase 0.0398 0.1373 0.6965
Schistosoma mansoni bromodomain containing protein 0.0072 0.0199 0.0199
Loa Loa (eye worm) TAR-binding protein 0.0136 0.0431 0.1097
Loa Loa (eye worm) DR-78 0.0059 0.0154 0.0387
Toxoplasma gondii NAC domain-containing protein 0.0075 0.0211 0.0825
Loa Loa (eye worm) hypothetical protein 0.0059 0.0154 0.0387
Trypanosoma cruzi heat shock protein 90, putative 0.0039 0.0082 0.0326
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0091 0.0269 0.1063
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0126 0.0393 0.0999
Trichomonas vaginalis PIKK family atypical protein kinase 0.0049 0.0118 0.0586
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0144 0.0457 0.1164
Echinococcus granulosus histone acetyltransferase KAT2B 0.0045 0.0104 0.0101
Brugia malayi Patched family protein 0.0037 0.0074 0.0183
Trypanosoma cruzi heat shock protein 90, putative 0.0019 0.001 0.0039
Brugia malayi photoreceptor-specific nuclear receptor 0.0126 0.0393 0.0999
Loa Loa (eye worm) hypothetical protein 0.0066 0.018 0.0453
Schistosoma mansoni ferritin 0.0052 0.0127 0.0127
Trichomonas vaginalis PIKK family atypical protein kinase 0.0068 0.0185 0.0926
Entamoeba histolytica heat shock transcription factor, putative 0.0205 0.068 0.3165
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0031 0.0051 0.0051
Onchocerca volvulus 0.0037 0.0074 0.0088
Loa Loa (eye worm) hypothetical protein 0.005 0.0119 0.0298
Trichomonas vaginalis PIKK family atypical protein kinase 0.0073 0.0202 0.1012
Brugia malayi Patched family protein 0.0037 0.0074 0.0183
Echinococcus multilocularis geminin 0.1236 0.439 0.4388
Loa Loa (eye worm) acetyltransferase 0.0148 0.0474 0.1207
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0021 0.0016 0.0063
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0187 0.0616 0.0613
Mycobacterium ulcerans thioesterase 0.0045 0.0101 0.0508
Toxoplasma gondii non-proton pumping type-II NADH dehydrogenase I 0.0066 0.0179 0.0697
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSC 0.0057 0.0145 0.0222
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0021 0.0016 0.0034
Loa Loa (eye worm) hypothetical protein 0.0037 0.0074 0.0183
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0249 0.0838 0.3269
Trichomonas vaginalis conserved hypothetical protein 0.0075 0.0211 0.106
Loa Loa (eye worm) hypothetical protein 0.0059 0.0154 0.0387
Echinococcus multilocularis heat shock protein 75 kDa, mitochondrial 0.0031 0.0051 0.0048
Brugia malayi Calcitonin receptor-like protein seb-1 0.0154 0.0494 0.1258
Onchocerca volvulus 0.005 0.0121 0.0262
Brugia malayi MH1 domain containing protein 0.0075 0.0211 0.0533
Loa Loa (eye worm) glutathione reductase 0.072 0.2531 0.6472
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsE 0.0035 0.0068 0.034
Loa Loa (eye worm) hypothetical protein 0.0126 0.0393 0.0999
Brugia malayi oxidoreductase, zinc-binding dehydrogenase family protein 0.0101 0.0306 0.0776
Echinococcus granulosus sulfide:quinone oxidoreductase 0.0066 0.0179 0.0176
Giardia lamblia Kinase, PLK 0.0398 0.1373 1
Schistosoma mansoni ran 0.0021 0.0016 0.0016
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0148 0.0473 0.1205
Mycobacterium ulcerans ferredoxin reductase 0.0066 0.0179 0.0902
Echinococcus multilocularis endoplasmin 0.0043 0.0096 0.0093
Toxoplasma gondii type I fatty acid synthase, putative 0.0057 0.0145 0.0564
Trichomonas vaginalis apoptosis inducing factor, putative 0.0066 0.0179 0.0895
Echinococcus granulosus mothers against decapentaplegic 2 0.0034 0.0061 0.0059
Trichomonas vaginalis PIKK family atypical protein kinase 0.0049 0.0118 0.0586
Trypanosoma cruzi 2,4-dienoyl-coa reductase-like protein, putative 0.0066 0.0179 0.0707
Trypanosoma cruzi heat shock protein 85, putative 0.0046 0.0106 0.042
Schistosoma mansoni methyl-cpg binding protein mbd 0.0018 0.0007 0.0007
Loa Loa (eye worm) hypothetical protein 0.0147 0.0471 0.1199
Plasmodium vivax glutathione reductase, putative 0.072 0.2531 1
Mycobacterium leprae PROBABLE NADPH:ADRENODOXIN OXIDOREDUCTASE FPRB (ADRENODOXIN REDUCTASE) (AR) (FERREDOXIN-NADP(+) REDUCTASE) 0.0066 0.0179 0.0273
Loa Loa (eye worm) hypothetical protein 0.0019 0.001 0.0018
Toxoplasma gondii isocitrate dehydrogenase 0.0033 0.0058 0.0218
Loa Loa (eye worm) hypothetical protein 0.0114 0.035 0.0888
Leishmania major heat shock protein 83-1 0.0046 0.0106 0.042
Loa Loa (eye worm) hypothetical protein 0.0066 0.018 0.0453
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0249 0.0838 0.3312
Brugia malayi protein C24B5.3 0.0037 0.0074 0.0183
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0031 0.0051 0.0048
Echinococcus multilocularis transcription factor eb 0.0114 0.0352 0.0349
Loa Loa (eye worm) transcription factor SMAD2 0.1102 0.3909 1
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0066 0.0179 0.0707
Giardia lamblia Thioredoxin reductase 0.0066 0.0179 0.12
Mycobacterium ulcerans polyketide synthase Pks13 0.008 0.0229 0.1155
Brugia malayi NADPH:adrenodoxin oxidoreductase, mitochondrial precursor 0.0066 0.0179 0.0451
Trypanosoma cruzi hypothetical protein, conserved 0.0066 0.0179 0.0707
Schistosoma mansoni sulfide quinone reductase 0.0066 0.0179 0.0179
Mycobacterium ulcerans dehydrogenase 0.0066 0.0179 0.0902
Plasmodium vivax heat shock protein, putative 0.0175 0.0569 0.2199
Onchocerca volvulus 0.0059 0.0154 0.0387
Entamoeba histolytica heat shock protein 90, putative 0.0046 0.0106 0.0484
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSD 0.0054 0.0133 0.0203
Schistosoma mansoni nuclear receptor nhr-48 0.0059 0.0154 0.0154
Brugia malayi protein C24B5.3 0.0037 0.0074 0.0183
Entamoeba histolytica heat shock transcription factor, putative 0.0205 0.068 0.3165
Echinococcus multilocularis glutamate synthase 0.0066 0.0179 0.0176
Brugia malayi Patched family protein 0.0037 0.0074 0.0183
Toxoplasma gondii patched family protein 0.0037 0.0074 0.0283
Schistosoma mansoni ferritin 0.0052 0.0127 0.0127
Echinococcus multilocularis expressed conserved protein 0.0575 0.201 0.2007
Brugia malayi Latrophilin receptor protein 2 0.0049 0.0116 0.0289
Trichomonas vaginalis PIKK family atypical protein kinase 0.0091 0.0269 0.1354
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0091 0.0269 0.0266
Trichomonas vaginalis PIKK family atypical protein kinase 0.0054 0.0135 0.0672
Echinococcus granulosus glutamate synthase 0.0066 0.0179 0.0176
Plasmodium vivax ataxin-2 like protein, putative 0.0053 0.0131 0.0456
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.1641 0.5849 0.8987
Onchocerca volvulus 0.0506 0.1763 0.6413
Entamoeba histolytica transcription factor BTF3, putative 0.0075 0.0211 0.0974
Echinococcus granulosus GPCR family 2 0.0049 0.0116 0.0113
Schistosoma mansoni tar DNA-binding protein 0.0136 0.0431 0.0431
Schistosoma mansoni nuclear receptor 0.0059 0.0154 0.0154
Schistosoma mansoni glutamate synthase 0.0066 0.0179 0.0179
Trichomonas vaginalis PIKK family atypical protein kinase 0.0061 0.0161 0.0804
Trichomonas vaginalis heat shock protein, putative 0.0027 0.0037 0.0174
Trichomonas vaginalis PIKK family atypical protein kinase 0.0059 0.0154 0.0768
Mycobacterium ulcerans bacterioferritin BfrB 0.0052 0.0127 0.0642
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0126 0.0393 0.0393
Toxoplasma gondii LsmAD domain-containing protein 0.0053 0.0131 0.0506
Trypanosoma brucei NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0066 0.0179 0.0707
Mycobacterium ulcerans polyketide synthase Pks9 0.0035 0.0068 0.034
Loa Loa (eye worm) hypothetical protein 0.0076 0.0215 0.0544
Plasmodium falciparum glutathione reductase 0.072 0.2531 1
Leishmania major 2,4-dienoyl-coa reductase fadh1, putative 0.0066 0.0179 0.0707
Echinococcus multilocularis peptidase Clp (S14 family) 0.0052 0.0129 0.0127
Mycobacterium tuberculosis Probable lipase LipE 0.0148 0.0473 0.0726
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0183 0.06 0.1529
Trypanosoma cruzi NADH dehydrogenase, putative 0.0066 0.0179 0.0707
Echinococcus multilocularis ATP binding cassette sub family B 0.0131 0.0412 0.0409
Trichomonas vaginalis heat shock protein, putative 0.0043 0.0096 0.0475
Loa Loa (eye worm) hypothetical protein 0.0037 0.0074 0.0183
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0059 0.0154 0.0151
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.005 0.0121 0.0184
Echinococcus multilocularis tar DNA binding protein 0.0136 0.0431 0.0428
Leishmania major heat shock protein 83-1 0.0046 0.0106 0.042
Brugia malayi glutamate synthase 0.0066 0.0179 0.0451
Echinococcus granulosus transcription factor eb 0.0114 0.0352 0.0349
Schistosoma mansoni thyroid hormone receptor 0.0251 0.0844 0.0844
Trypanosoma cruzi trypanothione reductase, putative 0.072 0.2531 1
Mycobacterium tuberculosis Polyketide synthase Pks13 0.008 0.0229 0.035
Brugia malayi Muscleblind-like protein 0.0147 0.0471 0.1199
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0033 0.0058 0.0229
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0049 0.0116 0.0113
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0018 0.0007 0.0004
Mycobacterium ulcerans lipoprotein LpqF 0.0064 0.0171 0.0863
Echinococcus multilocularis ecdysone induced protein 78C 0.0126 0.0393 0.039
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0024 0.0026 0.0023
Leishmania major basic transcription factor 3a, putative 0.0075 0.0211 0.0835
Trichomonas vaginalis penicillin-binding protein, putative 0.0148 0.0473 0.2391
Mycobacterium tuberculosis Probable conserved lipoprotein LpqF 0.0064 0.0171 0.0261
Loa Loa (eye worm) hypothetical protein 0.0147 0.0471 0.1199
Loa Loa (eye worm) hypothetical protein 0.0037 0.0074 0.0183
Leishmania major heat shock protein 83-1 0.0046 0.0106 0.042
Loa Loa (eye worm) MH1 domain-containing protein 0.0075 0.0211 0.0533
Brugia malayi Smad1 0.0075 0.0211 0.0533
Mycobacterium tuberculosis Probable polyketide synthase Pks5 0.0052 0.0127 0.0194
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0126 0.0393 0.0999
Trichomonas vaginalis PIKK family atypical protein kinase 0.0049 0.0118 0.0586
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0024 0.0028 0.0028
Onchocerca volvulus Protein patched homolog 0.0037 0.0074 0.0088
Mycobacterium tuberculosis NADPH:adrenodoxin oxidoreductase FprA (NADPH-ferredoxin reductase) 0.0066 0.0179 0.0273
Brugia malayi orphan nuclear receptor NR2E1 0.0059 0.0154 0.0387
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.0016 0.0063
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0073 0.0202 0.0799
Onchocerca volvulus 0.0093 0.0276 0.0844
Echinococcus granulosus heat shock protein 75 kDa mitochondrial 0.0031 0.0051 0.0048
Echinococcus multilocularis thioredoxin glutathione reductase 0.0723 0.2542 0.254
Plasmodium falciparum heat shock protein 90 0.0046 0.0106 0.0359
Loa Loa (eye worm) hypothetical protein 0.0037 0.0074 0.0183
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0249 0.0838 0.3269
Echinococcus multilocularis NADPH:adrenodoxin oxidoreductase 0.0066 0.0179 0.0176
Mycobacterium tuberculosis Probable multifunctional mycocerosic acid synthase membrane-associated Mas 0.0057 0.0145 0.0222
Brugia malayi Steroid receptor seven-up type 2 0.0126 0.0393 0.0999
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0126 0.0393 0.0999
Trypanosoma brucei trypanothione reductase 0.072 0.2531 1
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0249 0.0838 1
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0249 0.0838 0.3312
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0144 0.0457 0.0455
Schistosoma mansoni serine/threonine protein kinase 0.0398 0.1373 0.1373
Mycobacterium tuberculosis Conserved protein 0.0148 0.0473 0.0726
Brugia malayi RNA, U transporter 1 0.0081 0.0232 0.0587
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0249 0.0838 0.3269
Mycobacterium tuberculosis Probable NADPH:adrenodoxin oxidoreductase FprB (adrenodoxin reductase) (AR) (ferredoxin-NADP(+) reductase) 0.0066 0.0179 0.0273
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0068 0.0185 0.0183
Loa Loa (eye worm) patched family protein 0.0037 0.0074 0.0183
Mycobacterium tuberculosis Probable NADPH dependent 2,4-dienoyl-CoA reductase FadH (2,4-dienoyl coenzyme A reductase) (4-enoyl-CoA reductase) 0.0066 0.0179 0.0273
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0066 0.0179 0.0697
Loa Loa (eye worm) hypothetical protein 0.0126 0.0393 0.0999
Schistosoma mansoni Smad4 0.0034 0.0061 0.0061
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0398 0.1373 0.5426
Brugia malayi Patched family protein 0.0037 0.0074 0.0183
Mycobacterium tuberculosis Probable bacterioferritin BfrA 0.0052 0.0127 0.0194
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0066 0.0179 0.0176
Loa Loa (eye worm) hypothetical protein 0.0126 0.0393 0.0999
Schistosoma mansoni hypothetical protein 0.0049 0.0116 0.0116
Trichomonas vaginalis PIKK family atypical protein kinase 0.0068 0.0185 0.0926
Giardia lamblia Grp94/Hsp90 0.0043 0.0096 0.0591
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0126 0.0393 0.0393
Trypanosoma brucei heat shock protein, putative 0.0046 0.0106 0.042
Trypanosoma brucei transcription factor BTF3, putative 0.0075 0.0211 0.0835
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsA 0.0054 0.0133 0.0203
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0033 0.0058 0.0055
Echinococcus granulosus nuclear receptor nhr 48 0.0059 0.0154 0.0151
Loa Loa (eye worm) MH2 domain-containing protein 0.1102 0.3909 1
Schistosoma mansoni hypothetical protein 0.0049 0.0116 0.0116
Schistosoma mansoni ferritin light chain 0.0052 0.0127 0.0127
Loa Loa (eye worm) hypothetical protein 0.0066 0.018 0.0453
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0249 0.0838 0.0838
Brugia malayi MH2 domain containing protein 0.1102 0.3909 1
Trypanosoma brucei phosphatidylinositol kinase related protein, putative 0.0017 0.0003 0.0011
Plasmodium vivax endoplasmin, putative 0.0046 0.0106 0.0359
Echinococcus granulosus heat shock protein heat shock protein 90 alpha 0.0039 0.0082 0.008
Brugia malayi hypothetical protein 0.0066 0.018 0.0453
Plasmodium falciparum NAD(P)H-dependent glutamate synthase, putative 0.0066 0.0179 0.0648
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.0016 0.0063
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0031 0.0051 0.0048
Leishmania major heat shock protein 83-1 0.0046 0.0106 0.042
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0027 0.0038 0.014
Brugia malayi hypothetical protein 0.0037 0.0074 0.0183
Mycobacterium ulcerans Type I modular polyketide synthase 0.0054 0.0133 0.0671
Loa Loa (eye worm) hypothetical protein 0.0066 0.018 0.0453
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0249 0.0838 0.425
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0148 0.0473 0.2397
Brugia malayi steroid hormone receptor 0.0126 0.0393 0.0999
Brugia malayi hypothetical protein 0.0187 0.0616 0.1569
Echinococcus multilocularis ATP binding cassette sub family B 0.0131 0.0412 0.0409
Echinococcus multilocularis Niemann Pick C1 protein 0.0874 0.3088 0.3086
Toxoplasma gondii selenide, water dikinase 0.0066 0.0179 0.0697
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.008 0.0228 0.2363
Brugia malayi Patched family protein 0.0037 0.0074 0.0183
Toxoplasma gondii thioredoxin reductase 0.072 0.2531 1
Mycobacterium leprae Probable polyketide synthase Pks1 0.0057 0.0145 0.0222
Onchocerca volvulus Protein ultraspiracle homolog 0.0126 0.0393 0.1282
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.1641 0.5849 0.8987
Mycobacterium leprae Probable multifunctional mycocerosic acid synthase membrane associated enzyme Mas 0.0057 0.0145 0.0222
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0068 0.0185 0.0183
Echinococcus granulosus FTZ F1 alpha 0.0126 0.0393 0.039
Onchocerca volvulus 0.0059 0.0154 0.0387
Echinococcus granulosus mothers against decapentaplegic 6 0.0034 0.0061 0.0059
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0126 0.0393 0.0999
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.0017 0.0003 0.0011
Schistosoma mansoni tar DNA-binding protein 0.0136 0.0431 0.0431
Echinococcus multilocularis muscleblind protein 1 0.0147 0.0471 0.0469
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0021 0.0016 0.0013
Schistosoma mansoni hypothetical protein 0.0253 0.0852 0.0852
Trichomonas vaginalis PIKK family atypical protein kinase 0.0031 0.0051 0.0244
Trichomonas vaginalis PIKK family atypical protein kinase 0.0031 0.0051 0.0244
Brugia malayi Bromodomain containing protein 0.0085 0.0245 0.062
Trypanosoma brucei heat shock protein, putative 0.0046 0.0106 0.042
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0249 0.0838 0.0836
Leishmania major heat shock protein 83-1 0.0046 0.0106 0.042
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0066 0.018 0.018
Brugia malayi Endoplasmin precursor 0.0046 0.0106 0.0265
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0263 0.0886 0.2261
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0091 0.0269 0.1063
Trichomonas vaginalis CAMK family protein kinase 0.0197 0.065 0.3289
Brugia malayi Helix-loop-helix DNA-binding domain containing protein 0.0114 0.0352 0.0893
Brugia malayi Nuclear hormone receptor E75 0.0059 0.0154 0.0387
Loa Loa (eye worm) phosphatidylinositol 3 0.0091 0.0269 0.0682
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0136 0.0431 0.1097
Loa Loa (eye worm) hypothetical protein 0.0059 0.0154 0.0387
Loa Loa (eye worm) heat shock protein 90 0.0046 0.0106 0.0265
Onchocerca volvulus 0.0126 0.0393 0.1282
Mycobacterium ulcerans NADH dehydrogenase Ndh 0.0066 0.0179 0.0902
Brugia malayi heat shock protein 90 0.0046 0.0106 0.0265
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.008 0.0228 0.0845
Toxoplasma gondii isocitrate dehydrogenase 0.0033 0.0058 0.0218
Loa Loa (eye worm) glutaminase 0.0564 0.197 0.5038
Loa Loa (eye worm) ICD-1 protein 0.0075 0.0211 0.0534
Entamoeba histolytica thioredoxin reductase, putative 0.0066 0.0179 0.0823
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0045 0.0104 0.0401
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0066 0.0179 0.0707
Loa Loa (eye worm) hypothetical protein 0.0037 0.0074 0.0183
Brugia malayi Patched related family protein 10 0.0037 0.0074 0.0183
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsD 0.0054 0.0133 0.0671
Loa Loa (eye worm) Smad1 0.0075 0.0211 0.0533
Giardia lamblia GTOR 0.0091 0.0269 0.1865
Loa Loa (eye worm) programmed cell death 8 0.0066 0.0179 0.0451
Schistosoma mansoni glutaminase 0.0564 0.197 0.197
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0249 0.0838 0.3269
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0028 0.004 0.0095
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0017 0.0003 0.0011
Brugia malayi nuclear receptor RXR 0.0059 0.0154 0.0387
Mycobacterium ulcerans heat shock protein 90 0.0043 0.0096 0.0483
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.072 0.2531 0.3887
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0148 0.0473 0.0473
Loa Loa (eye worm) nuclear receptor NHR-67 0.0059 0.0154 0.0387
Loa Loa (eye worm) hypothetical protein 0.0037 0.0074 0.0183
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0148 0.0474 0.0474
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0154 0.0494 0.1258
Trypanosoma brucei hypothetical protein, conserved 0.0066 0.0179 0.0707
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0126 0.0393 0.0999
Toxoplasma gondii patched family protein 0.0037 0.0074 0.0283
Toxoplasma gondii NADPH-glutathione reductase 0.0249 0.0838 0.3305
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0033 0.0058 0.0055
Trichomonas vaginalis set domain proteins, putative 0.0506 0.1763 0.8944
Brugia malayi hypothetical protein 0.0037 0.0074 0.0183
Entamoeba histolytica hypothetical protein 0.0187 0.0616 0.2863
Trichomonas vaginalis penicillin-binding protein, putative 0.0148 0.0473 0.2391
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0066 0.018 0.018
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0126 0.0393 0.039
Trichomonas vaginalis PIKK family atypical protein kinase 0.0049 0.0118 0.0584
Mycobacterium leprae PROBABLE BACTERIOFERRITIN BFRA 0.0052 0.0127 0.0194
Echinococcus multilocularis expressed protein 0.0052 0.0127 0.0125
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0066 0.018 0.0177
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0126 0.0393 0.0393
Loa Loa (eye worm) hypothetical protein 0.0066 0.018 0.0453
Leishmania major phosphatidylinositol 3-kinase, putative 0.0031 0.0051 0.02
Mycobacterium tuberculosis Probable polyketide synthase Pks1 0.0038 0.0079 0.012
Loa Loa (eye worm) hypothetical protein 0.0105 0.0319 0.081
Schistosoma mansoni hypothetical protein 0.0253 0.0852 0.0852
Echinococcus granulosus peptidase Clp S14 family 0.0052 0.0129 0.0127
Entamoeba histolytica hypothetical protein 0.0023 0.0024 0.0098
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0126 0.0393 0.0999
Plasmodium falciparum thioredoxin reductase 0.0249 0.0838 0.3269
Schistosoma mansoni nuclear hormone receptor 0.0059 0.0154 0.0154
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0059 0.0154 0.0387
Brugia malayi Patched family protein 0.0037 0.0074 0.0183
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0126 0.0393 0.039
Trichomonas vaginalis PIKK family atypical protein kinase 0.0091 0.0269 0.1354
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0144 0.0457 0.0457
Schistosoma mansoni peptidase Clp (S14 family) 0.008 0.0228 0.0228
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsA 0.0043 0.0096 0.048
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0066 0.0179 0.0895
Onchocerca volvulus 0.0066 0.0179 0.048
Brugia malayi Pre-SET motif family protein 0.0064 0.017 0.0429
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0126 0.0393 0.039
Entamoeba histolytica hypothetical protein 0.0187 0.0616 0.2863
Brugia malayi conserved hypotetical protein 0.0059 0.0154 0.0387
Echinococcus multilocularis zinc finger protein 0.0025 0.0029 0.0027
Schistosoma mansoni apoferritin-2 0.0052 0.0127 0.0127
Treponema pallidum bacterioferrin (TpF1) 0.0052 0.0127 0.1099
Brugia malayi MH1 domain containing protein 0.0042 0.009 0.0224
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0249 0.0838 0.3312
Mycobacterium leprae PROBABLE THIOESTERASE TESA 0.0045 0.0101 0.0154
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0249 0.0838 0.3312
Loa Loa (eye worm) hypothetical protein 0.0037 0.0074 0.0183
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0612 0.2143 1
Loa Loa (eye worm) hypothetical protein 0.0205 0.068 0.1734
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0183 0.06 0.1529
Loa Loa (eye worm) hypothetical protein 0.0059 0.0154 0.0387
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.168 0.5989 0.5988
Trypanosoma cruzi target of rapamycin kinase 3 0.0073 0.0202 0.0799
Loa Loa (eye worm) hypothetical protein 0.0028 0.0043 0.0103
Schistosoma mansoni endoplasmin 0.0046 0.0106 0.0106
Schistosoma mansoni smad1 5 8 and 0.0075 0.0211 0.0211
Echinococcus granulosus Protein patched homolog 1 0.0263 0.0886 0.0883
Loa Loa (eye worm) hypothetical protein 0.0037 0.0074 0.0183
Toxoplasma gondii target of rapamycin (TOR), putative 0.0068 0.0185 0.0721
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0033 0.0058 0.0167
Brugia malayi MH1 domain containing protein 0.0042 0.009 0.0224
Mycobacterium ulcerans esterase/lipase LipP 0.0148 0.0473 0.2397
Schistosoma mansoni hypothetical protein 0.0253 0.0852 0.0852
Wolbachia endosymbiont of Brugia malayi thioredoxin reductase 0.0066 0.0179 0.1114
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0126 0.0393 0.0999
Trypanosoma brucei heat shock protein, putative 0.0046 0.0106 0.042
Brugia malayi Niemann-Pick C1 protein precursor 0.0612 0.2143 0.548
Loa Loa (eye worm) hypothetical protein 0.0148 0.0473 0.1205
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0066 0.0179 0.0176
Mycobacterium tuberculosis Probable hydrolase 0.0148 0.0473 0.0726
Onchocerca volvulus 0.0037 0.0074 0.0088
Loa Loa (eye worm) pax transcription factor protein 2 0.0772 0.272 0.6957
Mycobacterium tuberculosis Polyketide synthetase MbtC (polyketide synthase) 0.0018 0.0007 0.0009
Echinococcus multilocularis heat shock protein 90 0.0046 0.0106 0.0104
Loa Loa (eye worm) patched family protein 0.0037 0.0074 0.0183
Mycobacterium tuberculosis Probable polyketide synthase Pks7 0.0057 0.0145 0.0222
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0033 0.0058 0.0229
Trichomonas vaginalis CAMK family protein kinase 0.0398 0.1373 0.6965
Loa Loa (eye worm) isocitrate dehydrogenase 0.0033 0.0058 0.0141
Schistosoma mansoni hypothetical protein 0.0187 0.0616 0.0616
Schistosoma mansoni hypothetical protein 0.0304 0.1034 0.1034
Schistosoma mansoni hypothetical protein 0.0105 0.0319 0.0319
Onchocerca volvulus 0.0037 0.0074 0.0088
Trichomonas vaginalis conserved hypothetical protein 0.0075 0.0211 0.106
Echinococcus multilocularis protein patched 0.0263 0.0886 0.0883
Brugia malayi hypothetical protein 0.0037 0.0074 0.0183
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) 0.008 0.0228 0.0349
Trypanosoma brucei PAB1-binding protein , putative 0.0053 0.0131 0.0516
Entamoeba histolytica heat shock protein 90, putative 0.0046 0.0106 0.0484
Trichomonas vaginalis PIKK family atypical protein kinase 0.0073 0.0202 0.1012
Schistosoma mansoni transcription factor btf3 0.0075 0.0211 0.0211
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0249 0.0838 1
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0059 0.0154 0.0387
Trypanosoma brucei polo-like protein kinase 0.0398 0.1373 0.5426
Toxoplasma gondii patched family protein 0.0037 0.0074 0.0283
Entamoeba histolytica Ran family GTPase 0.0021 0.0016 0.0062
Brugia malayi hypothetical protein 0.0034 0.0063 0.0155
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0066 0.0179 0.0895
Trichomonas vaginalis PIKK family atypical protein kinase 0.0031 0.0051 0.0244
Loa Loa (eye worm) hypothetical protein 0.0037 0.0074 0.0183
Trichomonas vaginalis D-aminoacylase, putative 0.0148 0.0473 0.2391
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0304 0.1034 0.264
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0126 0.0393 0.039
Echinococcus multilocularis sterol regulatory element binding protein 0.0263 0.0886 0.0883
Mycobacterium leprae THIOREDOXIN TRXC (TRX) (MPT46) 0.0066 0.0179 0.0273
Plasmodium vivax type II NADH:ubiquinone oxidoreductase, putative 0.0066 0.0179 0.0648
Onchocerca volvulus 0.0148 0.0473 0.1583
Loa Loa (eye worm) hypothetical protein 0.0049 0.0116 0.0289
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0075 0.0211 0.0211
Leishmania major heat shock protein 83-1 0.0046 0.0106 0.042
Toxoplasma gondii heat shock protein HSP90 0.0046 0.0106 0.041
Mycobacterium ulcerans Type I modular polyketide synthase 0.0054 0.0133 0.0671
Echinococcus granulosus Niemann Pick C1 protein 0.0874 0.3088 0.3086
Mycobacterium leprae Probable NADPH:adrenodoxin oxidoreductase FprA (NADPH-FERREDOXIN REDUCTASE) 0.0066 0.0179 0.0273
Schistosoma mansoni hypothetical protein 0.0049 0.0116 0.0116
Loa Loa (eye worm) PHD-finger family protein 0.0022 0.0021 0.0046
Trichomonas vaginalis PIKK family atypical protein kinase 0.0068 0.0185 0.0926
Loa Loa (eye worm) hypothetical protein 0.0059 0.0154 0.0387
Echinococcus granulosus expressed protein 0.0052 0.0127 0.0125
Leishmania major heat shock protein 83-1 0.0046 0.0106 0.042
Mycobacterium leprae ATP-dependent Clp protease proteolytic subunit 1 0.0028 0.004 0.0059
Loa Loa (eye worm) nuclear hormone receptor 0.0059 0.0154 0.0387
Leishmania major heat shock protein 83-1 0.0046 0.0106 0.042
Echinococcus granulosus endoplasmin 0.0043 0.0096 0.0093
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0038 0.0077 0.0304
Toxoplasma gondii beta-ketoacyl synthase, N-terminal domain-containing protein 0.0035 0.0066 0.0249
Onchocerca volvulus Serine\/threonine kinase homolog 0.0398 0.1373 0.4954
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0126 0.0393 0.0999
Onchocerca volvulus 0.0037 0.0074 0.0088
Loa Loa (eye worm) hypothetical protein 0.0322 0.1098 0.2805
Brugia malayi Patched related family protein 4 0.0037 0.0074 0.0183
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0066 0.0179 0.0895
Wolbachia endosymbiont of Brugia malayi NADPH-dependent glutamate synthase beta chain 0.0066 0.0179 0.1114
Trypanosoma cruzi heat shock protein 85, putative 0.0046 0.0106 0.042
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0033 0.0058 0.0229
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.0125 0.0391 0.0389
Mycobacterium tuberculosis Probable oxidoreductase 0.1824 0.6509 1
Brugia malayi hypothetical protein 0.0059 0.0154 0.0387
Brugia malayi beta-NAC-like protein 0.0075 0.0211 0.0534
Loa Loa (eye worm) hypothetical protein 0.0263 0.0886 0.2261
Entamoeba histolytica pyridine nucleotide-disulfide oxidoreductase family protein 0.0066 0.0179 0.0823
Leishmania major heat shock protein, putative 0.0031 0.0051 0.02
Trypanosoma cruzi transcription factor btf3, putative 0.0075 0.0211 0.0835
Echinococcus granulosus fetal alzheimer antigen falz 0.0024 0.0028 0.0025
Mycobacterium tuberculosis Conserved protein 0.0148 0.0473 0.0726
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0249 0.0838 0.3312
Trichomonas vaginalis PIKK family atypical protein kinase 0.0049 0.0118 0.0584
Brugia malayi ecdysteroid receptor 0.0126 0.0393 0.0999
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.008 0.0228 0.1154
Onchocerca volvulus 0.0148 0.0473 0.1583
Loa Loa (eye worm) patched family protein 0.0037 0.0074 0.0183
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0126 0.0393 0.0999
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.008 0.0228 0.0845
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0249 0.0838 0.3312
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0064 0.017 0.017
Echinococcus multilocularis heat shock protein 0.0046 0.0106 0.0104
Loa Loa (eye worm) hypothetical protein 0.0059 0.0154 0.0387
Echinococcus granulosus histone acetyltransferase KAT2B 0.0142 0.045 0.0448
Trypanosoma cruzi heat shock protein 90, putative 0.0046 0.0106 0.042
Plasmodium falciparum thioredoxin reductase 0.072 0.2531 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0073 0.0202 0.1012
Leishmania major hypothetical protein, conserved 0.0066 0.0179 0.0707
Loa Loa (eye worm) endoplasmin 0.0046 0.0106 0.0265
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.0125 0.0391 0.0389
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0249 0.0838 0.3312
Schistosoma mansoni tar DNA-binding protein 0.0136 0.0431 0.0431
Brugia malayi beta-lactamase family protein 0.0148 0.0473 0.1205
Loa Loa (eye worm) latrophilin receptor protein 2 0.0049 0.0116 0.0289
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0126 0.0393 0.039
Echinococcus granulosus sterol regulatory element binding protein 0.0263 0.0886 0.0883
Loa Loa (eye worm) hypothetical protein 0.0148 0.0473 0.1205
Loa Loa (eye worm) hypothetical protein 0.0037 0.0074 0.0183
Trypanosoma cruzi 2,4-dienoyl-coa reductase fadh1, putative 0.0066 0.0179 0.0707
Schistosoma mansoni hypothetical protein 0.0022 0.0021 0.0021
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.001 0.0036
Echinococcus multilocularis smad 0.0075 0.0211 0.0208
Mycobacterium tuberculosis Possible dehydrogenase/reductase 0.0066 0.0179 0.0273
Echinococcus granulosus histone lysine methyltransferase setb 0.0082 0.0236 0.0234
Brugia malayi MH1 domain containing protein 0.0075 0.0211 0.0533
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0066 0.0179 0.0823
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0091 0.0269 0.0682
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0059 0.0154 0.0151
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsB 0.0043 0.0096 0.048
Echinococcus granulosus geminin 0.1236 0.439 0.4388
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0059 0.0154 0.0151
Echinococcus granulosus Niemann Pick C1 protein 0.0612 0.2143 0.2141
Mycobacterium leprae Polyketide synthase Pks13 0.008 0.0229 0.035
Trypanosoma cruzi polo-like protein kinase, putative 0.0398 0.1373 0.5426
Leishmania major lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative 0.0043 0.0096 0.038
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0064 0.017 0.0168
Mycobacterium tuberculosis Probable thioesterase TesA 0.0045 0.0101 0.0154
Mycobacterium leprae PROBABLE CHAPERONE PROTEIN HTPG (HEAT SHOCK PROTEIN) (HSP90 FAMILY PROTEIN) (HIGH TEMPERATURE PROTEIN G) 0.0043 0.0096 0.0146
Trypanosoma brucei heat shock protein, putative 0.0046 0.0106 0.042
Schistosoma mansoni Smad4 0.0075 0.0211 0.0211
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0045 0.0104 0.0401
Entamoeba histolytica NAD(FAD)-dependent dehydrogenase, putative 0.0066 0.0179 0.0823
Schistosoma mansoni ferritin 0.0052 0.0127 0.0127
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsC 0.0054 0.0133 0.0203
Entamoeba histolytica acetyltransferase, GNAT family 0.0039 0.0082 0.037
Trypanosoma cruzi transcription factor btf3, putative 0.0075 0.0211 0.0835
Trichomonas vaginalis PIKK family atypical protein kinase 0.0049 0.0118 0.0584
Mycobacterium ulcerans NADPH dependent 2,4-dienoyl-CoA reductase FadH 0.0066 0.0179 0.0902
Brugia malayi Patched family protein 0.0037 0.0074 0.0183
Trypanosoma brucei heat shock protein, putative 0.0046 0.0106 0.042
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0945 0.3344 0.5137
Trichomonas vaginalis PIKK family atypical protein kinase 0.0054 0.0135 0.0672
Trypanosoma brucei heat shock protein 84, putative 0.0031 0.0051 0.02
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.008 0.0228 0.0752
Brugia malayi Isocitrate dehydrogenase 0.0033 0.0058 0.0141
Brugia malayi serine/threonine-protein kinase plk-2 0.0398 0.1373 0.3509
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0082 0.0236 0.0236
Trichomonas vaginalis heat shock protein, putative 0.0039 0.0082 0.0405
Loa Loa (eye worm) AMP-binding enzyme family protein 0.005 0.0121 0.0302
Mycobacterium ulcerans bacterioferritin BfrA 0.0052 0.0127 0.0642
Trichomonas vaginalis PIKK family atypical protein kinase 0.0073 0.0202 0.1012
Loa Loa (eye worm) hypothetical protein 0.0037 0.0074 0.0183
Plasmodium falciparum ferrodoxin reductase-like protein 0.0066 0.0179 0.0648
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSA 0.0054 0.0133 0.0203
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0249 0.0838 0.3312
Mycobacterium tuberculosis Bacterioferritin BfrB 0.0052 0.0127 0.0194
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0249 0.0838 0.3312
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0059 0.0154 0.0151
Brugia malayi glutaminase DH11.1 0.0564 0.197 0.5038
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0031 0.0051 0.02
Trypanosoma cruzi importin beta-1 subunit, putative 0.0023 0.0024 0.0093
Toxoplasma gondii non-specific serine/threonine protein kinase 0.0019 0.001 0.0028
Schistosoma mansoni heat shock protein 0.0046 0.0106 0.0106
Brugia malayi isocitrate dehydrogenase 0.0033 0.0058 0.0141
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0066 0.018 0.0177
Echinococcus multilocularis snurportin 1 0.0304 0.1034 0.1032
Plasmodium falciparum ataxin-2 like protein, putative 0.0053 0.0131 0.0456
Plasmodium falciparum heat shock protein 90, putative 0.0027 0.0037 0.0083
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0049 0.0116 0.0113
Onchocerca volvulus Bile acid receptor homolog 0.0126 0.0393 0.1282
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsD 0.0054 0.0133 0.0203
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0028 0.004 0.0095
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprA 0.0066 0.0179 0.0902
Trichomonas vaginalis PIKK family atypical protein kinase 0.0091 0.0269 0.1354
Treponema pallidum oxidoreductase 0.0066 0.0179 0.1742
Loa Loa (eye worm) hypothetical protein 0.0037 0.0074 0.0183
Mycobacterium ulcerans class a beta-lactamase, BlaC 0.0133 0.0421 0.2131
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0033 0.0058 0.0055
Loa Loa (eye worm) hypothetical protein 0.0059 0.0154 0.0387
Trichomonas vaginalis PIKK family atypical protein kinase 0.0031 0.0051 0.0244
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0091 0.0269 0.1063
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0066 0.0179 0.0895
Mycobacterium tuberculosis Probable reductase 0.1641 0.5849 0.8987
Loa Loa (eye worm) patched family protein 0.0037 0.0074 0.0183
Schistosoma mansoni nuclear receptor 0.0059 0.0154 0.0154
Schistosoma mansoni tar DNA-binding protein 0.0136 0.0431 0.0431
Loa Loa (eye worm) hypothetical protein 0.0037 0.0074 0.0183
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0398 0.1373 0.1371
Loa Loa (eye worm) phosphatidylinositol 3 0.0031 0.0051 0.0123
Brugia malayi nuclear receptor NHR-67 0.0059 0.0154 0.0387
Brugia malayi mothers against decapentaplegic homolog 3 0.0034 0.0061 0.015
Schistosoma mansoni hypothetical protein 0.1236 0.439 0.439
Loa Loa (eye worm) hypothetical protein 0.0037 0.0074 0.0183
Mycobacterium ulcerans monoxygenase 0.0066 0.0179 0.0902
Toxoplasma gondii hypothetical protein 0.0028 0.004 0.0146
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0031 0.0051 0.0123
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0091 0.0269 0.1245
Trypanosoma brucei NADH dehydrogenase 0.0066 0.0179 0.0707
Wolbachia endosymbiont of Brugia malayi bacterioferritin/cytochrome b1 0.0052 0.0127 0.0421
Schistosoma mansoni hypothetical protein 0.0066 0.0179 0.0179
Brugia malayi CHE-14 protein 0.0263 0.0886 0.2261
Loa Loa (eye worm) hypothetical protein 0.0037 0.0074 0.0183
Brugia malayi Pre-SET motif family protein 0.0445 0.1542 0.3939
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.008 0.0228 0.0893
Brugia malayi TAR-binding protein 0.0136 0.0431 0.1097
Mycobacterium tuberculosis Probable thioredoxin reductase TrxB2 (TRXR) (TR) 0.0066 0.0179 0.0273
Leishmania major heat shock protein 83-1 0.0046 0.0106 0.042
Trichomonas vaginalis D-aminoacylase, putative 0.0148 0.0473 0.2391
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0249 0.0838 0.3312
Entamoeba histolytica heat shock transcription factor, putative 0.0205 0.068 0.3165
Schistosoma mansoni glutamate synthase 0.0066 0.0179 0.0179
Mycobacterium leprae Probable NADH-dependent glutamate synthase (small subunit) GltD (L-glutamate synthase) (L-glutamate synthetase) (NADH-glutamate 0.0066 0.0179 0.0273
Brugia malayi tailless protein 0.0059 0.0154 0.0387
Plasmodium vivax heat shock protein 86, putative 0.0046 0.0106 0.0359
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0126 0.0393 0.039
Loa Loa (eye worm) patched family protein 0.0037 0.0074 0.0183
Plasmodium vivax SET domain protein, putative 0.0064 0.017 0.0613
Toxoplasma gondii hypothetical protein 0.0037 0.0074 0.0283
Trypanosoma cruzi hypothetical protein, conserved 0.0148 0.0473 0.187
Loa Loa (eye worm) hypothetical protein 0.009 0.0264 0.067
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0091 0.0269 0.1063
Brugia malayi Thioredoxin reductase 0.072 0.2531 0.6472
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0126 0.0393 0.0999
Loa Loa (eye worm) hypothetical protein 0.008 0.0228 0.0578
Schistosoma mansoni apoferritin-2 0.0052 0.0127 0.0127
Onchocerca volvulus 0.0037 0.0074 0.0088
Brugia malayi Patched family protein 0.0037 0.0074 0.0183
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0033 0.0058 0.0167
Trichomonas vaginalis glutaminase, putative 0.0564 0.197 1
Loa Loa (eye worm) hypothetical protein 0.0066 0.0179 0.0451
Plasmodium vivax NAD(P)H-dependent glutamate synthase, putative 0.0066 0.0179 0.0648
Giardia lamblia Glutamate synthase 0.0066 0.0179 0.12
Onchocerca volvulus Protein patched homolog 0.0037 0.0074 0.0088
Loa Loa (eye worm) hypothetical protein 0.0037 0.0074 0.0183
Plasmodium falciparum basic transcription factor 3b, putative 0.0075 0.0211 0.0777
Brugia malayi beta-lactamase 0.0148 0.0473 0.1205
Brugia malayi nuclear hormone receptor family member nhr-6 0.0059 0.0154 0.0387
Echinococcus multilocularis GPCR, family 2 0.0049 0.0116 0.0113
Leishmania major importin beta-1 subunit, putative 0.0023 0.0024 0.0093
Loa Loa (eye worm) hypothetical protein 0.0037 0.0074 0.0183
Brugia malayi RNA binding protein 0.0136 0.0431 0.1097
Brugia malayi Probable ClpP-like protease 0.008 0.0228 0.0578
Mycobacterium ulcerans thioesterase TesA 0.0045 0.0101 0.0508
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0091 0.0269 0.1063
Mycobacterium leprae PROBABLE CONSERVED LIPOPROTEIN LPQF 0.0064 0.0171 0.0261
Plasmodium vivax importin-beta 2, putative 0.0028 0.0043 0.0108
Brugia malayi Nuclear hormone receptor-like 1 0.0126 0.0393 0.0999
Echinococcus multilocularis mothers against decapentaplegic 2 0.0034 0.0061 0.0059
Echinococcus granulosus apoptosis inducing factor 1 mitochondrial 0.0066 0.0179 0.0176
Toxoplasma gondii Hsp90 domain-containing protein 0.0175 0.0569 0.224
Loa Loa (eye worm) hypothetical protein 0.0037 0.0074 0.0183
Brugia malayi MH2 domain containing protein 0.0075 0.0211 0.0533
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0066 0.0179 0.0451
Schistosoma mansoni ferritin 0.0052 0.0127 0.0127
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.1824 0.6509 1
Entamoeba histolytica dihydropyrimidine dehydrogenase, putative 0.0066 0.0179 0.0823
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.008 0.0228 0.0893
Schistosoma mansoni ferritin light chain 0.0052 0.0127 0.0127
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0031 0.0051 0.02
Echinococcus multilocularis importin subunit beta 1 0.0028 0.0043 0.004
Plasmodium vivax patched family protein, putative 0.0037 0.0074 0.0231
Echinococcus granulosus pyridine nucleotide disulfide oxidoreductase 0.0066 0.0179 0.0176
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0031 0.0051 0.02
Trichomonas vaginalis PIKK family atypical protein kinase 0.0055 0.0137 0.0682
Echinococcus granulosus zinc finger protein 0.0025 0.0029 0.0027
Echinococcus multilocularis Niemann Pick C1 protein 0.0612 0.2143 0.2141
Trichomonas vaginalis PIKK family atypical protein kinase 0.0049 0.0118 0.0586
Plasmodium falciparum type II NADH:ubiquinone oxidoreductase 0.0066 0.0179 0.0648
Trichomonas vaginalis PIKK family atypical protein kinase 0.0055 0.0137 0.0682
Mycobacterium ulcerans polyketide synthase 0.0057 0.0145 0.0732
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.008 0.0228 0.0752
Brugia malayi HSF-type DNA-binding domain containing protein 0.0205 0.068 0.1734
Toxoplasma gondii NADH dehydrogenase (NDH2-II) 0.0066 0.0179 0.0697
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0148 0.0473 0.0726
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0039 0.008 0.0077
Echinococcus multilocularis mothers against decapentaplegic 5 0.0075 0.0211 0.0208
Loa Loa (eye worm) hypothetical protein 0.0037 0.0074 0.0183
Echinococcus granulosus smad 0.0075 0.0211 0.0208
Mycobacterium ulcerans multifunctional mycocerosic acid synthase membrane-associated Mas 0.0057 0.0145 0.0732
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0066 0.0179 0.0697
Echinococcus granulosus tar DNA binding protein 0.0136 0.0431 0.0428
Plasmodium vivax thioredoxin reductase, putative 0.072 0.2531 1
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0249 0.0838 0.425
Mycobacterium tuberculosis Probable polyketide synthase Pks8 0.0044 0.0098 0.0149
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0249 0.0838 0.425
Loa Loa (eye worm) beta-lactamase 0.0148 0.0473 0.1205
Brugia malayi Patched family protein 0.0037 0.0074 0.0183
Loa Loa (eye worm) hypothetical protein 0.0126 0.0393 0.0999
Echinococcus granulosus thioredoxin glutathione reductase 0.0723 0.2542 0.254
Schistosoma mansoni nuclear hormone receptor 0.0059 0.0154 0.0154
Loa Loa (eye worm) hypothetical protein 0.0037 0.0074 0.0183
Schistosoma mansoni endoplasmin 0.0046 0.0106 0.0106
Loa Loa (eye worm) hypothetical protein 0.0037 0.0074 0.0183
Loa Loa (eye worm) hypothetical protein 0.0037 0.0074 0.0183
Onchocerca volvulus Heat shock factor protein 2 homolog 0.0205 0.068 0.2358
Trichomonas vaginalis importin beta-1, putative 0.0023 0.0024 0.0106
Schistosoma mansoni retinoic acid receptor RXR 0.0126 0.0393 0.0393
Trichomonas vaginalis conserved hypothetical protein 0.0263 0.0886 0.4488
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0249 0.0838 0.3312
Leishmania major heat shock protein 83-1 0.0046 0.0106 0.042
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0126 0.0393 0.039
Loa Loa (eye worm) hypothetical protein 0.0126 0.0393 0.0999
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0249 0.0838 0.3312
Mycobacterium tuberculosis Probable polyketide synthase Pks15 0.0022 0.0019 0.0027
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0398 0.1373 0.1371
Brugia malayi latrophilin 2 splice variant baaae 0.0105 0.0319 0.081
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0091 0.0269 0.1063
Brugia malayi glutathione reductase 0.072 0.2531 0.6472
Mycobacterium tuberculosis Polyketide synthase Pks2 0.0052 0.0127 0.0194
Echinococcus granulosus methyl CpG binding domain protein 2 0.0018 0.0007 0.0004
Onchocerca volvulus 0.0037 0.0074 0.0088
Loa Loa (eye worm) hypothetical protein 0.0053 0.0131 0.0327
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0033 0.0058 0.0229
Plasmodium falciparum heat shock protein 90, putative 0.0175 0.0569 0.2199
Trypanosoma brucei hypothetical protein, conserved 0.0148 0.0473 0.187
Mycobacterium leprae Probable lipase LipE 0.0148 0.0473 0.0726
Leishmania major heat shock protein 83-1 0.0046 0.0106 0.042
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0148 0.0473 0.1205
Trypanosoma brucei importin beta-1 subunit, putative 0.0028 0.0043 0.017
Plasmodium falciparum importin beta, putative 0.0028 0.0043 0.0108
Echinococcus granulosus ecdysone induced protein 78C 0.0126 0.0393 0.039
Trypanosoma brucei heat shock protein 90, putative 0.0046 0.0106 0.042
Plasmodium vivax heat shock protein 90, putative 0.0031 0.0051 0.0138
Brugia malayi Beta-ketoacyl synthase, N-terminal domain containing protein 0.0054 0.0133 0.0334
Plasmodium vivax ferrodoxin reductase, putative 0.0066 0.0179 0.0648
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0066 0.0179 0.0823
Trichomonas vaginalis PIKK family atypical protein kinase 0.0068 0.0185 0.0926
Trypanosoma brucei heat shock protein, putative 0.0046 0.0106 0.042
Loa Loa (eye worm) hypothetical protein 0.0154 0.0494 0.1258
Mycobacterium tuberculosis Class a beta-lactamase BlaC 0.0133 0.0421 0.0645
Trichomonas vaginalis heat shock protein, putative 0.0033 0.0061 0.0296
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0021 0.0016 0.0034
Brugia malayi hypothetical protein 0.0037 0.0074 0.0183
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0049 0.0116 0.0289
Mycobacterium ulcerans hypothetical protein 0.0148 0.0473 0.2397
Schistosoma mansoni smad 0.0075 0.0211 0.0211
Trichomonas vaginalis PIKK family atypical protein kinase 0.0068 0.0185 0.0926
Onchocerca volvulus 0.0064 0.017 0.0448
Leishmania major hypothetical protein, conserved 0.0066 0.0179 0.0707
Echinococcus granulosus beta LACTamase domain containing family member 0.0148 0.0473 0.0471
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0066 0.0179 0.0895
Trypanosoma brucei importin beta-1 subunit, putative 0.0028 0.0043 0.017
Brugia malayi Nuclear hormone receptor-like 1 0.0066 0.018 0.0453
Brugia malayi Hsp90 protein 0.0031 0.0051 0.0123
Brugia malayi hypothetical protein 0.0053 0.0131 0.0327
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0059 0.0154 0.0151
Loa Loa (eye worm) RNA binding protein 0.0136 0.0431 0.1097
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprB 0.0066 0.0179 0.0902
Leishmania major heat shock protein 83-1 0.0046 0.0106 0.042
Mycobacterium tuberculosis Probable membrane bound polyketide synthase Pks6 0.008 0.0229 0.035
Loa Loa (eye worm) nuclear factor I 0.0042 0.009 0.0224
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0249 0.0838 0.3312
Mycobacterium tuberculosis Probable NADH-dependent glutamate synthase (small subunit) GltD (L-glutamate synthase) (L-glutamate synthetase) (NADH-glutamate 0.0066 0.0179 0.0273
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0249 0.0838 0.0836
Loa Loa (eye worm) hypothetical protein 0.0037 0.0074 0.0183
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0045 0.0104 0.035
Echinococcus multilocularis sulfide:quinone oxidoreductase 0.0066 0.0179 0.0176
Onchocerca volvulus 0.0148 0.0473 0.1583
Mycobacterium ulcerans glutaminase 0.0564 0.197 1
Loa Loa (eye worm) hypothetical protein 0.0041 0.009 0.0223
Loa Loa (eye worm) hypothetical protein 0.0034 0.0061 0.015
Leishmania major NADH dehydrogenase, putative 0.0066 0.0179 0.0707
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0082 0.0236 0.0234
Loa Loa (eye worm) steroid hormone receptor 0.0126 0.0393 0.0999
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0144 0.0457 0.0455
Plasmodium falciparum lipid/sterol:H+ symporter 0.0037 0.0074 0.0231
Trypanosoma brucei Heat shock protein 83, putative 0.0046 0.0106 0.042
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0043 0.0096 0.0379
Loa Loa (eye worm) MH1 domain-containing protein 0.0034 0.0061 0.015
Toxoplasma gondii heat shock protein 75, putative 0.0031 0.0051 0.019
Schistosoma mansoni Smad4 0.0034 0.0061 0.0061
Schistosoma mansoni smad1 5 8 and 0.0075 0.0211 0.0211
Mycobacterium leprae conserved hypothetical protein 0.0148 0.0473 0.0726
Brugia malayi hypothetical protein 0.0066 0.018 0.0453
Loa Loa (eye worm) hypothetical protein 0.0148 0.0473 0.1205
Trypanosoma brucei heat shock protein, putative 0.0046 0.0106 0.042
Giardia lamblia Heat shock protein HSP 90-alpha 0.0039 0.0082 0.049
Loa Loa (eye worm) helix-loop-helix DNA-binding domain-containing protein 0.0114 0.035 0.0888
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0144 0.0457 0.0457
Schistosoma mansoni cellular tumor antigen P53 0.01 0.0302 0.0302
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0064 0.017 0.017
Loa Loa (eye worm) hypothetical protein 0.0048 0.0112 0.0279
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0126 0.0393 0.0999
Mycobacterium ulcerans Type I modular polyketide synthase 0.0054 0.0133 0.0671
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0066 0.0179 0.0707
Loa Loa (eye worm) hypothetical protein 0.003 0.0049 0.0117
Entamoeba histolytica hypothetical protein 0.0075 0.0211 0.0974
Plasmodium falciparum glutathione reductase 0.0249 0.0838 0.3269
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0024 0.0106
Entamoeba histolytica 90 kDa heat shock protein, putative 0.0031 0.0051 0.0224
Schistosoma mansoni methyl-cpg binding protein mbd 0.0018 0.0007 0.0007
Trypanosoma cruzi NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0066 0.0179 0.0707
Mycobacterium ulcerans NADH dehydrogenase Ndh1 0.0066 0.0179 0.0902
Brugia malayi nuclear hormone receptor 0.0059 0.0154 0.0387
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0249 0.0838 0.1286
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0621 0.2177 0.2177
Mycobacterium tuberculosis Probable polyketide synthase Pks9 0.003 0.005 0.0075
Loa Loa (eye worm) hypothetical protein 0.0042 0.009 0.0224
Trichomonas vaginalis PIKK family atypical protein kinase 0.0031 0.0051 0.0244
Echinococcus multilocularis heat shock protein 90 0.0039 0.0082 0.008
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0126 0.0393 0.0999
Loa Loa (eye worm) hypothetical protein 0.0037 0.0074 0.0183
Brugia malayi Patched related family protein 12 0.0037 0.0074 0.0183
Trichomonas vaginalis CAMK family protein kinase 0.0398 0.1373 0.6965
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0045 0.0104 0.0515
Echinococcus multilocularis tumor protein p63 0.0686 0.2411 0.2409
Echinococcus granulosus muscleblind protein 0.0147 0.0471 0.0469
Plasmodium falciparum endoplasmin, putative 0.0033 0.0061 0.0179
Schistosoma mansoni ataxia telangiectasia mutated (atm) 0.0017 0.0003 0.0003
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0126 0.0393 0.0999
Brugia malayi beta-lactamase family protein 0.0148 0.0473 0.1205
Trichomonas vaginalis conserved hypothetical protein 0.0075 0.0211 0.106
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0126 0.0393 0.039
Leishmania major hypothetical protein, conserved 0.0066 0.0179 0.0707
Echinococcus multilocularis nuclear receptor nhr 48 0.0059 0.0154 0.0151
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.1641 0.5849 0.8987
Giardia lamblia Glycerol-3-phosphate dehydrogenase 0.0066 0.0179 0.12
Schistosoma mansoni transcription factor LCR-F1 0.0187 0.0616 0.0616
Brugia malayi Patched family protein 0.0037 0.0074 0.0183
Brugia malayi Patched protein homolog 1 0.0037 0.0074 0.0183
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0029 0.0132
Onchocerca volvulus Mothers against decapentaplegic homolog 0.0034 0.0061 0.004
Brugia malayi Importin beta-1 subunit 0.0028 0.0043 0.0103
Echinococcus multilocularis transcription factor btf3 0.0075 0.0211 0.0209
Trichomonas vaginalis mercuric reductase, putative 0.0249 0.0838 0.4246
Schistosoma mansoni thyroid hormone receptor 0.0251 0.0844 0.0844
Loa Loa (eye worm) hypothetical protein 0.0019 0.0008 0.0012
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSE 0.0035 0.0068 0.0103
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0033 0.0058 0.0229
Loa Loa (eye worm) hypothetical protein 0.0037 0.0074 0.0183
Loa Loa (eye worm) acyl carrier protein 0.0025 0.0029 0.0068
Schistosoma mansoni fkbp-rapamycin associated protein 0.0017 0.0003 0.0003
Schistosoma mansoni glutamate synthase 0.0066 0.0179 0.0179
Brugia malayi PHD-finger family protein 0.003 0.005 0.0122
Trichomonas vaginalis glutamate synthase, putative 0.0066 0.0179 0.0895
Loa Loa (eye worm) hypothetical protein 0.0037 0.0074 0.0183
Echinococcus multilocularis beta LACTamase domain containing family member 0.0148 0.0473 0.0471
Mycobacterium ulcerans polyketide synthase 0.0054 0.0133 0.0671
Schistosoma mansoni kinase 0.0202 0.0669 0.0669
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0059 0.0154 0.0151
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0091 0.0269 0.1245
Trichomonas vaginalis glutamate synthase, putative 0.0066 0.0179 0.0895
Brugia malayi Myosin head containing protein 0.0037 0.0074 0.0183
Brugia malayi Pax transcription factor protein 2 0.0772 0.272 0.6957
Trichomonas vaginalis D-aminoacylase, putative 0.0148 0.0473 0.2391
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0073 0.0202 0.0799
Trichomonas vaginalis bromodomain-containing protein, putative 0.0045 0.0104 0.0515
Mycobacterium tuberculosis Probable chaperone protein HtpG (heat shock protein) (HSP90 family protein) (high temperature protein G) 0.0043 0.0096 0.0146
Schistosoma mansoni heat shock protein 0.0046 0.0106 0.0106
Schistosoma mansoni hypothetical protein 0.0024 0.0026 0.0026
Onchocerca volvulus Fatty acid synthase homolog 0.0097 0.0288 0.0889
Trypanosoma brucei beta lactamase 0.0064 0.0171 0.0676
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0066 0.0179 0.0451
Echinococcus granulosus heat shock protein 90 0.0046 0.0106 0.0104
Brugia malayi nuclear receptor NHR-88 0.0126 0.0393 0.0999
Echinococcus granulosus ferritin 0.0052 0.0127 0.0125
Loa Loa (eye worm) hypothetical protein 0.0126 0.0393 0.0999
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0021 0.0016 0.0052
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0066 0.018 0.0453
Giardia lamblia Histone acetyltransferase GCN5 0.0039 0.0082 0.0486
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.008 0.0228 0.1154
Mycobacterium tuberculosis Probable lipase LipD 0.0148 0.0473 0.0726
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.1824 0.6509 1
Loa Loa (eye worm) thioredoxin reductase 0.072 0.2531 0.6472
Echinococcus granulosus Nuclear hormone receptor HR96 0.0059 0.0154 0.0151
Loa Loa (eye worm) hypothetical protein 0.0059 0.0154 0.0387
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0091 0.0269 0.0266
Loa Loa (eye worm) glutaminase 2 0.0564 0.197 0.5038
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0066 0.0179 0.0895
Schistosoma mansoni importin beta-1 0.0028 0.0043 0.0043
Brugia malayi Nuclear hormone receptor E75 0.0059 0.0154 0.0387
Schistosoma mansoni nuclear hormone receptor 0.0126 0.0393 0.0393
Mycobacterium ulcerans thioredoxin reductase TrxB2 0.0066 0.0179 0.0902
Plasmodium falciparum ataxin-2 like protein, putative 0.0053 0.0131 0.0456
Brugia malayi Patched family protein 0.0037 0.0074 0.0183
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0144 0.0457 0.0455
Brugia malayi Patched family protein 0.0037 0.0074 0.0183
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0126 0.0393 0.039
Loa Loa (eye worm) hypothetical protein 0.0059 0.0154 0.0387
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0024 0.0026 0.0023
Onchocerca volvulus 0.0037 0.0074 0.0088
Toxoplasma gondii HEAT repeat-containing protein 0.0028 0.0043 0.0159
Treponema pallidum NADH oxidase 0.0249 0.0838 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0073 0.0202 0.1012
Trypanosoma cruzi heat shock protein, putative 0.0031 0.0051 0.02
Trypanosoma cruzi heat shock protein 85, putative 0.0039 0.0082 0.0326
Echinococcus multilocularis pyridine nucleotide disulfide oxidoreductase 0.0066 0.0179 0.0176
Toxoplasma gondii heat shock protein 90, putative 0.0046 0.0106 0.041
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0126 0.0393 0.0999
Schistosoma mansoni hypothetical protein 0.0049 0.0116 0.0116
Loa Loa (eye worm) bromodomain containing protein 0.0023 0.0022 0.005
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0144 0.0457 0.0457
Trypanosoma cruzi Heat shock protein 83, putative 0.0046 0.0106 0.042
Leishmania major heat shock protein 83-1 0.0046 0.0106 0.042
Echinococcus granulosus TGF beta signal transducer SmadC 0.0075 0.0211 0.0208
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0144 0.0457 0.1164
Brugia malayi ecdysone receptor 0.0059 0.0154 0.0387

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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