Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | glutamate receptor kainate | 0.0081 | 0.0297 | 0.093 |
Brugia malayi | Muscleblind-like protein | 0.0145 | 0.0602 | 0.2308 |
Echinococcus multilocularis | protoporphyrinogen oxidase | 0.015 | 0.0627 | 0.1907 |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.003 | 0.0061 | 0.0181 |
Schistosoma mansoni | glutamate receptor AMPA | 0.0081 | 0.0297 | 0.093 |
Schistosoma mansoni | glutamate receptor NMDA | 0.0191 | 0.0818 | 0.2624 |
Mycobacterium tuberculosis | Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) | 0.0023 | 0.0026 | 0.0009 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.006 | 0.0198 | 0.0573 |
Leishmania major | acetoin dehydrogenase e3 component-like protein | 0.0021 | 0.0018 | 0.0234 |
Leishmania major | dihydrolipoamide dehydrogenase, putative | 0.0021 | 0.0018 | 0.0234 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0095 | 0.0365 | 0.1387 |
Echinococcus multilocularis | protein patched | 0.0041 | 0.0111 | 0.03 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.0061 | 0.0193 |
Echinococcus granulosus | Glutamate receptor ionotropic kainate 2 | 0.0096 | 0.0369 | 0.109 |
Echinococcus multilocularis | Niemann Pick C1 protein | 0.0096 | 0.0369 | 0.1103 |
Schistosoma mansoni | nAChR subunit | 0.003 | 0.0061 | 0.016 |
Entamoeba histolytica | Acid sphingomyelinase-like phosphodiesterase, putative | 0.008 | 0.0296 | 0.7939 |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.003 | 0.0061 | 0.0181 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0021 | 0.0018 | 0.0234 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0041 | 0.0111 | 0.0877 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0035 | 0.0082 | 0.021 |
Echinococcus multilocularis | protein dispatched 1 | 0.0047 | 0.0138 | 0.0386 |
Entamoeba histolytica | Acid sphingomyelinase-like phosphodiesterase, putative | 0.008 | 0.0296 | 0.7939 |
Loa Loa (eye worm) | hypothetical protein | 0.015 | 0.0627 | 0.2414 |
Brugia malayi | CHE-14 protein | 0.0041 | 0.0111 | 0.0377 |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0.0136 | 0.0487 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.0061 | 0.0193 |
Toxoplasma gondii | RNA-directed DNA polymerase | 0.0177 | 0.0754 | 1 |
Schistosoma mansoni | myelin transcription factor 1 myt1 | 0.0053 | 0.0166 | 0.0503 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0023 | 0.0026 | 0.0008 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0026 | 0.0055 |
Echinococcus granulosus | suppression of tumorigenicity 18 protein | 0.0053 | 0.0166 | 0.0466 |
Brugia malayi | dihydrolipoyl dehydrogenase, mitochondrial precursor, putative | 0.0021 | 0.0018 | 0.0012 |
Wolbachia endosymbiont of Brugia malayi | 4'-phosphopantetheinyl transferase | 0.0023 | 0.0024 | 1 |
Echinococcus granulosus | muscleblind protein | 0.0145 | 0.0602 | 0.1805 |
Leishmania major | hypothetical protein, conserved | 0.0024 | 0.0032 | 0.0424 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0021 | 0.0018 | 0.0234 |
Giardia lamblia | Telomerase catalytic subunit | 0.0177 | 0.0754 | 1 |
Echinococcus multilocularis | thioredoxin glutathione reductase | 0.0062 | 0.0208 | 0.0602 |
Echinococcus multilocularis | L aminoadipate semialdehyde | 0.0081 | 0.0298 | 0.0884 |
Echinococcus multilocularis | glycine receptor subunit beta | 0.003 | 0.0061 | 0.0144 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0023 | 0.0026 | 0.0132 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0046 | 0.0135 | 0.0371 |
Echinococcus granulosus | phd:f box containing protein | 0.0024 | 0.0032 | 0.0055 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0251 | 0.1102 | 1 |
Schistosoma mansoni | acetylcholinesterase | 0.0095 | 0.0364 | 0.1146 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0084 | 0.0312 | 0.2725 |
Echinococcus granulosus | microtubule associated protein 2 | 0.067 | 0.3083 | 0.942 |
Loa Loa (eye worm) | hypothetical protein | 0.0294 | 0.1304 | 0.5069 |
Brugia malayi | Carboxylesterase family protein | 0.0095 | 0.0364 | 0.137 |
Loa Loa (eye worm) | hypothetical protein | 0.0095 | 0.0364 | 0.1381 |
Loa Loa (eye worm) | glutathione reductase | 0.0062 | 0.0208 | 0.0769 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0095 | 0.0364 | 0.1146 |
Schistosoma mansoni | nAChR subunit (ShAR1-alpha-like) | 0.003 | 0.0061 | 0.016 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0073 | 0.0242 |
Echinococcus granulosus | endonuclease exonuclease phosphatase | 0.0183 | 0.0779 | 0.2348 |
Brugia malayi | Glutamate receptor 2 precursor | 0.0081 | 0.0297 | 0.111 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0023 | 0.0026 | 0.0008 |
Mycobacterium tuberculosis | holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie | 0.0023 | 0.0024 | 0.0007 |
Echinococcus multilocularis | glutamate receptor subunit protein glur | 0.003 | 0.0058 | 0.0135 |
Loa Loa (eye worm) | carboxylesterase | 0.0095 | 0.0364 | 0.1381 |
Echinococcus granulosus | fetal alzheimer antigen falz | 0.0023 | 0.0028 | 0.0042 |
Echinococcus multilocularis | Ribosomal protein S1, RNA binding domain | 0.003 | 0.0058 | 0.0135 |
Echinococcus granulosus | lysine specific histone demethylase 1A | 0.015 | 0.0627 | 0.1881 |
Echinococcus granulosus | Ribosomal protein S1 RNA binding domain | 0.003 | 0.0058 | 0.0133 |
Brugia malayi | hypothetical protein | 0.043 | 0.1949 | 0.76 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0084 | 0.0312 | 0.2725 |
Echinococcus granulosus | glutamate receptor ionotropic kainate 3 | 0.003 | 0.0058 | 0.0133 |
Plasmodium falciparum | telomerase reverse transcriptase | 0.0177 | 0.0754 | 1 |
Schistosoma mansoni | phosphatidylserine receptor | 0.0024 | 0.0032 | 0.0067 |
Loa Loa (eye worm) | PHD-finger family protein | 0.0028 | 0.0051 | 0.0153 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0026 | 0.0055 |
Echinococcus granulosus | nicotinic acetylcholine receptor beta 1 subunit | 0.003 | 0.0061 | 0.0142 |
Brugia malayi | Neurotransmitter-gated ion-channel transmembrane region family protein | 0.003 | 0.0061 | 0.0181 |
Echinococcus granulosus | glutamate receptor subunit protein glur | 0.003 | 0.0058 | 0.0133 |
Leishmania major | tyrosyl-DNA phosphodiesterase 1 | 0.0064 | 0.022 | 0.2913 |
Schistosoma mansoni | amine oxidase | 0.015 | 0.0627 | 0.2003 |
Schistosoma mansoni | hypothetical protein | 0.004 | 0.0104 | 0.03 |
Entamoeba histolytica | Niemann-Pick C1 protein, putative | 0.0096 | 0.0369 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.0061 | 0.0193 |
Mycobacterium ulcerans | 4'-phosphopantetheinyl transferase | 0.0023 | 0.0024 | 0.0007 |
Echinococcus granulosus | glutamate receptor 2 | 0.0096 | 0.0369 | 0.109 |
Schistosoma mansoni | hypothetical protein | 0.003 | 0.0058 | 0.015 |
Mycobacterium ulcerans | carboxylesterase, LipT | 0.0095 | 0.0364 | 0.0347 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0046 | 0.0135 | 0.0402 |
Brugia malayi | PHD-finger family protein | 0.0028 | 0.0051 | 0.0141 |
Echinococcus multilocularis | sterol regulatory element binding protein | 0.0041 | 0.0111 | 0.03 |
Schistosoma mansoni | ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related | 0.0024 | 0.0032 | 0.0067 |
Echinococcus granulosus | transcription factor Dp 1 | 0.0037 | 0.0092 | 0.0239 |
Loa Loa (eye worm) | hypothetical protein | 0.0095 | 0.0364 | 0.1381 |
Echinococcus granulosus | family S9 non peptidase ue S09 family | 0.0095 | 0.0364 | 0.1072 |
Onchocerca volvulus | Telomerase reverse transcriptase homolog | 0.0649 | 0.2983 | 1 |
Echinococcus multilocularis | peregrin | 0.0031 | 0.0061 | 0.0147 |
Plasmodium falciparum | holo-[acyl-carrier-protein] synthase, putative | 0.0023 | 0.0024 | 0.0089 |
Brugia malayi | amine oxidase, flavin-containing family protein | 0.015 | 0.0627 | 0.2405 |
Onchocerca volvulus | 0.0231 | 0.1007 | 0.3317 | |
Loa Loa (eye worm) | runx1 | 0.0054 | 0.0172 | 0.0629 |
Brugia malayi | glutathione reductase | 0.0062 | 0.0208 | 0.0758 |
Onchocerca volvulus | 0.0081 | 0.0298 | 0.0922 | |
Loa Loa (eye worm) | hypothetical protein | 0.0064 | 0.0218 | 0.0811 |
Toxoplasma gondii | histone lysine methyltransferase SET/SUV39 | 0.003 | 0.0057 | 0.0531 |
Trichomonas vaginalis | set domain proteins, putative | 0.0231 | 0.1007 | 0.9124 |
Schistosoma mansoni | glutamate receptor kainate | 0.0081 | 0.0297 | 0.093 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0165 | 0.0694 | 0.6249 |
Mycobacterium leprae | PROBABLE PROTOPORPHYRINOGEN OXIDASE HEMY (PROTOPORPHYRINOGEN-IX OXIDASE) (PROTOPORPHYRINOGENASE) (PPO) | 0.015 | 0.0627 | 1 |
Onchocerca volvulus | 0.0046 | 0.0136 | 0.0372 | |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0021 | 0.0018 | 0.0234 |
Echinococcus multilocularis | jumonji domain containing protein | 0.0039 | 0.0103 | 0.0276 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0251 | 0.1102 | 1 |
Schistosoma mansoni | Cys-loop ligand gated ion channel subunit | 0.003 | 0.0061 | 0.016 |
Loa Loa (eye worm) | nicotinic acetylcholine receptor alpha subunit | 0.003 | 0.0061 | 0.0193 |
Echinococcus granulosus | Niemann Pick C1 protein | 0.0096 | 0.0369 | 0.1088 |
Echinococcus multilocularis | acetylcholinesterase | 0.056 | 0.256 | 0.7924 |
Onchocerca volvulus | 0.015 | 0.0627 | 0.2033 | |
Schistosoma mansoni | scm-relatedprotein containing 4 mbt domains (sfmbt) | 0.0046 | 0.0136 | 0.0404 |
Toxoplasma gondii | 4'-phosphopantetheinyl transferase domain-containing protein | 0.0023 | 0.0024 | 0.0089 |
Plasmodium falciparum | phd finger protein, putative | 0.0028 | 0.0051 | 0.0448 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.0061 | 0.0193 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0084 | 0.0312 | 0.2725 |
Schistosoma mansoni | hypothetical protein | 0.0035 | 0.0082 | 0.0229 |
Loa Loa (eye worm) | hypothetical protein | 0.0095 | 0.0364 | 0.1381 |
Trypanosoma brucei | trypanothione reductase | 0.0062 | 0.0208 | 0.2579 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0058 | 0.0193 | 0.0712 |
Trypanosoma brucei | phosphatidylinositol kinase related protein, putative | 0.0024 | 0.0031 | 0.0179 |
Loa Loa (eye worm) | hypothetical protein | 0.043 | 0.1949 | 0.7603 |
Brugia malayi | Glutamate receptor 1 precursor | 0.0081 | 0.0297 | 0.111 |
Brugia malayi | nicotinic acetylcholine receptor beta-1 chain precursor | 0.003 | 0.0061 | 0.0181 |
Entamoeba histolytica | hypothetical protein | 0.0035 | 0.0082 | 0.1883 |
Echinococcus multilocularis | SAM and MBT domain containing protein | 0.0046 | 0.0136 | 0.0378 |
Echinococcus multilocularis | glutamate receptor 2 | 0.0066 | 0.0229 | 0.0667 |
Trypanosoma cruzi | JmjC domain, hydroxylase, putative | 0.0024 | 0.0032 | 0.0424 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0084 | 0.0312 | 0.2725 |
Echinococcus multilocularis | glutamate receptor 2 | 0.0096 | 0.0369 | 0.1106 |
Loa Loa (eye worm) | hypothetical protein | 0.0095 | 0.0364 | 0.1381 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0023 | 0.0026 | 0.0008 |
Brugia malayi | Cation transporter family protein | 0.003 | 0.0061 | 0.0181 |
Echinococcus multilocularis | dihydrolipoamide dehydrogenase | 0.0021 | 0.0018 | 0.0011 |
Trypanosoma brucei | telomerase reverse transcriptase | 0.0177 | 0.0754 | 1 |
Echinococcus multilocularis | glutamate receptor 2 | 0.0081 | 0.0297 | 0.0881 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.003 | 0.0057 | 0.0147 |
Schistosoma mansoni | bromodomain-containing nuclear protein 1 brd1 | 0.0028 | 0.0051 | 0.0127 |
Loa Loa (eye worm) | hypothetical protein | 0.056 | 0.256 | 1 |
Schistosoma mansoni | Cys-loop ligand gated ion channel subunit | 0.003 | 0.0061 | 0.016 |
Mycobacterium ulcerans | long-chain-fatty-acid-CoA ligase | 0.0023 | 0.0026 | 0.0008 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0063 | 0.0213 | 0.1817 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.0061 | 0.0193 |
Brugia malayi | PHD-finger family protein | 0.0026 | 0.0039 | 0.0094 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.0061 | 0.0193 |
Schistosoma mansoni | niemann-pick C1 (NPC1) | 0.0097 | 0.0376 | 0.1185 |
Plasmodium vivax | hypothetical protein, conserved | 0.015 | 0.0627 | 0.827 |
Echinococcus multilocularis | suppression of tumorigenicity 18 protein | 0.0053 | 0.0166 | 0.0473 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0084 | 0.0312 | 0.2725 |
Echinococcus granulosus | carboxylesterase 5A | 0.056 | 0.256 | 0.7814 |
Echinococcus multilocularis | lysine specific demethylase 5A | 0.0091 | 0.0349 | 0.1041 |
Onchocerca volvulus | Putative nachr subunit | 0.003 | 0.0061 | 0.0118 |
Onchocerca volvulus | 0.0028 | 0.0049 | 0.0078 | |
Echinococcus granulosus | acetylcholine receptor subunit beta 1 | 0.003 | 0.0061 | 0.0142 |
Brugia malayi | gamma-aminobutyric-acid receptor beta subunit precursor | 0.003 | 0.0061 | 0.0181 |
Brugia malayi | AMP-binding enzyme family protein | 0.0023 | 0.0026 | 0.0043 |
Schistosoma mansoni | jumonji domain containing protein | 0.0131 | 0.0535 | 0.1704 |
Brugia malayi | jmjC domain containing protein | 0.0024 | 0.0032 | 0.0068 |
Schistosoma mansoni | acetyl-CoA C-acetyltransferase | 0.0023 | 0.0028 | 0.0053 |
Echinococcus multilocularis | nmda type glutamate receptor | 0.0174 | 0.0741 | 0.2261 |
Onchocerca volvulus | Polycomb protein Sfmbt homolog | 0.0046 | 0.0136 | 0.0372 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0023 | 0.0026 | 0.034 |
Echinococcus granulosus | lysine specific demethylase 6a | 0.0024 | 0.0032 | 0.0055 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.0046 | 0.0135 | 0.0376 |
Toxoplasma gondii | histone lysine demethylase JMJC1/KDM5D/JARID1D | 0.0024 | 0.0032 | 0.0195 |
Echinococcus multilocularis | neuroligin | 0.0095 | 0.0364 | 0.1087 |
Echinococcus granulosus | neuronal acetylcholine receptor subunit alpha 4 | 0.003 | 0.0061 | 0.0142 |
Loa Loa (eye worm) | acetylcholine receptor alpha subunit | 0.003 | 0.0061 | 0.0193 |
Leishmania major | trypanothione reductase | 0.0062 | 0.0208 | 0.2753 |
Brugia malayi | jmjC domain containing protein | 0.0095 | 0.0365 | 0.1376 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.0061 | 0.0193 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0111 | 0.0389 |
Echinococcus granulosus | jumonji domain containing 1A | 0.0024 | 0.0032 | 0.0055 |
Echinococcus multilocularis | Niemann Pick C1 protein | 0.0137 | 0.0563 | 0.1706 |
Schistosoma mansoni | nAChR subunit | 0.003 | 0.0061 | 0.016 |
Schistosoma mansoni | hypothetical protein | 0.0165 | 0.0694 | 0.2223 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0095 | 0.0364 | 0.0373 |
Echinococcus granulosus | glycine receptor subunit alpha 1 | 0.003 | 0.0061 | 0.0142 |
Loa Loa (eye worm) | excitatory GABA receptor EXP-1A | 0.003 | 0.0061 | 0.0193 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0095 | 0.0364 | 0.0373 |
Schistosoma mansoni | BC026374 protein (S09 family) | 0.0095 | 0.0364 | 0.1146 |
Schistosoma mansoni | neuroligin 3 (S09 family) | 0.0095 | 0.0364 | 0.1146 |
Brugia malayi | SWIRM domain containing protein | 0.015 | 0.0627 | 0.2405 |
Schistosoma mansoni | dihydrolipoamide dehydrogenase | 0.0021 | 0.0018 | 0.002 |
Echinococcus granulosus | Niemann Pick C1 protein | 0.0137 | 0.0563 | 0.1683 |
Brugia malayi | mbt repeat family protein | 0.0046 | 0.0136 | 0.0476 |
Echinococcus multilocularis | dnaJ subfamily B | 0.0397 | 0.1794 | 0.5538 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0033 | 0.0073 | 0.023 |
Echinococcus granulosus | histone acetyltransferase MYST2 | 0.0053 | 0.0166 | 0.0466 |
Schistosoma mansoni | cpg binding protein | 0.0031 | 0.0065 | 0.0174 |
Echinococcus multilocularis | Protein lozenge | 0.0054 | 0.0172 | 0.0491 |
Echinococcus granulosus | glutamate receptor NMDA | 0.0159 | 0.0668 | 0.2008 |
Brugia malayi | hypothetical protein | 0.0035 | 0.0082 | 0.0264 |
Loa Loa (eye worm) | hypothetical protein | 0.0069 | 0.0241 | 0.0902 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.015 | 0.0627 | 0.0657 |
Echinococcus multilocularis | muscleblind protein 1 | 0.0145 | 0.0602 | 0.183 |
Brugia malayi | hypothetical protein | 0.0294 | 0.1304 | 0.5063 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0251 | 0.1102 | 1 |
Toxoplasma gondii | thioredoxin reductase | 0.0062 | 0.0208 | 0.2579 |
Trichomonas vaginalis | carboxylesterase domain containing protein, putative | 0.0095 | 0.0364 | 0.3204 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.0061 | 0.0193 |
Loa Loa (eye worm) | hypothetical protein | 0.005 | 0.0154 | 0.056 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.0061 | 0.0193 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.0104 | 0.0362 |
Trypanosoma cruzi | UDP-galactopyranose mutase | 0.015 | 0.0627 | 0.8311 |
Mycobacterium ulcerans | protoporphyrinogen oxidase | 0.015 | 0.0627 | 0.061 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0084 | 0.0312 | 0.2725 |
Echinococcus granulosus | Glutamate receptor ionotropic kainate 2 | 0.0096 | 0.0369 | 0.109 |
Loa Loa (eye worm) | glutamate receptor 2 | 0.0081 | 0.0297 | 0.1121 |
Onchocerca volvulus | 0.003 | 0.0061 | 0.0118 | |
Loa Loa (eye worm) | abnormal chemotaxis protein 14 | 0.0041 | 0.0111 | 0.0389 |
Schistosoma mansoni | patched 1 | 0.0041 | 0.0111 | 0.0323 |
Trichomonas vaginalis | glutathione reductase, putative | 0.0021 | 0.0018 | 0.002 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0021 | 0.0018 | 0.0234 |
Echinococcus granulosus | dnaJ subfamily B | 0.0397 | 0.1794 | 0.5462 |
Echinococcus multilocularis | expressed conserved protein | 0.009 | 0.0341 | 0.1018 |
Onchocerca volvulus | 0.003 | 0.0061 | 0.0118 | |
Echinococcus granulosus | nAChR subunit | 0.003 | 0.0061 | 0.0142 |
Schistosoma mansoni | glutamate receptor kainate | 0.0081 | 0.0297 | 0.093 |
Toxoplasma gondii | PHD-finger domain-containing protein | 0.0028 | 0.0051 | 0.0448 |
Schistosoma mansoni | bromodomain containing protein | 0.0063 | 0.0215 | 0.0662 |
Schistosoma mansoni | nAChR subunit (ShAR1-beta-like) | 0.003 | 0.0061 | 0.016 |
Toxoplasma gondii | histone lysine-specific demethylase | 0.015 | 0.0627 | 0.827 |
Echinococcus multilocularis | serine protein kinase ATM | 0.0024 | 0.0031 | 0.0052 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0035 | 0.0082 | 0.0211 |
Echinococcus multilocularis | glycine receptor subunit alpha 1 | 0.003 | 0.0061 | 0.0144 |
Schistosoma mansoni | glutamate receptor NMDA | 0.0255 | 0.1121 | 0.3612 |
Schistosoma mansoni | nAChR subunit | 0.003 | 0.0061 | 0.016 |
Echinococcus granulosus | Glutamate receptor ionotropic kainate 2 | 0.0096 | 0.0369 | 0.109 |
Echinococcus granulosus | tyrosyl DNA phosphodiesterase 1 | 0.0064 | 0.022 | 0.0631 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0251 | 0.1102 | 1 |
Brugia malayi | Carboxylesterase family protein | 0.0095 | 0.0364 | 0.137 |
Schistosoma mansoni | hypothetical protein | 0.0028 | 0.0051 | 0.0127 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.0061 | 0.0193 |
Plasmodium falciparum | thioredoxin reductase | 0.0062 | 0.0208 | 0.2579 |
Echinococcus granulosus | lysine specific demethylase 5A | 0.0095 | 0.0365 | 0.1076 |
Giardia lamblia | PHD finger protein 15 | 0.0028 | 0.0051 | 0.0448 |
Echinococcus multilocularis | glutamate receptor ionotropic kainate | 0.003 | 0.0058 | 0.0135 |
Entamoeba histolytica | hypothetical protein | 0.0024 | 0.0031 | 0.0435 |
Echinococcus multilocularis | Glutamate receptor, ionotropic kainate 2 | 0.0096 | 0.0369 | 0.1106 |
Onchocerca volvulus | 0.0095 | 0.0364 | 0.1142 | |
Brugia malayi | jmjC domain containing protein | 0.0024 | 0.0032 | 0.0068 |
Echinococcus multilocularis | glutamate (NMDA) receptor subunit | 0.0191 | 0.0818 | 0.25 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.0061 | 0.0193 |
Brugia malayi | C2-HC type zinc finger protein C.e-MyT1 | 0.0053 | 0.0166 | 0.0595 |
Schistosoma mansoni | hypothetical protein | 0.0397 | 0.1794 | 0.5802 |
Onchocerca volvulus | 0.003 | 0.0061 | 0.0118 | |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.0061 | 0.0193 |
Entamoeba histolytica | hypothetical protein | 0.0023 | 0.0024 | 0.0246 |
Echinococcus multilocularis | conserved hypothetical protein | 0.0701 | 0.3227 | 1 |
Schistosoma mansoni | phd/f-box containing protein | 0.0024 | 0.0032 | 0.0067 |
Echinococcus multilocularis | acetylcholinesterase | 0.056 | 0.256 | 0.7924 |
Echinococcus multilocularis | neuronal acetylcholine receptor subunit alpha 4 | 0.003 | 0.0061 | 0.0144 |
Trypanosoma cruzi | telomerase reverse transcriptase, putative | 0.0177 | 0.0754 | 1 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0024 | 0.0031 | 0.0142 |
Echinococcus multilocularis | glycine receptor subunit alpha 1 | 0.003 | 0.0061 | 0.0144 |
Trypanosoma cruzi | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.0064 | 0.022 | 0.2913 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0015 | 0.0013 |
Schistosoma mansoni | hypothetical protein | 0.0033 | 0.0073 | 0.0201 |
Brugia malayi | nicotinic acetylcholine receptor alpha subunit, putative | 0.003 | 0.0061 | 0.0181 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0021 | 0.0018 | 0.0234 |
Echinococcus granulosus | nmda type glutamate receptor | 0.0189 | 0.0809 | 0.244 |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.003 | 0.0061 | 0.0181 |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.0056 | 0.0182 | 0.2237 |
Echinococcus granulosus | para nitrobenzyl esterase | 0.0095 | 0.0364 | 0.1072 |
Schistosoma mansoni | protein phosphatase 2C | 0.0024 | 0.0032 | 0.0067 |
Plasmodium vivax | JmjC domain containing protein | 0.0024 | 0.0032 | 0.0195 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0024 | 0.0032 | 0.008 |
Plasmodium vivax | holo-[acyl-carrier-protein] synthase, putative | 0.0023 | 0.0024 | 0.0089 |
Loa Loa (eye worm) | hypothetical protein | 0.0095 | 0.0364 | 0.1381 |
Onchocerca volvulus | 0.003 | 0.0057 | 0.0105 | |
Trichomonas vaginalis | mercuric reductase, putative | 0.0021 | 0.0018 | 0.002 |
Mycobacterium tuberculosis | Carboxylesterase LipT | 0.0095 | 0.0364 | 0.0373 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.003 | 0.0057 | 0.0147 |
Loa Loa (eye worm) | tyrosyl-DNA phosphodiesterase | 0.0064 | 0.022 | 0.0817 |
Brugia malayi | Niemann-Pick C1 protein precursor | 0.0096 | 0.0369 | 0.1391 |
Entamoeba histolytica | hypothetical protein | 0.0035 | 0.0082 | 0.1883 |
Toxoplasma gondii | 4'-phosphopantetheinyl transferase superfamily protein | 0.0023 | 0.0024 | 0.0089 |
Echinococcus multilocularis | nicotinic acetylcholine receptor alpha subunit | 0.003 | 0.0061 | 0.0144 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0051 | 0.0153 |
Loa Loa (eye worm) | carboxylesterase | 0.056 | 0.256 | 1 |
Echinococcus multilocularis | jumonji domain containing 1A | 0.0024 | 0.0032 | 0.0055 |
Echinococcus multilocularis | PHD finger protein rhinoceros | 0.0028 | 0.0051 | 0.0113 |
Leishmania major | telomerase reverse transcriptase, putative | 0.0177 | 0.0754 | 1 |
Brugia malayi | AMP-binding enzyme family protein | 0.0023 | 0.0026 | 0.0043 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.0028 | 0.0049 | 0.0146 |
Loa Loa (eye worm) | O-glycosyl hydrolase family 30 protein | 0.0251 | 0.1102 | 0.4278 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.0061 | 0.0193 |
Echinococcus granulosus | cpg binding protein | 0.0031 | 0.0065 | 0.0156 |
Echinococcus granulosus | JmjC domain containing protein 4 | 0.0024 | 0.0032 | 0.0055 |
Echinococcus multilocularis | polycomb protein SCMH1 | 0.0046 | 0.0136 | 0.0378 |
Echinococcus multilocularis | nicotinic acetylcholine receptor a11 subunit | 0.003 | 0.0061 | 0.0144 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0035 | 0.0082 | 0.0207 |
Plasmodium falciparum | protoporphyrinogen oxidase | 0.015 | 0.0627 | 0.827 |
Mycobacterium ulcerans | hypothetical protein | 0.0023 | 0.0026 | 0.0008 |
Schistosoma mansoni | cpg binding protein | 0.0028 | 0.0049 | 0.0121 |
Echinococcus multilocularis | phd:f box containing protein | 0.0024 | 0.0032 | 0.0055 |
Echinococcus granulosus | sterol regulatory element binding protein | 0.0041 | 0.0111 | 0.0296 |
Brugia malayi | O-Glycosyl hydrolase family 30 protein | 0.0251 | 0.1102 | 0.4271 |
Onchocerca volvulus | 0.0095 | 0.0364 | 0.1142 | |
Echinococcus granulosus | dihydrolipoamide dehydrogenase | 0.0021 | 0.0018 | 0.0011 |
Schistosoma mansoni | ATP-binding cassette transporter | 0.0081 | 0.0297 | 0.093 |
Trypanosoma cruzi | telomerase reverse transcriptase, putative | 0.0177 | 0.0754 | 1 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0023 | 0.0024 | 0.0089 |
Trypanosoma cruzi | dihydrolipoyl dehydrogenase, putative | 0.0021 | 0.0018 | 0.0234 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0084 | 0.0312 | 0.2725 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.0061 | 0.0193 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.0061 | 0.0193 |
Brugia malayi | Tyrosyl-DNA phosphodiesterase family protein | 0.0064 | 0.022 | 0.0806 |
Echinococcus multilocularis | Glutamate receptor, ionotropic kainate 2 | 0.0096 | 0.0369 | 0.1106 |
Echinococcus granulosus | Transcription factor JmjC domain containing protein | 0.015 | 0.0625 | 0.1874 |
Echinococcus granulosus | expressed conserved protein | 0.009 | 0.0341 | 0.1004 |
Plasmodium falciparum | JmjC domain-containing protein, putative | 0.0024 | 0.0032 | 0.0195 |
Loa Loa (eye worm) | nicotinic acetylcholine receptor non-alpha subunit | 0.003 | 0.0061 | 0.0193 |
Brugia malayi | Neurotransmitter-gated ion-channel transmembrane region family protein | 0.003 | 0.0061 | 0.0181 |
Schistosoma mansoni | sex comb on midleg homolog | 0.0046 | 0.0136 | 0.0404 |
Echinococcus multilocularis | JmjC domain containing protein 4 | 0.0024 | 0.0032 | 0.0055 |
Schistosoma mansoni | Lysine-specific histone demethylase 1 | 0.015 | 0.0627 | 0.2003 |
Toxoplasma gondii | histone lysine demethylase JMJD6a | 0.0024 | 0.0032 | 0.0195 |
Onchocerca volvulus | Glucosylceramidase homolog | 0.0165 | 0.0694 | 0.2261 |
Entamoeba histolytica | hypothetical protein | 0.0035 | 0.0082 | 0.1883 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0165 | 0.0694 | 0.6249 |
Entamoeba histolytica | tyrosyl-DNA phosphodiesterase, putative | 0.0064 | 0.022 | 0.5785 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0095 | 0.0365 | 0.115 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.003 | 0.0057 | 0.0132 |
Echinococcus granulosus | lysine specific histone demethylase 1A | 0.015 | 0.0627 | 0.1881 |
Echinococcus multilocularis | lysine specific demethylase 6a | 0.0024 | 0.0032 | 0.0055 |
Loa Loa (eye worm) | hypothetical protein | 0.0095 | 0.0364 | 0.1381 |
Loa Loa (eye worm) | hypothetical protein | 0.056 | 0.256 | 1 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0251 | 0.1102 | 1 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0023 | 0.0026 | 0.0132 |
Brugia malayi | Cation transporter family protein | 0.003 | 0.0061 | 0.0181 |
Echinococcus multilocularis | glutamate receptor, ionotrophic, AMPA 3 | 0.0096 | 0.0369 | 0.1106 |
Echinococcus granulosus | nicotinic acetylcholine receptor subunit type | 0.003 | 0.0061 | 0.0142 |
Loa Loa (eye worm) | LGC-31 protein | 0.003 | 0.0061 | 0.0193 |
Echinococcus multilocularis | cpg binding protein | 0.0031 | 0.0065 | 0.0158 |
Giardia lamblia | NADPH oxidoreductase, putative | 0.0084 | 0.0312 | 0.3989 |
Echinococcus multilocularis | carboxylesterase 5A | 0.056 | 0.256 | 0.7924 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0023 | 0.0026 | 0.0009 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.056 | 0.256 | 0.8297 |
Schistosoma mansoni | jumonji domain containing protein | 0.0024 | 0.0032 | 0.0067 |
Echinococcus multilocularis | glycine receptor subunit alpha 1 | 0.003 | 0.0061 | 0.0144 |
Chlamydia trachomatis | holo [acyl-carrier protein] synthase | 0.0023 | 0.0024 | 0.0107 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0023 | 0.0026 | 0.0008 |
Plasmodium vivax | glutathione reductase, putative | 0.0062 | 0.0208 | 0.2579 |
Mycobacterium tuberculosis | NADPH-dependent mycothiol reductase Mtr | 0.0062 | 0.0208 | 0.0205 |
Trypanosoma brucei | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.0064 | 0.022 | 0.2744 |
Loa Loa (eye worm) | hypothetical protein | 0.015 | 0.0627 | 0.2414 |
Brugia malayi | Cation transporter family protein | 0.003 | 0.0061 | 0.0181 |
Echinococcus granulosus | polycomb protein SCMH1 | 0.0046 | 0.0136 | 0.0373 |
Echinococcus granulosus | peregrin | 0.0031 | 0.0061 | 0.0145 |
Echinococcus granulosus | jumonji domain containing protein | 0.0039 | 0.0103 | 0.0273 |
Brugia malayi | Bromodomain containing protein | 0.0074 | 0.0269 | 0.0997 |
Brugia malayi | hypothetical protein | 0.0095 | 0.0364 | 0.137 |
Echinococcus multilocularis | endonuclease exonuclease phosphatase | 0.0183 | 0.0779 | 0.2381 |
Loa Loa (eye worm) | ACC-1 protein | 0.003 | 0.0061 | 0.0193 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0165 | 0.0694 | 0.6249 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0048 | 0.0146 | 0.0526 |
Brugia malayi | jmjC domain containing protein | 0.0024 | 0.0032 | 0.0068 |
Toxoplasma gondii | FATC domain-containing protein | 0.0024 | 0.0031 | 0.0179 |
Echinococcus multilocularis | muscleblind protein | 0.0145 | 0.0602 | 0.183 |
Plasmodium vivax | protoporphyrinogen oxidase, putative | 0.015 | 0.0627 | 0.827 |
Echinococcus multilocularis | histone acetyltransferase MYST2 | 0.0053 | 0.0166 | 0.0473 |
Echinococcus granulosus | glutamate receptor ionotropic kainate | 0.003 | 0.0058 | 0.0133 |
Trypanosoma cruzi | UDP-galactopyranose mutase | 0.015 | 0.0627 | 0.8311 |
Schistosoma mansoni | glutamate receptor AMPA | 0.0081 | 0.0297 | 0.093 |
Schistosoma mansoni | zinc finger protein | 0.0021 | 0.0014 | 0.0009 |
Echinococcus multilocularis | lysine specific histone demethylase 1A | 0.015 | 0.0627 | 0.1907 |
Mycobacterium ulcerans | phosphopantetheinyl transferase, PptII | 0.0023 | 0.0024 | 0.0007 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0084 | 0.0312 | 0.2725 |
Brugia malayi | jmjC domain containing protein | 0.015 | 0.0625 | 0.2397 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0095 | 0.0364 | 0.1146 |
Loa Loa (eye worm) | MBCTL1 | 0.0053 | 0.0166 | 0.0606 |
Echinococcus granulosus | SAM and MBT domain containing protein | 0.0046 | 0.0136 | 0.0373 |
Echinococcus granulosus | glycine receptor subunit beta | 0.003 | 0.0061 | 0.0142 |
Loa Loa (eye worm) | ACC-1 protein | 0.003 | 0.0061 | 0.0193 |
Giardia lamblia | NADPH oxidoreductase, putative | 0.0084 | 0.0312 | 0.3989 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0023 | 0.0026 | 0.0288 |
Brugia malayi | Carboxylesterase family protein | 0.056 | 0.256 | 1 |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.003 | 0.0061 | 0.0181 |
Brugia malayi | excitatory GABA receptor EXP-1A | 0.003 | 0.0061 | 0.0181 |
Schistosoma mansoni | nAChR subunit | 0.003 | 0.0061 | 0.016 |
Echinococcus multilocularis | geminin | 0.0165 | 0.0694 | 0.2117 |
Mycobacterium leprae | conserved hypothetical protein | 0.0023 | 0.0024 | 0.0107 |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0.0135 | 0.0484 |
Echinococcus multilocularis | acetylcholine receptor subunit beta 1 | 0.003 | 0.0061 | 0.0144 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0165 | 0.0694 | 0.6249 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0084 | 0.0312 | 0.2725 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0024 | 0.0032 | 0.008 |
Plasmodium falciparum | lysine-specific histone demethylase 1, putative | 0.015 | 0.0627 | 0.827 |
Brugia malayi | Serotonin receptor | 0.0477 | 0.2169 | 0.8463 |
Brugia malayi | mbt repeat family protein | 0.0046 | 0.0136 | 0.0476 |
Trypanosoma cruzi | phosphatidylinositol kinase related protein, putative | 0.0021 | 0.0015 | 0.0197 |
Brugia malayi | acetylcholine receptor, alpha-type subunit unc-38 precursor | 0.003 | 0.0061 | 0.0181 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0024 | 0.0032 | 0.008 |
Schistosoma mansoni | aminoadipate-semialdehyde dehydrogenase | 0.0081 | 0.0298 | 0.0934 |
Echinococcus multilocularis | nicotinic acetylcholine receptor beta 1 subunit | 0.003 | 0.0061 | 0.0144 |
Brugia malayi | Phosphatidylinositol 3- and 4-kinase family protein | 0.0024 | 0.0031 | 0.0064 |
Onchocerca volvulus | 0.003 | 0.0061 | 0.0118 | |
Echinococcus multilocularis | fetal alzheimer antigen, falz | 0.0023 | 0.0028 | 0.0042 |
Brugia malayi | Bromodomain containing protein | 0.0031 | 0.0061 | 0.0184 |
Mycobacterium ulcerans | long-chain-fatty-acid--CoA ligase | 0.0023 | 0.0026 | 0.0008 |
Echinococcus multilocularis | glutamate receptor NMDA | 0.0159 | 0.0668 | 0.2036 |
Schistosoma mansoni | cpg binding protein | 0.0031 | 0.0065 | 0.0174 |
Schistosoma mansoni | nAChR subunit (ShAR1-beta2-like) | 0.003 | 0.0061 | 0.016 |
Echinococcus granulosus | acetylcholinesterase | 0.056 | 0.256 | 0.7814 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0021 | 0.0018 | 0.0234 |
Plasmodium vivax | SET domain protein, putative | 0.003 | 0.0057 | 0.0531 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0173 | 0.0736 | 0.6635 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0203 | 0.0875 | 0.3387 |
Echinococcus multilocularis | Jumonji, AT rich interactive domain 1B | 0.0028 | 0.0048 | 0.0106 |
Schistosoma mansoni | amine oxidase | 0.015 | 0.0627 | 0.2003 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0084 | 0.0312 | 0.2725 |
Mycobacterium tuberculosis | Probable flavin-containing monoamine oxidase AofH (amine oxidase) (MAO) | 0.1984 | 0.929 | 1 |
Echinococcus granulosus | glycine receptor subunit beta | 0.003 | 0.0061 | 0.0142 |
Echinococcus granulosus | nicotinic acetylcholine receptor subunit alpha 8 | 0.003 | 0.0061 | 0.0142 |
Treponema pallidum | 4'-phosphopantetheinyl transferase | 0.0023 | 0.0024 | 1 |
Onchocerca volvulus | 0.003 | 0.0061 | 0.0118 | |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.0032 | 0.008 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.0061 | 0.0193 |
Echinococcus multilocularis | NMDA receptor | 0.003 | 0.0058 | 0.0135 |
Trypanosoma cruzi | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.0064 | 0.022 | 0.2913 |
Schistosoma mansoni | hypothetical protein | 0.004 | 0.0104 | 0.03 |
Trypanosoma cruzi | dihydrolipoyl dehydrogenase, putative | 0.0021 | 0.0018 | 0.0234 |
Brugia malayi | acetylcholine receptor protein, alpha-like chain, putative | 0.003 | 0.0061 | 0.0181 |
Plasmodium falciparum | conserved Plasmodium protein, unknown function | 0.015 | 0.0627 | 0.827 |
Giardia lamblia | NADPH oxidoreductase, putative | 0.0084 | 0.0312 | 0.3989 |
Mycobacterium ulcerans | flavin-containing monoamine oxidase AofH | 0.2134 | 1 | 1 |
Echinococcus multilocularis | tyrosyl DNA phosphodiesterase 1 | 0.0064 | 0.022 | 0.064 |
Mycobacterium ulcerans | long-chain fatty-acid CoA ligase | 0.0023 | 0.0026 | 0.0008 |
Echinococcus multilocularis | transcription factor Dp 1 | 0.0037 | 0.0092 | 0.0243 |
Schistosoma mansoni | tyrosyl-DNA phosphodiesterase | 0.0064 | 0.022 | 0.0678 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0046 | 0.0135 | 0.0402 |
Loa Loa (eye worm) | hypothetical protein | 0.0096 | 0.0369 | 0.1401 |
Loa Loa (eye worm) | hypothetical protein | 0.0048 | 0.0146 | 0.0526 |
Brugia malayi | Carboxylesterase family protein | 0.0095 | 0.0364 | 0.137 |
Echinococcus granulosus | Protein patched homolog 1 | 0.0041 | 0.0111 | 0.0296 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0035 | 0.0082 | 0.0229 |
Echinococcus granulosus | glutamate receptor 2 | 0.0066 | 0.0229 | 0.0658 |
Loa Loa (eye worm) | mbt repeat family protein | 0.0046 | 0.0136 | 0.0487 |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.0028 | 0.0049 | 0.0106 |
Echinococcus granulosus | glycine receptor subunit alpha 1 | 0.003 | 0.0061 | 0.0142 |
Onchocerca volvulus | 0.0294 | 0.1304 | 0.4321 | |
Chlamydia trachomatis | protoporphyrinogen oxidase | 0.015 | 0.0627 | 1 |
Plasmodium vivax | hypothetical protein, conserved | 0.015 | 0.0627 | 0.827 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0165 | 0.0694 | 0.6249 |
Echinococcus multilocularis | nicotinic acetylcholine receptor subunit alpha 8 | 0.003 | 0.0061 | 0.0144 |
Loa Loa (eye worm) | glutamate-gated chloride channel alpha3A subunit | 0.003 | 0.0061 | 0.0193 |
Echinococcus multilocularis | Glutamate receptor, ionotropic kainate 2 | 0.0096 | 0.0369 | 0.1106 |
Echinococcus granulosus | glycine receptor subunit alpha 1 | 0.003 | 0.0061 | 0.0142 |
Leishmania major | 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein | 0.0021 | 0.0018 | 0.0234 |
Leishmania major | UDP-galactopyranose mutase | 0.015 | 0.0627 | 0.8311 |
Echinococcus multilocularis | family S9 non peptidase ue (S09 family) | 0.0095 | 0.0364 | 0.1087 |
Brugia malayi | CXXC zinc finger family protein | 0.0028 | 0.0049 | 0.0134 |
Schistosoma mansoni | hypothetical protein | 0.0282 | 0.1247 | 0.4023 |
Leishmania major | phosphopantetheinyl transferase-like protein | 0.0023 | 0.0024 | 0.032 |
Mycobacterium tuberculosis | Possible oxidoreductase | 0.015 | 0.0627 | 0.0657 |
Echinococcus multilocularis | nAChR subunit | 0.003 | 0.0061 | 0.0144 |
Plasmodium falciparum | glutathione reductase | 0.0062 | 0.0208 | 0.2579 |
Loa Loa (eye worm) | hypothetical protein | 0.043 | 0.1949 | 0.7603 |
Echinococcus granulosus | Jumonji AT rich interactive domain 1B | 0.0028 | 0.0048 | 0.0105 |
Onchocerca volvulus | Alhambra homolog | 0.0028 | 0.0051 | 0.0084 |
Onchocerca volvulus | 0.0095 | 0.0364 | 0.1142 | |
Brugia malayi | Thioredoxin reductase | 0.0062 | 0.0208 | 0.0758 |
Loa Loa (eye worm) | hypothetical protein | 0.0081 | 0.0298 | 0.1125 |
Echinococcus multilocularis | BC026374 protein (S09 family) | 0.0095 | 0.0364 | 0.1087 |
Echinococcus granulosus | hypothetical protein | 0.071 | 0.3273 | 1 |
Brugia malayi | Bromodomain containing protein | 0.0037 | 0.0093 | 0.0306 |
Trypanosoma cruzi | phosphatidylinositol kinase related protein, putative | 0.0024 | 0.0031 | 0.0409 |
Brugia malayi | jmjC domain containing protein | 0.0024 | 0.0032 | 0.0068 |
Schistosoma mansoni | gliotactin | 0.0095 | 0.0364 | 0.1146 |
Echinococcus granulosus | PHD finger protein rhinoceros | 0.0028 | 0.0051 | 0.0112 |
Brugia malayi | hypothetical protein | 0.015 | 0.0627 | 0.2405 |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.003 | 0.0061 | 0.0181 |
Onchocerca volvulus | 0.003 | 0.0061 | 0.0118 | |
Entamoeba histolytica | acyl-coA synthetase, putative | 0.0023 | 0.0026 | 0.0288 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0048 | 0.0146 | 0.0514 |
Echinococcus multilocularis | para nitrobenzyl esterase | 0.0095 | 0.0364 | 0.1087 |
Loa Loa (eye worm) | hypothetical protein | 0.015 | 0.0627 | 0.2414 |
Toxoplasma gondii | histone lysine-specific demethylase LSD1/BHC110/KDMA1A | 0.0152 | 0.0635 | 0.838 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.006 | 0.0198 | 0.0565 |
Plasmodium vivax | telomerase reverse transcriptase, putative | 0.0177 | 0.0754 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0145 | 0.0602 | 0.2318 |
Brugia malayi | Neurotransmitter-gated ion-channel transmembrane region family protein | 0.003 | 0.0061 | 0.0181 |
Echinococcus granulosus | L aminoadipate semialdehyde | 0.0081 | 0.0298 | 0.0872 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0023 | 0.0026 | 0.034 |
Schistosoma mansoni | nAChR subunit | 0.003 | 0.0061 | 0.016 |
Echinococcus granulosus | neuroligin | 0.0095 | 0.0364 | 0.1072 |
Echinococcus granulosus | Cys loop ligand gated ion channel subunit | 0.003 | 0.0061 | 0.0142 |
Mycobacterium ulcerans | dehydrogenase | 0.015 | 0.0627 | 0.061 |
Echinococcus multilocularis | nmda type glutamate receptor | 0.0189 | 0.0809 | 0.2474 |
Onchocerca volvulus | 0.0095 | 0.0364 | 0.1142 | |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0165 | 0.0694 | 0.6249 |
Echinococcus multilocularis | microtubule associated protein 2 | 0.067 | 0.3083 | 0.9552 |
Onchocerca volvulus | 0.0095 | 0.0364 | 0.1142 | |
Echinococcus granulosus | acetylcholinesterase | 0.056 | 0.256 | 0.7814 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.056 | 0.256 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.0061 | 0.0193 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0165 | 0.0694 | 0.6249 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0095 | 0.0365 | 0.115 |
Toxoplasma gondii | PHD-finger domain-containing protein | 0.0028 | 0.0051 | 0.0448 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.0032 | 0.008 |
Loa Loa (eye worm) | carboxylesterase | 0.0095 | 0.0364 | 0.1381 |
Brugia malayi | Telomerase reverse transcriptase | 0.0472 | 0.2146 | 0.837 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0084 | 0.0312 | 0.2725 |
Loa Loa (eye worm) | hypothetical protein | 0.015 | 0.0627 | 0.2414 |
Echinococcus granulosus | BC026374 protein S09 family | 0.0095 | 0.0364 | 0.1072 |
Loa Loa (eye worm) | glutamate receptor 1 | 0.0081 | 0.0297 | 0.1121 |
Brugia malayi | Hypothetical glycine receptor like protein T20B12.9 in chromosome III | 0.003 | 0.0061 | 0.0181 |
Trypanosoma cruzi | JmjC domain, hydroxylase, putative | 0.0024 | 0.0032 | 0.0424 |
Schistosoma mansoni | sex comb on midleg homolog | 0.0046 | 0.0136 | 0.0404 |
Echinococcus granulosus | serine protein kinase ATM | 0.0024 | 0.0031 | 0.0051 |
Mycobacterium ulcerans | monoamine oxidase | 0.015 | 0.0627 | 0.061 |
Trypanosoma brucei | JmjC domain, hydroxylase, putative | 0.0024 | 0.0032 | 0.0195 |
Echinococcus granulosus | nmda type glutamate receptor | 0.0174 | 0.0741 | 0.223 |
Schistosoma mansoni | hypothetical protein | 0.004 | 0.0104 | 0.03 |
Loa Loa (eye worm) | hypothetical protein | 0.0053 | 0.0166 | 0.0606 |
Schistosoma mansoni | hypothetical protein | 0.0165 | 0.0694 | 0.2223 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0023 | 0.0026 | 0.034 |
Echinococcus multilocularis | Cys loop ligand gated ion channel subunit | 0.003 | 0.0061 | 0.0144 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0021 | 0.0018 | 0.0234 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0062 | 0.0208 | 0.2753 |
Echinococcus granulosus | nicotinic acetylcholine receptor alpha subunit | 0.003 | 0.0061 | 0.0142 |
Schistosoma mansoni | ataxia telangiectasia mutated (atm) | 0.0024 | 0.0031 | 0.0063 |
Schistosoma mansoni | hypothetical protein | 0.004 | 0.0104 | 0.03 |
Echinococcus multilocularis | Glutamate receptor, ionotropic kainate 3 | 0.003 | 0.0058 | 0.0135 |
Loa Loa (eye worm) | hypothetical protein | 0.0145 | 0.0602 | 0.2318 |
Brugia malayi | Pre-SET motif family protein | 0.003 | 0.0057 | 0.0165 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0093 | 0.0319 |
Plasmodium vivax | lysine-specific histone demethylase 1, putative | 0.015 | 0.0627 | 0.827 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.012 | 0.0426 |
Loa Loa (eye worm) | hypothetical protein | 0.008 | 0.0296 | 0.1115 |
Trichomonas vaginalis | NAD(P)H dehydrogenase, putative | 0.0084 | 0.0312 | 0.2725 |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.003 | 0.0061 | 0.0181 |
Echinococcus granulosus | nicotinic acetylcholine receptor a11 subunit | 0.003 | 0.0061 | 0.0142 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0173 | 0.0736 | 0.6635 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0251 | 0.1102 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.0061 | 0.0193 |
Loa Loa (eye worm) | thioredoxin reductase | 0.0062 | 0.0208 | 0.0769 |
Mycobacterium ulcerans | oxidoreductase | 0.015 | 0.0627 | 0.061 |
Schistosoma mansoni | Protoporphyrinogen oxidase chloroplast/mitochondrial precursor | 0.015 | 0.0627 | 0.2003 |
Echinococcus granulosus | thioredoxin glutathione reductase | 0.0062 | 0.0208 | 0.0594 |
Echinococcus granulosus | geminin | 0.0165 | 0.0694 | 0.2088 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0026 | 0.0055 |
Brugia malayi | Carboxylesterase family protein | 0.0095 | 0.0364 | 0.137 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0023 | 0.0026 | 0.0288 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0084 | 0.0312 | 0.2725 |
Echinococcus multilocularis | glycine receptor subunit beta | 0.003 | 0.0061 | 0.0144 |
Loa Loa (eye worm) | hypothetical protein | 0.0095 | 0.0364 | 0.1381 |
Brugia malayi | AMP-binding enzyme family protein | 0.0023 | 0.0026 | 0.0043 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0035 | 0.0082 | 0.0208 |
Echinococcus multilocularis | 0.015 | 0.0627 | 0.1907 | |
Loa Loa (eye worm) | ligand-Gated ion Channel family member | 0.003 | 0.0061 | 0.0193 |
Trichomonas vaginalis | NAD(P)H dehydrogenase, putative | 0.0084 | 0.0312 | 0.2725 |
Brugia malayi | Pre-SET motif family protein | 0.0203 | 0.0875 | 0.3379 |
Echinococcus multilocularis | Transcription factor, JmjC domain containing protein | 0.015 | 0.0625 | 0.1901 |
Plasmodium vivax | thioredoxin reductase, putative | 0.0062 | 0.0208 | 0.2579 |
Leishmania major | dihydrolipoamide dehydrogenase, putative | 0.0021 | 0.0018 | 0.0234 |
Brugia malayi | aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase | 0.0081 | 0.0298 | 0.1115 |
Onchocerca volvulus | 0.043 | 0.1949 | 0.6505 | |
Entamoeba histolytica | hypothetical protein | 0.0035 | 0.0082 | 0.1883 |
Schistosoma mansoni | Cys-loop ligand gated ion channel subunit | 0.003 | 0.0061 | 0.016 |
Schistosoma mansoni | lozenge | 0.0054 | 0.0172 | 0.0522 |
Brugia malayi | acetylcholine receptor alpha subunit precursor, putative | 0.003 | 0.0061 | 0.0181 |
Loa Loa (eye worm) | hypothetical protein | 0.015 | 0.0627 | 0.2414 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0084 | 0.0312 | 0.2725 |
Echinococcus granulosus | glutamate receptor ionotrophic AMPA 3 | 0.0096 | 0.0369 | 0.109 |
Schistosoma mansoni | nAChR subunit | 0.003 | 0.0061 | 0.016 |
Brugia malayi | Carboxylesterase family protein | 0.056 | 0.256 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.015 | 0.0627 | 0.2414 |
Plasmodium vivax | hypothetical protein, conserved | 0.0028 | 0.0051 | 0.0448 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.0061 | 0.0193 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0048 | 0.0146 | 0.0514 |
Trichomonas vaginalis | spcc417.12 protein, putative | 0.0095 | 0.0364 | 0.3204 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0095 | 0.0364 | 0.1146 |
Echinococcus granulosus | glutamate NMDA receptor subunit | 0.0191 | 0.0818 | 0.2466 |
Trichomonas vaginalis | NAD(P)H dehydrogenase, putative | 0.0084 | 0.0312 | 0.2725 |
Schistosoma mansoni | microtubule-associated protein tau | 0.067 | 0.3083 | 1 |
Schistosoma mansoni | nAChR subunit | 0.003 | 0.0061 | 0.016 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.006 | 0.0201 | 0.0618 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Distribution coefficient | = 4.92 | Distribution coefficient was measured at an aqueous phase buffered at pH 7.4 and octanol | ChEMBL. | 2342069 |
Distribution coefficient | = 24.6 | Distribution coefficient and iron(III) complex was measured at an aqueous phase buffered at pH 7.4 and octanol | ChEMBL. | 2342069 |
mean log D (ADMET) | = 0.69 | Compound was tested for their chelating potential (free ligand) determined by distribution coefficient method. | ChEMBL. | 8809155 |
mean log D (ADMET) | = 1.25 | Compound was tested for their chelating potential with gallium-III complex determined by distribution coefficient method. | ChEMBL. | 8809155 |
mean log D (ADMET) | = 1.49 | Compound was tested for their chelating potential with Iron-III complex determined by distribution coefficient method. | ChEMBL. | 8809155 |
mean log D (ADMET) | = 2.11 | Compound was tested for their chelating potential with Indium-III complex determined by distribution coefficient method. | ChEMBL. | 8809155 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
2 literature references were collected for this gene.