Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | carboxylesterase domain containing protein, putative | 0.0024 | 0.011 | 0.0097 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0094 | 0.1625 | 0.1849 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.011 | 0.0111 |
Echinococcus multilocularis | dna polymerase kappa | 0.002 | 0.0013 | 0.0043 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0035 | 0.0341 | 0.0329 |
Echinococcus granulosus | dna polymerase eta | 0.0046 | 0.0585 | 0.1942 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0024 | 0.011 | 0.0405 |
Brugia malayi | Carboxylesterase family protein | 0.0144 | 0.2719 | 0.3103 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.011 | 0.0111 |
Entamoeba histolytica | hypothetical protein | 0.0074 | 0.1185 | 1 |
Echinococcus granulosus | terminal deoxycytidyl transferase rev1 | 0.002 | 0.0013 | 0.0043 |
Echinococcus multilocularis | acetylcholinesterase | 0.0144 | 0.2719 | 0.9025 |
Brugia malayi | hypothetical protein | 0.0074 | 0.1185 | 0.1343 |
Schistosoma mansoni | hypothetical protein | 0.0031 | 0.0256 | 0.094 |
Leishmania major | DNA polymerase eta, putative | 0.0046 | 0.0585 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0122 | 0.2233 | 0.821 |
Brugia malayi | Bromodomain containing protein | 0.0038 | 0.0402 | 0.0446 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.006 | 0.0893 | 0.3283 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0059 | 0.0862 | 0.286 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0077 | 0.1259 | 0.4179 |
Loa Loa (eye worm) | PHD-finger family protein | 0.002 | 0.0023 | 0.0011 |
Toxoplasma gondii | histone lysine methyltransferase SET/SUV39 | 0.006 | 0.0893 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.011 | 0.0111 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0094 | 0.1625 | 0.1849 |
Echinococcus granulosus | Mitotic checkpoint protein PRCC C terminal | 0.0122 | 0.2233 | 0.741 |
Brugia malayi | Carboxylesterase family protein | 0.0144 | 0.2719 | 0.3103 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.011 | 0.0111 |
Schistosoma mansoni | hypothetical protein | 0.0031 | 0.0256 | 0.094 |
Onchocerca volvulus | 0.006 | 0.0893 | 0.0791 | |
Echinococcus granulosus | acetylcholinesterase | 0.0144 | 0.2719 | 0.9025 |
Schistosoma mansoni | hypothetical protein | 0.0031 | 0.0256 | 0.094 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0031 | 0.0256 | 0.0848 |
Loa Loa (eye worm) | hypothetical protein | 0.0144 | 0.2719 | 0.3103 |
Brugia malayi | Pre-SET motif family protein | 0.042 | 0.8735 | 1 |
Loa Loa (eye worm) | carboxylesterase | 0.0024 | 0.011 | 0.0111 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0035 | 0.0351 | 0.1166 |
Echinococcus multilocularis | Mitotic checkpoint protein PRCC, C terminal | 0.0122 | 0.2233 | 0.741 |
Echinococcus granulosus | carboxylesterase 5A | 0.0144 | 0.2719 | 0.9025 |
Loa Loa (eye worm) | hypothetical protein | 0.0098 | 0.1716 | 0.1953 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0067 | 0.104 | 0.1178 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0404 | 0.0448 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.0158 | 0.3013 | 1 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0094 | 0.1625 | 0.5395 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0031 | 0.0256 | 0.0848 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0074 | 0.1185 | 0.4356 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0074 | 0.1185 | 0.3932 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0094 | 0.1625 | 0.5977 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0024 | 0.011 | 0.0405 |
Entamoeba histolytica | hypothetical protein | 0.0074 | 0.1185 | 1 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.006 | 0.0893 | 0.2963 |
Schistosoma mansoni | rab geranylgeranyl transferase alpha subunit | 0.002 | 0.0013 | 0.0048 |
Schistosoma mansoni | thyroid hormone receptor | 0.0132 | 0.2446 | 0.8993 |
Echinococcus multilocularis | neuroligin | 0.0024 | 0.011 | 0.0365 |
Schistosoma mansoni | acetyl-CoA C-acetyltransferase | 0.0022 | 0.0064 | 0.0234 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0098 | 0.1716 | 0.1953 |
Schistosoma mansoni | DNA polymerase eta | 0.0046 | 0.0585 | 0.2151 |
Echinococcus granulosus | para nitrobenzyl esterase | 0.0024 | 0.011 | 0.0365 |
Toxoplasma gondii | glycosyl hydrolase, family 31 protein | 0.0035 | 0.0341 | 0.0911 |
Schistosoma mansoni | alpha-glucosidase | 0.0136 | 0.2535 | 0.9322 |
Schistosoma mansoni | bromodomain containing protein | 0.0062 | 0.0939 | 0.3452 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0256 | 0.0278 |
Echinococcus granulosus | family S9 non peptidase ue S09 family | 0.0024 | 0.011 | 0.0365 |
Echinococcus granulosus | BC026374 protein S09 family | 0.0024 | 0.011 | 0.0365 |
Echinococcus granulosus | GPCR family 2 | 0.0031 | 0.0256 | 0.0848 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0144 | 0.2719 | 1 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0094 | 0.1625 | 0.5395 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0031 | 0.0256 | 0.0848 |
Echinococcus multilocularis | neutral alpha glucosidase AB | 0.0035 | 0.0341 | 0.1133 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0024 | 0.011 | 0.0405 |
Trypanosoma cruzi | DNA polymerase eta, putative | 0.0046 | 0.0585 | 1 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0059 | 0.0862 | 0.286 |
Trypanosoma brucei | DNA polymerase eta, putative | 0.0046 | 0.0585 | 1 |
Trichomonas vaginalis | neutral alpha-glucosidase ab precursor, putative | 0.0035 | 0.0341 | 0.0329 |
Loa Loa (eye worm) | hypothetical protein | 0.0067 | 0.104 | 0.1178 |
Brugia malayi | hypothetical protein | 0.0024 | 0.011 | 0.0111 |
Loa Loa (eye worm) | carboxylesterase | 0.0144 | 0.2719 | 0.3103 |
Leishmania major | DNA polymerase eta, putative | 0.0032 | 0.0286 | 0.4775 |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.0058 | 0.0844 | 0.2802 |
Leishmania major | alpha glucosidase II subunit, putative | 0.0035 | 0.0341 | 0.5741 |
Mycobacterium tuberculosis | Carboxylesterase LipT | 0.0024 | 0.011 | 1 |
Mycobacterium ulcerans | carboxylesterase, LipT | 0.0024 | 0.011 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0144 | 0.2719 | 0.3103 |
Trypanosoma cruzi | DNA polymerase eta, putative | 0.0032 | 0.0286 | 0.4775 |
Echinococcus granulosus | acetylcholinesterase | 0.0144 | 0.2719 | 0.9025 |
Loa Loa (eye worm) | glycosyl hydrolase family 31 protein | 0.0158 | 0.3013 | 0.344 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.0158 | 0.3013 | 1 |
Brugia malayi | Glycosyl hydrolases family 31 protein | 0.0158 | 0.3013 | 0.344 |
Schistosoma mansoni | hypothetical protein | 0.0074 | 0.1185 | 0.4356 |
Echinococcus multilocularis | terminal deoxycytidyl transferase rev1 | 0.002 | 0.0013 | 0.0043 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0094 | 0.1625 | 0.5395 |
Echinococcus granulosus | neuroligin | 0.0024 | 0.011 | 0.0365 |
Brugia malayi | Carboxylesterase family protein | 0.0024 | 0.011 | 0.0111 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0098 | 0.1716 | 0.1953 |
Echinococcus multilocularis | fetal alzheimer antigen, falz | 0.0022 | 0.0064 | 0.0212 |
Brugia malayi | PHD-finger family protein | 0.0025 | 0.0115 | 0.0117 |
Schistosoma mansoni | alpha-glucosidase | 0.0136 | 0.2535 | 0.9322 |
Brugia malayi | Carboxylesterase family protein | 0.0024 | 0.011 | 0.0111 |
Entamoeba histolytica | hypothetical protein | 0.0074 | 0.1185 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0094 | 0.1625 | 0.5977 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0074 | 0.1185 | 0.3932 |
Trichomonas vaginalis | maltase-glucoamylase, putative | 0.0035 | 0.0341 | 0.0329 |
Schistosoma mansoni | thyroid hormone receptor | 0.0132 | 0.2446 | 0.8993 |
Echinococcus multilocularis | GPCR, family 2 | 0.0031 | 0.0256 | 0.0848 |
Echinococcus multilocularis | acetylcholinesterase | 0.0144 | 0.2719 | 0.9025 |
Loa Loa (eye worm) | hypothetical protein | 0.007 | 0.1099 | 0.1245 |
Schistosoma mansoni | acetylcholinesterase | 0.0024 | 0.011 | 0.0405 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.011 | 0.0111 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0031 | 0.0256 | 0.0278 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0024 | 0.011 | 1 |
Brugia malayi | Glycosyl hydrolases family 31 protein | 0.0035 | 0.0341 | 0.0377 |
Schistosoma mansoni | BC026374 protein (S09 family) | 0.0024 | 0.011 | 0.0405 |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0.0585 | 0.0656 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0132 | 0.2446 | 0.8117 |
Schistosoma mansoni | gliotactin | 0.0024 | 0.011 | 0.0405 |
Echinococcus multilocularis | dna polymerase eta | 0.0046 | 0.0585 | 0.1942 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0035 | 0.0341 | 0.5741 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0035 | 0.0341 | 0.0329 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0077 | 0.1259 | 0.463 |
Onchocerca volvulus | 0.0091 | 0.1565 | 0.1472 | |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.0455 | 0.0506 |
Plasmodium vivax | SET domain protein, putative | 0.006 | 0.0893 | 0.5 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0035 | 0.0351 | 0.1166 |
Loa Loa (eye worm) | hypothetical protein | 0.0077 | 0.1259 | 0.1429 |
Schistosoma mansoni | hypothetical protein | 0.0067 | 0.104 | 0.3825 |
Echinococcus multilocularis | para nitrobenzyl esterase | 0.0024 | 0.011 | 0.0365 |
Entamoeba histolytica | glycosyl hydrolase, family 31 protein | 0.0035 | 0.0341 | 0.2803 |
Trichomonas vaginalis | neutral alpha-glucosidase ab precursor, putative | 0.0035 | 0.0341 | 0.0329 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.042 | 0.8735 | 1 |
Entamoeba histolytica | glycosyl hydrolase, family 31 protein | 0.0035 | 0.0341 | 0.2803 |
Loa Loa (eye worm) | carboxylesterase | 0.0024 | 0.011 | 0.0111 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.011 | 0.0111 |
Echinococcus granulosus | neutral alpha glucosidase AB | 0.0035 | 0.0341 | 0.1133 |
Loa Loa (eye worm) | glycosyl hydrolase family 31 protein | 0.0035 | 0.0341 | 0.0377 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0035 | 0.0341 | 0.5741 |
Trichomonas vaginalis | sucrase-isomaltase, putative | 0.0035 | 0.0341 | 0.0329 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0031 | 0.0256 | 0.0278 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0035 | 0.0341 | 0.0329 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0031 | 0.0256 | 0.0848 |
Echinococcus multilocularis | carboxylesterase 5A | 0.0144 | 0.2719 | 0.9025 |
Brugia malayi | Pre-SET motif family protein | 0.006 | 0.0893 | 0.1009 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.0144 | 0.2719 | 0.3103 |
Echinococcus granulosus | fetal alzheimer antigen falz | 0.0022 | 0.0064 | 0.0212 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.006 | 0.0893 | 0.3283 |
Trichomonas vaginalis | set domain proteins, putative | 0.0478 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0496 | 0.0553 |
Schistosoma mansoni | neuroligin 3 (S09 family) | 0.0024 | 0.011 | 0.0405 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.0046 | 0.0585 | 0.0656 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0094 | 0.1625 | 0.5395 |
Brugia malayi | Carboxylesterase family protein | 0.0024 | 0.011 | 0.0111 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.011 | 0.0111 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.0077 | 0.1259 | 0.4179 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0098 | 0.1716 | 0.1953 |
Echinococcus multilocularis | BC026374 protein (S09 family) | 0.0024 | 0.011 | 0.0365 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0031 | 0.0256 | 0.0278 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0035 | 0.0341 | 0.0329 |
Echinococcus multilocularis | family S9 non peptidase ue (S09 family) | 0.0024 | 0.011 | 0.0365 |
Schistosoma mansoni | alpha glucosidase | 0.0035 | 0.0341 | 0.1255 |
Schistosoma mansoni | terminal deoxycytidyl transferase | 0.002 | 0.0013 | 0.0048 |
Trypanosoma brucei | glucosidase, putative | 0.0035 | 0.0341 | 0.5741 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0035 | 0.0341 | 0.0329 |
Brugia malayi | Bromodomain containing protein | 0.0074 | 0.119 | 0.135 |
Brugia malayi | Carboxylesterase family protein | 0.0024 | 0.011 | 0.0111 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0077 | 0.1259 | 0.463 |
Trichomonas vaginalis | spcc417.12 protein, putative | 0.0024 | 0.011 | 0.0097 |
Giardia lamblia | DINP protein human, muc B family | 0.002 | 0.0013 | 0.5 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0094 | 0.1625 | 0.5977 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0024 | 0.011 | 1 |
Schistosoma mansoni | hypothetical protein | 0.002 | 0.0023 | 0.0083 |
Echinococcus granulosus | lysosomal alpha glucosidase | 0.0158 | 0.3013 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0031 | 0.0256 | 0.094 |
Entamoeba histolytica | hypothetical protein | 0.0074 | 0.1185 | 1 |
Echinococcus granulosus | dna polymerase kappa | 0.002 | 0.0013 | 0.0043 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.