Detailed information for compound 74265

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 707.763 | Formula: C38H45NO12
  • H donors: 0 H acceptors: 2 LogP: 6.66 Rotable bonds: 19
    Rule of 5 violations (Lipinski): 2
  • SMILES: COC(=O)c1n(CCCCc2ccc(c(c2)OC)OC)c(c(c1c1cc(OC)c(c(c1)OC)OC)c1cc(OC)c(c(c1)OC)OC)C(=O)OC
  • InChi: 1S/C38H45NO12/c1-42-25-15-14-22(17-26(25)43-2)13-11-12-16-39-33(37(40)50-9)31(23-18-27(44-3)35(48-7)28(19-23)45-4)32(34(39)38(41)51-10)24-20-29(46-5)36(49-8)30(21-24)47-6/h14-15,17-21H,11-13,16H2,1-10H3
  • InChiKey: JFRIRXGATFHCCD-UHFFFAOYSA-N  

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity

Obtained from network model

Ranking Plot


Putative Targets List


Species Potential target Raw Global Species
Trypanosoma cruzi cysteine peptidase, putative 0.0148 0.0588 0.1044
Brugia malayi Cathepsin L-like cysteine proteinase 0.0034 0.0088 0.0504
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.0057 0.0188 0.1961
Schistosoma mansoni rab6-interacting 0.0019 0.0023 0.006
Plasmodium falciparum heterochromatin protein 1 0.0034 0.0087 0.1422
Onchocerca volvulus Peroxidasin homolog 0.0026 0.0052 0.0541
Brugia malayi hypothetical protein 0.012 0.0465 0.2669
Loa Loa (eye worm) transcription factor SMAD2 0.0388 0.1639 0.8226
Loa Loa (eye worm) ctsf protein 0.0056 0.0183 0.0918
Echinococcus multilocularis cathepsin L 0.0018 0.0018 0.0047
Plasmodium falciparum serine repeat antigen 1 0.0018 0.0018 0.0293
Schistosoma mansoni serine/threonine protein kinase 0.005 0.0157 0.041
Echinococcus multilocularis phosphoserine phosphatase 0.0017 0.0011 0.0028
Leishmania major hypothetical protein, conserved 0.0057 0.0188 0.2709
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0018 0.0018 0.031
Echinococcus granulosus calcium:calmodulin dependent 3'5' cyclic 0.0057 0.0188 0.0491
Mycobacterium ulcerans metal cation transporter p-type ATPase, CtpV 0.0026 0.0053 0.0053
Trypanosoma cruzi cysteine protease, putative 0.004 0.0113 0.0201
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0015 0.0003 0.0005
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.0087 0.0905
Loa Loa (eye worm) animal heme peroxidase 0.0026 0.0052 0.0261
Entamoeba histolytica cysteine protease, putative 0.0018 0.0018 0.031
Echinococcus granulosus mitogen activated protein kinase 0.005 0.0157 0.041
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0053 0.0171 0.2803
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.0411 0.1742 0.4545
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.005 0.0157 0.2264
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0044 0.0131 0.0343
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0064 0.0218 0.0569
Loa Loa (eye worm) hypothetical protein 0.0026 0.0052 0.0261
Plasmodium vivax unspecified product 0.0018 0.0018 0.0293
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0143 0.0566 0.5901
Trichomonas vaginalis alpha-galactosidase/alpha-N-acetylgalactosaminidase, putative 0.0067 0.0232 0.2417
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0092 0.0957
Giardia lamblia Cathepsin B precursor 0.0018 0.0018 0.009
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0014 0 0.0002
Loa Loa (eye worm) hypothetical protein 0.0017 0.0012 0.0061
Loa Loa (eye worm) hypothetical protein 0.0057 0.0188 0.0945
Trypanosoma cruzi proton motive ATPase 1, putative 0.0017 0.0011 0.0019
Plasmodium falciparum cGMP-specific phosphodiesterase 0.0057 0.0188 0.3081
Trypanosoma cruzi trypanothione reductase, putative 0.0053 0.0171 0.0304
Trypanosoma cruzi hypothetical protein, conserved 0.0057 0.0188 0.0334
Trypanosoma brucei cytochrome P450, putative 0.0016 0.0006 0.009
Brugia malayi Membrane calcium atpase protein 3 0.0077 0.0274 0.1572
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0014 0.0000033761 0.0000088073
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0057 0.0188 0.0678
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0019 0.002 0.0052
Leishmania major cathepsin L-like protease 0.0056 0.0183 0.2633
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0039 0.0109 0.0628
Echinococcus multilocularis Smad4 0.0026 0.0054 0.0141
Schistosoma mansoni Smad4 0.0026 0.0054 0.0141
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0067 0.0232 0.0605
Leishmania major proton motive ATPase, putative 0.0026 0.0053 0.0765
Onchocerca volvulus Peroxidasin homolog 0.0026 0.0052 0.0541
Schistosoma mansoni na+/k+ atpase alpha subunit 0.0066 0.023 0.0599
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0035 0.0094 0.047
Plasmodium vivax unspecified product 0.0022 0.0033 0.0546
Entamoeba histolytica cysteine protease, putative 0.0018 0.0018 0.031
Leishmania major DNA damage repair protein, putative 0.0036 0.0098 0.1405
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0056 0.0183 0.1906
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0056 0.0183 0.1906
Echinococcus multilocularis sterol regulatory element binding protein 0.0041 0.012 0.0313
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0018 0.0018 0.0047
Loa Loa (eye worm) hypothetical protein 0.0061 0.0208 0.1043
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0057 0.0188 0.1961
Loa Loa (eye worm) hypothetical protein 0.0036 0.0098 0.0492
Loa Loa (eye worm) sodium/potassium-transporting ATPase subunit alpha 0.0056 0.0186 0.0932
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0019 0.002 0.0052
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0082 0.0853
Entamoeba histolytica cysteine protease, putative 0.004 0.0113 0.196
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.0087 0.0905
Trichomonas vaginalis glutathione reductase, putative 0.0053 0.0171 0.1784
Schistosoma mansoni cathepsin F (C01 family) 0.0056 0.0183 0.0477
Schistosoma mansoni cathepsin F (C01 family) 0.0034 0.0088 0.0229
Trypanosoma brucei DNA polymerase IV, putative 0.0143 0.0566 0.815
Plasmodium falciparum cysteine proteinase falcipain 1 0.004 0.0113 0.1852
Toxoplasma gondii cathepsin CPC1 0.0018 0.0018 0.0064
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.005 0.0157 0.0279
Entamoeba histolytica cysteine protease, putative 0.004 0.0113 0.196
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0057 0.0188 0.0678
Echinococcus granulosus phospholipid transporting ATPase VA 0.0017 0.0011 0.0028
Brugia malayi Na,K-ATPase alpha subunit 0.0083 0.0302 0.1736
Leishmania major cathepsin L-like protease 0.0148 0.0588 0.8458
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0053 0.0547
Loa Loa (eye worm) hypothetical protein 0.0026 0.0052 0.0261
Trypanosoma brucei hypothetical protein, conserved 0.0036 0.0098 0.1405
Brugia malayi cathepsin F-like cysteine proteinase 0.0018 0.0018 0.0103
Trypanosoma cruzi Calcium ATPase SERCA-like 0.0118 0.0455 0.0808
Entamoeba histolytica hypothetical protein 0.0023 0.0039 0.0671
Giardia lamblia Cathepsin B precursor 0.0018 0.0018 0.009
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0042 0.0441
Trypanosoma brucei 3', 5'-cyclic nucleotide phosphodiesterase, putative 0.0057 0.0188 0.2709
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0042 0.0441
Loa Loa (eye worm) hypothetical protein 0.0018 0.0018 0.009
Schistosoma mansoni transcription factor LCR-F1 0.0146 0.0577 0.1505
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0024 0.0044 0.0635
Brugia malayi MH1 domain containing protein 0.0015 0.0002 0.0013
Loa Loa (eye worm) hypothetical protein 0.0468 0.1992 1
Trypanosoma cruzi cation-transporting ATPase, putative 0.0026 0.0053 0.0094
Giardia lamblia Cathepsin B precursor 0.0018 0.0018 0.009
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0023 0.0039 0.0634
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0056 0.0183 0.1906
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0056 0.0183 0.1906
Schistosoma mansoni tar DNA-binding protein 0.0068 0.0235 0.0613
Trichomonas vaginalis r2r3-MYB transcription factor, putative 0.006 0.02 0.2088
Loa Loa (eye worm) latrophilin receptor protein 2 0.0017 0.0012 0.0061
Entamoeba histolytica hypothetical protein 0.0034 0.0087 0.1506
Loa Loa (eye worm) phosphatidylinositol 3 0.0044 0.0131 0.066
Trypanosoma brucei P-type H+-ATPase, putative 0.0053 0.017 0.2446
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0067 0.0232 0.0605
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.0468 0.1992 0.5197
Brugia malayi glutathione reductase 0.0153 0.0611 0.3505
Loa Loa (eye worm) hypothetical protein 0.0014 0.0001 0.0003
Chlamydia trachomatis phosphoshikimate 1-carboxyl vinyltransferase 0.0647 0.2775 0.2775
Toxoplasma gondii phospholipid-translocating P-type ATPase, flippase subfamily protein 0.0017 0.0011 0.0039
Echinococcus granulosus neutral alpha glucosidase AB 0.0035 0.0094 0.0244
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0124 0.048 0.067
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0031 0.0072 0.1183
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0057 0.0188 0.0678
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0057 0.0188 0.0678
Echinococcus granulosus lamin dm0 0.0026 0.0054 0.0141
Trypanosoma cruzi cysteine peptidase, putative 0.0148 0.0588 0.1044
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0098 0.0173
Leishmania major cathepsin L-like protease 0.0148 0.0588 0.8458
Trichomonas vaginalis MYB3r3, putative 0.006 0.0199 0.2075
Schistosoma mansoni hypothetical protein 0.0017 0.0012 0.0032
Echinococcus granulosus apoptosis inducing factor 1 mitochondrial 0.0014 0.0000033761 0.0000088073
Schistosoma mansoni hypothetical protein 0.0017 0.0012 0.0032
Entamoeba histolytica cysteine protease, putative 0.004 0.0113 0.196
Trichomonas vaginalis ATPase, class I, type 8B, putative 0.0026 0.0053 0.0554
Entamoeba histolytica plasma membrane calcium ion-transporting ATPase, putative 0.0057 0.0188 0.3251
Brugia malayi cathepsin L-like precursor 0.0034 0.0088 0.0504
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0044 0.0131 0.1891
Loa Loa (eye worm) hypothetical protein 0.012 0.0465 0.2334
Echinococcus granulosus chromodomain helicase DNA binding protein 1 0.0034 0.0087 0.0227
Loa Loa (eye worm) hypothetical protein 0.0022 0.0033 0.0168
Entamoeba histolytica recQ family helicase, putative 0.0024 0.0044 0.0765
Toxoplasma gondii P-type ATPase PMA1 0.0053 0.017 0.0613
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0053 0.0171 0.0171
Schistosoma mansoni DNA helicase recq5 0.0019 0.002 0.0052
Entamoeba histolytica hypothetical protein 0.0146 0.0577 1
Loa Loa (eye worm) hypothetical protein 0.0311 0.1302 0.6537
Toxoplasma gondii chromodomain helicase DNA binding protein CHD1/SWI2/SNF2 0.0034 0.0087 0.0313
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0098 0.0368 0.096
Entamoeba histolytica cysteine proteinase, putative 0.004 0.0113 0.196
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0082 0.0853
Trichomonas vaginalis PIKK family atypical protein kinase 0.0044 0.0131 0.1369
Trypanosoma brucei hypothetical protein, conserved 0.0036 0.0098 0.1405
Brugia malayi hypothetical protein 0.0017 0.0011 0.0063
Loa Loa (eye worm) PDE1B protein 0.0057 0.0188 0.0945
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0053 0.0171 0.0171
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0057 0.0188 0.1961
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0068 0.0235 0.118
Loa Loa (eye worm) hypothetical protein 0.0018 0.0018 0.009
Brugia malayi Sodium/potassium-transporting ATPase alpha chain, putative 0.0056 0.0186 0.1065
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0017 0.0012 0.007
Schistosoma mansoni tar DNA-binding protein 0.0068 0.0235 0.0613
Plasmodium falciparum dipeptidyl aminopeptidase 2 0.0018 0.0018 0.0293
Schistosoma mansoni calcium/calmodulin-dependent 35-cyclic nucleotide phosphodiesterase 0.0057 0.0188 0.0491
Trichomonas vaginalis cAMP and cAMP-inhibited cGMP 3,5-cyclic phosphodiesterase, putative 0.0057 0.0188 0.1961
Echinococcus granulosus Ankyrin repeat domain containing protein 0.0088 0.0325 0.0847
Echinococcus granulosus Niemann Pick C1 protein 0.0097 0.0362 0.0943
Trypanosoma brucei calcium motive p-type ATPase, putative 0.0066 0.023 0.3306
Echinococcus granulosus Protein patched homolog 1 0.0041 0.012 0.0313
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.0087 0.0905
Echinococcus granulosus GPCR family 2 0.0017 0.0012 0.0032
Schistosoma mansoni lamin 0.0026 0.0054 0.0141
Schistosoma mansoni cation-transporting atpase worm 0.0026 0.0053 0.0139
Toxoplasma gondii heavy metal translocating P-type ATPase subfamily protein 0.0026 0.0053 0.0191
Loa Loa (eye worm) cyclic AMP specific phosphodiesterase PDE4D5A 0.0411 0.1742 0.8745
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.01 0.0379 0.0988
Trypanosoma cruzi hypothetical protein, conserved 0.0057 0.0188 0.0334
Leishmania major cathepsin L-like protease 0.0148 0.0588 0.8458
Trypanosoma brucei DNA polymerase kappa, putative 0.0062 0.0212 0.3051
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0036 0.0094 0.0245
Loa Loa (eye worm) hypothetical protein 0.0026 0.0052 0.0261
Onchocerca volvulus Peroxidase homolog 0.0026 0.0052 0.0541
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0057 0.0188 0.1961
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0034 0.0087 0.1506
Schistosoma mansoni peroxidasin 0.0026 0.0052 0.0136
Trypanosoma brucei DNA damage repair protein, putative 0.0036 0.0098 0.1405
Plasmodium falciparum glutathione reductase 0.0153 0.0611 1
Loa Loa (eye worm) hypothetical protein 0.0026 0.0052 0.0261
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.0057 0.0188 0.0491
Plasmodium falciparum phosphodiesterase delta, putative 0.0057 0.0188 0.3081
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0053 0.0171 0.0447
Brugia malayi Pre-SET motif family protein 0.003 0.0069 0.0397
Plasmodium falciparum chromodomain-helicase-DNA-binding protein 1 homolog, putative 0.0034 0.0087 0.1422
Trypanosoma cruzi cruzipain precursor, putative 0.0148 0.0588 0.1044
Echinococcus granulosus pyridine nucleotide disulfide oxidoreductase 0.0014 0.0000033761 0.0000088073
Trypanosoma cruzi P-type H+-ATPase, putative 0.0053 0.017 0.0302
Brugia malayi Cathepsin L-like precursor 0.0056 0.0183 0.105
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0019 0.002 0.0101
Onchocerca volvulus 0.0122 0.0473 0.4931
Plasmodium vivax glutathione reductase, putative 0.0153 0.0611 1
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0026 0.0054 0.0141
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.0094 0.0976
Schistosoma mansoni hypothetical protein 0.0282 0.1177 0.3071
Trypanosoma cruzi copper-transporting ATPase-like protein, putative 0.0026 0.0053 0.0094
Plasmodium vivax heterochromatin protein 1, putative 0.0034 0.0087 0.1422
Trypanosoma brucei trypanothione reductase 0.0153 0.0611 0.879
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.004 0.0115 0.1197
Trypanosoma brucei glucosidase, putative 0.0035 0.0094 0.1347
Giardia lamblia Phospholipid-transporting ATPase IA, putative 0.0026 0.0053 0.0267
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.0018 0.0018 0.0047
Loa Loa (eye worm) calcium/calmodulin-stimulated cyclic nucleotide phosphodiesterase 0.0057 0.0188 0.0945
Echinococcus multilocularis peroxidasin 0.0026 0.0052 0.0136
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0026 0.0054 0.0141
Mycobacterium tuberculosis Cation transporter P-type ATPase a CtpA 0.0026 0.0053 0.0074
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0468 0.1992 0.5197
Loa Loa (eye worm) hypothetical protein 0.0122 0.0473 0.2376
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0018 0.0018 0.009
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0018 0.0186
Trypanosoma cruzi DNA damage repair protein, putative 0.0036 0.0098 0.0173
Entamoeba histolytica cysteine protease, putative 0.004 0.0113 0.196
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0018 0.0018 0.0047
Schistosoma mansoni camp-specific cyclic nucleotide phosphodiesterase 0.0057 0.0188 0.0491
Trypanosoma brucei vacuolar-type Ca2+-ATPase 2 0.0093 0.0347 0.4989
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.0093 0.0347 0.3612
Loa Loa (eye worm) hypothetical protein 0.0026 0.0052 0.0261
Brugia malayi MH2 domain containing protein 0.0026 0.0054 0.031
Loa Loa (eye worm) hypothetical protein 0.0026 0.0052 0.0261
Trypanosoma brucei DNA polymerase IV, putative 0.0137 0.0538 0.7742
Trichomonas vaginalis cation-transporting ATPase, putative 0.0093 0.0347 0.3612
Trichomonas vaginalis set domain proteins, putative 0.0233 0.096 1
Echinococcus multilocularis chromobox protein 1 0.015 0.0596 0.1555
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0035 0.0092 0.1324
Toxoplasma gondii shikimate dehydrogenase substrate binding domain-containing protein 0.0647 0.2775 1
Brugia malayi Papain family cysteine protease containing protein 0.0056 0.0183 0.105
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0024 0.0044 0.0078
Loa Loa (eye worm) hypothetical protein 0.0034 0.0088 0.044
Schistosoma mansoni hypothetical protein 0.0023 0.0037 0.0097
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0018 0.0018 0.0293
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0036 0.0094 0.0245
Brugia malayi CHD4 protein 0.0036 0.0094 0.0539
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.005 0.0157 0.0279
Loa Loa (eye worm) helicase 0.0034 0.0087 0.0436
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0117 0.0452 0.2268
Plasmodium vivax vivapain-1 0.004 0.0113 0.1852
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0057 0.0188 0.1961
Schistosoma mansoni chromobox protein 0.0034 0.0087 0.0227
Trichomonas vaginalis conserved hypothetical protein 0.0037 0.0102 0.1062
Echinococcus granulosus plasma membrane calcium transporting ATPase 2 0.0093 0.0347 0.0904
Trypanosoma brucei cAMP-specific phosphodiesterase 0.0057 0.0188 0.2709
Leishmania major hypothetical protein, conserved 0.0057 0.0188 0.2709
Loa Loa (eye worm) hypothetical protein 0.0026 0.0052 0.0261
Echinococcus granulosus Chromobox protein 3 0.0034 0.0087 0.0227
Giardia lamblia CAMP-specific 3,5-cyclic phosphodiesterase 4B 0.0468 0.1992 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0056 0.0183 0.1906
Plasmodium vivax SET domain protein, putative 0.003 0.0069 0.1133
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0035 0.0094 0.1623
Echinococcus multilocularis calcium:calmodulin dependent 3',5' cyclic 0.0057 0.0188 0.0491
Echinococcus granulosus Alpha N acetylgalactosaminidase 0.01 0.0379 0.0988
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0148 0.0588 0.8458
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.012 0.1249
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0146 0.0577 0.1505
Schistosoma mansoni microtubule-associated protein tau 0.0677 0.2906 0.758
Loa Loa (eye worm) hypothetical protein 0.0051 0.0161 0.0807
Brugia malayi Cathepsin L-like precursor 0.0056 0.0183 0.105
Trypanosoma cruzi P-type H+-ATPase, putative 0.0053 0.017 0.0302
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0057 0.0188 0.0334
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0014 0.0001 0.0001
Trypanosoma cruzi cysteine peptidase, putative 0.0148 0.0588 0.1044
Mycobacterium tuberculosis Probable metal cation transporter ATPase P-type CtpE 0.0026 0.0053 0.0074
Echinococcus multilocularis phospholipid transporting ATPase VA 0.0017 0.0011 0.0028
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0018 0.0186
Schistosoma mansoni patched 1 0.0041 0.012 0.0313
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0044 0.0131 0.0343
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0057 0.0188 0.1961
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.0411 0.1742 0.4545
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0053 0.0171 0.2464
Leishmania major phosphopantetheinyl transferase-like protein 0.0023 0.0039 0.0557
Loa Loa (eye worm) CXXC zinc finger family protein 0.0028 0.0062 0.031
Entamoeba histolytica plasma membrane calcium-transporting ATPase 1, putative 0.0057 0.0188 0.3251
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0057 0.0188 0.1961
Plasmodium falciparum DNA repair protein REV1, putative 0.0036 0.0098 0.1598
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0057 0.0188 0.1961
Mycobacterium tuberculosis Putative ferredoxin reductase 0.035 0.1472 0.2055
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0057 0.0188 0.0678
Trichomonas vaginalis pc-MYB2, putative 0.006 0.0199 0.2075
Echinococcus multilocularis survival motor neuron protein 1 0.0232 0.0955 0.2491
Echinococcus granulosus calcium:calmodulin dependent 3'5' cyclic 0.0057 0.0188 0.0491
Plasmodium falciparum 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0057 0.0188 0.3081
Echinococcus granulosus Smad4 0.0026 0.0054 0.0141
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0057 0.0188 0.0678
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0003 0.0031
Toxoplasma gondii cation-transporting atpase family protein 0.0017 0.0011 0.0039
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.004 0.0113 0.1179
Trypanosoma brucei unspecified product 0.0137 0.0538 0.7742
Loa Loa (eye worm) hypothetical protein 0.0026 0.0052 0.0261
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.0057 0.0188 0.0491
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0018 0.0018 0.0047
Loa Loa (eye worm) intermediate filament protein 0.0026 0.0054 0.0272
Leishmania major copper-transporting ATPase-like protein, putative 0.0026 0.0053 0.0765
Schistosoma mansoni glutamate synthase 0.0014 0.0000033761 0.0000088073
Entamoeba histolytica calcium-transporting P-type ATPase, putative 0.0083 0.0302 0.5243
Mycobacterium leprae PROBABLE UDP-N-ACETYLGLUCOSAMINE 1-CARBOXYVINYLTRANSFERASE MURA 0.1647 0.7163 1
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0097 0.0362 0.6267
Echinococcus granulosus calcium transporting atpase 0.0101 0.0382 0.0998
Trichomonas vaginalis chromobox protein, putative 0.015 0.0596 0.6214
Trypanosoma brucei unspecified product 0.0081 0.0292 0.4209
Brugia malayi Peroxidasin 0.0026 0.0052 0.0298
Echinococcus multilocularis lysosomal alpha glucosidase 0.016 0.0639 0.1666
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0043 0.0443
Brugia malayi Sodium/potassium-transporting ATPase alpha-3 chain, putative 0.0036 0.0097 0.0558
Echinococcus granulosus calcium transporting ATPase type 2C member 0.0118 0.0455 0.1187
Toxoplasma gondii phospholipid-translocating P-type ATPase, flippase subfamily protein 0.0017 0.0011 0.0039
Plasmodium falciparum LCCL domain-containing protein 0.0019 0.0023 0.0375
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0022 0.0033 0.0168
Echinococcus granulosus phospholipid transporting ATPase IIB 0.0026 0.0053 0.0139
Trypanosoma brucei hypothetical protein, conserved 0.0057 0.0188 0.2709
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.004 0.0113 0.0295
Trichomonas vaginalis cGMP-inhibited 3,5-cyclic phosphodiesterase, putative 0.0057 0.0188 0.1961
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0023 0.0039 0.0039
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0021 0.003 0.0425
Onchocerca volvulus Cathepsin L homolog 0.0056 0.0183 0.1906
Brugia malayi ImpB/MucB/SamB family protein 0.0117 0.0452 0.2594
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0053 0.0171 0.2464
Schistosoma mansoni hypothetical protein 0.0888 0.3833 1
Brugia malayi Papain family cysteine protease containing protein 0.004 0.0113 0.0649
Trypanosoma brucei cAMP phosphodiesterase A, putative 0.0057 0.0188 0.2709
Plasmodium vivax vivapain-2 0.0056 0.0183 0.2995
Echinococcus granulosus chromobox protein 1 0.015 0.0596 0.1555
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0056 0.0183 0.1906
Giardia lamblia Cysteine protease 0.0018 0.0018 0.009
Plasmodium vivax serine-repeat antigen 4 (SERA), putative 0.0018 0.0018 0.0293
Loa Loa (eye worm) RNA binding protein 0.0068 0.0235 0.118
Brugia malayi hypothetical protein 0.005 0.0159 0.0913
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0014 0.0000033761 0.0000088073
Onchocerca volvulus 0.0082 0.0296 0.308
Echinococcus granulosus dna polymerase eta 0.0172 0.0695 0.1812
Schistosoma mansoni DNA polymerase IV / kappa 0.0036 0.0098 0.0255
Brugia malayi Melibiase family protein 0.0067 0.0232 0.1331
Brugia malayi Cathepsin L-like precursor 0.0056 0.0183 0.105
Trypanosoma cruzi DNA polymerase kappa, putative 0.0143 0.0566 0.1006
Onchocerca volvulus Huntingtin homolog 0.012 0.0465 0.4844
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0014 0.0000033761 0.0000088073
Entamoeba histolytica Plasma membrane calcium-transporting ATPase, putative 0.0093 0.0347 0.6009
Toxoplasma gondii cathepsin CPC2 0.0018 0.0018 0.0064
Schistosoma mansoni terminal deoxycytidyl transferase 0.0117 0.0452 0.1179
Brugia malayi CHE-14 protein 0.0041 0.012 0.0688
Plasmodium vivax copper-transporting ATPase, putative 0.0026 0.0053 0.087
Toxoplasma gondii plasma membrane-type Ca(2+)-ATPase A1 PMCAA1 0.0077 0.0274 0.0987
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0117 0.0452 0.1179
Brugia malayi Probable 3',5'-cyclic phosphodiesterase T04D3.3, putative 0.0057 0.0188 0.108
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0035 0.0094 0.1623
Echinococcus multilocularis sulfide:quinone oxidoreductase 0.0014 0.0000033761 0.0000088073
Brugia malayi Glycosyl hydrolases family 31 protein 0.016 0.0639 0.3666
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0057 0.0188 0.0678
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0018 0.0018 0.0047
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0057 0.0188 0.1961
Plasmodium vivax serine-repeat antigen 5 (SERA) 0.0018 0.0018 0.0293
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0019 0.002 0.0052
Entamoeba histolytica myb-like DNA-binding domain containing protein 0.006 0.0199 0.3452
Loa Loa (eye worm) hypothetical protein 0.0026 0.0053 0.0267
Brugia malayi hypothetical protein 0.0122 0.0474 0.272
Trypanosoma cruzi calcium-transporting ATPase, putative 0.004 0.0113 0.02
Leishmania major cathepsin L-like protease 0.0056 0.0183 0.2633
Giardia lamblia Hypothetical protein 0.0018 0.0018 0.009
Loa Loa (eye worm) hypothetical protein 0.0172 0.0695 0.3487
Giardia lamblia Plasma membrane calcium-transporting ATPase 2 0.0066 0.023 0.1153
Brugia malayi polk-prov protein 0.0062 0.0212 0.1217
Trypanosoma brucei protein kinase, putative 0.005 0.0157 0.2264
Entamoeba histolytica cysteine proteinase, putative 0.0056 0.0183 0.3171
Brugia malayi Thioredoxin reductase 0.0153 0.0611 0.3505
Echinococcus multilocularis Niemann Pick C1 protein 0.0097 0.0362 0.0943
Echinococcus granulosus dnaJ subfamily B 0.0401 0.1697 0.4427
Brugia malayi Protein cec-1. 0.0034 0.0087 0.0499
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0003 0.0031
Schistosoma mansoni atpase class VI type 11c 0.0017 0.0011 0.0028
Brugia malayi hypothetical protein 0.0019 0.0023 0.0132
Brugia malayi Calcitonin receptor-like protein seb-1 0.0053 0.0172 0.0986
Mycobacterium tuberculosis Probable metal cation transporter P-type ATPase CtpV 0.0026 0.0053 0.0074
Giardia lamblia Cathepsin L precursor 0.0018 0.0018 0.009
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0018 0.0018 0.0047
Treponema pallidum cation-transporting ATPase, P-type 0.0026 0.0053 0.0053
Schistosoma mansoni cation-transporting atpase worm 0.0026 0.0053 0.0139
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0053 0.0172 0.0863
Leishmania major phosphatidylinositol 3-kinase, putative 0.0015 0.0003 0.0042
Echinococcus granulosus lipoxygenase domain containing protein 0.0019 0.0023 0.006
Echinococcus multilocularis cathepsin b 0.0018 0.0018 0.0047
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.0018 0.0018 0.0293
Echinococcus granulosus mitogen activated protein kinase 3 0.005 0.0157 0.041
Trichomonas vaginalis conserved hypothetical protein 0.0089 0.0329 0.3424
Entamoeba histolytica cysteine protease, putative 0.004 0.0113 0.196
Giardia lamblia DINP protein human, muc B family 0.0124 0.048 0.241
Echinococcus granulosus Polycystic kidney disease protein 0.0019 0.0023 0.006
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0053 0.0171 0.2464
Trichomonas vaginalis conserved hypothetical protein 0.0055 0.018 0.1874
Echinococcus granulosus Chromo domain 0.0034 0.0087 0.0227
Giardia lamblia DNA damage repair protein 0.0036 0.0098 0.049
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0018 0.0018 0.0047
Leishmania major cAMP phosphodiesterase A, putative;with=GeneDB:LinJ18_V3.1100 0.0057 0.0188 0.2709
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.003 0.0069 0.0249
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.005 0.0157 0.0279
Brugia malayi hypothetical protein 0.0026 0.0052 0.0298
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0034 0.0087 0.0227
Echinococcus multilocularis high affinity cgmp specific 3' 5' cyclic 0.0057 0.0188 0.0491
Trypanosoma brucei DNA polymerase kappa, putative 0.0143 0.0566 0.815
Giardia lamblia Copper-transporting P-type ATPase 0.0026 0.0053 0.0267
Leishmania major P-type H -ATPase, putative 0.0053 0.017 0.2446
Giardia lamblia Hypothetical protein 0.0018 0.0018 0.009
Loa Loa (eye worm) animal heme peroxidase 0.0026 0.0052 0.0261
Brugia malayi ImpB/MucB/SamB family protein 0.0172 0.0695 0.3988
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0023 0.0039 0.0139
Mycobacterium tuberculosis Probable dehydrogenase 0.035 0.1472 0.2055
Trypanosoma brucei DNA polymerase kappa, putative 0.0087 0.0321 0.4617
Loa Loa (eye worm) glutathione reductase 0.0153 0.0611 0.3065
Brugia malayi hypothetical protein 0.0119 0.0462 0.265
Giardia lamblia Cysteine protease 0.0018 0.0018 0.009
Giardia lamblia Cathepsin B-like cysteine proteinase 3 precursor 0.0018 0.0018 0.009
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.0018 0.0018 0.0293
Loa Loa (eye worm) hypothetical protein 0.0034 0.0088 0.044
Onchocerca volvulus 0.0056 0.0183 0.1906
Trypanosoma cruzi DNA damage repair protein, putative 0.0036 0.0098 0.0173
Brugia malayi Animal haem peroxidase family protein 0.0026 0.0052 0.0298
Schistosoma mansoni copper ABC transporter ATPase 0.0026 0.0053 0.0139
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0092 0.0957
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.005 0.0157 0.079
Echinococcus granulosus cathepsin L 0.0018 0.0018 0.0047
Giardia lamblia Cathepsin L precursor 0.0018 0.0018 0.009
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0018 0.0186
Onchocerca volvulus 0.0083 0.0302 0.3151
Trichomonas vaginalis r2r3-MYB transcription factor, putative 0.006 0.0199 0.2075
Loa Loa (eye worm) RecQ helicase 0.0045 0.0137 0.0685
Echinococcus granulosus Na:K ATPase alpha subunit 0.0066 0.023 0.0599
Brugia malayi calcium ATPase 0.0036 0.0097 0.0558
Trypanosoma cruzi DNA polymerase eta, putative 0.0092 0.034 0.0605
Mycobacterium ulcerans cation transporter p-type ATPase a CtpA 0.0026 0.0053 0.0053
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0034 0.0087 0.0227
Brugia malayi hypothetical protein 0.0019 0.0023 0.0132
Mycobacterium ulcerans 3-phosphoshikimate 1-carboxyvinyltransferase 0.0647 0.2775 0.2775
Leishmania major calcium-transporting ATPase, putative 0.0066 0.023 0.3306
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0047 0.0146 0.0836
Schistosoma mansoni ATPase 0.0118 0.0455 0.1187
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0018 0.0186
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0034 0.0087 0.0905
Echinococcus multilocularis lamin dm0 0.0026 0.0054 0.0141
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0043 0.0443
Toxoplasma gondii histone lysine methyltransferase SET1 0.0054 0.0177 0.0637
Leishmania major calcium motive p-type ATPase, putative 0.0066 0.023 0.3306
Schistosoma mansoni ATPase 0.0118 0.0455 0.1187
Schistosoma mansoni cathepsin F (C01 family) 0.0056 0.0183 0.0477
Echinococcus multilocularis protein dispatched 1 0.0047 0.0146 0.038
Entamoeba histolytica cysteine proteinase 1, putative 0.004 0.0113 0.196
Brugia malayi Papain family cysteine protease containing protein 0.004 0.0113 0.0649
Trypanosoma cruzi DNA polymerase eta, putative 0.0172 0.0695 0.1234
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.004 0.0113 0.0201
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0056 0.0183 0.1906
Mycobacterium ulcerans cation-transporter p-type ATPase B CtpB 0.0026 0.0053 0.0053
Trichomonas vaginalis conserved hypothetical protein 0.0089 0.0329 0.3424
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0056 0.0183 0.1906
Toxoplasma gondii preprocathepsin c precursor, putative 0.0018 0.0018 0.0064
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0018 0.0186
Brugia malayi CXXC zinc finger family protein 0.0028 0.0062 0.0354
Schistosoma mansoni cation-transporting atpase 13a1 (G-box binding protein) 0.0026 0.0053 0.0139
Echinococcus granulosus RUN 0.0019 0.0023 0.006
Mycobacterium ulcerans metal cation-transporting p-type ATPase F, CtpF 0.0118 0.0455 0.0455
Giardia lamblia Sgs1 DNA helicase, putative 0.0019 0.002 0.0101
Mycobacterium tuberculosis Possible metal cation transporting P-type ATPase CtpH 0.0056 0.0186 0.0259
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0057 0.0188 0.0678
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0023 0.0039 0.0039
Trichomonas vaginalis chromobox protein, putative 0.0095 0.0355 0.3694
Trichomonas vaginalis r2r3-MYB transcription factor, putative 0.006 0.0199 0.2075
Onchocerca volvulus 0.0048 0.0151 0.1571
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0018 0.0018 0.0047
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0019 0.002 0.0072
Loa Loa (eye worm) hypothetical protein 0.0067 0.0232 0.1164
Giardia lamblia Cysteine protease 0.0018 0.0018 0.009
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0017 0.0012 0.0032
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0234 0.0965 0.4843
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0064 0.0663
Brugia malayi Calcium-transporting ATPase sarcoplasmic/endoplasmic reticulum type 0.0101 0.0382 0.2195
Onchocerca volvulus 0.0026 0.0052 0.0541
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0082 0.0853
Schistosoma mansoni hypothetical protein 0.0146 0.0577 0.1505
Toxoplasma gondii Alpha-galactosidase 0.0014 0.0001 0.0002
Loa Loa (eye worm) hypothetical protein 0.0083 0.0302 0.1518
Schistosoma mansoni hypothetical protein 0.0036 0.0098 0.0255
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.0093 0.0347 0.3612
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.01 0.0379 0.0988
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0023 0.0037 0.0097
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0053 0.0171 0.2803
Brugia malayi RNA recognition motif domain containing protein 0.0068 0.0235 0.135
Plasmodium vivax 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0057 0.0188 0.3081
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0057 0.0188 0.1961
Echinococcus granulosus dual 3'5' cyclic AMP and GMP phosphodiesterase 0.0057 0.0188 0.0491
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0035 0.0092 0.1324
Giardia lamblia Hypothetical protein 0.0057 0.0188 0.0944
Echinococcus multilocularis neutral alpha glucosidase AB 0.0035 0.0094 0.0244
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0057 0.0188 0.1961
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0056 0.0183 0.1906
Plasmodium falciparum serine repeat antigen 3 0.0018 0.0018 0.0293
Plasmodium vivax hypothetical protein, conserved 0.0034 0.0087 0.1422
Mycobacterium leprae probable 3-phosphoshikimate 1-carboxyvinyl transferase AroA (5-ENOLPYRUVYLSHIKIMATE-3-PHOSPHATE SYNTHASE) (EPSP SYNTHASE) (EPSPS 0.0647 0.2775 0.3873
Plasmodium vivax serine-repeat antigen 2 (SERA) 0.0018 0.0018 0.0293
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0057 0.0188 0.0678
Loa Loa (eye worm) hypothetical protein 0.0026 0.0052 0.0261
Wolbachia endosymbiont of Brugia malayi UDP-N-acetylglucosamine 1-carboxyvinyltransferase 0.2294 1 1
Trypanosoma cruzi major cysteine proteinase, putative 0.0018 0.0018 0.0032
Giardia lamblia Cathepsin L-like protease 0.0018 0.0018 0.009
Brugia malayi hypothetical protein 0.0232 0.0955 0.5482
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.005 0.0157 0.0279
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0037 0.0102 0.1062
Echinococcus granulosus intermediate filament protein 0.0026 0.0054 0.0141
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.005 0.0157 0.2264
Loa Loa (eye worm) hypothetical protein 0.0089 0.0329 0.1649
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.0018 0.0018 0.0257
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0146 0.0577 0.1505
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0018 0.0018 0.0186
Plasmodium falciparum serine repeat antigen 4 0.0018 0.0018 0.0293
Schistosoma mansoni smad1 5 8 and 0.0026 0.0054 0.0141
Leishmania major P-type H -ATPase, putative 0.0053 0.017 0.2446
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0389 0.1643 0.2294
Trichomonas vaginalis chromobox protein, putative 0.0034 0.0087 0.0905
Trichomonas vaginalis Clan CA, family C1, cathepsin H-like cysteine peptidase 0.0018 0.0018 0.0186
Trichomonas vaginalis PIKK family atypical protein kinase 0.0044 0.0131 0.1369
Echinococcus multilocularis sarco:endoplasmic reticulum calcium ATPase 0.0118 0.0455 0.1187
Brugia malayi follicle stimulating hormone receptor 0.0234 0.0965 0.5538
Leishmania major DNA polymerase eta, putative 0.0092 0.034 0.4901
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0054 0.0176 0.0458
Echinococcus multilocularis tumor protein p63 0.0331 0.1391 0.3629
Echinococcus granulosus thioredoxin glutathione reductase 0.0153 0.0611 0.1593
Trichomonas vaginalis C-MYB, putative 0.006 0.0199 0.2075
Giardia lamblia Cathepsin L-like protease 0.0018 0.0018 0.009
Echinococcus multilocularis apoptosis inducing factor 1 mitochondrial 0.0014 0.0000033761 0.0000088073
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0035 0.0094 0.0976
Plasmodium falciparum serine repeat antigen 5 0.0018 0.0018 0.0293
Schistosoma mansoni alpha-glucosidase 0.0137 0.0541 0.1412
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.0468 0.1992 0.5197
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0057 0.0188 0.1961
Trichomonas vaginalis chromobox protein, putative 0.0034 0.0087 0.0905
Entamoeba histolytica hypothetical protein 0.0034 0.0087 0.1506
Loa Loa (eye worm) hypothetical protein 0.0097 0.0362 0.1815
Brugia malayi potential phospholipid-transporting ATPase IIB, putative 0.0026 0.0053 0.0305
Echinococcus granulosus X box binding protein 1 0.0282 0.1177 0.3071
Trypanosoma cruzi calcium motive p-type ATPase, putative 0.0066 0.023 0.0408
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0044 0.0131 0.0233
Schistosoma mansoni lamin 0.0026 0.0054 0.0141
Brugia malayi hypothetical protein 0.0146 0.0577 0.3311
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.0057 0.0188 0.0491
Plasmodium falciparum non-SERCA-type Ca2+ -transporting P-ATPase 0.0118 0.0455 0.7454
Plasmodium falciparum thioredoxin reductase 0.0053 0.0171 0.2803
Loa Loa (eye worm) hypothetical protein 0.0026 0.0052 0.0261
Schistosoma mansoni hypothetical protein 0.004 0.0113 0.0296
Trypanosoma cruzi trypanothione reductase, putative 0.0153 0.0611 0.1085
Brugia malayi chromobox protein homolog 3 0.0089 0.0329 0.1886
Entamoeba histolytica hypothetical protein 0.0018 0.0018 0.031
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0056 0.0183 0.1906
Trypanosoma brucei DNA polymerase IV, putative 0.0143 0.0566 0.815
Leishmania major P-type ATPase, putative 0.0077 0.0274 0.3942
Trichomonas vaginalis MYB, putative 0.006 0.02 0.2088
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.0043 0.0126 0.0454
Echinococcus multilocularis lysosomal alpha glucosidase 0.016 0.0639 0.1666
Toxoplasma gondii Myb family DNA-binding domain-containing protein 0.006 0.02 0.0722
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0057 0.0188 0.1961
Echinococcus multilocularis mitogen activated protein kinase 0.005 0.0157 0.041
Loa Loa (eye worm) cytochrome P450 family protein 0.0026 0.0051 0.0254
Loa Loa (eye worm) hypothetical protein 0.003 0.0071 0.0355
Trypanosoma brucei DNA polymerase kappa, putative 0.0143 0.0566 0.815
Trichomonas vaginalis hypothetical protein 0.0034 0.0087 0.0905
Brugia malayi Cytochrome P450 family protein 0.0016 0.0006 0.0036
Entamoeba histolytica myb-like DNA-binding domain containing protein 0.006 0.0199 0.3452
Trichomonas vaginalis cation-transporting ATPase, putative 0.0118 0.0455 0.4744
Echinococcus multilocularis dual 3',5' cyclic AMP and GMP phosphodiesterase 0.0057 0.0188 0.0491
Trypanosoma brucei DNA polymerase kappa, putative 0.0124 0.048 0.6912
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0017 0.0012 0.0032
Trypanosoma cruzi PAB1-binding protein , putative 0.005 0.0159 0.0282
Onchocerca volvulus Dual oxidase homolog 0.0026 0.0052 0.0541
Trypanosoma cruzi cruzipain precursor, putative 0.1298 0.5631 1
Trypanosoma cruzi copper-transporting ATPase-like protein, putative 0.0026 0.0053 0.0094
Trypanosoma cruzi hypothetical protein, conserved 0.0057 0.0188 0.0334
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0148 0.0588 0.8458
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0057 0.0188 0.1961
Loa Loa (eye worm) hypothetical protein 0.0026 0.0052 0.0261
Trichomonas vaginalis ATPase, class VI, type 11C, putative 0.0026 0.0053 0.0554
Giardia lamblia Plasma membrane calcium-transporting ATPase 2 0.0093 0.0347 0.174
Echinococcus multilocularis cpg binding protein 0.003 0.0069 0.0179
Schistosoma mansoni sulfide quinone reductase 0.0014 0.0000033761 0.0000088073
Plasmodium vivax cation transporting ATPase, putative 0.0026 0.0053 0.087
Treponema pallidum UDP-N-acetylglucosamine 1-carboxyvinyltransferase 0.2294 1 1
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0018 0.0018 0.0047
Trichomonas vaginalis r2r3-MYB transcription factor, putative 0.006 0.02 0.2088
Loa Loa (eye worm) Na,K-ATPase alpha subunit 0.0083 0.0302 0.1518
Trypanosoma cruzi cytochrome P450, putative 0.0016 0.0006 0.0011
Trichomonas vaginalis chromobox protein, putative 0.0034 0.0087 0.0905
Brugia malayi Animal haem peroxidase family protein 0.0026 0.0052 0.0298
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.0087 0.0905
Trypanosoma cruzi target of rapamycin kinase 3 0.0035 0.0092 0.0163
Echinococcus multilocularis calcium:calmodulin dependent 3',5' cyclic 0.0057 0.0188 0.0491
Trypanosoma cruzi DNA polymerase kappa, putative 0.0143 0.0566 0.1006
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.004 0.0113 0.1628
Treponema pallidum 4'-phosphopantetheinyl transferase 0.0023 0.0039 0.0039
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0015 0.0003 0.0008
Schistosoma mansoni lipoxygenase 0.0054 0.0176 0.0458
Giardia lamblia Cathepsin B precursor 0.0018 0.0018 0.009
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0053 0.0171 0.0304
Giardia lamblia Cysteine protease 0.0018 0.0018 0.009
Echinococcus multilocularis chromobox protein 2 0.0034 0.0087 0.0227
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0057 0.0188 0.1961
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.01 0.0379 0.0988
Loa Loa (eye worm) hypothetical protein 0.0026 0.0053 0.0267
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0153 0.0611 0.0852
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.0094 0.0976
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.0087 0.0905
Trypanosoma cruzi cysteine peptidase, putative 0.0056 0.0183 0.0325
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.0014 0.000000016131 0.00000004208
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0054 0.0559
Echinococcus granulosus cathepsin b 0.0018 0.0018 0.0047
Entamoeba histolytica cysteine protease, putative 0.004 0.0113 0.196
Schistosoma mansoni cathepsin C 0.0018 0.0018 0.0047
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0019 0.002 0.0115
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0044 0.0131 0.1891
Echinococcus multilocularis phospholipid transporting ATPase IIB 0.0026 0.0053 0.0139
Entamoeba histolytica cysteine protease, putative 0.004 0.0113 0.196
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.004 0.0115 0.1197
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0053 0.0171 0.2803
Plasmodium falciparum dipeptidyl aminopeptidase 1 0.0018 0.0018 0.0293
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0018 0.0018 0.0047
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0014 0.0001 0.0001
Trichomonas vaginalis cation-transporting ATPase fungi, putative 0.0093 0.0347 0.3612
Giardia lamblia Kinase, CMGC MAPK 0.005 0.0157 0.0789
Brugia malayi TAR-binding protein 0.0068 0.0235 0.135
Brugia malayi SET domain containing protein 0.0036 0.0094 0.0541
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0094 0.0166
Echinococcus multilocularis mothers against decapentaplegic 5 0.0026 0.0054 0.0141
Trichomonas vaginalis Clan CA, family C1, cathepsin L or H-like cysteine peptidase 0.0018 0.0018 0.0186
Trichomonas vaginalis cGMP-inhibited 3,5-cyclic phosphodiesterase, putative 0.0057 0.0188 0.1961
Echinococcus granulosus expressed conserved protein 0.0091 0.0336 0.0876
Echinococcus multilocularis cation transporting ATPase 13A3 0.0026 0.0053 0.0139
Trypanosoma cruzi copper-transporting ATPase, putative 0.0017 0.0011 0.0019
Trichomonas vaginalis DNA polymerase eta, putative 0.0143 0.0566 0.5901
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0057 0.0188 0.0678
Entamoeba histolytica myb-like DNA-binding domain containing protein 0.006 0.0199 0.3452
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.003 0.0071 0.0255
Brugia malayi MH2 domain containing protein 0.0388 0.1639 0.9407
Brugia malayi Probable 3',5'-cyclic phosphodiesterase R153.1, putative 0.0057 0.0188 0.108
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.004 0.0115 0.1197
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0092 0.0957
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0054 0.0559
Onchocerca volvulus 0.0018 0.0018 0.0186
Giardia lamblia NADH oxidase lateral transfer candidate 0.0053 0.0171 0.0859
Trypanosoma cruzi cAMP phosphodiesterase A, putative 0.0057 0.0188 0.0334
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0003 0.0031
Trypanosoma cruzi cAMP-specific phosphodiesterase, putative 0.0057 0.0188 0.0334
Brugia malayi Papain family cysteine protease containing protein 0.0018 0.0018 0.0103
Schistosoma mansoni DNA polymerase eta 0.0172 0.0695 0.1812
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0053 0.0171 0.0304
Leishmania major hypothetical protein, conserved 0.005 0.0159 0.229
Brugia malayi Animal haem peroxidase family protein 0.0026 0.0052 0.0298
Schistosoma mansoni chromobox protein 0.0034 0.0087 0.0227
Trypanosoma brucei calcium-translocating P-type ATPase 0.0101 0.0382 0.5505
Trichomonas vaginalis r2r3-MYB transcription factor, putative 0.006 0.0199 0.2075
Echinococcus granulosus neuropeptide receptor A26 0.046 0.1954 0.5097
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0053 0.0171 0.0617
Loa Loa (eye worm) hypothetical protein 0.0026 0.0052 0.0261
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0018 0.0186
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0018 0.0018 0.009
Trichomonas vaginalis CMGC family protein kinase 0.005 0.0157 0.1639
Schistosoma mansoni lipoxygenase 0.0019 0.0023 0.006
Loa Loa (eye worm) hypothetical protein 0.0018 0.0018 0.009
Echinococcus granulosus high affinity cAMP specific 3'5' cyclic 0.0057 0.0188 0.0491
Trichomonas vaginalis PIKK family atypical protein kinase 0.0044 0.0131 0.1369
Brugia malayi Niemann-Pick C1 protein precursor 0.0097 0.0362 0.2075
Chlamydia trachomatis holo [acyl-carrier protein] synthase 0.0023 0.0039 0.0039
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.004 0.0115 0.1197
Loa Loa (eye worm) hypothetical protein 0.0018 0.0018 0.009
Trichomonas vaginalis cation-transporting ATPase, putative 0.0026 0.0053 0.0554
Echinococcus multilocularis cathepsin L 0.004 0.0113 0.0295
Echinococcus multilocularis cysteine protease 0.0056 0.0183 0.0477
Mycobacterium tuberculosis Probable reductase 0.035 0.1472 0.2055
Giardia lamblia Cathepsin B precursor 0.0018 0.0018 0.009
Mycobacterium ulcerans hypothetical protein 0.0036 0.0098 0.0098
Plasmodium falciparum glutathione reductase 0.0053 0.0171 0.2803
Echinococcus multilocularis Ankyrin repeat domain containing protein 0.0088 0.0325 0.0847
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0056 0.0183 0.1906
Toxoplasma gondii target of rapamycin (TOR), putative 0.0033 0.0082 0.0295
Echinococcus multilocularis Chromobox protein 3 0.0034 0.0087 0.0227
Treponema pallidum NADH oxidase 0.0053 0.0171 0.0171
Brugia malayi Cathepsin L-like precursor 0.0056 0.0183 0.105
Echinococcus multilocularis cathepsin b 0.0018 0.0018 0.0047
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0057 0.0188 0.1961
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0056 0.0183 0.1906
Echinococcus granulosus cathepsin l1 0.0056 0.0183 0.0477
Loa Loa (eye worm) calcium ATPase 0.002 0.0025 0.0123
Brugia malayi Papain family cysteine protease containing protein 0.0018 0.0018 0.0103
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.005 0.0157 0.0567
Echinococcus granulosus NADPH:adrenodoxin oxidoreductase 0.0014 0.0000033761 0.0000088073
Schistosoma mansoni DNA helicase recq1 0.0019 0.002 0.0052
Loa Loa (eye worm) hypothetical protein 0.0048 0.0151 0.0757
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0389 0.1643 0.2294
Trypanosoma cruzi copper-transporting ATPase-like protein, putative 0.0017 0.0011 0.0019
Loa Loa (eye worm) hypothetical protein 0.0018 0.0018 0.009
Trypanosoma brucei DNA polymerase kappa, putative 0.0143 0.0566 0.815
Trypanosoma brucei DNA polymerase kappa, putative 0.0143 0.0566 0.815
Loa Loa (eye worm) cytochrome P450 family protein 0.0016 0.0006 0.0032
Loa Loa (eye worm) hypothetical protein 0.0118 0.0455 0.2285
Echinococcus granulosus sterol regulatory element binding protein 0.0041 0.012 0.0313
Loa Loa (eye worm) hypothetical protein 0.0057 0.0188 0.0945
Brugia malayi Associated with TFs and helicases family protein 0.0034 0.0087 0.0499
Schistosoma mansoni rab6-interacting 0.0019 0.0023 0.006
Plasmodium vivax 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0057 0.0188 0.3081
Brugia malayi Bloom's syndrome protein homolog 0.0045 0.0137 0.0784
Toxoplasma gondii haloacid dehalogenase family hydrolase domain-containing protein 0.0017 0.0011 0.0039
Treponema pallidum hypothetical protein 0.0017 0.0011 0.0011
Entamoeba histolytica myb-like DNA-binding domain containing protein 0.006 0.0199 0.3452
Loa Loa (eye worm) TAR-binding protein 0.0068 0.0235 0.118
Entamoeba histolytica cysteine protease, putative 0.004 0.0113 0.196
Echinococcus granulosus cathepsin L cysteine proteinase 0.0056 0.0183 0.0477
Schistosoma mansoni calcium-transporting atpase sarcoplasmic/endoplasmic reticulum type (calcium pump) 0.0101 0.0382 0.0998
Loa Loa (eye worm) hypothetical protein 0.0026 0.0054 0.0272
Echinococcus multilocularis glutamate synthase 0.0014 0.0000033761 0.0000088073
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0053 0.0171 0.0447
Trypanosoma cruzi cysteine proteinase, putative 0.004 0.0113 0.0201
Entamoeba histolytica phospholipid-transporting P-type ATPase, putative 0.0026 0.0053 0.0921
Giardia lamblia Cathepsin L precursor 0.0018 0.0018 0.009
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0044 0.0131 0.2278
Trichomonas vaginalis cation-transporting ATPase, putative 0.0053 0.017 0.1771
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0057 0.0188 0.1961
Plasmodium falciparum 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0057 0.0188 0.3081
Trypanosoma brucei calcium-transporting ATPase, putative 0.004 0.0113 0.1624
Mycobacterium ulcerans cation transporter p-type ATPase D CtpD 0.0026 0.0053 0.0053
Loa Loa (eye worm) cysteine protease 0.0056 0.0183 0.0918
Onchocerca volvulus Huntingtin homolog 0.012 0.0465 0.4844
Trypanosoma brucei cysteine peptidase C (CPC) 0.0018 0.0018 0.0257
Loa Loa (eye worm) hypothetical protein 0.0041 0.012 0.0602
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0053 0.0171 0.2464
Plasmodium vivax phosphodiesterase gamma, putative 0.0057 0.0188 0.3081
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0022 0.0033 0.0192
Plasmodium falciparum ataxin-2 like protein, putative 0.005 0.0159 0.2605
Trypanosoma brucei cation-transporting ATPase, putative 0.0026 0.0053 0.0765
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0003 0.0031
Echinococcus multilocularis Glycoside hydrolase, family 27 0.01 0.0379 0.0988
Trypanosoma brucei DNA polymerase kappa, putative 0.0087 0.0321 0.4617
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0018 0.0018 0.009
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.0018 0.0018 0.009
Leishmania major DNA polymerase kappa, putative 0.0036 0.0098 0.1405
Onchocerca volvulus Chorion peroxidase homolog 0.0026 0.0052 0.0541
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0039 0.0109 0.0628
Toxoplasma gondii calcium-translocating P-type ATPase, PMCA-type protein 0.0093 0.0347 0.1249
Brugia malayi Probable cation-transporting ATPase C10C6.6 in chromosome IV 0.0026 0.0053 0.0305
Plasmodium vivax vivapain-3 0.004 0.0113 0.1852
Brugia malayi Glycosyl hydrolases family 31 protein 0.0035 0.0094 0.0537
Brugia malayi Cathepsin L-like precursor 0.0056 0.0183 0.105
Giardia lamblia Cathepsin L precursor 0.0018 0.0018 0.009
Trichomonas vaginalis conserved hypothetical protein 0.0057 0.0188 0.1961
Mycobacterium tuberculosis Probable metal cation transporter P-type ATPase A CtpF 0.0035 0.0091 0.0127
Toxoplasma gondii cathepsin CPL 0.0056 0.0183 0.0659
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.035 0.1472 0.2055
Schistosoma mansoni calcium-transporting atpase sarcoplasmic/endoplasmic reticulum type (calcium pump) 0.0101 0.0382 0.0998
Echinococcus multilocularis musashi 0.0026 0.0054 0.0141
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.0093 0.0347 0.3612
Plasmodium vivax vivapain-2 0.0056 0.0183 0.2995
Loa Loa (eye worm) sodium potassium adenosine triphosphatase 0.0036 0.0097 0.0488
Trichomonas vaginalis DNA helicase recq, putative 0.0024 0.0044 0.046
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0053 0.0171 0.0171
Onchocerca volvulus 0.0028 0.0062 0.0642
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0205 0.0836 0.4195
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0082 0.0853
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0057 0.0188 0.1961
Brugia malayi cathepsin L-like cysteine proteinase 0.0018 0.0018 0.0103
Schistosoma mansoni smad1 5 8 and 0.0026 0.0054 0.0141
Leishmania major calcium-translocating P-type ATPase 0.0118 0.0455 0.6552
Schistosoma mansoni cathepsin S (C01 family) 0.0018 0.0018 0.0047
Plasmodium falciparum phosphodiesterase gamma, putative 0.0057 0.0188 0.3081
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0057 0.0188 0.1961
Trichomonas vaginalis pc-MYB2, putative 0.006 0.0199 0.2075
Trypanosoma cruzi cAMP phosphodiesterase A, putative 0.0057 0.0188 0.0334
Echinococcus multilocularis lamin 0.0026 0.0054 0.0141
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0057 0.0188 0.1961
Plasmodium vivax unspecified product 0.004 0.0113 0.1852
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0037 0.01 0.104
Entamoeba histolytica cation-transporting P-typeATPase, putative 0.0026 0.0053 0.0921
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0018 0.0186
Plasmodium vivax hypothetical protein, conserved 0.0034 0.0087 0.1422
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.0093 0.0347 0.3612
Plasmodium vivax serine-repeat antigen (SERA) 0.0018 0.0018 0.0293
Entamoeba histolytica phospholipid-transporting P-type ATPase, putative 0.0026 0.0053 0.0921
Toxoplasma gondii thioredoxin reductase 0.0153 0.0611 0.2201
Brugia malayi Cytochrome P450 family protein 0.0016 0.0006 0.0036
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0017 0.0012 0.0032
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0072 0.0255 0.0665
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0057 0.0188 0.0491
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0057 0.0188 0.1961
Schistosoma mansoni hypothetical protein 0.004 0.0113 0.0296
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.0018 0.0018 0.0293
Plasmodium vivax cyclic nucleotide phosphodiesterase, putative 0.0057 0.0188 0.3081
Schistosoma mansoni plasma membrane calcium-transporting atpase 0.0077 0.0274 0.0714
Onchocerca volvulus 0.0064 0.0218 0.227
Loa Loa (eye worm) hypothetical protein 0.0061 0.0206 0.1033
Echinococcus granulosus neuropeptide s receptor 0.046 0.1954 0.5097
Loa Loa (eye worm) hypothetical protein 0.0015 0.0002 0.0011
Echinococcus multilocularis GPCR, family 2 0.0017 0.0012 0.0032
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0053 0.0171 0.2464
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0124 0.048 0.6912
Trichomonas vaginalis cAMP and cAMP-inhibited cGMP 3,5-cyclic phosphodiesterase, putative 0.0057 0.0188 0.1961
Echinococcus granulosus survival motor neuron protein 1 0.0232 0.0955 0.2491
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0023 0.0039 0.0139
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0053 0.0171 0.0304
Trichomonas vaginalis conserved hypothetical protein 0.0055 0.018 0.1874
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0018 0.0186
Entamoeba histolytica cysteine protease, putative 0.0018 0.0018 0.031
Entamoeba histolytica cysteine protease, putative 0.0018 0.0018 0.031
Loa Loa (eye worm) hypothetical protein 0.0053 0.0172 0.0863
Brugia malayi Cytochrome P450 family protein 0.0026 0.0051 0.0291
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0057 0.0188 0.1961
Onchocerca volvulus 0.0056 0.0183 0.1906
Echinococcus multilocularis Na+:K+ ATPase alpha subunit 0.0066 0.023 0.0599
Leishmania major DNA polymerase kappa, putative 0.0124 0.048 0.6912
Schistosoma mansoni polycystin 1-related 0.0019 0.0023 0.006
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0057 0.0188 0.1961
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0044 0.0131 0.0233
Trichomonas vaginalis chromobox protein, putative 0.0095 0.0355 0.3694
Onchocerca volvulus 0.0061 0.0206 0.2144
Trypanosoma cruzi cysteine peptidase, putative 0.1298 0.5631 1
Schistosoma mansoni Na+/K+ transporting ATPase subunit alpha 0.0083 0.0302 0.0789
Schistosoma mansoni plasma membrane calcium-transporting atpase 0.0077 0.0274 0.0714
Onchocerca volvulus 0.0047 0.0146 0.1517
Schistosoma mansoni multiple ankyrin repeats single kh domain protein 0.0088 0.0325 0.0847
Echinococcus multilocularis phosphoserine phosphatase 0.0017 0.0011 0.0028
Entamoeba histolytica cysteine protease, putative 0.0018 0.0018 0.031
Leishmania major cathepsin L-like protease 0.0056 0.0183 0.2633
Loa Loa (eye worm) hypothetical protein 0.0139 0.0548 0.275
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0057 0.0188 0.1961
Schistosoma mansoni hypothetical protein 0.004 0.0113 0.0296
Trypanosoma cruzi P-type H+-ATPase, putative 0.0036 0.0097 0.0173
Echinococcus granulosus cation transporting ATPase 13A1 0.0026 0.0053 0.0139
Schistosoma mansoni alpha glucosidase 0.0035 0.0094 0.0244
Brugia malayi Cathepsin L-like precursor 0.0034 0.0088 0.0504
Brugia malayi cahepsin L-like non-peptiedase homolog 0.0018 0.0018 0.0103
Schistosoma mansoni sulfide quinone reductase 0.0014 0.0000033761 0.0000088073
Loa Loa (eye worm) hypothetical protein 0.0026 0.0052 0.0261
Echinococcus multilocularis phosphoserine phosphatase 0.0017 0.0011 0.0028
Schistosoma mansoni hypothetical protein 0.0014 0.0000033761 0.0000088073
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.035 0.1472 0.2055
Echinococcus multilocularis protein patched 0.0041 0.012 0.0313
Echinococcus multilocularis Tetracycline resistance leader peptide, TetL 0.0093 0.0347 0.0904
Trichomonas vaginalis chromobox protein, putative 0.015 0.0596 0.6214
Leishmania major cathepsin L-like protease 0.0056 0.0183 0.2633
Echinococcus multilocularis dnaJ subfamily B 0.0401 0.1697 0.4427
Echinococcus multilocularis L aminoadipate semialdehyde 0.0082 0.0296 0.0771
Brugia malayi Cathepsin L-like precursor 0.0022 0.0033 0.0192
Mycobacterium ulcerans UDP-N-acetylglucosamine 1-carboxyvinyltransferase 0.2294 1 1
Schistosoma mansoni hypothetical protein 0.0047 0.0146 0.038
Mycobacterium tuberculosis Probable cation transporter P-type ATPase D CtpD 0.0026 0.0053 0.0074
Mycobacterium leprae Probable metal cation-transporting P-type ATPase C CtpC 0.0026 0.0053 0.0074
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0057 0.0188 0.1961
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0041 0.012 0.0602
Brugia malayi MAP kinase sur-1 0.005 0.0157 0.0903
Onchocerca volvulus 0.0026 0.0052 0.0541
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0057 0.0188 0.1961
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0044 0.0131 0.0754
Echinococcus multilocularis smad 0.0026 0.0054 0.0141
Onchocerca volvulus 0.0019 0.0023 0.0239
Schistosoma mansoni smad1 5 8 and 0.0026 0.0054 0.0141
Brugia malayi cathepsin B-like cysteine proteinase 0.0018 0.0018 0.0103
Trypanosoma cruzi cysteine proteinase, putative 0.004 0.0113 0.0201
Toxoplasma gondii sarco/endoplasmic reticulum Ca2+-ATPase 0.0118 0.0455 0.164
Schistosoma mansoni multiple ankyrin repeats single kh domain protein 0.0088 0.0325 0.0847
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0053 0.0171 0.0304
Schistosoma mansoni loxhd1 0.0019 0.0023 0.006
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0057 0.0188 0.1961
Schistosoma mansoni smad 0.0026 0.0054 0.0141
Trichomonas vaginalis mercuric reductase, putative 0.0053 0.0171 0.1784
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0018 0.0018 0.0047
Loa Loa (eye worm) hypothetical protein 0.0022 0.0033 0.0168
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0056 0.0183 0.1906
Brugia malayi MH1 domain containing protein 0.0015 0.0002 0.0013
Trichomonas vaginalis CMGC family protein kinase 0.005 0.0157 0.1639
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.035 0.1472 0.2055
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0018 0.0018 0.0047
Echinococcus multilocularis high affinity cAMP specific 3',5' cyclic 0.0057 0.0188 0.0491
Loa Loa (eye worm) cytochrome P450 family protein 0.0016 0.0006 0.0032
Brugia malayi intermediate filament protein 0.0026 0.0054 0.0311
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0054 0.0176 0.0458
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0018 0.0018 0.0265
Entamoeba histolytica cysteine proteinase, putative 0.004 0.0113 0.196
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0057 0.0188 0.0678
Echinococcus granulosus nuclear factor of activated T cells 5 0.0072 0.0255 0.0665
Plasmodium vivax DNA repair protein REV1, putative 0.0036 0.0098 0.1598
Entamoeba histolytica cysteine protease, putative 0.0018 0.0018 0.031
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0148 0.0588 0.8458
Brugia malayi cathepsin Z-like cysteine proteinase 0.0018 0.0018 0.0103
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0044 0.0131 0.1891
Echinococcus granulosus cation transporting atpase worm 0.0026 0.0053 0.0139
Brugia malayi MH2 domain containing protein 0.0026 0.0054 0.031
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0044 0.0131 0.0343
Onchocerca volvulus Cathepsin F homolog 0.0056 0.0183 0.1906
Plasmodium vivax thioredoxin reductase, putative 0.0153 0.0611 1
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0018 0.0018 0.0186
Echinococcus multilocularis Ankyrin 0.0014 0.0001 0.0001
Onchocerca volvulus 0.0056 0.0183 0.1906
Mycobacterium leprae PROBABLE CATION-TRANSPORTER ATPASE I CTPI 0.0056 0.0186 0.0259
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0034 0.0087 0.0905
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0057 0.0188 0.1961
Echinococcus multilocularis microtubule associated protein 2 0.0677 0.2906 0.758
Loa Loa (eye worm) animal heme peroxidase 0.0026 0.0052 0.0261
Plasmodium vivax serine-repeat antigen (SERA) 0.0018 0.0018 0.0293
Loa Loa (eye worm) animal heme peroxidase 0.0026 0.0052 0.0261
Schistosoma mansoni tar DNA-binding protein 0.0068 0.0235 0.0613
Plasmodium falciparum serine repeat antigen 9 0.0018 0.0018 0.0293
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0018 0.0018 0.0186
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0019 0.002 0.0072
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0003 0.0031
Echinococcus granulosus cathepsin l cysteine peptidase 0.0056 0.0183 0.0477
Echinococcus multilocularis mitogen activated protein kinase 3 0.005 0.0157 0.041
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0034 0.0087 0.1422
Echinococcus multilocularis dna polymerase kappa 0.0143 0.0566 0.1477
Trypanosoma brucei vacuolar-type Ca2+-ATPase 1 0.0093 0.0347 0.4989
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0053 0.0171 0.2464
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0057 0.0188 0.0491
Onchocerca volvulus Cathepsin L homolog 0.0056 0.0183 0.1906
Entamoeba histolytica cysteine protease, putative 0.0056 0.0183 0.3171
Echinococcus multilocularis Polycystic kidney disease protein 0.0019 0.0023 0.006
Trichomonas vaginalis Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase 0.0018 0.0018 0.0186
Loa Loa (eye worm) hypothetical protein 0.0232 0.0955 0.4794
Entamoeba histolytica cysteine proteinase, putative 0.004 0.0113 0.196
Loa Loa (eye worm) hypothetical protein 0.0122 0.0474 0.2379
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0056 0.0183 0.1906
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0468 0.1992 0.718
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0034 0.0088 0.0914
Trichomonas vaginalis maltase-glucoamylase, putative 0.0035 0.0094 0.0976
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0053 0.0171 0.0171
Onchocerca volvulus 0.0056 0.0183 0.1906
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0053 0.0171 0.0983
Trichomonas vaginalis Clan CA, family C1, cathepsin F-like cysteine peptidase 0.0018 0.0018 0.0186
Brugia malayi Latrophilin receptor protein 2 0.0017 0.0012 0.007
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.035 0.1472 0.2055
Loa Loa (eye worm) calcium-transporting ATPase sarcoplasmic/endoplasmic reticulum type 0.0075 0.0266 0.1333
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0016 0.0006 0.0006
Echinococcus granulosus sulfide:quinone oxidoreductase 0.0014 0.0000033761 0.0000088073
Schistosoma mansoni phosphoserine phosphatase 0.0017 0.0011 0.0028
Schistosoma mansoni cgmp-dependent 35-cyclic phosphodiesterase 0.0057 0.0188 0.0491
Loa Loa (eye worm) hypothetical protein 0.0034 0.0087 0.0436
Echinococcus multilocularis cation transporting atpase worm 0.0026 0.0053 0.0139
Trichomonas vaginalis cation-transporting ATPase, putative 0.0118 0.0455 0.4744
Trypanosoma cruzi calcium-translocating P-type ATPase, putative 0.0065 0.0223 0.0397
Loa Loa (eye worm) phosphatidylinositol 3 0.0015 0.0003 0.0015
Leishmania major alpha glucosidase II subunit, putative 0.0035 0.0094 0.1347
Echinococcus granulosus tumor protein p63 0.0331 0.1391 0.3629
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0057 0.0188 0.0334
Mycobacterium tuberculosis Probable oxidoreductase 0.0389 0.1643 0.2294
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.016 0.0639 0.3206
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0018 0.0186
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0056 0.0183 0.1906
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0082 0.0296 0.1697
Loa Loa (eye worm) blistered cuticle protein 3 0.0026 0.0052 0.0261
Entamoeba histolytica deoxycytidyl transferase, putative 0.0117 0.0452 0.7833
Echinococcus granulosus plasma membrane calcium transporting ATPase 0.0077 0.0274 0.0714
Entamoeba histolytica hypothetical protein 0.0146 0.0577 1
Trypanosoma cruzi cysteine peptidase, putative 0.004 0.0113 0.0201
Giardia lamblia Cathepsin B precursor 0.0018 0.0018 0.009
Brugia malayi Type III restriction enzyme, res subunit family protein 0.0034 0.0087 0.0499
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0057 0.0188 0.0334
Schistosoma mansoni alpha-glucosidase 0.0137 0.0541 0.1412
Trypanosoma brucei cAMP-specific phosphodiesterase, putative 0.0057 0.0188 0.2709
Echinococcus multilocularis Niemann Pick C1 protein 0.0138 0.0543 0.1417
Echinococcus granulosus microtubule associated protein 2 0.0677 0.2906 0.758
Schistosoma mansoni glutamate synthase 0.0014 0.0000033761 0.0000088073
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0056 0.0183 0.1906
Mycobacterium ulcerans DNA polymerase IV 0.0143 0.0566 0.0566
Loa Loa (eye worm) hypothetical protein 0.0034 0.0087 0.0436
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0082 0.0853
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0034 0.0087 0.1506
Plasmodium falciparum cGMP-specific phosphodiesterase 0.0057 0.0188 0.3081
Echinococcus multilocularis neuropeptide receptor A26 0.046 0.1954 0.5097
Loa Loa (eye worm) CYP4Cod1 0.0016 0.0006 0.0032
Onchocerca volvulus 0.0233 0.096 1
Echinococcus multilocularis RUN 0.0019 0.0023 0.006
Brugia malayi Pre-SET motif family protein 0.0205 0.0836 0.4798
Entamoeba histolytica myb-like DNA-binding domain containing protein 0.006 0.0199 0.3452
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0057 0.0188 0.0678
Echinococcus granulosus histone lysine methyltransferase setb 0.003 0.0069 0.0181
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0018 0.0186
Echinococcus granulosus Ankyrin 0.0014 0.0001 0.0001
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0056 0.0183 0.1906
Giardia lamblia Myb 1-like protein 0.006 0.02 0.1006
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0148 0.0588 0.8458
Trypanosoma brucei DNA polymerase kappa, putative 0.0062 0.0212 0.3051
Trypanosoma cruzi major cysteine proteinase, putative 0.011 0.0423 0.075
Echinococcus multilocularis plasma membrane calcium transporting ATPase 0.0077 0.0274 0.0714
Entamoeba histolytica cysteine protease, putative 0.004 0.0113 0.196
Trypanosoma brucei DNA polymerase kappa, putative 0.0143 0.0566 0.815
Leishmania major cysteine peptidase A (CPA) 0.0056 0.0183 0.2633
Onchocerca volvulus Cathepsin L homolog 0.0018 0.0018 0.0186
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0069 0.0181
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.0093 0.0347 0.3612
Brugia malayi cathepsin L precursor 0.0018 0.0018 0.0103
Trypanosoma cruzi plasma membrane Ca2+ ATPase 0.0093 0.0347 0.0616
Schistosoma mansoni cathepsin B (C01 family) 0.0018 0.0018 0.0047
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.0014 0.000000016131 0.00000004208
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.0019 0.002 0.0328
Schistosoma mansoni peroxidasin 0.0026 0.0052 0.0136
Brugia malayi latrophilin 2 splice variant baaae 0.0036 0.0098 0.0562
Echinococcus multilocularis Alpha N acetylgalactosaminidase 0.01 0.0379 0.0988
Echinococcus granulosus cation transporting ATPase 13A3 0.0026 0.0053 0.0139
Giardia lamblia Cathepsin B precursor 0.0018 0.0018 0.009
Onchocerca volvulus 0.0056 0.0183 0.1906
Schistosoma mansoni cpg binding protein 0.003 0.0069 0.0179
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0015 0.0003 0.0042
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0056 0.0183 0.1906
Entamoeba histolytica cysteine proteinase, putative 0.0034 0.0088 0.152
Trypanosoma brucei DNA damage repair protein, putative 0.0036 0.0098 0.1405
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0057 0.0188 0.0678
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0056 0.0183 0.1906
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0056 0.0183 0.1906
Onchocerca volvulus Peroxidase homolog 0.0026 0.0052 0.0541
Loa Loa (eye worm) heterochromatin protein 1 0.015 0.0596 0.2993
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0043 0.0443
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.0057 0.0188 0.1961
Brugia malayi RNA binding protein 0.0068 0.0235 0.135
Echinococcus granulosus dna polymerase kappa 0.0143 0.0566 0.1477
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0098 0.0173
Leishmania major vacuolar-type Ca2 -ATPase, putative 0.0093 0.0347 0.4989
Plasmodium vivax serine-repeat antigen 4 (SERA) 0.0018 0.0018 0.0293
Trypanosoma brucei cAMP-specific phosphodiesterase 0.0057 0.0188 0.2709
Trypanosoma cruzi DNA polymerase kappa, putative 0.0143 0.0566 0.1006
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0056 0.0183 0.0918
Giardia lamblia GTOR 0.0044 0.0131 0.066
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0018 0.0018 0.0186
Schistosoma mansoni hypothetical protein 0.0401 0.1697 0.4427
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0117 0.0452 0.1179
Echinococcus granulosus chromobox protein 2 0.0034 0.0087 0.0227
Entamoeba histolytica plasma membrane calcium-transporting ATPase, putative 0.002 0.0025 0.0425
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0148 0.0588 0.8458
Trypanosoma brucei DNA polymerase kappa, putative 0.0143 0.0566 0.815
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0034 0.0088 0.0914
Trypanosoma brucei hypothetical protein, conserved 0.0023 0.0039 0.0557
Schistosoma mansoni disulfide oxidoreductase 0.0014 0.0000033761 0.0000088073
Echinococcus multilocularis NADPH:adrenodoxin oxidoreductase 0.0014 0.0000033761 0.0000088073
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0018 0.0018 0.009
Trypanosoma brucei DNA polymerase kappa, putative 0.0143 0.0566 0.815
Brugia malayi Intermediate filament tail domain containing protein 0.0026 0.0054 0.0311
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0057 0.0188 0.0334
Toxoplasma gondii LsmAD domain-containing protein 0.005 0.0159 0.0573
Leishmania major cathepsin L-like protease 0.0056 0.0183 0.2633
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0018 0.0018 0.0032
Mycobacterium leprae PROBABLE CATION-TRANSPORTER P-TYPE ATPASE B CTPB 0.0026 0.0053 0.0074
Loa Loa (eye worm) hypothetical protein 0.0062 0.0212 0.1064
Toxoplasma gondii P-type ATPase4, putative 0.0083 0.0302 0.109
Schistosoma mansoni cellular tumor antigen P53 0.0048 0.0151 0.0394
Echinococcus multilocularis thioredoxin glutathione reductase 0.0153 0.0611 0.1593
Trichomonas vaginalis r2r3-MYB transcription factor, putative 0.006 0.0199 0.2075
Echinococcus granulosus Ca2 transporting ATPase plasma membrane 0.0077 0.0274 0.0714
Entamoeba histolytica hypothetical protein 0.0146 0.0577 1
Loa Loa (eye worm) hypothetical protein 0.0026 0.0052 0.0261
Echinococcus multilocularis phosphoserine phosphatase 0.0017 0.0011 0.0028
Echinococcus multilocularis calcium transporting atpase 0.0101 0.0382 0.0998
Echinococcus multilocularis cysteine protease 0.0056 0.0183 0.0477
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.004 0.0113 0.1628
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0057 0.0188 0.1961
Brugia malayi haloacid dehalogenase-like hydrolase family protein 0.0047 0.0143 0.0823
Loa Loa (eye worm) cathepsin B 0.0018 0.0018 0.009
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0024 0.0044 0.0635
Brugia malayi M-phase phosphoprotein, mpp8 0.0122 0.0473 0.2717
Echinococcus granulosus Niemann Pick C1 protein 0.0138 0.0543 0.1417
Trichomonas vaginalis r2r3-MYB transcription factor, putative 0.006 0.0199 0.2075
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.003 0.0069 0.0181
Trypanosoma brucei copper-transporting ATPase-like protein, putative 0.0026 0.0053 0.0765
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0023 0.0039 0.0054
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0061 0.0205 0.0534
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.0018 0.0018 0.0047
Echinococcus granulosus peroxidasin 0.0026 0.0052 0.0136
Trypanosoma cruzi plasma membrane Ca2+ ATPase 0.0093 0.0347 0.0616
Echinococcus multilocularis chromodomain helicase DNA binding protein 1 0.0034 0.0087 0.0227
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.01 0.0379 0.0988
Trypanosoma cruzi DNA polymerase kappa, putative 0.0143 0.0566 0.1006
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.004 0.0115 0.1197
Loa Loa (eye worm) hypothetical protein 0.0018 0.0018 0.009
Echinococcus granulosus L aminoadipate semialdehyde 0.0082 0.0296 0.0771
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0056 0.0183 0.2995
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.004 0.0115 0.1197
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0057 0.0188 0.108
Schistosoma mansoni camp/cgmp cyclic nucleotide phosphodiesterase 0.0057 0.0188 0.0491
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0044 0.0131 0.2278
Toxoplasma gondii E1-E2 ATPase subfamily protein 0.0036 0.0097 0.035
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0034 0.0087 0.1506
Schistosoma mansoni hypothetical protein 0.0034 0.0087 0.0227
Trichomonas vaginalis conserved hypothetical protein 0.0057 0.0188 0.1961
Trypanosoma cruzi calcium-translocating P-type ATPase, putative 0.0036 0.0097 0.0173
Loa Loa (eye worm) hypothetical protein 0.005 0.0157 0.0788
Brugia malayi E1-E2 ATPase family protein 0.0026 0.0053 0.0305
Plasmodium vivax multidomain scavenger receptor, putative 0.0019 0.0023 0.0375
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.0087 0.0905
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0069 0.0181
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.0077 0.0274 0.2854
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0035 0.0094 0.0337
Plasmodium falciparum copper-transporting ATPase 0.0026 0.0053 0.087
Trypanosoma brucei DNA polymerase kappa, putative 0.0087 0.0321 0.4617
Loa Loa (eye worm) nuclear factor I 0.0015 0.0002 0.0011
Trichomonas vaginalis C-MYB, putative 0.006 0.0199 0.2075
Trichomonas vaginalis PIKK family atypical protein kinase 0.003 0.0068 0.0706
Loa Loa (eye worm) hypothetical protein 0.0082 0.0296 0.1484
Leishmania major trypanothione reductase 0.0153 0.0611 0.879
Brugia malayi cathepsin F-like cysteine proteinase 0.0022 0.0033 0.0192
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.0468 0.1992 0.5197
Brugia malayi cytoplasmic intermediate filament protein 0.0014 0 0.0002
Trichomonas vaginalis r2r3-MYB transcription factor, putative 0.006 0.0199 0.2075
Giardia lamblia Encystation-specific protease 0.0018 0.0018 0.009
Trypanosoma brucei DNA polymerase eta, putative 0.0172 0.0695 1
Echinococcus granulosus mothers against decapentaplegic 5 0.0026 0.0054 0.0141
Mycobacterium ulcerans metal cation-transporting p-type ATPase CtpC 0.0026 0.0053 0.0053
Loa Loa (eye worm) hypothetical protein 0.0019 0.0023 0.0115
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0018 0.0018 0.031
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.005 0.0157 0.2264
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0056 0.0183 0.1906
Plasmodium falciparum ataxin-2 like protein, putative 0.005 0.0159 0.2605
Schistosoma mansoni type V p-type atpase isoform 0.0026 0.0053 0.0139
Trypanosoma brucei DNA polymerase kappa, putative 0.0143 0.0566 0.815
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0015 0.0003 0.0005
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0014 0.0000033761 0.0000088073
Brugia malayi Probable calcium-transporting ATPase KIAA0703 0.0075 0.0266 0.1525
Echinococcus multilocularis Ca2+ transporting ATPase plasma membrane 0.0077 0.0274 0.0714
Schistosoma mansoni cpg binding protein 0.0028 0.0062 0.0161
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0057 0.0188 0.0678
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0389 0.1643 0.2294
Schistosoma mansoni ankyrin 23/unc44 0.0014 0.000000016131 0.00000004208
Onchocerca volvulus 0.0026 0.0054 0.0564
Trichomonas vaginalis DNA helicase recq1, putative 0.0045 0.0137 0.1423
Brugia malayi Doublecortin family protein 0.0019 0.0023 0.0132
Loa Loa (eye worm) hypothetical protein 0.012 0.0465 0.2334
Echinococcus granulosus geminin 0.0888 0.3833 1
Mycobacterium ulcerans metal cation transporter ATPase p-type CtpE 0.0026 0.0053 0.0053
Loa Loa (eye worm) hypothetical protein 0.0027 0.0055 0.0276
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0053 0.0171 0.2803
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0148 0.0588 0.8458
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0148 0.0588 0.8458
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.0018 0.0018 0.0047
Schistosoma mansoni cation-transporting ATPase 0.0026 0.0053 0.0139
Chlamydia trachomatis metal transport ATPase 0.0026 0.0053 0.0053
Echinococcus granulosus tar DNA binding protein 0.0068 0.0235 0.0613
Schistosoma mansoni hypothetical protein 0.0017 0.0012 0.0032
Trichomonas vaginalis CMGC family protein kinase 0.005 0.0157 0.1639
Onchocerca volvulus 0.0026 0.0052 0.0541
Echinococcus granulosus cysteine protease 0.004 0.0113 0.0295
Trichomonas vaginalis cAMP/cGMP cyclic nucleotide phosphodiesterase, putative 0.0057 0.0188 0.1961
Schistosoma mansoni intermediate filament proteins 0.0026 0.0054 0.0141
Onchocerca volvulus 0.0019 0.0023 0.0239
Giardia lamblia Cathepsin L precursor 0.0018 0.0018 0.009
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0057 0.0188 0.0491
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0148 0.0588 0.8458
Leishmania major cytochrome p450-like protein 0.0016 0.0006 0.009
Mycobacterium tuberculosis Probable UDP-N-acetylglucosamine 1-carboxyvinyltransferase MurA 0.1647 0.7163 1
Wolbachia endosymbiont of Brugia malayi 4'-phosphopantetheinyl transferase 0.0023 0.0039 0.0039
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0018 0.0018 0.0186
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0023 0.0039 0.0634
Mycobacterium ulcerans metal cation transporter p-type ATPase a 0.0083 0.0302 0.0302
Plasmodium falciparum serine repeat antigen 2 0.0018 0.0018 0.0293
Leishmania major cAMP-specific phosphodiesterase, putative 0.0057 0.0188 0.2709
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.0094 0.0976
Echinococcus granulosus cathepsin L cysteine protease 0.004 0.0113 0.0295
Trypanosoma cruzi PAB1-binding protein , putative 0.005 0.0159 0.0282
Entamoeba histolytica plasma membrane calcium ion-transporting ATPase, putative 0.0046 0.0141 0.2451
Schistosoma mansoni tar DNA-binding protein 0.0068 0.0235 0.0613
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.0468 0.1992 0.5197
Leishmania major DNA polymerase eta, putative 0.0172 0.0695 1
Brugia malayi E1-E2 ATPase family protein 0.0053 0.017 0.0976
Trypanosoma cruzi cytochrome P450, putative 0.0016 0.0006 0.0011
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.003 0.0069 0.0181
Schistosoma mansoni chromobox protein 0.015 0.0596 0.1555
Echinococcus multilocularis cAMP and cAMP inhibited cGMP 3',5' cyclic 0.0057 0.0188 0.0491
Trypanosoma brucei unspecified product 0.0081 0.0292 0.4209
Onchocerca volvulus 0.0056 0.0183 0.1906
Loa Loa (eye worm) E1-E2 ATPase 0.0053 0.017 0.0853
Trichomonas vaginalis sucrase-isomaltase, putative 0.0035 0.0094 0.0976
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0028 0.0062 0.0161
Schistosoma mansoni hypothetical protein 0.0051 0.0161 0.0419
Echinococcus granulosus TGF beta signal transducer SmadC 0.0026 0.0054 0.0141
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0148 0.0588 0.8458
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0057 0.0188 0.1961
Echinococcus multilocularis bloom syndrome protein 0.0045 0.0137 0.0356
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0018 0.0018 0.0293
Toxoplasma gondii melibiase subfamily protein 0.01 0.0379 0.1365
Echinococcus multilocularis Chromo domain 0.0034 0.0087 0.0227
Loa Loa (eye worm) hypothetical protein 0.0019 0.002 0.0101
Entamoeba histolytica cysteine protease, putative 0.004 0.0113 0.196
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0034 0.0087 0.0313
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0053 0.0171 0.0447
Schistosoma mansoni cpg binding protein 0.003 0.0069 0.0179
Echinococcus granulosus lipoxygenase domain containing protein 0.0019 0.0023 0.006
Brugia malayi cathepsin Z-like cysteine proteinase 0.0018 0.0018 0.0103
Echinococcus multilocularis lipoxygenase domain containing protein 0.0019 0.0023 0.006
Giardia lamblia Cathepsin L precursor 0.0018 0.0018 0.009
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0092 0.0957
Loa Loa (eye worm) doublecortin family protein 0.0019 0.0023 0.0115
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0092 0.034 0.1227
Loa Loa (eye worm) hypothetical protein 0.0046 0.0141 0.071
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0053 0.0171 0.0171
Loa Loa (eye worm) CHromoDomain protein family member 0.0036 0.0094 0.0471
Giardia lamblia hypothetical protein 0.0057 0.0188 0.0944
Plasmodium falciparum thioredoxin reductase 0.0153 0.0611 1
Trichomonas vaginalis MYB72, putative 0.006 0.0199 0.2075
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0057 0.0188 0.1961
Entamoeba histolytica cysteine protease, putative 0.004 0.0113 0.196
Entamoeba histolytica cysteine proteinase, putative 0.0056 0.0183 0.3171
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0053 0.0171 0.0304
Mycobacterium ulcerans DNA polymerase IV 0.0143 0.0566 0.0566
Entamoeba histolytica cysteine protease, putative 0.004 0.0113 0.196
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0094 0.0166
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0057 0.0188 0.0678
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0103 0.1075
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0057 0.0188 0.108
Loa Loa (eye worm) hypothetical protein 0.0034 0.0087 0.0436
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0056 0.0183 0.0477
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0069 0.0181
Brugia malayi Smad1 0.0026 0.0054 0.031
Brugia malayi Blistered cuticle protein 3 0.0026 0.0052 0.0298
Echinococcus granulosus chromobox protein 1 0.015 0.0596 0.1555
Brugia malayi Uncoordinated protein 44 0.0014 0.000000016131 0.000000092586
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.0087 0.0905
Trichomonas vaginalis conserved hypothetical protein 0.0057 0.0188 0.1961
Trichomonas vaginalis calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0057 0.0188 0.1961
Entamoeba histolytica hypothetical protein 0.0034 0.0087 0.1506
Echinococcus granulosus glutamate synthase 0.0014 0.0000033761 0.0000088073
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0057 0.0188 0.0678
Giardia lamblia Potassium-transporting ATPase alpha chain 1 0.0066 0.023 0.1153
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0015 0.0003 0.0008
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0034 0.0087 0.0905
Echinococcus granulosus bloom syndrome protein 0.0045 0.0137 0.0356
Loa Loa (eye worm) MH2 domain-containing protein 0.0026 0.0054 0.0271
Entamoeba histolytica cysteine proteinase 2 0.004 0.0113 0.196
Loa Loa (eye worm) hypothetical protein 0.0022 0.0033 0.0168
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.0094 0.0976
Trypanosoma cruzi calcium motive p-type ATPase, putative 0.0066 0.023 0.0408
Mycobacterium tuberculosis Conserved hypothetical protein 0.0117 0.0452 0.0631
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.0094 0.0976
Echinococcus granulosus cpg binding protein 0.003 0.0069 0.0179
Loa Loa (eye worm) MH1 domain-containing protein 0.0026 0.0054 0.0271
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.004 0.0113 0.1179
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0126 0.0492 0.0874
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.0087 0.0905
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0053 0.0171 0.0304
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0095 0.0355 0.3693
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0117 0.0452 0.1179
Plasmodium falciparum cysteine proteinase falcipain 3 0.0056 0.0183 0.2995
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0053 0.0547
Entamoeba histolytica Plasma membrane calcium-transporting ATPase, putative 0.0093 0.0347 0.6009
Echinococcus granulosus copper transporting ATPase 1 0.0026 0.0053 0.0139
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0036 0.0094 0.0245
Echinococcus multilocularis lipoxygenase domain containing protein 0.0019 0.0023 0.006
Echinococcus multilocularis tar DNA binding protein 0.0068 0.0235 0.0613
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.004 0.0115 0.1197
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0082 0.0853
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0057 0.0188 0.0678
Schistosoma mansoni hypothetical protein 0.004 0.0113 0.0296
Brugia malayi Animal haem peroxidase family protein 0.0026 0.0052 0.0298
Echinococcus multilocularis dna polymerase eta 0.0172 0.0695 0.1812
Plasmodium falciparum serine repeat antigen 6 0.0018 0.0018 0.0293
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0018 0.0186
Onchocerca volvulus 0.0034 0.0088 0.0914
Schistosoma mansoni hypothetical protein 0.0019 0.0023 0.006
Echinococcus granulosus cathepsin b 0.0018 0.0018 0.0047
Plasmodium falciparum serine repeat antigen 8 0.0018 0.0018 0.0293
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0056 0.0183 0.1906
Brugia malayi Animal haem peroxidase family protein 0.0026 0.0052 0.0298
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.004 0.0113 0.0295
Schistosoma mansoni cathepsin s 0.0022 0.0033 0.0087
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0044 0.0131 0.1891
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0057 0.0188 0.108
Plasmodium vivax calcium-transporting ATPase, putative 0.0118 0.0455 0.7454
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0026 0.0054 0.0272
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0148 0.0588 0.8458
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0057 0.0188 0.1961
Entamoeba histolytica phospholipid-transporting P-type ATPase, putative 0.0026 0.0053 0.0921
Entamoeba histolytica Plasma membrane calcium-transporting ATPase, putative 0.0093 0.0347 0.6009
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0036 0.0098 0.0352
Toxoplasma gondii haloacid dehalogenase family hydrolase domain-containing protein 0.0026 0.0053 0.0191
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0053 0.0171 0.0239
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0019 0.002 0.0115
Loa Loa (eye worm) Smad1 0.0026 0.0054 0.0271
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0054 0.0559
Echinococcus multilocularis expressed conserved protein 0.0091 0.0336 0.0876
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0056 0.0183 0.2995
Plasmodium vivax ataxin-2 like protein, putative 0.005 0.0159 0.2605
Plasmodium vivax serine-repeat antigen 3 (SERA) 0.0018 0.0018 0.0293
Loa Loa (eye worm) fibroinase 0.0056 0.0183 0.0918
Brugia malayi Valyl-tRNA synthetase 0.0034 0.0087 0.0499
Plasmodium vivax P-type ATPase4, putative 0.0118 0.0455 0.7454
Loa Loa (eye worm) hypothetical protein 0.0026 0.0052 0.0261
Trypanosoma cruzi phospholipid-transporting ATPase-like protein, putative 0.0017 0.0011 0.0019
Entamoeba histolytica hypothetical protein 0.0146 0.0577 1
Echinococcus granulosus smad 0.0026 0.0054 0.0141
Trypanosoma cruzi hypothetical protein, conserved 0.0057 0.0188 0.0334
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0018 0.0018 0.009
Entamoeba histolytica cysteine protease, putative 0.004 0.0113 0.196
Echinococcus granulosus cAMP and cAMP inhibited cGMP 3'5' cyclic 0.0057 0.0188 0.0491
Loa Loa (eye worm) hypothetical protein 0.0034 0.0087 0.0436
Brugia malayi calcium ATPase 0.004 0.0115 0.0659
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.004 0.0112 0.1841
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0015 0.0003 0.0042
Brugia malayi Cathepsin L-like precursor 0.0034 0.0088 0.0504
Echinococcus granulosus sarco:endoplasmic reticulum calcium ATPase 0.0118 0.0455 0.1187
Plasmodium falciparum serine repeat antigen 7 0.0018 0.0018 0.0293
Brugia malayi MH1 domain containing protein 0.0026 0.0054 0.031
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0056 0.0183 0.1906
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0023 0.0037 0.0097
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.004 0.0115 0.1197
Loa Loa (eye worm) MH2 domain-containing protein 0.0388 0.1639 0.8226
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0056 0.0183 0.1906
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0019 0.002 0.0052
Brugia malayi MH1 domain containing protein 0.0026 0.0054 0.031
Toxoplasma gondii cathepsin B 0.0018 0.0018 0.0064
Echinococcus multilocularis pyridine nucleotide disulfide oxidoreductase 0.0014 0.0000033761 0.0000088073
Loa Loa (eye worm) hypothetical protein 0.0019 0.0023 0.0115
Echinococcus granulosus cathepsin l1 0.0034 0.0088 0.0229
Brugia malayi fibroinase precursor 0.0018 0.0018 0.0103
Brugia malayi Probable 3',5'-cyclic phosphodiesterase C32E12.2, putative 0.0057 0.0188 0.108
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0015 0.0003 0.0008
Plasmodium falciparum calcium-transporting ATPase 0.0101 0.0382 0.6263
Schistosoma mansoni blooms syndrome DNA helicase 0.0036 0.0095 0.0247
Echinococcus granulosus lysosomal alpha glucosidase 0.016 0.0639 0.1666
Trypanosoma brucei chrX additional, unordered contigs 0.0036 0.0098 0.1405
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0053 0.0171 0.2464
Onchocerca volvulus 0.0026 0.0054 0.0564
Loa Loa (eye worm) thioredoxin reductase 0.0153 0.0611 0.3065
Schistosoma mansoni survival motor neuron protein 0.0047 0.0146 0.038
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0053 0.0172 0.0986
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0056 0.0183 0.1906
Loa Loa (eye worm) hypothetical protein 0.0034 0.0088 0.044
Brugia malayi Cathepsin L-like precursor 0.0056 0.0183 0.105
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0053 0.0171 0.0304
Schistosoma mansoni calcium-transporting atpase 2 (atpase 2) 0.0101 0.0382 0.0998
Onchocerca volvulus 0.0092 0.0343 0.3577
Loa Loa (eye worm) calcium ATPase 0.0057 0.0188 0.0941
Trypanosoma brucei P-type H+-ATPase, putative 0.0053 0.017 0.2446
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0057 0.0188 0.1961
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0057 0.0188 0.1961
Schistosoma mansoni chromobox protein 0.015 0.0596 0.1555
Loa Loa (eye worm) hypothetical protein 0.0026 0.0053 0.0267
Schistosoma mansoni tar DNA-binding protein 0.0068 0.0235 0.0613
Brugia malayi hypothetical protein 0.0033 0.0081 0.0464
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0082 0.0296 0.0771
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0053 0.0171 0.2464
Schistosoma mansoni hypothetical protein 0.0888 0.3833 1
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0034 0.0087 0.0227
Trichomonas vaginalis Heterochromatin protein, putative 0.0034 0.0087 0.0905
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0015 0.0003 0.0042
Echinococcus multilocularis calcium transporting ATPase type 2C member 0.0118 0.0455 0.1187
Loa Loa (eye worm) hypothetical protein 0.003 0.0069 0.0348
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0018 0.0018 0.0032
Brugia malayi Death domain containing protein 0.0014 0.000000016131 0.000000092586
Echinococcus multilocularis neuropeptide s receptor 0.046 0.1954 0.5097
Trypanosoma cruzi cyclic nucleotide phosphodiesterase 0.0057 0.0188 0.0334
Echinococcus multilocularis X box binding protein 1 0.0282 0.1177 0.3071
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0092 0.0957
Trypanosoma brucei vacuolar-type Ca2+-ATPase, putative 0.0093 0.0347 0.4989
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0057 0.0188 0.1961
Echinococcus multilocularis cathepsin L cysteine protease 0.0056 0.0183 0.0477
Schistosoma mansoni hypothetical protein 0.0017 0.0012 0.0032
Brugia malayi Probable 3',5'-cyclic phosphodiesterase R153.1, putative 0.0411 0.1742 1
Echinococcus multilocularis copper transporting ATPase 1 0.0026 0.0053 0.0139
Entamoeba histolytica cysteine proteinase, putative 0.004 0.0113 0.196
Echinococcus granulosus lamin 0.0026 0.0054 0.0141
Echinococcus multilocularis cathepsin L cysteine protease 0.0056 0.0183 0.0477
Brugia malayi Heterochromatin protein 1 0.015 0.0596 0.3422
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0082 0.0853
Echinococcus multilocularis cation transporting ATPase 13A1 0.0026 0.0053 0.0139
Leishmania major vacuolar-type Ca2 -ATPase, putative 0.0093 0.0347 0.4989
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0053 0.0171 0.0171
Loa Loa (eye worm) hypothetical protein 0.0057 0.0188 0.0945
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0017 0.0012 0.0032
Trypanosoma cruzi hypothetical protein, conserved 0.0057 0.0188 0.0334
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0057 0.0188 0.1961
Trypanosoma cruzi hypothetical protein, conserved 0.0057 0.0188 0.0334
Trypanosoma cruzi plasma-membrane proton-efflux P-type ATPase, putative 0.0036 0.0097 0.0173
Echinococcus multilocularis geminin 0.0888 0.3833 1
Mycobacterium leprae conserved hypothetical protein 0.0023 0.0039 0.0054
Echinococcus multilocularis chromobox protein 1 0.015 0.0596 0.1555
Trichomonas vaginalis phospholipid-transporting ATPase, putative 0.0026 0.0053 0.0554
Giardia lamblia Cathepsin B precursor 0.0018 0.0018 0.009
Onchocerca volvulus 0.0122 0.0473 0.4931
Trichomonas vaginalis DNA helicase recq, putative 0.0045 0.0137 0.1423
Loa Loa (eye worm) hypothetical protein 0.0056 0.0183 0.0918
Loa Loa (eye worm) hypothetical protein 0.005 0.0159 0.0799
Echinococcus multilocularis phosphoserine phosphatase 0.0017 0.0011 0.0028
Trichomonas vaginalis CMGC family protein kinase 0.005 0.0157 0.1639
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0015 0.0003 0.0017
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0034 0.0087 0.0313
Echinococcus multilocularis phosphoserine phosphatase 0.0017 0.0011 0.0028
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0056 0.0183 0.0918
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.004 0.0113 0.0295
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0053 0.0171 0.0304
Brugia malayi Papain family cysteine protease containing protein 0.0018 0.0018 0.0103
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0148 0.0588 0.8458
Echinococcus granulosus cathepsin L 0.004 0.0113 0.0295
Echinococcus granulosus high affinity cgmp specific 3' 5' cyclic 0.0057 0.0188 0.0491
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0056 0.0183 0.0477
Toxoplasma gondii NADPH-glutathione reductase 0.0053 0.0171 0.0617
Trypanosoma brucei DNA polymerase kappa, putative 0.0143 0.0566 0.815
Onchocerca volvulus 0.0056 0.0183 0.1906
Trypanosoma brucei PAB1-binding protein , putative 0.005 0.0159 0.229
Loa Loa (eye worm) hypothetical protein 0.0034 0.0087 0.0436
Plasmodium falciparum dipeptidyl aminopeptidase 3 0.0018 0.0018 0.0293
Mycobacterium ulcerans cation-transporter ATPase I CtpI 0.0056 0.0186 0.0186
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0043 0.0443
Brugia malayi Protein kinase domain containing protein 0.0015 0.0002 0.0011
Trypanosoma brucei 3', 5'-cyclic nucleotide phosphodiesterase, putative 0.0057 0.0188 0.2709
Loa Loa (eye worm) hypothetical protein 0.0018 0.0018 0.009
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0042 0.0441
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0089 0.0329 0.3423
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0035 0.0094 0.0976
Schistosoma mansoni glutamate synthase 0.0014 0.0000033761 0.0000088073

Activities

Activity type Activity value Assay description Source Reference
IC50 (functional) = 0.006 uM Inhibitory concentration of vinblastine against the MDR resistant cell line HCT116/VM46 in the presence of 1 mM of the compound ChEMBL. 12729663
IC50 (functional) = 0.006 uM Inhibitory concentration of vinblastine against the MDR resistant cell line HCT116/VM46 in the presence of 1 mM of the compound ChEMBL. 12729663
IC50 (functional) = 0.09 uM Inhibitory concentration of doxorubicin against the MDR resistant cell line HCT116/VM46 in the presence of 1 mM of the compound ChEMBL. 12729663
IC50 (functional) = 0.09 uM Inhibitory concentration of doxorubicin against the MDR resistant cell line HCT116/VM46 in the presence of 1 mM of the compound ChEMBL. 12729663
IC50 (functional) = 40 uM Inhibitory concentration against MDR human carcinoma HCT116/VM46 cell line ChEMBL. 12729663
IC50 (functional) = 40 uM Inhibitory concentration against MDR human carcinoma HCT116/VM46 cell line ChEMBL. 12729663
IC50 (functional) = 100 uM Inhibitory concentration against human carcinoma HCT116 cell line ChEMBL. 12729663
IC50 (functional) = 100 uM Inhibitory concentration against human carcinoma HCT116 cell line ChEMBL. 12729663
Reversion (functional) = 67 % Percent reversion of the compound was determined in HCT116 cell line (IC50(-)/MDR IC50(+) X 100 ChEMBL. 12729663
Reversion (functional) = 67 % Percent reversion of the compound was determined in HCT116 cell line (IC50(-)/MDR IC50(+) X 100 ChEMBL. 12729663
Reversion (functional) = 100 % Percent reversion of the compound was determined in HCT116 cell line (IC50(-)/MDR IC50(+) X 100 ChEMBL. 12729663
Reversion (functional) = 100 % Percent reversion of the compound was determined in HCT116 cell line (IC50(-)/MDR IC50(+) X 100 ChEMBL. 12729663
Sensitivity (functional) = 8 Gain in sensitivity is measured as MDR IC50 (without added drug) / MDR IC50 (with added drug) in MDR HCT116/VM46 cell line ChEMBL. 12729663
Sensitivity (functional) = 17 Gain in sensitivity is measured as MDR IC50 (without added drug) / MDR IC50 (with added drug) in MDR HCT116/VM46 cell line ChEMBL. 12729663

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Homo sapiens ChEMBL23 12729663

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

No external resources registered for this compound

Bibliographic References

1 literature reference was collected for this gene.

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