Detailed information for compound 740689

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 353.155 | Formula: C14H12INO2
  • H donors: 2 H acceptors: 2 LogP: 3.53 Rotable bonds: 2
    Rule of 5 violations (Lipinski): 1
  • SMILES: Cc1ccc(cc1I)N=Cc1cccc(c1O)O
  • InChi: 1S/C14H12INO2/c1-9-5-6-11(7-12(9)15)16-8-10-3-2-4-13(17)14(10)18/h2-8,17-18H,1H3/b16-8+
  • InChiKey: IKWDAGDLWHNZGQ-LZYBPNLTSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi dihydrofolate reductase family protein 0.0374 0.4663 1
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0024 0.0094 0.0018
Echinococcus multilocularis carnitine O palmitoyltransferase 2 0.0024 0.0086 0.0062
Echinococcus granulosus jumonji domain containing 1A 0.0024 0.0094 0.015
Brugia malayi Bromodomain containing protein 0.003 0.0175 0.0236
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0126 0.0176
Loa Loa (eye worm) hypothetical protein 0.0131 0.1486 0.3187
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0282 0.3462 1
Loa Loa (eye worm) hypothetical protein 0.0068 0.0669 0.1434
Echinococcus granulosus jumonji domain containing protein 0.0039 0.0289 0.0571
Loa Loa (eye worm) hypothetical protein 0.0063 0.0605 0.1298
Loa Loa (eye worm) hypothetical protein 0.003 0.0163 0.035
Schistosoma mansoni jumonji/arid domain-containing protein 0.0093 0.0988 0.2077
Schistosoma mansoni chromobox protein 0.0067 0.0656 0.1361
Echinococcus multilocularis jumonji domain containing protein 0.0039 0.0289 0.0265
Echinococcus multilocularis geminin 0.0164 0.1913 0.1894
Schistosoma mansoni acetylcholinesterase 0.0022 0.0066 0.0091
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0045 0.0369 0.0743
Schistosoma mansoni choline o-acyltransferase 0.0024 0.0086 0.0133
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0041 0.0307 0.0893
Schistosoma mansoni bifunctional dihydrofolate reductase-thymidylate synthase 0.0104 0.1132 0.2388
Toxoplasma gondii bifunctional dihydrofolate reductase-thymidylate synthase 0.0273 0.3341 1
Loa Loa (eye worm) PHD-finger family protein 0.002 0.0037 0.008
Schistosoma mansoni hypothetical protein 0.0028 0.0145 0.026
Echinococcus granulosus carnitine O palmitoyltransferase 2 0.0024 0.0086 0.0133
Trichomonas vaginalis chromobox protein, putative 0.0041 0.0307 0.071
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0031 0.0182 0.0341
Loa Loa (eye worm) hypothetical protein 0.0022 0.0066 0.0142
Loa Loa (eye worm) hypothetical protein 0.0024 0.0094 0.0201
Brugia malayi PHD-finger family protein 0.0024 0.0091 0.0055
Trypanosoma cruzi choline/carnitine O-acyltransferase, putative 0.0129 0.1459 0.3156
Brugia malayi Choline/Carnitine o-acyltransferase family protein 0.0024 0.0086 0.0043
Leishmania major pteridine reductase 1 0.019 0.226 0.4995
Loa Loa (eye worm) hypothetical protein 0.0022 0.0066 0.0142
Brugia malayi Latrophilin receptor protein 2 0.0031 0.0182 0.0252
Schistosoma mansoni dihydrofolate reductase 0.0374 0.4663 1
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0035 0.023 0.0207
Loa Loa (eye worm) hypothetical protein 0.0067 0.0652 0.1398
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0028 0.014 0.0249
Trichomonas vaginalis glucosylceramidase, putative 0.017 0.199 0.5665
Loa Loa (eye worm) jmjC domain-containing protein 0.0093 0.0988 0.2118
Echinococcus granulosus neuroligin 0.0022 0.0066 0.0091
Loa Loa (eye worm) dihydrofolate reductase 0.0374 0.4663 1
Loa Loa (eye worm) hypothetical protein 0.0357 0.4438 0.9517
Echinococcus multilocularis carnitine O palmitoyltransferase 1, liver 0.0129 0.1459 0.1439
Schistosoma mansoni hypothetical protein 0.0164 0.1913 0.4073
Echinococcus granulosus tar DNA binding protein 0.0061 0.0576 0.1189
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0061 0.0576 0.1235
Brugia malayi thymidylate synthase 0.0104 0.1132 0.2318
Brugia malayi PHD-finger family protein 0.0028 0.0145 0.0171
Schistosoma mansoni chromobox protein 0.0067 0.0656 0.1361
Echinococcus granulosus dihydrofolate reductase 0.0374 0.4663 1
Mycobacterium tuberculosis Probable thymidylate synthase ThyA (ts) (TSASE) 0.0104 0.1132 0.2318
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0031 0.0182 0.0158
Onchocerca volvulus 0.0024 0.0086 0.0073
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0058 0.053 0.0507
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0026 0.0118 0.0202
Schistosoma mansoni tar DNA-binding protein 0.0061 0.0576 0.1189
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0126 0.0176
Echinococcus granulosus thymidylate synthase 0.0104 0.1132 0.2388
Schistosoma mansoni jumonji/arid domain-containing protein 0.0093 0.0988 0.2077
Loa Loa (eye worm) MH2 domain-containing protein 0.0115 0.1282 0.275
Echinococcus multilocularis dihydrofolate reductase 0.0374 0.4663 0.4651
Schistosoma mansoni hypothetical protein 0.0031 0.0182 0.0341
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0282 0.3462 1
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0022 0.0066 0.0091
Brugia malayi ERG2 and Sigma1 receptor like protein 0.0357 0.4438 0.951
Plasmodium vivax hypothetical protein, conserved 0.0028 0.0145 0.0158
Giardia lamblia Fructose-bisphosphate aldolase 0.0282 0.3462 1
Loa Loa (eye worm) hypothetical protein 0.0045 0.0369 0.079
Echinococcus granulosus PHD finger protein rhinoceros 0.0028 0.0145 0.026
Onchocerca volvulus Alhambra homolog 0.0028 0.0145 0.0292
Leishmania major hypothetical protein, conserved 0.0024 0.0094 0.0018
Trichomonas vaginalis glucosylceramidase, putative 0.0179 0.2109 0.6016
Schistosoma mansoni gliotactin 0.0022 0.0066 0.0091
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.027 0.0599
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0138 0.1577 0.3287
Echinococcus multilocularis PHD finger protein rhinoceros 0.0028 0.0145 0.0121
Brugia malayi RNA binding protein 0.0061 0.0576 0.1109
Plasmodium vivax SET domain protein, putative 0.0029 0.0154 0.0185
Trypanosoma cruzi C-8 sterol isomerase, putative 0.0357 0.4438 1
Echinococcus granulosus histone lysine methyltransferase setb 0.0045 0.0369 0.0743
Trichomonas vaginalis glucosylceramidase, putative 0.0258 0.3149 0.908
Trypanosoma cruzi dihydrofolate reductase-thymidylate synthase, putative 0.0049 0.0422 0.0772
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0149 0.1722 0.1702
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0258 0.3149 0.6753
Echinococcus multilocularis chromobox protein 1 0.0067 0.0656 0.0633
Mycobacterium leprae DIHYDROFOLATE REDUCTASE DFRA (DHFR) (TETRAHYDROFOLATE DEHYDROGENASE) 0.0374 0.4663 1
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.004 0.0297 0.0589
Loa Loa (eye worm) hypothetical protein 0.0131 0.1486 0.3187
Echinococcus granulosus GPCR family 2 0.0031 0.0182 0.0341
Echinococcus multilocularis phd:f box containing protein 0.0024 0.0094 0.007
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0029 0.0154 0.0279
Trichomonas vaginalis chromobox protein, putative 0.0041 0.0307 0.071
Echinococcus granulosus BC026374 protein S09 family 0.0022 0.0066 0.0091
Schistosoma mansoni choline o-acyltransferase 0.0024 0.0086 0.0133
Echinococcus multilocularis para nitrobenzyl esterase 0.0022 0.0066 0.0042
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0022 0.0061 0.0037
Schistosoma mansoni tar DNA-binding protein 0.0061 0.0576 0.1189
Loa Loa (eye worm) hypothetical protein 0.0028 0.0145 0.0311
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0282 0.3462 0.5
Trichomonas vaginalis glucosylceramidase, putative 0.017 0.199 0.5665
Leishmania major choline/Carnitine o-acyltransferase-like protein 0.0129 0.1459 0.3156
Loa Loa (eye worm) hypothetical protein 0.0183 0.216 0.4631
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0258 0.3149 0.6706
Loa Loa (eye worm) heterochromatin protein 1 0.0067 0.0656 0.1406
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0098 0.1057 0.2155
Brugia malayi latrophilin 2 splice variant baaae 0.0067 0.0652 0.1274
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0031 0.0182 0.0252
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0201 0.2401 0.5149
Loa Loa (eye worm) choline/Carnitine O-acyltransferase 0.0024 0.0086 0.0184
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.027 0.0599
Loa Loa (eye worm) thymidylate synthase 0.0104 0.1132 0.2427
Brugia malayi jmjC domain containing protein 0.0024 0.0094 0.006
Echinococcus granulosus JmjC domain containing protein 4 0.0024 0.0094 0.015
Brugia malayi Bromodomain containing protein 0.0072 0.0723 0.1428
Loa Loa (eye worm) RNA binding protein 0.0061 0.0576 0.1235
Echinococcus multilocularis lysine specific demethylase 5A 0.0091 0.0964 0.0942
Brugia malayi Choline/Carnitine o-acyltransferase family protein 0.0129 0.1459 0.3031
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0024 0.0094 0.0018
Onchocerca volvulus 0.0024 0.0086 0.0073
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0282 0.3462 1
Echinococcus granulosus phd:f box containing protein 0.0024 0.0094 0.015
Loa Loa (eye worm) jmjC domain-containing protein 0.0024 0.0094 0.0201
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0282 0.3462 1
Brugia malayi Carboxylesterase family protein 0.0131 0.1486 0.3089
Echinococcus multilocularis chromobox protein 1 0.0067 0.0656 0.0633
Loa Loa (eye worm) hypothetical protein 0.0037 0.0261 0.056
Trichomonas vaginalis glucosylceramidase, putative 0.0258 0.3149 0.908
Schistosoma mansoni tar DNA-binding protein 0.0061 0.0576 0.1189
Onchocerca volvulus Glucosylceramidase homolog 0.017 0.199 0.7132
Brugia malayi Pre-SET motif family protein 0.0029 0.0154 0.019
Trichomonas vaginalis chromobox protein, putative 0.0067 0.0656 0.1736
Trichomonas vaginalis conserved hypothetical protein 0.0049 0.0422 0.1047
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0022 0.0066 0.0091
Loa Loa (eye worm) hypothetical protein 0.0038 0.027 0.0578
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0098 0.1057 0.2266
Treponema pallidum fructose-bisphosphate aldolase 0.0282 0.3462 0.5
Loa Loa (eye worm) TAR-binding protein 0.0061 0.0576 0.1235
Echinococcus granulosus acetylcholinesterase 0.0131 0.1486 0.3152
Echinococcus multilocularis neuroligin 0.0022 0.0066 0.0042
Loa Loa (eye worm) jmjC domain-containing protein 0.0024 0.0094 0.0201
Plasmodium vivax bifunctional dihydrofolate reductase-thymidylate synthase, putative 0.0273 0.3341 1
Echinococcus granulosus acetylcholinesterase 0.0131 0.1486 0.3152
Onchocerca volvulus 0.0104 0.1132 0.3951
Trypanosoma brucei pteridine reductase 1 0.0188 0.2227 0.492
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0138 0.1577 0.3287
Echinococcus multilocularis acetylcholinesterase 0.0131 0.1486 0.1466
Echinococcus multilocularis BC026374 protein (S09 family) 0.0022 0.0066 0.0042
Loa Loa (eye worm) carboxylesterase 0.0131 0.1486 0.3187
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0282 0.3462 1
Schistosoma mansoni hypothetical protein 0.0031 0.0182 0.0341
Loa Loa (eye worm) acetylcholinesterase 1 0.0131 0.1486 0.3187
Brugia malayi TAR-binding protein 0.0061 0.0576 0.1109
Plasmodium falciparum phd finger protein, putative 0.0028 0.0145 0.0158
Loa Loa (eye worm) latrophilin receptor protein 2 0.0031 0.0182 0.039
Echinococcus multilocularis choline O acetyltransferase 0.0024 0.0086 0.0062
Echinococcus granulosus geminin 0.0164 0.1913 0.4073
Trichomonas vaginalis glucosylceramidase, putative 0.0258 0.3149 0.908
Brugia malayi Carboxylesterase family protein 0.0131 0.1486 0.3089
Brugia malayi Bromodomain containing protein 0.0037 0.026 0.0422
Schistosoma mansoni bromodomain containing protein 0.0061 0.0575 0.1188
Trichomonas vaginalis glucosylceramidase, putative 0.017 0.199 0.5665
Trypanosoma brucei C-8 sterol isomerase, putative 0.0357 0.4438 1
Echinococcus granulosus chromobox protein 1 0.0067 0.0656 0.1361
Onchocerca volvulus 0.0024 0.0086 0.0073
Brugia malayi Heterochromatin protein 1 0.0067 0.0656 0.1282
Loa Loa (eye worm) hypothetical protein 0.0024 0.0094 0.0201
Brugia malayi Choline O-acetyltransferase 0.0024 0.0086 0.0043
Loa Loa (eye worm) carnitine O-palmitoyltransferase I isoform 0.0024 0.0086 0.0184
Loa Loa (eye worm) hypothetical protein 0.0024 0.0086 0.0184
Loa Loa (eye worm) jmjC domain-containing protein 0.0058 0.0536 0.115
Toxoplasma gondii PHD-finger domain-containing protein 0.0028 0.0145 0.0158
Schistosoma mansoni tar DNA-binding protein 0.0061 0.0576 0.1189
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0028 0.0145 0.026
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0282 0.3462 1
Schistosoma mansoni hypothetical protein 0.002 0.0037 0.0029
Schistosoma mansoni BC026374 protein (S09 family) 0.0022 0.0066 0.0091
Trichomonas vaginalis glucosylceramidase, putative 0.0258 0.3149 0.908
Trypanosoma cruzi choline/carnitine O-acyltransferase, putative 0.0129 0.1459 0.3156
Loa Loa (eye worm) hypothetical protein 0.0039 0.0291 0.0624
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0029 0.0154 0.013
Echinococcus multilocularis lysine specific demethylase 6a 0.0024 0.0094 0.007
Echinococcus multilocularis tar DNA binding protein 0.0061 0.0576 0.0553
Brugia malayi Choline O-acetyltransferase 0.0024 0.0086 0.0043
Trichomonas vaginalis glucosylceramidase, putative 0.017 0.199 0.5665
Brugia malayi Choline/Carnitine o-acyltransferase family protein 0.0024 0.0086 0.0043
Echinococcus granulosus chromobox protein 1 0.0067 0.0656 0.1361
Echinococcus granulosus choline O acetyltransferase 0.0024 0.0086 0.0133
Mycobacterium ulcerans dihydrofolate reductase DfrA 0.0374 0.4663 1
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0022 0.0061 0.0081
Brugia malayi Calcitonin receptor-like protein seb-1 0.0098 0.1057 0.2155
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0282 0.3462 1
Loa Loa (eye worm) choline O-acetyltransferase 0.0024 0.0086 0.0184
Brugia malayi chromobox protein homolog 3 0.0038 0.027 0.0443
Loa Loa (eye worm) hypothetical protein 0.0031 0.0182 0.039
Loa Loa (eye worm) jmjC domain-containing protein 0.0024 0.0094 0.0201
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0029 0.0154 0.0185
Schistosoma mansoni hypothetical protein 0.0164 0.1913 0.4073
Schistosoma mansoni neuroligin 3 (S09 family) 0.0022 0.0066 0.0091
Loa Loa (eye worm) hypothetical protein 0.0129 0.1459 0.3129
Brugia malayi hypothetical protein 0.0049 0.0422 0.0774
Brugia malayi jmjC domain containing protein 0.0093 0.0988 0.2005
Loa Loa (eye worm) PHD-finger family protein 0.0028 0.0145 0.0311
Echinococcus granulosus peregrin 0.003 0.0175 0.0325
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0045 0.0369 0.0345
Onchocerca volvulus 0.0229 0.2763 1
Trypanosoma brucei dihydrofolate reductase-thymidylate synthase 0.0273 0.3341 0.7479
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0035 0.023 0.0444
Brugia malayi jmjC domain containing protein 0.0024 0.0094 0.006
Trichomonas vaginalis glucosylceramidase, putative 0.017 0.199 0.5665
Brugia malayi jmjC domain containing protein 0.0024 0.0094 0.006
Schistosoma mansoni phosphatidylserine receptor 0.0024 0.0094 0.015
Brugia malayi Pre-SET motif family protein 0.0201 0.2401 0.5079
Loa Loa (eye worm) hypothetical protein 0.0022 0.0066 0.0142
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0038 0.027 0.0755
Mycobacterium ulcerans thymidylate synthase 0.0104 0.1132 0.2318
Loa Loa (eye worm) hypothetical protein 0.0022 0.0066 0.0142
Echinococcus multilocularis jumonji domain containing 1A 0.0024 0.0094 0.007
Trichomonas vaginalis glucosylceramidase, putative 0.017 0.199 0.5665
Echinococcus multilocularis peregrin 0.003 0.0175 0.0151
Echinococcus granulosus carboxylesterase 5A 0.0131 0.1486 0.3152
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0031 0.0182 0.0158
Leishmania major dihydrofolate reductase-thymidylate synthase 0.0273 0.3341 0.7479
Echinococcus multilocularis acetylcholinesterase 0.0131 0.1486 0.1466
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0282 0.3462 0.5
Echinococcus multilocularis carboxylesterase 5A 0.0131 0.1486 0.1466
Mycobacterium tuberculosis Dihydrofolate reductase DfrA (DHFR) (tetrahydrofolate dehydrogenase) 0.0374 0.4663 1
Onchocerca volvulus 0.003 0.0163 0.036
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0045 0.0369 0.0743
Leishmania major C-8 sterol isomerase-like protein 0.0357 0.4438 1
Trichomonas vaginalis glucosylceramidase, putative 0.0179 0.2109 0.6016
Echinococcus granulosus family S9 non peptidase ue S09 family 0.0022 0.0066 0.0091
Trichomonas vaginalis chromobox protein, putative 0.0067 0.0656 0.1736
Mycobacterium tuberculosis Hypothetical protein 0.0049 0.0422 0.0774
Loa Loa (eye worm) hypothetical protein 0.0022 0.0066 0.0142
Brugia malayi jmjC domain containing protein 0.0024 0.0094 0.006
Echinococcus granulosus para nitrobenzyl esterase 0.0022 0.0066 0.0091
Loa Loa (eye worm) hypothetical protein 0.0098 0.1057 0.2266
Loa Loa (eye worm) carboxylesterase 0.0022 0.0066 0.0142
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0031 0.0182 0.0341
Echinococcus multilocularis thymidylate synthase 0.0104 0.1132 0.111
Echinococcus multilocularis GPCR, family 2 0.0031 0.0182 0.0158
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0149 0.1722 0.3661
Onchocerca volvulus 0.0024 0.0086 0.0073
Schistosoma mansoni tar DNA-binding protein 0.0061 0.0576 0.1189
Loa Loa (eye worm) hypothetical protein 0.0022 0.0066 0.0142
Brugia malayi MH2 domain containing protein 0.0115 0.1282 0.2646
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0138 0.1577 0.1261
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0131 0.1486 0.3152
Loa Loa (eye worm) carboxylesterase 0.0022 0.0066 0.0142
Loa Loa (eye worm) hypothetical protein 0.0041 0.0315 0.0675
Trypanosoma cruzi dihydrofolate reductase-thymidylate synthase 0.0273 0.3341 0.7479
Schistosoma mansoni hypothetical protein 0.0067 0.0652 0.1353
Trichomonas vaginalis glucosylceramidase, putative 0.0258 0.3149 0.908
Toxoplasma gondii PHD-finger domain-containing protein 0.0028 0.0145 0.0158
Brugia malayi RNA recognition motif domain containing protein 0.0061 0.0576 0.1109
Loa Loa (eye worm) transcription factor SMAD2 0.0115 0.1282 0.275
Trichomonas vaginalis set domain proteins, putative 0.0229 0.2763 0.7943
Echinococcus granulosus fetal alzheimer antigen falz 0.0022 0.0061 0.0081
Echinococcus granulosus lysine specific demethylase 6a 0.0024 0.0094 0.015
Schistosoma mansoni protein phosphatase 2C 0.0024 0.0094 0.015
Onchocerca volvulus 0.004 0.0297 0.0857
Chlamydia trachomatis dihydrofolate reductase 0.0374 0.4663 0.5
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0022 0.0066 0.0091
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0058 0.053 0.109
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0026 0.0118 0.0094
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0024 0.0094 0.015
Echinococcus granulosus lysine specific demethylase 5A 0.0093 0.0988 0.2077
Brugia malayi jmjC domain containing protein 0.0149 0.1722 0.3603
Plasmodium falciparum bifunctional dihydrofolate reductase-thymidylate synthase 0.0273 0.3341 1
Echinococcus multilocularis JmjC domain containing protein 4 0.0024 0.0094 0.007
Echinococcus granulosus carnitine O palmitoyltransferase 1 liver 0.0129 0.1459 0.3094
Brugia malayi Dihydrofolate reductase 0.0374 0.4663 1
Schistosoma mansoni jumonji domain containing protein 0.0024 0.0094 0.015
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0282 0.3462 1
Trichomonas vaginalis glucosylceramidase, putative 0.0258 0.3149 0.908
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0024 0.0094 0.0018
Schistosoma mansoni jumonji domain containing protein 0.013 0.1475 0.3128
Schistosoma mansoni hypothetical protein 0.0031 0.0182 0.0341
Echinococcus multilocularis family S9 non peptidase ue (S09 family) 0.0022 0.0066 0.0042
Schistosoma mansoni phd/f-box containing protein 0.0024 0.0094 0.015
Schistosoma mansoni hypothetical protein 0.0031 0.0182 0.0341
Trichomonas vaginalis glucosylceramidase, putative 0.017 0.199 0.5665
Loa Loa (eye worm) hypothetical protein 0.0022 0.0066 0.0142

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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