Detailed information for compound 740013

Basic information

Technical information
  • TDR Targets ID: 740013
  • Name: N-(4-bromophenyl)pyrrolidine-1-carboxamide
  • MW: 269.138 | Formula: C11H13BrN2O
  • H donors: 1 H acceptors: 1 LogP: 2.29 Rotable bonds: 3
    Rule of 5 violations (Lipinski): 1
  • SMILES: O=C(N1CCCC1)Nc1ccc(cc1)Br
  • InChi: 1S/C11H13BrN2O/c12-9-3-5-10(6-4-9)13-11(15)14-7-1-2-8-14/h3-6H,1-2,7-8H2,(H,13,15)
  • InChiKey: YUAZOBUFYPAWQD-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • N-(4-bromophenyl)-1-pyrrolidinecarboxamide
  • IVK/0018141
  • AP-124/40215090
  • ZINC06728846

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus multilocularis zinc finger protein 0.0064 0.0746 0.0742
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0021 0.0159 0.0343
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0021 0.0153 0.0149
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0021 0.0159 0.0343
Trypanosoma brucei DNA polymerase IV, putative 0.0021 0.0153 0.1333
Schistosoma mansoni hypothetical protein 0.0033 0.0326 0.0326
Leishmania major cathepsin L-like protease 0.0017 0.0106 0.0678
Entamoeba histolytica recQ family helicase, putative 0.0014 0.0057 0.1404
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0086 0.1047 1
Loa Loa (eye worm) latrophilin receptor protein 2 0.0033 0.0326 0.0713
Schistosoma mansoni lamin 0.0087 0.107 0.107
Schistosoma mansoni RAR-like nuclear receptor 0.0021 0.0159 0.0159
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0114 0.1437 0.1433
Echinococcus multilocularis importin subunit beta 1 0.0032 0.0302 0.0297
Loa Loa (eye worm) hypothetical protein 0.0072 0.086 0.1897
Brugia malayi photoreceptor-specific nuclear receptor 0.0021 0.0159 0.0439
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0021 0.0159 0.0439
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0086 0.1047 1
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0023 0.0187 0.0517
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0036 0.0369 0.0369
Loa Loa (eye worm) hypothetical protein 0.0036 0.0369 0.0807
Entamoeba histolytica deoxycytidyl transferase, putative 0.0021 0.0153 0.3784
Loa Loa (eye worm) jmjC domain-containing protein 0.0036 0.0369 0.0807
Onchocerca volvulus 0.0017 0.0106 0.0302
Schistosoma mansoni hypothetical protein 0.0072 0.086 0.086
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0106 0.0238
Entamoeba histolytica Ran family GTPase 0.0023 0.0187 0.4618
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) 0.0086 0.1047 1
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0049 0.0546 0.0546
Echinococcus multilocularis cpg binding protein 0.0039 0.0401 0.0397
Echinococcus multilocularis ATP dependent Clp protease proteolytic subunit 0.0086 0.1047 0.1043
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0011 0.0014 0.001
Schistosoma mansoni terminal deoxycytidyl transferase 0.0021 0.0153 0.0153
Loa Loa (eye worm) hypothetical protein 0.0028 0.0256 0.0557
Onchocerca volvulus 0.0017 0.0106 0.0302
Loa Loa (eye worm) hypothetical protein 0.0087 0.1059 0.2339
Loa Loa (eye worm) hypothetical protein 0.0021 0.0159 0.0343
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0021 0.0159 0.0159
Onchocerca volvulus Cathepsin L homolog 0.0017 0.0106 0.0302
Plasmodium falciparum phd finger protein, putative 0.0063 0.0728 0.6948
Brugia malayi Cathepsin L-like precursor 0.0017 0.0106 0.0287
Brugia malayi Bromodomain containing protein 0.007 0.0831 0.2346
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0223 0.2932 0.649
Schistosoma mansoni jumonji domain containing protein 0.0036 0.0369 0.0369
Leishmania major cathepsin L-like protease 0.0017 0.0106 0.0678
Loa Loa (eye worm) CXXC zinc finger family protein 0.0031 0.0293 0.064
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0073 0.0876 0.0876
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0153 0.1333
Plasmodium vivax importin-beta 2, putative 0.0032 0.0302 0.2081
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0106 0.0238
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0266 0.3529 0.3526
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0039 0.0404 0.2809
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0026 0.0219 0.0579
Leishmania major hypothetical protein, conserved 0.0049 0.0535 0.6623
Schistosoma mansoni methyl-cpg binding protein mbd 0.0054 0.0612 0.0612
Brugia malayi RNA, U transporter 1 0.009 0.1105 0.3122
Loa Loa (eye worm) hypothetical protein 0.0021 0.0159 0.0343
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0086 0.1047 1
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0049 0.0546 0.1201
Schistosoma mansoni zinc finger protein 0.001 0.0004 0.0004
Schistosoma mansoni protein phosphatase 2C 0.0036 0.0369 0.0369
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0153 0.1333
Schistosoma mansoni DNA helicase recq5 0.0011 0.0013 0.0013
Loa Loa (eye worm) hypothetical protein 0.0086 0.1048 0.2314
Brugia malayi hypothetical protein 0.0011 0.0021 0.0047
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0039 0.0404 0.4813
Echinococcus multilocularis dna polymerase eta 0.0021 0.0153 0.0149
Echinococcus multilocularis thyroid hormone receptor alpha 0.0152 0.196 0.1956
Loa Loa (eye worm) hypothetical protein 0.0036 0.0369 0.0807
Echinococcus multilocularis cysteine protease 0.0017 0.0106 0.0101
Brugia malayi F/Y-rich N-terminus family protein 0.0037 0.0378 0.1059
Brugia malayi Calcitonin receptor-like protein seb-1 0.0106 0.132 0.3733
Leishmania major cathepsin L-like protease 0.0066 0.0779 1
Brugia malayi Importin beta-1 subunit 0.0032 0.0302 0.0844
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0066 0.0779 1
Brugia malayi Papain family cysteine protease containing protein 0.0017 0.0106 0.0287
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0063 0.0728 0.0728
Echinococcus granulosus intermediate filament protein 0.0087 0.107 0.1066
Trypanosoma cruzi DNA polymerase kappa, putative 0.0021 0.0153 0.1333
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0021 0.0159 0.0155
Loa Loa (eye worm) hypothetical protein 0.0032 0.0302 0.0659
Echinococcus multilocularis phd:f box containing protein 0.0036 0.0369 0.0364
Brugia malayi jmjC domain containing protein 0.0145 0.1858 0.5259
Plasmodium vivax SET domain protein, putative 0.0033 0.0314 0.2211
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0021 0.0159 0.0439
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0017 0.0106 0.1009
Schistosoma mansoni cathepsin F (C01 family) 0.0017 0.0106 0.0106
Schistosoma mansoni transcription factor LCR-F1 0.0039 0.0401 0.0401
Leishmania major cathepsin L-like protease 0.0066 0.0779 1
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0011 0.0013 0.0026
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0039 0.0404 0.4813
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.0131 0.1667 0.1663
Echinococcus granulosus cathepsin L cysteine proteinase 0.0017 0.0106 0.0101
Brugia malayi Bloom's syndrome protein homolog 0.0026 0.0223 0.062
Entamoeba histolytica hypothetical protein 0.0039 0.0401 0.9917
Plasmodium falciparum conserved Plasmodium membrane protein, unknown function 0.0022 0.0174 0.1659
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0033 0.0326 0.0322
Echinococcus multilocularis bloom syndrome protein 0.0026 0.0223 0.0219
Loa Loa (eye worm) bromodomain containing protein 0.0056 0.0638 0.1406
Trypanosoma brucei DNA polymerase IV, putative 0.0021 0.0153 0.1333
Schistosoma mansoni microtubule-associated protein tau 0.0736 1 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0066 0.0779 1
Schistosoma mansoni ap endonuclease 0.0039 0.0404 0.0404
Loa Loa (eye worm) hypothetical protein 0.0021 0.0159 0.0343
Brugia malayi Latrophilin receptor protein 2 0.0033 0.0326 0.0913
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0011 0.0021 0.0017
Echinococcus granulosus GPCR family 2 0.0033 0.0326 0.0322
Loa Loa (eye worm) hypothetical protein 0.0021 0.0159 0.0343
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0106 0.0238
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0106 0.0238
Schistosoma mansoni jumonji/arid domain-containing protein 0.0145 0.1858 0.1858
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0066 0.0779 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0066 0.0779 1
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0023 0.018 0.1715
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0033 0.0314 0.0314
Trypanosoma brucei unspecified product 0.0021 0.0153 0.1333
Echinococcus multilocularis peregrin 0.007 0.0831 0.0827
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0018 0.0107 0.0018
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0049 0.0546 0.0546
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0017 0.0106 0.0238
Plasmodium falciparum cysteine proteinase falcipain 3 0.0017 0.0106 0.1009
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0106 0.0238
Echinococcus multilocularis geminin 0.0176 0.229 0.2287
Trypanosoma cruzi ISWI complex protein 0.0049 0.0535 0.6623
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0106 0.0238
Onchocerca volvulus 0.0253 0.3354 1
Schistosoma mansoni peptidase Clp (S14 family) 0.0086 0.1047 0.1047
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0049 0.0546 0.1537
Schistosoma mansoni cpg binding protein 0.0039 0.0401 0.0401
Schistosoma mansoni jumonji domain containing protein 0.0224 0.2949 0.2949
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0087 0.1059 0.1055
Schistosoma mansoni ap endonuclease 0.0039 0.0404 0.0404
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0086 0.1047 0.5
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0338 0.4515 1
Giardia lamblia DINP protein human, muc B family 0.0021 0.0153 0.1954
Schistosoma mansoni DNA helicase recq1 0.0011 0.0013 0.0013
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0039 0.0404 0.386
Trichomonas vaginalis importin beta-1, putative 0.0026 0.0219 0.0579
Brugia malayi latrophilin 2 splice variant baaae 0.0072 0.086 0.2428
Trypanosoma brucei DNA polymerase eta, putative 0.0021 0.0153 0.1333
Echinococcus granulosus snurportin 1 0.0338 0.4515 0.4513
Loa Loa (eye worm) hypothetical protein 0.0041 0.0425 0.0933
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0021 0.0153 0.0329
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0106 0.0238
Loa Loa (eye worm) hypothetical protein 0.0042 0.0447 0.0982
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0017 0.0106 0.0225
Loa Loa (eye worm) cysteine protease 0.0017 0.0106 0.0225
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0021 0.0159 0.0155
Echinococcus multilocularis JmjC domain containing protein 4 0.0036 0.0369 0.0364
Brugia malayi hypothetical protein 0.0011 0.0021 0.0047
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0086 0.1047 1
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0086 0.1047 1
Brugia malayi CXXC zinc finger family protein 0.0031 0.0293 0.0819
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0087 0.1059 0.1059
Echinococcus granulosus PHD finger protein rhinoceros 0.0063 0.0728 0.0724
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0017 0.0106 0.0101
Treponema pallidum exodeoxyribonuclease (exoA) 0.0039 0.0404 0.1694
Loa Loa (eye worm) RecQ helicase 0.0026 0.0223 0.0485
Brugia malayi Cathepsin L-like precursor 0.0017 0.0106 0.0287
Trichomonas vaginalis DNA helicase recq1, putative 0.0026 0.0223 0.059
Echinococcus granulosus cpg binding protein 0.0039 0.0401 0.0397
Brugia malayi Nuclear hormone receptor-like 1 0.0021 0.0159 0.0439
Echinococcus multilocularis musashi 0.0087 0.107 0.1066
Schistosoma mansoni nuclear receptor 0.001 0.0004 0.0004
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0021 0.0159 0.0155
Brugia malayi ecdysteroid receptor 0.0021 0.0159 0.0439
Trichomonas vaginalis set domain proteins, putative 0.0253 0.3354 1
Brugia malayi nuclear receptor RXR 0.0011 0.0021 0.0047
Brugia malayi Cathepsin L-like precursor 0.0017 0.0106 0.0287
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0086 0.1047 0.5
Echinococcus granulosus bloom syndrome protein 0.0026 0.0223 0.0219
Trypanosoma brucei unspecified product 0.0014 0.0064 0.01
Echinococcus granulosus cathepsin l1 0.0012 0.0026 0.0022
Toxoplasma gondii PHD-finger domain-containing protein 0.0063 0.0728 0.6908
Loa Loa (eye worm) hypothetical protein 0.0041 0.0425 0.0933
Echinococcus granulosus lamin 0.0087 0.107 0.1066
Trypanosoma cruzi cysteine peptidase, putative 0.0066 0.0779 1
Schistosoma mansoni nuclear receptor nhr-48 0.001 0.0004 0.0004
Plasmodium vivax JmjC domain containing protein 0.0036 0.0369 0.2792
Echinococcus granulosus zinc finger protein 0.0064 0.0746 0.0742
Echinococcus granulosus JmjC domain containing protein 4 0.0036 0.0369 0.0364
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0066 0.0779 1
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0086 0.1047 1
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0029 0.027 0.027
Schistosoma mansoni blooms syndrome DNA helicase 0.002 0.0148 0.0148
Echinococcus granulosus jumonji domain containing protein 0.0087 0.1065 0.1061
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0021 0.0159 0.0159
Loa Loa (eye worm) hypothetical protein 0.0106 0.132 0.2917
Schistosoma mansoni bromodomain containing protein 0.0203 0.2657 0.2657
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0021 0.0159 0.0439
Echinococcus granulosus ATP dependent Clp protease proteolytic subunit 0.0086 0.1047 0.1043
Echinococcus multilocularis dna polymerase kappa 0.0021 0.0153 0.0149
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0153 0.1333
Loa Loa (eye worm) hypothetical protein 0.0011 0.0021 0.0037
Onchocerca volvulus 0.0012 0.0026 0.0066
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0106 0.0238
Brugia malayi steroid hormone receptor 0.0021 0.0159 0.0439
Toxoplasma gondii PHD-finger domain-containing protein 0.002 0.0148 0.1299
Brugia malayi AF-10 protein 0.002 0.0148 0.0407
Echinococcus multilocularis microtubule associated protein 2 0.0736 1 1
Onchocerca volvulus 0.0017 0.0106 0.0302
Brugia malayi PHD-finger family protein 0.0081 0.0979 0.2767
Schistosoma mansoni hypothetical protein 0.0039 0.0401 0.0401
Entamoeba histolytica cysteine proteinase, putative 0.0012 0.0026 0.0655
Loa Loa (eye worm) PHD-finger family protein 0.0065 0.0768 0.1693
Echinococcus granulosus geminin 0.0176 0.229 0.2287
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0039 0.0404 0.3171
Onchocerca volvulus 0.0087 0.107 0.3182
Brugia malayi nuclear hormone receptor 0.0021 0.0159 0.0439
Leishmania major GTP-binding protein, putative 0.0023 0.0187 0.1799
Brugia malayi Nuclear hormone receptor-like 1 0.0011 0.0021 0.0047
Loa Loa (eye worm) hypothetical protein 0.0012 0.0026 0.0049
Schistosoma mansoni nuclear hormone receptor 0.001 0.0004 0.0004
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0021 0.0153 0.1333
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0021 0.0159 0.0155
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0153 0.1333
Loa Loa (eye worm) hypothetical protein 0.0012 0.0026 0.0049
Echinococcus multilocularis lysine specific demethylase 6a 0.0036 0.0369 0.0364
Trypanosoma cruzi DNA polymerase kappa, putative 0.0021 0.0153 0.1333
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0023 0.0187 0.1676
Trichomonas vaginalis DNA helicase recq, putative 0.0014 0.0057 0.0091
Schistosoma mansoni methyl-cpg binding protein mbd 0.0054 0.0612 0.0612
Leishmania major cathepsin L-like protease 0.0066 0.0779 1
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0039 0.0404 0.0886
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0106 0.0238
Schistosoma mansoni hypothetical protein 0.0033 0.0326 0.0326
Schistosoma mansoni steroid hormone receptor ad4bp 0.0021 0.0159 0.0159
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0011 0.0021 0.0017
Echinococcus multilocularis lamin dm0 0.0087 0.107 0.1066
Echinococcus granulosus phd:f box containing protein 0.0036 0.0369 0.0364
Brugia malayi Probable ClpP-like protease 0.0086 0.1047 0.2959
Echinococcus multilocularis lamin 0.0087 0.107 0.1066
Brugia malayi Cathepsin L-like cysteine proteinase 0.0012 0.0026 0.0063
Loa Loa (eye worm) hypothetical protein 0.0021 0.0159 0.0343
Schistosoma mansoni bromodomain containing protein 0.0015 0.0077 0.0077
Trypanosoma cruzi cysteine peptidase, putative 0.0017 0.0106 0.0678
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0021 0.0159 0.0159
Trichomonas vaginalis ran, putative 0.0023 0.0187 0.0481
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0066 0.0779 1
Brugia malayi Nuclear hormone receptor-like 1 0.0011 0.0021 0.0047
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0021 0.0159 0.0155
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0021 0.0159 0.0155
Schistosoma mansoni ran 0.0023 0.0187 0.0187
Loa Loa (eye worm) hypothetical protein 0.013 0.1662 0.3675
Loa Loa (eye worm) hypothetical protein 0.0021 0.0159 0.0343
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0021 0.0159 0.0439
Leishmania major cathepsin L-like protease 0.0017 0.0106 0.0678
Schistosoma mansoni cpg binding protein 0.0039 0.0401 0.0401
Loa Loa (eye worm) hypothetical protein 0.0129 0.1647 0.3641
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0036 0.0369 0.3435
Onchocerca volvulus Protein ultraspiracle homolog 0.0021 0.0159 0.0462
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0106 0.0238
Echinococcus granulosus cathepsin l1 0.0017 0.0106 0.0101
Loa Loa (eye worm) hypothetical protein 0.0033 0.0326 0.0713
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0011 0.0013 0.0009
Trypanosoma brucei importin beta-1 subunit, putative 0.0032 0.0302 0.3392
Brugia malayi Cathepsin L-like precursor 0.0012 0.0026 0.0063
Echinococcus granulosus ecdysone induced protein 78C 0.0021 0.0159 0.0155
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.001 0.0004 0.0004
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0021 0.0159 0.0343
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0036 0.0369 0.4319
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0023 0.0187 0.086
Trypanosoma brucei DNA polymerase IV, putative 0.0021 0.0153 0.1333
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0086 0.1047 1
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0153 0.1333
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0033 0.0314 0.031
Brugia malayi Bromodomain containing protein 0.0122 0.154 0.4358
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0153 0.1333
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0044 0.0476 0.0472
Brugia malayi Pre-SET motif family protein 0.0223 0.2932 0.8306
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0153 0.1333
Trypanosoma cruzi cysteine peptidase, putative 0.0066 0.0779 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0106 0.0238
Echinococcus granulosus lamin dm0 0.0087 0.107 0.1066
Onchocerca volvulus 0.0033 0.0314 0.0924
Trypanosoma brucei ISWI complex protein 0.0049 0.0535 0.6623
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0039 0.0404 0.04
Brugia malayi Bromodomain containing protein 0.024 0.3169 0.8979
Loa Loa (eye worm) histone methyltransferase 0.0011 0.0014 0.0022
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0191 0.25 0.2497
Echinococcus granulosus cathepsin l cysteine peptidase 0.0017 0.0106 0.0101
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0021 0.0159 0.0155
Echinococcus granulosus methyl CpG binding domain protein 2 0.0054 0.0612 0.0607
Leishmania major cathepsin L-like protease 0.0017 0.0106 0.0678
Schistosoma mansoni jumonji/arid domain-containing protein 0.0145 0.1858 0.1858
Trypanosoma cruzi DNA polymerase kappa, putative 0.0021 0.0153 0.1333
Brugia malayi Intermediate filament tail domain containing protein 0.0087 0.107 0.3024
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0106 0.0238
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0026 0.0219 0.0579
Brugia malayi Cathepsin L-like precursor 0.0012 0.0026 0.0063
Trypanosoma brucei DNA polymerase kappa, putative 0.0014 0.0064 0.01
Schistosoma mansoni DNA polymerase eta 0.0021 0.0153 0.0153
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0011 0.0021 0.0021
Echinococcus multilocularis snurportin 1 0.0338 0.4515 0.4513
Echinococcus granulosus dna polymerase kappa 0.0021 0.0153 0.0149
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0033 0.0314 0.2906
Loa Loa (eye worm) hypothetical protein 0.0124 0.1567 0.3465
Echinococcus multilocularis peptidase Clp (S14 family) 0.0056 0.064 0.0636
Schistosoma mansoni hypothetical protein 0.0131 0.1667 0.1667
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0106 0.0238
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0066 0.0779 1
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0021 0.0159 0.0343
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0021 0.0159 0.0439
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0017 0.0106 0.1009
Brugia malayi Pre-SET motif family protein 0.0033 0.0314 0.0878
Toxoplasma gondii WD domain, G-beta repeat-containing protein 0.002 0.0148 0.1299
Brugia malayi hypothetical protein 0.0039 0.0401 0.1125
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0106 0.0238
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) 0.0056 0.064 1
Schistosoma mansoni hypothetical protein 0.0033 0.0326 0.0326
Schistosoma mansoni coup transcription factor 0.0021 0.0159 0.0159
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0049 0.0546 0.0542
Loa Loa (eye worm) hypothetical protein 0.0017 0.0106 0.0225
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0042 0.0447 0.0443
Loa Loa (eye worm) fibroinase 0.0017 0.0106 0.0225
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0106 0.0238
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0033 0.0326 0.0322
Schistosoma mansoni retinoic acid receptor RXR 0.0021 0.0159 0.0159
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0054 0.0612 0.0607
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0039 0.0404 0.5472
Brugia malayi cytoplasmic intermediate filament protein 0.0047 0.0511 0.1438
Trypanosoma cruzi DNA polymerase eta, putative 0.0021 0.0153 0.1333
Trypanosoma brucei DNA polymerase kappa, putative 0.0014 0.0064 0.01
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.0011 0.0013 0.0128
Schistosoma mansoni cathepsin F (C01 family) 0.0017 0.0106 0.0106
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0106 0.0238
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0011 0.0014 0.001
Schistosoma mansoni lamin 0.0087 0.107 0.107
Onchocerca volvulus 0.0017 0.0106 0.0302
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0011 0.0021 0.0037
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0021 0.0159 0.0439
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0017 0.0106 0.0225
Schistosoma mansoni hypothetical protein 0.0176 0.229 0.229
Echinococcus multilocularis ecdysone induced protein 78C 0.0021 0.0159 0.0155
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0033 0.0326 0.0322
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0017 0.0105 0.0881
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0153 0.1333
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0021 0.0159 0.0439
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0087 0.1059 0.1059
Brugia malayi jmjC domain containing protein 0.0266 0.3529 1
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0047 0.0511 0.1124
Loa Loa (eye worm) hypothetical protein 0.0012 0.0026 0.0049
Brugia malayi cathepsin L-like precursor 0.0012 0.0026 0.0063
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0021 0.0153 0.0153
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0031 0.0288 0.0284
Brugia malayi Steroid receptor seven-up type 2 0.0021 0.0159 0.0439
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0087 0.107 0.2363
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0021 0.0153 0.0149
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0106 0.0238
Schistosoma mansoni hypothetical protein 0.0033 0.0326 0.0326
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0023 0.0187 0.0182
Schistosoma mansoni cathepsin F (C01 family) 0.0012 0.0026 0.0026
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0042 0.0447 0.0443
Loa Loa (eye worm) ctsf protein 0.0017 0.0106 0.0225
Loa Loa (eye worm) hypothetical protein 0.0011 0.0013 0.002
Onchocerca volvulus 0.0017 0.0106 0.0302
Echinococcus multilocularis jumonji domain containing protein 0.0087 0.1065 0.1061
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0023 0.0187 0.1799
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0023 0.0187 0.0404
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0106 0.0238
Entamoeba histolytica hypothetical protein 0.0039 0.0401 0.9917
Entamoeba histolytica cysteine protease, putative 0.0017 0.0106 0.2614
Entamoeba histolytica cysteine proteinase, putative 0.0017 0.0106 0.2614
Schistosoma mansoni hypothetical protein 0.0063 0.0728 0.0728
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0066 0.0779 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0106 0.0238
Onchocerca volvulus Cathepsin F homolog 0.0017 0.0106 0.0302
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0021 0.0159 0.0159
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0033 0.0314 0.0314
Schistosoma mansoni nuclear hormone receptor 0.001 0.0004 0.0004
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0191 0.25 0.2497
Giardia lamblia PHD finger protein 15 0.0063 0.0728 1
Schistosoma mansoni nuclear receptor 0.001 0.0004 0.0004
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0106 0.0238
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0011 0.0013 0.0000000006488
Toxoplasma gondii exonuclease III APE 0.0039 0.0404 0.378
Schistosoma mansoni hypothetical protein 0.0176 0.229 0.229
Brugia malayi nuclear receptor NHR-88 0.0021 0.0159 0.0439
Leishmania major DNA polymerase kappa, putative 0.0021 0.0153 0.1333
Brugia malayi Cathepsin L-like precursor 0.0017 0.0106 0.0287
Leishmania major cathepsin L-like protease 0.0017 0.0106 0.0678
Echinococcus granulosus jumonji domain containing 1A 0.0036 0.0369 0.0364
Trypanosoma cruzi importin beta-1 subunit, putative 0.0026 0.0219 0.2251
Loa Loa (eye worm) hypothetical protein 0.0021 0.0159 0.0343
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0066 0.0779 1
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0073 0.0876 0.0872
Trichomonas vaginalis DNA helicase recq, putative 0.0026 0.0223 0.059
Brugia malayi Cathepsin L-like precursor 0.0017 0.0106 0.0287
Brugia malayi Cathepsin L-like precursor 0.0017 0.0106 0.0287
Echinococcus granulosus importin subunit beta 1 0.0032 0.0302 0.0297
Trypanosoma cruzi major cysteine proteinase, putative 0.0052 0.0583 0.7295
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0153 0.1333
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0021 0.0159 0.0439
Leishmania major hypothetical protein, conserved 0.0036 0.0369 0.4319
Loa Loa (eye worm) jmjC domain-containing protein 0.0145 0.1858 0.4109
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0039 0.0404 0.04
Leishmania major DNA polymerase eta, putative 0.0021 0.0153 0.1333
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0021 0.0153 0.038
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0021 0.0159 0.0343
Trichomonas vaginalis ap endonuclease, putative 0.0039 0.0404 0.1135
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) 0.0056 0.064 1
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0036 0.0369 0.4319
Entamoeba histolytica hypothetical protein 0.0039 0.0401 0.9917
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0039 0.0404 0.4813
Trypanosoma cruzi ISWI complex protein 0.0049 0.0535 0.6623
Leishmania major cysteine peptidase A (CPA) 0.0017 0.0106 0.0678
Echinococcus multilocularis cysteine protease 0.0017 0.0106 0.0101
Toxoplasma gondii PHD-finger domain-containing protein 0.0063 0.0728 0.6908
Echinococcus granulosus FTZ F1 alpha 0.0021 0.0159 0.0155
Trichomonas vaginalis ap endonuclease, putative 0.0039 0.0404 0.1135
Onchocerca volvulus 0.0087 0.107 0.3182
Brugia malayi jmjC domain containing protein 0.0036 0.0369 0.1033
Trypanosoma cruzi cruzipain precursor, putative 0.0066 0.0779 1
Echinococcus multilocularis lysine specific demethylase 5A 0.0137 0.175 0.1747
Plasmodium vivax hypothetical protein, conserved 0.0063 0.0728 0.6605
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.0131 0.1667 0.1663
Loa Loa (eye worm) steroid hormone receptor 0.0021 0.0159 0.0343
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.003 0.0273 0.1778
Loa Loa (eye worm) hypothetical protein 0.0021 0.0159 0.0343
Wolbachia endosymbiont of Brugia malayi ATP-dependent Clp protease proteolytic subunit 0.0086 0.1047 1
Toxoplasma gondii hypothetical protein 0.003 0.0273 0.2511
Schistosoma mansoni hypothetical protein 0.0065 0.0768 0.0768
Loa Loa (eye worm) hypothetical protein 0.0063 0.0728 0.1603
Echinococcus granulosus lysine specific demethylase 5A 0.0145 0.1858 0.1854
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0023 0.0187 0.2426
Onchocerca volvulus 0.0021 0.0159 0.0462
Trichomonas vaginalis DNA polymerase eta, putative 0.0021 0.0153 0.038
Schistosoma mansoni zinc finger protein 0.0049 0.0535 0.0535
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0049 0.0546 0.0546
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0266 0.3529 0.3526
Loa Loa (eye worm) hypothetical protein 0.0011 0.0021 0.0037
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0153 0.1333
Echinococcus granulosus fetal alzheimer antigen falz 0.0073 0.0876 0.0872
Entamoeba histolytica cysteine proteinase, putative 0.0017 0.0106 0.2614
Loa Loa (eye worm) hypothetical protein 0.0021 0.0153 0.0329
Trypanosoma brucei unspecified product 0.0014 0.0064 0.01
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0021 0.0159 0.0439
Schistosoma mansoni ran 0.0023 0.0187 0.0187
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0039 0.0404 0.4813
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) 0.0056 0.064 0.4744
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0021 0.0159 0.0439
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0114 0.1437 0.1433
Echinococcus multilocularis jumonji domain containing 1A 0.0036 0.0369 0.0364
Loa Loa (eye worm) hypothetical protein 0.0086 0.1047 0.2312
Echinococcus granulosus peregrin 0.007 0.0831 0.0827
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0036 0.0369 0.3435
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0033 0.0326 0.0913
Onchocerca volvulus 0.0031 0.0293 0.0862
Schistosoma mansoni importin beta-1 0.0032 0.0302 0.0302
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0106 0.132 0.2917
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.002 0.0148 0.126
Trypanosoma brucei DNA polymerase kappa, putative 0.0014 0.0064 0.01
Onchocerca volvulus 0.0017 0.0106 0.0302
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0011 0.0013 0.002
Schistosoma mansoni hypothetical protein 0.002 0.0148 0.0148
Schistosoma mansoni intermediate filament proteins 0.0087 0.107 0.107
Schistosoma mansoni nuclear hormone receptor 0.0021 0.0159 0.0159
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.001 0.0004 0.0004
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0067 0.0788 0.0788
Onchocerca volvulus Bile acid receptor homolog 0.0021 0.0159 0.0462
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0061 0.07 0.8903
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.002 0.0148 0.126
Echinococcus multilocularis GPCR, family 2 0.0033 0.0326 0.0322
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0021 0.0159 0.0439
Echinococcus granulosus peptidase Clp S14 family 0.0056 0.064 0.0636
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0039 0.0404 1
Onchocerca volvulus 0.0017 0.0106 0.0302
Entamoeba histolytica hypothetical protein 0.0039 0.0401 0.9917
Loa Loa (eye worm) hypothetical protein 0.0011 0.0021 0.0037
Trypanosoma cruzi DNA polymerase kappa, putative 0.0021 0.0153 0.1333
Schistosoma mansoni phosphatidylserine receptor 0.0036 0.0369 0.0369
Echinococcus granulosus GTP binding nuclear protein Ran 0.0023 0.0187 0.0182
Brugia malayi ImpB/MucB/SamB family protein 0.0021 0.0153 0.0422
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0017 0.0106 0.0238
Echinococcus granulosus histone lysine methyltransferase setb 0.0087 0.1059 0.1055
Plasmodium falciparum JmjC domain-containing protein, putative 0.0036 0.0369 0.3519
Trypanosoma cruzi cysteine peptidase, putative 0.0066 0.0779 1
Leishmania major importin beta-1 subunit, putative 0.0026 0.0219 0.2251
Onchocerca volvulus Cathepsin L homolog 0.0017 0.0106 0.0302
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0106 0.0238
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0021 0.0159 0.0439
Echinococcus multilocularis PHD finger protein rhinoceros 0.0063 0.0728 0.0724
Loa Loa (eye worm) hypothetical protein 0.0224 0.2958 0.6547
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0021 0.0159 0.0343
Loa Loa (eye worm) jmjC domain-containing protein 0.0129 0.1645 0.3637
Echinococcus multilocularis cathepsin L cysteine protease 0.0017 0.0106 0.0101
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0023 0.0187 0.1799
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0021 0.0159 0.0159
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0021 0.0159 0.0155
Toxoplasma gondii cathepsin CPL 0.0017 0.0106 0.0892
Schistosoma mansoni thyroid hormone receptor 0.0152 0.196 0.196
Brugia malayi jmjC domain containing protein 0.0036 0.0369 0.1033
Echinococcus multilocularis FTZ F1 alpha 0.0021 0.0159 0.0155
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0049 0.0546 0.0542
Schistosoma mansoni cpg binding protein 0.0031 0.0293 0.0293
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0033 0.0326 0.0322
Schistosoma mansoni phd/f-box containing protein 0.0036 0.0369 0.0369
Brugia malayi jmjC domain containing protein 0.0036 0.0369 0.1033
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0021 0.0159 0.0159
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0021 0.0159 0.0155
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0021 0.0159 0.0343
Loa Loa (eye worm) PHD-finger family protein 0.0063 0.0728 0.1603
Echinococcus multilocularis cathepsin L cysteine protease 0.0017 0.0106 0.0101
Onchocerca volvulus Alhambra homolog 0.0063 0.0728 0.2159
Plasmodium vivax hypothetical protein, conserved 0.0022 0.0174 0.0723
Entamoeba histolytica hypothetical protein 0.0026 0.0219 0.5425
Loa Loa (eye worm) jmjC domain-containing protein 0.0036 0.0369 0.0807
Toxoplasma gondii histone lysine methyltransferase SET1 0.0067 0.0794 0.7554
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0021 0.0159 0.0155
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0036 0.0369 0.4319
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0106 0.132 0.3733
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0066 0.0779 1
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0021 0.0159 0.0439
Schistosoma mansoni zinc finger protein 0.0064 0.0746 0.0746
Brugia malayi jmjC domain containing protein 0.0036 0.0369 0.1033
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0049 0.0546 0.0542
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0021 0.0159 0.0462
Plasmodium falciparum importin beta, putative 0.0032 0.0302 0.288
Loa Loa (eye worm) hypothetical protein 0.0011 0.0021 0.0037
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0021 0.0159 0.0155
Toxoplasma gondii HEAT repeat-containing protein 0.0032 0.0302 0.2788
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0017 0.0106 0.0101
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0044 0.0476 0.0472
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0039 0.0404 0.5155
Brugia malayi exodeoxyribonuclease III family protein 0.0039 0.0404 0.1134
Loa Loa (eye worm) hypothetical protein 0.0137 0.1755 0.388
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0106 0.0238
Schistosoma mansoni thyroid hormone receptor 0.0152 0.196 0.196
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0039 0.0401 0.0397
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0011 0.0013 0.0009
Echinococcus granulosus dna polymerase eta 0.0021 0.0153 0.0149
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0066 0.0779 1
Schistosoma mansoni hypothetical protein 0.0049 0.0535 0.0535
Loa Loa (eye worm) hypothetical protein 0.0087 0.107 0.2363
Loa Loa (eye worm) jmjC domain-containing protein 0.0036 0.0369 0.0807
Loa Loa (eye worm) hypothetical protein 0.0011 0.0021 0.0037
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0011 0.0013 0.0009
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0021 0.0159 0.0155
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.003 0.0273 0.2607
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0011 0.0013 0.0026
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0011 0.0021 0.0021
Brugia malayi PHD-finger family protein 0.0028 0.0256 0.0713
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0021 0.0159 0.0155
Brugia malayi intermediate filament protein 0.0087 0.107 0.3024
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0023 0.0187 0.1782
Loa Loa (eye worm) hypothetical protein 0.0015 0.0077 0.0162
Loa Loa (eye worm) hypothetical protein 0.0122 0.1543 0.3412
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0039 0.0401 0.0397
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0049 0.0546 0.0542
Schistosoma mansoni hypothetical protein 0.0338 0.4515 0.4515
Echinococcus granulosus lysine specific demethylase 6a 0.0036 0.0369 0.0364
Brugia malayi ImpB/MucB/SamB family protein 0.0021 0.0153 0.0422
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0011 0.0013 0.0009
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0023 0.0187 0.1799
Loa Loa (eye worm) intermediate filament protein 0.0087 0.107 0.2363
Trypanosoma brucei importin beta-1 subunit, putative 0.0032 0.0302 0.3392
Brugia malayi PHD-finger family protein 0.0063 0.0728 0.2052
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0106 0.0238

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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