Detailed information for compound 737157

Basic information

Technical information
  • TDR Targets ID: 737157
  • Name: 5-[(2-naphthalen-1-yloxyacetyl)amino]benzene- 1,3-dicarboxylic acid
  • MW: 365.336 | Formula: C20H15NO6
  • H donors: 3 H acceptors: 5 LogP: 3.1 Rotable bonds: 7
    Rule of 5 violations (Lipinski): 1
  • SMILES: O=C(Nc1cc(cc(c1)C(=O)O)C(=O)O)COc1cccc2c1cccc2
  • InChi: 1S/C20H15NO6/c22-18(11-27-17-7-3-5-12-4-1-2-6-16(12)17)21-15-9-13(19(23)24)8-14(10-15)20(25)26/h1-10H,11H2,(H,21,22)(H,23,24)(H,25,26)
  • InChiKey: WEKPGAUEVMAPJS-UHFFFAOYSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

  • 5-[[2-(1-naphthyloxy)acetyl]amino]benzene-1,3-dicarboxylic acid
  • 5-[[2-(1-naphthyloxy)-1-oxoethyl]amino]benzene-1,3-dicarboxylic acid
  • 5-[[2-(1-naphthyloxy)acetyl]amino]isophthalic acid
  • 5-(2-naphthalen-1-yloxyethanoylamino)benzene-1,3-dicarboxylic acid
  • CBKinase1_015641
  • STK224150
  • CBKinase1_003241

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) hypothetical protein 0.0037 0.0185 0.0498
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0031 0.0117 0.0287
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0031 0.0117 0.0315
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0149 0.1383 0.3715
Loa Loa (eye worm) hypothetical protein 0.0251 0.2477 0.6653
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0159 0.1488 0.3995
Brugia malayi PHD-finger family protein 0.0024 0.0045 0.0091
Mycobacterium tuberculosis Conserved protein 0.0149 0.1383 0.1374
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0367 0.3724 1
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.0162 0.1103
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.015 0.1391 0.1855
Loa Loa (eye worm) hypothetical protein 0.0149 0.1383 0.3715
Schistosoma mansoni hypothetical protein 0.0251 0.2477 0.3388
Mycobacterium tuberculosis Conserved protein 0.0149 0.1383 0.1374
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0116 0.1031 0.2747
Plasmodium falciparum ataxin-2 like protein, putative 0.0026 0.0068 0.5
Echinococcus granulosus GPCR family 2 0.0116 0.1031 0.137
Schistosoma mansoni tar DNA-binding protein 0.0334 0.3368 0.4607
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0149 0.1383 0.1892
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0031 0.0117 0.012
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0021 0.0011 0.0029
Echinococcus multilocularis beta LACTamase domain containing family member 0.0149 0.1383 0.1542
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0035 0.0162 0.1096
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0031 0.0117 0.0287
Mycobacterium leprae conserved hypothetical protein 0.0149 0.1383 1
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0031 0.0117 0.0143
Schistosoma mansoni transcription factor LCR-F1 0.015 0.1391 0.1903
Mycobacterium tuberculosis Bacterioferritin BfrB 0.0034 0.0153 0.0142
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0162 0.1103
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0058 0.0408 0.0447
Brugia malayi TAR-binding protein 0.0334 0.3368 0.9043
Loa Loa (eye worm) hypothetical protein 0.0105 0.0907 0.2435
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0149 0.1383 0.1374
Echinococcus multilocularis neutral alpha glucosidase AB 0.0035 0.0162 0.017
Schistosoma mansoni alpha-glucosidase 0.0137 0.125 0.171
Onchocerca volvulus 0.0105 0.0907 0.6236
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.0162 0.1103
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0031 0.0117 0.0287
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0021 0.0011 0.0015
Brugia malayi Bromodomain containing protein 0.0037 0.0185 0.0468
Entamoeba histolytica hypothetical protein 0.015 0.1391 1
Trichomonas vaginalis D-aminoacylase, putative 0.0149 0.1383 1
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0031 0.0117 0.0287
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0031 0.0117 0.0287
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0031 0.0117 0.0315
Echinococcus multilocularis GPCR, family 2 0.0116 0.1031 0.1146
Schistosoma mansoni coup transcription factor 0.0031 0.0117 0.0161
Schistosoma mansoni microtubule-associated protein tau 0.0701 0.7311 1
Loa Loa (eye worm) hypothetical protein 0.0031 0.0117 0.0315
Loa Loa (eye worm) hypothetical protein 0.0031 0.0117 0.0315
Echinococcus granulosus FTZ F1 alpha 0.0031 0.0117 0.0143
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0162 0.1103
Schistosoma mansoni DNA polymerase eta 0.0021 0.0011 0.0015
Loa Loa (eye worm) hypothetical protein 0.0149 0.1383 0.3715
Schistosoma mansoni ferritin 0.0034 0.0153 0.0209
Schistosoma mansoni apoferritin-2 0.0034 0.0153 0.0209
Onchocerca volvulus 0.0092 0.0769 0.5151
Mycobacterium tuberculosis Probable esterase LipL 0.0149 0.1383 0.1374
Leishmania major alpha glucosidase II subunit, putative 0.0035 0.0162 0.1103
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0031 0.0117 0.0161
Loa Loa (eye worm) hypothetical protein 0.0031 0.0117 0.0315
Brugia malayi RNA recognition motif domain containing protein 0.0334 0.3368 0.9043
Schistosoma mansoni terminal deoxycytidyl transferase 0.0021 0.0011 0.0015
Schistosoma mansoni alpha glucosidase 0.0035 0.0162 0.0222
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0031 0.0117 0.0315
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0035 0.0162 0.0436
Brugia malayi beta-lactamase family protein 0.0149 0.1383 0.3696
Entamoeba histolytica hypothetical protein 0.015 0.1391 1
Trypanosoma brucei hypothetical protein, conserved 0.0149 0.1383 1
Brugia malayi MH2 domain containing protein 0.0116 0.1032 0.2751
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0035 0.0162 0.1096
Brugia malayi latrophilin 2 splice variant baaae 0.0251 0.2477 0.6643
Mycobacterium ulcerans bacterioferritin BfrB 0.0034 0.0153 0.1035
Toxoplasma gondii ABC1 family protein 0.0149 0.1383 1
Mycobacterium leprae Probable lipase LipE 0.0149 0.1383 1
Mycobacterium tuberculosis Probable lipase LipD 0.0149 0.1383 0.1374
Brugia malayi photoreceptor-specific nuclear receptor 0.0278 0.2774 0.7442
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0031 0.0117 0.0287
Loa Loa (eye worm) transcription factor SMAD2 0.0116 0.1032 0.2773
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0149 0.1383 0.1374
Brugia malayi Steroid receptor seven-up type 2 0.0031 0.0117 0.0287
Trichomonas vaginalis penicillin-binding protein, putative 0.0149 0.1383 1
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0116 0.1031 0.1146
Entamoeba histolytica hypothetical protein 0.015 0.1391 1
Schistosoma mansoni ferritin light chain 0.0034 0.0153 0.0209
Schistosoma mansoni tar DNA-binding protein 0.0334 0.3368 0.4607
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0031 0.0117 0.0143
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0116 0.1031 0.1146
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.0162 0.1103
Loa Loa (eye worm) hypothetical protein 0.0031 0.0117 0.0315
Plasmodium vivax hypothetical protein, conserved 0.0149 0.1383 1
Onchocerca volvulus 0.0149 0.1383 1
Brugia malayi steroid hormone receptor 0.0031 0.0117 0.0287
Trichomonas vaginalis ferritin, putative 0.0034 0.0153 0.1035
Onchocerca volvulus 0.0149 0.1383 1
Trichomonas vaginalis D-aminoacylase, putative 0.0149 0.1383 1
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0022 0.002 0.0027
Schistosoma mansoni steroid hormone receptor ad4bp 0.0031 0.0117 0.0161
Trypanosoma cruzi hypothetical protein, conserved 0.0149 0.1383 1
Echinococcus granulosus expressed protein 0.0034 0.0153 0.0191
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0149 0.1383 1
Mycobacterium ulcerans lipase LipD 0.0149 0.1383 1
Echinococcus granulosus ferritin 0.0034 0.0153 0.0191
Echinococcus granulosus microtubule associated protein 2 0.0701 0.7311 0.9809
Schistosoma mansoni ferritin 0.0034 0.0153 0.0209
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0031 0.0117 0.0287
Wolbachia endosymbiont of Brugia malayi bacterioferritin/cytochrome b1 0.0034 0.0153 0.5
Schistosoma mansoni retinoic acid receptor RXR 0.0031 0.0117 0.0161
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0031 0.0117 0.012
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0031 0.0117 0.0287
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0367 0.3724 1
Loa Loa (eye worm) hypothetical protein 0.0149 0.1383 0.3715
Echinococcus multilocularis thyroid hormone receptor alpha 0.0031 0.0117 0.012
Schistosoma mansoni hypothetical protein 0.015 0.1391 0.1903
Schistosoma mansoni tar DNA-binding protein 0.0334 0.3368 0.4607
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0035 0.016 0.0167
Mycobacterium ulcerans esterase/lipase LipP 0.0149 0.1383 1
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0031 0.0117 0.0287
Brugia malayi Glycosyl hydrolases family 31 protein 0.0159 0.1488 0.3977
Mycobacterium tuberculosis Probable lipase LipE 0.0149 0.1383 0.1374
Echinococcus granulosus tumor protein p63 0.0714 0.7453 1
Schistosoma mansoni alpha-glucosidase 0.0137 0.125 0.171
Schistosoma mansoni RAR-like nuclear receptor 0.0031 0.0117 0.0161
Schistosoma mansoni hypothetical protein 0.0116 0.1031 0.141
Giardia lamblia DINP protein human, muc B family 0.0021 0.0011 0.5
Trichomonas vaginalis maltase-glucoamylase, putative 0.0035 0.0162 0.1103
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0149 0.1383 0.3696
Loa Loa (eye worm) TAR-binding protein 0.0334 0.3368 0.9046
Brugia malayi nuclear receptor NHR-88 0.0031 0.0117 0.0287
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0031 0.0117 0.0143
Brugia malayi RNA binding protein 0.0334 0.3368 0.9043
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0035 0.0162 0.0717
Schistosoma mansoni hypothetical protein 0.0116 0.1031 0.141
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0031 0.0117 0.0161
Brugia malayi Nuclear hormone receptor-like 1 0.0031 0.0117 0.0287
Trypanosoma brucei glucosidase, putative 0.0035 0.0162 0.1103
Loa Loa (eye worm) latrophilin receptor protein 2 0.0116 0.1031 0.2768
Brugia malayi ecdysteroid receptor 0.0031 0.0117 0.0287
Brugia malayi hypothetical protein 0.0026 0.0068 0.0154
Mycobacterium tuberculosis Probable bacterioferritin BfrA 0.0034 0.0153 0.0142
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0031 0.0117 0.0287
Echinococcus multilocularis ferritin 0.0034 0.0153 0.016
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0031 0.0117 0.0315
Loa Loa (eye worm) steroid hormone receptor 0.0031 0.0117 0.0315
Echinococcus granulosus beta LACTamase domain containing family member 0.0149 0.1383 0.1844
Loa Loa (eye worm) hypothetical protein 0.0031 0.0117 0.0315
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0031 0.0117 0.0161
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0031 0.0117 0.0143
Schistosoma mansoni ferritin light chain 0.0034 0.0153 0.0209
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.015 0.1391 0.1551
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0031 0.0117 0.012
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0031 0.0117 0.0143
Schistosoma mansoni hypothetical protein 0.0116 0.1031 0.141
Echinococcus granulosus ecdysone induced protein 78C 0.0031 0.0117 0.0143
Echinococcus multilocularis tar DNA binding protein 0.0334 0.3368 0.3773
Echinococcus multilocularis lysosomal alpha glucosidase 0.0159 0.1488 0.1659
Loa Loa (eye worm) hypothetical protein 0.0278 0.2774 0.745
Entamoeba histolytica hypothetical protein 0.015 0.1391 1
Loa Loa (eye worm) hypothetical protein 0.0149 0.1383 0.3715
Loa Loa (eye worm) hypothetical protein 0.0367 0.3724 1
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0334 0.3368 0.9046
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0031 0.0117 0.0315
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0031 0.0117 0.0161
Trichomonas vaginalis sucrase-isomaltase, putative 0.0035 0.0162 0.1103
Schistosoma mansoni apoferritin-2 0.0034 0.0153 0.0209
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0149 0.1383 0.1374
Mycobacterium tuberculosis Probable hydrolase 0.0149 0.1383 0.1374
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0035 0.0162 0.1103
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0031 0.0117 0.0143
Schistosoma mansoni thyroid hormone receptor 0.0031 0.0117 0.0161
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0149 0.1383 0.1892
Loa Loa (eye worm) hypothetical protein 0.0021 0.0011 0.0029
Brugia malayi Glycosyl hydrolases family 31 protein 0.0035 0.0162 0.0408
Brugia malayi Latrophilin receptor protein 2 0.0116 0.1031 0.2747
Schistosoma mansoni tar DNA-binding protein 0.0334 0.3368 0.4607
Loa Loa (eye worm) MH2 domain-containing protein 0.0116 0.1032 0.2773
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0058 0.0408 0.0534
Trypanosoma brucei PAB1-binding protein , putative 0.0026 0.0068 0.0416
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.085 0.891 1
Loa Loa (eye worm) hypothetical protein 0.0031 0.0117 0.0315
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.0162 0.1103
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0031 0.0117 0.0315
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.0162 0.1103
Echinococcus multilocularis tumor protein p63 0.0714 0.7453 0.8363
Loa Loa (eye worm) hypothetical protein 0.0042 0.023 0.0618
Brugia malayi beta-lactamase 0.0149 0.1383 0.3696
Loa Loa (eye worm) hypothetical protein 0.0116 0.1031 0.2768
Schistosoma mansoni nuclear hormone receptor 0.0031 0.0117 0.0161
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0031 0.0117 0.012
Schistosoma mansoni ferritin 0.0034 0.0153 0.0209
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0035 0.0162 0.1103
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0031 0.0117 0.0287
Mycobacterium ulcerans beta-lactamase 0.0149 0.1383 1
Brugia malayi hypothetical protein 0.015 0.1391 0.3718
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0022 0.002 0.001
Leishmania major hypothetical protein, conserved 0.0149 0.1383 1
Echinococcus multilocularis ecdysone induced protein 78C 0.0031 0.0117 0.012
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0116 0.1031 0.137
Echinococcus granulosus lysosomal alpha glucosidase 0.0159 0.1488 0.1984
Schistosoma mansoni ferritin 0.0034 0.0153 0.0209
Leishmania major hypothetical protein, conserved 0.0026 0.0068 0.0416
Schistosoma mansoni thyroid hormone receptor 0.0031 0.0117 0.0161
Echinococcus multilocularis microtubule associated protein 2 0.0701 0.7311 0.8204
Brugia malayi nuclear hormone receptor 0.0031 0.0117 0.0287
Echinococcus granulosus fetal alzheimer antigen falz 0.0022 0.002 0.0012
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0031 0.0117 0.0161
Brugia malayi Bromodomain containing protein 0.0073 0.0568 0.1502
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0031 0.0117 0.0287
Plasmodium falciparum ataxin-2 like protein, putative 0.0026 0.0068 0.5
Loa Loa (eye worm) RNA binding protein 0.0334 0.3368 0.9046
Loa Loa (eye worm) hypothetical protein 0.0026 0.0068 0.0182
Trichomonas vaginalis D-aminoacylase, putative 0.0149 0.1383 1
Loa Loa (eye worm) hypothetical protein 0.0149 0.1383 0.3715
Trypanosoma cruzi PAB1-binding protein , putative 0.0026 0.0068 0.0416
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0031 0.0117 0.0287
Loa Loa (eye worm) hypothetical protein 0.004 0.021 0.0564
Trichomonas vaginalis esterase, putative 0.0149 0.1383 1
Schistosoma mansoni bromodomain containing protein 0.0062 0.0446 0.061
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0116 0.1031 0.137
Schistosoma mansoni cellular tumor antigen P53 0.0105 0.0907 0.124
Loa Loa (eye worm) hypothetical protein 0.0149 0.1383 0.3715
Echinococcus multilocularis lysosomal alpha glucosidase 0.0159 0.1488 0.1659
Echinococcus granulosus neutral alpha glucosidase AB 0.0035 0.0162 0.0203
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0031 0.0117 0.012
Echinococcus multilocularis expressed protein 0.0034 0.0153 0.016
Loa Loa (eye worm) beta-lactamase 0.0149 0.1383 0.3715
Mycobacterium tuberculosis Conserved protein 0.0149 0.1383 0.1374
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0031 0.0117 0.0315
Loa Loa (eye worm) hypothetical protein 0.0031 0.0117 0.0315
Brugia malayi Calcitonin receptor-like protein seb-1 0.0367 0.3724 1
Echinococcus granulosus tar DNA binding protein 0.0334 0.3368 0.4511
Mycobacterium ulcerans hypothetical protein 0.0149 0.1383 1
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0031 0.0117 0.0143
Echinococcus multilocularis FTZ F1 alpha 0.0031 0.0117 0.012
Mycobacterium ulcerans bacterioferritin BfrA 0.0034 0.0153 0.1035
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0035 0.016 0.02
Onchocerca volvulus 0.0149 0.1383 1
Trichomonas vaginalis penicillin-binding protein, putative 0.0149 0.1383 1
Treponema pallidum bacterioferrin (TpF1) 0.0034 0.0153 0.5
Schistosoma mansoni tar DNA-binding protein 0.0334 0.3368 0.4607
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0031 0.0117 0.012
Trypanosoma cruzi PAB1-binding protein , putative 0.0026 0.0068 0.0416
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0031 0.0117 0.0161
Schistosoma mansoni hypothetical protein 0.0116 0.1031 0.141
Brugia malayi beta-lactamase family protein 0.0149 0.1383 0.3696
Trypanosoma cruzi hypothetical protein, conserved 0.0149 0.1383 1
Loa Loa (eye worm) hypothetical protein 0.0069 0.0524 0.1406

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

If you have references for this compound, please enter them in a user comment (below) or Contact us.