Detailed information for compound 737200

Basic information

Technical information
  • TDR Targets ID: 737200
  • Name: CBKinase1_015683
  • MW: 484.588 | Formula: C24H24N2O5S2
  • H donors: 1 H acceptors: 4 LogP: 5.11 Rotable bonds: 8
    Rule of 5 violations (Lipinski): 1
  • SMILES: COC(=O)c1c(NC(=O)c2ccc(cc2)N(S(=O)(=O)c2ccccc2)C)sc2c1CCCC2
  • InChi: 1S/C24H24N2O5S2/c1-26(33(29,30)18-8-4-3-5-9-18)17-14-12-16(13-15-17)22(27)25-23-21(24(28)31-2)19-10-6-7-11-20(19)32-23/h3-5,8-9,12-15H,6-7,10-11H2,1-2H3,(H,25,27)
  • InChiKey: TZJKESLVHDJYDT-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • CBKinase1_003283
  • ZINC01139683
  • MLS000579001
  • SMR000198715
  • methyl 2-({4-[methyl(phenylsulfonyl)amino]benzoyl}amino)-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylate

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0023 0.0018 0.0049
Loa Loa (eye worm) TAR-binding protein 0.0065 0.0151 0.0149
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0049 0.0102 0.0102
Echinococcus granulosus fmrfamide receptor 0.0019 0.0006 0.0006
Echinococcus multilocularis rhodopsin orphan GPCR 0.0019 0.0006 0.0006
Schistosoma mansoni nuclear hormone receptor 0.0021 0.0011 0.0011
Entamoeba histolytica DNA topoisomerase II, putative 0.0143 0.04 0.1734
Loa Loa (eye worm) hypothetical protein 0.0021 0.0011 0.0009
Loa Loa (eye worm) hypothetical protein 0.0019 0.0006 0.0004
Loa Loa (eye worm) nuclear receptor NHR-67 0.0021 0.0011 0.0009
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0019 0.0006 0.0006
Echinococcus multilocularis DNA topoisomerase 1 0.0191 0.0554 0.0554
Loa Loa (eye worm) beta-lactamase 0.0075 0.0184 0.0182
Loa Loa (eye worm) hypothetical protein 0.0019 0.0006 0.0004
Echinococcus granulosus rhodopsin orphan GPCR 0.0019 0.0006 0.0006
Brugia malayi beta-lactamase family protein 0.0075 0.0184 0.0179
Loa Loa (eye worm) hypothetical protein 0.0532 0.1643 0.1642
Echinococcus granulosus nuclear receptor nhr 48 0.0021 0.0011 0.0011
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0039 0.007 0.0367
Schistosoma mansoni P2X receptor subunit 0.0208 0.0608 0.0608
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0044 0.0085 0.008
Schistosoma mansoni survival motor neuron protein 0.0051 0.0108 0.0108
Trichomonas vaginalis D-aminoacylase, putative 0.0075 0.0184 0.0926
Trichomonas vaginalis set domain proteins, putative 0.0252 0.075 0.3933
Echinococcus granulosus tm gpcr rhodopsin 0.0019 0.0006 0.0006
Echinococcus multilocularis mitogen activated protein kinase 0.0052 0.0111 0.0111
Echinococcus multilocularis neuropeptide FF receptor 2 0.0019 0.0006 0.0006
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0037 0.0062 0.0062
Schistosoma mansoni hypothetical protein 0.0173 0.0497 0.0497
Trypanosoma cruzi mitochondrial DNA topoisomerase II, putative 0.016 0.0456 0.3757
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0021 0.001 0.001
Loa Loa (eye worm) hypothetical protein 0.0021 0.0011 0.0009
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0049 0.0102 0.0102
Schistosoma mansoni biogenic amine receptor 0.0019 0.0006 0.0006
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0044 0.0085 0.008
Loa Loa (eye worm) hypothetical protein 0.0075 0.0184 0.0182
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0044 0.0085 0.008
Echinococcus multilocularis G protein coupled receptor 139 0.0019 0.0006 0.0006
Schistosoma mansoni tar DNA-binding protein 0.0065 0.0151 0.0151
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0532 0.1643 0.1643
Schistosoma mansoni adenoreceptor 0.0019 0.0006 0.0006
Echinococcus granulosus flap endonuclease 1 0.0028 0.0033 0.0033
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0021 0.0011 0.0011
Plasmodium vivax topoisomerase I, putative 0.0191 0.0554 1
Schistosoma mansoni neuropeptide f receptor 76f 0.0019 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0532 0.1643 0.1642
Echinococcus multilocularis zinc finger protein 0.002 0.0008 0.0008
Echinococcus multilocularis Niemann Pick C1 protein 0.0137 0.0381 0.0381
Trypanosoma brucei hypothetical protein, conserved 0.0075 0.0184 0.1468
Echinococcus granulosus carboxylesterase 5A 0.3148 1 1
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0023 0.0018 0.0049
Loa Loa (eye worm) hypothetical protein 0.0021 0.0011 0.0009
Trichomonas vaginalis CMGC family protein kinase 0.0052 0.0111 0.0534
Trichomonas vaginalis esterase, putative 0.0075 0.0184 0.0926
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0044 0.0085 0.0083
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0019 0.0006 0.0006
Schistosoma mansoni neuropeptide receptor 0.0019 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0532 0.1643 0.1642
Loa Loa (eye worm) hypothetical protein 0.0044 0.0085 0.0083
Echinococcus multilocularis mitogen activated protein kinase 3 0.0052 0.0111 0.0111
Loa Loa (eye worm) hypothetical protein 0.0019 0.0006 0.0004
Schistosoma mansoni amine GPCR 0.0019 0.0006 0.0006
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0021 0.0011 0.0011
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0019 0.0006 0.0006
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0023 0.0018 0.0049
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0061 0.0139 0.0139
Brugia malayi ImpB/MucB/SamB family protein 0.0021 0.001 0.0004
Loa Loa (eye worm) hypothetical protein 0.0021 0.0011 0.0009
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0064 0.0149 0.1173
Brugia malayi Nuclear hormone receptor E75 0.0021 0.0011 0.0005
Toxoplasma gondii DNA topoisomerase 2, putative 0.0143 0.04 0.7048
Echinococcus multilocularis rhodopsin orphan GPCR 0.0019 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0044 0.0083 0.0081
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0532 0.1643 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0019 0.0006 0.0006
Entamoeba histolytica acyl-CoA synthetase, putative 0.0023 0.0018 0.0035
Brugia malayi nuclear receptor NHR-88 0.0021 0.0011 0.0005
Loa Loa (eye worm) hypothetical protein 0.0075 0.0184 0.0182
Schistosoma mansoni hypothetical protein 0.0038 0.0067 0.0067
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0609 0.1891 0.8361
Onchocerca volvulus 0.0075 0.0184 0.109
Echinococcus multilocularis p2X purinoceptor 4 0.0208 0.0608 0.0608
Onchocerca volvulus 0.0021 0.0011 0.0032
Loa Loa (eye worm) steroid hormone receptor 0.0044 0.0085 0.0083
Echinococcus multilocularis g-protein coupled receptor 0.0019 0.0006 0.0006
Plasmodium vivax DNA gyrase subunit B, putative 0.0083 0.021 0.3401
Wolbachia endosymbiont of Brugia malayi DNA gyrase, topoisomerase II, B subunit, GyrB 0.0083 0.021 0.18
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0019 0.0006 0.0006
Echinococcus multilocularis neuropeptide Y receptor 0.0019 0.0006 0.0006
Echinococcus granulosus dna polymerase kappa 0.0021 0.001 0.001
Treponema pallidum fructose-bisphosphate aldolase 0.0609 0.1891 1
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0019 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0044 0.0085 0.0083
Onchocerca volvulus Huntingtin homolog 0.013 0.0361 0.217
Schistosoma mansoni intermediate filament proteins 0.0029 0.0036 0.0036
Schistosoma mansoni tar DNA-binding protein 0.0065 0.0151 0.0151
Loa Loa (eye worm) inositol-1 0.0039 0.007 0.0068
Schistosoma mansoni family C48 unassigned peptidase (C48 family) 0.0071 0.017 0.017
Echinococcus multilocularis ecdysone induced protein 78C 0.0044 0.0085 0.0085
Echinococcus granulosus Nuclear hormone receptor HR96 0.0021 0.0011 0.0011
Echinococcus multilocularis fmrfamide receptor 0.0019 0.0006 0.0006
Echinococcus granulosus FTZ F1 alpha 0.0044 0.0085 0.0085
Brugia malayi nuclear hormone receptor 0.0021 0.0011 0.0005
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0019 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0159 0.0452 0.045
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0019 0.0006 0.0006
Brugia malayi hypothetical protein 0.0252 0.0749 0.0743
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0044 0.0085 0.0085
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0023 0.0018 0.0049
Leishmania major 4-coumarate:coa ligase-like protein 0.0023 0.0018 0.0067
Echinococcus granulosus intermediate filament protein 0.0029 0.0036 0.0036
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0019 0.0006 0.0006
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0039 0.007 0.0505
Schistosoma mansoni acetylcholinesterase 0.0532 0.1643 0.1643
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0039 0.007 0.0296
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0019 0.0006 0.0006
Echinococcus granulosus tar DNA binding protein 0.0065 0.0151 0.0151
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0064 0.0149 0.1173
Schistosoma mansoni gliotactin 0.0532 0.1643 0.1643
Echinococcus multilocularis G-protein coupled receptor, putative 0.0019 0.0006 0.0006
Echinococcus multilocularis neuropeptide s receptor 0.0466 0.1433 0.1433
Loa Loa (eye worm) hypothetical protein 0.0252 0.0749 0.0747
Schistosoma mansoni steroid hormone receptor ad4bp 0.0044 0.0085 0.0085
Brugia malayi Carboxylesterase family protein 0.0532 0.1643 0.1639
Toxoplasma gondii ABC1 family protein 0.0075 0.0184 0.2904
Echinococcus multilocularis allatostatin A receptor 0.0019 0.0006 0.0006
Entamoeba histolytica Ulp1 protease family, C-terminal catalytic domain containing protein 0.0071 0.017 0.0712
Mycobacterium leprae conserved hypothetical protein 0.0075 0.0184 0.1739
Loa Loa (eye worm) hypothetical protein 0.0039 0.0069 0.0068
Giardia lamblia Kinase, CMGC MAPK 0.0052 0.0111 0.0447
Echinococcus multilocularis expressed conserved protein 0.009 0.0231 0.0231
Loa Loa (eye worm) hypothetical protein 0.0019 0.0006 0.0004
Echinococcus multilocularis neuropeptides capa receptor 0.0019 0.0006 0.0006
Echinococcus multilocularis muscleblind protein 1 0.0159 0.0452 0.0452
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.0018 0.0049
Loa Loa (eye worm) carboxylesterase 0.3148 1 1
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0044 0.0085 0.0085
Echinococcus granulosus tm gpcr rhodopsin 0.0019 0.0006 0.0006
Echinococcus granulosus X box binding protein 1 0.026 0.0776 0.0776
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0044 0.0085 0.008
Echinococcus multilocularis DNA topoisomerase 2 alpha 0.0143 0.04 0.04
Brugia malayi Probable DNA topoisomerase II 0.0143 0.04 0.0395
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0023 0.0018 0.0049
Loa Loa (eye worm) CYP4Cod1 0.0029 0.0038 0.0036
Echinococcus granulosus histone lysine methyltransferase setb 0.0049 0.0102 0.0102
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0019 0.0006 0.0006
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0044 0.0085 0.0083
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0065 0.0151 0.0149
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0064 0.0149 0.0147
Echinococcus granulosus DNA topoisomerase 2 alpha 0.0143 0.04 0.04
Echinococcus multilocularis neuropeptide receptor 0.0019 0.0006 0.0006
Trypanosoma cruzi hypothetical protein, conserved 0.0075 0.0184 0.1468
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0044 0.0085 0.0085
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0044 0.0085 0.0085
Trichomonas vaginalis D-aminoacylase, putative 0.0075 0.0184 0.0926
Brugia malayi PHD-finger family protein 0.0025 0.0026 0.002
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0609 0.1891 0.8361
Loa Loa (eye worm) cytochrome P450 family protein 0.0029 0.0038 0.0036
Echinococcus multilocularis BC026374 protein (S09 family) 0.0532 0.1643 0.1643
Schistosoma mansoni neuropeptide receptor 0.0019 0.0006 0.0006
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0044 0.0085 0.0083
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0019 0.0006 0.0006
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0052 0.0111 0.0847
Schistosoma mansoni nuclear receptor 0.0021 0.0011 0.0011
Loa Loa (eye worm) hypothetical protein 0.0019 0.0006 0.0004
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0021 0.0011 0.0011
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0052 0.0111 0.0847
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0021 0.001 0.001
Echinococcus granulosus lamin 0.0029 0.0036 0.0036
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0032 0.0046 0.0046
Schistosoma mansoni P2X receptor subunit 0.0208 0.0608 0.0608
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0039 0.007 0.0505
Trypanosoma cruzi mitochondrial DNA topoisomerase II, putative 0.016 0.0456 0.3757
Schistosoma mansoni microtubule-associated protein tau 0.1439 0.454 0.454
Echinococcus granulosus rhodopsin orphan GPCR 0.0019 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0532 0.1643 0.1642
Mycobacterium ulcerans esterase/lipase LipP 0.0075 0.0184 0.1066
Loa Loa (eye worm) hypothetical protein 0.0021 0.001 0.0008
Schistosoma mansoni hypothetical protein 0.0019 0.0006 0.0006
Loa Loa (eye worm) intermediate filament protein 0.0029 0.0036 0.0034
Brugia malayi Nuclear hormone receptor-like 1 0.0044 0.0085 0.008
Brugia malayi beta-lactamase 0.0075 0.0184 0.0179
Loa Loa (eye worm) hypothetical protein 0.0019 0.0006 0.0004
Loa Loa (eye worm) hypothetical protein 0.0019 0.0006 0.0004
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0052 0.0111 0.0847
Schistosoma mansoni hypothetical protein 0.004 0.0071 0.0071
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0075 0.0184 0.0184
Echinococcus multilocularis flap endonuclease 1 0.0028 0.0033 0.0033
Loa Loa (eye worm) hypothetical protein 0.0159 0.0452 0.045
Treponema pallidum DNA gyrase, subunit B (gyrB) 0.0083 0.021 0.0907
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0021 0.0011 0.0032
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0019 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0019 0.0006 0.0004
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0075 0.0184 0.0184
Echinococcus granulosus rhodopsin orphan GPCR 0.0019 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0058 0.013 0.0128
Loa Loa (eye worm) flap endonuclease-1 0.0028 0.0033 0.0031
Echinococcus granulosus tachykinin peptides receptor 99D 0.0019 0.0006 0.0006
Brugia malayi nuclear receptor RXR 0.0023 0.0019 0.0013
Loa Loa (eye worm) hypothetical protein 0.0019 0.0006 0.0004
Brugia malayi nuclear hormone receptor family member odr-7 0.0021 0.0011 0.0005
Schistosoma mansoni hypothetical protein 0.0173 0.0497 0.0497
Schistosoma mansoni nuclear receptor 0.0021 0.0011 0.0011
Brugia malayi Cytochrome P450 family protein 0.0029 0.0038 0.0033
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0039 0.007 0.0267
Onchocerca volvulus 0.0032 0.0046 0.0246
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0044 0.0085 0.008
Mycobacterium tuberculosis Conserved protein 0.0075 0.0184 0.1066
Entamoeba histolytica DNA repair and recombination protein RAD52, putative 0.0725 0.226 1
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0019 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.002 0.0007 0.0005
Loa Loa (eye worm) hypothetical protein 0.0019 0.0006 0.0004
Brugia malayi nuclear receptor RXR 0.0021 0.0011 0.0005
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0019 0.0006 0.0006
Trichomonas vaginalis Clan CE, family C48, Ulp1-like cysteine peptidase 0.0071 0.017 0.0852
Schistosoma mansoni retinoic acid receptor RXR 0.0044 0.0085 0.0085
Giardia lamblia DNA repair protein RAD52 0.0725 0.226 1
Echinococcus granulosus 7tm_1 domain containing protein 0.0019 0.0006 0.0006
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0019 0.0006 0.0006
Schistosoma mansoni P2X receptor subunit 0.0208 0.0608 0.0608
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0031 0.0042 0.0042
Echinococcus granulosus geminin 0.0173 0.0497 0.0497
Trypanosoma brucei flap endonuclease-1 (FEN-1), putative 0.0028 0.0033 0.0193
Plasmodium vivax SET domain protein, putative 0.0032 0.0046 0.0249
Loa Loa (eye worm) hypothetical protein 0.0019 0.0006 0.0004
Brugia malayi AMP-binding enzyme family protein 0.0023 0.0018 0.0012
Onchocerca volvulus 0.0051 0.0108 0.0627
Mycobacterium tuberculosis DNA gyrase (subunit A) GyrA (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (type II DNA topoisomerase) 0.0031 0.0042 0.0198
Toxoplasma gondii ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein 0.0083 0.021 0.3401
Brugia malayi hypothetical protein 0.0023 0.0019 0.0013
Echinococcus granulosus serotonin receptor 0.0019 0.0006 0.0006
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0023 0.0019 0.0019
Brugia malayi Carboxylesterase family protein 0.0532 0.1643 0.1639
Trichomonas vaginalis CMGC family protein kinase 0.0052 0.0111 0.0534
Echinococcus granulosus neuropeptide receptor 0.0019 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0019 0.0006 0.0004
Loa Loa (eye worm) hypothetical protein 0.0019 0.0006 0.0004
Echinococcus granulosus sentrin specific protease 8 0.0071 0.017 0.017
Brugia malayi latrophilin 2 splice variant baaae 0.0036 0.006 0.0055
Schistosoma mansoni neuropeptide F-like receptor 0.0019 0.0006 0.0006
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0035 0.0057 0.0407
Trypanosoma brucei protein kinase, putative 0.0052 0.0111 0.0847
Loa Loa (eye worm) hypothetical protein 0.013 0.0361 0.0359
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0023 0.0019 0.0017
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0064 0.0149 0.1173
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0052 0.0111 0.1489
Giardia lamblia Fructose-bisphosphate aldolase 0.0609 0.1891 0.8361
Loa Loa (eye worm) hypothetical protein 0.0019 0.0006 0.0004
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0044 0.0085 0.008
Echinococcus granulosus neuropeptide Y receptor 0.0019 0.0006 0.0006
Schistosoma mansoni DNA topoisomerase type I 0.0191 0.0554 0.0554
Echinococcus multilocularis dna polymerase kappa 0.0021 0.001 0.001
Echinococcus granulosus DNA topoisomerase 1 0.0191 0.0554 0.0554
Echinococcus multilocularis para nitrobenzyl esterase 0.0532 0.1643 0.1643
Toxoplasma gondii DNA topoisomerase I, putative 0.0191 0.0554 1
Echinococcus multilocularis neuroligin 0.0532 0.1643 0.1643
Loa Loa (eye worm) hypothetical protein 0.0075 0.0184 0.0182
Echinococcus multilocularis p2X purinoceptor 4 0.0208 0.0608 0.0608
Trypanosoma cruzi C-8 sterol isomerase, putative 0.0392 0.1197 1
Schistosoma mansoni nuclear hormone receptor 0.0044 0.0085 0.0085
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0044 0.0085 0.0085
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0064 0.0149 0.0149
Plasmodium vivax DNA gyrase subunit A, putative 0.0031 0.0042 0.0181
Echinococcus granulosus rhodopsin orphan GPCR 0.0019 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0036 0.006 0.0058
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0044 0.0085 0.0085
Loa Loa (eye worm) hypothetical protein 0.0019 0.0006 0.0004
Echinococcus granulosus Niemann Pick C1 protein 0.0096 0.025 0.025
Echinococcus granulosus neuroligin 0.0532 0.1643 0.1643
Echinococcus multilocularis geminin 0.0173 0.0497 0.0497
Mycobacterium tuberculosis DNA gyrase (subunit B) GyrB (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (type II DNA topoisomerase) 0.0083 0.021 0.1225
Leishmania major DNA topoisomerase ii 0.0135 0.0375 0.308
Loa Loa (eye worm) hypothetical protein 0.0096 0.025 0.0248
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0049 0.0102 0.0102
Schistosoma mansoni nuclear hormone receptor 0.0021 0.0011 0.0011
Loa Loa (eye worm) hypothetical protein 0.0042 0.0077 0.0075
Loa Loa (eye worm) hypothetical protein 0.005 0.0105 0.0103
Echinococcus multilocularis muscleblind protein 0.0159 0.0452 0.0452
Loa Loa (eye worm) hypothetical protein 0.0075 0.0184 0.0182
Schistosoma mansoni amine GPCR 0.0019 0.0006 0.0006
Leishmania major hypothetical protein, conserved 0.0075 0.0184 0.1468
Loa Loa (eye worm) hypothetical protein 0.0019 0.0006 0.0004
Loa Loa (eye worm) TYRA-2 protein 0.0019 0.0006 0.0004
Brugia malayi Inositol-1 0.0039 0.007 0.0064
Loa Loa (eye worm) hypothetical protein 0.0075 0.0184 0.0182
Echinococcus granulosus sterol regulatory element binding protein 0.0041 0.0075 0.0075
Loa Loa (eye worm) hypothetical protein 0.0019 0.0006 0.0004
Mycobacterium tuberculosis Probable lipase LipE 0.0075 0.0184 0.1066
Echinococcus granulosus zinc finger protein 0.002 0.0008 0.0008
Echinococcus granulosus Nuclear hormone receptor HR96 0.0021 0.0011 0.0011
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0609 0.1891 1
Brugia malayi RNA recognition motif domain containing protein 0.0065 0.0151 0.0145
Plasmodium falciparum DNA topoisomerase 2 0.0143 0.04 0.7048
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0019 0.0006 0.0004
Echinococcus multilocularis g protein coupled receptor 0.0019 0.0006 0.0006
Echinococcus granulosus p2X purinoceptor 4 0.0208 0.0608 0.0608
Brugia malayi follicle stimulating hormone receptor 0.0264 0.0788 0.0783
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0044 0.0085 0.008
Loa Loa (eye worm) hypothetical protein 0.0019 0.0006 0.0004
Plasmodium falciparum DNA gyrase subunit A 0.0031 0.0042 0.0181
Loa Loa (eye worm) nuclear hormone receptor 0.0021 0.0011 0.0009
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0038 0.0067 0.0067
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0053 0.0114 0.0108
Echinococcus granulosus g protein coupled receptor 0.0019 0.0006 0.0006
Trypanosoma cruzi DNA topoisomerase II, putative 0.0135 0.0375 0.308
Echinococcus multilocularis thyroid hormone receptor alpha 0.0044 0.0085 0.0085
Schistosoma mansoni lamin 0.0029 0.0036 0.0036
Echinococcus granulosus neuropeptide FF receptor 2 0.0019 0.0006 0.0006
Loa Loa (eye worm) RNA binding protein 0.0065 0.0151 0.0149
Loa Loa (eye worm) hypothetical protein 0.0097 0.0253 0.0251
Brugia malayi intermediate filament protein 0.0029 0.0036 0.003
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0032 0.0046 0.0046
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0019 0.0006 0.0006
Onchocerca volvulus Putative DNA topoisomerase 2, mitochondrial 0.0096 0.0252 0.1506
Brugia malayi Muscleblind-like protein 0.0159 0.0452 0.0447
Schistosoma mansoni flap endonuclease-1 0.0025 0.0024 0.0024
Loa Loa (eye worm) hypothetical protein 0.0019 0.0006 0.0004
Echinococcus granulosus neuropeptides capa receptor 0.0019 0.0006 0.0006
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0039 0.007 0.0505
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0019 0.0006 0.0006
Brugia malayi Pre-SET motif family protein 0.0222 0.0652 0.0647
Loa Loa (eye worm) hypothetical protein 0.0023 0.0019 0.0017
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0044 0.0085 0.0083
Brugia malayi Ulp1 protease family, C-terminal catalytic domain containing protein 0.0071 0.017 0.0165
Loa Loa (eye worm) hypothetical protein 0.0019 0.0006 0.0004
Entamoeba histolytica hypothetical protein 0.0038 0.0067 0.0252
Trypanosoma brucei cytochrome P450, putative 0.0029 0.0038 0.0239
Echinococcus granulosus muscleblind protein 0.0159 0.0452 0.0452
Trichomonas vaginalis spcc417.12 protein, putative 0.0532 0.1643 0.8684
Trypanosoma cruzi hypothetical protein 0.0071 0.017 0.135
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0044 0.0085 0.0486
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0532 0.1643 0.1643
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0019 0.0006 0.0006
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0021 0.0011 0.0011
Echinococcus granulosus acetylcholinesterase 0.3148 1 1
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0044 0.0085 0.0085
Entamoeba histolytica acyl-CoA synthetase, putative 0.0023 0.0018 0.0035
Onchocerca volvulus 0.0023 0.0018 0.0075
Echinococcus granulosus thyroid hormone receptor alpha 0.0021 0.0011 0.0011
Echinococcus granulosus rhodopsin orphan GPCR 0.0019 0.0006 0.0006
Echinococcus granulosus dro:myosuppressin receptor 0.0019 0.0006 0.0006
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0023 0.0019 0.0019
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0609 0.1891 1
Schistosoma mansoni coup transcription factor 0.0044 0.0085 0.0085
Loa Loa (eye worm) hypothetical protein 0.0019 0.0006 0.0004
Schistosoma mansoni hypothetical protein 0.0019 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0053 0.0114 0.0112
Loa Loa (eye worm) hypothetical protein 0.0532 0.1643 0.1642
Schistosoma mansoni amine GPCR 0.0019 0.0006 0.0006
Loa Loa (eye worm) cytochrome P450 family protein 0.0029 0.0038 0.0036
Schistosoma mansoni BC026374 protein (S09 family) 0.0532 0.1643 0.1643
Loa Loa (eye worm) hypothetical protein 0.0019 0.0006 0.0004
Loa Loa (eye worm) hypothetical protein 0.0021 0.0011 0.0009
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0044 0.0085 0.0083
Brugia malayi photoreceptor-specific nuclear receptor 0.0044 0.0085 0.008
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0021 0.0011 0.0011
Echinococcus multilocularis rhodopsin orphan GPCR 0.0019 0.0006 0.0006
Trypanosoma brucei DNA topoisomerase II alpha, putative 0.0135 0.0375 0.308
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.0018 0.0049
Loa Loa (eye worm) hypothetical protein 0.0023 0.0019 0.0017
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0044 0.0085 0.008
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0064 0.0149 0.0619
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0019 0.0006 0.0006
Onchocerca volvulus 0.0532 0.1643 1
Echinococcus multilocularis inositol monophosphatase 1 0.0039 0.007 0.007
Echinococcus multilocularis neuropeptide receptor 0.0019 0.0006 0.0006
Brugia malayi Carboxylesterase family protein 0.3148 1 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0019 0.0006 0.0006
Loa Loa (eye worm) Ulp1 protease 0.0071 0.017 0.0168
Loa Loa (eye worm) hypothetical protein 0.0019 0.0006 0.0004
Echinococcus granulosus Protein patched homolog 1 0.0041 0.0075 0.0075
Entamoeba histolytica Flap nuclease, putative 0.0028 0.0033 0.0102
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0044 0.0085 0.0083
Onchocerca volvulus 0.0029 0.0036 0.0186
Brugia malayi Nuclear hormone receptor-like 1 0.0023 0.0019 0.0013
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0029 0.0038 0.0173
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0021 0.0011 0.0011
Loa Loa (eye worm) hypothetical protein 0.0532 0.1643 0.1642
Echinococcus granulosus lamin dm0 0.0029 0.0036 0.0036
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0609 0.1891 1
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0044 0.0085 0.0085
Entamoeba histolytica acyl-coA synthetase, putative 0.0023 0.0018 0.0035
Echinococcus multilocularis nuclear receptor nhr 48 0.0021 0.0011 0.0011
Loa Loa (eye worm) hypothetical protein 0.013 0.0361 0.0359
Echinococcus multilocularis FTZ F1 alpha 0.0044 0.0085 0.0085
Leishmania major 4-coumarate:coa ligase-like protein 0.0023 0.0018 0.0067
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0023 0.0018 0.0018
Schistosoma mansoni DNA topoisomerase II 0.0143 0.04 0.04
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0019 0.0006 0.0006
Onchocerca volvulus Protein ultraspiracle homolog 0.0044 0.0085 0.0486
Brugia malayi beta-lactamase family protein 0.0075 0.0184 0.0179
Loa Loa (eye worm) hypothetical protein 0.0019 0.0006 0.0004
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0096 0.025 0.1066
Schistosoma mansoni zinc finger protein 0.0021 0.0011 0.0011
Loa Loa (eye worm) hypothetical protein 0.0021 0.0011 0.0009
Schistosoma mansoni opsin-like receptor 0.0019 0.0006 0.0006
Schistosoma mansoni opsin-like receptor 0.0019 0.0006 0.0006
Schistosoma mansoni growth hormone secretagogue receptor 0.0019 0.0006 0.0006
Echinococcus multilocularis somatostatin receptor 0.0019 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0049 0.0102 0.01
Echinococcus granulosus G protein coupled receptor 139 0.0019 0.0006 0.0006
Trichomonas vaginalis flap endonuclease-1, putative 0.0028 0.0033 0.0122
Brugia malayi hypothetical protein 0.0021 0.0011 0.0005
Trypanosoma cruzi cytochrome P450, putative 0.0029 0.0038 0.0239
Brugia malayi hypothetical protein 0.0021 0.0011 0.0005
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0075 0.0184 0.0182
Brugia malayi Niemann-Pick C1 protein precursor 0.0096 0.025 0.0244
Echinococcus multilocularis family S9 non peptidase ue (S09 family) 0.0532 0.1643 0.1643
Trichomonas vaginalis CMGC family protein kinase 0.0052 0.0111 0.0534
Loa Loa (eye worm) hypothetical protein 0.0044 0.0085 0.0083
Loa Loa (eye worm) hypothetical protein 0.0044 0.0085 0.0083
Loa Loa (eye worm) hypothetical protein 0.0028 0.0034 0.0032
Trichomonas vaginalis carboxylesterase domain containing protein, putative 0.0532 0.1643 0.8684
Loa Loa (eye worm) hypothetical protein 0.0021 0.0011 0.0009
Echinococcus multilocularis orexin receptor type 2 0.0019 0.0006 0.0006
Leishmania major DNA topoisomerase IB, large subunit 0.0191 0.0554 0.4583
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0044 0.0085 0.008
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0044 0.0085 0.0085
Loa Loa (eye worm) hypothetical protein 0.0019 0.0006 0.0004
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0052 0.0111 0.0847
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0019 0.0006 0.0006
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0044 0.0085 0.0083
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0029 0.0036 0.0034
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0044 0.0085 0.0085
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0298 0.0895 0.542
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0023 0.0019 0.0019
Onchocerca volvulus 0.0532 0.1643 1
Loa Loa (eye worm) hypothetical protein 0.0023 0.0019 0.0017
Loa Loa (eye worm) hypothetical protein 0.0072 0.0175 0.0173
Schistosoma mansoni thyroid hormone receptor 0.0044 0.0085 0.0085
Loa Loa (eye worm) hypothetical protein 0.0019 0.0006 0.0004
Mycobacterium ulcerans DNA gyrase subunit A 0.0031 0.0042 0.0198
Echinococcus granulosus somatostatin receptor 0.0019 0.0006 0.0006
Mycobacterium tuberculosis Probable lipase LipD 0.0075 0.0184 0.1066
Loa Loa (eye worm) hypothetical protein 0.0021 0.0011 0.0009
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0021 0.0011 0.0032
Brugia malayi hypothetical protein 0.0532 0.1643 0.1639
Echinococcus granulosus fetal alzheimer antigen falz 0.0023 0.0018 0.0018
Mycobacterium ulcerans lipase LipD 0.0075 0.0184 0.1066
Loa Loa (eye worm) hypothetical protein 0.0019 0.0006 0.0004
Brugia malayi DNA gyrase/topoisomerase IV, A subunit family protein 0.0143 0.04 0.0395
Entamoeba histolytica Rad52/22 family double-strand break repair protein, putative 0.0206 0.0603 0.2637
Loa Loa (eye worm) hypothetical protein 0.0019 0.0006 0.0004
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0035 0.0057 0.0287
Brugia malayi Cell division protein ftsZ 0.0155 0.0438 0.0433
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0019 0.0006 0.0006
Echinococcus multilocularis acetylcholinesterase 0.3148 1 1
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0023 0.0019 0.0019
Echinococcus multilocularis conserved hypothetical protein 0.0735 0.2291 0.2291
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0075 0.0184 0.1066
Loa Loa (eye worm) hypothetical protein 0.0044 0.0085 0.0083
Entamoeba histolytica hypothetical protein 0.0038 0.0067 0.0252
Echinococcus granulosus allatostatin A receptor 0.0019 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0023 0.0019 0.0017
Echinococcus multilocularis rhodopsin orphan GPCR 0.0019 0.0006 0.0006
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0039 0.007 0.0505
Schistosoma mansoni DNA polymerase eta 0.0021 0.001 0.001
Schistosoma mansoni P2X receptor subunit 0.0208 0.0608 0.0608
Brugia malayi tailless protein 0.0021 0.0011 0.0005
Trichomonas vaginalis Sentrin-specific protease, putative 0.0071 0.017 0.0852
Loa Loa (eye worm) TOPoisomerase family member 0.0143 0.04 0.0398
Mycobacterium ulcerans carboxylesterase, LipT 0.0532 0.1643 1
Loa Loa (eye worm) DR-78 0.0021 0.0011 0.0009
Schistosoma mansoni patched 1 0.0041 0.0075 0.0075
Brugia malayi Carboxylesterase family protein 0.0532 0.1643 0.1639
Echinococcus multilocularis serotonin receptor 0.0019 0.0006 0.0006
Brugia malayi hypothetical protein 0.013 0.0361 0.0356
Loa Loa (eye worm) G-protein coupled receptor 0.0019 0.0006 0.0004
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0863 0.2702 0.2702
Loa Loa (eye worm) neuropeptide F receptor 0.0019 0.0006 0.0004
Loa Loa (eye worm) hypothetical protein 0.0044 0.0085 0.0083
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0019 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0019 0.0006 0.0004
Trichomonas vaginalis CMGC family protein kinase 0.0052 0.0111 0.0534
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0019 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0019 0.0006 0.0004
Echinococcus multilocularis protein patched 0.0041 0.0075 0.0075
Mycobacterium leprae cell division protein FtsZ 0.0322 0.0974 1
Trichomonas vaginalis Clan CE, family C48, Ulp1-like cysteine peptidase 0.0071 0.017 0.0852
Brugia malayi nuclear hormone receptor 0.0044 0.0085 0.008
Trichomonas vaginalis D-aminoacylase, putative 0.0075 0.0184 0.0926
Echinococcus granulosus 7TM GPCR rhodopsin 0.0019 0.0006 0.0006
Echinococcus multilocularis serotonin receptor 0.0019 0.0006 0.0006
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0044 0.0085 0.008
Loa Loa (eye worm) PHD-finger family protein 0.0021 0.0012 0.001
Brugia malayi AMP-binding enzyme family protein 0.0023 0.0018 0.0012
Chlamydia trachomatis DNA gyrase subunit B 0.0066 0.0154 0.6674
Echinococcus multilocularis sex peptide receptor 0.0019 0.0006 0.0006
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0021 0.001 0.001
Schistosoma mansoni tar DNA-binding protein 0.0065 0.0151 0.0151
Echinococcus multilocularis p2X purinoceptor 4 0.0208 0.0608 0.0608
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0019 0.0006 0.0006
Schistosoma mansoni amine GPCR 0.0019 0.0006 0.0006
Entamoeba histolytica hypothetical protein 0.0038 0.0067 0.0252
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0064 0.0149 0.1173
Loa Loa (eye worm) hypothetical protein 0.0019 0.0006 0.0004
Mycobacterium tuberculosis Cell division protein FtsZ 0.0322 0.0974 0.5902
Brugia malayi orphan nuclear receptor NR2E1 0.0021 0.0011 0.0005
Loa Loa (eye worm) DNA topoisomerase I 0.0191 0.0554 0.0552
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0222 0.0652 0.065
Brugia malayi conserved hypotetical protein 0.0021 0.0011 0.0005
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0075 0.0184 0.1066
Loa Loa (eye worm) hypothetical protein 0.0021 0.0011 0.0009
Trypanosoma cruzi hypothetical protein, conserved 0.0075 0.0184 0.1468
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0532 0.1643 1
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0019 0.0006 0.0006
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0097 0.0255 0.0255
Loa Loa (eye worm) hypothetical protein 0.0023 0.0018 0.0016
Schistosoma mansoni DNA topoisomerase type I 0.0191 0.0554 0.0554
Echinococcus multilocularis transcription factor Dp 1 0.0037 0.0063 0.0063
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0053 0.0114 0.0112
Loa Loa (eye worm) hypothetical protein 0.0392 0.1197 0.1195
Leishmania major 4-coumarate:coa ligase-like protein 0.0023 0.0018 0.0067
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0019 0.0006 0.0006
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0039 0.007 0.0319
Loa Loa (eye worm) neuropeptide F receptor 0.0019 0.0006 0.0004
Brugia malayi nuclear receptor NHR-67 0.0021 0.0011 0.0005
Loa Loa (eye worm) acetylcholinesterase 1 0.3148 1 1
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0021 0.0011 0.0011
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0044 0.0085 0.0085
Loa Loa (eye worm) carboxylesterase 0.0532 0.1643 0.1642
Onchocerca volvulus 0.0044 0.0085 0.0486
Schistosoma mansoni biogenic amine receptor 0.0019 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0019 0.0006 0.0004
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0037 0.0062 0.0062
Echinococcus multilocularis rhodopsin orphan GPCR 0.0019 0.0006 0.0006
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0019 0.0006 0.0006
Echinococcus granulosus mitogen activated protein kinase 0.0052 0.0111 0.0111
Loa Loa (eye worm) hypothetical protein 0.0058 0.013 0.0128
Mycobacterium ulcerans DNA gyrase subunit B 0.0083 0.021 0.1225
Loa Loa (eye worm) hypothetical protein 0.0019 0.0006 0.0004
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0019 0.0006 0.0006
Mycobacterium tuberculosis Conserved protein 0.0075 0.0184 0.1066
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0032 0.0046 0.0249
Mycobacterium leprae Probable lipase LipE 0.0075 0.0184 0.1739
Schistosoma mansoni alpha-1 adrenergic receptor 0.0019 0.0006 0.0006
Echinococcus multilocularis dro:myosuppressin receptor 0.0019 0.0006 0.0006
Schistosoma mansoni hypothetical protein 0.004 0.0071 0.0071
Schistosoma mansoni biogenic amine (5HT) receptor 0.0019 0.0006 0.0006
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0075 0.0348
Schistosoma mansoni biogenic amine (5HT) receptor 0.0019 0.0006 0.0006
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0023 0.0018 0.0049
Schistosoma mansoni terminal deoxycytidyl transferase 0.0021 0.001 0.001
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0019 0.0006 0.0004
Loa Loa (eye worm) hypothetical protein 0.0018 0.0003 0.0001
Schistosoma mansoni serine/threonine protein kinase 0.0052 0.0111 0.0111
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0021 0.0011 0.0005
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0019 0.0006 0.0004
Loa Loa (eye worm) hypothetical protein 0.0019 0.0006 0.0004
Brugia malayi Steroid receptor seven-up type 2 0.0044 0.0085 0.008
Loa Loa (eye worm) hypothetical protein 0.0023 0.0018 0.0016
Loa Loa (eye worm) melatonin receptor type 1A 0.0019 0.0006 0.0004
Brugia malayi CHE-14 protein 0.0041 0.0075 0.007
Brugia malayi nuclear hormone receptor family member nhr-6 0.0021 0.0011 0.0005
Loa Loa (eye worm) carboxylesterase 0.0532 0.1643 0.1642
Echinococcus granulosus mitogen activated protein kinase 3 0.0052 0.0111 0.0111
Schistosoma mansoni inositol monophosphatase 0.0039 0.007 0.007
Plasmodium falciparum topoisomerase I 0.0191 0.0554 1
Echinococcus granulosus g-protein coupled receptor 0.0019 0.0006 0.0006
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0609 0.1891 1
Echinococcus granulosus rhodopsin orphan GPCR 0.0019 0.0006 0.0006
Brugia malayi hypothetical protein 0.0023 0.0019 0.0013
Schistosoma mansoni opsin-like receptor 0.0019 0.0006 0.0006
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0019 0.0006 0.0006
Echinococcus granulosus beta LACTamase domain containing family member 0.0075 0.0184 0.0184
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.3148 1 1
Trypanosoma cruzi cytochrome P450, putative 0.0029 0.0038 0.0239
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0298 0.0895 0.542
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0075 0.0184 0.1066
Mycobacterium ulcerans hypothetical protein 0.0023 0.0018 0.0049
Schistosoma mansoni thyroid hormone receptor 0.0044 0.0085 0.0085
Toxoplasma gondii DNA gyrase/topoisomerase IV, A subunit domain-containing protein 0.0031 0.0042 0.0181
Echinococcus multilocularis sterol regulatory element binding protein 0.0041 0.0075 0.0075
Loa Loa (eye worm) hypothetical protein 0.0023 0.0018 0.0016
Schistosoma mansoni hypothetical protein 0.0021 0.0012 0.0012
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0038 0.0067 0.0067
Loa Loa (eye worm) hypothetical protein 0.0019 0.0006 0.0004
Brugia malayi Bromodomain containing protein 0.0039 0.0069 0.0064
Brugia malayi steroid hormone receptor 0.0044 0.0085 0.008
Echinococcus granulosus hypothetical protein 0.0754 0.2352 0.2352
Brugia malayi ERG2 and Sigma1 receptor like protein 0.0392 0.1197 0.1192
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0044 0.0085 0.0085
Echinococcus multilocularis g protein coupled receptor 0.0019 0.0006 0.0006
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0044 0.0085 0.0085
Echinococcus granulosus BC026374 protein S09 family 0.0532 0.1643 0.1643
Brugia malayi Carboxylesterase family protein 0.0532 0.1643 0.1639
Echinococcus multilocularis fmrfamide receptor 0.0019 0.0006 0.0006
Schistosoma mansoni hypothetical protein 0.0019 0.0006 0.0006
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0021 0.0011 0.0011
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0019 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0019 0.0006 0.0004
Trichomonas vaginalis penicillin-binding protein, putative 0.0075 0.0184 0.0926
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0044 0.0085 0.0085
Echinococcus granulosus p2X purinoceptor 4 0.0208 0.0608 0.0608
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0019 0.0006 0.0006
Schistosoma mansoni neuropeptide receptor 0.0019 0.0006 0.0006
Trypanosoma cruzi DNA topoisomerase IB, large subunit, putative 0.0191 0.0554 0.4583
Leishmania major cytochrome p450-like protein 0.0029 0.0038 0.0239
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0019 0.0006 0.0006
Entamoeba histolytica hypothetical protein 0.0038 0.0067 0.0252
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0609 0.1891 1
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0052 0.0111 0.0109
Echinococcus granulosus peptide allatostatin:somatostatin 0.0019 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.02 0.0584 0.0582
Onchocerca volvulus 0.0075 0.0184 0.109
Loa Loa (eye worm) hypothetical protein 0.3148 1 1
Schistosoma mansoni RAR-like nuclear receptor 0.0044 0.0085 0.0085
Mycobacterium ulcerans hypothetical protein 0.0075 0.0184 0.1066
Loa Loa (eye worm) hypothetical protein 0.0021 0.0011 0.0009
Schistosoma mansoni hypothetical protein 0.004 0.0071 0.0071
Echinococcus multilocularis dna polymerase eta 0.0021 0.001 0.001
Trichomonas vaginalis Clan CE, family C48, Ulp1-like cysteine peptidase 0.0071 0.017 0.0852
Echinococcus multilocularis protein dispatched 1 0.0047 0.0094 0.0094
Loa Loa (eye worm) hypothetical protein 0.0019 0.0006 0.0004
Loa Loa (eye worm) G-protein coupled receptor 0.0019 0.0006 0.0004
Plasmodium falciparum DNA gyrase subunit B 0.0083 0.021 0.3401
Schistosoma mansoni hypothetical protein 0.0051 0.0108 0.0108
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0052 0.0111 0.0847
Echinococcus multilocularis neuropeptide Y receptor 0.0019 0.0006 0.0006
Brugia malayi Cell division protein ftsZ 0.0159 0.0453 0.0447
Echinococcus multilocularis sentrin specific protease 8 0.0071 0.017 0.017
Schistosoma mansoni biogenic amine receptor 0.0019 0.0006 0.0006
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0052 0.0111 0.0847
Entamoeba histolytica hypothetical protein 0.0206 0.0603 0.2637
Brugia malayi ImpB/MucB/SamB family protein 0.0021 0.001 0.0004
Echinococcus granulosus biogenic amine 5HT receptor 0.0019 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0019 0.0006 0.0004
Echinococcus multilocularis Niemann Pick C1 protein 0.0096 0.025 0.025
Echinococcus granulosus para nitrobenzyl esterase 0.0532 0.1643 0.1643
Loa Loa (eye worm) hypothetical protein 0.0029 0.0036 0.0034
Schistosoma mansoni tar DNA-binding protein 0.0065 0.0151 0.0151
Loa Loa (eye worm) hypothetical protein 0.0075 0.0184 0.0182
Onchocerca volvulus DNA topoisomerase 2 homolog 0.0096 0.0252 0.1506
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0044 0.0085 0.0085
Schistosoma mansoni bromodomain containing protein 0.0065 0.0151 0.0151
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0609 0.1891 1
Echinococcus multilocularis lamin 0.0029 0.0036 0.0036
Schistosoma mansoni lamin 0.0029 0.0036 0.0036
Echinococcus multilocularis rhodopsin orphan GPCR 0.0019 0.0006 0.0006
Leishmania major mitochondrial DNA topoisomerase II 0.016 0.0456 0.3757
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0044 0.0085 0.0085
Loa Loa (eye worm) hypothetical protein 0.0532 0.1643 0.1642
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0044 0.0085 0.008
Echinococcus granulosus p2X purinoceptor 4 0.0208 0.0608 0.0608
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0021 0.001 0.0008
Schistosoma mansoni hypothetical protein 0.0036 0.006 0.006
Echinococcus granulosus tm gpcr rhodopsin 0.0019 0.0006 0.0006
Brugia malayi DNA topoisomerase I 0.0191 0.0554 0.0548
Leishmania major C-8 sterol isomerase-like protein 0.0392 0.1197 1
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0064 0.0149 0.0149
Onchocerca volvulus 0.0532 0.1643 1
Trypanosoma brucei C-8 sterol isomerase, putative 0.0392 0.1197 1
Brugia malayi ecdysone receptor 0.0021 0.0011 0.0005
Trichomonas vaginalis inositol monophosphatase, putative 0.0039 0.007 0.0319
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0075 0.0184 0.1066
Schistosoma mansoni nuclear receptor nhr-48 0.0021 0.0011 0.0011
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0041 0.0075 0.0073
Loa Loa (eye worm) hypothetical protein 0.0021 0.0011 0.0009
Schistosoma mansoni hypothetical protein 0.026 0.0776 0.0776
Onchocerca volvulus Huntingtin homolog 0.013 0.0361 0.217
Leishmania major flap endonuclease-1 (FEN-1), putative 0.0028 0.0033 0.0193
Onchocerca volvulus 0.0029 0.0036 0.0186
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0019 0.0006 0.0006
Echinococcus granulosus acetylcholinesterase 0.3148 1 1
Loa Loa (eye worm) hypothetical protein 0.0097 0.0253 0.0251
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0044 0.0085 0.0085
Trypanosoma cruzi flap endonuclease-1 (FEN-1), putative 0.0028 0.0033 0.0193
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.0018 0.0049
Onchocerca volvulus DNA topoisomerase 2 homolog 0.0096 0.0252 0.1506
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0052 0.0111 0.0847
Loa Loa (eye worm) hypothetical protein 0.0041 0.0075 0.0073
Loa Loa (eye worm) hypothetical protein 0.0019 0.0006 0.0004
Echinococcus multilocularis microtubule associated protein 2 0.1439 0.454 0.454
Chlamydia trachomatis DNA gyrase subunit B 0.0083 0.021 1
Loa Loa (eye worm) hypothetical protein 0.0019 0.0006 0.0004
Echinococcus granulosus rhodopsin orphan GPCR 0.0019 0.0006 0.0006
Brugia malayi Bromodomain containing protein 0.0077 0.0189 0.0183
Schistosoma mansoni myosin xvIII 0.0019 0.0006 0.0006
Mycobacterium tuberculosis Possible penicillin-binding protein 0.048 0.1476 0.8977
Echinococcus multilocularis carboxylesterase 5A 0.3148 1 1
Echinococcus granulosus family S9 non peptidase ue S09 family 0.0532 0.1643 0.1643
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0609 0.1891 1
Giardia lamblia Flap structure-specific endonuclease 0.0028 0.0033 0.0102
Echinococcus granulosus Niemann Pick C1 protein 0.0137 0.0381 0.0381
Echinococcus multilocularis musashi 0.0029 0.0036 0.0036
Echinococcus multilocularis neuropeptide receptor A26 0.0466 0.1433 0.1433
Loa Loa (eye worm) hypothetical protein 0.0019 0.0006 0.0004
Trypanosoma brucei DNA topoisomerase II beta, putative 0.0135 0.0375 0.308
Loa Loa (eye worm) hypothetical protein 0.3148 1 1
Schistosoma mansoni hypothetical protein 0.0019 0.0006 0.0006
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0032 0.0046 0.0046
Schistosoma mansoni neuropeptide F-like receptor 0.0019 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0019 0.0006 0.0004
Trypanosoma cruzi DNA topoisomerase II, putative 0.0135 0.0375 0.308
Brugia malayi Pre-SET motif family protein 0.0032 0.0046 0.004
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0019 0.0006 0.0006
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0019 0.0006 0.0004
Onchocerca volvulus 0.0252 0.075 0.4544
Loa Loa (eye worm) hypothetical protein 0.0019 0.0006 0.0004
Echinococcus multilocularis rhodopsin orphan GPCR 0.0019 0.0006 0.0006
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0019 0.0006 0.0006
Brugia malayi hypothetical protein 0.0038 0.0067 0.0061
Echinococcus granulosus g protein coupled receptor 0.0019 0.0006 0.0006
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0061 0.0139 0.0139
Mycobacterium tuberculosis Carboxylesterase LipT 0.0532 0.1643 1
Brugia malayi nuclear receptor NHR-88 0.0044 0.0085 0.008
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0023 0.0018 0.0018
Schistosoma mansoni histamine h1 receptor 0.0019 0.0006 0.0006
Brugia malayi Nuclear hormone receptor E75 0.0021 0.0011 0.0005
Onchocerca volvulus Bile acid receptor homolog 0.0044 0.0085 0.0486
Echinococcus granulosus neuropeptide receptor A26 0.0466 0.1433 0.1433
Brugia malayi DNA topoisomerase II, alpha isozyme 0.0143 0.04 0.0395
Mycobacterium ulcerans cell division protein FtsZ 0.0322 0.0974 0.5902
Onchocerca volvulus 0.0075 0.0184 0.109
Schistosoma mansoni zinc finger protein 0.002 0.0008 0.0008
Brugia malayi MAP kinase sur-1 0.0052 0.0111 0.0105
Echinococcus multilocularis X box binding protein 1 0.026 0.0776 0.0776
Brugia malayi Flap endonuclease-1 0.0028 0.0033 0.0027
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0039 0.007 0.0711
Loa Loa (eye worm) hypothetical protein 0.0019 0.0006 0.0004
Plasmodium vivax hypothetical protein, conserved 0.0075 0.0184 0.2904
Brugia malayi AMP-binding enzyme family protein 0.0023 0.0018 0.0012
Echinococcus granulosus inositol monophosphatase 1 0.0039 0.007 0.007
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0039 0.007 0.0319
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0075 0.0184 0.0179
Echinococcus granulosus alpha 1A adrenergic receptor 0.0019 0.0006 0.0006
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0051 0.0108 0.0103
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0298 0.0895 0.9176
Trichomonas vaginalis penicillin-binding protein, putative 0.0075 0.0184 0.0926
Loa Loa (eye worm) hypothetical protein 0.002 0.0007 0.0005
Treponema pallidum cell division protein FtsZ 0.0322 0.0974 0.504
Loa Loa (eye worm) hypothetical protein 0.0019 0.0006 0.0004
Echinococcus multilocularis tar DNA binding protein 0.0065 0.0151 0.0151
Echinococcus granulosus neuropeptides capa receptor 0.0019 0.0006 0.0006
Brugia malayi RNA binding protein 0.0065 0.0151 0.0145
Echinococcus granulosus survival motor neuron protein 1 0.0252 0.0749 0.0749
Onchocerca volvulus 0.0532 0.1643 1
Schistosoma mansoni neuroligin 3 (S09 family) 0.0532 0.1643 0.1643
Loa Loa (eye worm) hypothetical protein 0.0044 0.0085 0.0083
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0019 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0023 0.0019 0.0017
Echinococcus granulosus dna polymerase eta 0.0021 0.001 0.001
Brugia malayi TAR-binding protein 0.0065 0.0151 0.0145
Echinococcus granulosus transcription factor Dp 1 0.0037 0.0063 0.0063
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0019 0.0006 0.0006
Brugia malayi ecdysteroid receptor 0.0044 0.0085 0.008
Loa Loa (eye worm) hypothetical protein 0.0044 0.0085 0.0083
Loa Loa (eye worm) hypothetical protein 0.0021 0.0011 0.0009
Loa Loa (eye worm) hypothetical protein 0.002 0.0007 0.0005
Trypanosoma brucei DNA topoisomerase IB, large subunit 0.0191 0.0554 0.4583
Schistosoma mansoni hypothetical protein 0.004 0.0071 0.0071
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0044 0.0085 0.008
Loa Loa (eye worm) hypothetical protein 0.0021 0.0011 0.0009
Mycobacterium ulcerans beta-lactamase 0.0075 0.0184 0.1066
Echinococcus granulosus neuropeptide Y receptor 0.0019 0.0006 0.0006
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0532 0.1643 0.1643
Schistosoma mansoni DNA topoisomerase type I 0.0191 0.0554 0.0554
Schistosoma mansoni tar DNA-binding protein 0.0065 0.0151 0.0151
Brugia malayi Intermediate filament tail domain containing protein 0.0029 0.0036 0.003
Echinococcus multilocularis beta LACTamase domain containing family member 0.0075 0.0184 0.0184
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0044 0.0085 0.0085
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0019 0.0006 0.0006
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0609 0.1891 1
Echinococcus granulosus sex peptide receptor 0.0019 0.0006 0.0006
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0019 0.0006 0.0006
Schistosoma mansoni amine GPCR 0.0019 0.0006 0.0006
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0021 0.0011 0.0011
Schistosoma mansoni neuropeptide receptor 0.0019 0.0006 0.0006
Echinococcus granulosus ecdysone induced protein 78C 0.0044 0.0085 0.0085
Mycobacterium tuberculosis Conserved protein 0.0075 0.0184 0.1066
Echinococcus granulosus expressed conserved protein 0.009 0.0231 0.0231
Onchocerca volvulus 0.0021 0.0011 0.0032
Echinococcus granulosus neuropeptide s receptor 0.0466 0.1433 0.1433
Brugia malayi Nuclear hormone receptor-like 1 0.0023 0.0019 0.0013
Echinococcus granulosus orexin receptor type 2 0.0019 0.0006 0.0006
Wolbachia endosymbiont of Brugia malayi cell division protein FtsZ 0.0322 0.0974 1
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0044 0.0085 0.008
Plasmodium vivax DNA topoisomerase II, putative 0.0143 0.04 0.7048
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0021 0.0011 0.0009
Echinococcus granulosus neuropeptide receptor 0.0019 0.0006 0.0006
Mycobacterium tuberculosis Probable esterase LipL 0.0075 0.0184 0.1066
Trichomonas vaginalis DNA topoisomerase II, putative 0.0143 0.04 0.2073
Onchocerca volvulus 0.0532 0.1643 1
Brugia malayi Calcitonin receptor-like protein seb-1 0.0053 0.0114 0.0108
Giardia lamblia DNA topoisomerase II 0.0135 0.0376 0.1628
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0064 0.0149 0.0149
Echinococcus multilocularis g protein coupled receptor 0.0019 0.0006 0.0006
Echinococcus granulosus g protein coupled receptor 0.0019 0.0006 0.0006
Echinococcus granulosus biogenic amine 5HT receptor 0.0019 0.0006 0.0006
Schistosoma mansoni transcription factor LCR-F1 0.0038 0.0067 0.0067
Echinococcus multilocularis acetylcholinesterase 0.3148 1 1
Mycobacterium tuberculosis Probable hydrolase 0.0075 0.0184 0.1066
Mycobacterium leprae Probable DNA gyrase (subunit B) GyrB (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (Type II DNA topoisomerase) 0.0037 0.0063 0.0469
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0064 0.0149 0.0144
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0264 0.0788 0.0786
Schistosoma mansoni inositol monophosphatase 0.0039 0.007 0.007
Echinococcus multilocularis lamin dm0 0.0029 0.0036 0.0036
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0044 0.0085 0.0085
Brugia malayi Cytochrome P450 family protein 0.0029 0.0038 0.0033
Echinococcus multilocularis survival motor neuron protein 1 0.0252 0.0749 0.0749
Echinococcus granulosus microtubule associated protein 2 0.1439 0.454 0.454
Trypanosoma brucei DNA topoisomerase ii 0.016 0.0456 0.3757
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0019 0.0006 0.0006
Echinococcus multilocularis neuropeptides capa receptor 0.0019 0.0006 0.0006

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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