Detailed information for compound 74262

Basic information

Technical information
  • TDR Targets ID: 74262
  • Name: 6-methoxy-2-[(4-methoxy-3,5-dimethylpyridin-2 -yl)methylsulfanyl]-1H-benzimidazole
  • MW: 329.417 | Formula: C17H19N3O2S
  • H donors: 1 H acceptors: 2 LogP: 3.46 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: COc1ccc2c(c1)[nH]c(n2)SCc1ncc(c(c1C)OC)C
  • InChi: 1S/C17H19N3O2S/c1-10-8-18-15(11(2)16(10)22-4)9-23-17-19-13-6-5-12(21-3)7-14(13)20-17/h5-8H,9H2,1-4H3,(H,19,20)
  • InChiKey: XURCIPRUUASYLR-UHFFFAOYSA-N  

Network

Hover on a compound node to display the structore

Synonyms

  • 6-methoxy-2-[(4-methoxy-3,5-dimethyl-2-pyridyl)methylsulfanyl]-1H-benzimidazole
  • 6-methoxy-2-[(4-methoxy-3,5-dimethyl-2-pyridyl)methylthio]-1H-benzimidazole
  • 6-methoxy-2-[(4-methoxy-3,5-dimethyl-pyridin-2-yl)methylsulfanyl]-1H-benzimidazole
  • omeprazole sulfide
  • 73590-85-9
  • 1H-Benzimidazole, 5-methoxy-2-(((4-methoxy-3,5-dimethyl-2-pyridinyl)methyl)thio)-
  • 5-Methoxy-2-(((4-methoxy-3,5-dimethyl-2-pyridyl)methyl)thio)benzimidazol
  • 5-Methoxy-2-(((4-methoxy-3,5-dimethyl-2-pyridyl)methyl)thio)benzimidazole
  • Ufiprazol [Spanish]
  • Ufiprazole [INN]
  • Ufiprazolum [Latin]

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens bombesin-like receptor 3 Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Echinococcus granulosus pyroglutamylated rfamide peptide receptor bombesin-like receptor 3 399 aa 375 aa 21.1 %

Obtained from network model

Ranking Plot


Putative Targets List


Species Potential target Raw Global Species
Trypanosoma cruzi Calcium ATPase SERCA-like 0.0089 0.0337 0.0598
Schistosoma mansoni Na+/K+ transporting ATPase subunit alpha 0.0066 0.0234 0.0784
Onchocerca volvulus 0.0026 0.0058 0.0602
Entamoeba histolytica cysteine protease, putative 0.0039 0.0117 0.1989
Onchocerca volvulus 0.0034 0.0092 0.0951
Plasmodium vivax cyclic nucleotide phosphodiesterase, putative 0.0058 0.0198 0.5029
Toxoplasma gondii sarco/endoplasmic reticulum Ca2+-ATPase 0.0089 0.0337 0.1211
Echinococcus granulosus chromobox protein 1 0.0148 0.06 0.2009
Schistosoma mansoni copper ABC transporter ATPase 0.0021 0.0034 0.0114
Trypanosoma brucei 3', 5'-cyclic nucleotide phosphodiesterase, putative 0.0058 0.0198 0.335
Schistosoma mansoni DNA helicase recq1 0.0018 0.0024 0.0079
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0022 0.0227
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.0058 0.0198 0.2057
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0058 0.0198 0.2057
Echinococcus multilocularis cathepsin L 0.0018 0.0022 0.0071
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0055 0.0187 0.194
Echinococcus granulosus dna polymerase kappa 0.0096 0.037 0.1238
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0039 0.0117 0.1215
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0044 0.0135 0.23
Trichomonas vaginalis r2r3-MYB transcription factor, putative 0.0062 0.0216 0.224
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0017 0.0018 0.0058
Trichomonas vaginalis MYB, putative 0.0062 0.0217 0.2254
Schistosoma mansoni chromobox protein 0.0148 0.06 0.2009
Echinococcus granulosus mitogen activated protein kinase 3 0.0049 0.0161 0.0538
Leishmania major calcium-translocating P-type ATPase 0.0089 0.0337 0.5696
Brugia malayi hypothetical protein 0.005 0.0165 0.0925
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0018 0.0022 0.0039
Schistosoma mansoni hypothetical protein 0.0686 0.2984 1
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0058 0.0198 0.0711
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0039 0.0117 0.1979
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0055 0.0187 0.194
Echinococcus granulosus Smad4 0.0017 0.0017 0.0056
Echinococcus multilocularis cathepsin L cysteine protease 0.0055 0.0187 0.0624
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0018 0.0022 0.0378
Trypanosoma cruzi cruzipain precursor, putative 0.0146 0.0591 0.105
Leishmania major P-type H -ATPase, putative 0.0042 0.0128 0.2166
Entamoeba histolytica myb-like DNA-binding domain containing protein 0.0062 0.0216 0.3668
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0055 0.0187 0.194
Brugia malayi glutathione reductase 0.0097 0.0372 0.2081
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0034 0.0091 0.1979
Entamoeba histolytica myb-like DNA-binding domain containing protein 0.0062 0.0216 0.3668
Loa Loa (eye worm) RNA binding protein 0.0068 0.0246 0.1204
Brugia malayi Heterochromatin protein 1 0.0148 0.06 0.3353
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0022 0.0227
Toxoplasma gondii calcium-translocating P-type ATPase, PMCA-type protein 0.0076 0.0278 0.1001
Brugia malayi ImpB/MucB/SamB family protein 0.0095 0.0365 0.2041
Schistosoma mansoni transcription factor LCR-F1 0.0146 0.0588 0.1969
Echinococcus multilocularis calcium transporting ATPase type 2C member 0.0089 0.0337 0.1127
Loa Loa (eye worm) intermediate filament protein 0.0026 0.0058 0.0284
Brugia malayi Melibiase family protein 0.0066 0.0236 0.1318
Trichomonas vaginalis chromobox protein, putative 0.0148 0.06 0.623
Echinococcus multilocularis cation transporting ATPase 13A3 0.0021 0.0034 0.0114
Brugia malayi cathepsin F-like cysteine proteinase 0.0018 0.0022 0.0122
Echinococcus multilocularis Niemann Pick C1 protein 0.0095 0.0365 0.1222
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0034 0.0091 0.0049
Trypanosoma cruzi major cysteine proteinase, putative 0.0018 0.0022 0.0039
Schistosoma mansoni hypothetical protein 0.0037 0.0106 0.0352
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0058 0.0198 0.0711
Treponema pallidum 4'-phosphopantetheinyl transferase 0.0023 0.0043 0.0042
Loa Loa (eye worm) hypothetical protein 0.0058 0.0198 0.0969
Loa Loa (eye worm) hypothetical protein 0.0019 0.0027 0.0131
Leishmania major hypothetical protein, conserved 0.0058 0.0198 0.335
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0246 0.1032 0.14
Plasmodium falciparum 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0058 0.0198 0.5029
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0058 0.0198 0.2057
Trichomonas vaginalis cGMP-inhibited 3,5-cyclic phosphodiesterase, putative 0.0058 0.0198 0.2057
Mycobacterium tuberculosis Probable dehydrogenase 0.0221 0.0923 0.1246
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.0058 0.0198 0.0662
Trypanosoma brucei hypothetical protein, conserved 0.0023 0.0043 0.0721
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0058 0.0198 0.0352
Trichomonas vaginalis maltase-glucoamylase, putative 0.0035 0.0097 0.1013
Loa Loa (eye worm) hypothetical protein 0.0026 0.0056 0.0273
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0058 0.0198 0.2057
Loa Loa (eye worm) hypothetical protein 0.0018 0.0022 0.0107
Leishmania major proton motive ATPase, putative 0.0021 0.0034 0.0581
Schistosoma mansoni cation-transporting ATPase 0.0021 0.0034 0.0114
Trypanosoma brucei DNA polymerase kappa, putative 0.0096 0.037 0.6255
Brugia malayi RNA recognition motif domain containing protein 0.0068 0.0246 0.1376
Loa Loa (eye worm) hypothetical protein 0.0081 0.0299 0.1465
Mycobacterium leprae PROBABLE UDP-N-ACETYLGLUCOSAMINE 1-CARBOXYVINYLTRANSFERASE MURA 0.1628 0.7165 1
Loa Loa (eye worm) hypothetical protein 0.0026 0.0056 0.0273
Onchocerca volvulus 0.0121 0.0477 0.4951
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0007 0.0072
Entamoeba histolytica cysteine proteinase, putative 0.0039 0.0117 0.1989
Entamoeba histolytica cysteine protease, putative 0.0039 0.0117 0.1989
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0058 0.0598
Schistosoma mansoni polycystin 1-related 0.0019 0.0027 0.0088
Trichomonas vaginalis CMGC family protein kinase 0.0049 0.0161 0.1673
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.0416 0.1788 0.5992
Echinococcus multilocularis cAMP and cAMP inhibited cGMP 3',5' cyclic 0.0058 0.0198 0.0662
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0034 0.0091 0.1542
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0058 0.0198 0.2057
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0058 0.0198 0.2057
Schistosoma mansoni cation-transporting atpase worm 0.0021 0.0034 0.0114
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0033 0.0091 0.0943
Giardia lamblia CAMP-specific 3,5-cyclic phosphodiesterase 4B 0.0474 0.2044 1
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0058 0.0198 0.0711
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0058 0.0198 0.1107
Trichomonas vaginalis conserved hypothetical protein 0.0054 0.0184 0.1908
Brugia malayi Animal haem peroxidase family protein 0.0026 0.0056 0.0313
Entamoeba histolytica cysteine proteinase, putative 0.0055 0.0187 0.3176
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0034 0.0091 0.0304
Brugia malayi hypothetical protein 0.0118 0.0465 0.2601
Schistosoma mansoni multiple ankyrin repeats single kh domain protein 0.0087 0.0328 0.1099
Entamoeba histolytica cysteine protease, putative 0.0039 0.0117 0.1989
Entamoeba histolytica hypothetical protein 0.0146 0.0588 1
Schistosoma mansoni microtubule-associated protein tau 0.0668 0.2907 0.9743
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0055 0.0187 0.194
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0044 0.0135 0.024
Plasmodium vivax phosphodiesterase gamma, putative 0.0058 0.0198 0.5029
Trypanosoma brucei unspecified product 0.0049 0.0158 0.2677
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0073 0.0243
Mycobacterium ulcerans metal cation transporter ATPase p-type CtpE 0.0021 0.0034 0.0024
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0055 0.0187 0.194
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.0018 0.0022 0.0107
Echinococcus granulosus lipoxygenase domain containing protein 0.0019 0.0027 0.0088
Plasmodium falciparum thioredoxin reductase 0.0034 0.0091 0.1979
Brugia malayi calcium ATPase 0.0034 0.0093 0.0517
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0073 0.0243
Schistosoma mansoni ATPase 0.0089 0.0337 0.1127
Brugia malayi latrophilin 2 splice variant baaae 0.0037 0.0106 0.0591
Trypanosoma brucei P-type H+-ATPase, putative 0.0042 0.0128 0.2166
Leishmania major cysteine peptidase A (CPA) 0.0055 0.0187 0.3159
Trypanosoma cruzi plasma membrane Ca2+ ATPase 0.0076 0.0278 0.0494
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0034 0.0091 0.1542
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0033 0.0091 0.0943
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0146 0.0591 1
Echinococcus multilocularis chromobox protein 2 0.0033 0.0091 0.0303
Loa Loa (eye worm) blistered cuticle protein 3 0.0026 0.0056 0.0273
Loa Loa (eye worm) hypothetical protein 0.0018 0.0024 0.0117
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0023 0.0042 0.014
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.0097 0.1013
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0034 0.0092 0.0951
Trypanosoma brucei DNA polymerase kappa, putative 0.0096 0.037 0.6255
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0474 0.2044 0.685
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0056 0.0586
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0046 0.0482
Schistosoma mansoni cathepsin F (C01 family) 0.0055 0.0187 0.0624
Trichomonas vaginalis cation-transporting ATPase, putative 0.0021 0.0034 0.0357
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0035 0.0097 0.0349
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0034 0.0091 0.0162
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0014 0.0004 0.0019
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0015 0.0007 0.0022
Entamoeba histolytica Plasma membrane calcium-transporting ATPase, putative 0.0076 0.0278 0.4735
Leishmania major DNA polymerase kappa, putative 0.0077 0.0284 0.4802
Echinococcus multilocularis cathepsin b 0.0018 0.0022 0.0071
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0058 0.0198 0.2057
Echinococcus multilocularis peroxidasin 0.0026 0.0056 0.0186
Mycobacterium ulcerans hypothetical protein 0.0022 0.0039 0.0029
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0221 0.0923 0.1246
Entamoeba histolytica Plasma membrane calcium-transporting ATPase, putative 0.0076 0.0278 0.4735
Toxoplasma gondii haloacid dehalogenase family hydrolase domain-containing protein 0.0021 0.0034 0.0122
Trypanosoma brucei DNA polymerase kappa, putative 0.0096 0.037 0.6255
Toxoplasma gondii shikimate dehydrogenase substrate binding domain-containing protein 0.0639 0.2778 1
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0146 0.0588 0.1969
Trichomonas vaginalis glutathione reductase, putative 0.0034 0.0091 0.0947
Echinococcus multilocularis Chromo domain 0.0033 0.0091 0.0303
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0058 0.0198 0.2057
Trypanosoma cruzi hypothetical protein, conserved 0.0058 0.0198 0.0352
Loa Loa (eye worm) CXXC zinc finger family protein 0.0028 0.0066 0.0321
Echinococcus multilocularis protein dispatched 1 0.0047 0.0149 0.0499
Trypanosoma brucei copper-transporting ATPase-like protein, putative 0.0021 0.0034 0.0581
Echinococcus multilocularis chromobox protein 1 0.0148 0.06 0.2009
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0034 0.0091 0.0162
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0024 0.0048 0.0813
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0033 0.0091 0.0303
Brugia malayi hypothetical protein 0.0119 0.0469 0.262
Mycobacterium ulcerans DNA polymerase IV 0.0096 0.037 0.036
Schistosoma mansoni cathepsin B (C01 family) 0.0018 0.0022 0.0071
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0055 0.0187 0.194
Echinococcus multilocularis mitogen activated protein kinase 3 0.0049 0.0161 0.0538
Trichomonas vaginalis phospholipid-transporting ATPase, putative 0.0021 0.0034 0.0357
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0146 0.0591 1
Brugia malayi hypothetical protein 0.0229 0.0958 0.5358
Schistosoma mansoni chromobox protein 0.0033 0.0091 0.0303
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.0063 0.022 0.2286
Brugia malayi hypothetical protein 0.0013 0 0.0003
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0055 0.0187 0.194
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0058 0.0198 0.2057
Echinococcus granulosus netrin receptor unc 5 0.0014 0.0004 0.0012
Toxoplasma gondii Myb family DNA-binding domain-containing protein 0.0062 0.0217 0.0779
Echinococcus multilocularis calcium:calmodulin dependent 3',5' cyclic 0.0058 0.0198 0.0662
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0058 0.0198 0.2057
Entamoeba histolytica cysteine protease, putative 0.0018 0.0022 0.0371
Trichomonas vaginalis r2r3-MYB transcription factor, putative 0.0062 0.0217 0.2254
Echinococcus granulosus L aminoadipate semialdehyde 0.0081 0.0299 0.1002
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0071 0.0255 0.0855
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0086 0.0891
Entamoeba histolytica cysteine protease, putative 0.0039 0.0117 0.1989
Trichomonas vaginalis conserved hypothetical protein 0.0088 0.0332 0.3452
Loa Loa (eye worm) cyclic AMP specific phosphodiesterase PDE4D5A 0.0416 0.1788 0.8748
Onchocerca volvulus 0.0026 0.0058 0.0602
Onchocerca volvulus Peroxidase homolog 0.0026 0.0056 0.058
Onchocerca volvulus 0.0026 0.0056 0.058
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0058 0.0198 0.0711
Brugia malayi M-phase phosphoprotein, mpp8 0.0121 0.0477 0.2667
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0034 0.0091 0.1979
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0021 0.0037 0.0208
Schistosoma mansoni mixed-lineage leukemia protein mll 0.006 0.0209 0.0698
Loa Loa (eye worm) hypothetical protein 0.0058 0.0198 0.0969
Mycobacterium ulcerans cation transporter p-type ATPase D CtpD 0.0021 0.0034 0.0024
Trypanosoma cruzi cAMP phosphodiesterase A, putative 0.0058 0.0198 0.0352
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0035 0.0097 0.1658
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0091 0.0943
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.0018 0.0022 0.0369
Trypanosoma brucei DNA polymerase eta, putative 0.0095 0.0365 0.6174
Schistosoma mansoni hypothetical protein 0.0039 0.0117 0.0391
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0033 0.0091 0.1543
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0058 0.0198 0.2057
Trypanosoma brucei hypothetical protein, conserved 0.0022 0.0039 0.0666
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0018 0.0022 0.0071
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0099 0.0382 0.128
Onchocerca volvulus 0.0048 0.0155 0.1606
Schistosoma mansoni survival motor neuron protein 0.0047 0.0149 0.0499
Mycobacterium ulcerans metal cation transporter p-type ATPase, CtpV 0.0021 0.0034 0.0024
Schistosoma mansoni cpg binding protein 0.0028 0.0066 0.0218
Brugia malayi CHD4 protein 0.0035 0.0098 0.0547
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0081 0.0299 0.1674
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0033 0.0091 0.0943
Onchocerca volvulus 0.023 0.0963 1
Echinococcus granulosus cathepsin L cysteine protease 0.0039 0.0117 0.039
Loa Loa (eye worm) RecQ helicase 0.0045 0.014 0.0687
Trypanosoma cruzi phospholipid-transporting ATPase-like protein, putative 0.0013 0 0.0001
Plasmodium vivax vivapain-2 0.0055 0.0187 0.4707
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0034 0.0091 0.1542
Leishmania major hypothetical protein, conserved 0.0058 0.0198 0.335
Echinococcus multilocularis cysteine protease 0.0055 0.0187 0.0624
Schistosoma mansoni plasma membrane calcium-transporting atpase 0.0063 0.022 0.0736
Loa Loa (eye worm) hypothetical protein 0.0033 0.0091 0.0444
Entamoeba histolytica myb-like DNA-binding domain containing protein 0.0062 0.0216 0.3668
Echinococcus granulosus mitogen activated protein kinase 0.0049 0.0161 0.0538
Entamoeba histolytica cysteine proteinase 2 0.0039 0.0117 0.1989
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0146 0.0591 1
Chlamydia trachomatis phosphoshikimate 1-carboxyl vinyltransferase 0.0639 0.2778 0.2753
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.0474 0.2044 0.685
Trypanosoma brucei DNA polymerase kappa, putative 0.0096 0.037 0.6255
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0067 0.0701
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0034 0.0091 0.0081
Schistosoma mansoni camp/cgmp cyclic nucleotide phosphodiesterase 0.0058 0.0198 0.0662
Schistosoma mansoni camp-specific cyclic nucleotide phosphodiesterase 0.0058 0.0198 0.0662
Loa Loa (eye worm) hypothetical protein 0.0119 0.0469 0.2292
Trypanosoma cruzi trypanothione reductase, putative 0.0034 0.0091 0.0162
Schistosoma mansoni hypothetical protein 0.0023 0.0042 0.014
Loa Loa (eye worm) hypothetical protein 0.0121 0.0477 0.2336
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0071 0.0259 0.0865
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0058 0.0198 0.2057
Loa Loa (eye worm) hypothetical protein 0.0121 0.0477 0.2333
Loa Loa (eye worm) doublecortin family protein 0.0019 0.0027 0.0131
Echinococcus granulosus dna polymerase eta 0.0095 0.0365 0.1222
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0022 0.0227
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0034 0.0091 0.1542
Giardia lamblia DNA damage repair protein 0.0022 0.0039 0.0087
Leishmania major DNA polymerase kappa, putative 0.0022 0.0039 0.0666
Loa Loa (eye worm) Smad1 0.0017 0.0017 0.0084
Echinococcus multilocularis phospholipid transporting ATPase IIB 0.0021 0.0034 0.0114
Onchocerca volvulus Huntingtin homolog 0.0119 0.0469 0.4865
Schistosoma mansoni ankyrin 23/unc44 0.0014 0.0004 0.0012
Brugia malayi hypothetical protein 0.0019 0.0027 0.015
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0058 0.0198 0.1107
Mycobacterium ulcerans metal cation-transporting p-type ATPase CtpC 0.0021 0.0034 0.0024
Brugia malayi hypothetical protein 0.0019 0.0027 0.015
Echinococcus multilocularis mothers against decapentaplegic 5 0.0017 0.0017 0.0056
Loa Loa (eye worm) hypothetical protein 0.0026 0.0056 0.0273
Loa Loa (eye worm) hypothetical protein 0.0474 0.2044 1
Onchocerca volvulus 0.0055 0.0187 0.1938
Mycobacterium ulcerans cation-transporter p-type ATPase B CtpB 0.0021 0.0034 0.0024
Loa Loa (eye worm) hypothetical protein 0.0026 0.0056 0.0273
Entamoeba histolytica myb-like DNA-binding domain containing protein 0.0062 0.0216 0.3668
Schistosoma mansoni smad1 5 8 and 0.0017 0.0017 0.0056
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.0018 0.0024 0.0062
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0033 0.0091 0.0303
Trichomonas vaginalis C-MYB, putative 0.0062 0.0216 0.224
Plasmodium falciparum phosphodiesterase gamma, putative 0.0058 0.0198 0.5029
Echinococcus multilocularis dual 3',5' cyclic AMP and GMP phosphodiesterase 0.0058 0.0198 0.0662
Onchocerca volvulus Cathepsin L homolog 0.0018 0.0022 0.0226
Loa Loa (eye worm) ctsf protein 0.0055 0.0187 0.0913
Echinococcus multilocularis cysteine protease 0.0055 0.0187 0.0624
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0034 0.0091 0.0162
Entamoeba histolytica plasma membrane calcium ion-transporting ATPase, putative 0.0039 0.0114 0.1936
Trypanosoma cruzi calcium motive p-type ATPase, putative 0.0053 0.0176 0.0312
Entamoeba histolytica cysteine proteinase, putative 0.0034 0.0092 0.1557
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.0028 0.0068 0.0242
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0018 0.0022 0.0071
Echinococcus granulosus bloom syndrome protein 0.0045 0.014 0.0469
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0086 0.0891
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0097 0.0173
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0091 0.0943
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0055 0.0187 0.194
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.0097 0.1013
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0022 0.0227
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0044 0.0135 0.0452
Entamoeba histolytica cysteine proteinase 1, putative 0.0039 0.0117 0.1989
Echinococcus multilocularis Alpha N acetylgalactosaminidase 0.0099 0.0382 0.128
Schistosoma mansoni hypothetical protein 0.0039 0.0117 0.0391
Trichomonas vaginalis r2r3-MYB transcription factor, putative 0.0062 0.0216 0.224
Giardia lamblia GTOR 0.0044 0.0135 0.0561
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.0416 0.1788 0.5992
Entamoeba histolytica plasma membrane calcium-transporting ATPase 1, putative 0.0047 0.0151 0.2565
Toxoplasma gondii P-type ATPase PMA1 0.0042 0.0128 0.0459
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0097 0.0372 0.1244
Giardia lamblia Myb 1-like protein 0.0062 0.0217 0.0965
Brugia malayi Latrophilin receptor protein 2 0.0017 0.0018 0.01
Plasmodium vivax cation transporting ATPase, putative 0.0021 0.0034 0.0358
Brugia malayi Cathepsin L-like precursor 0.0055 0.0187 0.1044
Echinococcus granulosus GPCR family 2 0.0017 0.0018 0.0058
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0033 0.0091 0.0325
Brugia malayi Probable 3',5'-cyclic phosphodiesterase T04D3.3, putative 0.0058 0.0198 0.1107
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.0014 0.0004 0.0012
Trypanosoma brucei DNA polymerase kappa, putative 0.0048 0.0154 0.2599
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0058 0.0198 0.0711
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.0058 0.0198 0.0662
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0018 0.0022 0.0071
Toxoplasma gondii P-type ATPase4, putative 0.0066 0.0234 0.0842
Onchocerca volvulus Peroxidasin homolog 0.0026 0.0056 0.058
Entamoeba histolytica phospholipid-transporting P-type ATPase, putative 0.0021 0.0034 0.0584
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0034 0.0091 0.008
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0055 0.0187 0.194
Entamoeba histolytica hypothetical protein 0.0033 0.0091 0.1543
Onchocerca volvulus 0.0121 0.0477 0.4951
Echinococcus multilocularis dna polymerase kappa 0.0096 0.037 0.1238
Loa Loa (eye worm) hypothetical protein 0.0021 0.0036 0.0175
Brugia malayi cathepsin Z-like cysteine proteinase 0.0018 0.0022 0.0122
Echinococcus granulosus chromobox protein 2 0.0033 0.0091 0.0303
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0055 0.0187 0.4707
Trypanosoma cruzi calcium motive p-type ATPase, putative 0.0053 0.0176 0.0312
Brugia malayi MH2 domain containing protein 0.0248 0.1042 0.5829
Brugia malayi E1-E2 ATPase family protein 0.0042 0.0128 0.0716
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0018 0.0022 0.0371
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0014 0.0004 0.0021
Schistosoma mansoni hypothetical protein 0.0017 0.0018 0.0058
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0058 0.0198 0.0711
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0039 0.0117 0.1979
Echinococcus granulosus cation transporting atpase worm 0.0021 0.0034 0.0114
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0058 0.0198 0.2057
Schistosoma mansoni smad1 5 8 and 0.0017 0.0017 0.0056
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0022 0.0039 0.014
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0086 0.0891
Onchocerca volvulus 0.0055 0.0187 0.1938
Echinococcus granulosus nuclear factor of activated T cells 5 0.0071 0.0259 0.0865
Brugia malayi Bloom's syndrome protein homolog 0.0045 0.014 0.0785
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0055 0.0187 0.194
Mycobacterium tuberculosis Possible metal cation transporting P-type ATPase CtpH 0.0045 0.0141 0.0149
Loa Loa (eye worm) hypothetical protein 0.0014 0.0004 0.0019
Toxoplasma gondii E1-E2 ATPase subfamily protein 0.0029 0.007 0.0249
Echinococcus granulosus cpg binding protein 0.0029 0.0073 0.0242
Echinococcus multilocularis high affinity cAMP specific 3',5' cyclic 0.0058 0.0198 0.0662
Onchocerca volvulus 0.0055 0.0187 0.1938
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0018 0.0022 0.0227
Brugia malayi fibroinase precursor 0.0018 0.0022 0.0122
Trypanosoma brucei DNA polymerase kappa, putative 0.0055 0.0187 0.3156
Trypanosoma cruzi P-type H+-ATPase, putative 0.0042 0.0128 0.0227
Loa Loa (eye worm) hypothetical protein 0.0307 0.1305 0.6386
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.004 0.0119 0.1233
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0018 0.0024 0.0085
Echinococcus granulosus expressed conserved protein 0.009 0.034 0.1136
Trypanosoma brucei trypanothione reductase 0.0097 0.0372 0.6296
Echinococcus multilocularis Glycoside hydrolase, family 27 0.0099 0.0382 0.128
Onchocerca volvulus Netrin receptor homolog 0.0014 0.0004 0.0041
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.0014 0.0004 0.0012
Plasmodium falciparum non-SERCA-type Ca2+ -transporting P-ATPase 0.0089 0.0337 0.8987
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0091 0.0943
Schistosoma mansoni hypothetical protein 0.0047 0.0149 0.0499
Echinococcus granulosus neuropeptide receptor A26 0.0457 0.1969 0.6599
Trypanosoma cruzi hypothetical protein, conserved 0.0058 0.0198 0.0352
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0007 0.0072
Plasmodium vivax copper-transporting ATPase, putative 0.0021 0.0034 0.0358
Schistosoma mansoni hypothetical protein 0.0014 0.0004 0.0012
Entamoeba histolytica cysteine protease, putative 0.0039 0.0117 0.1989
Toxoplasma gondii cathepsin CPC2 0.0018 0.0022 0.0077
Echinococcus granulosus Ankyrin 0.0014 0.0004 0.0013
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0058 0.0198 0.2057
Schistosoma mansoni patched 1 0.0041 0.0124 0.0413
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0096 0.0994
Loa Loa (eye worm) hypothetical protein 0.0019 0.0027 0.0131
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0081 0.0299 0.1002
Echinococcus granulosus Na:K ATPase alpha subunit 0.0053 0.0176 0.0588
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0034 0.0091 0.1979
Trypanosoma cruzi hypothetical protein, conserved 0.0022 0.0039 0.007
Toxoplasma gondii Alpha-galactosidase 0.0014 0.0004 0.0014
Plasmodium falciparum glutathione reductase 0.0034 0.0091 0.1979
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0015 0.0007 0.0117
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0246 0.1032 0.14
Onchocerca volvulus 0.0028 0.0066 0.068
Echinococcus granulosus X box binding protein 1 0.0279 0.118 0.3954
Trypanosoma brucei 3', 5'-cyclic nucleotide phosphodiesterase, putative 0.0058 0.0198 0.335
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0058 0.0198 0.0662
Echinococcus granulosus thioredoxin glutathione reductase 0.0097 0.0372 0.1246
Plasmodium falciparum DNA repair protein REV1, putative 0.0022 0.0039 0.0502
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0096 0.0994
Schistosoma mansoni cgmp-dependent 35-cyclic phosphodiesterase 0.0058 0.0198 0.0662
Brugia malayi Valyl-tRNA synthetase 0.0033 0.0091 0.0507
Brugia malayi Sodium/potassium-transporting ATPase alpha chain, putative 0.0045 0.0141 0.0786
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0058 0.0198 0.0711
Echinococcus multilocularis netrin receptor unc 5 0.0014 0.0004 0.0012
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0058 0.0198 0.0711
Trypanosoma brucei DNA polymerase kappa, putative 0.0048 0.0154 0.2599
Trichomonas vaginalis PIKK family atypical protein kinase 0.0044 0.0135 0.1405
Echinococcus multilocularis lysosomal alpha glucosidase 0.0158 0.0642 0.2151
Trichomonas vaginalis Clan CA, family C1, cathepsin L or H-like cysteine peptidase 0.0018 0.0022 0.0227
Loa Loa (eye worm) hypothetical protein 0.0026 0.0056 0.0273
Echinococcus granulosus cathepsin L 0.0018 0.0022 0.0071
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0018 0.0022 0.0107
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0035 0.0097 0.1013
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0049 0.0161 0.0286
Schistosoma mansoni alpha glucosidase 0.0035 0.0097 0.0325
Entamoeba histolytica phospholipid-transporting P-type ATPase, putative 0.0021 0.0034 0.0584
Brugia malayi Cathepsin L-like precursor 0.0034 0.0092 0.0512
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0063 0.0222 0.0742
Schistosoma mansoni calcium-transporting atpase sarcoplasmic/endoplasmic reticulum type (calcium pump) 0.0076 0.0278 0.0931
Loa Loa (eye worm) E1-E2 ATPase 0.0042 0.0128 0.0626
Loa Loa (eye worm) hypothetical protein 0.0034 0.0092 0.0448
Brugia malayi Papain family cysteine protease containing protein 0.0055 0.0187 0.1044
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0015 0.0007 0.0039
Giardia lamblia Copper-transporting P-type ATPase 0.0021 0.0034 0.0062
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.0076 0.0278 0.2892
Trypanosoma cruzi proton motive ATPase 1, putative 0.0013 0 0.0001
Echinococcus granulosus phospholipid transporting ATPase IIB 0.0021 0.0034 0.0114
Echinococcus granulosus lipoxygenase domain containing protein 0.0019 0.0027 0.0088
Echinococcus multilocularis neutral alpha glucosidase AB 0.0035 0.0097 0.0325
Brugia malayi Sodium/potassium-transporting ATPase alpha-3 chain, putative 0.0029 0.007 0.039
Echinococcus multilocularis GPCR, family 2 0.0017 0.0018 0.0058
Echinococcus granulosus mothers against decapentaplegic 5 0.0017 0.0017 0.0056
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0049 0.0161 0.2725
Loa Loa (eye worm) hypothetical protein 0.0048 0.0154 0.0752
Loa Loa (eye worm) hypothetical protein 0.0088 0.0332 0.1625
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0055 0.0187 0.4707
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.003 0.0075 0.0267
Schistosoma mansoni hypothetical protein 0.0033 0.0091 0.0303
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0146 0.0591 1
Schistosoma mansoni cation-transporting atpase 13a1 (G-box binding protein) 0.0021 0.0034 0.0114
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0055 0.0187 0.194
Trypanosoma brucei DNA damage repair protein, putative 0.0022 0.0039 0.0666
Brugia malayi MH2 domain containing protein 0.0017 0.0017 0.0096
Plasmodium vivax vivapain-1 0.0039 0.0117 0.2716
Loa Loa (eye worm) hypothetical protein 0.0018 0.0022 0.0107
Brugia malayi cathepsin L-like cysteine proteinase 0.0018 0.0022 0.0122
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0035 0.0098 0.0326
Schistosoma mansoni calcium-transporting atpase 2 (atpase 2) 0.0076 0.0278 0.0931
Trypanosoma cruzi cation-transporting ATPase, putative 0.0021 0.0034 0.0061
Trypanosoma brucei hypothetical protein, conserved 0.0022 0.0039 0.0666
Schistosoma mansoni peroxidasin 0.0026 0.0056 0.0186
Onchocerca volvulus Peroxidasin homolog 0.0026 0.0056 0.058
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0058 0.0198 0.0352
Brugia malayi TAR-binding protein 0.0068 0.0246 0.1376
Treponema pallidum UDP-N-acetylglucosamine 1-carboxyvinyltransferase 0.2267 1 1
Loa Loa (eye worm) hypothetical protein 0.0018 0.0022 0.0107
Loa Loa (eye worm) hypothetical protein 0.0026 0.0056 0.0273
Trypanosoma brucei calcium-transporting ATPase, putative 0.0032 0.0082 0.1391
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0034 0.0091 0.0057
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0086 0.0891
Echinococcus granulosus cathepsin L cysteine proteinase 0.0055 0.0187 0.0624
Brugia malayi Thioredoxin reductase 0.0097 0.0372 0.2081
Trypanosoma cruzi hypothetical protein, conserved 0.0058 0.0198 0.0352
Entamoeba histolytica cysteine proteinase, putative 0.0039 0.0117 0.1989
Brugia malayi Na,K-ATPase alpha subunit 0.0066 0.0234 0.131
Trypanosoma brucei cAMP-specific phosphodiesterase 0.0058 0.0198 0.335
Loa Loa (eye worm) heterochromatin protein 1 0.0148 0.06 0.2934
Echinococcus multilocularis protein patched 0.0041 0.0124 0.0413
Brugia malayi Cathepsin L-like precursor 0.0055 0.0187 0.1044
Trypanosoma cruzi calcium-transporting ATPase, putative 0.0032 0.0082 0.0146
Trypanosoma cruzi trypanothione reductase, putative 0.0097 0.0372 0.0661
Brugia malayi potential phospholipid-transporting ATPase IIB, putative 0.0021 0.0034 0.0192
Schistosoma mansoni intermediate filament proteins 0.0026 0.0058 0.0193
Echinococcus granulosus cathepsin l1 0.0055 0.0187 0.0624
Trypanosoma cruzi DNA polymerase kappa, putative 0.0096 0.037 0.0657
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0094 0.0358 0.3719
Trypanosoma brucei cAMP-specific phosphodiesterase 0.0058 0.0198 0.335
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0021 0.0033 0.0566
Loa Loa (eye worm) hypothetical protein 0.0044 0.0138 0.0676
Loa Loa (eye worm) hypothetical protein 0.0026 0.0056 0.0273
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0058 0.0198 0.0711
Trypanosoma cruzi cruzipain precursor, putative 0.1282 0.563 1
Trichomonas vaginalis conserved hypothetical protein 0.0058 0.0198 0.2057
Brugia malayi hypothetical protein 0.0121 0.0477 0.267
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0146 0.0591 1
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0058 0.0198 0.0352
Plasmodium falciparum calcium-transporting ATPase 0.0076 0.0278 0.7322
Trichomonas vaginalis set domain proteins, putative 0.023 0.0963 1
Trypanosoma brucei protein kinase, putative 0.0049 0.0161 0.2725
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0033 0.0091 0.1968
Leishmania major cytochrome p450-like protein 0.0015 0.001 0.0173
Leishmania major cathepsin L-like protease 0.0055 0.0187 0.3159
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.0474 0.2044 0.685
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0018 0.0022 0.0371
Trypanosoma brucei DNA polymerase kappa, putative 0.0096 0.037 0.6255
Echinococcus multilocularis L aminoadipate semialdehyde 0.0081 0.0299 0.1002
Loa Loa (eye worm) hypothetical protein 0.0033 0.0091 0.0444
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0086 0.0891
Echinococcus granulosus survival motor neuron protein 1 0.0229 0.0958 0.321
Loa Loa (eye worm) hypothetical protein 0.0026 0.0058 0.0284
Trichomonas vaginalis chromobox protein, putative 0.0094 0.0358 0.3721
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0058 0.0198 0.2057
Loa Loa (eye worm) hypothetical protein 0.0119 0.0469 0.2292
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0024 0.0048 0.0813
Trichomonas vaginalis r2r3-MYB transcription factor, putative 0.0062 0.0216 0.224
Schistosoma mansoni hypothetical protein 0.0039 0.0117 0.0391
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.0076 0.0278 0.2892
Schistosoma mansoni hypothetical protein 0.0017 0.0018 0.0058
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0146 0.0591 1
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0037 0.0106 0.1098
Mycobacterium leprae PROBABLE CATION-TRANSPORTER ATPASE I CTPI 0.0045 0.0141 0.0149
Schistosoma mansoni DNA polymerase IV / kappa 0.0022 0.0039 0.013
Echinococcus granulosus Alpha N acetylgalactosaminidase 0.0099 0.0382 0.128
Onchocerca volvulus Cathepsin F homolog 0.0055 0.0187 0.1938
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0034 0.0091 0.1542
Trichomonas vaginalis PIKK family atypical protein kinase 0.0044 0.0135 0.1405
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0221 0.0923 0.1246
Echinococcus multilocularis calcium transporting atpase 0.0076 0.0278 0.0931
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0044 0.0135 0.23
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0023 0.0042 0.014
Entamoeba histolytica plasma membrane calcium-transporting ATPase, putative 0.0018 0.002 0.0343
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0046 0.0482
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0007 0.0072
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0099 0.0382 0.128
Entamoeba histolytica cysteine protease, putative 0.0018 0.0022 0.0371
Trichomonas vaginalis CMGC family protein kinase 0.0049 0.0161 0.1673
Brugia malayi cytoplasmic intermediate filament protein 0.0014 0.0004 0.0024
Echinococcus multilocularis tumor protein p63 0.0327 0.1394 0.4671
Brugia malayi Pre-SET motif family protein 0.003 0.0073 0.0409
Echinococcus multilocularis expressed conserved protein 0.009 0.034 0.1136
Echinococcus multilocularis survival motor neuron protein 1 0.0229 0.0958 0.321
Entamoeba histolytica cysteine protease, putative 0.0039 0.0117 0.1989
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0058 0.0198 0.2057
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0034 0.0092 0.0951
Brugia malayi Cathepsin L-like precursor 0.0055 0.0187 0.1044
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0058 0.0198 0.2057
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.0058 0.0198 0.2057
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0033 0.0091 0.0303
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0058 0.0198 0.2057
Entamoeba histolytica cysteine protease, putative 0.0018 0.0022 0.0371
Trichomonas vaginalis conserved hypothetical protein 0.0054 0.0184 0.1908
Toxoplasma gondii heavy metal translocating P-type ATPase subfamily protein 0.0021 0.0034 0.0122
Loa Loa (eye worm) hypothetical protein 0.0018 0.0022 0.0107
Giardia lamblia hypothetical protein 0.0058 0.0198 0.0871
Trichomonas vaginalis hypothetical protein 0.0033 0.0091 0.0943
Mycobacterium leprae probable 3-phosphoshikimate 1-carboxyvinyl transferase AroA (5-ENOLPYRUVYLSHIKIMATE-3-PHOSPHATE SYNTHASE) (EPSP SYNTHASE) (EPSPS 0.0639 0.2778 0.3847
Giardia lamblia Sgs1 DNA helicase, putative 0.0018 0.0024 0.0011
Wolbachia endosymbiont of Brugia malayi UDP-N-acetylglucosamine 1-carboxyvinyltransferase 0.2267 1 1
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0015 0.0007 0.0012
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0055 0.0187 0.194
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0018 0.0022 0.0071
Trypanosoma brucei DNA polymerase IV, putative 0.009 0.0341 0.5776
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0018 0.0022 0.0071
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0077 0.0284 0.035
Echinococcus granulosus cAMP and cAMP inhibited cGMP 3'5' cyclic 0.0058 0.0198 0.0662
Echinococcus multilocularis Polycystic kidney disease protein 0.0019 0.0027 0.0088
Trichomonas vaginalis pc-MYB2, putative 0.0062 0.0216 0.224
Brugia malayi cathepsin B-like cysteine proteinase 0.0018 0.0022 0.0122
Trypanosoma cruzi hypothetical protein, conserved 0.0058 0.0198 0.0352
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.004 0.0119 0.1233
Brugia malayi MH1 domain containing protein 0.0017 0.0017 0.0096
Trichomonas vaginalis cation-transporting ATPase, putative 0.0089 0.0337 0.3497
Echinococcus granulosus lamin 0.0026 0.0058 0.0193
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0221 0.0923 0.1246
Trypanosoma brucei cytochrome P450, putative 0.0015 0.001 0.0173
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0028 0.0066 0.0219
Onchocerca volvulus Huntingtin homolog 0.0119 0.0469 0.4865
Loa Loa (eye worm) hypothetical protein 0.0021 0.0034 0.0168
Schistosoma mansoni calcium-transporting atpase sarcoplasmic/endoplasmic reticulum type (calcium pump) 0.0076 0.0278 0.0931
Schistosoma mansoni cathepsin F (C01 family) 0.0034 0.0092 0.0305
Schistosoma mansoni tar DNA-binding protein 0.0068 0.0246 0.0823
Loa Loa (eye worm) calcium ATPase 0.0047 0.0151 0.0738
Schistosoma mansoni multiple ankyrin repeats single kh domain protein 0.0087 0.0328 0.1099
Echinococcus multilocularis lipoxygenase domain containing protein 0.0019 0.0027 0.0088
Schistosoma mansoni plasma membrane calcium-transporting atpase 0.0063 0.022 0.0736
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.004 0.0119 0.1233
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0055 0.0187 0.194
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0158 0.0642 0.3142
Entamoeba histolytica cysteine proteinase, putative 0.0039 0.0117 0.1989
Echinococcus multilocularis cathepsin L 0.0039 0.0117 0.039
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0035 0.0097 0.1013
Plasmodium vivax unspecified product 0.0021 0.0037 0.0442
Brugia malayi Calcitonin receptor-like protein seb-1 0.0054 0.0181 0.1014
Trichomonas vaginalis cation-transporting ATPase, putative 0.0076 0.0278 0.2892
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0017 0.0018 0.01
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0055 0.0187 0.0624
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0025 0.0052 0.0289
Echinococcus granulosus lamin dm0 0.0026 0.0058 0.0193
Loa Loa (eye worm) cytochrome P450 family protein 0.0015 0.001 0.005
Trichomonas vaginalis r2r3-MYB transcription factor, putative 0.0062 0.0216 0.224
Echinococcus granulosus cation transporting ATPase 13A1 0.0021 0.0034 0.0114
Trichomonas vaginalis cation-transporting ATPase fungi, putative 0.0076 0.0278 0.2892
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0034 0.0091 0.051
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0018 0.0024 0.0134
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0091 0.0943
Trichomonas vaginalis pc-MYB2, putative 0.0062 0.0216 0.224
Mycobacterium ulcerans 3-phosphoshikimate 1-carboxyvinyltransferase 0.0639 0.2778 0.277
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.004 0.0119 0.1233
Loa Loa (eye worm) cytochrome P450 family protein 0.0015 0.001 0.005
Loa Loa (eye worm) hypothetical protein 0.0095 0.0365 0.1785
Entamoeba histolytica phospholipid-transporting P-type ATPase, putative 0.0021 0.0034 0.0584
Plasmodium vivax SET domain protein, putative 0.003 0.0073 0.1464
Echinococcus multilocularis dna polymerase eta 0.0095 0.0365 0.1222
Trichomonas vaginalis r2r3-MYB transcription factor, putative 0.0062 0.0216 0.224
Echinococcus multilocularis copper transporting ATPase 1 0.0021 0.0034 0.0114
Loa Loa (eye worm) hypothetical protein 0.005 0.0165 0.0809
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0017 0.0018 0.0058
Echinococcus multilocularis smad 0.0017 0.0017 0.0056
Echinococcus multilocularis Na+:K+ ATPase alpha subunit 0.0053 0.0176 0.0588
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.003 0.0073 0.0243
Trichomonas vaginalis Clan CA, family C1, cathepsin H-like cysteine peptidase 0.0018 0.0022 0.0227
Brugia malayi Cytochrome P450 family protein 0.0025 0.0055 0.0305
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0034 0.0091 0.0049
Loa Loa (eye worm) animal heme peroxidase 0.0026 0.0056 0.0273
Brugia malayi Protein cec-1. 0.0033 0.0091 0.0507
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0015 0.0007 0.0117
Brugia malayi MH2 domain containing protein 0.0017 0.0017 0.0096
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0041 0.0124 0.0605
Schistosoma mansoni tar DNA-binding protein 0.0068 0.0246 0.0823
Trypanosoma cruzi hypothetical protein, conserved 0.0058 0.0198 0.0352
Brugia malayi Cytochrome P450 family protein 0.0015 0.001 0.0057
Brugia malayi Papain family cysteine protease containing protein 0.0039 0.0117 0.0654
Brugia malayi MAP kinase sur-1 0.0049 0.0161 0.0901
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.0018 0.0022 0.0071
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0058 0.0198 0.0711
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0034 0.0091 0.0304
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0018 0.0024 0.0079
Trichomonas vaginalis chromobox protein, putative 0.0033 0.0091 0.0943
Loa Loa (eye worm) hypothetical protein 0.005 0.0165 0.0805
Loa Loa (eye worm) hypothetical protein 0.0026 0.0056 0.0273
Trichomonas vaginalis PIKK family atypical protein kinase 0.0044 0.0135 0.1405
Brugia malayi hypothetical protein 0.0026 0.0056 0.0313
Leishmania major trypanothione reductase 0.0097 0.0372 0.6296
Echinococcus granulosus cathepsin l cysteine peptidase 0.0055 0.0187 0.0624
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0091 0.0943
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0023 0.0043 0.0032
Giardia lamblia Kinase, CMGC MAPK 0.0049 0.0161 0.0689
Echinococcus multilocularis lysosomal alpha glucosidase 0.0158 0.0642 0.2151
Plasmodium vivax DNA repair protein REV1, putative 0.0022 0.0039 0.0502
Echinococcus granulosus smad 0.0017 0.0017 0.0056
Brugia malayi Niemann-Pick C1 protein precursor 0.0095 0.0365 0.2042
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0146 0.0591 1
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0071 0.0255 0.125
Brugia malayi follicle stimulating hormone receptor 0.0234 0.0981 0.5484
Schistosoma mansoni lipoxygenase 0.0019 0.0027 0.0088
Echinococcus granulosus dnaJ subfamily B 0.0396 0.17 0.5696
Onchocerca volvulus 0.0081 0.0299 0.3108
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0146 0.0591 1
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0055 0.0187 0.0913
Entamoeba histolytica hypothetical protein 0.0033 0.0091 0.1543
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0047 0.0149 0.0534
Loa Loa (eye worm) animal heme peroxidase 0.0026 0.0056 0.0273
Brugia malayi cathepsin Z-like cysteine proteinase 0.0018 0.0022 0.0122
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0018 0.0024 0.0117
Loa Loa (eye worm) MH1 domain-containing protein 0.0017 0.0017 0.0084
Entamoeba histolytica recQ family helicase, putative 0.0024 0.0048 0.0817
Trichomonas vaginalis PIKK family atypical protein kinase 0.0023 0.0046 0.048
Mycobacterium ulcerans cation-transporter ATPase I CtpI 0.0045 0.0141 0.013
Trichomonas vaginalis Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase 0.0018 0.0022 0.0227
Loa Loa (eye worm) hypothetical protein 0.0014 0.0004 0.0022
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0018 0.0022 0.0071
Trypanosoma cruzi DNA polymerase kappa, putative 0.0096 0.037 0.0657
Trichomonas vaginalis cation-transporting ATPase, putative 0.0042 0.0128 0.133
Echinococcus multilocularis Tetracycline resistance leader peptide, TetL 0.0076 0.0278 0.0932
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0097 0.0173
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0099 0.0382 0.128
Onchocerca volvulus Dual oxidase homolog 0.0026 0.0056 0.058
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0017 0.0017 0.0056
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0058 0.0198 0.0711
Leishmania major P-type H -ATPase, putative 0.0042 0.0128 0.2166
Entamoeba histolytica cysteine protease, putative 0.0018 0.0022 0.0371
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0055 0.0187 0.194
Onchocerca volvulus 0.0026 0.0056 0.058
Leishmania major cathepsin L-like protease 0.0146 0.0591 1
Trypanosoma cruzi cAMP-specific phosphodiesterase, putative 0.0058 0.0198 0.0352
Entamoeba histolytica calcium-transporting P-type ATPase, putative 0.0066 0.0234 0.3984
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.004 0.0119 0.1233
Mycobacterium tuberculosis Conserved hypothetical protein 0.0071 0.0255 0.031
Onchocerca volvulus 0.006 0.021 0.2176
Trypanosoma cruzi DNA damage repair protein, putative 0.0022 0.0039 0.007
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0099 0.0382 0.128
Loa Loa (eye worm) hypothetical protein 0.0021 0.0034 0.0168
Loa Loa (eye worm) fibroinase 0.0055 0.0187 0.0913
Brugia malayi Cathepsin L-like precursor 0.0055 0.0187 0.1044
Echinococcus multilocularis cation transporting atpase worm 0.0021 0.0034 0.0114
Schistosoma mansoni hypothetical protein 0.0146 0.0588 0.1969
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0058 0.0198 0.1107
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0018 0.0022 0.0107
Trypanosoma brucei vacuolar-type Ca2+-ATPase 2 0.0076 0.0278 0.471
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0034 0.0091 0.0162
Plasmodium vivax thioredoxin reductase, putative 0.0097 0.0372 1
Toxoplasma gondii plasma membrane-type Ca(2+)-ATPase A1 PMCAA1 0.0063 0.022 0.0791
Plasmodium vivax glutathione reductase, putative 0.0097 0.0372 1
Echinococcus granulosus cathepsin L 0.0039 0.0117 0.039
Loa Loa (eye worm) phosphatidylinositol 3 0.0015 0.0007 0.0034
Trypanosoma brucei calcium motive p-type ATPase, putative 0.0053 0.0176 0.2977
Brugia malayi Papain family cysteine protease containing protein 0.0018 0.0022 0.0122
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0091 0.0943
Schistosoma mansoni hypothetical protein 0.0396 0.17 0.5696
Plasmodium vivax calcium-transporting ATPase, putative 0.0089 0.0337 0.8987
Loa Loa (eye worm) glutathione reductase 0.0097 0.0372 0.1821
Entamoeba histolytica hypothetical protein 0.0146 0.0588 1
Schistosoma mansoni rab6-interacting 0.0019 0.0027 0.0088
Toxoplasma gondii target of rapamycin (TOR), putative 0.0032 0.0086 0.0307
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0035 0.0098 0.0326
Loa Loa (eye worm) hypothetical protein 0.0066 0.0234 0.1146
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0055 0.0187 0.194
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0097 0.0372 0.0474
Echinococcus multilocularis Ankyrin 0.0014 0.0004 0.0013
Brugia malayi Animal haem peroxidase family protein 0.0026 0.0056 0.0313
Onchocerca volvulus 0.0018 0.0022 0.0226
Trypanosoma brucei vacuolar-type Ca2+-ATPase 1 0.0076 0.0278 0.471
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0018 0.0022 0.0227
Echinococcus granulosus calcium transporting atpase 0.0076 0.0278 0.0931
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0023 0.0043 0.0594
Echinococcus granulosus Ankyrin repeat domain containing protein 0.0087 0.0328 0.1099
Brugia malayi cathepsin L-like precursor 0.0034 0.0092 0.0512
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0046 0.0482
Brugia malayi Papain family cysteine protease containing protein 0.0018 0.0022 0.0122
Loa Loa (eye worm) hypothetical protein 0.0033 0.0091 0.0444
Onchocerca volvulus 0.0055 0.0187 0.1938
Brugia malayi Animal haem peroxidase family protein 0.0026 0.0056 0.0313
Leishmania major hypothetical protein, conserved 0.005 0.0165 0.2798
Loa Loa (eye worm) latrophilin receptor protein 2 0.0017 0.0018 0.0087
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0034 0.0091 0.1542
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0055 0.0187 0.0624
Echinococcus granulosus high affinity cgmp specific 3' 5' cyclic 0.0058 0.0198 0.0662
Trypanosoma brucei DNA polymerase kappa, putative 0.0096 0.037 0.6255
Brugia malayi Probable 3',5'-cyclic phosphodiesterase C32E12.2, putative 0.0058 0.0198 0.1107
Trypanosoma brucei DNA polymerase kappa, putative 0.0096 0.037 0.6255
Echinococcus granulosus microtubule associated protein 2 0.0668 0.2907 0.9743
Loa Loa (eye worm) helicase 0.0033 0.0091 0.0444
Echinococcus multilocularis cpg binding protein 0.0029 0.0073 0.0242
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.003 0.0073 0.0243
Echinococcus multilocularis thioredoxin glutathione reductase 0.0097 0.0372 0.1246
Echinococcus multilocularis cathepsin L cysteine protease 0.0055 0.0187 0.0624
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0221 0.0923 0.1246
Toxoplasma gondii preprocathepsin c precursor, putative 0.0018 0.0022 0.0077
Trichomonas vaginalis cAMP and cAMP-inhibited cGMP 3,5-cyclic phosphodiesterase, putative 0.0058 0.0198 0.2057
Echinococcus multilocularis neuropeptide receptor A26 0.0457 0.1969 0.6599
Trypanosoma brucei cAMP-specific phosphodiesterase, putative 0.0058 0.0198 0.335
Plasmodium falciparum cGMP-specific phosphodiesterase 0.0058 0.0198 0.5029
Brugia malayi Pre-SET motif family protein 0.0202 0.0839 0.4692
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0015 0.0007 0.0022
Brugia malayi Peroxidasin 0.0026 0.0056 0.0313
Loa Loa (eye worm) hypothetical protein 0.0137 0.0552 0.2698
Trypanosoma brucei hypothetical protein, conserved 0.0058 0.0198 0.335
Onchocerca volvulus 0.0055 0.0187 0.1938
Loa Loa (eye worm) hypothetical protein 0.006 0.021 0.1025
Echinococcus granulosus sarco:endoplasmic reticulum calcium ATPase 0.0089 0.0337 0.1127
Onchocerca volvulus 0.0091 0.0347 0.3603
Giardia lamblia Phospholipid-transporting ATPase IA, putative 0.0021 0.0034 0.0062
Trypanosoma cruzi calcium-translocating P-type ATPase, putative 0.0029 0.007 0.0124
Trichomonas vaginalis C-MYB, putative 0.0062 0.0216 0.224
Brugia malayi Cytochrome P450 family protein 0.0015 0.001 0.0057
Onchocerca volvulus Cathepsin L homolog 0.0055 0.0187 0.1938
Echinococcus granulosus tumor protein p63 0.0327 0.1394 0.4671
Trichomonas vaginalis chromobox protein, putative 0.0148 0.06 0.623
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0058 0.0198 0.0711
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0234 0.0981 0.4798
Trichomonas vaginalis mercuric reductase, putative 0.0034 0.0091 0.0947
Leishmania major copper-transporting ATPase-like protein, putative 0.0021 0.0034 0.0581
Plasmodium vivax P-type ATPase4, putative 0.0089 0.0337 0.8987
Schistosoma mansoni tar DNA-binding protein 0.0068 0.0246 0.0823
Trichomonas vaginalis alpha-galactosidase/alpha-N-acetylgalactosaminidase, putative 0.0066 0.0236 0.2448
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0039 0.0117 0.1215
Toxoplasma gondii melibiase subfamily protein 0.0099 0.0382 0.1375
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0058 0.0198 0.0711
Leishmania major phosphatidylinositol 3-kinase, putative 0.0015 0.0007 0.0117
Echinococcus granulosus chromodomain helicase DNA binding protein 1 0.0033 0.0091 0.0303
Brugia malayi Protein kinase domain containing protein 0.0014 0.0006 0.0033
Trypanosoma cruzi DNA polymerase eta, putative 0.0047 0.0149 0.0264
Trypanosoma cruzi copper-transporting ATPase, putative 0.0013 0 0.0001
Loa Loa (eye worm) MH2 domain-containing protein 0.0248 0.1042 0.5099
Onchocerca volvulus 0.0066 0.0234 0.2432
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0058 0.0198 0.2057
Echinococcus granulosus Chromo domain 0.0033 0.0091 0.0303
Echinococcus multilocularis sterol regulatory element binding protein 0.0041 0.0124 0.0413
Trypanosoma brucei DNA polymerase kappa, putative 0.0055 0.0187 0.3156
Trypanosoma brucei calcium-translocating P-type ATPase 0.0076 0.0278 0.4709
Trypanosoma brucei DNA polymerase kappa, putative 0.0096 0.037 0.6255
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0058 0.0198 0.2057
Schistosoma mansoni serine/threonine protein kinase 0.0049 0.0161 0.0538
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0221 0.0923 0.1246
Brugia malayi Death domain containing protein 0.0014 0.0004 0.0022
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0018 0.0022 0.0071
Trypanosoma cruzi PAB1-binding protein , putative 0.005 0.0165 0.0294
Loa Loa (eye worm) cysteine protease 0.0055 0.0187 0.0913
Schistosoma mansoni blooms syndrome DNA helicase 0.0035 0.0099 0.0329
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0044 0.0135 0.2288
Plasmodium vivax hypothetical protein, conserved 0.0033 0.0091 0.1968
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0474 0.2044 0.7359
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0086 0.0891
Onchocerca volvulus Cathepsin L homolog 0.0055 0.0187 0.1938
Trichomonas vaginalis DNA polymerase eta, putative 0.0096 0.037 0.3841
Toxoplasma gondii LsmAD domain-containing protein 0.005 0.0165 0.0594
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0055 0.0187 0.194
Schistosoma mansoni hypothetical protein 0.005 0.0164 0.0549
Brugia malayi hypothetical protein 0.0032 0.0086 0.0482
Leishmania major cathepsin L-like protease 0.0055 0.0187 0.3159
Echinococcus multilocularis microtubule associated protein 2 0.0668 0.2907 0.9743
Brugia malayi Probable cation-transporting ATPase C10C6.6 in chromosome IV 0.0021 0.0034 0.0192
Trypanosoma cruzi copper-transporting ATPase-like protein, putative 0.0021 0.0034 0.0061
Trichomonas vaginalis Clan CA, family C1, cathepsin F-like cysteine peptidase 0.0018 0.0022 0.0227
Echinococcus granulosus Ca2 transporting ATPase plasma membrane 0.0063 0.022 0.0736
Brugia malayi cathepsin L precursor 0.0018 0.0022 0.0122
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0007 0.0072
Entamoeba histolytica cysteine protease, putative 0.0018 0.0022 0.0371
Echinococcus granulosus sterol regulatory element binding protein 0.0041 0.0124 0.0413
Loa Loa (eye worm) hypothetical protein 0.0018 0.0022 0.0107
Entamoeba histolytica cysteine proteinase, putative 0.0055 0.0187 0.3176
Mycobacterium tuberculosis Probable oxidoreductase 0.0246 0.1032 0.14
Brugia malayi Immunoglobulin I-set domain containing protein 0.0014 0.0004 0.0022
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0035 0.0097 0.1658
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0049 0.0161 0.2725
Echinococcus multilocularis lamin dm0 0.0026 0.0058 0.0193
Leishmania major P-type ATPase, putative 0.0063 0.022 0.3723
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0034 0.0091 0.0327
Echinococcus granulosus high affinity cAMP specific 3'5' cyclic 0.0058 0.0198 0.0662
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0039 0.0117 0.039
Entamoeba histolytica hypothetical protein 0.0146 0.0588 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0022 0.0227
Schistosoma mansoni Smad4 0.0017 0.0017 0.0056
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0023 0.0043 0.0594
Echinococcus multilocularis lamin 0.0026 0.0058 0.0193
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0039 0.0117 0.039
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0146 0.0591 1
Trypanosoma cruzi cytochrome P450, putative 0.0015 0.001 0.0018
Plasmodium vivax ataxin-2 like protein, putative 0.005 0.0165 0.4098
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0068 0.0246 0.1204
Echinococcus multilocularis RUN 0.0019 0.0027 0.0088
Echinococcus multilocularis dnaJ subfamily B 0.0396 0.17 0.5696
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0055 0.0187 0.194
Brugia malayi hypothetical protein 0.0146 0.0588 0.3288
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0056 0.0586
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.004 0.0119 0.1233
Mycobacterium ulcerans UDP-N-acetylglucosamine 1-carboxyvinyltransferase 0.2267 1 1
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0058 0.0198 0.2057
Onchocerca volvulus Chorion peroxidase homolog 0.0026 0.0056 0.058
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0058 0.0198 0.2057
Loa Loa (eye worm) hypothetical protein 0.0021 0.0037 0.0182
Trypanosoma brucei P-type H+-ATPase, putative 0.0042 0.0128 0.2166
Entamoeba histolytica cysteine protease, putative 0.0039 0.0117 0.1989
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0025 0.0052 0.0289
Entamoeba histolytica cation-transporting P-typeATPase, putative 0.0021 0.0034 0.0584
Echinococcus granulosus cathepsin b 0.0018 0.0022 0.0071
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0039 0.0117 0.039
Echinococcus granulosus Niemann Pick C1 protein 0.0095 0.0365 0.1222
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0022 0.0227
Entamoeba histolytica cysteine protease, putative 0.0039 0.0117 0.1989
Brugia malayi Smad1 0.0017 0.0017 0.0096
Trichomonas vaginalis DNA helicase recq, putative 0.0045 0.014 0.1458
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0046 0.0482
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0018 0.0024 0.0085
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0058 0.0198 0.2057
Loa Loa (eye worm) hypothetical protein 0.0048 0.0155 0.0757
Schistosoma mansoni terminal deoxycytidyl transferase 0.0071 0.0255 0.0855
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0018 0.0022 0.0039
Loa Loa (eye worm) hypothetical protein 0.0055 0.0187 0.0913
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0071 0.0255 0.0855
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0039 0.0116 0.2697
Brugia malayi RNA binding protein 0.0068 0.0246 0.1376
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0066 0.0236 0.0788
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0055 0.0187 0.194
Schistosoma mansoni hypothetical protein 0.0017 0.0018 0.0058
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.0107 0.1112
Echinococcus multilocularis high affinity cgmp specific 3' 5' cyclic 0.0058 0.0198 0.0662
Trypanosoma brucei DNA polymerase IV, putative 0.0096 0.037 0.6255
Loa Loa (eye worm) hypothetical protein 0.0024 0.0048 0.0237
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0034 0.0091 0.0081
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0034 0.0091 0.0162
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0033 0.0091 0.1543
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0022 0.0227
Giardia lamblia Plasma membrane calcium-transporting ATPase 2 0.0076 0.0278 0.1269
Loa Loa (eye worm) transcription factor SMAD2 0.0248 0.1042 0.5099
Entamoeba histolytica cysteine proteinase, putative 0.0039 0.0117 0.1989
Trypanosoma brucei cation-transporting ATPase, putative 0.0021 0.0034 0.0581
Trypanosoma cruzi DNA polymerase kappa, putative 0.0096 0.037 0.0657
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0049 0.0161 0.0286
Leishmania major cathepsin L-like protease 0.0055 0.0187 0.3159
Schistosoma mansoni hypothetical protein 0.0017 0.0018 0.0058
Schistosoma mansoni smad 0.0017 0.0017 0.0056
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0007 0.0072
Plasmodium falciparum ataxin-2 like protein, putative 0.005 0.0165 0.4098
Mycobacterium tuberculosis Probable reductase 0.0221 0.0923 0.1246
Schistosoma mansoni hypothetical protein 0.0019 0.0027 0.0088
Brugia malayi polk-prov protein 0.0048 0.0154 0.0859
Echinococcus multilocularis bloom syndrome protein 0.0045 0.014 0.0469
Trichomonas vaginalis MYB72, putative 0.0062 0.0216 0.224
Brugia malayi Cathepsin L-like precursor 0.0055 0.0187 0.1044
Plasmodium falciparum ataxin-2 like protein, putative 0.005 0.0165 0.4098
Loa Loa (eye worm) hypothetical protein 0.0026 0.0056 0.0273
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0058 0.0198 0.2057
Toxoplasma gondii cathepsin CPC1 0.0018 0.0022 0.0077
Trypanosoma cruzi DNA polymerase kappa, putative 0.0096 0.037 0.0657
Trypanosoma cruzi cysteine peptidase, putative 0.1282 0.563 1
Plasmodium falciparum cGMP-specific phosphodiesterase 0.0058 0.0198 0.5029
Trypanosoma brucei DNA polymerase kappa, putative 0.0077 0.0284 0.4802
Schistosoma mansoni hypothetical protein 0.0039 0.0117 0.0391
Trichomonas vaginalis chromobox protein, putative 0.0033 0.0091 0.0943
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0023 0.0043 0.0032
Brugia malayi Uncoordinated protein 44 0.0014 0.0004 0.0022
Trypanosoma brucei glucosidase, putative 0.0035 0.0097 0.1649
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0034 0.0091 0.1542
Trichomonas vaginalis PIKK family atypical protein kinase 0.0023 0.0046 0.048
Echinococcus granulosus plasma membrane calcium transporting ATPase 2 0.0076 0.0278 0.0932
Loa Loa (eye worm) hypothetical protein 0.0018 0.0022 0.0107
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0146 0.0591 1
Trichomonas vaginalis cGMP-inhibited 3,5-cyclic phosphodiesterase, putative 0.0058 0.0198 0.2057
Brugia malayi Membrane calcium atpase protein 3 0.0063 0.022 0.1231
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0058 0.0198 0.2057
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0066 0.0236 0.0788
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0058 0.0198 0.2057
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0018 0.0022 0.0227
Trichomonas vaginalis conserved hypothetical protein 0.0037 0.0106 0.1098
Echinococcus granulosus neuropeptide s receptor 0.0457 0.1969 0.6599
Plasmodium falciparum phosphodiesterase delta, putative 0.0058 0.0198 0.5029
Trichomonas vaginalis MYB3r3, putative 0.0062 0.0216 0.224
Trichomonas vaginalis ATPase, class VI, type 11C, putative 0.0021 0.0034 0.0357
Loa Loa (eye worm) hypothetical protein 0.0089 0.0337 0.1647
Schistosoma mansoni chromobox protein 0.0033 0.0091 0.0303
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0055 0.0187 0.194
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0246 0.1032 0.14
Giardia lamblia NADH oxidase lateral transfer candidate 0.0034 0.0091 0.0343
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0055 0.0187 0.194
Entamoeba histolytica Plasma membrane calcium-transporting ATPase, putative 0.0076 0.0278 0.4735
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0044 0.0135 0.2288
Brugia malayi Doublecortin family protein 0.0019 0.0027 0.015
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0202 0.0839 0.4105
Loa Loa (eye worm) sodium potassium adenosine triphosphatase 0.0029 0.007 0.0341
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0058 0.0598
Echinococcus multilocularis cathepsin b 0.0018 0.0022 0.0071
Schistosoma mansoni DNA polymerase eta 0.0095 0.0365 0.1222
Loa Loa (eye worm) cytochrome P450 family protein 0.0025 0.0055 0.0267
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0022 0.0227
Loa Loa (eye worm) calcium/calmodulin-stimulated cyclic nucleotide phosphodiesterase 0.0058 0.0198 0.0969
Loa Loa (eye worm) hypothetical protein 0.0058 0.0198 0.0969
Trypanosoma cruzi cyclic nucleotide phosphodiesterase 0.0058 0.0198 0.0352
Loa Loa (eye worm) PDE1B protein 0.0058 0.0198 0.0969
Trichomonas vaginalis ATPase, class I, type 8B, putative 0.0021 0.0034 0.0357
Leishmania major cAMP phosphodiesterase A, putative;with=GeneDB:LinJ18_V3.1100 0.0058 0.0198 0.335
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0058 0.0198 0.0711
Loa Loa (eye worm) hypothetical protein 0.0042 0.0126 0.0618
Entamoeba histolytica deoxycytidyl transferase, putative 0.0071 0.0255 0.4345
Echinococcus multilocularis Ankyrin repeat domain containing protein 0.0087 0.0328 0.1099
Loa Loa (eye worm) animal heme peroxidase 0.0026 0.0056 0.0273
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0034 0.0091 0.0162
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0014 0.0004 0.0013
Loa Loa (eye worm) hypothetical protein 0.0017 0.0018 0.0087
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0034 0.0091 0.1979
Loa Loa (eye worm) hypothetical protein 0.0021 0.0037 0.0182
Loa Loa (eye worm) hypothetical protein 0.0034 0.0092 0.0448
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0055 0.0187 0.194
Leishmania major vacuolar-type Ca2 -ATPase, putative 0.0076 0.0278 0.471
Brugia malayi haloacid dehalogenase-like hydrolase family protein 0.0037 0.0107 0.0597
Loa Loa (eye worm) hypothetical protein 0.0026 0.0056 0.0273
Trichomonas vaginalis cAMP and cAMP-inhibited cGMP 3,5-cyclic phosphodiesterase, putative 0.0058 0.0198 0.2057
Echinococcus multilocularis Smad4 0.0017 0.0017 0.0056
Plasmodium vivax vivapain-2 0.0055 0.0187 0.4707
Entamoeba histolytica cysteine protease, putative 0.0039 0.0117 0.1989
Entamoeba histolytica hypothetical protein 0.0033 0.0091 0.1543
Trypanosoma brucei cAMP phosphodiesterase A, putative 0.0058 0.0198 0.335
Trypanosoma cruzi cysteine proteinase, putative 0.0039 0.0117 0.0208
Trichomonas vaginalis calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0058 0.0198 0.2057
Toxoplasma gondii cathepsin B 0.0018 0.0022 0.0077
Trichomonas vaginalis sucrase-isomaltase, putative 0.0035 0.0097 0.1013
Onchocerca volvulus 0.0063 0.0222 0.2302
Schistosoma mansoni cathepsin s 0.0021 0.0037 0.0123
Mycobacterium ulcerans metal cation-transporting p-type ATPase F, CtpF 0.0089 0.0337 0.0327
Trypanosoma brucei DNA polymerase kappa, putative 0.0055 0.0187 0.3156
Echinococcus granulosus TGF beta signal transducer SmadC 0.0017 0.0017 0.0056
Entamoeba histolytica cysteine protease, putative 0.0039 0.0117 0.1989
Chlamydia trachomatis holo [acyl-carrier protein] synthase 0.0023 0.0043 0.0008
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0044 0.0135 0.2288
Entamoeba histolytica cysteine protease, putative 0.0039 0.0117 0.1989
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0058 0.0198 0.2057
Trichomonas vaginalis cAMP/cGMP cyclic nucleotide phosphodiesterase, putative 0.0058 0.0198 0.2057
Trichomonas vaginalis DNA helicase recq1, putative 0.0045 0.014 0.1458
Echinococcus granulosus cysteine protease 0.0039 0.0117 0.039
Trypanosoma cruzi DNA polymerase eta, putative 0.0095 0.0365 0.0648
Loa Loa (eye worm) hypothetical protein 0.0054 0.0181 0.0887
Schistosoma mansoni type V p-type atpase isoform 0.0021 0.0034 0.0114
Echinococcus multilocularis lipoxygenase domain containing protein 0.0019 0.0027 0.0088
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0058 0.0198 0.2057
Entamoeba histolytica cysteine protease, putative 0.0039 0.0117 0.1989
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0049 0.0161 0.0286
Entamoeba histolytica cysteine protease, putative 0.0018 0.0022 0.0371
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0022 0.0227
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0058 0.0198 0.2057
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0053 0.0179 0.06
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0035 0.0096 0.1622
Echinococcus granulosus Niemann Pick C1 protein 0.0136 0.0547 0.1831
Plasmodium falciparum glutathione reductase 0.0097 0.0372 1
Entamoeba histolytica plasma membrane calcium ion-transporting ATPase, putative 0.0047 0.0151 0.2565
Trypanosoma brucei PAB1-binding protein , putative 0.005 0.0165 0.2798
Schistosoma mansoni lipoxygenase 0.0053 0.0179 0.06
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0044 0.0135 0.0452
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0015 0.0007 0.0012
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0073 0.0243
Brugia malayi Probable 3',5'-cyclic phosphodiesterase R153.1, putative 0.0058 0.0198 0.1107
Echinococcus multilocularis cation transporting ATPase 13A1 0.0021 0.0034 0.0114
Plasmodium falciparum LCCL domain-containing protein 0.0019 0.0027 0.0144
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0014 0.0004 0.0013
Plasmodium vivax hypothetical protein, conserved 0.0033 0.0091 0.1968
Brugia malayi ImpB/MucB/SamB family protein 0.0071 0.0255 0.1429
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0058 0.0198 0.2057
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0058 0.0198 0.0711
Toxoplasma gondii cathepsin CPL 0.0055 0.0187 0.0671
Leishmania major DNA polymerase eta, putative 0.0047 0.0149 0.2518
Plasmodium vivax 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0058 0.0198 0.5029
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0034 0.0091 0.0162
Echinococcus multilocularis geminin 0.0686 0.2984 1
Schistosoma mansoni rab6-interacting 0.0019 0.0027 0.0088
Trypanosoma cruzi cysteine peptidase, putative 0.0039 0.0117 0.0208
Mycobacterium ulcerans DNA polymerase IV 0.0096 0.037 0.036
Loa Loa (eye worm) MH2 domain-containing protein 0.0017 0.0017 0.0084
Leishmania major DNA damage repair protein, putative 0.0022 0.0039 0.0666
Entamoeba histolytica hypothetical protein 0.0146 0.0588 1
Leishmania major calcium motive p-type ATPase, putative 0.0053 0.0176 0.2977
Loa Loa (eye worm) hypothetical protein 0.0041 0.0124 0.0605
Trichomonas vaginalis Heterochromatin protein, putative 0.0033 0.0091 0.0943
Brugia malayi CHE-14 protein 0.0041 0.0124 0.0692
Schistosoma mansoni cellular tumor antigen P53 0.0048 0.0155 0.0517
Loa Loa (eye worm) hypothetical protein 0.0037 0.0106 0.0517
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0054 0.0181 0.0887
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0091 0.0943
Echinococcus multilocularis Chromobox protein 3 0.0033 0.0091 0.0303
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0018 0.0022 0.0227
Schistosoma mansoni lamin 0.0026 0.0058 0.0193
Trypanosoma brucei unspecified product 0.009 0.0341 0.5776
Plasmodium vivax 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0058 0.0198 0.5029
Echinococcus multilocularis neuropeptide s receptor 0.0457 0.1969 0.6599
Brugia malayi Probable calcium-transporting ATPase KIAA0703 0.0055 0.0185 0.1033
Giardia lamblia DINP protein human, muc B family 0.0077 0.0284 0.1296
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0053 0.0179 0.06
Loa Loa (eye worm) hypothetical protein 0.0229 0.0958 0.4688
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0033 0.0091 0.0325
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0096 0.0994
Plasmodium falciparum copper-transporting ATPase 0.0021 0.0034 0.0358
Brugia malayi Probable 3',5'-cyclic phosphodiesterase R153.1, putative 0.0416 0.1788 1
Brugia malayi CXXC zinc finger family protein 0.0028 0.0066 0.0367
Leishmania major cathepsin L-like protease 0.0146 0.0591 1
Leishmania major phosphopantetheinyl transferase-like protein 0.0023 0.0043 0.0721
Schistosoma mansoni na+/k+ atpase alpha subunit 0.0053 0.0176 0.0588
Trypanosoma brucei vacuolar-type Ca2+-ATPase, putative 0.0076 0.0278 0.471
Treponema pallidum cation-transporting ATPase, P-type 0.0021 0.0034 0.0034
Leishmania major cathepsin L-like protease 0.0146 0.0591 1
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.004 0.0119 0.1233
Onchocerca volvulus 0.0055 0.0187 0.1938
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0047 0.0149 0.0835
Trypanosoma brucei unspecified product 0.0049 0.0158 0.2677
Trichomonas vaginalis cation-transporting ATPase, putative 0.0089 0.0337 0.3497
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0055 0.0187 0.194
Trypanosoma cruzi plasma-membrane proton-efflux P-type ATPase, putative 0.0029 0.007 0.0124
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0049 0.0161 0.0578
Schistosoma mansoni cathepsin F (C01 family) 0.0055 0.0187 0.0624
Trypanosoma cruzi cysteine peptidase, putative 0.0055 0.0187 0.0332
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.0076 0.0278 0.2892
Schistosoma mansoni cpg binding protein 0.0029 0.0073 0.0242
Echinococcus granulosus plasma membrane calcium transporting ATPase 0.0063 0.022 0.0736
Schistosoma mansoni tar DNA-binding protein 0.0068 0.0246 0.0823
Trypanosoma cruzi copper-transporting ATPase-like protein, putative 0.0021 0.0034 0.0061
Trypanosoma cruzi cysteine peptidase, putative 0.0146 0.0591 0.105
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0058 0.0198 0.2057
Schistosoma mansoni hypothetical protein 0.0686 0.2984 1
Trichomonas vaginalis CMGC family protein kinase 0.0049 0.0161 0.1673
Echinococcus multilocularis X box binding protein 1 0.0279 0.118 0.3954
Schistosoma mansoni cathepsin C 0.0018 0.0022 0.0071
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0054 0.0181 0.1014
Echinococcus multilocularis musashi 0.0026 0.0058 0.0193
Schistosoma mansoni cathepsin S (C01 family) 0.0018 0.0022 0.0071
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0018 0.0022 0.0227
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0091 0.0943
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0058 0.0198 0.0662
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0022 0.0227
Toxoplasma gondii NADPH-glutathione reductase 0.0034 0.0091 0.0327
Echinococcus multilocularis sarco:endoplasmic reticulum calcium ATPase 0.0089 0.0337 0.1127
Loa Loa (eye worm) hypothetical protein 0.0021 0.0034 0.0168
Trichomonas vaginalis CMGC family protein kinase 0.0049 0.0161 0.1673
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0034 0.0091 0.0304
Echinococcus granulosus chromobox protein 1 0.0148 0.06 0.2009
Loa Loa (eye worm) hypothetical protein 0.0095 0.0365 0.1786
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0033 0.0091 0.1543
Leishmania major calcium-transporting ATPase, putative 0.0053 0.0176 0.2977
Trypanosoma cruzi copper-transporting ATPase-like protein, putative 0.0013 0 0.0001
Trypanosoma cruzi major cysteine proteinase, putative 0.0109 0.0426 0.0757
Schistosoma mansoni cation-transporting atpase worm 0.0021 0.0034 0.0114
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.0097 0.1013
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0017 0.0017 0.0056
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0058 0.0198 0.0711
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0023 0.0043 0.0152
Entamoeba histolytica cysteine protease, putative 0.0039 0.0117 0.1989
Loa Loa (eye worm) hypothetical protein 0.003 0.0073 0.0358
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0058 0.0198 0.2057
Loa Loa (eye worm) hypothetical protein 0.0039 0.0114 0.0557
Echinococcus granulosus Chromobox protein 3 0.0033 0.0091 0.0303
Loa Loa (eye worm) animal heme peroxidase 0.0026 0.0056 0.0273
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0018 0.0024 0.0079
Trichomonas vaginalis chromobox protein, putative 0.0094 0.0358 0.3721
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0035 0.0097 0.0477
Echinococcus granulosus RUN 0.0019 0.0027 0.0088
Toxoplasma gondii histone lysine methyltransferase SET1 0.0054 0.0181 0.0649
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0018 0.0024 0.0079
Schistosoma mansoni chromobox protein 0.0148 0.06 0.2009
Loa Loa (eye worm) hypothetical protein 0.0026 0.0056 0.0273
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0036 0.0104 0.1077
Loa Loa (eye worm) CYP4Cod1 0.0015 0.001 0.005
Trypanosoma cruzi cytochrome P450, putative 0.0015 0.001 0.0018
Brugia malayi MH1 domain containing protein 0.0017 0.0017 0.0096
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0018 0.0022 0.0071
Schistosoma mansoni cpg binding protein 0.0029 0.0073 0.0242
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.0058 0.0198 0.0662
Onchocerca volvulus 0.0019 0.0027 0.0279
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0026 0.0058 0.0284
Plasmodium vivax vivapain-3 0.0039 0.0117 0.2716
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0035 0.0096 0.1622
Loa Loa (eye worm) calcium-transporting ATPase sarcoplasmic/endoplasmic reticulum type 0.0055 0.0185 0.0903
Leishmania major cathepsin L-like protease 0.0055 0.0187 0.3159
Schistosoma mansoni alpha-glucosidase 0.0136 0.0545 0.1824
Brugia malayi Cathepsin L-like precursor 0.0021 0.0037 0.0208
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0095 0.0365 0.6211
Brugia malayi Cathepsin L-like precursor 0.0034 0.0092 0.0512
Onchocerca volvulus Peroxidase homolog 0.0026 0.0056 0.058
Trypanosoma cruzi plasma membrane Ca2+ ATPase 0.0076 0.0278 0.0494
Trichomonas vaginalis PIKK family atypical protein kinase 0.0023 0.0046 0.048
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0018 0.0024 0.0134
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0049 0.0161 0.0286
Loa Loa (eye worm) cathepsin B 0.0018 0.0022 0.0107
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0055 0.0187 0.194
Trypanosoma cruzi P-type H+-ATPase, putative 0.0042 0.0128 0.0227
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.0076 0.0278 0.2892
Trypanosoma brucei DNA damage repair protein, putative 0.0022 0.0039 0.0666
Brugia malayi cathepsin F-like cysteine proteinase 0.0021 0.0037 0.0208
Echinococcus granulosus calcium transporting ATPase type 2C member 0.0089 0.0337 0.1127
Brugia malayi intermediate filament protein 0.0026 0.0058 0.0324
Trypanosoma brucei chrX additional, unordered contigs 0.0022 0.0039 0.0666
Brugia malayi Associated with TFs and helicases family protein 0.0033 0.0091 0.0507
Trypanosoma brucei DNA polymerase kappa, putative 0.0096 0.037 0.6255
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.0097 0.1013
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0049 0.0161 0.0788
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.003 0.0076 0.1552
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0055 0.0187 0.194
Trypanosoma cruzi DNA damage repair protein, putative 0.0022 0.0039 0.007
Schistosoma mansoni ATPase 0.0089 0.0337 0.1127
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0077 0.0284 0.4802
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0023 0.0043 0.0152
Echinococcus granulosus cathepsin l1 0.0034 0.0092 0.0305
Brugia malayi Calcium-transporting ATPase sarcoplasmic/endoplasmic reticulum type 0.0076 0.0278 0.1556
Entamoeba histolytica myb-like DNA-binding domain containing protein 0.0062 0.0216 0.3668
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0018 0.0022 0.0071
Giardia lamblia Hypothetical protein 0.0058 0.0198 0.0871
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0072 0.0744
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0096 0.0994
Echinococcus granulosus dual 3'5' cyclic AMP and GMP phosphodiesterase 0.0058 0.0198 0.0662
Brugia malayi Glycosyl hydrolases family 31 protein 0.0035 0.0097 0.0545
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0034 0.0091 0.1542
Loa Loa (eye worm) hypothetical protein 0.0034 0.0092 0.0448
Loa Loa (eye worm) thioredoxin reductase 0.0097 0.0372 0.1821
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0058 0.0198 0.0662
Loa Loa (eye worm) hypothetical protein 0.0026 0.0056 0.0273
Loa Loa (eye worm) hypothetical protein 0.0026 0.0056 0.0273
Trypanosoma cruzi cysteine peptidase, putative 0.0146 0.0591 0.105
Giardia lamblia Plasma membrane calcium-transporting ATPase 2 0.0053 0.0176 0.0762
Echinococcus granulosus histone lysine methyltransferase setb 0.003 0.0073 0.0243
Brugia malayi Blistered cuticle protein 3 0.0026 0.0056 0.0313
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0058 0.0198 0.2057
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0086 0.0891
Loa Loa (eye worm) hypothetical protein 0.0033 0.0091 0.0444
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0058 0.0198 0.2057
Brugia malayi SET domain containing protein 0.0035 0.0098 0.0549
Trypanosoma brucei cysteine peptidase C (CPC) 0.0018 0.0022 0.0369
Echinococcus multilocularis chromodomain helicase DNA binding protein 1 0.0033 0.0091 0.0303
Brugia malayi E1-E2 ATPase family protein 0.0021 0.0034 0.0192
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0039 0.0117 0.0208
Trichomonas vaginalis r2r3-MYB transcription factor, putative 0.0062 0.0216 0.224
Echinococcus granulosus calcium:calmodulin dependent 3'5' cyclic 0.0058 0.0198 0.0662
Trichomonas vaginalis r2r3-MYB transcription factor, putative 0.0062 0.0217 0.2254
Brugia malayi Type III restriction enzyme, res subunit family protein 0.0033 0.0091 0.0507
Plasmodium vivax heterochromatin protein 1, putative 0.0033 0.0091 0.1968
Echinococcus granulosus neutral alpha glucosidase AB 0.0035 0.0097 0.0325
Onchocerca volvulus 0.0047 0.0149 0.1551
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0022 0.0227
Schistosoma mansoni DNA helicase recq5 0.0018 0.0024 0.0079
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.0018 0.0022 0.0071
Brugia malayi Animal haem peroxidase family protein 0.0026 0.0056 0.0313
Toxoplasma gondii chromodomain helicase DNA binding protein CHD1/SWI2/SNF2 0.0033 0.0091 0.0325
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0017 0.0018 0.0058
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.0076 0.0278 0.2892
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0018 0.0022 0.0071
Trypanosoma cruzi cysteine proteinase, putative 0.0039 0.0117 0.0208
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0044 0.0135 0.2288
Trypanosoma cruzi cAMP phosphodiesterase A, putative 0.0058 0.0198 0.0352
Echinococcus multilocularis chromobox protein 1 0.0148 0.06 0.2009
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0058 0.0198 0.2057
Treponema pallidum NADH oxidase 0.0034 0.0091 0.0091
Echinococcus multilocularis mitogen activated protein kinase 0.0049 0.0161 0.0538
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0096 0.0994
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0055 0.0187 0.0913
Echinococcus multilocularis calcium:calmodulin dependent 3',5' cyclic 0.0058 0.0198 0.0662
Echinococcus granulosus lysosomal alpha glucosidase 0.0158 0.0642 0.2151
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.0474 0.2044 0.685
Echinococcus multilocularis Ca2+ transporting ATPase plasma membrane 0.0063 0.022 0.0736
Entamoeba histolytica cysteine protease, putative 0.0055 0.0187 0.3176
Trypanosoma cruzi cysteine peptidase, putative 0.0146 0.0591 0.105
Schistosoma mansoni lamin 0.0026 0.0058 0.0193
Trypanosoma cruzi calcium-translocating P-type ATPase, putative 0.0047 0.0151 0.0268
Trypanosoma cruzi PAB1-binding protein , putative 0.005 0.0165 0.0294
Echinococcus multilocularis tar DNA binding protein 0.0068 0.0246 0.0823
Loa Loa (eye worm) sodium/potassium-transporting ATPase subunit alpha 0.0045 0.0141 0.0688
Plasmodium falciparum heterochromatin protein 1 0.0033 0.0091 0.1968
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0044 0.0135 0.024
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0023 0.0043 0.0012
Echinococcus granulosus peroxidasin 0.0026 0.0056 0.0186
Loa Loa (eye worm) calcium ATPase 0.0018 0.002 0.0099
Trichomonas vaginalis conserved hypothetical protein 0.0088 0.0332 0.3452
Brugia malayi Papain family cysteine protease containing protein 0.0039 0.0117 0.0654
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0058 0.0198 0.2057
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0125 0.0496 0.0881
Trypanosoma cruzi P-type H+-ATPase, putative 0.0029 0.007 0.0124
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0018 0.0022 0.0071
Trichomonas vaginalis conserved hypothetical protein 0.0058 0.0198 0.2057
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0146 0.0588 0.1969
Mycobacterium tuberculosis Probable UDP-N-acetylglucosamine 1-carboxyvinyltransferase MurA 0.1628 0.7165 1
Echinococcus granulosus Polycystic kidney disease protein 0.0019 0.0027 0.0088
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0015 0.0007 0.0022
Schistosoma mansoni loxhd1 0.0019 0.0027 0.0088
Plasmodium falciparum chromodomain-helicase-DNA-binding protein 1 homolog, putative 0.0033 0.0091 0.1968
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0058 0.0198 0.0711
Entamoeba histolytica hypothetical protein 0.0018 0.0022 0.0371
Schistosoma mansoni tar DNA-binding protein 0.0068 0.0246 0.0823
Plasmodium falciparum cysteine proteinase falcipain 1 0.0039 0.0117 0.2716
Loa Loa (eye worm) phosphatidylinositol 3 0.0044 0.0135 0.0662
Trypanosoma cruzi target of rapamycin kinase 3 0.0035 0.0096 0.017
Brugia malayi cahepsin L-like non-peptiedase homolog 0.0018 0.0022 0.0122
Leishmania major DNA polymerase eta, putative 0.0095 0.0365 0.6174
Trypanosoma cruzi cysteine protease, putative 0.0039 0.0117 0.0208
Echinococcus granulosus copper transporting ATPase 1 0.0021 0.0034 0.0114
Echinococcus granulosus geminin 0.0686 0.2984 1
Echinococcus multilocularis Niemann Pick C1 protein 0.0136 0.0547 0.1831
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0058 0.0598
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0049 0.0161 0.2725
Schistosoma mansoni alpha-glucosidase 0.0136 0.0545 0.1824
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0024 0.0048 0.0085
Loa Loa (eye worm) hypothetical protein 0.0018 0.0022 0.0107
Echinococcus multilocularis plasma membrane calcium transporting ATPase 0.0063 0.022 0.0736
Trypanosoma cruzi hypothetical protein, conserved 0.0022 0.0039 0.007
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0021 0.0037 0.0182
Echinococcus granulosus Protein patched homolog 1 0.0041 0.0124 0.0413
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0017 0.0018 0.0058
Brugia malayi Cathepsin L-like precursor 0.0055 0.0187 0.1044
Echinococcus granulosus cathepsin b 0.0018 0.0022 0.0071
Onchocerca volvulus 0.0026 0.0056 0.058
Leishmania major alpha glucosidase II subunit, putative 0.0035 0.0097 0.1649
Trypanosoma cruzi hypothetical protein, conserved 0.0058 0.0198 0.0352
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0015 0.0007 0.0117
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.0018 0.0022 0.0071
Schistosoma mansoni smad1 5 8 and 0.0017 0.0017 0.0056
Echinococcus granulosus cation transporting ATPase 13A3 0.0021 0.0034 0.0114
Mycobacterium leprae conserved hypothetical protein 0.0023 0.0043 0.0012
Brugia malayi Glycosyl hydrolases family 31 protein 0.0158 0.0642 0.3591
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0044 0.0135 0.0756
Onchocerca volvulus 0.0055 0.0187 0.1938
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0044 0.0135 0.0452
Trichomonas vaginalis DNA helicase recq, putative 0.0024 0.0048 0.0499
Plasmodium falciparum thioredoxin reductase 0.0097 0.0372 1
Mycobacterium ulcerans metal cation transporter p-type ATPase a 0.0066 0.0234 0.0224
Loa Loa (eye worm) Na,K-ATPase alpha subunit 0.0066 0.0234 0.1146
Echinococcus granulosus calcium:calmodulin dependent 3'5' cyclic 0.0058 0.0198 0.0662
Schistosoma mansoni hypothetical protein 0.0279 0.118 0.3954
Echinococcus granulosus intermediate filament protein 0.0026 0.0058 0.0193
Loa Loa (eye worm) hypothetical protein 0.0021 0.0037 0.0182
Echinococcus granulosus tar DNA binding protein 0.0068 0.0246 0.0823
Schistosoma mansoni calcium/calmodulin-dependent 35-cyclic nucleotide phosphodiesterase 0.0058 0.0198 0.0662
Loa Loa (eye worm) CHromoDomain protein family member 0.0035 0.0098 0.0478
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0055 0.0187 0.194
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0124 0.1285
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0034 0.0091 0.0162
Leishmania major cathepsin L-like protease 0.0055 0.0187 0.3159
Trichomonas vaginalis chromobox protein, putative 0.0033 0.0091 0.0943
Brugia malayi Cathepsin L-like cysteine proteinase 0.0034 0.0092 0.0512
Loa Loa (eye worm) hypothetical protein 0.0033 0.0091 0.0444
Plasmodium vivax unspecified product 0.0039 0.0117 0.2716
Trichomonas vaginalis conserved hypothetical protein 0.0058 0.0198 0.2057
Loa Loa (eye worm) hypothetical protein 0.0026 0.0056 0.0273
Loa Loa (eye worm) hypothetical protein 0.0066 0.0236 0.1153
Brugia malayi Animal haem peroxidase family protein 0.0026 0.0056 0.0313
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.003 0.0073 0.0262
Brugia malayi Papain family cysteine protease containing protein 0.0018 0.0022 0.0122
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0058 0.0198 0.0352
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0071 0.0255 0.0855
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0034 0.0091 0.0081
Mycobacterium tuberculosis Probable metal cation transporter P-type ATPase A CtpF 0.0023 0.0045 0.0014
Loa Loa (eye worm) TAR-binding protein 0.0068 0.0246 0.1204
Brugia malayi Intermediate filament tail domain containing protein 0.0026 0.0058 0.0324
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.0474 0.2044 0.685
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0146 0.0591 1
Onchocerca volvulus 0.0019 0.0027 0.0279
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0035 0.0098 0.0326
Giardia lamblia Potassium-transporting ATPase alpha chain 1 0.0053 0.0176 0.0762
Brugia malayi chromobox protein homolog 3 0.0088 0.0332 0.1858
Plasmodium falciparum cysteine proteinase falcipain 3 0.0055 0.0187 0.4707
Schistosoma mansoni netrin receptor unc5 0.0014 0.0004 0.0012
Mycobacterium ulcerans cation transporter p-type ATPase a CtpA 0.0021 0.0034 0.0024
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.004 0.0119 0.1233
Leishmania major cAMP-specific phosphodiesterase, putative 0.0058 0.0198 0.335
Trypanosoma brucei DNA polymerase IV, putative 0.0096 0.037 0.6255
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0096 0.037 0.3841
Plasmodium vivax multidomain scavenger receptor, putative 0.0019 0.0027 0.0144
Loa Loa (eye worm) hypothetical protein 0.0026 0.0056 0.0273
Schistosoma mansoni peroxidasin 0.0026 0.0056 0.0186
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0018 0.0024 0.0079
Plasmodium falciparum 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0058 0.0198 0.5029
Toxoplasma gondii thioredoxin reductase 0.0097 0.0372 0.1338
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0088 0.0332 0.345
Leishmania major vacuolar-type Ca2 -ATPase, putative 0.0076 0.0278 0.471
Brugia malayi calcium ATPase 0.0029 0.007 0.039
Entamoeba histolytica hypothetical protein 0.0023 0.0043 0.0725
Echinococcus granulosus death domain containing protein 0.0014 0.0004 0.0012
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.0097 0.1013

Activities

Activity type Activity value Assay description Source Reference
%max (functional) = 64 % Agonist activity at recombinant BRS-3 receptor expressed in baculovirus-transduced HEK293 cells assessed as maximum response of intracellular calcium mobilization by FLIPR assay relative to D-Phe-Gln-Trp-Ala-Val-beta-Ala-His-Phe-Nle-NH2 ChEMBL. 18818070
Activity (ADMET) Aryl hydrocarbon receptor antagonist (species not specified) ChEMBL. No reference
Control (binding) = 99 % Urease activity in wild type H pylori, CCUG 15818, at 100 uM ChEMBL. 8523404
Control (binding) = 101 % Urease activity in H pylori, CCUG 15818, at 10 uM ChEMBL. 8523404
Control (binding) = 109 % Urease activity was determined in wild type-H pylori, CCUG 15818, at a concentration of 1 uM ChEMBL. 8523404
EC50 (functional) = 3900 nM Agonist activity at recombinant BRS-3 receptor expressed in baculovirus-transduced HEK293 cells assessed as intracellular calcium mobilization by FLIPR assay ChEMBL. 18818070
Log Ko = 0 Lipophilicity (log Ko) ChEMBL. 9599229
MBC (functional) = 32 ug ml-1 Antibacterial activity against Helicobacter pylori strain. ChEMBL. 9599229

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

3 literature references were collected for this gene.

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