Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | isoleucyl tRNA synthetase, mitochondrial | 0.0139 | 0.0453 | 0.2965 |
Toxoplasma gondii | threonyl-tRNA synthetase family protein | 0.0054 | 0.0117 | 0.0113 |
Leishmania major | long-chain-fatty-acid-CoA ligase, putative | 0.0028 | 0.0015 | 0.0084 |
Plasmodium vivax | methionine--tRNA ligase, putative | 0.0058 | 0.0135 | 0.2186 |
Chlamydia trachomatis | isoleucine--tRNA ligase | 0.0177 | 0.0601 | 0.3923 |
Mycobacterium ulcerans | arginyl-tRNA synthetase | 0.0031 | 0.0026 | 0.0011 |
Giardia lamblia | Isoleucyl-tRNA synthetase | 0.0177 | 0.0601 | 1 |
Trypanosoma cruzi | methionyl-tRNA synthetase, putative | 0.0058 | 0.0135 | 0.2186 |
Brugia malayi | AMP-binding enzyme family protein | 0.0028 | 0.0015 | 0.0036 |
Brugia malayi | acetyl-Coenzyme A synthetase 2 | 0.0028 | 0.0015 | 0.0036 |
Leishmania major | threonyl-tRNA synthetase, putative | 0.0061 | 0.0146 | 0.2293 |
Mycobacterium leprae | Probable threonyl-tRNA synthetase ThrS (threonine-tRNA synthetase) (ThrRS) (Threonine-tRNA ligase) | 0.0054 | 0.0117 | 0.0102 |
Brugia malayi | bifunctional aminoacyl-tRNA synthetase | 0.0223 | 0.0782 | 0.5527 |
Toxoplasma gondii | tRNA ligases class I (M) protein | 0.0058 | 0.0135 | 0.0131 |
Toxoplasma gondii | isoleucyl-tRNA synthetase family protein | 0.0177 | 0.0601 | 0.0597 |
Echinococcus granulosus | isoleucyl trna synthetase mitochondrial | 0.0139 | 0.0453 | 0.2965 |
Mycobacterium tuberculosis | Possible DNA glycosylase | 0.0104 | 0.0313 | 0.0313 |
Entamoeba histolytica | leucyl-tRNA synthetase, putative | 0.0063 | 0.0152 | 0.0984 |
Plasmodium vivax | isoleucine--tRNA ligase, putative | 0.0177 | 0.0601 | 1 |
Brugia malayi | arginyl aa-tRNA synthetase protein 1 | 0.0031 | 0.0026 | 0.0113 |
Brugia malayi | valyl-tRNA synthetase family protein | 0.0063 | 0.0152 | 0.1016 |
Leishmania major | acetyl-CoA synthetase, putative | 0.0028 | 0.0015 | 0.0084 |
Loa Loa (eye worm) | oxidoreductase | 0.0028 | 0.0015 | 0.0084 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0015 | 0.0084 |
Mycobacterium ulcerans | thioesterase | 0.0373 | 0.137 | 0.1357 |
Mycobacterium leprae | PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSE | 0.0032 | 0.003 | 0.0014 |
Brugia malayi | AMP-binding enzyme family protein | 0.006 | 0.0139 | 0.0924 |
Mycobacterium ulcerans | formamidopyrimidine-DNA glycosylase | 0.0104 | 0.0313 | 0.0299 |
Plasmodium vivax | valine--tRNA ligase, putative | 0.0063 | 0.0152 | 0.248 |
Schistosoma mansoni | arginyl-tRNA synthetase | 0.0031 | 0.0026 | 0.0147 |
Mycobacterium ulcerans | peptide synthetase Nrp (peptide synthase) | 0.006 | 0.0139 | 0.0124 |
Onchocerca volvulus | 0.006 | 0.0139 | 0.2833 | |
Onchocerca volvulus | 0.0063 | 0.0152 | 0.3126 | |
Plasmodium vivax | methionine--tRNA ligase, putative | 0.0058 | 0.0135 | 0.2186 |
Trypanosoma cruzi | arginine N-methyltransferase, type II, putative | 0.0047 | 0.0091 | 0.1464 |
Trichomonas vaginalis | antibiotic synthetase, putative | 0.0028 | 0.0015 | 0.0188 |
Schistosoma mansoni | shk1 kinase-binding protein | 0.0074 | 0.0196 | 0.1289 |
Echinococcus multilocularis | protein arginine N methyltransferase 5 | 0.0074 | 0.0196 | 0.1223 |
Onchocerca volvulus | 0.006 | 0.0139 | 0.2833 | |
Treponema pallidum | isoleucyl-tRNA synthetase | 0.0177 | 0.0601 | 0.4167 |
Mycobacterium ulcerans | valyl-tRNA synthetase | 0.0063 | 0.0152 | 0.0137 |
Schistosoma mansoni | isoleucine--tRNA ligase | 0.0177 | 0.0601 | 0.4012 |
Mycobacterium tuberculosis | Probable valyl-tRNA synthase protein ValS (valyl-tRNA synthetase) (valine--tRNA ligase) (valine translase) | 0.0063 | 0.0152 | 0.0152 |
Trichomonas vaginalis | isoleucyl tRNA synthetase, putative | 0.0177 | 0.0601 | 1 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0037 | 0.005 | 0.0035 |
Echinococcus granulosus | valyl tRNA synthetase | 0.0063 | 0.0152 | 0.0927 |
Treponema pallidum | leucyl-tRNA synthetase | 0.0096 | 0.0283 | 0.186 |
Plasmodium falciparum | leucine--tRNA ligase, putative | 0.0063 | 0.0152 | 0.248 |
Leishmania major | acetyl-CoA synthetase, putative | 0.0028 | 0.0015 | 0.0084 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0037 | 0.005 | 0.0252 |
Trypanosoma cruzi | acetyl-CoA synthetase, putative | 0.0028 | 0.0015 | 0.0188 |
Trypanosoma cruzi | valyl-tRNA synthetase, putative | 0.0038 | 0.0054 | 0.083 |
Trichomonas vaginalis | shk1 kinase-binding protein, putative | 0.0047 | 0.0091 | 0.1464 |
Echinococcus multilocularis | Threonyl tRNA synthetase, C | 0.0061 | 0.0146 | 0.0884 |
Echinococcus multilocularis | valyl tRNA synthetase | 0.0063 | 0.0152 | 0.0927 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0028 | 0.0015 | 0.0015 |
Mycobacterium ulcerans | formamidopyrimidine-DNA glycosylase | 0.0104 | 0.0313 | 0.0299 |
Plasmodium falciparum | isoleucine--tRNA ligase, putative | 0.0177 | 0.0601 | 1 |
Mycobacterium ulcerans | pantoate--beta-alanine ligase | 0.2572 | 1 | 1 |
Mycobacterium tuberculosis | P-hydroxybenzoyl-AMP ligase FadD22 | 0.0037 | 0.005 | 0.005 |
Trypanosoma cruzi | valyl-tRNA synthetase, putative | 0.0063 | 0.0152 | 0.248 |
Trypanosoma brucei | methionyl-tRNA synthetase, putative | 0.0058 | 0.0135 | 0.2037 |
Brugia malayi | AMP-binding enzyme family protein | 0.0028 | 0.0015 | 0.0036 |
Echinococcus multilocularis | leucyl tRNA synthetase | 0.0063 | 0.0152 | 0.0927 |
Mycobacterium ulcerans | methionyl-tRNA synthetase | 0.0058 | 0.0135 | 0.0119 |
Echinococcus multilocularis | valyl tRNA synthetase | 0.0063 | 0.0152 | 0.0927 |
Leishmania major | valyl-tRNA synthetase, putative | 0.0063 | 0.0152 | 0.2401 |
Trichomonas vaginalis | isoleucyl, leucyl, tyrosyl, valyl and methionyl-tRNA synthetases, putative | 0.0038 | 0.0054 | 0.083 |
Echinococcus granulosus | valyl tRNA synthetase | 0.0063 | 0.0152 | 0.0927 |
Trypanosoma brucei | valyl-tRNA synthetase, putative | 0.0063 | 0.0152 | 0.2336 |
Brugia malayi | AMP-binding enzyme family protein | 0.0028 | 0.0015 | 0.0036 |
Toxoplasma gondii | isoleucyl-tRNA synthetase, putative | 0.0063 | 0.0152 | 0.0148 |
Toxoplasma gondii | tRNA synthetase, putative | 0.0063 | 0.0152 | 0.0148 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0015 | 0.0084 |
Trichomonas vaginalis | leucyl-tRNA synthetase, putative | 0.0063 | 0.0152 | 0.248 |
Echinococcus multilocularis | glycyl tRNA synthetase | 0.0223 | 0.0782 | 0.519 |
Loa Loa (eye worm) | hypothetical protein | 0.0096 | 0.0283 | 0.2079 |
Trichomonas vaginalis | leucyl-tRNA synthetase, putative | 0.0038 | 0.0054 | 0.083 |
Loa Loa (eye worm) | multisynthetase complex auxiliary component p43 | 0.0324 | 0.1177 | 0.8755 |
Treponema pallidum | threonyl-tRNA synthetase | 0.0054 | 0.0117 | 0.0661 |
Giardia lamblia | Leucyl-tRNA synthetase | 0.0083 | 0.0233 | 0.3772 |
Mycobacterium tuberculosis | Pantoate--beta-alanine ligase PanC (pantothenate synthetase) (pantoate activating enzyme) | 0.2572 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0045 | 0.0304 |
Entamoeba histolytica | Skb1 methyltransferase, putative | 0.0074 | 0.0196 | 0.1298 |
Echinococcus granulosus | Threonyl tRNA synthetase C | 0.0061 | 0.0146 | 0.0884 |
Echinococcus granulosus | leucyl tRNA synthetase | 0.0063 | 0.0152 | 0.0927 |
Mycobacterium leprae | Probable methionyl-tRNA synthase MetS | 0.0058 | 0.0135 | 0.0119 |
Wolbachia endosymbiont of Brugia malayi | isoleucyl-tRNA synthetase | 0.0177 | 0.0601 | 1 |
Leishmania major | isoleucyl-tRNA synthetase, putative | 0.0177 | 0.0601 | 1 |
Loa Loa (eye worm) | AMP-binding enzyme family protein | 0.0028 | 0.0015 | 0.0084 |
Loa Loa (eye worm) | AMP-binding enzyme family protein | 0.006 | 0.0139 | 0.1009 |
Giardia lamblia | Valine-tRNA ligase | 0.0063 | 0.0152 | 0.2401 |
Mycobacterium ulcerans | non-ribosomal peptide synthetase MbtE | 0.006 | 0.0139 | 0.0124 |
Toxoplasma gondii | valyl-tRNA synthetase | 0.0063 | 0.0152 | 0.0148 |
Brugia malayi | isoleucyl-tRNA synthetase family protein | 0.0177 | 0.0601 | 0.4233 |
Plasmodium falciparum | valine--tRNA ligase, putative | 0.0063 | 0.0152 | 0.248 |
Schistosoma mansoni | threonyl-tRNA synthetase | 0.0049 | 0.0097 | 0.0624 |
Mycobacterium tuberculosis | Peptide synthetase MbtF (peptide synthase) | 0.006 | 0.0139 | 0.0139 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0028 | 0.0015 | 0.0015 |
Schistosoma mansoni | methyltransferase-related | 0.0027 | 0.001 | 0.0042 |
Schistosoma mansoni | valine-tRNA ligase | 0.0063 | 0.0152 | 0.0995 |
Trypanosoma cruzi | leucyl-tRNA synthetase, putative | 0.0063 | 0.0152 | 0.248 |
Plasmodium falciparum | arginine--tRNA ligase | 0.0031 | 0.0026 | 0.0367 |
Plasmodium falciparum | methionine--tRNA ligase, putative | 0.0058 | 0.0135 | 0.2186 |
Mycobacterium tuberculosis | Conserved protein | 0.0027 | 0.001 | 0.001 |
Echinococcus multilocularis | leucyl tRNA synthetase | 0.0121 | 0.0381 | 0.2478 |
Trichomonas vaginalis | antibiotic synthetase, putative | 0.0028 | 0.0015 | 0.0188 |
Plasmodium falciparum | isoleucine--tRNA ligase, putative | 0.0167 | 0.056 | 0.9312 |
Brugia malayi | AMP-binding enzyme family protein | 0.0035 | 0.0045 | 0.0247 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0028 | 0.0015 | 0.0084 |
Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0037 | 0.005 | 0.0287 |
Echinococcus multilocularis | methionine tRNA synthetase | 0.0058 | 0.0135 | 0.0808 |
Trypanosoma brucei | arginine N-methyltransferase, type II | 0.0047 | 0.0091 | 0.1301 |
Leishmania major | arginyl-tRNA synthetase, putative | 0.0031 | 0.0026 | 0.0266 |
Loa Loa (eye worm) | hypothetical protein | 0.0177 | 0.0601 | 0.4456 |
Mycobacterium tuberculosis | Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0028 | 0.0015 | 0.0015 |
Giardia lamblia | Threonyl-tRNA synthetase | 0.0054 | 0.0117 | 0.1811 |
Chlamydia trachomatis | valine--tRNA ligase | 0.0063 | 0.0152 | 0.086 |
Echinococcus granulosus | methionyl tRNA synthetase cytoplasmic | 0.0404 | 0.1492 | 1 |
Trypanosoma brucei | threonyl-tRNA synthetase, putative | 0.0061 | 0.0146 | 0.2227 |
Brugia malayi | AMP-binding enzyme family protein | 0.0028 | 0.0015 | 0.0036 |
Leishmania major | leucyl-tRNA synthetase, putative | 0.0121 | 0.0381 | 0.6278 |
Mycobacterium tuberculosis | Probable threonyl-tRNA synthetase ThrS (threonine-tRNA synthetase)(ThrRS) (threonine-tRNA ligase) | 0.0054 | 0.0117 | 0.0117 |
Toxoplasma gondii | leucyl-tRNA synthetase (LeuRS2) | 0.0063 | 0.0152 | 0.0148 |
Plasmodium vivax | threonine--tRNA ligase, putative | 0.0054 | 0.0117 | 0.1896 |
Wolbachia endosymbiont of Brugia malayi | methionyl-tRNA synthetase | 0.0058 | 0.0135 | 0.1888 |
Plasmodium falciparum | methionine--tRNA ligase | 0.0058 | 0.0135 | 0.2186 |
Echinococcus granulosus | isoleucyl tRNA synthetase, cytoplasmic | 0.0177 | 0.0601 | 0.3967 |
Mycobacterium tuberculosis | Probable peptide synthetase Nrp (peptide synthase) | 0.006 | 0.0139 | 0.0139 |
Echinococcus granulosus | protein arginine N methyltransferase 5 | 0.0074 | 0.0196 | 0.1223 |
Treponema pallidum | methionyl-tRNA synthetase | 0.0382 | 0.1406 | 1 |
Plasmodium vivax | acetyl-CoA synthetase, putative | 0.0028 | 0.0015 | 0.0188 |
Mycobacterium tuberculosis | Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) | 0.0028 | 0.0015 | 0.0015 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0028 | 0.0015 | 0.0084 |
Brugia malayi | methionyl-tRNA synthetase | 0.0058 | 0.0135 | 0.0891 |
Mycobacterium tuberculosis | Hypothetical protein | 0.0027 | 0.001 | 0.001 |
Brugia malayi | AMP-binding enzyme family protein | 0.0028 | 0.0015 | 0.0036 |
Onchocerca volvulus | 0.0139 | 0.0453 | 1 | |
Entamoeba histolytica | threonyl-tRNA synthetase, putative | 0.0054 | 0.0117 | 0.0733 |
Mycobacterium ulcerans | phenolpthiocerol synthesis type-I polyketide synthase PpsE | 0.0032 | 0.003 | 0.0014 |
Mycobacterium tuberculosis | Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0028 | 0.0015 | 0.0015 |
Plasmodium vivax | protein arginine N-methyltransferase 5, putative | 0.0074 | 0.0196 | 0.3212 |
Echinococcus granulosus | glycyl tRNA synthetase | 0.0223 | 0.0782 | 0.519 |
Trichomonas vaginalis | valyl-tRNA synthetase, putative | 0.0038 | 0.0054 | 0.083 |
Trichomonas vaginalis | leucyl-tRNA synthetase, putative | 0.0063 | 0.0152 | 0.248 |
Mycobacterium tuberculosis | Isoleucyl-tRNA synthetase IleS | 0.0114 | 0.0354 | 0.0354 |
Schistosoma mansoni | isoleucine--tRNA ligase | 0.0177 | 0.0601 | 0.4012 |
Loa Loa (eye worm) | hypothetical protein | 0.0083 | 0.0233 | 0.1709 |
Toxoplasma gondii | leucyl-tRNA synthetase | 0.0063 | 0.0152 | 0.0148 |
Onchocerca volvulus | 0.0038 | 0.0054 | 0.0875 | |
Trypanosoma cruzi | acetyl-CoA synthetase, putative | 0.0028 | 0.0015 | 0.0188 |
Loa Loa (eye worm) | hypothetical protein | 0.0139 | 0.0453 | 0.3351 |
Plasmodium falciparum | protein arginine N-methyltransferase 5, putative | 0.0074 | 0.0196 | 0.3212 |
Leishmania major | arginine N-methyltransferase, type II, putative;with=GeneDB:Tb927.10.640 | 0.0047 | 0.0091 | 0.1374 |
Schistosoma mansoni | methionine-tRNA synthetase | 0.0058 | 0.0135 | 0.0877 |
Chlamydia trachomatis | leucine--tRNA ligase | 0.0096 | 0.0283 | 0.1751 |
Trypanosoma brucei | arginyl-tRNA synthetase, putative | 0.0031 | 0.0026 | 0.0183 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0028 | 0.0015 | 0.0084 |
Mycobacterium leprae | isoleucyl-tRNA synthetase IleS | 0.0177 | 0.0601 | 0.0587 |
Trypanosoma cruzi | isoleucyl-tRNA synthetase, putative | 0.0177 | 0.0601 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0015 | 0.0084 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0027 | 0.001 | 0.0104 |
Loa Loa (eye worm) | hypothetical protein | 0.0366 | 0.1344 | 1 |
Giardia lamblia | Methionyl-tRNA synthetase | 0.0058 | 0.0135 | 0.2104 |
Toxoplasma gondii | Acetyl-coenzyme A synthetase 2, putative | 0.0028 | 0.0015 | 0.0011 |
Chlamydia trachomatis | threonine--tRNA ligase | 0.0061 | 0.0146 | 0.0817 |
Mycobacterium ulcerans | leucyl-tRNA synthetase | 0.0096 | 0.0283 | 0.0268 |
Brugia malayi | threonyl-tRNA synthetase, cytoplasmic | 0.0061 | 0.0146 | 0.0971 |
Brugia malayi | leucyl-tRNA synthetase | 0.0063 | 0.0152 | 0.1016 |
Entamoeba histolytica | methionyl-tRNA synthetase, putative | 0.0382 | 0.1406 | 1 |
Brugia malayi | methionyl-tRNA synthetase | 0.0382 | 0.1406 | 1 |
Treponema pallidum | valyl-tRNA synthetase | 0.0063 | 0.0152 | 0.0914 |
Loa Loa (eye worm) | isoleucyl-tRNA synthetase | 0.0177 | 0.0601 | 0.4456 |
Loa Loa (eye worm) | methionyl-tRNA synthetase | 0.0058 | 0.0135 | 0.0974 |
Toxoplasma gondii | pantoate-beta-alanine ligase | 0.2572 | 1 | 1 |
Schistosoma mansoni | methionine-tRNA synthetase | 0.0404 | 0.1492 | 1 |
Mycobacterium leprae | Probable formamidopyrimidine-DNA glycosylase Fpg (FAPY-DNA GLYCOSYLASE) | 0.0104 | 0.0313 | 0.0299 |
Brugia malayi | isoleucyl-tRNA synthetase | 0.0177 | 0.0601 | 0.4233 |
Trypanosoma cruzi | long-chain-fatty-acid-CoA ligase, putative | 0.0028 | 0.0015 | 0.0188 |
Entamoeba histolytica | valyl tRNA synthetase, putative | 0.0063 | 0.0152 | 0.0984 |
Mycobacterium tuberculosis | Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase | 0.1709 | 0.6613 | 0.6613 |
Trypanosoma brucei | isoleucyl-tRNA synthetase, putative | 0.0177 | 0.0601 | 1 |
Schistosoma mansoni | leucyl-tRNA synthetase | 0.0121 | 0.0381 | 0.2534 |
Brugia malayi | Valyl-tRNA synthetase | 0.0063 | 0.0152 | 0.1016 |
Toxoplasma gondii | propionate-CoA ligase | 0.0028 | 0.0015 | 0.0011 |
Plasmodium vivax | hypothetical protein, conserved | 0.0121 | 0.0381 | 0.6316 |
Mycobacterium ulcerans | isoleucyl-tRNA synthetase | 0.0177 | 0.0601 | 0.0587 |
Wolbachia endosymbiont of Brugia malayi | leucyl-tRNA synthetase | 0.0121 | 0.0381 | 0.6176 |
Wolbachia endosymbiont of Brugia malayi | threonyl-tRNA synthetase | 0.0054 | 0.0117 | 0.1587 |
Plasmodium vivax | arginyl-tRNA synthetase, putative | 0.0031 | 0.0026 | 0.0367 |
Brugia malayi | protein ZK524.3 | 0.0083 | 0.0233 | 0.1596 |
Brugia malayi | AMP-binding enzyme family protein | 0.0028 | 0.0015 | 0.0036 |
Plasmodium falciparum | threonine--tRNA ligase | 0.0054 | 0.0117 | 0.1896 |
Mycobacterium ulcerans | threonyl-tRNA synthetase | 0.0054 | 0.0117 | 0.0102 |
Mycobacterium tuberculosis | Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) | 0.0028 | 0.0015 | 0.0015 |
Loa Loa (eye worm) | bifunctional aminoacyl-tRNA synthetase | 0.021 | 0.073 | 0.5423 |
Mycobacterium tuberculosis | Peptide synthetase MbtE (peptide synthase) | 0.006 | 0.0139 | 0.0139 |
Entamoeba histolytica | isoleucyl-tRNA synthetase, putative | 0.0177 | 0.0601 | 0.4212 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0015 | 0.0084 |
Echinococcus granulosus | leucyl tRNA synthetase | 0.0063 | 0.0152 | 0.0927 |
Trichomonas vaginalis | conserved hypothetical protein | 0.003 | 0.0024 | 0.0336 |
Onchocerca volvulus | 0.0037 | 0.005 | 0.0802 | |
Mycobacterium tuberculosis | Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0028 | 0.0015 | 0.0015 |
Echinococcus granulosus | methionine tRNA synthetase | 0.0058 | 0.0135 | 0.0808 |
Plasmodium falciparum | valine--tRNA ligase, putative | 0.0063 | 0.0152 | 0.248 |
Schistosoma mansoni | glycyl-tRNA synthetase | 0.0223 | 0.0782 | 0.5227 |
Trypanosoma cruzi | long-chain-fatty-acid-CoA ligase, putative | 0.0028 | 0.0015 | 0.0188 |
Mycobacterium leprae | PROBABLE VALYL-tRNA SYNTHASE PROTEIN VALS (VALYL-tRNA SYNTHETASE) (VALINE--tRNA LIGASE) (VALINE TRANSLASE) ELONGS TO CLASS-I AMI | 0.0063 | 0.0152 | 0.0137 |
Wolbachia endosymbiont of Brugia malayi | formamidopyrimidine-DNA glycosylase | 0.0104 | 0.0313 | 0.4998 |
Leishmania major | methionyl-tRNA synthetase, putative | 0.0058 | 0.0135 | 0.2104 |
Trichomonas vaginalis | methionine-tRNA synthetase, putative | 0.0058 | 0.0135 | 0.2186 |
Echinococcus multilocularis | arginyl tRNA synthetase, cytoplasmic | 0.0031 | 0.0026 | 0.0073 |
Trypanosoma cruzi | threonyl-tRNA synthetase, putative | 0.0061 | 0.0146 | 0.2373 |
Echinococcus multilocularis | isoleucyl tRNA synthetase, cytoplasmic | 0.0177 | 0.0601 | 0.3967 |
Brugia malayi | glycyl-tRNA synthetase | 0.0223 | 0.0782 | 0.5527 |
Loa Loa (eye worm) | threonyl-tRNA synthetase | 0.0061 | 0.0146 | 0.1057 |
Entamoeba histolytica | valyl-tRNA synthetase, putative | 0.0063 | 0.0152 | 0.0984 |
Toxoplasma gondii | histone arginine methyltransferase PRMT5 | 0.0074 | 0.0196 | 0.0192 |
Trichomonas vaginalis | shk1 kinase-binding protein, putative | 0.0047 | 0.0091 | 0.1464 |
Trichomonas vaginalis | threonyl-tRNA synthetase, putative | 0.0054 | 0.0117 | 0.1896 |
Loa Loa (eye worm) | Skb1 methyltransferase | 0.0074 | 0.0196 | 0.1431 |
Schistosoma mansoni | acetyl-CoA synthetase | 0.0028 | 0.0015 | 0.0075 |
Toxoplasma gondii | methionyl-tRNA synthetase | 0.0074 | 0.0197 | 0.0193 |
Trypanosoma brucei | leucyl-tRNA synthetase, putative | 0.0063 | 0.0152 | 0.2336 |
Mycobacterium tuberculosis | Methionyl-tRNA synthetase MetS (MetRS) (methionine--tRNA ligase) | 0.0058 | 0.0135 | 0.0135 |
Mycobacterium leprae | Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) | 0.0037 | 0.005 | 0.0035 |
Mycobacterium tuberculosis | Probable formamidopyrimidine-DNA glycosylase Fpg (FAPY-DNA glycosylase) | 0.0104 | 0.0313 | 0.0313 |
Chlamydia trachomatis | methionine--tRNA ligase | 0.0404 | 0.1492 | 1 |
Plasmodium falciparum | acetyl-CoA synthetase, putative | 0.0028 | 0.0015 | 0.0188 |
Brugia malayi | Skb1 methyltransferase family protein | 0.0074 | 0.0196 | 0.1329 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0015 | 0.0084 |
Wolbachia endosymbiont of Brugia malayi | valyl-tRNA synthetase | 0.0063 | 0.0152 | 0.2193 |
Schistosoma mansoni | valine-tRNA ligase | 0.0063 | 0.0152 | 0.0995 |
Trypanosoma cruzi | arginyl-tRNA synthetase, putative | 0.0031 | 0.0026 | 0.0367 |
Loa Loa (eye worm) | hypothetical protein | 0.0063 | 0.0152 | 0.1105 |
Loa Loa (eye worm) | glycyl-tRNA synthetase | 0.0223 | 0.0782 | 0.5804 |
Mycobacterium ulcerans | non-ribosomal peptide synthetase MbtF | 0.006 | 0.0139 | 0.0124 |
Trypanosoma cruzi | threonyl-tRNA synthetase, putative | 0.0061 | 0.0146 | 0.2373 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0054 | 0.037 |
Echinococcus multilocularis | methionyl tRNA synthetase, cytoplasmic | 0.0404 | 0.1492 | 1 |
Mycobacterium tuberculosis | Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) | 0.1223 | 0.4707 | 0.4707 |
Mycobacterium ulcerans | phenyloxazoline synthase MbtB | 0.0433 | 0.1604 | 0.1591 |
Mycobacterium ulcerans | bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ACP synthetase | 0.1709 | 0.6613 | 0.6607 |
Entamoeba histolytica | arginyl-tRNA synthetase | 0.0031 | 0.0026 | 0.0077 |
Toxoplasma gondii | AMP-binding enzyme domain-containing protein | 0.0028 | 0.0015 | 0.0011 |
Echinococcus granulosus | arginyl tRNA synthetase cytoplasmic | 0.0031 | 0.0026 | 0.0073 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Transacetylation rate (binding) | = 0.02 nM/mg*min | Inhibition of AHAT-catalyzed transacylation of 4-aminoazobenzene | ChEMBL. | 6644748 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.