Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0019 | 0.1694 | 0.5 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.1694 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.1694 | 1 |
Trypanosoma cruzi | DNA polymerase eta, putative | 0.0019 | 0.1694 | 0.5 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0035 | 0.6409 | 0.5677 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0019 | 0.1694 | 0.5 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0048 | 1 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.1694 | 1 |
Trichomonas vaginalis | DNA polymerase IV / kappa, putative | 0.0019 | 0.1694 | 0.5 |
Trypanosoma brucei | unspecified product | 0.0019 | 0.1694 | 1 |
Mycobacterium ulcerans | DNA polymerase IV | 0.0019 | 0.1694 | 0.5 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.1694 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.1694 | 1 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0019 | 0.1694 | 0.5 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0019 | 0.1694 | 0.5 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.1694 | 1 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0019 | 0.1694 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0035 | 0.6409 | 0.5677 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0035 | 0.6409 | 0.5677 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0048 | 1 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.1694 | 1 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0048 | 1 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0035 | 0.6409 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.1694 | 1 |
Giardia lamblia | DINP protein human, muc B family | 0.0019 | 0.1694 | 0.5 |
Leishmania major | DNA polymerase eta, putative | 0.0019 | 0.1694 | 0.5 |
Mycobacterium ulcerans | DNA polymerase IV | 0.0019 | 0.1694 | 0.5 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0019 | 0.1694 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0035 | 0.6409 | 1 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0019 | 0.1694 | 0.5 |
Leishmania major | DNA polymerase kappa, putative | 0.0019 | 0.1694 | 0.5 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.1694 | 1 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0048 | 1 | 1 |
Trichomonas vaginalis | DNA polymerase eta, putative | 0.0019 | 0.1694 | 0.5 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0048 | 1 | 1 |
Brugia malayi | hypothetical protein | 0.0035 | 0.6409 | 0.5677 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0019 | 0.1694 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0048 | 1 | 1 |
Leishmania major | DNA polymerase kappa, putative,DNA polymerase IV, putative | 0.0019 | 0.1694 | 0.5 |
Entamoeba histolytica | hypothetical protein | 0.0035 | 0.6409 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0048 | 1 | 1 |
Trypanosoma brucei | DNA polymerase eta, putative | 0.0019 | 0.1694 | 1 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0048 | 1 | 1 |
Mycobacterium tuberculosis | Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) | 0.0019 | 0.1694 | 0.5 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0035 | 0.6409 | 0.5677 |
Entamoeba histolytica | hypothetical protein | 0.0035 | 0.6409 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.1694 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.