Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.0113 | 0.1237 | 0.4136 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0025 | 0.0085 | 0.1066 |
Loa Loa (eye worm) | hypothetical protein | 0.0245 | 0.296 | 1 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0035 | 0.0209 | 0.2626 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0028 | 0.012 | 0.1507 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0028 | 0.0116 | 0.1461 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0035 | 0.0209 | 0.2626 |
Schistosoma mansoni | hypothetical protein | 0.0052 | 0.0442 | 0.0442 |
Schistosoma mansoni | chromobox protein | 0.0072 | 0.07 | 0.07 |
Onchocerca volvulus | 0.008 | 0.0795 | 1 | |
Onchocerca volvulus | 0.008 | 0.0795 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.0171 | 0.0506 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0047 | 0.0376 | 0.1055 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.0508 | 0.6396 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0029 | 0.0131 | 0.1643 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.008 | 0.0795 | 0.2632 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0037 | 0.024 | 0.3021 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0035 | 0.0209 | 0.2626 |
Echinococcus multilocularis | GPCR, family 2 | 0.0052 | 0.0442 | 0.0442 |
Echinococcus multilocularis | tumor protein p63 | 0.0384 | 0.4772 | 0.4772 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0128 | 0.1424 | 0.4772 |
Echinococcus granulosus | survival motor neuron protein 1 | 0.0245 | 0.296 | 0.296 |
Echinococcus multilocularis | tar DNA binding protein | 0.0137 | 0.155 | 0.155 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.008 | 0.0795 | 1 |
Trichomonas vaginalis | ap endonuclease, putative | 0.002 | 0.0022 | 0.0279 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0277 | 0.3373 | 0.3373 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0047 | 0.0376 | 0.0376 |
Trypanosoma brucei | target of rapamycin kinase 3, putative | 0.0037 | 0.0241 | 0.2948 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.008 | 0.0795 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.008 | 0.0795 | 0.2632 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.008 | 0.0795 | 0.0795 |
Mycobacterium tuberculosis | Probable lipase LipE | 0.008 | 0.0795 | 0.1244 |
Mycobacterium ulcerans | lipase LipD | 0.008 | 0.0795 | 1 |
Echinococcus multilocularis | FKBP12 rapamycin complex associated protein | 0.0047 | 0.0365 | 0.0365 |
Trypanosoma brucei | Phosphatidylinositol 3-kinase tor1 | 0.0047 | 0.0365 | 0.4526 |
Trypanosoma cruzi | Phosphatidylinositol 3-kinase tor2 | 0.0047 | 0.0365 | 0.4432 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0047 | 0.0365 | 0.4587 |
Loa Loa (eye worm) | phosphatidylinositol 3 | 0.0047 | 0.0365 | 0.1167 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0137 | 0.155 | 0.5202 |
Trichomonas vaginalis | chromobox protein, putative | 0.0072 | 0.07 | 0.88 |
Echinococcus multilocularis | chromobox protein 1 | 0.0072 | 0.07 | 0.07 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0052 | 0.0442 | 0.0442 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0035 | 0.0209 | 0.2626 |
Echinococcus multilocularis | DNA (apurinic or apyrimidinic site) lyase | 0.002 | 0.0022 | 0.0022 |
Leishmania major | target of rapamycin kinase (TOR) kinase 3 | 0.0037 | 0.0241 | 0.2828 |
Onchocerca volvulus | Heterochromatin protein 1 homolog | 0.0044 | 0.0325 | 0.2473 |
Plasmodium falciparum | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.002 | 0.0022 | 0.5 |
Schistosoma mansoni | tar DNA-binding protein | 0.0137 | 0.155 | 0.155 |
Wolbachia endosymbiont of Brugia malayi | exonuclease III | 0.002 | 0.0022 | 1 |
Loa Loa (eye worm) | RNA binding protein | 0.0137 | 0.155 | 0.5202 |
Brugia malayi | RNA binding protein | 0.0137 | 0.155 | 0.456 |
Trypanosoma cruzi | target of rapamycin kinase 3 | 0.0037 | 0.0241 | 0.2828 |
Schistosoma mansoni | tar DNA-binding protein | 0.0137 | 0.155 | 0.155 |
Entamoeba histolytica | hypothetical protein | 0.0277 | 0.3373 | 1 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0052 | 0.0442 | 0.1252 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0037 | 0.024 | 0.3021 |
Schistosoma mansoni | ap endonuclease | 0.002 | 0.0022 | 0.0022 |
Mycobacterium leprae | conserved hypothetical protein | 0.008 | 0.0795 | 1 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0025 | 0.0085 | 0.1066 |
Schistosoma mansoni | hypothetical protein | 0.0277 | 0.3373 | 0.3373 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.0285 | 0.0895 |
Mycobacterium ulcerans | hypothetical protein | 0.008 | 0.0795 | 1 |
Mycobacterium tuberculosis | Conserved protein | 0.008 | 0.0795 | 0.1244 |
Mycobacterium tuberculosis | Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) | 0.002 | 0.0022 | 0.0035 |
Toxoplasma gondii | ABC1 family protein | 0.008 | 0.0795 | 1 |
Brugia malayi | hypothetical protein | 0.0277 | 0.3373 | 1 |
Mycobacterium tuberculosis | Possible conserved lipoprotein LpqK | 0.008 | 0.0795 | 0.1244 |
Schistosoma mansoni | ap endonuclease | 0.002 | 0.0022 | 0.0022 |
Echinococcus granulosus | FKBP12 rapamycin complex associated protein | 0.0047 | 0.0365 | 0.0365 |
Leishmania major | target of rapamycin (TOR) kinase 2, putative | 0.0047 | 0.0365 | 0.4432 |
Schistosoma mansoni | survival motor neuron protein | 0.005 | 0.0409 | 0.0409 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.008 | 0.0795 | 1 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0052 | 0.0442 | 0.0442 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0025 | 0.0085 | 0.1066 |
Schistosoma mansoni | hypothetical protein | 0.0052 | 0.0442 | 0.0442 |
Giardia lamblia | GTOR | 0.0047 | 0.0365 | 1 |
Echinococcus multilocularis | microtubule associated protein 2 | 0.0784 | 1 | 1 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0047 | 0.0376 | 0.1204 |
Mycobacterium ulcerans | exodeoxyribonuclease III protein XthA | 0.002 | 0.0022 | 0.0279 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0052 | 0.0442 | 0.1428 |
Brugia malayi | MH2 domain containing protein | 0.0128 | 0.1424 | 0.4183 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0166 | 0.1923 | 0.5671 |
Trypanosoma cruzi | Phosphatidylinositol 3-kinase tor1 | 0.0047 | 0.0365 | 0.4432 |
Echinococcus granulosus | tar DNA binding protein | 0.0137 | 0.155 | 0.155 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0037 | 0.024 | 0.3021 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0028 | 0.012 | 0.1507 |
Schistosoma mansoni | hypothetical protein | 0.0113 | 0.1237 | 0.1237 |
Onchocerca volvulus | 0.005 | 0.0409 | 0.3821 | |
Schistosoma mansoni | hypothetical protein | 0.0052 | 0.0442 | 0.0442 |
Echinococcus granulosus | DNA apurinic or apyrimidinic site lyase | 0.002 | 0.0022 | 0.0022 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0166 | 0.1923 | 0.5671 |
Echinococcus granulosus | GPCR family 2 | 0.0052 | 0.0442 | 0.0442 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0052 | 0.0442 | 0.1252 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0035 | 0.0209 | 0.2626 |
Trichomonas vaginalis | chromobox protein, putative | 0.0044 | 0.0325 | 0.409 |
Trichomonas vaginalis | ap endonuclease, putative | 0.002 | 0.0022 | 0.0279 |
Entamoeba histolytica | FKBP-rapamycin associated protein (FRAP), putative | 0.0047 | 0.0365 | 0.1023 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0047 | 0.0365 | 0.4587 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0047 | 0.0376 | 0.0376 |
Loa Loa (eye worm) | beta-lactamase | 0.008 | 0.0795 | 0.2632 |
Mycobacterium tuberculosis | Probable conserved lipoprotein | 0.008 | 0.0795 | 0.1244 |
Loa Loa (eye worm) | hypothetical protein | 0.008 | 0.0795 | 0.2632 |
Mycobacterium tuberculosis | Conserved protein | 0.008 | 0.0795 | 0.1244 |
Brugia malayi | beta-lactamase | 0.008 | 0.0795 | 0.2307 |
Loa Loa (eye worm) | TAR-binding protein | 0.0137 | 0.155 | 0.5202 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0025 | 0.0084 | 0.106 |
Onchocerca volvulus | 0.0056 | 0.049 | 0.5114 | |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0028 | 0.012 | 0.1507 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0052 | 0.0442 | 0.0442 |
Schistosoma mansoni | tar DNA-binding protein | 0.0137 | 0.155 | 0.155 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.003 | 0.0151 | 0.1902 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.0442 | 0.1428 |
Loa Loa (eye worm) | hypothetical protein | 0.0166 | 0.1923 | 0.647 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.008 | 0.0795 | 1 |
Schistosoma mansoni | hypothetical protein | 0.005 | 0.0409 | 0.0409 |
Trichomonas vaginalis | conserved hypothetical protein | 0.004 | 0.0285 | 0.3585 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0277 | 0.3373 | 0.3373 |
Treponema pallidum | exodeoxyribonuclease (exoA) | 0.002 | 0.0022 | 1 |
Schistosoma mansoni | ataxia telangiectasia mutated (atm)-related | 0.0047 | 0.0365 | 0.0365 |
Mycobacterium tuberculosis | Probable esterase/lipase LipP | 0.008 | 0.0795 | 0.1244 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0128 | 0.1424 | 0.4772 |
Mycobacterium ulcerans | esterase/lipase LipP | 0.008 | 0.0795 | 1 |
Brugia malayi | beta-lactamase family protein | 0.008 | 0.0795 | 0.2307 |
Entamoeba histolytica | hypothetical protein | 0.0277 | 0.3373 | 1 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0025 | 0.0085 | 0.1066 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0035 | 0.0209 | 0.2626 |
Brugia malayi | TAR-binding protein | 0.0137 | 0.155 | 0.456 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0137 | 0.155 | 0.456 |
Trichomonas vaginalis | conserved hypothetical protein | 0.004 | 0.0285 | 0.3585 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.008 | 0.0795 | 0.0795 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.008 | 0.0795 | 1 |
Brugia malayi | Iron-sulfur cluster assembly accessory protein | 0.005 | 0.0409 | 0.1156 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0025 | 0.0084 | 0.106 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0047 | 0.0376 | 0.0376 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.008 | 0.0795 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0047 | 0.0376 | 0.0376 |
Loa Loa (eye worm) | hypothetical protein | 0.008 | 0.0795 | 0.2632 |
Entamoeba histolytica | phosphatidylinositol3-kinaseTor2, putative | 0.0047 | 0.0365 | 0.1023 |
Echinococcus multilocularis | survival motor neuron protein 1 | 0.0245 | 0.296 | 0.296 |
Trichomonas vaginalis | chromobox protein, putative | 0.0072 | 0.07 | 0.88 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0028 | 0.0116 | 0.1461 |
Brugia malayi | hypothetical protein | 0.0245 | 0.296 | 0.8766 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0035 | 0.0209 | 0.2626 |
Leishmania major | hypothetical protein, conserved | 0.008 | 0.0795 | 1 |
Loa Loa (eye worm) | heterochromatin protein 1 | 0.0072 | 0.07 | 0.2307 |
Mycobacterium tuberculosis | Probable esterase LipL | 0.008 | 0.0795 | 0.1244 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0166 | 0.1923 | 0.647 |
Entamoeba histolytica | hypothetical protein | 0.0277 | 0.3373 | 1 |
Mycobacterium ulcerans | fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE | 0.008 | 0.0795 | 1 |
Schistosoma mansoni | microtubule-associated protein tau | 0.0784 | 1 | 1 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0037 | 0.024 | 0.3021 |
Echinococcus multilocularis | chromobox protein 1 | 0.0072 | 0.07 | 0.07 |
Trichomonas vaginalis | esterase, putative | 0.008 | 0.0795 | 1 |
Trichomonas vaginalis | chromobox protein, putative | 0.0044 | 0.0325 | 0.409 |
Mycobacterium leprae | Probable lipase LipE | 0.008 | 0.0795 | 1 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0113 | 0.1237 | 0.3626 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0047 | 0.0376 | 0.0376 |
Leishmania major | target of rapamycin (TOR) kinase 1, putative | 0.0047 | 0.0365 | 0.4432 |
Schistosoma mansoni | tar DNA-binding protein | 0.0137 | 0.155 | 0.155 |
Echinococcus granulosus | chromobox protein 1 | 0.0072 | 0.07 | 0.07 |
Schistosoma mansoni | cellular tumor antigen P53 | 0.0056 | 0.049 | 0.049 |
Plasmodium vivax | hypothetical protein, conserved | 0.008 | 0.0795 | 1 |
Onchocerca volvulus | Heterochromatin protein 1 homolog | 0.004 | 0.0285 | 0.183 |
Onchocerca volvulus | 0.008 | 0.0795 | 1 | |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0031 | 0.0164 | 0.2067 |
Trypanosoma brucei | apurinic/apyrimidinic endonuclease, putative | 0.002 | 0.0022 | 0.0168 |
Mycobacterium tuberculosis | Probable hydrolase | 0.008 | 0.0795 | 0.1244 |
Schistosoma mansoni | hypothetical protein | 0.0052 | 0.0442 | 0.0442 |
Brugia malayi | Phosphatidylinositol 3- and 4-kinase family protein | 0.0047 | 0.0365 | 0.1023 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0029 | 0.0131 | 0.1643 |
Trypanosoma brucei | hypothetical protein, conserved | 0.008 | 0.0795 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0056 | 0.049 | 0.1593 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0047 | 0.0376 | 0.0376 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0047 | 0.0376 | 0.0376 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0037 | 0.024 | 0.3021 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0052 | 0.0442 | 0.0442 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.008 | 0.0795 | 0.2307 |
Toxoplasma gondii | target of rapamycin (TOR), putative | 0.0035 | 0.0209 | 0.2415 |
Loa Loa (eye worm) | hypothetical protein | 0.008 | 0.0795 | 0.2632 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.004 | 0.0276 | 0.3468 |
Brugia malayi | chromobox protein homolog 3 | 0.004 | 0.0285 | 0.0785 |
Trypanosoma brucei | phosphatidylinositol 4-kinase, putative | 0.0047 | 0.0365 | 0.4526 |
Schistosoma mansoni | tar DNA-binding protein | 0.0137 | 0.155 | 0.155 |
Brugia malayi | Heterochromatin protein 1 | 0.0072 | 0.07 | 0.2023 |
Entamoeba histolytica | hypothetical protein | 0.0277 | 0.3373 | 1 |
Mycobacterium ulcerans | beta-lactamase | 0.008 | 0.0795 | 1 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0025 | 0.0084 | 0.106 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0047 | 0.0365 | 0.4587 |
Trypanosoma brucei | phosphatidylinositol 3-kinase tor, putative | 0.0022 | 0.0044 | 0.0446 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.008 | 0.0795 | 0.0795 |
Loa Loa (eye worm) | hypothetical protein | 0.008 | 0.0795 | 0.2632 |
Schistosoma mansoni | chromobox protein | 0.0072 | 0.07 | 0.07 |
Mycobacterium tuberculosis | Conserved protein | 0.008 | 0.0795 | 0.1244 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.008 | 0.0795 | 0.0795 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.008 | 0.0795 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.008 | 0.0795 | 0.2632 |
Echinococcus granulosus | chromobox protein 1 | 0.0072 | 0.07 | 0.07 |
Brugia malayi | beta-lactamase family protein | 0.008 | 0.0795 | 0.2307 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0277 | 0.3373 | 0.3373 |
Echinococcus granulosus | tumor protein p63 | 0.0384 | 0.4772 | 0.4772 |
Mycobacterium tuberculosis | Probable lipase LipD | 0.008 | 0.0795 | 0.1244 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.