Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | thioredoxin reductase | 0.0052 | 0.0425 | 0.1556 |
Loa Loa (eye worm) | hypothetical protein | 0.0096 | 0.0988 | 0.3614 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0067 | 0.0616 | 0.2255 |
Wolbachia endosymbiont of Brugia malayi | exonuclease III | 0.002 | 0 | 0.5 |
Echinococcus multilocularis | microtubule associated protein 2 | 0.0726 | 0.9188 | 0.9188 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0041 | 0.027 | 0.0294 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0049 | 0.0379 | 0.0413 |
Echinococcus multilocularis | Niemann Pick C1 protein | 0.0137 | 0.1522 | 0.1522 |
Brugia malayi | nuclear hormone receptor | 0.0041 | 0.027 | 0.0989 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0041 | 0.027 | 0.027 |
Schistosoma mansoni | patched 1 | 0.0041 | 0.0277 | 0.0301 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0071 | 0.0661 | 0.0719 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0041 | 0.027 | 0.0989 |
Entamoeba histolytica | hypothetical protein | 0.0071 | 0.0661 | 0.6686 |
Brugia malayi | nuclear receptor RXR | 0.0021 | 0.0021 | 0.0079 |
Echinococcus granulosus | Niemann Pick C1 protein | 0.0137 | 0.1522 | 0.1657 |
Brugia malayi | jmjC domain containing protein | 0.0062 | 0.0548 | 0.2003 |
Loa Loa (eye worm) | hypothetical protein | 0.005 | 0.0397 | 0.1453 |
Echinococcus granulosus | muscleblind protein | 0.0145 | 0.1632 | 0.1776 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.0041 | 0.027 | 0.1193 |
Schistosoma mansoni | cellular tumor antigen P53 | 0.0049 | 0.0379 | 0.0413 |
Echinococcus multilocularis | musashi | 0.003 | 0.0132 | 0.0132 |
Onchocerca volvulus | 0.0047 | 0.0353 | 0.1902 | |
Loa Loa (eye worm) | hypothetical protein | 0.0145 | 0.1632 | 0.597 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0041 | 0.027 | 0.0989 |
Schistosoma mansoni | hypothetical protein | 0.0049 | 0.0379 | 0.0413 |
Echinococcus multilocularis | sterol regulatory element binding protein | 0.0041 | 0.0277 | 0.0277 |
Schistosoma mansoni | gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 | 0.0141 | 0.1576 | 0.1715 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.027 | 0.0989 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0041 | 0.027 | 0.0294 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0041 | 0.027 | 0.0294 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0021 | 0.0079 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.027 | 0.0989 |
Loa Loa (eye worm) | hypothetical protein | 0.0119 | 0.1292 | 0.4727 |
Echinococcus granulosus | nuclear receptor subfamily 1 group D | 0.0021 | 0.0021 | 0.0023 |
Trypanosoma brucei | mitochondrial DNA polymerase beta | 0.0296 | 0.3589 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0049 | 0.0379 | 0.0413 |
Entamoeba histolytica | peptidyl-prolyl cis-trans isomerase, putative | 0.0038 | 0.0242 | 0.2453 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0052 | 0.0425 | 0.1185 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0041 | 0.027 | 0.0989 |
Toxoplasma gondii | hypothetical protein | 0.0048 | 0.0363 | 0.8531 |
Echinococcus multilocularis | nuclear receptor subfamily 1 group D | 0.0021 | 0.0021 | 0.0021 |
Schistosoma mansoni | hypothetical protein | 0.0047 | 0.0353 | 0.0384 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0041 | 0.027 | 0.0294 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0021 | 0.0079 |
Mycobacterium tuberculosis | NAD(P)H quinone reductase LpdA | 0.0133 | 0.1474 | 0.8335 |
Schistosoma mansoni | survival motor neuron protein | 0.0047 | 0.0353 | 0.0384 |
Entamoeba histolytica | acetyltransferase, GNAT family | 0.0038 | 0.0237 | 0.2397 |
Echinococcus multilocularis | tar DNA binding protein | 0.0067 | 0.0616 | 0.0616 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.003 | 0.0132 | 0.0483 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.027 | 0.0989 |
Loa Loa (eye worm) | hypothetical protein | 0.023 | 0.2734 | 1 |
Leishmania major | peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative | 0.0038 | 0.0242 | 0.0675 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0021 | 0.0021 | 0.0079 |
Echinococcus granulosus | survival motor neuron protein 1 | 0.023 | 0.2734 | 0.2975 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.0132 | 0.0483 |
Loa Loa (eye worm) | TAR-binding protein | 0.0067 | 0.0616 | 0.2255 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.027 | 0.0989 |
Trypanosoma brucei | trypanothione reductase | 0.0052 | 0.0425 | 0.1185 |
Brugia malayi | RNA binding protein | 0.0067 | 0.0616 | 0.2255 |
Schistosoma mansoni | tar DNA-binding protein | 0.0067 | 0.0616 | 0.0671 |
Loa Loa (eye worm) | nuclear hormone receptor-like 1 | 0.0021 | 0.0021 | 0.0079 |
Echinococcus multilocularis | Transcription factor, JmjC domain containing protein | 0.0062 | 0.0548 | 0.0548 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0062 | 0.0548 | 0.0596 |
Mycobacterium tuberculosis | Probable dehydrogenase | 0.012 | 0.13 | 0.7352 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.0051 | 0.0402 | 0.1119 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.014 | 0.1563 | 0.4355 |
Echinococcus granulosus | tumor protein p63 | 0.0334 | 0.4094 | 0.4455 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0041 | 0.027 | 0.0294 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0288 | 0.3486 | 0.3486 |
Treponema pallidum | exodeoxyribonuclease (exoA) | 0.002 | 0 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0247 | 0.2958 | 0.322 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0049 | 0.0379 | 0.1388 |
Brugia malayi | Niemann-Pick C1 protein precursor | 0.0096 | 0.0988 | 0.3614 |
Echinococcus multilocularis | survival motor neuron protein 1 | 0.023 | 0.2734 | 0.2734 |
Trichomonas vaginalis | rotamase, putative | 0.0039 | 0.0254 | 0.9029 |
Brugia malayi | TAR-binding protein | 0.0067 | 0.0616 | 0.2255 |
Schistosoma mansoni | thyroid hormone receptor | 0.0288 | 0.3486 | 0.3794 |
Loa Loa (eye worm) | hypothetical protein | 0.0155 | 0.1756 | 0.6422 |
Schistosoma mansoni | tar DNA-binding protein | 0.0067 | 0.0616 | 0.0671 |
Schistosoma mansoni | microtubule-associated protein tau | 0.0726 | 0.9188 | 1 |
Schistosoma mansoni | rotamase | 0.0039 | 0.0254 | 0.0277 |
Mycobacterium tuberculosis | Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras | 0.0133 | 0.1474 | 0.8335 |
Echinococcus granulosus | expressed conserved protein | 0.009 | 0.0912 | 0.0993 |
Loa Loa (eye worm) | RNA binding protein | 0.0067 | 0.0616 | 0.2255 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0155 | 0.1756 | 0.6422 |
Plasmodium falciparum | glutathione reductase | 0.0052 | 0.0425 | 1 |
Echinococcus multilocularis | expressed protein | 0.0039 | 0.0254 | 0.0254 |
Trypanosoma brucei | mitochondrial DNA polymerase beta-PAK | 0.014 | 0.1563 | 0.4355 |
Schistosoma mansoni | niemann-pick C1 (NPC1) | 0.0097 | 0.1007 | 0.1096 |
Plasmodium vivax | histone acetyltransferase GCN5, putative | 0.0041 | 0.0282 | 0.6622 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0041 | 0.027 | 0.0989 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0041 | 0.027 | 0.0989 |
Giardia lamblia | Histone acetyltransferase GCN5 | 0.0038 | 0.0237 | 1 |
Echinococcus multilocularis | Mitotic checkpoint protein PRCC, C terminal | 0.0247 | 0.2958 | 0.2958 |
Entamoeba histolytica | hypothetical protein | 0.0071 | 0.0661 | 0.6686 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.027 | 0.0989 |
Leishmania major | mitochondrial DNA polymerase beta-PAK, putative | 0.014 | 0.1563 | 0.4355 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.027 | 0.0989 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0041 | 0.027 | 0.0989 |
Schistosoma mansoni | hypothetical protein | 0.0188 | 0.219 | 0.2383 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0277 | 0.1013 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.0379 | 0.1388 |
Brugia malayi | hypothetical protein | 0.0071 | 0.0661 | 0.2416 |
Brugia malayi | Pin1-type peptidyl-prolyl cis-trans isomerase, BmPin1 | 0.0039 | 0.0254 | 0.093 |
Toxoplasma gondii | thioredoxin reductase | 0.0052 | 0.0425 | 1 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0041 | 0.027 | 0.0294 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0041 | 0.027 | 0.0294 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta, putative | 0.0296 | 0.3589 | 1 |
Trypanosoma brucei | peptidyl-prolyl cis-trans isomerase/rotamase, putative | 0.0038 | 0.0242 | 0.0675 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta, putative | 0.0296 | 0.3589 | 1 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0071 | 0.0661 | 0.0719 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0067 | 0.0616 | 0.2255 |
Echinococcus multilocularis | lamin | 0.003 | 0.0132 | 0.0132 |
Schistosoma mansoni | thyroid hormone receptor | 0.0288 | 0.3486 | 0.3794 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.027 | 0.0989 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.003 | 0.0132 | 0.0483 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0041 | 0.027 | 0.0294 |
Brugia malayi | jmjC domain containing protein | 0.0062 | 0.0548 | 0.2003 |
Entamoeba histolytica | hypothetical protein | 0.0071 | 0.0661 | 0.6686 |
Echinococcus granulosus | lamin | 0.003 | 0.0132 | 0.0144 |
Schistosoma mansoni | hypothetical protein | 0.004 | 0.0258 | 0.0281 |
Schistosoma mansoni | hypothetical protein | 0.0188 | 0.219 | 0.2383 |
Loa Loa (eye worm) | acetyltransferase | 0.0141 | 0.1576 | 0.5765 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0021 | 0.0079 |
Trypanosoma cruzi | peptidyl-prolyl cis-trans isomerase | 0.0038 | 0.0242 | 0.0675 |
Brugia malayi | Muscleblind-like protein | 0.0145 | 0.1632 | 0.597 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0041 | 0.027 | 0.027 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0049 | 0.0379 | 0.0379 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0156 | 0.1769 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0041 | 0.027 | 0.0989 |
Echinococcus granulosus | Niemann Pick C1 protein | 0.0096 | 0.0988 | 0.1075 |
Echinococcus granulosus | intermediate filament protein | 0.003 | 0.0132 | 0.0144 |
Plasmodium vivax | glutathione reductase, putative | 0.0052 | 0.0425 | 1 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.0041 | 0.027 | 0.1193 |
Schistosoma mansoni | tar DNA-binding protein | 0.0067 | 0.0616 | 0.0671 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0041 | 0.027 | 0.0989 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0021 | 0.0021 | 0.0079 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0041 | 0.027 | 0.0294 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0041 | 0.027 | 0.0989 |
Echinococcus multilocularis | lysine specific demethylase 5A | 0.0062 | 0.0548 | 0.0548 |
Echinococcus granulosus | thioredoxin glutathione reductase | 0.0052 | 0.0425 | 0.0463 |
Loa Loa (eye worm) | hypothetical protein | 0.0106 | 0.1119 | 0.4092 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0041 | 0.027 | 0.0989 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0041 | 0.027 | 0.0989 |
Loa Loa (eye worm) | intermediate filament protein | 0.003 | 0.0132 | 0.0483 |
Schistosoma mansoni | hypothetical protein | 0.0049 | 0.0379 | 0.0413 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0155 | 0.1756 | 0.6422 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0041 | 0.027 | 0.0989 |
Echinococcus granulosus | histone acetyltransferase KAT2B | 0.0137 | 0.1525 | 0.1659 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0062 | 0.0548 | 0.2003 |
Schistosoma mansoni | hypothetical protein | 0.004 | 0.0258 | 0.0281 |
Echinococcus granulosus | Transcription factor JmjC domain containing protein | 0.0062 | 0.0548 | 0.0596 |
Mycobacterium ulcerans | hypothetical protein | 0.0156 | 0.1769 | 1 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0041 | 0.027 | 0.0294 |
Loa Loa (eye worm) | hypothetical protein | 0.0119 | 0.1292 | 0.4727 |
Mycobacterium tuberculosis | Probable membrane NADH dehydrogenase NdhA | 0.012 | 0.13 | 0.7352 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.0379 | 0.1388 |
Schistosoma mansoni | tar DNA-binding protein | 0.0067 | 0.0616 | 0.0671 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0041 | 0.027 | 0.0294 |
Plasmodium vivax | thioredoxin reductase, putative | 0.0052 | 0.0425 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0049 | 0.0379 | 0.0413 |
Brugia malayi | hypothetical protein | 0.0119 | 0.1292 | 0.4727 |
Echinococcus granulosus | Mitotic checkpoint protein PRCC C terminal | 0.0247 | 0.2958 | 0.322 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0041 | 0.027 | 0.0294 |
Loa Loa (eye worm) | Pin1-type peptidyl-prolyl cis-trans isomerase | 0.0039 | 0.0254 | 0.093 |
Brugia malayi | ecdysteroid receptor | 0.0041 | 0.027 | 0.0989 |
Echinococcus granulosus | histone acetyltransferase KAT2B | 0.0041 | 0.0282 | 0.0307 |
Trypanosoma cruzi | DNA polymerase beta thumb, putative | 0.0042 | 0.0283 | 0.079 |
Schistosoma mansoni | hypothetical protein | 0.004 | 0.0258 | 0.0281 |
Loa Loa (eye worm) | hypothetical protein | 0.0145 | 0.1632 | 0.597 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0041 | 0.027 | 0.027 |
Echinococcus granulosus | lamin dm0 | 0.003 | 0.0132 | 0.0144 |
Mycobacterium tuberculosis | Probable NADH dehydrogenase Ndh | 0.012 | 0.13 | 0.7352 |
Trypanosoma brucei | DNA polymerase beta thumb, putative | 0.0042 | 0.0283 | 0.079 |
Echinococcus granulosus | geminin | 0.0188 | 0.219 | 0.2383 |
Echinococcus granulosus | Protein patched homolog 1 | 0.0041 | 0.0277 | 0.0301 |
Schistosoma mansoni | nuclear hormone receptor | 0.0041 | 0.027 | 0.0294 |
Schistosoma mansoni | coup transcription factor | 0.0041 | 0.027 | 0.0294 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0041 | 0.027 | 0.027 |
Brugia malayi | steroid hormone receptor | 0.0041 | 0.027 | 0.0989 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.027 | 0.0989 |
Brugia malayi | glutathione reductase | 0.0052 | 0.0425 | 0.1556 |
Brugia malayi | nuclear receptor NHR-88 | 0.0041 | 0.027 | 0.0989 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0041 | 0.027 | 0.0989 |
Schistosoma mansoni | tar DNA-binding protein | 0.0067 | 0.0616 | 0.0671 |
Plasmodium falciparum | thioredoxin reductase | 0.0052 | 0.0425 | 1 |
Echinococcus multilocularis | muscleblind protein | 0.0145 | 0.1632 | 0.1632 |
Mycobacterium tuberculosis | Probable reductase | 0.012 | 0.13 | 0.7352 |
Trypanosoma cruzi | peptidyl-prolyl cis-trans isomerase | 0.0038 | 0.0242 | 0.0675 |
Toxoplasma gondii | histone lysine acetyltransferase GCN5-A | 0.0041 | 0.0282 | 0.6622 |
Echinococcus granulosus | lysine specific demethylase 5A | 0.0062 | 0.0548 | 0.0596 |
Echinococcus multilocularis | Niemann Pick C1 protein | 0.0096 | 0.0988 | 0.0988 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0041 | 0.027 | 0.0989 |
Entamoeba histolytica | Niemann-Pick C1 protein, putative | 0.0096 | 0.0988 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0039 | 0.0254 | 0.9029 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0133 | 0.1474 | 0.8335 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0049 | 0.0379 | 0.1388 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.0042 | 0.0283 | 0.079 |
Brugia malayi | acetyltransferase, GNAT family protein | 0.0141 | 0.1576 | 0.5765 |
Schistosoma mansoni | hypothetical protein | 0.0071 | 0.0661 | 0.0719 |
Echinococcus multilocularis | GPCR, family 2 | 0.0049 | 0.0379 | 0.0379 |
Echinococcus granulosus | sterol regulatory element binding protein | 0.0041 | 0.0277 | 0.0301 |
Echinococcus granulosus | microtubule associated protein 2 | 0.0726 | 0.9188 | 1 |
Echinococcus granulosus | FTZ F1 alpha | 0.0041 | 0.027 | 0.0294 |
Echinococcus multilocularis | protein dispatched 1 | 0.0047 | 0.0353 | 0.0353 |
Loa Loa (eye worm) | glutathione reductase | 0.0052 | 0.0425 | 0.1556 |
Brugia malayi | Thioredoxin reductase | 0.0052 | 0.0425 | 0.1556 |
Toxoplasma gondii | peptidylprolyl isomerase | 0.0038 | 0.0242 | 0.5695 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0041 | 0.027 | 0.0989 |
Schistosoma mansoni | jumonji domain containing protein | 0.0062 | 0.0548 | 0.0596 |
Echinococcus multilocularis | protein patched | 0.0041 | 0.0277 | 0.0277 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0021 | 0.0021 | 0.0023 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0041 | 0.027 | 0.027 |
Mycobacterium tuberculosis | Putative ferredoxin reductase | 0.012 | 0.13 | 0.7352 |
Echinococcus multilocularis | gcn5proteinral control of amino acid synthesis | 0.0141 | 0.1576 | 0.1576 |
Brugia malayi | hypothetical protein | 0.0021 | 0.0021 | 0.0079 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0021 | 0.0079 |
Mycobacterium tuberculosis | Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB | 0.012 | 0.13 | 0.7352 |
Schistosoma mansoni | lamin | 0.003 | 0.0132 | 0.0144 |
Echinococcus granulosus | GPCR family 2 | 0.0049 | 0.0379 | 0.0413 |
Leishmania major | trypanothione reductase | 0.0052 | 0.0425 | 0.1185 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0041 | 0.027 | 0.0294 |
Plasmodium falciparum | histone acetyltransferase GCN5 | 0.0038 | 0.0237 | 0.5566 |
Trypanosoma cruzi | DNA polymerase beta thumb, putative | 0.0042 | 0.0283 | 0.079 |
Onchocerca volvulus | Huntingtin homolog | 0.0119 | 0.1292 | 1 |
Echinococcus multilocularis | muscleblind protein 1 | 0.0145 | 0.1632 | 0.1632 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0041 | 0.027 | 0.0989 |
Echinococcus multilocularis | expressed conserved protein | 0.009 | 0.0912 | 0.0912 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0041 | 0.0277 | 0.9832 |
Brugia malayi | hypothetical protein | 0.023 | 0.2734 | 1 |
Onchocerca volvulus | Huntingtin homolog | 0.0119 | 0.1292 | 1 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0041 | 0.027 | 0.027 |
Entamoeba histolytica | hypothetical protein | 0.0071 | 0.0661 | 0.6686 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0155 | 0.1756 | 0.6422 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0041 | 0.027 | 0.0989 |
Schistosoma mansoni | hypothetical protein | 0.004 | 0.0258 | 0.0281 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0041 | 0.027 | 0.027 |
Onchocerca volvulus | Bile acid receptor homolog | 0.0041 | 0.027 | 0.1193 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0041 | 0.027 | 0.0294 |
Onchocerca volvulus | 0.0049 | 0.0379 | 0.2132 | |
Echinococcus granulosus | tar DNA binding protein | 0.0067 | 0.0616 | 0.0671 |
Onchocerca volvulus | 0.0041 | 0.027 | 0.1193 | |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0041 | 0.027 | 0.0989 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0041 | 0.027 | 0.0989 |
Mycobacterium leprae | DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE | 0.0133 | 0.1474 | 1 |
Schistosoma mansoni | lamin | 0.003 | 0.0132 | 0.0144 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0041 | 0.027 | 0.0989 |
Echinococcus multilocularis | thioredoxin glutathione reductase | 0.0052 | 0.0425 | 0.0425 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0049 | 0.0379 | 0.0413 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0041 | 0.027 | 0.0294 |
Brugia malayi | intermediate filament protein | 0.003 | 0.0132 | 0.0483 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0062 | 0.0548 | 0.0596 |
Schistosoma mansoni | ecdysone-induced protein 78c (dr-78) | 0.0021 | 0.0021 | 0.0023 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0041 | 0.027 | 0.0989 |
Leishmania major | mitochondrial DNA polymerase beta | 0.0296 | 0.3589 | 1 |
Echinococcus multilocularis | tumor protein p63 | 0.0334 | 0.4094 | 0.4094 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0041 | 0.027 | 0.0989 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0041 | 0.027 | 0.027 |
Trichomonas vaginalis | rotamase, putative | 0.0038 | 0.0242 | 0.8601 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0041 | 0.027 | 0.0294 |
Schistosoma mansoni | hypothetical protein | 0.0106 | 0.1119 | 0.1217 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0071 | 0.0661 | 0.0661 |
Echinococcus granulosus | expressed protein | 0.0039 | 0.0254 | 0.0277 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0125 | 0.0457 |
Trichomonas vaginalis | cat eye syndrome critical region protein 2, cscr2, putative | 0.0041 | 0.0282 | 1 |
Schistosoma mansoni | intermediate filament proteins | 0.003 | 0.0132 | 0.0144 |
Brugia malayi | Iron-sulfur cluster assembly accessory protein | 0.0047 | 0.0353 | 0.129 |
Mycobacterium tuberculosis | NADPH-dependent mycothiol reductase Mtr | 0.0052 | 0.0425 | 0.2406 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0106 | 0.1119 | 0.4092 |
Brugia malayi | hypothetical protein | 0.0021 | 0.0021 | 0.0079 |
Echinococcus multilocularis | geminin | 0.0188 | 0.219 | 0.219 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0021 | 0.0079 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0049 | 0.0379 | 0.1388 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0049 | 0.0379 | 0.0379 |
Toxoplasma gondii | histone lysine acetyltransferase GCN5-B | 0.0041 | 0.0282 | 0.6622 |
Echinococcus multilocularis | lamin dm0 | 0.003 | 0.0132 | 0.0132 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0041 | 0.027 | 0.0989 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0041 | 0.027 | 0.0989 |
Loa Loa (eye worm) | abnormal chemotaxis protein 14 | 0.0041 | 0.0277 | 0.1013 |
Brugia malayi | CHE-14 protein | 0.0041 | 0.0277 | 0.1013 |
Trichomonas vaginalis | bromodomain-containing protein, putative | 0.0041 | 0.0282 | 1 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0041 | 0.027 | 0.0294 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.