TDR Targets

Basic information

Technical information

Name: Unnamed compound
MW: 615.696 | Formula: C29H50N3O9P
H donors: 1 H acceptors: 3 LogP: 5.9 Rotable bonds: 24
Rule of 5 violations (Lipinski): 2
SMILES: CCCCCCCCCCCCCCCC(=O)OC1C(COP(=O)(OCCOCC)O)OC2C1Oc1n2ccc(=N)n1
InChi: 1S/C29H50N3O9P/c1-3-5-6-7-8-9-10-11-12-13-14-15-16-17-25(33)40-26-23(22-38-42(34,35)37-21-20-36-4-2)39-28-27(26)41-29-31-24(30)18-19-32(28)29/h18-19,23,26-28,30H,3-17,20-22H2,1-2H3,(H,34,35)
InChiKey: GWQMFMNUILJXAN-UHFFFAOYSA-N

Network

Hover on a compound node to display the structore

Target Layer

Model Organisms

Species	Viewmode
Arabidopsis thaliana
Caenorhabditis elegans
Dictyostelium discoideum
Drosophila melanogaster
Escherichia coli
Homo sapiens
Mus musculus
Oryza sativa
Saccharomyces cerevisiae
Schmidtea mediterranea
Other organisms

TDR Pathogens:

Species	Viewmode
Brugia malayi
Chlamydia trachomatis
Echinococcus granulosus
Entamoeba histolytica
Echinococcus multilocularis
Giardia lamblia
Leishmania major
Loa Loa (eye worm)
Mycobacterium leprae
Mycobacterium tuberculosis
Mycobacterium ulcerans
Onchocerca volvulus
Plasmodium falciparum
Plasmodium vivax
Schistosoma mansoni
Trypanosoma brucei
Trypanosoma cruzi
Toxoplasma gondii
Treponema pallidum
Trichomonas vaginalis
Wolbachia endosymbiont of Brugia malayi

Other Pathogens:

Species	Viewmode
Babesia bovis
Candida albicans
Cryptosporidium hominis
Cryptosporidium parvum
Leishmania braziliensis
Leishmania donovani
Leishmania infantum
Leishmania mexicana
Neospora caninum
Plasmodium berghei
Plasmodium knowlesi
Plasmodium yoelii
Schistosoma japonicum
Trypanosoma brucei gambiense
Trypanosoma congolense
Theileria parva

Compound Layer

This is a work in progress. Come back soon to try this features!

Clustering layers

This is a work in progress. Come back soon to try this features!

Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology

No druggable targets predicted by orthology data

By sequence similarity to non orthologous known druggable targets

No druggable targets predicted by sequence similarity

Ranking Plot

Putative Targets List

Species	Potential target	Raw	Global	Species
Echinococcus granulosus	cytoplasmic intermediate filament protein	0.0043	0.0011	0.0017
Entamoeba histolytica	SH2-protein kinase domain containing protein	0.0069	0.0734	0.0722
Brugia malayi	hypothetical protein	0.0055	0.0348	0.0465
Brugia malayi	SH2 domain containing protein	0.0054	0.031	0.0415
Loa Loa (eye worm)	variant SH3 domain-containing protein	0.0106	0.1781	0.1781
Loa Loa (eye worm)	tubulin gamma chain	0.0148	0.2954	0.2954
Loa Loa (eye worm)	hypothetical protein	0.0251	0.5831	0.5831
Echinococcus granulosus	lamin	0.009	0.1307	0.1965
Echinococcus granulosus	neuropeptide Y receptor	0.0055	0.0348	0.0523
Echinococcus multilocularis	tubulin alpha 1C chain	0.0203	0.4494	0.6754
Echinococcus multilocularis	peptide (allatostatin:somatostatin)	0.0055	0.0348	0.0523
Echinococcus granulosus	tubulin alpha 1C chain	0.0203	0.4494	0.6754
Brugia malayi	neuropeptide F receptor	0.0055	0.0348	0.0465
Brugia malayi	Tubulin alpha chain	0.0064	0.0605	0.0808
Brugia malayi	Tubulin gamma chain	0.0148	0.2954	0.3946
Loa Loa (eye worm)	TK/FER protein kinase	0.0069	0.0734	0.0734
Brugia malayi	intermediate filament protein	0.009	0.1307	0.1746
Brugia malayi	Variant SH3 domain containing protein	0.0053	0.0273	0.0365
Schistosoma mansoni	peptide (allatostatin/somatostatin)-like receptor	0.0055	0.0348	0.0323
Echinococcus granulosus	breast cancer anti estrogen resistance protein	0.0053	0.0273	0.041
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0055	0.0348	0.0323
Loa Loa (eye worm)	TK protein kinase	0.0127	0.2342	0.2342
Echinococcus granulosus	hematopoietic lineage cell specific protein	0.0053	0.0273	0.041
Schistosoma mansoni	opsin-like receptor	0.0055	0.0348	0.0323
Schistosoma mansoni	hypothetical protein	0.0055	0.0348	0.0323
Loa Loa (eye worm)	hypothetical protein	0.0054	0.031	0.031
Schistosoma mansoni	suppressor of cytokine signaling	0.0054	0.031	0.0272
Brugia malayi	RhoGAP domain containing protein	0.0054	0.031	0.0415
Echinococcus granulosus	tubulin alpha chain	0.0203	0.4494	0.6754
Schistosoma mansoni	amine GPCR	0.0055	0.0348	0.0323
Echinococcus granulosus	intermediate filament protein	0.009	0.1307	0.1965
Loa Loa (eye worm)	protein-tyrosine phosphatase	0.0054	0.031	0.031
Schistosoma mansoni	vav2	0.0054	0.031	0.0272
Echinococcus granulosus	Spectrin alpha actinin	0.0053	0.0273	0.041
Plasmodium vivax	tubulin epsilon chain, putative	0.0148	0.2954	0.3883
Brugia malayi	hypothetical protein	0.0251	0.5831	0.7789
Loa Loa (eye worm)	guanylate kinase	0.0053	0.0273	0.0273
Loa Loa (eye worm)	hypothetical protein	0.0251	0.5831	0.5831
Onchocerca volvulus		0.0055	0.0348	0.0135
Schistosoma mansoni	hypothetical protein	0.0055	0.0348	0.0323
Echinococcus granulosus	tyrosine protein kinase Src64B	0.0179	0.3813	0.5729
Loa Loa (eye worm)	BEN-1 protein	0.0281	0.6655	0.6655
Echinococcus multilocularis	suppressor of cytokine signaling 7	0.0054	0.031	0.0466
Echinococcus granulosus	Tubulin beta 2C chain	0.0281	0.6655	1
Echinococcus granulosus	rhodopsin orphan GPCR	0.0055	0.0348	0.0523
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0055	0.0348	0.0323
Loa Loa (eye worm)	SRC-1	0.0179	0.3813	0.3813
Brugia malayi	hypothetical protein	0.0069	0.0734	0.098
Echinococcus granulosus	somatostatin receptor	0.0055	0.0348	0.0523
Echinococcus multilocularis	tubulin alpha chain	0.0203	0.4494	0.6754
Echinococcus granulosus	serotonin receptor	0.0055	0.0348	0.0523
Echinococcus granulosus	tyrosine kinase	0.0069	0.0734	0.1103
Brugia malayi	Blistered cuticle protein 3	0.0251	0.5831	0.7789
Loa Loa (eye worm)	hypothetical protein	0.0055	0.0348	0.0348
Plasmodium falciparum	alpha tubulin 2	0.0203	0.4494	0.6429
Trypanosoma cruzi	beta tubulin, putative	0.0281	0.6655	1
Giardia lamblia	Beta tubulin	0.0281	0.6655	1
Schistosoma mansoni	sorbin	0.0053	0.0273	0.0221
Echinococcus multilocularis	rho guanine nucleotide exchange factor 7	0.0053	0.0273	0.041
Schistosoma mansoni	adenoreceptor	0.0055	0.0348	0.0323
Trypanosoma brucei	alpha tubulin	0.0203	0.4494	0.6615
Brugia malayi	Variant SH3 domain containing protein	0.0053	0.0273	0.0365
Schistosoma mansoni	eps8-related protein	0.0053	0.0273	0.0221
Trypanosoma brucei	alpha tubulin	0.0203	0.4494	0.6615
Brugia malayi	G-protein-linked acetylcholine receptor protein 2, putative	0.0055	0.0348	0.0465
Brugia malayi	protein-tyrosine kinase	0.0127	0.2342	0.3128
Leishmania major	alpha tubulin	0.0203	0.4494	0.6615
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0055	0.0348	0.0523
Loa Loa (eye worm)	TK/FER protein kinase	0.0069	0.0734	0.0734
Loa Loa (eye worm)	p53BP2	0.0053	0.0273	0.0273
Echinococcus multilocularis	tubulin alpha chain	0.0203	0.4494	0.6754
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0055	0.0348	0.0323
Onchocerca volvulus		0.0055	0.0348	0.0135
Onchocerca volvulus		0.0054	0.031	0.0067
Loa Loa (eye worm)	tubulin beta chain	0.0281	0.6655	0.6655
Loa Loa (eye worm)	alpha-tubulin isotype 2	0.0139	0.2692	0.2692
Echinococcus multilocularis	tyrosine protein kinase Fyn	0.0179	0.3813	0.5729
Leishmania major	delta tubulin, putative	0.0064	0.0605	0.052
Echinococcus granulosus	arf GAP with SH3 domain ANK repeat and PH	0.0053	0.0273	0.041
Echinococcus granulosus	neuropeptide receptor	0.0055	0.0348	0.0523
Schistosoma mansoni	adapter molecule crk	0.0106	0.1781	0.2266
Loa Loa (eye worm)	hypothetical protein	0.0055	0.0348	0.0348
Brugia malayi	tubulin alpha chain - mouse	0.0203	0.4494	0.6004
Echinococcus granulosus	tubulin alpha 3 chain	0.0203	0.4494	0.6754
Loa Loa (eye worm)	tubulin beta-2A chain	0.0281	0.6655	0.6655
Brugia malayi	Serotonin/octopamine receptor family protein 7	0.0055	0.0348	0.0465
Loa Loa (eye worm)	glutaminase	0.031	0.7486	0.7486
Echinococcus granulosus	tensin	0.0054	0.031	0.0466
Brugia malayi	Dopamine receptor protein 1, putative (partial)	0.0055	0.0348	0.0465
Brugia malayi	Variant SH3 domain containing protein	0.0106	0.1781	0.2379
Brugia malayi	Protein kinase domain containing protein	0.0069	0.0734	0.098
Leishmania major	beta tubulin	0.0281	0.6655	1
Echinococcus granulosus	SHC transforming protein 3	0.0054	0.031	0.0466
Brugia malayi	Variant SH3 domain containing protein	0.0054	0.031	0.0415
Schistosoma mansoni	tyrosine kinase	0.0122	0.2205	0.284
Brugia malayi	neuropeptide F receptor	0.0055	0.0348	0.0465
Brugia malayi	hypothetical protein	0.0055	0.0348	0.0465
Echinococcus granulosus	g-protein coupled receptor	0.0055	0.0348	0.0523
Brugia malayi	Tyrosine-protein kinase abl-1	0.0122	0.2205	0.2945
Schistosoma mansoni	histamine-responsive GPCR (AAF21638)	0.0055	0.0348	0.0323
Brugia malayi	hypothetical protein	0.0054	0.031	0.0415
Schistosoma mansoni	myosin xvIII	0.0055	0.0348	0.0323
Loa Loa (eye worm)	hypothetical protein	0.0053	0.0273	0.0273
Trichomonas vaginalis	tubulin beta chain, putative	0.0281	0.6655	0.8848
Brugia malayi	Dopamine receptor protein 2	0.0055	0.0348	0.0465
Brugia malayi	cytoplasmic intermediate filament protein	0.0048	0.0144	0.0193
Echinococcus multilocularis	tyrosine protein kinase Srms	0.0127	0.2342	0.3519
Echinococcus granulosus	tyrosine kinase	0.0127	0.2342	0.3519
Echinococcus multilocularis	tyrosine protein kinase lyn tyrosine protein kinase blk	0.0179	0.3813	0.5729
Echinococcus multilocularis	tubulin alpha	0.0148	0.2954	0.4439
Brugia malayi	Protein kinase domain containing protein	0.0069	0.0734	0.098
Echinococcus multilocularis	slit robo rho gtpase activating protein 1	0.0053	0.0273	0.041
Trichomonas vaginalis	tubulin epsilon chain, putative	0.0281	0.6655	0.8848
Echinococcus granulosus	3'partial\|tyrosine protein kinase Fgr	0.0179	0.3813	0.5729
Leishmania major	beta tubulin	0.0281	0.6655	1
Loa Loa (eye worm)	hypothetical protein	0.0251	0.5831	0.5831
Echinococcus granulosus	tubulin alpha 3 chain	0.0203	0.4494	0.6754
Brugia malayi	SH3 domain containing protein	0.0053	0.0273	0.0365
Schistosoma mansoni	hypothetical protein	0.0054	0.031	0.0272
Onchocerca volvulus		0.0055	0.0348	0.0135
Toxoplasma gondii	alpha-tubulin I, putative	0.0203	0.4494	0.414
Echinococcus multilocularis	lamin	0.009	0.1307	0.1965
Echinococcus multilocularis	neuropeptides capa receptor	0.0055	0.0348	0.0523
Loa Loa (eye worm)	hypothetical protein	0.0053	0.0273	0.0273
Onchocerca volvulus		0.009	0.1307	0.1861
Loa Loa (eye worm)	G-protein coupled receptor	0.0055	0.0348	0.0348
Trichomonas vaginalis	tubulin alpha chain, putative	0.0084	0.1151	0.1218
Schistosoma mansoni	tubulin subunit alpha	0.0203	0.4494	0.5944
Echinococcus multilocularis	peroxisome assembly protein 26	0.0203	0.4494	0.6754
Mycobacterium ulcerans	glutaminase	0.031	0.7486	1
Schistosoma mansoni	opsin-like receptor	0.0055	0.0348	0.0323
Onchocerca volvulus		0.0069	0.0734	0.0829
Onchocerca volvulus		0.0251	0.5831	1
Echinococcus granulosus	rhodopsin orphan GPCR	0.0055	0.0348	0.0523
Schistosoma mansoni	amine GPCR	0.0055	0.0348	0.0323
Schistosoma mansoni	tyrosine kinase	0.0069	0.0734	0.0846
Onchocerca volvulus		0.0055	0.0348	0.0135
Plasmodium falciparum	tubulin gamma chain	0.0148	0.2954	0.3883
Brugia malayi	Animal haem peroxidase family protein	0.0251	0.5831	0.7789
Trichomonas vaginalis	tubulin, putative	0.0084	0.1151	0.1218
Echinococcus multilocularis	fch and double sh3 domains protein 2	0.0053	0.0273	0.041
Brugia malayi	G-protein coupled receptor	0.0055	0.0348	0.0465
Toxoplasma gondii	alpha tubulin TUBA1	0.0203	0.4494	0.414
Loa Loa (eye worm)	protein kinase C and casein kinase substrate in neurons protein 2	0.0053	0.0273	0.0273
Trichomonas vaginalis	tubulin gamma chain, putative	0.0064	0.0605	0.046
Schistosoma mansoni	neuropeptide F-like receptor	0.0055	0.0348	0.0323
Loa Loa (eye worm)	hypothetical protein	0.0055	0.0348	0.0348
Leishmania major	beta tubulin	0.0281	0.6655	1
Echinococcus multilocularis	alpha 1A adrenergic receptor	0.0055	0.0348	0.0523
Loa Loa (eye worm)	hypothetical protein	0.0055	0.0348	0.0348
Loa Loa (eye worm)	hypothetical protein	0.0053	0.0273	0.0273
Schistosoma mansoni	growth hormone secretagogue receptor	0.0055	0.0348	0.0323
Schistosoma mansoni	tensin	0.0054	0.031	0.0272
Onchocerca volvulus		0.0055	0.0348	0.0135
Schistosoma mansoni	formin binding protein and related proteins	0.0053	0.0273	0.0221
Schistosoma mansoni	neuropeptide receptor	0.0055	0.0348	0.0323
Brugia malayi	Variant SH3 domain containing protein	0.0053	0.0273	0.0365
Toxoplasma gondii	beta-1 tubulin, putative	0.0281	0.6655	0.6439
Echinococcus granulosus	tyrosine protein kinase Fyn	0.0179	0.3813	0.5729
Loa Loa (eye worm)	TK/FER protein kinase	0.0069	0.0734	0.0734
Echinococcus multilocularis	g protein linked acetylcholine receptor gar 2a	0.0055	0.0348	0.0523
Echinococcus multilocularis	growth factor receptor bound protein 2	0.0106	0.1781	0.2677
Loa Loa (eye worm)	STAT protein	0.0054	0.031	0.031
Plasmodium falciparum	tubulin epsilon chain, putative	0.0148	0.2954	0.3883
Echinococcus multilocularis	phosphatidylinositol 3 kinase regulatory subunit	0.0054	0.031	0.0466
Echinococcus multilocularis	arf GAP with SH3 domain, ANK repeat and PH	0.0053	0.0273	0.041
Echinococcus multilocularis	tubulin alpha chain	0.0203	0.4494	0.6754
Leishmania major	alpha tubulin	0.0203	0.4494	0.6615
Loa Loa (eye worm)	hypothetical protein	0.0055	0.0348	0.0348
Echinococcus granulosus	rhodopsin orphan GPCR	0.0055	0.0348	0.0523
Leishmania major	alpha tubulin	0.0203	0.4494	0.6615
Brugia malayi	SH2 domain containing protein	0.0054	0.031	0.0415
Loa Loa (eye worm)	hypothetical protein	0.0055	0.0348	0.0348
Brugia malayi	Peripheral plasma membrane protein CASK	0.0053	0.0273	0.0365
Echinococcus granulosus	rho guanine nucleotide exchange factor 7	0.0053	0.0273	0.041
Echinococcus multilocularis	tyrosine protein kinase Fgr	0.0179	0.3813	0.5729
Trichomonas vaginalis	tubulin alpha chain, putative	0.0084	0.1151	0.1218
Echinococcus multilocularis	tubulin alpha chain	0.0203	0.4494	0.6754
Trypanosoma cruzi	tubulin gamma chain	0.0148	0.2954	0.4201
Echinococcus granulosus	tyrosine kinase\|tyrosine protein kinase Fyn	0.0127	0.2342	0.3519
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0055	0.0348	0.0523
Echinococcus multilocularis	Tubulin beta 2C chain	0.0281	0.6655	1
Leishmania major	gamma-tubulin	0.0148	0.2954	0.4201
Schistosoma mansoni	tubulin subunit beta	0.0064	0.0605	0.0671
Onchocerca volvulus		0.0069	0.0734	0.0829
Schistosoma mansoni	proto-oncogene tyrosine-protein kinase abl1	0.0106	0.1781	0.2266
Schistosoma mansoni	ancient conserved domain protein 2 (cyclin m2)	0.0055	0.0348	0.0323
Echinococcus multilocularis	guanine nucleotide exchange factor VAV2	0.0054	0.031	0.0466
Brugia malayi	Tubulin beta chain	0.0084	0.1151	0.1538
Echinococcus granulosus	biogenic amine 5HT receptor	0.0055	0.0348	0.0523
Echinococcus multilocularis	Tubulin beta 2C chain	0.0281	0.6655	1
Schistosoma mansoni	tensin	0.0054	0.031	0.0272
Echinococcus multilocularis	thyrotropin releasing hormone receptor	0.0055	0.0348	0.0523
Echinococcus granulosus	neuropeptides capa receptor	0.0055	0.0348	0.0523
Echinococcus multilocularis	tubulin subunit TubB	0.0203	0.4494	0.6754
Onchocerca volvulus		0.0055	0.0348	0.0135
Echinococcus granulosus	tubulin beta 1 chain	0.0281	0.6655	1
Onchocerca volvulus		0.0251	0.5831	1
Loa Loa (eye worm)	sex muscle abnormal protein 5	0.0106	0.1781	0.1781
Schistosoma mansoni	biogenic amine receptor	0.0055	0.0348	0.0323
Echinococcus granulosus	G protein coupled 5 hydroxytryptamine receptor	0.0055	0.0348	0.0523
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0055	0.0348	0.0523
Echinococcus multilocularis	neuropeptide s receptor	0.0055	0.0348	0.0523
Echinococcus multilocularis	SH2 domain containing adapter protein F	0.0054	0.031	0.0466
Entamoeba histolytica	tubulin alpha-1 chain	0.0203	0.4494	0.6615
Loa Loa (eye worm)	hypothetical protein	0.0055	0.0348	0.0348
Echinococcus multilocularis	g protein coupled receptor	0.0055	0.0348	0.0523
Schistosoma mansoni	intermediate filament proteins	0.009	0.1307	0.1623
Schistosoma mansoni	protein tyrosine phosphatase n11 (shp2)	0.0054	0.031	0.0272
Loa Loa (eye worm)	hypothetical protein	0.0054	0.031	0.031
Echinococcus multilocularis	Tubulin beta 2C chain	0.0281	0.6655	1
Schistosoma mansoni	nck2/grb4	0.0106	0.1781	0.2266
Echinococcus multilocularis	tensin	0.0054	0.031	0.0466
Schistosoma mansoni	biogenic amine (dopamine) receptor	0.0055	0.0348	0.0323
Loa Loa (eye worm)	hypothetical protein	0.0055	0.0348	0.0348
Echinococcus granulosus	NCK adaptor protein	0.0106	0.1781	0.2677
Echinococcus multilocularis	7TM GPCR, rhodopsin	0.0055	0.0348	0.0523
Loa Loa (eye worm)	tubulin alpha-2 chain	0.0203	0.4494	0.4494
Brugia malayi	Guanylate kinase family protein	0.0053	0.0273	0.0365
Echinococcus multilocularis	g protein coupled receptor	0.0055	0.0348	0.0523
Trichomonas vaginalis	tubulin gamma chain, putative	0.0148	0.2954	0.3717
Echinococcus multilocularis	intersectin 2	0.0053	0.0273	0.041
Loa Loa (eye worm)	hypothetical protein	0.0055	0.0348	0.0348
Echinococcus granulosus	SH2 domain containing protein 7	0.0054	0.031	0.0466
Loa Loa (eye worm)	hypothetical protein	0.0053	0.0273	0.0273
Echinococcus multilocularis	tyrosine protein kinase Btk29A	0.0122	0.2205	0.3313
Loa Loa (eye worm)	hypothetical protein	0.0054	0.031	0.031
Schistosoma mansoni	tyrosine kinase	0.0179	0.3813	0.502
Leishmania major	beta tubulin	0.0281	0.6655	1
Echinococcus granulosus	Tubulin alpha 1 chain	0.0203	0.4494	0.6754
Echinococcus granulosus	rhodopsin orphan GPCR	0.0055	0.0348	0.0523
Onchocerca volvulus		0.0054	0.031	0.0067
Loa Loa (eye worm)	hypothetical protein	0.0055	0.0348	0.0348
Schistosoma mansoni	biogenic amine (octopamine/dopamine) receptor	0.0055	0.0348	0.0323
Loa Loa (eye worm)	hypothetical protein	0.0055	0.0348	0.0348
Echinococcus multilocularis	neuropeptide receptor	0.0055	0.0348	0.0523
Trichomonas vaginalis	conserved hypothetical protein	0.0064	0.0605	0.046
Echinococcus granulosus	g protein coupled receptor	0.0055	0.0348	0.0523
Echinococcus multilocularis	Tubulin alpha 1 chain	0.0203	0.4494	0.6754
Echinococcus multilocularis	neuropeptide receptor A26	0.0055	0.0348	0.0523
Brugia malayi	SH2 domain containing protein	0.0054	0.031	0.0415
Echinococcus granulosus	N chimaerin	0.0054	0.031	0.0466
Echinococcus granulosus	7TM GPCR rhodopsin	0.0055	0.0348	0.0523
Echinococcus granulosus	rhodopsin orphan GPCR	0.0055	0.0348	0.0523
Echinococcus multilocularis	tensin	0.0054	0.031	0.0466
Echinococcus granulosus	beta tubulin	0.0281	0.6655	1
Echinococcus multilocularis	tyrosine kinase	0.0069	0.0734	0.1103
Trichomonas vaginalis	tubulin alpha chain, putative	0.0148	0.2954	0.3717
Echinococcus granulosus	fmrfamide receptor	0.0055	0.0348	0.0523
Echinococcus granulosus	fch and double sh3 domains protein 2	0.0053	0.0273	0.041
Loa Loa (eye worm)	cytokine inducible SH2-containing protein 5	0.0054	0.031	0.031
Loa Loa (eye worm)	protein-tyrosine kinase	0.0053	0.0273	0.0273
Echinococcus multilocularis	G protein coupled receptor 139	0.0055	0.0348	0.0523
Schistosoma mansoni	apoptosis stimulating of P53	0.0053	0.0273	0.0221
Loa Loa (eye worm)	unidentified vitellogenin-linked transcript protein 6	0.0055	0.0348	0.0348
Echinococcus multilocularis	tubulin alpha chain	0.0203	0.4494	0.6754
Loa Loa (eye worm)	hypothetical protein	0.0055	0.0348	0.0348
Onchocerca volvulus	Peroxidase homolog	0.0251	0.5831	1
Echinococcus granulosus	tubulin subunit TubB	0.0203	0.4494	0.6754
Echinococcus granulosus	tyrosine protein phosphatase non receptor type	0.0054	0.031	0.0466
Echinococcus granulosus	tubulin alpha chain	0.0203	0.4494	0.6754
Echinococcus multilocularis	endophilin A3	0.0053	0.0273	0.041
Echinococcus multilocularis	tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase	0.0179	0.3813	0.5729
Schistosoma mansoni	lamin	0.009	0.1307	0.1623
Loa Loa (eye worm)	tubulin beta chain	0.0064	0.0605	0.0605
Schistosoma mansoni	opsin-like receptor	0.0055	0.0348	0.0323
Loa Loa (eye worm)	intermediate filament protein	0.009	0.1307	0.1307
Brugia malayi	hypothetical protein	0.0055	0.0348	0.0465
Schistosoma mansoni	biogenic amine (dopamine) receptor	0.0055	0.0348	0.0323
Schistosoma mansoni	tubulin subunit beta	0.0281	0.6655	0.8873
Echinococcus multilocularis	tubulin alpha 1C chain	0.0203	0.4494	0.6754
Mycobacterium leprae	cell division protein FtsZ	0.0064	0.0605	0.5
Echinococcus granulosus	SH2 domain containing adapter protein F	0.0054	0.031	0.0466
Onchocerca volvulus	Neuropeptide F receptor homolog	0.0055	0.0348	0.0135
Echinococcus multilocularis	suppressor of cytokine signaling 6	0.0054	0.031	0.0466
Echinococcus granulosus	tyrosine protein kinase Src42A	0.0179	0.3813	0.5729
Brugia malayi	protein-tyrosine kinase	0.0053	0.0273	0.0365
Loa Loa (eye worm)	SH2 domain-containing protein	0.0054	0.031	0.031
Loa Loa (eye worm)	tubulin alpha 2	0.0139	0.2692	0.2692
Echinococcus granulosus	tubulin alpha 1C chain	0.0203	0.4494	0.6754
Onchocerca volvulus		0.0055	0.0348	0.0135
Trichomonas vaginalis	tubulin alpha-1 chain, putative	0.0119	0.2145	0.2596
Echinococcus granulosus	alpha 1A adrenergic receptor	0.0055	0.0348	0.0523
Loa Loa (eye worm)	follicle stimulating hormone receptor	0.0055	0.0348	0.0348
Loa Loa (eye worm)	hypothetical protein	0.0088	0.1262	0.1262
Echinococcus multilocularis	SH2 motif	0.0054	0.031	0.0466
Loa Loa (eye worm)	hypothetical protein	0.0251	0.5831	0.5831
Loa Loa (eye worm)	animal heme peroxidase	0.0251	0.5831	0.5831
Echinococcus granulosus	dro:myosuppressin receptor	0.0055	0.0348	0.0523
Onchocerca volvulus	Peroxidase homolog	0.0251	0.5831	1
Schistosoma mansoni	amine GPCR	0.0055	0.0348	0.0323
Schistosoma mansoni	tubulin subunit alpha	0.0203	0.4494	0.5944
Schistosoma mansoni	tensin-related	0.0054	0.031	0.0272
Brugia malayi	Tubulin beta-1 chain	0.0281	0.6655	0.889
Brugia malayi	Variant SH3 domain containing protein	0.0106	0.1781	0.2379
Loa Loa (eye worm)	TK/FER protein kinase	0.0069	0.0734	0.0734
Echinococcus granulosus	c src tyrosine kinase	0.0122	0.2205	0.3313
Echinococcus multilocularis	tyrosine protein kinase shark	0.0069	0.0734	0.1103
Schistosoma mansoni	proto-oncogene tyrosine-protein kinase src	0.0122	0.2205	0.284
Leishmania major	beta tubulin	0.0281	0.6655	1
Entamoeba histolytica	protein kinase, putative	0.0073	0.0834	0.0879
Trypanosoma cruzi	epsilon tubulin, putative	0.0148	0.2954	0.4201
Onchocerca volvulus	Peroxidasin homolog	0.0251	0.5831	1
Entamoeba histolytica	tubulin family protein	0.0281	0.6655	1
Schistosoma mansoni	alpha tubulin	0.0203	0.4494	0.5944
Giardia lamblia	Beta tubulin	0.0281	0.6655	1
Schistosoma mansoni	alpha tubulin	0.0203	0.4494	0.5944
Brugia malayi	Protein kinase domain containing protein	0.0069	0.0734	0.098
Trichomonas vaginalis	tubulin alpha-1 chain, putative	0.0203	0.4494	0.5853
Trypanosoma brucei	beta tubulin	0.0281	0.6655	1
Schistosoma mansoni	GTPase activating protein	0.0054	0.031	0.0272
Loa Loa (eye worm)	hypothetical protein	0.0055	0.0348	0.0348
Loa Loa (eye worm)	hypothetical protein	0.0055	0.0348	0.0348
Schistosoma mansoni	SH2A	0.0054	0.031	0.0272
Trichomonas vaginalis	tubulin beta chain, putative	0.0203	0.4494	0.5853
Leishmania major	alpha tubulin	0.0203	0.4494	0.6615
Leishmania major	alpha tubulin	0.0203	0.4494	0.6615
Trypanosoma cruzi	tubulin delta chain	0.0064	0.0605	0.052
Brugia malayi	putative neuropeptide receptor NPR1	0.0055	0.0348	0.0465
Toxoplasma gondii	hypothetical protein	0.04	1	1
Echinococcus multilocularis	tyrosine protein phosphatase non receptor type	0.0054	0.031	0.0466
Brugia malayi	RE15519p	0.0055	0.0348	0.0465
Schistosoma mansoni	neuropeptide f receptor 76f	0.0055	0.0348	0.0323
Echinococcus multilocularis	tm gpcr rhodopsin gpcr rhodopsin superfamily	0.0055	0.0348	0.0523
Echinococcus granulosus	g protein linked acetylcholine receptor gar 2a	0.0055	0.0348	0.0523
Loa Loa (eye worm)	hypothetical protein	0.0055	0.0348	0.0348
Echinococcus granulosus	neuropeptide FF receptor 2	0.0055	0.0348	0.0523
Leishmania major	beta tubulin	0.0281	0.6655	1
Echinococcus multilocularis	serotonin receptor	0.0055	0.0348	0.0523
Echinococcus multilocularis	suppressor of cytokine signaling 7	0.0054	0.031	0.0466
Echinococcus granulosus	tensin C1 domain containing phosphatase	0.0054	0.031	0.0466
Loa Loa (eye worm)	hypothetical protein	0.0119	0.2145	0.2145
Schistosoma mansoni	tubulin subunit beta	0.0281	0.6655	0.8873
Trypanosoma cruzi	zeta tubulin, putative	0.0064	0.0605	0.052
Echinococcus granulosus	suppressor of cytokine signaling 7	0.0054	0.031	0.0466
Leishmania major	alpha tubulin	0.0203	0.4494	0.6615
Loa Loa (eye worm)	G-protein-linked acetylcholine receptor protein 2	0.0055	0.0348	0.0348
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0055	0.0348	0.0523
Echinococcus granulosus	phosphatidylinositol 3 kinase regulatory subunit	0.0054	0.031	0.0466
Schistosoma mansoni	Dab2-interacting protein-like	0.0053	0.0273	0.0221
Trypanosoma brucei	beta tubulin	0.0148	0.2954	0.4201
Leishmania major	zeta tubulin, putative	0.0064	0.0605	0.052
Brugia malayi	Variant SH3 domain containing protein	0.0054	0.031	0.0415
Loa Loa (eye worm)	hypothetical protein	0.0055	0.0348	0.0348
Echinococcus granulosus	neuropeptide receptor	0.0055	0.0348	0.0523
Loa Loa (eye worm)	tubulin alpha chain	0.0203	0.4494	0.4494
Entamoeba histolytica	SH2 domain containing protein	0.0054	0.031	0.0059
Brugia malayi	hypothetical protein	0.0055	0.0348	0.0465
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0055	0.0348	0.0523
Loa Loa (eye worm)	alpha-tubulin	0.0203	0.4494	0.4494
Brugia malayi	tubulin alpha-2 chain	0.0203	0.4494	0.6004
Echinococcus multilocularis	tachykinin peptides receptor 99D	0.0055	0.0348	0.0523
Schistosoma mansoni	tubulin subunit epsilon	0.0148	0.2954	0.3856
Echinococcus multilocularis	SHC transforming protein 3	0.0054	0.031	0.0466
Loa Loa (eye worm)	hypothetical protein	0.0055	0.0348	0.0348
Brugia malayi	Variant SH3 domain containing protein	0.0053	0.0273	0.0365
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0055	0.0348	0.0523
Onchocerca volvulus	Dual oxidase homolog	0.0251	0.5831	1
Echinococcus granulosus	tm gpcr rhodopsin	0.0055	0.0348	0.0523
Trichomonas vaginalis	tubulin, putative	0.0084	0.1151	0.1218
Onchocerca volvulus		0.0055	0.0348	0.0135
Loa Loa (eye worm)	tubulin beta-4 chain	0.0281	0.6655	0.6655
Echinococcus multilocularis	tyrosine protein kinase Fps85D	0.0069	0.0734	0.1103
Giardia lamblia	Gamma tubulin	0.0148	0.2954	0.3883
Trichomonas vaginalis	tubulin gamma chain, putative	0.0281	0.6655	0.8848
Loa Loa (eye worm)	hypothetical protein	0.0203	0.4494	0.4494
Echinococcus granulosus	tyrosine protein kinase HCK	0.0073	0.0834	0.1253
Brugia malayi	Tubulin beta chain	0.0064	0.0605	0.0808
Schistosoma mansoni	neuropeptide F-like receptor	0.0055	0.0348	0.0323
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0055	0.0348	0.0523
Echinococcus granulosus	Tubulin beta 2C chain	0.0281	0.6655	1
Echinococcus multilocularis	G-protein coupled receptor, putative	0.0055	0.0348	0.0523
Echinococcus multilocularis	neuropeptide Y receptor	0.0055	0.0348	0.0523
Echinococcus multilocularis	sex peptide receptor	0.0055	0.0348	0.0523
Leishmania major	beta tubulin	0.0281	0.6655	1
Brugia malayi	AKH receptor	0.0055	0.0348	0.0465
Echinococcus multilocularis	g-protein coupled receptor	0.0055	0.0348	0.0523
Echinococcus granulosus	neuropeptides capa receptor	0.0055	0.0348	0.0523
Leishmania major	alpha tubulin	0.0203	0.4494	0.6615
Trichomonas vaginalis	tubulin epsilon chain, putative	0.0064	0.0605	0.046
Schistosoma mansoni	hypothetical protein	0.0055	0.0348	0.0323
Echinococcus granulosus	neuropeptide receptor A26	0.0055	0.0348	0.0523
Echinococcus granulosus	neuropeptide Y receptor	0.0055	0.0348	0.0523
Brugia malayi	SH2 domain containing protein	0.0054	0.031	0.0415
Echinococcus granulosus	expressed protein	0.0053	0.0273	0.041
Entamoeba histolytica	tubulin alpha chain, putative	0.0203	0.4494	0.6615
Loa Loa (eye worm)	hypothetical protein	0.0054	0.031	0.031
Schistosoma mansoni	neuropeptide receptor	0.0055	0.0348	0.0323
Echinococcus granulosus	tubulin epsilon chain	0.0148	0.2954	0.4439
Echinococcus multilocularis	expressed protein	0.0053	0.0273	0.041
Onchocerca volvulus		0.0069	0.0734	0.0829
Schistosoma mansoni	tubulin subunit alpha	0.0203	0.4494	0.5944
Brugia malayi	cytokine inducible SH2-containing protein 5	0.0054	0.031	0.0415
Loa Loa (eye worm)	TK/FER protein kinase	0.0069	0.0734	0.0734
Schistosoma mansoni	thyrotropin-releasing hormone receptor	0.0055	0.0348	0.0323
Schistosoma mansoni	amine GPCR	0.0055	0.0348	0.0323
Loa Loa (eye worm)	hypothetical protein	0.0054	0.031	0.031
Loa Loa (eye worm)	TK/FER protein kinase	0.0069	0.0734	0.0734
Schistosoma mansoni	tubulin subunit beta	0.0281	0.6655	0.8873
Brugia malayi	Tensin	0.0054	0.031	0.0415
Loa Loa (eye worm)	TK/FER protein kinase	0.0069	0.0734	0.0734
Echinococcus granulosus	tyrosine protein kinase Blk	0.0127	0.2342	0.3519
Leishmania major	alpha tubulin	0.0203	0.4494	0.6615
Brugia malayi	Dopamine receptor	0.0055	0.0348	0.0465
Echinococcus granulosus	sex peptide receptor	0.0055	0.0348	0.0523
Schistosoma mansoni	glutaminase	0.031	0.7486	1
Brugia malayi	tRNA modification GTPase TrmE family protein	0.0054	0.031	0.0415
Onchocerca volvulus		0.0055	0.0348	0.0135
Trypanosoma brucei	beta tubulin	0.0281	0.6655	1
Echinococcus multilocularis	neuropeptide receptor	0.0055	0.0348	0.0523
Mycobacterium tuberculosis	Cell division protein FtsZ	0.0064	0.0605	0.5
Leishmania major	epsilon tubulin, putative	0.0148	0.2954	0.4201
Loa Loa (eye worm)	hypothetical protein	0.0054	0.031	0.031
Onchocerca volvulus		0.0054	0.031	0.0067
Onchocerca volvulus	Suppressor of cytokine signaling at 36E homolog	0.0054	0.031	0.0067
Brugia malayi	SH2 domain containing protein	0.0069	0.0734	0.098
Echinococcus multilocularis	allatostatin A receptor	0.0055	0.0348	0.0523
Brugia malayi	Sex muscle abnormal protein 5	0.0106	0.1781	0.2379
Loa Loa (eye worm)	hypothetical protein	0.0055	0.0348	0.0348
Loa Loa (eye worm)	animal heme peroxidase	0.0251	0.5831	0.5831
Echinococcus multilocularis	serotonin receptor	0.0055	0.0348	0.0523
Leishmania major	beta tubulin	0.0281	0.6655	1
Echinococcus granulosus	tyrosine protein kinase Fps85D	0.0069	0.0734	0.1103
Echinococcus multilocularis	beta tubulin	0.0281	0.6655	1
Echinococcus granulosus	pyroglutamylated rfamide peptide receptor	0.0055	0.0348	0.0523
Echinococcus granulosus	peptide allatostatin:somatostatin	0.0055	0.0348	0.0523
Echinococcus multilocularis	breast cancer anti estrogen resistance protein	0.0053	0.0273	0.041
Schistosoma mansoni	neuropeptide receptor	0.0055	0.0348	0.0323
Trypanosoma brucei	alpha tubulin	0.0203	0.4494	0.6615
Loa Loa (eye worm)	neuropeptide F receptor	0.0055	0.0348	0.0348
Schistosoma mansoni	tyrosine-protein kinase zap-70	0.0054	0.031	0.0272
Schistosoma mansoni	tubulin subunit alpha	0.0064	0.0605	0.0671
Echinococcus multilocularis	tubulin epsilon chain	0.0148	0.2954	0.4439
Loa Loa (eye worm)	hypothetical protein	0.0054	0.031	0.031
Echinococcus granulosus	Tubulin alpha 1 chain	0.0203	0.4494	0.6754
Schistosoma mansoni	peroxidasin	0.0251	0.5831	0.7756
Echinococcus granulosus	tubulin alpha chain	0.0203	0.4494	0.6754
Loa Loa (eye worm)	hypothetical protein	0.0055	0.0348	0.0348
Loa Loa (eye worm)	hypothetical protein	0.0053	0.0273	0.0273
Echinococcus granulosus	rhodopsin orphan GPCR	0.0055	0.0348	0.0523
Echinococcus multilocularis	somatostatin receptor	0.0055	0.0348	0.0523
Loa Loa (eye worm)	hypothetical protein	0.0055	0.0348	0.0348
Loa Loa (eye worm)	hypothetical protein	0.009	0.1307	0.1307
Echinococcus multilocularis	nostrin	0.0053	0.0273	0.041
Trichomonas vaginalis	tubulin alpha chain, putative	0.0281	0.6655	0.8848
Trichomonas vaginalis	tubulin beta chain, putative	0.0203	0.4494	0.5853
Schistosoma mansoni	muscarinic acetylcholine (GAR) receptor	0.0055	0.0348	0.0323
Echinococcus granulosus	proto oncogene tyrosine protein kinase LCK	0.0179	0.3813	0.5729
Trichomonas vaginalis	tubulin, putative	0.0281	0.6655	0.8848
Echinococcus granulosus	tyrosine protein kinase ABL1	0.0069	0.0734	0.1103
Loa Loa (eye worm)	TK/ABL protein kinase	0.0069	0.0734	0.0734
Loa Loa (eye worm)	hypothetical protein	0.0055	0.0348	0.0348
Loa Loa (eye worm)	intermediate filament tail domain-containing protein	0.009	0.1307	0.1307
Loa Loa (eye worm)	hypothetical protein	0.0054	0.031	0.031
Echinococcus granulosus	tubulin delta chain	0.0064	0.0605	0.0909
Echinococcus multilocularis	tyrosine protein kinase HCK	0.0073	0.0834	0.1253
Loa Loa (eye worm)	animal heme peroxidase	0.0251	0.5831	0.5831
Onchocerca volvulus		0.0054	0.031	0.0067
Brugia malayi	Melatonin receptor type 1A	0.0055	0.0348	0.0465
Schistosoma mansoni	dynamin-associated protein	0.0053	0.0273	0.0221
Loa Loa (eye worm)	gonadotropin-releasing hormone receptor 2	0.0055	0.0348	0.0348
Loa Loa (eye worm)	hypothetical protein	0.0251	0.5831	0.5831
Wolbachia endosymbiont of Brugia malayi	cell division protein FtsZ	0.0064	0.0605	0.5
Brugia malayi	gonadotropin-releasing hormone receptor 2	0.0055	0.0348	0.0465
Trichomonas vaginalis	tubulin gamma chain, putative	0.0148	0.2954	0.3717
Loa Loa (eye worm)	hypothetical protein	0.0054	0.031	0.031
Schistosoma mansoni	lamin	0.009	0.1307	0.1623
Echinococcus granulosus	tyrosine protein phosphatase non receptor type	0.0054	0.031	0.0466
Brugia malayi	Protein-tyrosine phosphatase containing protein	0.0054	0.031	0.0415
Loa Loa (eye worm)	hypothetical protein	0.0069	0.0734	0.0734
Loa Loa (eye worm)	variant SH3 domain-containing protein	0.0054	0.031	0.031
Schistosoma mansoni	slit-robo rho gtpase activating protein	0.0053	0.0273	0.0221
Trichomonas vaginalis	tubulin alpha-1 chain, putative	0.0084	0.1151	0.1218
Plasmodium vivax	tubulin gamma chain, putative	0.0148	0.2954	0.3883
Brugia malayi	Serotonin receptor	0.0055	0.0348	0.0465
Onchocerca volvulus		0.0069	0.0734	0.0829
Schistosoma mansoni	histamine h1 receptor	0.0055	0.0348	0.0323
Echinococcus granulosus	g protein linked acetylcholine receptor gar 2a	0.0055	0.0348	0.0523
Loa Loa (eye worm)	hypothetical protein	0.0139	0.2692	0.2692
Brugia malayi	SH2 domain containing protein	0.0054	0.031	0.0415
Echinococcus multilocularis	tubulin gamma 1 chain	0.0148	0.2954	0.4439
Echinococcus multilocularis	Tubulin alpha 1 chain	0.0203	0.4494	0.6754
Loa Loa (eye worm)	5-hydroxytryptamine 2C receptor	0.0055	0.0348	0.0348
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0055	0.0348	0.0523
Entamoeba histolytica	protein kinase, putative	0.0054	0.031	0.0059
Loa Loa (eye worm)	hypothetical protein	0.0055	0.0348	0.0348
Onchocerca volvulus		0.0069	0.0734	0.0829
Leishmania major	alpha tubulin	0.0203	0.4494	0.6615
Echinococcus granulosus	tubulin subunit beta	0.0281	0.6655	1
Brugia malayi	hypothetical protein	0.0055	0.0348	0.0465
Leishmania major	beta tubulin	0.0281	0.6655	1
Leishmania major	beta tubulin	0.0281	0.6655	1
Trypanosoma brucei	epsilon tubulin	0.0148	0.2954	0.4201
Echinococcus granulosus	thyrotropin releasing hormone receptor	0.0055	0.0348	0.0523
Schistosoma mansoni	alpha tubulin	0.0203	0.4494	0.5944
Loa Loa (eye worm)	hypothetical protein	0.0055	0.0348	0.0348
Schistosoma mansoni	alpha-1 adrenergic receptor	0.0055	0.0348	0.0323
Onchocerca volvulus	Peroxidasin homolog	0.0251	0.5831	1
Echinococcus granulosus	tm gpcr rhodopsin	0.0055	0.0348	0.0523
Schistosoma mansoni	signal transducing adapter molecule (stam)	0.0053	0.0273	0.0221
Loa Loa (eye worm)	hypothetical protein	0.0055	0.0348	0.0348
Schistosoma mansoni	shc transforming protein	0.0054	0.031	0.0272
Loa Loa (eye worm)	alpha-tubulin	0.0203	0.4494	0.4494
Schistosoma mansoni	tubulin subunit beta	0.0281	0.6655	0.8873
Loa Loa (eye worm)	hypothetical protein	0.0055	0.0348	0.0348
Schistosoma mansoni	tubulin subunit beta	0.0281	0.6655	0.8873
Trichomonas vaginalis	tubulin beta-1 chain, putative	0.0064	0.0605	0.046
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0055	0.0348	0.0323
Brugia malayi	GnHR receptor homolog	0.0055	0.0348	0.0465
Trichomonas vaginalis	glutaminase, putative	0.031	0.7486	1
Schistosoma mansoni	chimerin-related rho-gtpase-activating protein	0.0054	0.031	0.0272
Loa Loa (eye worm)	hypothetical protein	0.0055	0.0348	0.0348
Brugia malayi	Fes/CIP4 homology domain containing protein	0.0053	0.0273	0.0365
Loa Loa (eye worm)	RhoGAP domain-containing protein	0.0054	0.031	0.031
Treponema pallidum	cell division protein FtsZ	0.0064	0.0605	0.5
Echinococcus granulosus	tyrosine protein kinase Srms	0.0069	0.0734	0.1103
Trypanosoma brucei	beta tubulin	0.0281	0.6655	1
Echinococcus multilocularis	hematopoietic lineage cell specific protein	0.0053	0.0273	0.041
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0055	0.0348	0.0323
Echinococcus multilocularis	c src tyrosine kinase	0.0122	0.2205	0.3313
Brugia malayi	Tubulin alpha chain	0.0203	0.4494	0.6004
Entamoeba histolytica	SH2-protein kinase domain containing protein	0.0054	0.031	0.0059
Echinococcus granulosus	epidermal growth factor receptor kinase	0.0053	0.0273	0.041
Echinococcus granulosus	growth factor receptor bound protein 2	0.0106	0.1781	0.2677
Loa Loa (eye worm)	hypothetical protein	0.0055	0.0348	0.0348
Echinococcus granulosus	SH2 motif	0.0054	0.031	0.0466
Echinococcus granulosus	growth hormone secretagogue receptor type 1	0.0055	0.0348	0.0523
Loa Loa (eye worm)	hypothetical protein	0.0055	0.0348	0.0348
Leishmania major	alpha tubulin	0.0203	0.4494	0.6615
Brugia malayi	sulfakinin receptor protein	0.0055	0.0348	0.0465
Loa Loa (eye worm)	SH2 domain-containing protein	0.0054	0.031	0.031
Brugia malayi	Peroxidasin	0.0251	0.5831	0.7789
Schistosoma mansoni	tyrosine kinase	0.0122	0.2205	0.284
Loa Loa (eye worm)	hypothetical protein	0.0055	0.0348	0.0348
Echinococcus multilocularis	signal transduction protein lnk realted	0.0054	0.031	0.0466
Loa Loa (eye worm)	hypothetical protein	0.0251	0.5831	0.5831
Echinococcus multilocularis	N chimaerin	0.0054	0.031	0.0466
Brugia malayi	SRC-1	0.0179	0.3813	0.5093
Schistosoma mansoni	peptide (FMRFamide/somatostatin)-like receptor	0.0055	0.0348	0.0323
Schistosoma mansoni	peptide (FMRFamide/somatostatin)-like receptor	0.0055	0.0348	0.0323
Loa Loa (eye worm)	hypothetical protein	0.0251	0.5831	0.5831
Echinococcus multilocularis	tyrosine protein kinase Src42A	0.0179	0.3813	0.5729
Loa Loa (eye worm)	melatonin receptor type 1A	0.0055	0.0348	0.0348
Loa Loa (eye worm)	hypothetical protein	0.0251	0.5831	0.5831
Trichomonas vaginalis	tubulin beta chain, putative	0.0203	0.4494	0.5853
Leishmania major	beta tubulin	0.0281	0.6655	1
Echinococcus granulosus	allatostatin A receptor	0.0055	0.0348	0.0523
Brugia malayi	Variant SH3 domain containing protein	0.0053	0.0273	0.0365
Loa Loa (eye worm)	hypothetical protein	0.0055	0.0348	0.0348
Loa Loa (eye worm)	hypothetical protein	0.0055	0.0348	0.0348
Schistosoma mansoni	hypothetical protein	0.0115	0.2009	0.2574
Plasmodium vivax	tubulin beta chain, putative	0.0281	0.6655	1
Plasmodium vivax	tubulin alpha chain, putative	0.0203	0.4494	0.6429
Echinococcus multilocularis	neuropeptides capa receptor	0.0055	0.0348	0.0523
Onchocerca volvulus		0.0055	0.0348	0.0135
Leishmania major	alpha tubulin	0.0203	0.4494	0.6615
Loa Loa (eye worm)	hypothetical protein	0.0251	0.5831	0.5831
Loa Loa (eye worm)	hypothetical protein	0.04	1	1
Loa Loa (eye worm)	tubulin alpha 2	0.0055	0.0343	0.0343
Loa Loa (eye worm)	hypothetical protein	0.0054	0.031	0.031
Loa Loa (eye worm)	hypothetical protein	0.0055	0.0348	0.0348
Schistosoma mansoni	biogenic amine (5HT) receptor	0.0055	0.0348	0.0323
Trichomonas vaginalis	conserved hypothetical protein	0.0064	0.0605	0.046
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0055	0.0348	0.0323
Echinococcus granulosus	7tm_1 domain containing protein	0.0055	0.0348	0.0523
Loa Loa (eye worm)	TK/FER protein kinase	0.0069	0.0734	0.0734
Echinococcus multilocularis	fmrfamide receptor	0.0055	0.0348	0.0523
Toxoplasma gondii	beta tubulin	0.0281	0.6655	0.6439
Brugia malayi	hypothetical protein	0.0055	0.0348	0.0465
Brugia malayi	Protein kinase domain containing protein	0.0069	0.0734	0.098
Echinococcus granulosus	tubulin beta 4A class IVa	0.0281	0.6655	1
Schistosoma mansoni	tyrosine kinase	0.0069	0.0734	0.0846
Echinococcus multilocularis	epidermal growth factor receptor kinase	0.0053	0.0273	0.041
Echinococcus granulosus	orexin receptor type 2	0.0055	0.0348	0.0523
Schistosoma mansoni	biogenic amine receptor	0.0055	0.0348	0.0323
Schistosoma mansoni	run and tbc1 domain containing	0.0053	0.0273	0.0221
Loa Loa (eye worm)	hypothetical protein	0.0053	0.0273	0.0273
Trypanosoma brucei	beta tubulin	0.0281	0.6655	1
Schistosoma mansoni	serine/threonine protein kinase	0.0068	0.0696	0.0795
Echinococcus granulosus	Tubulin beta 2C chain	0.0281	0.6655	1
Echinococcus multilocularis	transfer RNA-Ala	0.0053	0.0273	0.041
Schistosoma mansoni	development and differentiation-enhancing factor ddef	0.0053	0.0273	0.0221
Echinococcus multilocularis	musashi	0.009	0.1307	0.1965
Schistosoma mansoni	neuropeptide receptor	0.0055	0.0348	0.0323
Trypanosoma brucei	zeta tubulin	0.0064	0.0605	0.052
Brugia malayi	SH2 domain containing protein	0.0054	0.031	0.0415
Echinococcus granulosus	g protein coupled receptor	0.0055	0.0348	0.0523
Brugia malayi	SH2 domain containing protein	0.0054	0.031	0.0415
Echinococcus granulosus	tyrosine protein kinase Fyn	0.0179	0.3813	0.5729
Schistosoma mansoni	sorting nexin	0.0053	0.0273	0.0221
Loa Loa (eye worm)	hypothetical protein	0.0055	0.0348	0.0348
Loa Loa (eye worm)	hypothetical protein	0.0053	0.0273	0.0273
Echinococcus multilocularis	growth hormone secretagogue receptor type 1	0.0055	0.0348	0.0523
Trichomonas vaginalis	tubulin, putative	0.0064	0.0605	0.046
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0055	0.0348	0.0323
Echinococcus granulosus	expressed conserved protein	0.0054	0.031	0.0466
Echinococcus granulosus	guanine nucleotide exchange factor VAV2	0.0054	0.031	0.0466
Brugia malayi	SH2 domain containing protein	0.0069	0.0734	0.098
Loa Loa (eye worm)	hypothetical protein	0.0053	0.0273	0.0273
Echinococcus granulosus	rhodopsin orphan GPCR	0.0055	0.0348	0.0523
Schistosoma mansoni	suppressor of cytokine signaling	0.0054	0.031	0.0272
Onchocerca volvulus		0.0055	0.0348	0.0135
Echinococcus multilocularis	NCK adaptor protein	0.0106	0.1781	0.2677
Leishmania major	beta tubulin	0.0281	0.6655	1
Echinococcus multilocularis	Spectrin alpha actinin	0.0053	0.0273	0.041
Loa Loa (eye worm)	variant SH3 domain-containing protein	0.0053	0.0273	0.0273
Brugia malayi	Tubulin alpha-2 chain	0.0203	0.4494	0.6004
Brugia malayi	Serotonin receptor	0.0055	0.0348	0.0465
Echinococcus multilocularis		0.0054	0.031	0.0466
Brugia malayi	Animal haem peroxidase family protein	0.0251	0.5831	0.7789
Loa Loa (eye worm)	beta-tubulin	0.0281	0.6655	0.6655
Schistosoma mansoni	chimerin-related rho-gtpase-activating protein	0.0054	0.031	0.0272
Trichomonas vaginalis	tubulin epsilon chain, putative	0.0203	0.4494	0.5853
Echinococcus multilocularis	tm gpcr rhodopsin gpcr rhodopsin superfamily	0.0055	0.0348	0.0523
Giardia lamblia	Beta tubulin	0.0281	0.6655	1
Loa Loa (eye worm)	SH2 domain-containing protein	0.0054	0.031	0.031
Echinococcus granulosus	biogenic amine 5HT receptor	0.0055	0.0348	0.0523
Loa Loa (eye worm)	hypothetical protein	0.0251	0.5831	0.5831
Echinococcus granulosus	tachykinin peptides receptor 99D	0.0055	0.0348	0.0523
Trypanosoma brucei	tubulin delta chain	0.0064	0.0605	0.052
Echinococcus granulosus	Tubulin beta 2C chain	0.0281	0.6655	1
Trypanosoma cruzi	epsilon tubulin, putative	0.0148	0.2954	0.4201
Echinococcus multilocularis	neuropeptide Y receptor	0.0055	0.0348	0.0523
Echinococcus multilocularis	tm gpcr rhodopsin gpcr rhodopsin superfamily	0.0055	0.0348	0.0523
Giardia lamblia	Alpha-tubulin	0.0203	0.4494	0.6429
Loa Loa (eye worm)	tubulin alpha 2	0.0139	0.2692	0.2692
Echinococcus granulosus	tyrosine protein kinase Fyn	0.0179	0.3813	0.5729
Toxoplasma gondii	beta-tubulin, putative	0.0281	0.6655	0.6439
Trypanosoma brucei	zeta tubulin, putative	0.0064	0.0605	0.052
Loa Loa (eye worm)	TK/FER protein kinase	0.0069	0.0734	0.0734
Brugia malayi	larval opioid receptor	0.0055	0.0348	0.0465
Echinococcus multilocularis	hypothetical protein	0.0203	0.4494	0.6754
Loa Loa (eye worm)	G-protein coupled receptor	0.0055	0.0348	0.0348
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0055	0.0348	0.0323
Loa Loa (eye worm)	hypothetical protein	0.0251	0.5831	0.5831
Loa Loa (eye worm)	TK/FER protein kinase	0.0069	0.0734	0.0734
Brugia malayi	Variant SH3 domain containing protein	0.0053	0.0273	0.0365
Schistosoma mansoni	tubulin subunit gamma	0.0148	0.2954	0.3856
Brugia malayi	ORL1-like opioid receptor	0.0055	0.0348	0.0465
Schistosoma mansoni	C-fyn	0.0053	0.0273	0.0221
Loa Loa (eye worm)	hypothetical protein	0.0055	0.0348	0.0348
Schistosoma mansoni	growth factor receptor-bound protein	0.0106	0.1781	0.2266
Onchocerca volvulus		0.0055	0.0348	0.0135
Echinococcus multilocularis	dro:myosuppressin receptor	0.0055	0.0348	0.0523
Schistosoma mansoni	hypothetical protein	0.0053	0.0273	0.0221
Entamoeba histolytica	tubulin family protein	0.0281	0.6655	1
Loa Loa (eye worm)	hypothetical protein	0.0055	0.0348	0.0348
Loa Loa (eye worm)	hypothetical protein	0.0251	0.5831	0.5831
Schistosoma mansoni	hypothetical protein	0.0054	0.031	0.0272
Brugia malayi	Animal haem peroxidase family protein	0.0251	0.5831	0.7789
Loa Loa (eye worm)	hypothetical protein	0.0054	0.031	0.031
Trypanosoma brucei	epsilon tubulin	0.0148	0.2954	0.4201
Echinococcus granulosus	lamin dm0	0.009	0.1307	0.1965
Schistosoma mansoni	biogenic amine (5HT) receptor	0.0055	0.0348	0.0323
Brugia malayi	Cell division protein ftsZ	0.0064	0.0605	0.0808
Brugia malayi	Tubulin alpha-2 chain	0.0203	0.4494	0.6004
Loa Loa (eye worm)	inward rectifying k channel family protein 1	0.04	1	1
Schistosoma mansoni	peroxidasin	0.0251	0.5831	0.7756
Echinococcus granulosus	tubulin alpha	0.0148	0.2954	0.4439
Schistosoma mansoni	biogenic amine receptor	0.0055	0.0348	0.0323
Trichomonas vaginalis	tubulin alpha chain, putative	0.0084	0.1151	0.1218
Brugia malayi	STAT protein, DNA binding domain containing protein	0.0054	0.031	0.0415
Toxoplasma gondii	tubulin/FtsZ family, GTPase domain-containing protein	0.0148	0.2954	0.25
Loa Loa (eye worm)	hypothetical protein	0.0106	0.1781	0.1781
Echinococcus multilocularis	Tubulin alpha 1 chain	0.0203	0.4494	0.6754
Loa Loa (eye worm)	hypothetical protein	0.0054	0.031	0.031
Echinococcus multilocularis	tyrosine protein kinase Src42A	0.0111	0.1918	0.2883
Trichomonas vaginalis	tubulin beta chain, putative	0.0203	0.4494	0.5853
Echinococcus multilocularis	SH2 motif	0.0054	0.031	0.0466
Echinococcus multilocularis	lamin dm0	0.009	0.1307	0.1965
Leishmania major	beta tubulin	0.0281	0.6655	1
Echinococcus granulosus	intersectin 2	0.0053	0.0273	0.041
Plasmodium falciparum	alpha tubulin 1	0.0203	0.4494	0.6429
Schistosoma mansoni	signal transduction protein lnk-related	0.0054	0.031	0.0272
Loa Loa (eye worm)	glutaminase 2	0.031	0.7486	0.7486
Echinococcus multilocularis	tubulin, beta 4A class IVa	0.0281	0.6655	1
Brugia malayi	Spectrin alpha chain	0.0053	0.0273	0.0365
Echinococcus granulosus	tubulin alpha chain	0.0203	0.4494	0.6754
Trichomonas vaginalis	tubulin epsilon chain, putative	0.0281	0.6655	0.8848
Echinococcus granulosus	suppressor of cytokine signaling 6	0.0054	0.031	0.0466
Onchocerca volvulus	Suppressor of cytokine signaling 7 homolog	0.0054	0.031	0.0067
Echinococcus multilocularis	Tubulin beta 2C chain	0.0281	0.6655	1
Loa Loa (eye worm)	hypothetical protein	0.0053	0.0273	0.0273
Loa Loa (eye worm)	TYRA-2 protein	0.0055	0.0348	0.0348
Schistosoma mansoni	dreadlocks/dock	0.0053	0.0273	0.0221
Leishmania major	beta tubulin	0.0281	0.6655	1
Echinococcus multilocularis	SH2 motif	0.0054	0.031	0.0466
Trichomonas vaginalis	tubulin epsilon chain, putative	0.0203	0.4494	0.5853
Loa Loa (eye worm)	hypothetical protein	0.0055	0.0348	0.0348
Loa Loa (eye worm)	hypothetical protein	0.0055	0.0348	0.0348
Echinococcus granulosus	alpha tubulin	0.0203	0.4494	0.6754
Brugia malayi	beta-tubulin, identical	0.0281	0.6655	0.889
Echinococcus granulosus	SH2 motif	0.0054	0.031	0.0466
Loa Loa (eye worm)	hypothetical protein	0.0055	0.0348	0.0348
Trypanosoma cruzi	alpha tubulin, putative	0.0203	0.4494	0.6615
Loa Loa (eye worm)	hypothetical protein	0.0055	0.0348	0.0348
Onchocerca volvulus		0.0054	0.031	0.0067
Onchocerca volvulus		0.0055	0.0348	0.0135
Schistosoma mansoni	tensin-related	0.0054	0.031	0.0272
Loa Loa (eye worm)	hypothetical protein	0.0055	0.0348	0.0348
Loa Loa (eye worm)	hypothetical protein	0.0054	0.031	0.031
Brugia malayi	Animal haem peroxidase family protein	0.0251	0.5831	0.7789
Echinococcus multilocularis	cytoplasmic intermediate filament protein	0.0043	0.0011	0.0017
Schistosoma mansoni	sh3-containing grb2-like protein 1 (endophilin II)	0.0053	0.0273	0.0221
Loa Loa (eye worm)	BEN-1 protein	0.0281	0.6655	0.6655
Leishmania major	beta tubulin	0.0281	0.6655	1
Echinococcus multilocularis	tyrosine protein kinase Fyn	0.0127	0.2342	0.3519
Echinococcus multilocularis	tubulin subunit beta	0.0281	0.6655	1
Echinococcus multilocularis	SH2 domain containing protein 7	0.0054	0.031	0.0466
Plasmodium vivax	tubulin alpha chain, putative	0.0203	0.4494	0.6429
Loa Loa (eye worm)	hypothetical protein	0.0043	0.0011	0.0011
Schistosoma mansoni	biogenic amine (dopamine) receptor	0.0055	0.0348	0.0323
Loa Loa (eye worm)	hypothetical protein	0.0055	0.0348	0.0348
Echinococcus granulosus	tyrosine protein kinase Lyn	0.0179	0.3813	0.5729
Echinococcus granulosus	tm gpcr rhodopsin	0.0055	0.0348	0.0523
Trichomonas vaginalis	tubulin beta chain, putative	0.0203	0.4494	0.5853
Loa Loa (eye worm)	hypothetical protein	0.04	1	1
Trichomonas vaginalis	tubulin beta chain, putative	0.0084	0.1151	0.1218
Onchocerca volvulus		0.0055	0.0348	0.0135
Loa Loa (eye worm)	hypothetical protein	0.0055	0.0348	0.0348
Leishmania major	alpha tubulin	0.0203	0.4494	0.6615
Echinococcus granulosus	endophilin A3	0.0053	0.0273	0.041
Echinococcus multilocularis	G protein coupled 5 hydroxytryptamine receptor	0.0055	0.0348	0.0523
Echinococcus granulosus	peroxidasin	0.0251	0.5831	0.8762
Schistosoma mansoni	tubulin subunit delta	0.0064	0.0605	0.0671
Brugia malayi	putative neuropeptide receptor	0.0055	0.0348	0.0465
Echinococcus multilocularis	tubulin delta chain	0.0064	0.0605	0.0909
Schistosoma mansoni	amine GPCR	0.0055	0.0348	0.0323
Echinococcus granulosus	tyrosine protein kinase Src42A	0.0111	0.1918	0.2883
Giardia lamblia	Alpha-tubulin	0.0203	0.4494	0.6429
Onchocerca volvulus	Chorion peroxidase homolog	0.0251	0.5831	1
Brugia malayi	Intermediate filament tail domain containing protein	0.009	0.1307	0.1746
Echinococcus granulosus	hypothetical protein	0.0055	0.0348	0.0523
Trypanosoma brucei	tubulin gamma chain	0.0148	0.2954	0.4201
Echinococcus multilocularis	tyrosine protein kinase Fyn	0.0179	0.3813	0.5729
Echinococcus granulosus	hypothetical protein	0.0054	0.031	0.0466
Onchocerca volvulus		0.0055	0.0348	0.0135
Onchocerca volvulus		0.0055	0.0348	0.0135
Echinococcus multilocularis	Tubulin beta 2C chain	0.0281	0.6655	1
Echinococcus granulosus	Tubulin beta 2C chain	0.0281	0.6655	1
Echinococcus granulosus	src region	0.0053	0.0273	0.041
Echinococcus granulosus	tyrosine protein kinase shark	0.0069	0.0734	0.1103
Trichomonas vaginalis	tubulin alpha-1 chain, putative	0.0139	0.2692	0.3353
Brugia malayi	Animal haem peroxidase family protein	0.0251	0.5831	0.7789
Onchocerca volvulus		0.0054	0.031	0.0067
Echinococcus granulosus	signal transduction protein lnk realted	0.0054	0.031	0.0466
Leishmania major	beta tubulin	0.0281	0.6655	1
Trypanosoma brucei	epsilon tubulin	0.0148	0.2954	0.4201
Loa Loa (eye worm)	thyroid receptor interactor	0.0053	0.0273	0.0273
Echinococcus granulosus	slit robo rho gtpase activating protein 1	0.0053	0.0273	0.041
Echinococcus granulosus	tubulin gamma 1 chain	0.0148	0.2954	0.4439
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0055	0.0348	0.0323
Echinococcus multilocularis	biogenic amine (5HT) receptor	0.0055	0.0348	0.0523
Loa Loa (eye worm)	hypothetical protein	0.0055	0.0348	0.0348
Onchocerca volvulus		0.009	0.1307	0.1861
Onchocerca volvulus		0.0055	0.0348	0.0135
Loa Loa (eye worm)	hypothetical protein	0.0251	0.5831	0.5831
Echinococcus granulosus	G protein coupled receptor 139	0.0055	0.0348	0.0523
Brugia malayi	G protein-coupled receptor F59B2.13	0.0055	0.0348	0.0465
Trypanosoma brucei	alpha tubulin, putative	0.0084	0.1151	0.1376
Echinococcus multilocularis	tyrosine protein kinase ABL1	0.0069	0.0734	0.1103
Loa Loa (eye worm)	neuropeptide F receptor	0.0055	0.0348	0.0348
Schistosoma mansoni	tubulin subunit beta	0.0281	0.6655	0.8873
Onchocerca volvulus		0.0084	0.1151	0.158
Echinococcus multilocularis	tyrosine protein kinase Abl	0.0122	0.2205	0.3313
Echinococcus multilocularis	tubulin beta 1 chain	0.0281	0.6655	1
Brugia malayi	Tachykinin-like peptides receptor 99D	0.0055	0.0348	0.0465
Trypanosoma cruzi	tubulin delta chain	0.0064	0.0605	0.052
Brugia malayi	G protein-coupled receptor	0.0055	0.0348	0.0465
Trypanosoma brucei	alpha tubulin	0.0203	0.4494	0.6615
Echinococcus multilocularis	peroxidasin	0.0251	0.5831	0.8762
Echinococcus multilocularis	tubulin alpha 3 chain	0.0203	0.4494	0.6754
Echinococcus multilocularis	tyrosine protein kinase Fyn	0.0179	0.3813	0.5729
Loa Loa (eye worm)	hypothetical protein	0.0054	0.031	0.031
Loa Loa (eye worm)	hypothetical protein	0.0055	0.0348	0.0348
Echinococcus multilocularis	pyroglutamylated rfamide peptide receptor	0.0055	0.0348	0.0523
Loa Loa (eye worm)	hypothetical protein	0.0251	0.5831	0.5831
Schistosoma mansoni	growth factor receptor-bound protein	0.0106	0.1781	0.2266
Echinococcus multilocularis	neuropeptide FF receptor 2	0.0055	0.0348	0.0523
Brugia malayi	follicle stimulating hormone receptor	0.0055	0.0348	0.0465
Loa Loa (eye worm)	tubulin alpha-3 chain	0.0119	0.2145	0.2145
Echinococcus granulosus	tubulin alpha chain	0.0203	0.4494	0.6754
Loa Loa (eye worm)	tubulin alpha chain	0.0203	0.4494	0.4494
Plasmodium falciparum	tubulin beta chain	0.0281	0.6655	1
Echinococcus granulosus	g protein coupled receptor	0.0055	0.0348	0.0523
Brugia malayi	alpha-tubulin	0.0203	0.4494	0.6004
Onchocerca volvulus	Dopamine\/Ecdysteroid receptor homolog	0.0055	0.0348	0.0135
Brugia malayi	glutaminase DH11.1	0.031	0.7486	1
Brugia malayi	hypothetical protein	0.0055	0.0348	0.0465
Brugia malayi	Src substrate cortactin	0.0053	0.0273	0.0365
Brugia malayi	hypothetical protein	0.0055	0.0348	0.0465
Echinococcus multilocularis	tyrosine protein kinase Blk	0.0127	0.2342	0.3519
Echinococcus granulosus	tyrosine protein kinase Btk29A	0.0122	0.2205	0.3313
Echinococcus multilocularis	g protein coupled receptor	0.0055	0.0348	0.0523
Loa Loa (eye worm)	hypothetical protein	0.0055	0.0348	0.0348
Loa Loa (eye worm)	animal heme peroxidase	0.0251	0.5831	0.5831
Echinococcus multilocularis	tyrosine protein kinase Src64B	0.0179	0.3813	0.5729
Brugia malayi	Myosin tail family protein	0.0053	0.0273	0.0365
Echinococcus multilocularis	tubulin alpha 3 chain	0.0203	0.4494	0.6754
Brugia malayi	hypothetical protein	0.0055	0.0348	0.0465
Brugia malayi	Unidentified vitellogenin-linked transcript protein 6, putative	0.0055	0.0348	0.0465
Loa Loa (eye worm)	tubulin beta-1 chain	0.0281	0.6655	0.6655
Loa Loa (eye worm)	blistered cuticle protein 3	0.0251	0.5831	0.5831
Echinococcus multilocularis	g protein linked acetylcholine receptor gar 2a	0.0055	0.0348	0.0523
Echinococcus multilocularis	orexin receptor type 2	0.0055	0.0348	0.0523
Onchocerca volvulus		0.0069	0.0734	0.0829
Echinococcus multilocularis	fmrfamide receptor	0.0055	0.0348	0.0523
Echinococcus granulosus	peroxisome assembly protein 26	0.0203	0.4494	0.6754
Echinococcus multilocularis	beta tubulin	0.0281	0.6655	1
Echinococcus granulosus	nostrin	0.0053	0.0273	0.041
Onchocerca volvulus		0.0251	0.5831	1
Entamoeba histolytica	tubulin gamma chain	0.0148	0.2954	0.4201
Schistosoma mansoni	peptide (allatostatin)-like receptor	0.0055	0.0348	0.0323
Echinococcus multilocularis	proto oncogene tyrosine protein kinase LCK	0.0179	0.3813	0.5729
Schistosoma mansoni	tensin	0.0054	0.031	0.0272
Brugia malayi	hypothetical protein	0.0055	0.0348	0.0465
Schistosoma mansoni	hypothetical protein	0.0053	0.0273	0.0221
Echinococcus granulosus	beta tubulin	0.0281	0.6655	1
Echinococcus multilocularis	tyrosine protein phosphatase non receptor type	0.0054	0.031	0.0466
Brugia malayi	Protein kinase domain containing protein	0.0069	0.0734	0.098
Echinococcus granulosus	neuropeptide s receptor	0.0055	0.0348	0.0523
Leishmania major	beta tubulin	0.0281	0.6655	1
Brugia malayi	Dopamine receptor protein 1	0.0055	0.0348	0.0465
Trichomonas vaginalis	tubulin beta chain, putative	0.0203	0.4494	0.5853
Schistosoma mansoni	tyrosine kinase	0.0179	0.3813	0.502
Schistosoma mansoni	cell polarity protein	0.0053	0.0273	0.0221
Schistosoma mansoni	peptide (FMRFamide/neurokinin-3)-like receptor	0.0055	0.0348	0.0323
Trypanosoma cruzi	zeta tubulin, putative	0.0064	0.0605	0.052
Echinococcus granulosus	Tubulin alpha 1 chain	0.0203	0.4494	0.6754
Schistosoma mansoni	hypothetical protein	0.0055	0.0348	0.0323
Loa Loa (eye worm)	TK protein kinase	0.0073	0.0834	0.0834
Leishmania major	beta tubulin	0.0281	0.6655	1
Brugia malayi	G-protein coupled receptor	0.0055	0.0348	0.0465
Loa Loa (eye worm)	cytoplasmic intermediate filament protein	0.0048	0.0144	0.0144

Activities

Activity type	Activity value	Assay description	Source	Reference
Average weight (functional)	= 24 g mouse-1	Antitumor activity against L1210 leukemia in mice (Average weight per mouse on day 1.) at the dose of 113 mg/kg	ChEMBL.	7057424
Average weight (functional)	= 24 g mouse-1	Antitumor activity against L1210 leukemia in mice (Average weight per mouse on day 1.) at the dose of 267 mg/kg	ChEMBL.	7057424
Average weight (functional)	= 24.4 g mouse-1	Antitumor activity against L1210 leukemia in mice (Average weight per mouse on day 1.) at the dose of 200 mg/kg	ChEMBL.	7057424
ILS (functional)	= 112 %	Antitumor activity against L1210 leukemia in mice (Percent increase in life span.) at the dose of 113 mg/kg	ChEMBL.	7057424
ILS (functional)	= 137 %	Antitumor activity against L1210 leukemia in mice (Percent increase in life span.) at the dose of 200 mg/kg (mice surviving 20 or more days)	ChEMBL.	7057424
ILS (functional)	= 150 %	Antitumor activity against L1210 leukemia in mice (Percent increase in life span.) at the dose of 267 mg/kg (mice surviving 20 or more days)	ChEMBL.	7057424
T/C (functional)	= 0 day	Antitumor activity against L1210 leukemia in mice (median survival) at the dose of 113 mg/kg; Value represented as Test/Control = 17/8	ChEMBL.	7057424
T/C (functional)	= 0 day	Antitumor activity against L1210 leukemia in mice (median survival) at the dose of 200 mg/kg; Value represented as Test/Control = 19/8	ChEMBL.	7057424
T/C (functional)	= 0 day	Antitumor activity against L1210 leukemia in mice (median survival) at the dose of 267 mg/kg; Value represented as Test/Control = 20/8	ChEMBL.	7057424
Weight change (functional)	= -16 %	Antitumor activity against L1210 leukemia in mice (Average 7-day weight change (%)) at the dose of 200 mg/kg	ChEMBL.	7057424
Weight change (functional)	= -16 %	Antitumor activity against L1210 leukemia in mice (Average 7-day weight change (%)) at the dose of 267 mg/kg	ChEMBL.	7057424
Weight change (functional)	= -11 %	Antitumor activity against L1210 leukemia in mice (Average 7-day weight change (%)) at the dose of 113 mg/kg	ChEMBL.	7057424
Weight change (functional)	= -4 g mouse-1	Antitumor activity against L1210 leukemia in mice (Average 7-day weight change) at the dose of 200 mg/kg	ChEMBL.	7057424
Weight change (functional)	= -3.6 g mouse-1	Antitumor activity against L1210 leukemia in mice (Average 7-day weight change) at the dose of 267 mg/kg	ChEMBL.	7057424
Weight change (functional)	= -2.6 g mouse-1	Antitumor activity against L1210 leukemia in mice (Average 7-day weight change) at the dose of 113 mg/kg	ChEMBL.	7057424

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

ChEMBL: 176817

Bibliographic References

1 literature reference was collected for this gene.

If you have references for this compound, please enter them in a user comment (below) or Contact us.

Detailed information for compound 73608