TDR Targets

Basic information

Technical information

TDR Targets ID: 736767
Name: 1-(3-chlorophenyl)-4-[(3-methylphenyl)methyl] piperazine
MW: 300.826 | Formula: C18H21ClN2
H donors: 0 H acceptors: 0 LogP: 4.34 Rotable bonds: 3
Rule of 5 violations (Lipinski): 1
SMILES: Cc1cccc(c1)CN1CCN(CC1)c1cccc(c1)Cl
InChi: 1S/C18H21ClN2/c1-15-4-2-5-16(12-15)14-20-8-10-21(11-9-20)18-7-3-6-17(19)13-18/h2-7,12-13H,8-11,14H2,1H3
InChiKey: DGKUBJRVFFPESP-UHFFFAOYSA-N

Network

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Target Layer

Model Organisms

Species	Viewmode
Arabidopsis thaliana
Caenorhabditis elegans
Dictyostelium discoideum
Drosophila melanogaster
Escherichia coli
Homo sapiens
Mus musculus
Oryza sativa
Saccharomyces cerevisiae
Schmidtea mediterranea
Other organisms

TDR Pathogens:

Species	Viewmode
Brugia malayi
Chlamydia trachomatis
Echinococcus granulosus
Entamoeba histolytica
Echinococcus multilocularis
Giardia lamblia
Leishmania major
Loa Loa (eye worm)
Mycobacterium leprae
Mycobacterium tuberculosis
Mycobacterium ulcerans
Onchocerca volvulus
Plasmodium falciparum
Plasmodium vivax
Schistosoma mansoni
Trypanosoma brucei
Trypanosoma cruzi
Toxoplasma gondii
Treponema pallidum
Trichomonas vaginalis
Wolbachia endosymbiont of Brugia malayi

Other Pathogens:

Species	Viewmode
Babesia bovis
Candida albicans
Cryptosporidium hominis
Cryptosporidium parvum
Leishmania braziliensis
Leishmania donovani
Leishmania infantum
Leishmania mexicana
Neospora caninum
Plasmodium berghei
Plasmodium knowlesi
Plasmodium yoelii
Schistosoma japonicum
Trypanosoma brucei gambiense
Trypanosoma congolense
Theileria parva

Compound Layer

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Clustering layers

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Synonyms

1-(3-chlorophenyl)-4-(3-methylbenzyl)piperazine
Oprea1_426734

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology

No druggable targets predicted by orthology data

By sequence similarity to non orthologous known druggable targets

No druggable targets predicted by sequence similarity

Ranking Plot

Putative Targets List

Species	Potential target	Raw	Global	Species
Brugia malayi	Pre-SET motif family protein	0.0031	0.0844	0.0866
Echinococcus granulosus	General substrate transporter	0.0098	0.365	0.3744
Echinococcus multilocularis	COUP TF:Svp nuclear hormone receptor	0.0021	0.0425	0.0436
Echinococcus granulosus	solute carrier family 22	0.0016	0.0199	0.0204
Echinococcus granulosus	synaptic vesicle 2 protein	0.0016	0.0199	0.0204
Echinococcus multilocularis	Nuclear hormone receptor family member nhr 41	0.0021	0.0425	0.0436
Echinococcus granulosus	solute carrier family 22	0.0016	0.0199	0.0204
Echinococcus granulosus	histone acetyltransferase KAT2B	0.0043	0.134	0.1375
Echinococcus granulosus	Basic leucine zipper bZIP transcription	0.0077	0.2769	0.2841
Echinococcus granulosus	COUP TF:Svp nuclear hormone receptor	0.0021	0.0425	0.0436
Trichomonas vaginalis	glucose transporter, putative	0.0035	0.1013	0.083
Schistosoma mansoni	nuclear receptor 2DBD-gamma	0.0021	0.0425	0.0746
Loa Loa (eye worm)	GTP-binding regulatory protein Gs alpha-S chain	0.0047	0.1501	0.154
Leishmania major	glucose transporter/membrane transporter D2, putative	0.0035	0.1013	1
Schistosoma mansoni	glucose transport protein	0.0114	0.4325	0.7588
Brugia malayi	Ligand-binding domain of nuclear hormone receptor family protein	0.0021	0.0425	0.0436
Loa Loa (eye worm)	hypothetical protein	0.0021	0.0425	0.0436
Mycobacterium ulcerans	fusion protein of transposase for IS2606 and sialic acid-transport integral membrane protein NanT	0.0016	0.0199	0.5
Schistosoma mansoni	Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein)	0.0047	0.1501	0.2634
Trypanosoma cruzi	hexose transporter, putative	0.0019	0.0338	0.1706
Echinococcus multilocularis	survival motor neuron protein 1	0.0243	0.9748	1
Brugia malayi	Nuclear hormone receptor-like 1	0.0021	0.0425	0.0436
Loa Loa (eye worm)	nuclear hormone receptor family member nhr-1	0.0021	0.0425	0.0436
Loa Loa (eye worm)	hypothetical protein	0.0016	0.0199	0.0204
Loa Loa (eye worm)	acetyltransferase	0.0147	0.57	0.5847
Echinococcus multilocularis	Sugar transporter ERD6 protein	0.0016	0.0199	0.0204
Loa Loa (eye worm)	hypothetical protein	0.0016	0.0199	0.0204
Echinococcus granulosus	solute carrier family 22	0.0016	0.0199	0.0204
Loa Loa (eye worm)	hypothetical protein	0.0016	0.0199	0.0204
Trypanosoma brucei	glucose transporter, putative	0.0035	0.1013	1
Plasmodium vivax	hexose transporter	0.0114	0.4325	1
Entamoeba histolytica	hypothetical protein	0.0077	0.2769	1
Brugia malayi	Nuclear hormone receptor family member nhr-19	0.0021	0.0425	0.0436
Trichomonas vaginalis	conserved hypothetical protein	0.0035	0.1013	0.083
Echinococcus multilocularis	histone lysine N methyltransferase SETMAR	0.0031	0.0844	0.0866
Brugia malayi	GTP-binding regulatory protein Gs alpha-S chain, putative	0.0047	0.1501	0.154
Trypanosoma brucei	glucose transporter 2A	0.0035	0.1013	1
Brugia malayi	Nuclear hormone receptor family member nhr-1	0.0021	0.0425	0.0436
Echinococcus multilocularis	solute carrier family 22	0.0016	0.0199	0.0204
Loa Loa (eye worm)	hypothetical protein	0.0021	0.0425	0.0436
Trypanosoma brucei	glucose transporter, putative	0.0035	0.1013	1
Brugia malayi	nuclear hormone receptor	0.0021	0.0425	0.0436
Leishmania major	glucose transporter, lmgt1	0.0035	0.1013	1
Echinococcus granulosus	nuclear receptor 2DBD gamma	0.0021	0.0425	0.0436
Brugia malayi	Ligand-binding domain of nuclear hormone receptor family protein	0.0021	0.0425	0.0436
Schistosoma mansoni	nuclear transcription factor X-box binding 1 (nfx1)	0.0016	0.0199	0.0349
Echinococcus granulosus	solute carrier family 2 facilitated glucose	0.0114	0.4325	0.4437
Trichomonas vaginalis	sugar transporter, putative	0.0035	0.1013	0.083
Plasmodium vivax	histone acetyltransferase GCN5, putative	0.0043	0.134	0.2766
Echinococcus multilocularis	nuclear receptor 2DBD gamma	0.0021	0.0425	0.0436
Schistosoma mansoni	steroid hormone receptor ad4bp	0.0021	0.0425	0.0746
Mycobacterium tuberculosis	Probable conserved integral membrane transport protein	0.0016	0.0199	0.5
Brugia malayi	Nuclear hormone receptor family member nhr-3	0.0021	0.0425	0.0436
Loa Loa (eye worm)	hypothetical protein	0.0016	0.0199	0.0204
Echinococcus granulosus	5'partial\|histone lysine N methyltransferase SETDB2	0.003	0.0795	0.0816
Loa Loa (eye worm)	hypothetical protein	0.0016	0.0199	0.0204
Loa Loa (eye worm)	major facilitator superfamily transporter	0.0016	0.0199	0.0204
Echinococcus granulosus	solute carrier family 2 facilitated glucose	0.0114	0.4325	0.4437
Brugia malayi	Nuclear hormone receptor family member nhr-25	0.0021	0.0425	0.0436
Brugia malayi	Nuclear hormone receptor family member nhr-14	0.0021	0.0425	0.0436
Echinococcus granulosus	Sugar transporter ERD6 protein	0.0016	0.0199	0.0204
Schistosoma mansoni	histone-lysine n-methyltransferase setb1	0.0031	0.0844	0.1481
Schistosoma mansoni	sugar transporter	0.0016	0.0199	0.0349
Plasmodium vivax	SET domain protein, putative	0.0031	0.0844	0.1563
Brugia malayi	photoreceptor-specific nuclear receptor	0.0021	0.0425	0.0436
Loa Loa (eye worm)	hypothetical protein	0.0243	0.9748	1
Giardia lamblia	Histone acetyltransferase GCN5	0.004	0.1189	1
Schistosoma mansoni	RAR-like nuclear receptor	0.0021	0.0425	0.0746
Brugia malayi	Sugar transporter family protein	0.0114	0.4325	0.4437
Trypanosoma brucei	glucose transporter, putative	0.0035	0.1013	1
Onchocerca volvulus		0.0021	0.0425	0.0231
Echinococcus granulosus	histone acetyltransferase KAT2B	0.0143	0.5527	0.567
Echinococcus multilocularis	FTZ F1 nuclear receptor protein	0.0021	0.0425	0.0436
Brugia malayi	Sugar transporter family protein	0.0016	0.0199	0.0204
Brugia malayi	major facilitator superfamily protein	0.0016	0.0199	0.0204
Echinococcus multilocularis	solute carrier family 22	0.0016	0.0199	0.0204
Brugia malayi	Iron-sulfur cluster assembly accessory protein	0.005	0.1609	0.1651
Schistosoma mansoni	retinoid-x-receptor (RXR)	0.0021	0.0425	0.0746
Loa Loa (eye worm)	sugar transporter	0.0114	0.4325	0.4437
Echinococcus multilocularis	solute carrier family 2 facilitated glucose	0.0114	0.4325	0.4437
Echinococcus granulosus	hepatocyte nuclear factor 4 alpha	0.0021	0.0425	0.0436
Toxoplasma gondii	histone lysine acetyltransferase GCN5-B	0.0043	0.134	0.2766
Loa Loa (eye worm)	hypothetical protein	0.0016	0.0199	0.0204
Schistosoma mansoni	thyroid hormone receptor	0.0021	0.0425	0.0746
Loa Loa (eye worm)	hypothetical protein	0.0016	0.0199	0.0204
Loa Loa (eye worm)	hypothetical protein	0.0016	0.0199	0.0204
Echinococcus multilocularis	solute carrier family 22	0.0016	0.0199	0.0204
Loa Loa (eye worm)	hypothetical protein	0.0016	0.0199	0.0204
Brugia malayi	Steroid receptor seven-up type 2	0.0021	0.0425	0.0436
Trichomonas vaginalis	bromodomain-containing protein, putative	0.0043	0.134	0.1164
Loa Loa (eye worm)	hypothetical protein	0.0016	0.0199	0.0204
Schistosoma mansoni	sugar transporter	0.0016	0.0199	0.0349
Loa Loa (eye worm)	nuclear Hormone Receptor family member	0.0021	0.0425	0.0436
Echinococcus granulosus	solute carrier family 2 facilitated glucose	0.0114	0.4325	0.4437
Loa Loa (eye worm)	nuclear hormone receptor family member nhr-49	0.0021	0.0425	0.0436
Schistosoma mansoni	gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2	0.0147	0.57	1
Schistosoma mansoni	glucose transport protein	0.0114	0.4325	0.7588
Entamoeba histolytica	hypothetical protein	0.0077	0.2769	1
Leishmania major	glucose transporter, lmgt2	0.0035	0.1013	1
Trypanosoma cruzi	hexose transporter, putative	0.0035	0.1013	1
Echinococcus multilocularis	thyroid hormone receptor alpha	0.0021	0.0425	0.0436
Plasmodium falciparum	histone acetyltransferase GCN5	0.004	0.1189	0.2399
Loa Loa (eye worm)	nuclear hormone receptor family member nhr-40	0.0021	0.0425	0.0436
Loa Loa (eye worm)	hypothetical protein	0.0016	0.0199	0.0204
Schistosoma mansoni	sugar transporter	0.0016	0.0199	0.0349
Schistosoma mansoni	thyroid hormone receptor	0.0021	0.0425	0.0746
Loa Loa (eye worm)	hypothetical protein	0.0016	0.0199	0.0204
Loa Loa (eye worm)	hypothetical protein	0.0021	0.0425	0.0436
Echinococcus granulosus	histone lysine methyltransferase setb	0.0031	0.0844	0.0866
Brugia malayi	hypothetical protein	0.0016	0.0199	0.0204
Toxoplasma gondii	histone lysine acetyltransferase GCN5-A	0.0043	0.134	0.2766
Brugia malayi	hypothetical protein	0.0243	0.9748	1
Loa Loa (eye worm)	hypothetical protein	0.0021	0.0425	0.0436
Loa Loa (eye worm)	nuclear hormone receptor family member nhr-14	0.0021	0.0425	0.0436
Onchocerca volvulus		0.0031	0.0844	0.0658
Echinococcus multilocularis	FTZ F1 alpha	0.0021	0.0425	0.0436
Trichomonas vaginalis	set domain proteins, putative	0.0249	1	1
Schistosoma mansoni	glucose transport protein	0.0114	0.4325	0.7588
Echinococcus multilocularis	guanine nucleotide binding protein G(s) subunit	0.0047	0.1501	0.154
Loa Loa (eye worm)	hypothetical protein	0.0021	0.0425	0.0436
Schistosoma mansoni	nuclear hormone receptor nor-1/nor-2	0.0021	0.0425	0.0746
Brugia malayi	Major Facilitator Superfamily protein	0.0016	0.0199	0.0204
Schistosoma mansoni	coup transcription factor	0.0021	0.0425	0.0746
Brugia malayi	major facilitator superfamily protein	0.0016	0.0199	0.0204
Toxoplasma gondii	histone lysine methyltransferase SET/SUV39	0.0031	0.0844	0.1563
Brugia malayi	hypothetical protein	0.0016	0.0199	0.0204
Echinococcus granulosus	solute carrier family 2 facilitated glucose	0.0114	0.4325	0.4437
Loa Loa (eye worm)	hypothetical protein	0.0031	0.0844	0.0866
Echinococcus granulosus	guanine nucleotide binding protein Gs subunit	0.0047	0.1501	0.154
Brugia malayi	Sugar transporter family protein	0.0016	0.0199	0.0204
Trichomonas vaginalis	sugar transporter, putative	0.0035	0.1013	0.083
Leishmania major	glucose transporter, lmgt3	0.0035	0.1013	1
Loa Loa (eye worm)	hypothetical protein	0.0021	0.0425	0.0436
Schistosoma mansoni	Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein)	0.0047	0.1501	0.2634
Schistosoma mansoni	hypothetical protein	0.0077	0.2769	0.4858
Mycobacterium ulcerans	sugar-transport integral membrane protein SugI	0.0016	0.0199	0.5
Brugia malayi	Nuclear hormone receptor family member nhr-41	0.0021	0.0425	0.0436
Trypanosoma brucei	glucose transporter, putative	0.0035	0.1013	1
Trichomonas vaginalis	sugar transporter, putative	0.0035	0.1013	0.083
Trypanosoma brucei	THT1 - hexose transporter, putative	0.0035	0.1013	1
Schistosoma mansoni	Tr4/Tr2 (homologue)	0.0021	0.0425	0.0746
Loa Loa (eye worm)	nuclear hormone receptor family member nhr-41	0.0021	0.0425	0.0436
Echinococcus multilocularis	solute carrier family 2, facilitated glucose	0.0114	0.4325	0.4437
Loa Loa (eye worm)	hypothetical protein	0.0021	0.0425	0.0436
Echinococcus granulosus	guanine nucleotide binding protein Gs subunit	0.0047	0.1501	0.154
Trichomonas vaginalis	glucose transporter, putative	0.0035	0.1013	0.083
Echinococcus granulosus	retinoic acid receptor rxr beta a	0.0021	0.0425	0.0436
Brugia malayi	Major Facilitator Superfamily protein	0.0016	0.0199	0.0204
Schistosoma mansoni	survival motor neuron protein	0.005	0.1609	0.2823
Brugia malayi	steroid hormone receptor	0.0021	0.0425	0.0436
Loa Loa (eye worm)	steroid hormone receptor	0.0021	0.0425	0.0436
Schistosoma mansoni	histone-lysine n-methyltransferase setb1	0.0031	0.0844	0.1481
Brugia malayi	acetyltransferase, GNAT family protein	0.0147	0.57	0.5847
Schistosoma mansoni	FTZ-F1 nuclear receptor-like protein	0.0021	0.0425	0.0746
Mycobacterium tuberculosis	Probable dicarboxylic acid transport integral membrane protein KgtP (dicarboxylate transporter)	0.0016	0.0199	0.5
Entamoeba histolytica	hypothetical protein	0.0077	0.2769	1
Onchocerca volvulus	Protein ultraspiracle homolog	0.0021	0.0425	0.0231
Loa Loa (eye worm)	hypothetical protein	0.0016	0.0199	0.0204
Trypanosoma brucei	glucose transporter, putative	0.0035	0.1013	1
Trichomonas vaginalis	cat eye syndrome critical region protein 2, cscr2, putative	0.0043	0.134	0.1164
Entamoeba histolytica	hypothetical protein	0.0077	0.2769	1
Echinococcus granulosus	solute carrier family 22	0.0016	0.0199	0.0204
Trypanosoma brucei	glucose transporter 1E	0.0035	0.1013	1
Echinococcus multilocularis	General substrate transporter	0.0098	0.365	0.3744
Echinococcus granulosus	FTZ F1 alpha	0.0021	0.0425	0.0436
Trypanosoma brucei	glucose transporter, putative	0.0035	0.1013	1
Onchocerca volvulus	Bile acid receptor homolog	0.0021	0.0425	0.0231
Trichomonas vaginalis	conserved hypothetical protein	0.0114	0.4325	0.421
Echinococcus granulosus	survival motor neuron protein 1	0.0243	0.9748	1
Echinococcus granulosus	Nuclear hormone receptor family member nhr 41	0.0021	0.0425	0.0436
Trypanosoma brucei	glucose transporter, putative	0.0035	0.1013	1
Trypanosoma brucei	glucose transporter, putative	0.0035	0.1013	1
Echinococcus multilocularis	synaptic vesicle 2 protein	0.0016	0.0199	0.0204
Echinococcus multilocularis	gcn5proteinral control of amino acid synthesis	0.0147	0.57	0.5847
Echinococcus multilocularis	solute carrier family 22	0.0016	0.0199	0.0204
Schistosoma mansoni	glucose transporter	0.0016	0.0199	0.0349
Brugia malayi	Nuclear hormone receptor family member nhr-49	0.0021	0.0425	0.0436
Onchocerca volvulus	Steroid hormone receptor family member cnr14 homolog	0.0021	0.0425	0.0231
Echinococcus multilocularis	solute carrier family 2 facilitated glucose	0.0114	0.4325	0.4437
Echinococcus multilocularis	ecdysone induced protein 78C	0.0021	0.0425	0.0436
Trichomonas vaginalis	conserved hypothetical protein	0.0035	0.1013	0.083
Plasmodium falciparum	hexose transporter	0.0114	0.4325	1
Echinococcus multilocularis	solute carrier family 2 facilitated glucose	0.0114	0.4325	0.4437
Loa Loa (eye worm)	hypothetical protein	0.0021	0.0425	0.0436
Brugia malayi	Nuclear hormone receptor family member nhr-19	0.0021	0.0425	0.0436
Trypanosoma brucei	THT1 - hexose transporter, putative	0.0035	0.1013	1
Loa Loa (eye worm)	hypothetical protein	0.0016	0.0199	0.0204
Brugia malayi	hypothetical protein	0.0077	0.2769	0.2841
Echinococcus multilocularis	hepatocyte nuclear factor 4 alpha	0.0021	0.0425	0.0436
Loa Loa (eye worm)	pre-SET domain-containing protein family protein	0.0219	0.8728	0.8954
Trypanosoma cruzi	hexose transporter	0.0035	0.1013	1
Echinococcus multilocularis	guanine nucleotide binding protein G(s) subunit	0.0047	0.1501	0.154
Schistosoma mansoni	sugar transporter	0.0016	0.0199	0.0349
Brugia malayi	Nuclear hormone receptor family member nhr-25	0.0021	0.0425	0.0436
Schistosoma mansoni	hypothetical protein	0.0114	0.4325	0.7588
Schistosoma mansoni	retinoic acid receptor RXR	0.0021	0.0425	0.0746
Echinococcus granulosus	FTZ F1 nuclear receptor protein	0.0021	0.0425	0.0436
Echinococcus multilocularis	Basic leucine zipper (bZIP) transcription	0.0077	0.2769	0.2841
Toxoplasma gondii	facilitative glucose transporter GT1	0.0114	0.4325	1
Schistosoma mansoni	histone-lysine n-methyltransferase setb1	0.0031	0.0844	0.1481
Trypanosoma cruzi	hexose transporter, putative	0.0035	0.1013	1
Schistosoma mansoni	nuclear hormone receptor	0.0021	0.0425	0.0746
Echinococcus granulosus	nuclear receptor 2DBD gamma	0.0021	0.0425	0.0436
Trypanosoma cruzi	hexose transporter, putative	0.0035	0.1013	1
Mycobacterium ulcerans	integral membrane transport protein	0.0016	0.0199	0.5
Schistosoma mansoni	Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein)	0.0047	0.1501	0.2634
Brugia malayi	Major Facilitator Superfamily protein	0.0016	0.0199	0.0204
Schistosoma mansoni	hypothetical protein	0.005	0.1609	0.2823
Brugia malayi	Nuclear hormone receptor family member nhr-40	0.0021	0.0425	0.0436
Schistosoma mansoni	transcription factor LCR-F1	0.0077	0.2769	0.4858
Brugia malayi	ecdysteroid receptor	0.0021	0.0425	0.0436
Echinococcus multilocularis	histone lysine methyltransferase setb histone lysine methyltransferase eggless	0.0031	0.0844	0.0866
Loa Loa (eye worm)	sugar transporter	0.0016	0.0199	0.0204
Brugia malayi	hypothetical protein	0.0016	0.0199	0.0204
Wolbachia endosymbiont of Brugia malayi	major facilitator superfamily permease	0.0016	0.0199	0.5
Schistosoma mansoni	histone-lysine n-methyltransferase suv9	0.0031	0.0844	0.1481
Echinococcus multilocularis	nuclear receptor 2DBD gamma	0.0021	0.0425	0.0436
Onchocerca volvulus		0.005	0.1609	0.1439
Brugia malayi	Nuclear hormone receptor family member nhr-31	0.0021	0.0425	0.0436
Loa Loa (eye worm)	nuclear hormone receptor family member nhr-31	0.0021	0.0425	0.0436
Brugia malayi	nuclear receptor NHR-88	0.0021	0.0425	0.0436
Echinococcus granulosus	ecdysone induced protein 78C	0.0021	0.0425	0.0436
Trypanosoma brucei	THT1 - hexose transporter, putative	0.0035	0.1013	1
Loa Loa (eye worm)	major facilitator superfamily transporter	0.0016	0.0199	0.0204
Brugia malayi	Pre-SET motif family protein	0.0219	0.8728	0.8954
Loa Loa (eye worm)	hypothetical protein	0.0016	0.0199	0.0204
Schistosoma mansoni	photoreceptor-specific nuclear receptor related	0.0021	0.0425	0.0746
Mycobacterium ulcerans	sugar transporter	0.0016	0.0199	0.5

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

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External resources for this compound

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Bibliographic References

No literature references available for this target.

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Detailed information for compound 736767