Detailed information for compound 75374

Basic information

Technical information
  • TDR Targets ID: 75374
  • Name: 2-[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl sulfanyl]-1H-benzimidazole
  • MW: 299.391 | Formula: C16H17N3OS
  • H donors: 1 H acceptors: 2 LogP: 3.49 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: COc1c(C)cnc(c1C)CSc1nc2c([nH]1)cccc2
  • InChi: 1S/C16H17N3OS/c1-10-8-17-14(11(2)15(10)20-3)9-21-16-18-12-6-4-5-7-13(12)19-16/h4-8H,9H2,1-3H3,(H,18,19)
  • InChiKey: VTVRIUZRAIVZSC-UHFFFAOYSA-N  

Network

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Synonyms

  • 2-[(4-methoxy-3,5-dimethyl-2-pyridyl)methylsulfanyl]-1H-benzimidazole
  • 2-[(4-methoxy-3,5-dimethyl-2-pyridyl)methylthio]-1H-benzimidazole
  • 2-[(4-methoxy-3,5-dimethyl-pyridin-2-yl)methylsulfanyl]-1H-benzimidazole

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity

Obtained from network model

Ranking Plot


Putative Targets List


Species Potential target Raw Global Species
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0034 0.01 0.0236
Echinococcus granulosus cathepsin L 0.004 0.0131 0.0308
Schistosoma mansoni calcium-transporting atpase sarcoplasmic/endoplasmic reticulum type (calcium pump) 0.0102 0.0446 0.1051
Brugia malayi MH1 domain containing protein 0.0025 0.0052 0.0215
Trypanosoma brucei PAB1-binding protein , putative 0.0051 0.0187 0.2468
Schistosoma mansoni calcium-transporting atpase sarcoplasmic/endoplasmic reticulum type (calcium pump) 0.0102 0.0446 0.1051
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0056 0.0212 0.1881
Echinococcus granulosus Ribosomal protein S6 kinase beta 2 0.0095 0.041 0.0966
Trypanosoma brucei DNA polymerase kappa, putative 0.0083 0.0349 0.4636
Echinococcus multilocularis tar DNA binding protein 0.0063 0.0248 0.0584
Loa Loa (eye worm) hypothetical protein 0.0231 0.1102 0.4928
Toxoplasma gondii P-type ATPase PMA1 0.0053 0.0198 0.0674
Brugia malayi Papain family cysteine protease containing protein 0.0018 0.002 0.0075
Trypanosoma cruzi copper-transporting ATPase-like protein, putative 0.0026 0.0062 0.009
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0049 0.0177 0.0266
Loa Loa (eye worm) sodium/potassium-transporting ATPase subunit alpha 0.0057 0.0216 0.0967
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0052 0.0192 0.2541
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0019 0.0023 0.0053
Plasmodium vivax thioredoxin reductase, putative 0.0141 0.0647 0.9054
Echinococcus multilocularis cathepsin L cysteine protease 0.0056 0.0212 0.0499
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0016 0.0007 0.0017
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0067 0.0267 0.1195
Brugia malayi Variant SH3 domain containing protein 0.0067 0.0267 0.1145
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0151 0.0694 0.1633
Trypanosoma cruzi cysteine peptidase, putative 0.0056 0.0212 0.032
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0018 0.002 0.0048
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.0018 0.002 0.0232
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0067 0.0269 0.0633
Schistosoma mansoni hypothetical protein 0.0034 0.01 0.0235
Brugia malayi cathepsin L-like cysteine proteinase 0.0018 0.002 0.0075
Mycobacterium ulcerans cation-transporter p-type ATPase B CtpB 0.0026 0.0062 0.0055
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0062 0.053
Loa Loa (eye worm) AGC/PKN protein kinase 0.0095 0.041 0.1835
Trypanosoma brucei hypothetical protein, conserved 0.0023 0.0044 0.0557
Leishmania major cathepsin L-like protease 0.0148 0.0682 0.9102
Schistosoma mansoni chromobox protein 0.0034 0.01 0.0236
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0323 0.1568 0.2165
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0015 0.0003 0.0007
Echinococcus multilocularis protein kinase c iota type 0.0162 0.075 0.1765
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0062 0.053
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.004 0.0133 0.1169
Trypanosoma cruzi cruzipain precursor, putative 0.0148 0.0682 0.1039
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0034 0.01 0.0319
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0036 0.0108 0.0948
Loa Loa (eye worm) fibroinase 0.0056 0.0212 0.0948
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0034 0.01 0.0236
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.004 0.0131 0.1151
Onchocerca volvulus 0.0028 0.0071 0.0465
Mycobacterium leprae PROBABLE CATION-TRANSPORTER P-TYPE ATPASE B CTPB 0.0026 0.0062 0.0024
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0049 0.0413
Loa Loa (eye worm) hypothetical protein 0.0029 0.0076 0.034
Loa Loa (eye worm) hypothetical protein 0.0018 0.002 0.009
Echinococcus granulosus geranylgeranyl transferase type 2 subunit alpha 0.004 0.0131 0.0308
Brugia malayi cathepsin L-like precursor 0.0034 0.0101 0.0426
Brugia malayi Thioredoxin reductase 0.0141 0.0647 0.2788
Echinococcus multilocularis neutral alpha glucosidase AB 0.0036 0.0108 0.0255
Schistosoma mansoni ap endonuclease 0.0019 0.0022 0.0052
Loa Loa (eye worm) prenyltransferase and squalene oxidase repeat family protein 0.0029 0.0076 0.034
Entamoeba histolytica cysteine protease, putative 0.004 0.0131 0.1418
Trypanosoma brucei copper-transporting ATPase-like protein, putative 0.0026 0.0062 0.0789
Loa Loa (eye worm) AGC/PKC/ALPHA protein kinase 0.0402 0.1972 0.8818
Echinococcus granulosus geranylgeranyl transferase type I beta subunit 0.0192 0.0905 0.213
Trichomonas vaginalis conserved hypothetical protein 0.0089 0.0381 0.3403
Trypanosoma brucei hypothetical protein, conserved 0.0034 0.0102 0.1333
Echinococcus granulosus cathepsin b 0.0018 0.002 0.0048
Loa Loa (eye worm) AGC/RSK/MSK protein kinase 0.0095 0.041 0.1835
Trichomonas vaginalis chromobox protein, putative 0.0034 0.01 0.0877
Loa Loa (eye worm) blistered cuticle protein 3 0.0026 0.006 0.0267
Plasmodium vivax glutathione reductase, putative 0.0141 0.0647 0.9054
Echinococcus granulosus plasma membrane calcium transporting ATPase 0.0077 0.0319 0.0751
Plasmodium vivax prenyltransferase alpha subunit, putative 0.0154 0.0712 1
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0034 0.0102 0.0326
Brugia malayi Ras association domain family 1 isoform A 0.0067 0.0267 0.1145
Plasmodium falciparum copper-transporting ATPase 0.0026 0.0062 0.06
Echinococcus granulosus cysteine protease 0.004 0.0131 0.0308
Echinococcus granulosus histone lysine methyltransferase setb 0.003 0.008 0.0188
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.004 0.0133 0.1169
Echinococcus granulosus protein kinase c eta type 0.0067 0.0267 0.0629
Mycobacterium tuberculosis Probable metal cation transporter ATPase P-type CtpE 0.0026 0.0062 0.0056
Plasmodium vivax protein prenyltransferase alpha subunit, putative 0.004 0.0131 0.1601
Loa Loa (eye worm) hypothetical protein 0.0082 0.0343 0.1534
Entamoeba histolytica cysteine protease, putative 0.004 0.0131 0.1418
Loa Loa (eye worm) hypothetical protein 0.0062 0.0243 0.1085
Echinococcus multilocularis chromobox protein 2 0.0034 0.01 0.0236
Trypanosoma cruzi calcium-transporting ATPase, putative 0.004 0.0131 0.0197
Loa Loa (eye worm) hypothetical protein 0.0016 0.0007 0.0033
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0049 0.0413
Brugia malayi Papain family cysteine protease containing protein 0.0018 0.002 0.0075
Brugia malayi Animal haem peroxidase family protein 0.0026 0.006 0.0247
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0056 0.0212 0.2772
Echinococcus multilocularis dnaJ subfamily B 0.0402 0.1971 0.4639
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0036 0.0111 0.0467
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0056 0.0212 0.1881
Loa Loa (eye worm) ctsf protein 0.0056 0.0212 0.0948
Loa Loa (eye worm) hypothetical protein 0.0026 0.006 0.0267
Echinococcus granulosus lysosomal alpha glucosidase 0.016 0.0741 0.1745
Brugia malayi Cathepsin L-like precursor 0.0034 0.0101 0.0426
Echinococcus multilocularis geranylgeranyl transferase type I beta subunit 0.0192 0.0905 0.213
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0052 0.0192 0.2541
Schistosoma mansoni tar DNA-binding protein 0.0063 0.0248 0.0584
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0044 0.0152 0.1654
Plasmodium vivax vivapain-2 0.0056 0.0212 0.2772
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0049 0.0177 0.017
Leishmania major cathepsin L-like protease 0.0056 0.0212 0.2802
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0061 0.0237 0.0559
Echinococcus granulosus myotubularin protein 13 0.0067 0.0267 0.0629
Trypanosoma brucei calcium-transporting ATPase, putative 0.004 0.0131 0.1723
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0024 0.0051 0.0073
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0018 0.002 0.0156
Giardia lamblia Rab geranylgeranyltransferase 0.004 0.0131 0.1601
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0018 0.002 0.0048
Trichomonas vaginalis DNA helicase recq, putative 0.0024 0.0051 0.043
Echinococcus granulosus tumor protein p63 0.0332 0.1616 0.3803
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0044 0.0152 0.1654
Schistosoma mansoni hypothetical protein 0.0402 0.1971 0.4639
Schistosoma mansoni calcium-transporting atpase 2 (atpase 2) 0.0102 0.0446 0.1051
Schistosoma mansoni multiple ankyrin repeats single kh domain protein 0.0088 0.0377 0.0886
Echinococcus multilocularis calcium transporting atpase 0.0102 0.0446 0.1051
Schistosoma mansoni lamin 0.0026 0.0062 0.0147
Loa Loa (eye worm) hypothetical protein 0.0119 0.0531 0.2377
Echinococcus granulosus Protein patched homolog 1 0.0042 0.0139 0.0326
Brugia malayi Pre-SET motif family protein 0.003 0.008 0.0333
Schistosoma mansoni hypothetical protein 0.004 0.0131 0.0308
Echinococcus granulosus nuclear factor of activated T cells 5 0.0072 0.0295 0.0695
Schistosoma mansoni DNA polymerase eta 0.0162 0.0749 0.1763
Onchocerca volvulus 0.0079 0.033 0.283
Echinococcus multilocularis lipoxygenase domain containing protein 0.0019 0.0026 0.0061
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0052 0.0192 0.2541
Echinococcus multilocularis neuropeptide s receptor 0.0461 0.2269 0.5342
Echinococcus granulosus thioredoxin glutathione reductase 0.0141 0.0647 0.1522
Schistosoma mansoni peroxidasin 0.0026 0.006 0.0141
Giardia lamblia Sgs1 DNA helicase, putative 0.0019 0.0023 0.0036
Trichomonas vaginalis conserved hypothetical protein 0.0089 0.0381 0.3403
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0049 0.0177 0.017
Mycobacterium tuberculosis Probable cation transporter P-type ATPase D CtpD 0.0026 0.0062 0.0056
Loa Loa (eye worm) RecQ helicase 0.0045 0.0158 0.0707
Onchocerca volvulus 0.0056 0.0212 0.1752
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0148 0.0682 0.9102
Treponema pallidum exodeoxyribonuclease (exoA) 0.0019 0.0022 0.0009
Trypanosoma brucei DNA polymerase kappa, putative 0.0137 0.0623 0.8317
Echinococcus granulosus mitogen activated protein kinase 3 0.0052 0.0192 0.0453
Loa Loa (eye worm) hypothetical protein 0.0022 0.0038 0.0171
Plasmodium falciparum calcium-transporting ATPase 0.0102 0.0446 0.6163
Treponema pallidum 4'-phosphopantetheinyl transferase 0.0023 0.0044 0.0032
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.0018 0.002 0.0048
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0047 0.0169 0.0718
Loa Loa (eye worm) prenyltransferase and squalene oxidase repeat family protein 0.0192 0.0905 0.4046
Brugia malayi cathepsin B-like cysteine proteinase 0.0018 0.002 0.0075
Brugia malayi haloacid dehalogenase-like hydrolase family protein 0.0047 0.0167 0.0711
Brugia malayi fibroinase precursor 0.0018 0.002 0.0075
Brugia malayi Sodium/potassium-transporting ATPase alpha-3 chain, putative 0.0037 0.0113 0.0478
Trichomonas vaginalis MYB3r3, putative 0.0086 0.0365 0.3263
Echinococcus multilocularis raf serine:threonine protein kinase 0.0067 0.0267 0.0629
Brugia malayi Probable protein farnesyltransferase beta subunit, putative 0.0029 0.0076 0.0317
Echinococcus granulosus Niemann Pick C1 protein 0.0138 0.063 0.1484
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0235 0.112 0.501
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0036 0.0108 0.0948
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0111 0.0491 0.2194
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0019 0.0022 0.0256
Trichomonas vaginalis AGC family protein kinase 0.0095 0.041 0.3666
Leishmania major vacuolar-type Ca2 -ATPase, putative 0.0094 0.0404 0.5375
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.003 0.008 0.0188
Trypanosoma brucei vacuolar-type Ca2+-ATPase, putative 0.0094 0.0404 0.5375
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0019 0.0023 0.0037
Loa Loa (eye worm) hypothetical protein 0.0026 0.006 0.0267
Echinococcus multilocularis protein dispatched 1 0.0047 0.0168 0.0397
Loa Loa (eye worm) hypothetical protein 0.012 0.054 0.2413
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0052 0.0192 0.029
Echinococcus granulosus intermediate filament protein 0.0026 0.0062 0.0147
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0016 0.0007 0.0017
Loa Loa (eye worm) hypothetical protein 0.0026 0.0062 0.0279
Schistosoma mansoni lipoxygenase 0.0019 0.0026 0.0061
Loa Loa (eye worm) hypothetical protein 0.0136 0.0619 0.277
Echinococcus granulosus L aminoadipate semialdehyde 0.0082 0.0343 0.0807
Mycobacterium ulcerans metal cation transporter p-type ATPase a 0.0084 0.0353 0.0346
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0022 0.0025
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0035 0.0106 0.1387
Brugia malayi ImpB/MucB/SamB family protein 0.0111 0.0491 0.2113
Trichomonas vaginalis Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase 0.0018 0.002 0.0156
Toxoplasma gondii AGC kinase 0.0095 0.041 0.1444
Schistosoma mansoni rac gtpase activating protein 0.0067 0.0267 0.0629
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0049 0.0177 0.0266
Schistosoma mansoni hypothetical protein 0.0034 0.01 0.0236
Plasmodium vivax hypothetical protein, conserved 0.0034 0.01 0.1158
Brugia malayi Prenyltransferase and squalene oxidase repeat family protein 0.0192 0.0905 0.3907
Echinococcus multilocularis phospholipid transporting ATPase IIB 0.0026 0.0062 0.0145
Toxoplasma gondii exonuclease III APE 0.0019 0.0022 0.0034
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.01 0.0877
Entamoeba histolytica myb-like DNA-binding domain containing protein 0.0086 0.0365 0.4021
Schistosoma mansoni cathepsin S (C01 family) 0.0018 0.002 0.0048
Echinococcus multilocularis phosphoserine phosphatase 0.0017 0.0012 0.0029
Echinococcus multilocularis plasma membrane calcium transporting ATPase 0.0077 0.0319 0.0751
Trichomonas vaginalis chromobox protein, putative 0.0095 0.0411 0.3674
Onchocerca volvulus 0.0019 0.0026 0.0054
Schistosoma mansoni cation-transporting atpase worm 0.0026 0.0062 0.0145
Trichomonas vaginalis AGC family protein kinase 0.0095 0.041 0.3666
Echinococcus granulosus neuropeptide receptor A26 0.0461 0.2269 0.5342
Trichomonas vaginalis cation-transporting ATPase, putative 0.0119 0.0531 0.4756
Trypanosoma brucei rac serine-threonine kinase, putative 0.0095 0.041 0.546
Trichomonas vaginalis ATPase, class I, type 8B, putative 0.0026 0.0062 0.053
Trypanosoma cruzi cysteine peptidase, putative 0.1301 0.6541 1
Brugia malayi Calcium-transporting ATPase sarcoplasmic/endoplasmic reticulum type 0.0102 0.0446 0.1922
Schistosoma mansoni serine/threonine protein kinase 0.0174 0.0813 0.1913
Echinococcus multilocularis phosphoserine phosphatase 0.0017 0.0012 0.0029
Trichomonas vaginalis geranylgeranyl transferase type I beta subunit, putative 0.0192 0.0905 0.8116
Trypanosoma brucei DNA polymerase kappa, putative 0.0137 0.0623 0.8317
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.004 0.0133 0.1169
Schistosoma mansoni hypothetical protein 0.0067 0.0267 0.0629
Giardia lamblia Kinase, CMGC MAPK 0.0052 0.0192 0.2491
Echinococcus multilocularis protein prenyltransferase alpha subunit 0.004 0.0131 0.0308
Trypanosoma brucei hypothetical protein, conserved 0.0034 0.0102 0.1333
Plasmodium falciparum geranylgeranyl transferase type2 beta subunit, putative 0.0029 0.0076 0.0807
Loa Loa (eye worm) hypothetical protein 0.0136 0.0619 0.277
Entamoeba histolytica cysteine proteinase, putative 0.004 0.0131 0.1418
Trypanosoma cruzi copper-transporting ATPase-like protein, putative 0.0026 0.0062 0.009
Plasmodium vivax geranylgeranyltransferase, putative 0.0029 0.0076 0.0807
Echinococcus granulosus chromobox protein 1 0.015 0.0692 0.1629
Echinococcus multilocularis neuropeptide receptor A26 0.0461 0.2269 0.5342
Echinococcus multilocularis protein farnesyltransferase alpha subunit 0.0154 0.0712 0.1676
Schistosoma mansoni protein kinase C mu 0.0069 0.028 0.0659
Schistosoma mansoni hypothetical protein 0.0016 0.0007 0.0017
Schistosoma mansoni cation-transporting atpase worm 0.0026 0.0062 0.0145
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0018 0.002 0.0156
Entamoeba histolytica cysteine protease, putative 0.004 0.0131 0.1418
Echinococcus granulosus Ankyrin repeat domain containing protein 0.0088 0.0377 0.0886
Trypanosoma cruzi Protein prenyltransferase alpha subunit repeat, putative 0.004 0.0131 0.0196
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0056 0.0212 0.0948
Trichomonas vaginalis r2r3-MYB transcription factor, putative 0.0086 0.0365 0.3263
Brugia malayi Smad1 0.0025 0.0052 0.0215
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0018 0.002 0.0048
Echinococcus multilocularis L aminoadipate semialdehyde 0.0082 0.0343 0.0807
Loa Loa (eye worm) hypothetical protein 0.0061 0.0235 0.1052
Echinococcus granulosus neutral alpha glucosidase AB 0.0036 0.0108 0.0255
Echinococcus granulosus unc 13 munc13 0.0079 0.033 0.0776
Leishmania major cathepsin L-like protease 0.0056 0.0212 0.2802
Echinococcus multilocularis Tetracycline resistance leader peptide, TetL 0.0094 0.0404 0.0951
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0018 0.002 0.0048
Loa Loa (eye worm) RNA binding protein 0.0063 0.0248 0.111
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0049 0.0177 0.2263
Entamoeba histolytica hypothetical protein 0.0034 0.01 0.108
Echinococcus multilocularis sterol regulatory element binding protein 0.0042 0.0139 0.0326
Entamoeba histolytica geranylgeranyl transferase beta subunit 0.0192 0.0905 1
Echinococcus multilocularis cysteine protease 0.0056 0.0212 0.0499
Trichomonas vaginalis AGC family protein kinase 0.0095 0.041 0.3666
Schistosoma mansoni hypothetical protein 0.0023 0.0044 0.0103
Schistosoma mansoni serine/threonine protein kinase 0.0095 0.041 0.0966
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.002 0.0156
Echinococcus multilocularis chromobox protein 1 0.015 0.0692 0.1629
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0127 0.0571 0.087
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0049 0.0413
Echinococcus granulosus chromodomain helicase DNA binding protein 1 0.0034 0.01 0.0236
Trypanosoma cruzi copper-transporting ATPase-like protein, putative 0.0017 0.0012 0.0015
Echinococcus granulosus protein farnesyltransferase alpha subunit 0.0154 0.0712 0.1676
Toxoplasma gondii prenyltransferase and squalene oxidase repeat-containing protein 0.0029 0.0076 0.0231
Echinococcus granulosus phospholipid transporting ATPase VA 0.0017 0.0012 0.0029
Entamoeba histolytica hypothetical protein 0.0144 0.066 0.7283
Brugia malayi Animal haem peroxidase family protein 0.0026 0.006 0.0247
Trichomonas vaginalis conserved hypothetical protein 0.0037 0.0118 0.1034
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0148 0.0682 0.9102
Brugia malayi Papain family cysteine protease containing protein 0.0056 0.0212 0.0906
Echinococcus granulosus neuropeptide s receptor 0.0461 0.2269 0.5342
Trichomonas vaginalis alpha-galactosidase/alpha-N-acetylgalactosaminidase, putative 0.0067 0.0269 0.2393
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.0094 0.0404 0.3609
Echinococcus granulosus raf serine:threonine protein kinase 0.0067 0.0267 0.0629
Entamoeba histolytica Plasma membrane calcium-transporting ATPase, putative 0.0094 0.0404 0.4447
Leishmania major P-type H -ATPase, putative 0.0053 0.0198 0.2616
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0098 0.0427 0.1005
Schistosoma mansoni microtubule-associated protein tau 0.0678 0.3375 0.7944
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0095 0.0825
Brugia malayi diacylglycerol kinase 0.0067 0.0267 0.1145
Mycobacterium leprae Probable metal cation-transporting P-type ATPase C CtpC 0.0026 0.0062 0.0024
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0018 0.002 0.0156
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0108 0.0948
Echinococcus multilocularis Na+:K+ ATPase alpha subunit 0.0067 0.0268 0.063
Loa Loa (eye worm) hypothetical protein 0.0042 0.0139 0.062
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0148 0.0682 0.9102
Schistosoma mansoni Smad4 0.0025 0.0052 0.0123
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0054 0.0203 0.0479
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.004 0.0131 0.1715
Echinococcus multilocularis musashi 0.0026 0.0062 0.0147
Loa Loa (eye worm) hypothetical protein 0.0019 0.0026 0.0117
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0034 0.01 0.0877
Plasmodium vivax multidomain scavenger receptor, putative 0.0019 0.0026 0.0085
Brugia malayi Cathepsin L-like precursor 0.0056 0.0212 0.0906
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0097 0.0419 0.4619
Loa Loa (eye worm) phosphatidylinositol 3 0.0015 0.0003 0.0013
Loa Loa (eye worm) latrophilin receptor protein 2 0.0016 0.0007 0.0033
Plasmodium falciparum ataxin-2 like protein, putative 0.0051 0.0187 0.2412
Schistosoma mansoni cation-transporting atpase 13a1 (G-box binding protein) 0.0026 0.0062 0.0145
Echinococcus multilocularis unc 13 (munc13) 0.0079 0.033 0.0776
Trypanosoma cruzi proton motive ATPase 1, putative 0.0017 0.0012 0.0015
Schistosoma mansoni geranylgeranyl transferase type I beta subunit 0.0192 0.0905 0.213
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0018 0.002 0.0156
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0018 0.002 0.009
Echinococcus multilocularis Ca2+ transporting ATPase plasma membrane 0.0077 0.0319 0.0751
Trypanosoma cruzi trypanothione reductase, putative 0.0049 0.0177 0.0266
Loa Loa (eye worm) hypothetical protein 0.0067 0.0267 0.1195
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0101 0.0439 0.1034
Entamoeba histolytica Plasma membrane calcium-transporting ATPase, putative 0.0094 0.0404 0.4447
Brugia malayi RNA binding protein 0.0063 0.0248 0.1062
Loa Loa (eye worm) thioredoxin reductase 0.0141 0.0647 0.2892
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0056 0.0212 0.1881
Loa Loa (eye worm) cytochrome P450 family protein 0.0016 0.0007 0.003
Echinococcus granulosus lamin 0.0026 0.0062 0.0147
Treponema pallidum NADH oxidase 0.0049 0.0177 0.0164
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0056 0.0212 0.1881
Brugia malayi Calcitonin receptor-like protein seb-1 0.005 0.018 0.0767
Toxoplasma gondii cathepsin CPC1 0.0018 0.002 0.0028
Echinococcus multilocularis mitogen activated protein kinase 3 0.0052 0.0192 0.0453
Mycobacterium tuberculosis Probable oxidoreductase 0.0359 0.1751 0.2422
Entamoeba histolytica cysteine protease, putative 0.004 0.0131 0.1418
Loa Loa (eye worm) hypothetical protein 0.0203 0.0959 0.4289
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0019 0.0023 0.0053
Echinococcus granulosus copper transporting ATPase 1 0.0026 0.0062 0.0145
Entamoeba histolytica calcium-transporting P-type ATPase, putative 0.0084 0.0353 0.3878
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0095 0.0825
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0018 0.002 0.0048
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.0067 0.0267 0.0629
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0044 0.0152 0.0358
Schistosoma mansoni ap endonuclease 0.0019 0.0022 0.0052
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0205 0.097 0.434
Echinococcus granulosus protein kinase C gamma type 0.0494 0.2442 0.5747
Entamoeba histolytica cysteine protease, putative 0.004 0.0131 0.1418
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.0077 0.0319 0.2846
Mycobacterium ulcerans DNA polymerase IV 0.0137 0.0623 0.0617
Brugia malayi Protein prenyltransferase alpha subunit repeat containing protein 0.004 0.0131 0.0555
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0052 0.0192 0.0861
Echinococcus multilocularis bloom syndrome protein 0.0045 0.0158 0.0372
Loa Loa (eye worm) hypothetical protein 0.0067 0.0267 0.1195
Echinococcus multilocularis chromobox protein 1 0.015 0.0692 0.1629
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0022 0.0038 0.0171
Plasmodium falciparum protein farnesyltransferase subunit alpha 0.0154 0.0712 1
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0019 0.0022 0.0015
Trypanosoma brucei P-type H+-ATPase, putative 0.0053 0.0198 0.2616
Loa Loa (eye worm) hypothetical protein 0.0026 0.006 0.0267
Loa Loa (eye worm) hypothetical protein 0.0051 0.0187 0.0837
Giardia lamblia Prenyltransferase 0.0029 0.0076 0.0807
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0034 0.01 0.108
Schistosoma mansoni chromobox protein 0.015 0.0692 0.1629
Brugia malayi Peroxidasin 0.0026 0.006 0.0247
Echinococcus granulosus lamin dm0 0.0026 0.0062 0.0147
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0044 0.0152 0.0358
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.004 0.0131 0.0196
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0015 0.0003 0.0007
Onchocerca volvulus 0.004 0.0131 0.1012
Brugia malayi potential phospholipid-transporting ATPase IIB, putative 0.0026 0.0062 0.0255
Entamoeba histolytica myb-like DNA-binding domain containing protein 0.0086 0.0365 0.4021
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0148 0.0682 0.9102
Trichomonas vaginalis sucrase-isomaltase, putative 0.0036 0.0108 0.0948
Schistosoma mansoni alpha-glucosidase 0.0138 0.0628 0.1479
Entamoeba histolytica plasma membrane calcium-transporting ATPase 1, putative 0.0057 0.0218 0.2389
Loa Loa (eye worm) hypothetical protein 0.0079 0.033 0.1475
Entamoeba histolytica protein farnesyltransferase alpha subunit, putative 0.0154 0.0712 0.7862
Echinococcus multilocularis serine:threonine protein kinase MRCK beta 0.0069 0.028 0.0659
Loa Loa (eye worm) cysteine protease 0.0056 0.0212 0.0948
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0036 0.0108 0.0484
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0056 0.0212 0.1881
Loa Loa (eye worm) hypothetical protein 0.0034 0.01 0.0449
Trichomonas vaginalis AGC family protein kinase 0.0095 0.041 0.3666
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.01 0.0877
Trypanosoma cruzi major cysteine proteinase, putative 0.0018 0.002 0.0027
Schistosoma mansoni cathepsin s 0.0022 0.0038 0.009
Loa Loa (eye worm) hypothetical protein 0.0454 0.2236 1
Echinococcus multilocularis calcium transporting ATPase type 2C member 0.0119 0.0531 0.1251
Schistosoma mansoni tar DNA-binding protein 0.0063 0.0248 0.0584
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0049 0.0177 0.233
Schistosoma mansoni diacylglycerol kinase theta 0.0067 0.0267 0.0629
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0148 0.0682 0.9102
Mycobacterium ulcerans DNA polymerase IV 0.0137 0.0623 0.0617
Schistosoma mansoni alpha glucosidase 0.0036 0.0108 0.0255
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0031 0.0083 0.0195
Giardia lamblia Rab geranylgeranyltransferase 0.0029 0.0076 0.0807
Echinococcus multilocularis chromodomain helicase DNA binding protein 1 0.0034 0.01 0.0236
Echinococcus multilocularis X box binding protein 1 0.0283 0.1367 0.3217
Trypanosoma cruzi plasma membrane Ca2+ ATPase 0.0094 0.0404 0.0613
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0117 0.0524 0.0703
Schistosoma mansoni unc-13 (munc13) 0.0079 0.033 0.0776
Toxoplasma gondii haloacid dehalogenase family hydrolase domain-containing protein 0.0026 0.0062 0.0179
Trypanosoma cruzi DNA polymerase eta, putative 0.0085 0.0361 0.0547
Schistosoma mansoni cpg binding protein 0.0028 0.0071 0.0167
Echinococcus multilocularis RNA directed DNA polymerase 0.0387 0.1896 0.4463
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.002 0.0156
Plasmodium vivax cation transporting ATPase, putative 0.0026 0.0062 0.06
Trypanosoma brucei DNA polymerase kappa, putative 0.0137 0.0623 0.8317
Trichomonas vaginalis hypothetical protein 0.0034 0.01 0.0877
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0016 0.0007 0.002
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0044 0.0152 0.0358
Onchocerca volvulus 0.0047 0.0169 0.1355
Echinococcus granulosus N chimaerin 0.0067 0.0267 0.0629
Plasmodium vivax vivapain-2 0.0056 0.0212 0.2772
Echinococcus multilocularis Smad4 0.0025 0.0052 0.0123
Echinococcus multilocularis cysteine protease 0.0056 0.0212 0.0499
Plasmodium vivax geranylgeranyl transferase type2 beta subunit, putative 0.0029 0.0076 0.0807
Schistosoma mansoni ATPase 0.0119 0.0531 0.1251
Mycobacterium tuberculosis Possible metal cation transporting P-type ATPase CtpH 0.0057 0.0216 0.0272
Loa Loa (eye worm) hypothetical protein 0.0047 0.0164 0.0736
Brugia malayi M-phase phosphoprotein, mpp8 0.0122 0.0549 0.2367
Schistosoma mansoni serine/threonine protein kinase 0.0069 0.028 0.0659
Loa Loa (eye worm) doublecortin family protein 0.0019 0.0026 0.0117
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0101 0.0439 0.1034
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.0094 0.0404 0.3609
Trichomonas vaginalis AGC family protein kinase 0.0095 0.041 0.3666
Loa Loa (eye worm) hypothetical protein 0.0026 0.006 0.0267
Toxoplasma gondii hypothetical protein 0.004 0.0131 0.043
Trichomonas vaginalis pc-MYB2, putative 0.0086 0.0365 0.3263
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.004 0.0133 0.1169
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0144 0.066 0.1553
Onchocerca volvulus 0.0056 0.0212 0.1752
Loa Loa (eye worm) hypothetical protein 0.0067 0.0267 0.1195
Loa Loa (eye worm) calcium ATPase 0.0057 0.0218 0.0977
Trypanosoma brucei DNA polymerase kappa, putative 0.0083 0.0349 0.4636
Trypanosoma cruzi hypothetical protein, conserved 0.004 0.0131 0.0196
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0056 0.0212 0.1881
Mycobacterium leprae PROBABLE UDP-N-ACETYLGLUCOSAMINE 1-CARBOXYVINYLTRANSFERASE MURA 0.1423 0.716 1
Entamoeba histolytica cysteine proteinase, putative 0.0056 0.0212 0.2318
Loa Loa (eye worm) cytochrome P450 family protein 0.0026 0.0058 0.0261
Entamoeba histolytica phospholipid-transporting P-type ATPase, putative 0.0026 0.0062 0.0652
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0056 0.0212 0.1881
Plasmodium falciparum geranylgeranyltransferase, putative 0.0029 0.0076 0.0807
Loa Loa (eye worm) E1-E2 ATPase 0.0053 0.0198 0.0886
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0034 0.01 0.108
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.006 0.0518
Leishmania major DNA polymerase kappa, putative 0.0117 0.0524 0.6978
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0052 0.0192 0.0654
Leishmania major vacuolar-type Ca2 -ATPase, putative 0.0094 0.0404 0.5375
Toxoplasma gondii Myb family DNA-binding domain-containing protein 0.0087 0.0368 0.1289
Brugia malayi Papain family cysteine protease containing protein 0.004 0.0131 0.0554
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0019 0.0023 0.0053
Plasmodium falciparum ataxin-2 like protein, putative 0.0051 0.0187 0.2412
Schistosoma mansoni hypothetical protein 0.0019 0.0026 0.0061
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0034 0.01 0.1158
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0049 0.0413
Onchocerca volvulus 0.0026 0.006 0.0362
Onchocerca volvulus 0.0026 0.0062 0.0385
Trichomonas vaginalis chromobox protein, putative 0.0095 0.0411 0.3674
Brugia malayi Cathepsin L-like cysteine proteinase 0.0034 0.0101 0.0426
Entamoeba histolytica hypothetical protein 0.0144 0.066 0.7283
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0101 0.0439 0.1034
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.004 0.0131 0.0308
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0117 0.0524 0.6978
Brugia malayi Cytochrome P450 family protein 0.0016 0.0007 0.0017
Trichomonas vaginalis DNA helicase recq, putative 0.0045 0.0158 0.1396
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0049 0.0177 0.0266
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0026 0.0062 0.0279
Chlamydia trachomatis metal transport ATPase 0.0026 0.0062 0.0017
Echinococcus multilocularis thioredoxin glutathione reductase 0.0141 0.0647 0.1522
Schistosoma mansoni serine/threonine kinase 0.0095 0.041 0.0966
Echinococcus multilocularis Alpha N acetylgalactosaminidase 0.0101 0.0439 0.1034
Entamoeba histolytica myb-like DNA-binding domain containing protein 0.0086 0.0365 0.4021
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0036 0.0108 0.1167
Schistosoma mansoni tar DNA-binding protein 0.0063 0.0248 0.0584
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0067 0.0269 0.0633
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0035 0.0106 0.1387
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0049 0.0177 0.2263
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0119 0.1047
Trichomonas vaginalis CMGC family protein kinase 0.0052 0.0192 0.1706
Schistosoma mansoni chromobox protein 0.0034 0.01 0.0236
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.004 0.0133 0.1169
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0056 0.0212 0.1881
Trypanosoma brucei DNA polymerase IV, putative 0.0137 0.0623 0.8317
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0108 0.0948
Echinococcus multilocularis Diacylglycerol kinase theta 0.0067 0.0267 0.0629
Trichomonas vaginalis r2r3-MYB transcription factor, putative 0.0086 0.0365 0.3263
Schistosoma mansoni chromobox protein 0.015 0.0692 0.1629
Loa Loa (eye worm) hypothetical protein 0.0026 0.006 0.0267
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.004 0.0133 0.1169
Loa Loa (eye worm) hypothetical protein 0.0139 0.0636 0.2843
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.002 0.0156
Echinococcus multilocularis lysosomal alpha glucosidase 0.016 0.0741 0.1745
Trichomonas vaginalis protein farnesyltransferase alpha subunit, putative 0.0154 0.0712 0.6381
Echinococcus multilocularis telomerase reverse transcriptase subunit 0.0387 0.1896 0.4463
Trypanosoma cruzi hypothetical protein, conserved 0.0034 0.0102 0.0152
Plasmodium vivax calcium-transporting ATPase, putative 0.0119 0.0531 0.739
Trichomonas vaginalis protein farnesyltransferase beta subunit, putative 0.0029 0.0076 0.0658
Echinococcus granulosus Rac GTPase activating protein 1 0.0067 0.0267 0.0629
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0359 0.1751 0.2422
Loa Loa (eye worm) hypothetical protein 0.0061 0.0238 0.1066
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.01 0.0877
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0106 0.0929
Toxoplasma gondii histone lysine methyltransferase SET1 0.0055 0.0205 0.0699
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.01 0.0877
Trypanosoma brucei DNA polymerase IV, putative 0.0137 0.0623 0.8317
Schistosoma mansoni cation-transporting ATPase 0.0026 0.0062 0.0145
Entamoeba histolytica protein kinase, putative 0.0095 0.041 0.4517
Loa Loa (eye worm) hypothetical protein 0.0051 0.0186 0.0832
Echinococcus multilocularis cpg binding protein 0.003 0.0079 0.0186
Schistosoma mansoni hypothetical protein 0.004 0.0131 0.0308
Loa Loa (eye worm) hypothetical protein 0.012 0.054 0.2413
Brugia malayi Animal haem peroxidase family protein 0.0026 0.006 0.0247
Brugia malayi Latrophilin receptor protein 2 0.0016 0.0007 0.002
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.004 0.013 0.1587
Brugia malayi chromobox protein homolog 3 0.0089 0.0381 0.1638
Entamoeba histolytica cysteine proteinase, putative 0.004 0.0131 0.1418
Trypanosoma brucei DNA polymerase kappa, putative 0.0137 0.0623 0.8317
Brugia malayi Cytochrome P450 family protein 0.0016 0.0007 0.0017
Loa Loa (eye worm) hypothetical protein 0.0018 0.002 0.009
Schistosoma mansoni tar DNA-binding protein 0.0063 0.0248 0.0584
Trichomonas vaginalis C-MYB, putative 0.0086 0.0365 0.3263
Plasmodium vivax vivapain-3 0.004 0.0131 0.1599
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0018 0.002 0.009
Loa Loa (eye worm) pigment dispersing factor receptor c 0.005 0.018 0.0804
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0024 0.0051 0.0641
Trypanosoma brucei calcium motive p-type ATPase, putative 0.0067 0.0268 0.355
Trypanosoma cruzi geranylgeranyl transferase type II beta subunit, putative 0.0029 0.0076 0.0112
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0049 0.0412
Leishmania major cysteine peptidase A (CPA) 0.0056 0.0212 0.2802
Brugia malayi Cathepsin L-like precursor 0.0056 0.0212 0.0906
Trypanosoma cruzi hypothetical protein, conserved 0.0029 0.0076 0.0112
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.0015 0.0005 0.0011
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.004 0.0133 0.1169
Mycobacterium ulcerans cation transporter p-type ATPase D CtpD 0.0026 0.0062 0.0055
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0049 0.0177 0.0155
Echinococcus multilocularis copper transporting ATPase 1 0.0026 0.0062 0.0145
Leishmania major cathepsin L-like protease 0.0148 0.0682 0.9102
Onchocerca volvulus 0.0056 0.0212 0.1752
Brugia malayi Cathepsin L-like precursor 0.0056 0.0212 0.0906
Trichomonas vaginalis chromobox protein, putative 0.015 0.0692 0.6201
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0082 0.0343 0.1473
Echinococcus multilocularis lysosomal alpha glucosidase 0.016 0.0741 0.1745
Trichomonas vaginalis phospholipid-transporting ATPase, putative 0.0026 0.0062 0.053
Brugia malayi diacylglycerol kinase 0.0067 0.0267 0.1145
Echinococcus granulosus Ca2 transporting ATPase plasma membrane 0.0077 0.0319 0.0751
Echinococcus multilocularis microtubule associated protein 2 0.0678 0.3375 0.7944
Loa Loa (eye worm) hypothetical protein 0.0097 0.0419 0.1876
Plasmodium vivax copper-transporting ATPase, putative 0.0026 0.0062 0.06
Brugia malayi p70 ribosomal S6 kinase beta 0.0095 0.041 0.1765
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.01 0.0877
Brugia malayi Blistered cuticle protein 3 0.0026 0.006 0.0247
Plasmodium vivax heterochromatin protein 1, putative 0.0034 0.01 0.1158
Onchocerca volvulus 0.0234 0.1115 1
Entamoeba histolytica cysteine protease, putative 0.0018 0.002 0.0192
Trypanosoma cruzi protein farnesyltransferase alpha subunit, putative 0.004 0.0131 0.0196
Trypanosoma brucei DNA polymerase eta, putative 0.0162 0.0749 1
Brugia malayi Glycosyl hydrolases family 31 protein 0.016 0.0741 0.32
Giardia lamblia Myb 1-like protein 0.0087 0.0368 0.5021
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0049 0.0177 0.0266
Echinococcus multilocularis phosphoserine phosphatase 0.0017 0.0012 0.0029
Brugia malayi hypothetical protein 0.012 0.0536 0.2308
Trichomonas vaginalis chromobox protein, putative 0.0034 0.01 0.0877
Entamoeba histolytica cysteine proteinase, putative 0.004 0.0131 0.1418
Trypanosoma cruzi cysteine proteinase, putative 0.004 0.0131 0.0196
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0022 0.0025
Trichomonas vaginalis r2r3-MYB transcription factor, putative 0.0086 0.0365 0.3263
Mycobacterium ulcerans metal cation-transporting p-type ATPase CtpC 0.0026 0.0062 0.0055
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0095 0.0825
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0069 0.028 0.1252
Echinococcus multilocularis Protein kinase C, brain isozyme 0.0561 0.2781 0.6546
Echinococcus granulosus protein farnesyltransferase subunit beta 0.0029 0.0076 0.0179
Entamoeba histolytica plasma membrane calcium ion-transporting ATPase, putative 0.0057 0.0218 0.2389
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0056 0.0212 0.1881
Entamoeba histolytica cation-transporting P-typeATPase, putative 0.0026 0.0062 0.0652
Entamoeba histolytica cysteine proteinase, putative 0.0034 0.0101 0.1091
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0056 0.0212 0.1881
Schistosoma mansoni geranylgeranyl transferase type II beta subunit 0.0029 0.0076 0.0179
Loa Loa (eye worm) hypothetical protein 0.0034 0.01 0.0449
Loa Loa (eye worm) hypothetical protein 0.0026 0.0062 0.0276
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0018 0.002 0.0192
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0323 0.1568 0.2165
Plasmodium vivax hypothetical protein, conserved 0.0034 0.01 0.1158
Echinococcus multilocularis serine threonine protein kinase 0.0494 0.2442 0.5747
Entamoeba histolytica Rab geranylgeranyltransferase beta subunit, putative 0.0029 0.0076 0.0811
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.0174 0.0813 0.3634
Leishmania major P-type H -ATPase, putative 0.0053 0.0198 0.2616
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.002 0.0156
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0148 0.0682 0.9102
Entamoeba histolytica cysteine proteinase, putative 0.0056 0.0212 0.2318
Giardia lamblia DNA damage repair protein 0.0034 0.0102 0.1187
Schistosoma mansoni hypothetical protein 0.0016 0.0007 0.0017
Mycobacterium ulcerans cation-transporter ATPase I CtpI 0.0057 0.0216 0.021
Brugia malayi hypothetical protein 0.0026 0.006 0.0247
Trypanosoma brucei lanosterol synthase 0.0029 0.0076 0.098
Leishmania major DNA damage repair protein, putative 0.0034 0.0102 0.1333
Trichomonas vaginalis chromobox protein, putative 0.015 0.0692 0.6201
Entamoeba histolytica Rab geranylgeranyltransferase alpha subunit, putative 0.004 0.0131 0.142
Trichomonas vaginalis PIKK family atypical protein kinase 0.0044 0.0152 0.1343
Schistosoma mansoni DNA helicase recq1 0.0019 0.0023 0.0053
Loa Loa (eye worm) glutathione reductase 0.0141 0.0647 0.2892
Trichomonas vaginalis conserved hypothetical protein 0.0055 0.0208 0.1849
Trichomonas vaginalis r2r3-MYB transcription factor, putative 0.0086 0.0365 0.3263
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0023 0.0044 0.0103
Mycobacterium ulcerans cation transporter p-type ATPase a CtpA 0.0026 0.0062 0.0055
Echinococcus granulosus NDR protein kinase 0.0095 0.041 0.0966
Echinococcus granulosus survival motor neuron protein 1 0.0232 0.1109 0.261
Mycobacterium tuberculosis Halimadienyl diphosphate synthase 0.0029 0.0076 0.0076
Plasmodium falciparum heterochromatin protein 1 0.0034 0.01 0.1158
Echinococcus multilocularis N chimaerin 0.0067 0.0267 0.0629
Entamoeba histolytica myb-like DNA-binding domain containing protein 0.0086 0.0365 0.4021
Schistosoma mansoni hypothetical protein 0.0016 0.0007 0.0017
Trichomonas vaginalis cation-transporting ATPase, putative 0.0094 0.0404 0.3609
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0049 0.0412
Schistosoma mansoni hypothetical protein 0.004 0.0131 0.0308
Toxoplasma gondii LsmAD domain-containing protein 0.0051 0.0187 0.0634
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.004 0.0133 0.1169
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.002 0.0156
Trypanosoma brucei protein farnesyltransferase beta subunit 0.0029 0.0076 0.098
Brugia malayi Protein kinase domain containing protein 0.0095 0.041 0.1765
Brugia malayi Heterochromatin protein 1 0.015 0.0692 0.2985
Onchocerca volvulus 0.0064 0.0253 0.2123
Brugia malayi ImpB/MucB/SamB family protein 0.0162 0.0749 0.3232
Trypanosoma cruzi target of rapamycin kinase 3 0.0035 0.0106 0.0158
Trypanosoma cruzi cysteine peptidase, putative 0.0148 0.0682 0.1039
Brugia malayi CHE-14 protein 0.0042 0.0139 0.0588
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0036 0.0108 0.0255
Leishmania major cathepsin L-like protease 0.0056 0.0212 0.2802
Trichomonas vaginalis r2r3-MYB transcription factor, putative 0.0087 0.0368 0.3282
Brugia malayi hypothetical protein 0.0019 0.0026 0.0101
Giardia lamblia GTOR 0.0044 0.0152 0.1907
Schistosoma mansoni DNA polymerase IV / kappa 0.0034 0.0102 0.0241
Trichomonas vaginalis serine/threonine-protein kinase sgk, putative 0.0092 0.0398 0.3552
Mycobacterium tuberculosis Conserved hypothetical protein 0.0111 0.0491 0.0657
Onchocerca volvulus 0.0019 0.0026 0.0054
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0034 0.01 0.0236
Brugia malayi Sodium/potassium-transporting ATPase alpha chain, putative 0.0057 0.0216 0.0925
Schistosoma mansoni cathepsin F (C01 family) 0.0056 0.0212 0.0499
Schistosoma mansoni serine/threonine protein kinase 0.0095 0.041 0.0966
Trichomonas vaginalis geranylgeranyl transferase type II beta subunit, putative 0.0029 0.0076 0.0658
Brugia malayi Papain family cysteine protease containing protein 0.0018 0.002 0.0075
Plasmodium falciparum thioredoxin reductase 0.0049 0.0177 0.2263
Loa Loa (eye worm) MH1 domain-containing protein 0.0025 0.0052 0.0234
Echinococcus multilocularis cation transporting ATPase 13A3 0.0026 0.0062 0.0145
Echinococcus granulosus bloom syndrome protein 0.0045 0.0158 0.0372
Echinococcus multilocularis smad 0.0025 0.0052 0.0123
Treponema pallidum cation-transporting ATPase, P-type 0.0026 0.0062 0.0049
Loa Loa (eye worm) intermediate filament protein 0.0026 0.0062 0.0279
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0044 0.0152 0.0646
Echinococcus multilocularis dna polymerase kappa 0.0137 0.0623 0.1467
Brugia malayi Doublecortin family protein 0.0019 0.0026 0.0101
Brugia malayi polk-prov protein 0.0061 0.0235 0.1006
Plasmodium falciparum geranylgeranyl transferase type-2 subunit alpha, putative 0.004 0.0131 0.1601
Brugia malayi TAR-binding protein 0.0063 0.0248 0.1062
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0049 0.0177 0.233
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0056 0.0212 0.1881
Onchocerca volvulus 0.0084 0.0353 0.3037
Schistosoma mansoni lamin 0.0026 0.0062 0.0147
Trypanosoma cruzi DNA damage repair protein, putative 0.0034 0.0102 0.0152
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0359 0.1751 0.2398
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0049 0.0177 0.0416
Trichomonas vaginalis r2r3-MYB transcription factor, putative 0.0086 0.0365 0.3263
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0023 0.0044 0.0116
Trypanosoma brucei geranylgeranyl transferase type II beta subunit, putative 0.0029 0.0076 0.098
Schistosoma mansoni intermediate filament proteins 0.0026 0.0062 0.0147
Trichomonas vaginalis cation-transporting ATPase, putative 0.0119 0.0531 0.4756
Brugia malayi Animal haem peroxidase family protein 0.0026 0.006 0.0247
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0108 0.0948
Trichomonas vaginalis C-MYB, putative 0.0086 0.0365 0.3263
Loa Loa (eye worm) CHromoDomain protein family member 0.0036 0.0108 0.0485
Trypanosoma cruzi lanosterol synthase, putative 0.0029 0.0076 0.0112
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0018 0.002 0.0192
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0095 0.0825
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0022 0.0172
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.0018 0.002 0.009
Loa Loa (eye worm) hypothetical protein 0.0067 0.0267 0.1195
Toxoplasma gondii cathepsin B 0.0018 0.002 0.0028
Onchocerca volvulus Cathepsin L homolog 0.0056 0.0212 0.1752
Echinococcus granulosus GPCR family 2 0.0016 0.0007 0.0017
Entamoeba histolytica phospholipid-transporting P-type ATPase, putative 0.0026 0.0062 0.0652
Echinococcus granulosus sterol regulatory element binding protein 0.0042 0.0139 0.0326
Echinococcus multilocularis mitogen activated protein kinase 0.0052 0.0192 0.0453
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0019 0.0023 0.0037
Echinococcus granulosus RNA directed DNA polymerase 0.0387 0.1896 0.4463
Onchocerca volvulus Peroxidase homolog 0.0026 0.006 0.0362
Brugia malayi Protein kinase c protein 2 0.0469 0.2311 1
Trichomonas vaginalis Clan CA, family C1, cathepsin F-like cysteine peptidase 0.0018 0.002 0.0156
Loa Loa (eye worm) CXXC zinc finger family protein 0.0028 0.0071 0.0318
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0108 0.0948
Brugia malayi cathepsin Z-like cysteine proteinase 0.0018 0.002 0.0075
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.002 0.0156
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0019 0.0023 0.0086
Loa Loa (eye worm) hypothetical protein 0.0026 0.0062 0.0276
Trypanosoma cruzi DNA polymerase kappa, putative 0.0137 0.0623 0.0949
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.002 0.0156
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0019 0.0022 0.0052
Trypanosoma cruzi DNA polymerase kappa, putative 0.0137 0.0623 0.0949
Trypanosoma brucei unspecified product 0.0076 0.0316 0.4195
Leishmania major proton motive ATPase, putative 0.0026 0.0062 0.0789
Schistosoma mansoni survival motor neuron protein 0.0047 0.0169 0.0397
Brugia malayi hypothetical protein 0.0017 0.0012 0.0042
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0042 0.0139 0.062
Schistosoma mansoni DNA helicase recq5 0.0019 0.0023 0.0053
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.004 0.0131 0.0308
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0095 0.0411 0.3572
Trypanosoma brucei DNA polymerase kappa, putative 0.0083 0.0349 0.4636
Schistosoma mansoni blooms syndrome DNA helicase 0.0036 0.0109 0.0258
Trypanosoma brucei trypanothione reductase 0.0141 0.0647 0.8627
Entamoeba histolytica cysteine protease, putative 0.004 0.0131 0.1418
Trichomonas vaginalis glutathione reductase, putative 0.0049 0.0177 0.1564
Schistosoma mansoni Na+/K+ transporting ATPase subunit alpha 0.0084 0.0353 0.083
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0056 0.0212 0.1881
Trichomonas vaginalis MYB, putative 0.0087 0.0368 0.3282
Loa Loa (eye worm) MH2 domain-containing protein 0.0025 0.0052 0.0234
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0054 0.0203 0.0479
Schistosoma mansoni tar DNA-binding protein 0.0063 0.0248 0.0584
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.004 0.0131 0.1151
Loa Loa (eye worm) hypothetical protein 0.0067 0.0267 0.1195
Leishmania major calcium-translocating P-type ATPase 0.0119 0.0531 0.7083
Mycobacterium leprae PROBABLE CATION-TRANSPORTER ATPASE I CTPI 0.0057 0.0216 0.0242
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0034 0.01 0.0877
Echinococcus granulosus expressed conserved protein 0.0091 0.039 0.0917
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0056 0.0212 0.0948
Entamoeba histolytica plasma membrane calcium ion-transporting ATPase, putative 0.0047 0.0164 0.1792
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0049 0.0412
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0323 0.1568 0.214
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0056 0.0212 0.2772
Trichomonas vaginalis type I geranylgeranyltransferase beta subunit, putative 0.0029 0.0076 0.0658
Mycobacterium leprae probable 3-phosphoshikimate 1-carboxyvinyl transferase AroA (5-ENOLPYRUVYLSHIKIMATE-3-PHOSPHATE SYNTHASE) (EPSP SYNTHASE) (EPSPS 0.0559 0.2767 0.3826
Brugia malayi RhoGAP domain containing protein 0.0067 0.0267 0.1145
Entamoeba histolytica cysteine protease, putative 0.0018 0.002 0.0192
Trichomonas vaginalis geranylgeranyl transferase type II beta subunit, putative 0.0029 0.0076 0.0658
Onchocerca volvulus Cathepsin L homolog 0.0056 0.0212 0.1752
Onchocerca volvulus 0.0082 0.0343 0.2949
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.008 0.0188
Schistosoma mansoni smad1 5 8 and 0.0025 0.0052 0.0123
Trypanosoma cruzi hypothetical protein, conserved 0.0029 0.0076 0.0112
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0073 0.0634
Leishmania major phosphopantetheinyl transferase-like protein 0.0023 0.0044 0.0557
Entamoeba histolytica hypothetical protein 0.0018 0.002 0.0192
Trypanosoma cruzi major cysteine proteinase, putative 0.0111 0.049 0.0746
Plasmodium falciparum non-SERCA-type Ca2+ -transporting P-ATPase 0.0119 0.0531 0.739
Schistosoma mansoni cathepsin B (C01 family) 0.0018 0.002 0.0048
Schistosoma mansoni na+/k+ atpase alpha subunit 0.0067 0.0268 0.063
Plasmodium vivax DNA repair protein REV1, putative 0.0034 0.0102 0.1187
Trypanosoma cruzi lanosterol synthase, putative 0.0029 0.0076 0.0112
Leishmania major hypothetical protein, conserved 0.0051 0.0187 0.2468
Trypanosoma cruzi calcium motive p-type ATPase, putative 0.0067 0.0268 0.0405
Brugia malayi Melibiase family protein 0.0067 0.0269 0.1152
Echinococcus multilocularis Glycoside hydrolase, family 27 0.0101 0.0439 0.1034
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0018 0.002 0.0027
Loa Loa (eye worm) hypothetical protein 0.0019 0.0026 0.0117
Schistosoma mansoni terminal deoxycytidyl transferase 0.0111 0.0491 0.1155
Trichomonas vaginalis cation-transporting ATPase, putative 0.0026 0.0062 0.053
Toxoplasma gondii sarco/endoplasmic reticulum Ca2+-ATPase 0.0119 0.0531 0.1884
Echinococcus multilocularis cathepsin L 0.004 0.0131 0.0308
Trypanosoma cruzi Calcium ATPase SERCA-like 0.0119 0.0531 0.0808
Giardia lamblia Rab geranylgeranyltransferase 0.0154 0.0712 1
Brugia malayi Type III restriction enzyme, res subunit family protein 0.0034 0.01 0.0422
Echinococcus granulosus lipoxygenase domain containing protein 0.0019 0.0026 0.0061
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0148 0.0682 0.9102
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.01 0.0877
Brugia malayi Probable calcium-transporting ATPase KIAA0703 0.0075 0.031 0.1331
Schistosoma mansoni vav2 0.0067 0.0267 0.0629
Schistosoma mansoni hypothetical protein 0.0144 0.066 0.1553
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0144 0.066 0.1553
Entamoeba histolytica protein kinase, putative 0.0095 0.041 0.4517
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0016 0.0007 0.0017
Echinococcus multilocularis tumor protein p63 0.0332 0.1616 0.3803
Entamoeba histolytica cysteine protease, putative 0.004 0.0131 0.1418
Onchocerca volvulus 0.0026 0.006 0.0362
Giardia lamblia Phospholipid-transporting ATPase IA, putative 0.0026 0.0062 0.06
Echinococcus multilocularis lamin 0.0026 0.0062 0.0147
Echinococcus granulosus Diacylglycerol kinase theta 0.0067 0.0267 0.0629
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0018 0.002 0.0048
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0064 0.0253 0.0595
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0101 0.0439 0.1034
Mycobacterium ulcerans UDP-N-acetylglucosamine 1-carboxyvinyltransferase 0.1981 1 1
Brugia malayi cahepsin L-like non-peptiedase homolog 0.0018 0.002 0.0075
Echinococcus granulosus cation transporting ATPase 13A3 0.0026 0.0062 0.0145
Leishmania major protein farnesyltransferase alpha subunit, putative 0.004 0.0131 0.1716
Loa Loa (eye worm) AGC/AKT protein kinase 0.0095 0.041 0.1835
Schistosoma mansoni ATPase 0.0119 0.0531 0.1251
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0137 0.0623 0.5585
Schistosoma mansoni smad1 5 8 and 0.0025 0.0052 0.0123
Schistosoma mansoni phosphoserine phosphatase 0.0017 0.0012 0.0029
Echinococcus multilocularis Rab geranylgeranyltransferase, beta subunit 0.0029 0.0076 0.0179
Loa Loa (eye worm) hypothetical protein 0.0084 0.0353 0.1577
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0019 0.0023 0.0086
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0141 0.0647 0.0875
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0018 0.002 0.0048
Entamoeba histolytica hypothetical protein 0.0144 0.066 0.7283
Giardia lamblia Plasma membrane calcium-transporting ATPase 2 0.0094 0.0404 0.5548
Loa Loa (eye worm) hypothetical protein 0.0154 0.0712 0.3184
Loa Loa (eye worm) hypothetical protein 0.0027 0.0064 0.0286
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0036 0.0108 0.0255
Echinococcus multilocularis protein kinase c epsilon type 0.0174 0.0813 0.1913
Loa Loa (eye worm) CYP4Cod1 0.0016 0.0007 0.003
Echinococcus multilocularis serine:threonine protein kinase 38 0.0095 0.041 0.0966
Schistosoma mansoni smad 0.0025 0.0052 0.0123
Brugia malayi Membrane calcium atpase protein 3 0.0077 0.0319 0.137
Loa Loa (eye worm) hypothetical protein 0.0067 0.0267 0.1195
Brugia malayi calcium ATPase 0.004 0.0133 0.0566
Echinococcus multilocularis ribosomal protein s6 kinase beta 1 0.0095 0.041 0.0966
Plasmodium vivax P-type ATPase4, putative 0.0119 0.0531 0.739
Trichomonas vaginalis AGC family protein kinase 0.0095 0.041 0.3666
Trichomonas vaginalis protein farnesyltransferase alpha subunit, putative 0.0154 0.0712 0.6381
Brugia malayi Papain family cysteine protease containing protein 0.004 0.0131 0.0554
Brugia malayi cathepsin Z-like cysteine proteinase 0.0018 0.002 0.0075
Giardia lamblia Copper-transporting P-type ATPase 0.0026 0.0062 0.06
Entamoeba histolytica cysteine protease, putative 0.0018 0.002 0.0192
Mycobacterium tuberculosis Probable metal cation transporter P-type ATPase CtpV 0.0026 0.0062 0.0056
Loa Loa (eye worm) hypothetical protein 0.0067 0.0267 0.1195
Onchocerca volvulus Dual oxidase homolog 0.0026 0.006 0.0362
Trypanosoma brucei vacuolar-type Ca2+-ATPase 1 0.0094 0.0404 0.5375
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.0094 0.0404 0.3609
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0044 0.0152 0.0228
Loa Loa (eye worm) hypothetical protein 0.0019 0.0023 0.0101
Onchocerca volvulus Huntingtin homolog 0.012 0.054 0.4746
Loa Loa (eye worm) AGC/RSK/RSK protein kinase 0.0095 0.041 0.1835
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.01 0.0877
Loa Loa (eye worm) hypothetical protein 0.0056 0.0212 0.0948
Echinococcus granulosus Chromobox protein 3 0.0034 0.01 0.0236
Echinococcus multilocularis protein patched 0.0042 0.0139 0.0326
Trypanosoma brucei DNA polymerase kappa, putative 0.0061 0.0235 0.3113
Schistosoma mansoni atypical protein kinase C 0.0162 0.075 0.1765
Trypanosoma cruzi protein farnesyltransferase, putative 0.0029 0.0076 0.0112
Brugia malayi Cathepsin L-like precursor 0.0034 0.0101 0.0426
Leishmania major cathepsin L-like protease 0.0056 0.0212 0.2802
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0139 0.1222
Echinococcus multilocularis serine:threonine protein kinase N2 0.0095 0.041 0.0966
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.0095 0.041 0.1835
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0111 0.0491 0.1155
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0044 0.0152 0.2
Echinococcus multilocularis lamin dm0 0.0026 0.0062 0.0147
Brugia malayi Cathepsin L-like precursor 0.0056 0.0212 0.0906
Trypanosoma cruzi cysteine peptidase, putative 0.0148 0.0682 0.1039
Leishmania major copper-transporting ATPase-like protein, putative 0.0026 0.0062 0.0789
Echinococcus multilocularis phosphoserine phosphatase 0.0017 0.0012 0.0029
Leishmania major cytochrome p450-like protein 0.0016 0.0007 0.0051
Trypanosoma cruzi PAB1-binding protein , putative 0.0051 0.0187 0.0282
Schistosoma mansoni patched 1 0.0042 0.0139 0.0326
Leishmania major calcium-transporting ATPase, putative 0.0067 0.0268 0.355
Brugia malayi Cytochrome P450 family protein 0.0026 0.0058 0.024
Plasmodium vivax ataxin-2 like protein, putative 0.0051 0.0187 0.2412
Schistosoma mansoni cellular tumor antigen P53 0.0049 0.0175 0.0411
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0015 0.0003 0.0007
Echinococcus granulosus cpg binding protein 0.003 0.0079 0.0186
Trichomonas vaginalis protein farnesyltransferase beta subunit, putative 0.0029 0.0076 0.0658
Echinococcus multilocularis phospholipid transporting ATPase VA 0.0017 0.0012 0.0029
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0018 0.002 0.0048
Trichomonas vaginalis protein farnesyltransferase alpha subunit, putative 0.004 0.0131 0.1153
Loa Loa (eye worm) AGC/PKC/IOTA protein kinase 0.0069 0.028 0.1252
Trypanosoma cruzi cruzipain precursor, putative 0.1301 0.6541 1
Trichomonas vaginalis ATPase, class VI, type 11C, putative 0.0026 0.0062 0.053
Onchocerca volvulus 0.0056 0.0212 0.1752
Leishmania major farnesyltransferase beta subunit 0.0029 0.0076 0.098
Loa Loa (eye worm) raf kinase 0.0067 0.0267 0.1195
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.005 0.018 0.0767
Loa Loa (eye worm) hypothetical protein 0.0387 0.1896 0.8481
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.008 0.0188
Schistosoma mansoni geranylgeranyl transferase type I beta subunit 0.0192 0.0905 0.213
Plasmodium vivax farnesyltransferase beta subunit, putative 0.0029 0.0076 0.0807
Brugia malayi MH2 domain containing protein 0.036 0.176 0.7611
Toxoplasma gondii calcium-translocating P-type ATPase, PMCA-type protein 0.0094 0.0404 0.1421
Brugia malayi hypothetical protein 0.012 0.054 0.2325
Loa Loa (eye worm) hypothetical protein 0.0067 0.0267 0.1195
Echinococcus granulosus Chromo domain 0.0034 0.01 0.0236
Schistosoma mansoni hypothetical protein 0.085 0.4248 1
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0023 0.0044 0.0038
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0049 0.0177 0.0753
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0359 0.1751 0.2422
Echinococcus multilocularis C2 calcium dependent membrane targeting 0.0079 0.033 0.0776
Loa Loa (eye worm) heterochromatin protein 1 0.015 0.0692 0.3095
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0023 0.0044 0.0116
Entamoeba histolytica protein kinase, putative 0.0095 0.041 0.4517
Brugia malayi CXXC zinc finger family protein 0.0028 0.0071 0.0295
Echinococcus granulosus ribosomal protein S6 kinase alpha 3 0.0095 0.041 0.0966
Trichomonas vaginalis CMGC family protein kinase 0.0052 0.0192 0.1706
Loa Loa (eye worm) calcium-transporting ATPase sarcoplasmic/endoplasmic reticulum type 0.0075 0.031 0.1387
Echinococcus multilocularis peroxidasin 0.0026 0.006 0.0141
Onchocerca volvulus 0.0136 0.0619 0.5474
Brugia malayi Valyl-tRNA synthetase 0.0034 0.01 0.0422
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0082 0.0343 0.0807
Onchocerca volvulus 0.0056 0.0212 0.1752
Loa Loa (eye worm) MH2 domain-containing protein 0.036 0.176 0.787
Loa Loa (eye worm) hypothetical protein 0.0049 0.0175 0.0781
Loa Loa (eye worm) phosphatidylinositol 3 0.0044 0.0152 0.068
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0095 0.0825
Loa Loa (eye worm) prenyltransferase alpha subunit repeat containing protein 0.004 0.0131 0.0586
Entamoeba histolytica cysteine protease, putative 0.004 0.0131 0.1418
Giardia lamblia Plasma membrane calcium-transporting ATPase 2 0.0067 0.0268 0.3579
Mycobacterium ulcerans metal cation transporter ATPase p-type CtpE 0.0026 0.0062 0.0055
Plasmodium falciparum cysteine proteinase falcipain 1 0.004 0.0131 0.1599
Brugia malayi protein kinase C II. 0.0174 0.0813 0.3508
Schistosoma mansoni cathepsin F (C01 family) 0.0034 0.0101 0.0238
Loa Loa (eye worm) hypothetical protein 0.0026 0.006 0.0267
Trichomonas vaginalis Heterochromatin protein, putative 0.0034 0.01 0.0877
Loa Loa (eye worm) hypothetical protein 0.003 0.008 0.0357
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0022 0.0172
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0052 0.0192 0.029
Loa Loa (eye worm) AGC/NDR protein kinase 0.0095 0.041 0.1835
Trichomonas vaginalis protein farnesyltransferase alpha subunit/RAB geranylgeranyl transferase alpha subunit, putative 0.0114 0.0509 0.4551
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0063 0.0248 0.111
Brugia malayi follicle stimulating hormone receptor 0.0235 0.112 0.4841
Echinococcus granulosus RUN 0.0019 0.0026 0.0061
Plasmodium falciparum protein farnesyltransferase subunit beta 0.0029 0.0076 0.0807
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0034 0.0101 0.0886
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0056 0.0212 0.1881
Mycobacterium tuberculosis Probable metal cation transporter P-type ATPase A CtpF 0.0035 0.0106 0.0118
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.002 0.0156
Loa Loa (eye worm) hypothetical protein 0.0026 0.006 0.0268
Toxoplasma gondii thioredoxin reductase 0.0141 0.0647 0.2302
Trypanosoma cruzi calcium-translocating P-type ATPase, putative 0.0037 0.0113 0.0169
Trypanosoma cruzi hypothetical protein, conserved 0.004 0.0131 0.0196
Echinococcus multilocularis Niemann Pick C1 protein 0.0138 0.063 0.1484
Echinococcus granulosus Smad4 0.0025 0.0052 0.0123
Plasmodium falciparum glutathione reductase 0.0049 0.0177 0.2263
Trypanosoma brucei Protein prenyltransferase alpha subunit repeat, putative 0.004 0.0131 0.1716
Trypanosoma brucei P-type H+-ATPase, putative 0.0053 0.0198 0.2616
Loa Loa (eye worm) hypothetical protein 0.0026 0.006 0.0267
Brugia malayi Pleckstrin Homology Domain 0.0067 0.0267 0.1145
Loa Loa (eye worm) hypothetical protein 0.0034 0.0101 0.0453
Trypanosoma cruzi PAB1-binding protein , putative 0.0051 0.0187 0.0282
Trichomonas vaginalis AGC family protein kinase 0.0095 0.041 0.3666
Brugia malayi E1-E2 ATPase family protein 0.0053 0.0198 0.0846
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0024 0.0051 0.0641
Brugia malayi hypothetical protein 0.0019 0.0026 0.0101
Brugia malayi latrophilin 2 splice variant baaae 0.0034 0.01 0.0421
Trypanosoma cruzi plasma-membrane proton-efflux P-type ATPase, putative 0.0037 0.0113 0.0169
Trypanosoma brucei DNA damage repair protein, putative 0.0034 0.0102 0.1333
Toxoplasma gondii preprocathepsin c precursor, putative 0.0018 0.002 0.0028
Brugia malayi Animal haem peroxidase family protein 0.0026 0.006 0.0247
Echinococcus granulosus smad 0.0025 0.0052 0.0123
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.0019 0.0023 0.0036
Schistosoma mansoni polycystin 1-related 0.0019 0.0026 0.0061
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0049 0.0177 0.233
Schistosoma mansoni smad1 5 8 and 0.0025 0.0052 0.0123
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0022 0.0038 0.0153
Giardia lamblia NADH oxidase lateral transfer candidate 0.0049 0.0177 0.2263
Loa Loa (eye worm) hypothetical protein 0.0034 0.01 0.0447
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0034 0.01 0.0877
Trichomonas vaginalis pc-MYB2, putative 0.0086 0.0365 0.3263
Onchocerca volvulus 0.0067 0.0267 0.2257
Entamoeba histolytica cysteine protease, putative 0.004 0.0131 0.1418
Echinococcus multilocularis Polycystic kidney disease protein 0.0019 0.0026 0.0061
Echinococcus granulosus serine:threonine protein kinase N2 0.0095 0.041 0.0966
Echinococcus multilocularis Chromobox protein 3 0.0034 0.01 0.0236
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0056 0.0212 0.1881
Echinococcus granulosus Protein kinase C brain isozyme 0.0561 0.2781 0.6546
Wolbachia endosymbiont of Brugia malayi 4'-phosphopantetheinyl transferase 0.0023 0.0044 0.0023
Brugia malayi Protein cec-1. 0.0034 0.01 0.0422
Toxoplasma gondii E1-E2 ATPase subfamily protein 0.0037 0.0113 0.0366
Brugia malayi E1-E2 ATPase family protein 0.0026 0.0062 0.0255
Entamoeba histolytica cysteine protease, putative 0.004 0.0131 0.1418
Brugia malayi Protein kinase domain containing protein 0.0069 0.028 0.12
Onchocerca volvulus 0.0122 0.0549 0.4834
Treponema pallidum UDP-N-acetylglucosamine 1-carboxyvinyltransferase 0.1981 1 1
Toxoplasma gondii chromodomain helicase DNA binding protein CHD1/SWI2/SNF2 0.0034 0.01 0.0319
Schistosoma mansoni peroxidasin 0.0026 0.006 0.0141
Loa Loa (eye worm) hypothetical protein 0.0312 0.1512 0.6764
Toxoplasma gondii NADPH-glutathione reductase 0.0049 0.0177 0.0596
Entamoeba histolytica cysteine proteinase 2 0.004 0.0131 0.1418
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0049 0.0177 0.0416
Schistosoma mansoni unc-13 (munc13) 0.0079 0.033 0.0776
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0056 0.0212 0.1881
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0106 0.0929
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0106 0.0929
Brugia malayi MH2 domain containing protein 0.0025 0.0052 0.0215
Onchocerca volvulus 0.0026 0.0062 0.0385
Loa Loa (eye worm) cytochrome P450 family protein 0.0016 0.0007 0.003
Echinococcus multilocularis Ribosomal protein S6 kinase beta 2 0.0095 0.041 0.0966
Loa Loa (eye worm) animal heme peroxidase 0.0026 0.006 0.0267
Trypanosoma cruzi P-type H+-ATPase, putative 0.0037 0.0113 0.0169
Trypanosoma brucei cation-transporting ATPase, putative 0.0026 0.0062 0.0789
Trypanosoma cruzi copper-transporting ATPase, putative 0.0017 0.0012 0.0015
Schistosoma mansoni atpase class VI type 11c 0.0017 0.0012 0.0029
Trichomonas vaginalis Clan CA, family C1, cathepsin H-like cysteine peptidase 0.0018 0.002 0.0156
Onchocerca volvulus Cathepsin F homolog 0.0056 0.0212 0.1752
Echinococcus multilocularis geminin 0.085 0.4248 1
Onchocerca volvulus 0.0067 0.0267 0.2257
Toxoplasma gondii hypothetical protein 0.0114 0.0509 0.1801
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0049 0.0177 0.0133
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0095 0.0825
Trypanosoma cruzi calcium motive p-type ATPase, putative 0.0067 0.0268 0.0405
Echinococcus granulosus cation transporting atpase worm 0.0026 0.0062 0.0145
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0085 0.0361 0.1264
Plasmodium falciparum cysteine proteinase falcipain 3 0.0056 0.0212 0.2772
Brugia malayi RNA recognition motif domain containing protein 0.0063 0.0248 0.1062
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0049 0.0177 0.0266
Schistosoma mansoni hypothetical protein 0.085 0.4248 1
Echinococcus granulosus tar DNA binding protein 0.0063 0.0248 0.0584
Entamoeba histolytica deoxycytidyl transferase, putative 0.0111 0.0491 0.5408
Loa Loa (eye worm) hypothetical protein 0.0018 0.002 0.009
Loa Loa (eye worm) AGC/DMPK/GEK protein kinase 0.0095 0.041 0.1835
Loa Loa (eye worm) hypothetical protein 0.005 0.0183 0.0817
Loa Loa (eye worm) hypothetical protein 0.0018 0.002 0.009
Trypanosoma cruzi protein farnesyltransferase, putative 0.0029 0.0076 0.0112
Toxoplasma gondii cathepsin CPL 0.0056 0.0212 0.0724
Mycobacterium ulcerans metal cation-transporting p-type ATPase F, CtpF 0.0119 0.0531 0.0525
Onchocerca volvulus 0.0061 0.0238 0.1994
Trichomonas vaginalis chromobox protein, putative 0.0034 0.01 0.0877
Loa Loa (eye worm) RhoGAP domain-containing protein 0.0067 0.0267 0.1195
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.016 0.0741 0.3316
Toxoplasma gondii P-type ATPase4, putative 0.0084 0.0353 0.1235
Entamoeba histolytica cysteine protease, putative 0.0018 0.002 0.0192
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0062 0.053
Echinococcus multilocularis Chromo domain 0.0034 0.01 0.0236
Echinococcus multilocularis cathepsin b 0.0018 0.002 0.0048
Loa Loa (eye worm) animal heme peroxidase 0.0026 0.006 0.0267
Trichomonas vaginalis Clan CA, family C1, cathepsin L or H-like cysteine peptidase 0.0018 0.002 0.0156
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.0041 0.0135 0.0446
Trypanosoma brucei hypothetical protein, conserved 0.004 0.0131 0.1716
Leishmania major cathepsin L-like protease 0.0056 0.0212 0.2802
Echinococcus granulosus chromobox protein 1 0.015 0.0692 0.1629
Loa Loa (eye worm) Na,K-ATPase alpha subunit 0.0084 0.0353 0.1577
Echinococcus granulosus dnaJ subfamily B 0.0402 0.1971 0.4639
Loa Loa (eye worm) hypothetical protein 0.0034 0.0101 0.0453
Mycobacterium ulcerans metal cation transporter p-type ATPase, CtpV 0.0026 0.0062 0.0055
Schistosoma mansoni alpha-glucosidase 0.0138 0.0628 0.1479
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0034 0.01 0.108
Echinococcus granulosus sarco:endoplasmic reticulum calcium ATPase 0.0119 0.0531 0.1251
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0056 0.0212 0.1881
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.0094 0.0404 0.3609
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0015 0.0005 0.0008
Echinococcus granulosus protein kinase c epsilon type 0.0174 0.0813 0.1913
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0106 0.0929
Plasmodium falciparum glutathione reductase 0.0141 0.0647 0.9054
Trypanosoma cruzi DNA damage repair protein, putative 0.0034 0.0102 0.0152
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0108 0.0948
Brugia malayi hypothetical protein 0.0232 0.1109 0.4792
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0036 0.0108 0.0348
Loa Loa (eye worm) hypothetical protein 0.0067 0.0267 0.1195
Echinococcus granulosus ribosomal protein s6 kinase beta 1 0.0095 0.041 0.0966
Echinococcus granulosus mothers against decapentaplegic 5 0.0025 0.0052 0.0123
Loa Loa (eye worm) sodium potassium adenosine triphosphatase 0.0037 0.0113 0.0506
Schistosoma mansoni serine/threonine protein kinase 0.0067 0.0267 0.0629
Trypanosoma cruzi P-type H+-ATPase, putative 0.0053 0.0198 0.0299
Leishmania major DNA polymerase kappa, putative 0.0034 0.0102 0.1333
Plasmodium falciparum thioredoxin reductase 0.0141 0.0647 0.9054
Echinococcus multilocularis cation transporting atpase worm 0.0026 0.0062 0.0145
Trichomonas vaginalis r2r3-MYB transcription factor, putative 0.0086 0.0365 0.3263
Schistosoma mansoni protein farnesyltransferase subunit beta 0.0029 0.0076 0.0179
Mycobacterium ulcerans 3-phosphoshikimate 1-carboxyvinyltransferase 0.0559 0.2767 0.2762
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0049 0.0177 0.233
Brugia malayi calcium ATPase 0.0037 0.0113 0.0478
Loa Loa (eye worm) hypothetical protein 0.0034 0.0101 0.0453
Schistosoma mansoni rab6-interacting 0.0019 0.0026 0.0061
Trypanosoma brucei glucosidase, putative 0.0036 0.0108 0.1412
Entamoeba histolytica hypothetical protein 0.0144 0.066 0.7283
Onchocerca volvulus Peroxidasin homolog 0.0026 0.006 0.0362
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0056 0.0212 0.0499
Trypanosoma cruzi DNA polymerase kappa, putative 0.0137 0.0623 0.0949
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0067 0.0267 0.0629
Schistosoma mansoni diacylglycerol kinase theta 0.0067 0.0267 0.0629
Echinococcus granulosus cathepsin L 0.0018 0.002 0.0048
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0019 0.0022 0.0025
Entamoeba histolytica cysteine protease, putative 0.004 0.0131 0.1418
Trichomonas vaginalis AGC family protein kinase 0.0095 0.041 0.3666
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0049 0.0177 0.017
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0037 0.0118 0.1034
Echinococcus multilocularis RUN 0.0019 0.0026 0.0061
Chlamydia trachomatis phosphoshikimate 1-carboxyl vinyltransferase 0.0559 0.2767 0.2735
Echinococcus granulosus TGF beta signal transducer SmadC 0.0025 0.0052 0.0123
Loa Loa (eye worm) hypothetical protein 0.0026 0.006 0.0267
Loa Loa (eye worm) hypothetical protein 0.0026 0.006 0.0267
Loa Loa (eye worm) helicase 0.0034 0.01 0.0449
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0036 0.0108 0.1167
Brugia malayi intermediate filament protein 0.0026 0.0062 0.0257
Loa Loa (eye worm) hypothetical protein 0.0026 0.006 0.0267
Trichomonas vaginalis AGC family protein kinase 0.0095 0.041 0.3666
Trypanosoma brucei DNA polymerase kappa, putative 0.0137 0.0623 0.8317
Echinococcus granulosus Alpha N acetylgalactosaminidase 0.0101 0.0439 0.1034
Echinococcus granulosus phospholipid transporting ATPase IIB 0.0026 0.0062 0.0145
Plasmodium falciparum DNA repair protein REV1, putative 0.0034 0.0102 0.1187
Schistosoma mansoni serine/threonine protein kinase 0.0561 0.2781 0.6546
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0049 0.0177 0.233
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0056 0.0212 0.1881
Echinococcus granulosus protein prenyltransferase alpha subunit 0.004 0.0131 0.0308
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0028 0.0071 0.0168
Leishmania major cathepsin L-like protease 0.0148 0.0682 0.9102
Trichomonas vaginalis AGC family protein kinase 0.0095 0.041 0.3666
Entamoeba histolytica recQ family helicase, putative 0.0024 0.0051 0.0529
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0018 0.002 0.0048
Brugia malayi Prenyltransferase and squalene oxidase repeat family protein 0.0029 0.0076 0.0317
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0148 0.0682 0.9102
Trypanosoma brucei Protein prenyltransferase alpha subunit repeat, putative 0.004 0.0131 0.1716
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0037 0.0115 0.1013
Trypanosoma cruzi cation-transporting ATPase, putative 0.0026 0.0062 0.009
Loa Loa (eye worm) RasGEF domain-containing protein 0.0067 0.0267 0.1195
Schistosoma mansoni serine/threonine protein kinase 0.0561 0.2781 0.6546
Trichomonas vaginalis CMGC family protein kinase 0.0052 0.0192 0.1706
Trypanosoma brucei DNA polymerase kappa, putative 0.0061 0.0235 0.3113
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0148 0.0682 0.9102
Echinococcus multilocularis cation transporting ATPase 13A1 0.0026 0.0062 0.0145
Leishmania major P-type ATPase, putative 0.0077 0.0319 0.4238
Loa Loa (eye worm) hypothetical protein 0.0122 0.055 0.2459
Trypanosoma brucei DNA polymerase kappa, putative 0.0137 0.0623 0.8317
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0148 0.0682 0.9102
Onchocerca volvulus 0.0049 0.0175 0.1411
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0056 0.0212 0.1881
Onchocerca volvulus 0.0034 0.0101 0.0741
Trichomonas vaginalis PIKK family atypical protein kinase 0.0044 0.0152 0.1343
Echinococcus granulosus dna polymerase kappa 0.0137 0.0623 0.1467
Echinococcus multilocularis protein kinase c eta type 0.0067 0.0267 0.0629
Brugia malayi cathepsin F-like cysteine proteinase 0.0022 0.0038 0.0153
Trypanosoma brucei DNA polymerase kappa, putative 0.0117 0.0524 0.6978
Entamoeba histolytica hypothetical protein 0.0067 0.0267 0.2931
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0052 0.0192 0.029
Echinococcus granulosus mitogen activated protein kinase 0.0052 0.0192 0.0453
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.004 0.0131 0.0308
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0072 0.0295 0.0695
Schistosoma mansoni serine/threonine protein kinase 0.0095 0.041 0.0966
Loa Loa (eye worm) calcium ATPase 0.002 0.0028 0.0126
Trichomonas vaginalis AGC family protein kinase 0.0095 0.041 0.3666
Leishmania major calcium motive p-type ATPase, putative 0.0067 0.0268 0.355
Mycobacterium tuberculosis Probable dehydrogenase 0.0323 0.1568 0.2165
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.002 0.0156
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0056 0.0212 0.1881
Toxoplasma gondii melibiase subfamily protein 0.0101 0.0439 0.1549
Echinococcus granulosus cation transporting ATPase 13A1 0.0026 0.0062 0.0145
Schistosoma mansoni loxhd1 0.0019 0.0026 0.0061
Onchocerca volvulus 0.0093 0.0398 0.3455
Mycobacterium tuberculosis Probable reductase 0.0323 0.1568 0.2165
Schistosoma mansoni type V p-type atpase isoform 0.0026 0.0062 0.0145
Brugia malayi hypothetical protein 0.0122 0.055 0.237
Entamoeba histolytica plasma membrane calcium-transporting ATPase, putative 0.002 0.0028 0.028
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0036 0.0108 0.0255
Echinococcus multilocularis ribosomal protein S6 kinase alpha 3 0.0095 0.041 0.0966
Loa Loa (eye worm) hypothetical protein 0.0022 0.0038 0.0171
Trichomonas vaginalis protein farnesyltransferase alpha subunit/RAB geranylgeranyl transferase alpha subunit, putative 0.0154 0.0712 0.6381
Brugia malayi Niemann-Pick C1 protein precursor 0.0097 0.0419 0.1805
Toxoplasma gondii shikimate dehydrogenase substrate binding domain-containing protein 0.0559 0.2767 1
Echinococcus multilocularis GPCR, family 2 0.0016 0.0007 0.0017
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0052 0.0192 0.029
Trichomonas vaginalis CMGC family protein kinase 0.0052 0.0192 0.1706
Echinococcus granulosus geminin 0.085 0.4248 1
Loa Loa (eye worm) hypothetical protein 0.0018 0.002 0.009
Entamoeba histolytica protein farnesyltransferase beta subunit, putative 0.0029 0.0076 0.0811
Echinococcus granulosus plasma membrane calcium transporting ATPase 2 0.0094 0.0404 0.0951
Loa Loa (eye worm) hypothetical protein 0.0022 0.0038 0.0171
Brugia malayi RhoGAP domain containing protein 0.0067 0.0267 0.1145
Entamoeba histolytica cysteine proteinase, putative 0.004 0.0131 0.1418
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0089 0.0381 0.3297
Brugia malayi exodeoxyribonuclease III family protein 0.0019 0.0022 0.0083
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0034 0.01 0.0319
Loa Loa (eye worm) hypothetical protein 0.0089 0.0381 0.1704
Loa Loa (eye worm) hypothetical protein 0.0232 0.1109 0.496
Trypanosoma cruzi P-type H+-ATPase, putative 0.0053 0.0198 0.0299
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.006 0.0518
Echinococcus granulosus cathepsin l1 0.0034 0.0101 0.0238
Loa Loa (eye worm) transcription factor SMAD2 0.036 0.176 0.787
Brugia malayi Protein kinase domain containing protein 0.0095 0.041 0.1765
Plasmodium falciparum chromodomain-helicase-DNA-binding protein 1 homolog, putative 0.0034 0.01 0.1158
Schistosoma mansoni lipoxygenase 0.0054 0.0203 0.0479
Brugia malayi Cathepsin L-like precursor 0.0056 0.0212 0.0906
Brugia malayi RhoGEF domain containing protein 0.0067 0.0267 0.1145
Trichomonas vaginalis PIKK family atypical protein kinase 0.003 0.0078 0.0678
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0019 0.0022 0.0029
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0049 0.0177 0.233
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0056 0.0212 0.1881
Echinococcus granulosus peroxidasin 0.0026 0.006 0.0141
Echinococcus granulosus microtubule associated protein 2 0.0678 0.3375 0.7944
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.002 0.0156
Echinococcus multilocularis dna polymerase eta 0.0162 0.0749 0.1763
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0056 0.0212 0.1881
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0019 0.0022 0.0052
Trichomonas vaginalis PIKK family atypical protein kinase 0.0044 0.0152 0.1343
Trypanosoma cruzi calcium-translocating P-type ATPase, putative 0.0066 0.0261 0.0395
Echinococcus granulosus dna polymerase eta 0.0162 0.0749 0.1763
Echinococcus multilocularis mothers against decapentaplegic 5 0.0025 0.0052 0.0123
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.002 0.0156
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0023 0.0044 0.0031
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0323 0.1568 0.2165
Entamoeba histolytica protein kinase, putative 0.0095 0.041 0.4517
Plasmodium vivax vivapain-1 0.004 0.0131 0.1599
Toxoplasma gondii heavy metal translocating P-type ATPase subfamily protein 0.0026 0.0062 0.0179
Trypanosoma brucei unspecified product 0.0076 0.0316 0.4195
Loa Loa (eye worm) hypothetical protein 0.0026 0.006 0.0267
Onchocerca volvulus 0.0056 0.0212 0.1752
Loa Loa (eye worm) hypothetical protein 0.0034 0.01 0.0449
Echinococcus multilocularis myotubularin protein 13 0.0067 0.0267 0.0629
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0044 0.0152 0.0228
Schistosoma mansoni protein kinase C 0.0079 0.033 0.0776
Brugia malayi MH2 domain containing protein 0.0025 0.0052 0.0215
Giardia lamblia Potassium-transporting ATPase alpha chain 1 0.0067 0.0268 0.3579
Schistosoma mansoni serine/threonine protein kinase 0.0069 0.028 0.0659
Brugia malayi Pre-SET motif family protein 0.0205 0.097 0.4192
Trypanosoma brucei DNA polymerase kappa, putative 0.0137 0.0623 0.8317
Entamoeba histolytica diacylglycerol kinase, putative 0.0067 0.0267 0.2931
Loa Loa (eye worm) hypothetical protein 0.0034 0.01 0.0449
Toxoplasma gondii prenyltransferase and squalene oxidase repeat-containing protein 0.0029 0.0076 0.0231
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0148 0.0682 0.9102
Entamoeba histolytica cysteine protease, putative 0.0018 0.002 0.0192
Onchocerca volvulus 0.0056 0.0212 0.1752
Brugia malayi Intermediate filament tail domain containing protein 0.0026 0.0062 0.0257
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0056 0.0212 0.1881
Echinococcus granulosus chromobox protein 2 0.0034 0.01 0.0236
Trichomonas vaginalis DNA helicase recq1, putative 0.0045 0.0158 0.1396
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0036 0.0111 0.0467
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0019 0.0023 0.0101
Echinococcus multilocularis lipoxygenase domain containing protein 0.0019 0.0026 0.0061
Trypanosoma cruzi cytochrome P450, putative 0.0016 0.0007 0.0006
Loa Loa (eye worm) hypothetical protein 0.0026 0.0062 0.0276
Onchocerca volvulus Peroxidasin homolog 0.0026 0.006 0.0362
Echinococcus granulosus calcium transporting atpase 0.0102 0.0446 0.1051
Entamoeba histolytica cysteine protease, putative 0.004 0.0131 0.1418
Schistosoma mansoni hypothetical protein 0.004 0.0131 0.0308
Trypanosoma brucei protein farnesyltransferase alpha subunit, putative 0.004 0.0131 0.1716
Trypanosoma cruzi cytochrome P450, putative 0.0016 0.0007 0.0006
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0323 0.1568 0.2165
Trypanosoma cruzi DNA polymerase kappa, putative 0.0137 0.0623 0.0949
Trypanosoma brucei protein kinase, putative 0.0052 0.0192 0.2541
Loa Loa (eye worm) hypothetical protein 0.0034 0.01 0.0449
Loa Loa (eye worm) hypothetical protein 0.0018 0.002 0.009
Onchocerca volvulus Peroxidase homolog 0.0026 0.006 0.0362
Brugia malayi hypothetical protein 0.0051 0.0187 0.0798
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.003 0.0082 0.0251
Trichomonas vaginalis geranylgeranyl transferase type I beta subunit, putative 0.0029 0.0076 0.0658
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0049 0.0177 0.0266
Plasmodium falciparum LCCL domain-containing protein 0.0019 0.0026 0.0085
Echinococcus multilocularis phosphoserine phosphatase 0.0017 0.0012 0.0029
Echinococcus granulosus cathepsin L cysteine protease 0.004 0.0131 0.0308
Trypanosoma brucei vacuolar-type Ca2+-ATPase 2 0.0094 0.0404 0.5375
Leishmania major trypanothione reductase 0.0141 0.0647 0.8627
Loa Loa (eye worm) hypothetical protein 0.003 0.0082 0.0367
Brugia malayi Hr1 repeat family protein 0.0095 0.041 0.1765
Plasmodium vivax unspecified product 0.0022 0.0038 0.026
Schistosoma mansoni protein kinase C mu 0.0067 0.0267 0.0629
Entamoeba histolytica cysteine proteinase 1, putative 0.004 0.0131 0.1418
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0018 0.002 0.0027
Trichomonas vaginalis conserved hypothetical protein 0.0055 0.0208 0.1849
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.0067 0.0267 0.0629
Trypanosoma cruzi cysteine proteinase, putative 0.004 0.0131 0.0196
Onchocerca volvulus Chorion peroxidase homolog 0.0026 0.006 0.0362
Echinococcus multilocularis phosphoserine phosphatase 0.0017 0.0012 0.0029
Brugia malayi SET domain containing protein 0.0036 0.0109 0.046
Schistosoma mansoni transcription factor LCR-F1 0.0144 0.066 0.1553
Brugia malayi cathepsin L precursor 0.0018 0.002 0.0075
Loa Loa (eye worm) hypothetical protein 0.0018 0.002 0.009
Brugia malayi Probable cation-transporting ATPase C10C6.6 in chromosome IV 0.0026 0.0062 0.0255
Trypanosoma cruzi cysteine peptidase, putative 0.004 0.0131 0.0196
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0019 0.0022 0.0256
Schistosoma mansoni cpg binding protein 0.003 0.0079 0.0186
Echinococcus multilocularis Ankyrin repeat domain containing protein 0.0088 0.0377 0.0886
Trypanosoma brucei DNA damage repair protein, putative 0.0034 0.0102 0.1333
Brugia malayi Phorbol esters/diacylglycerol binding domain 0.0069 0.028 0.12
Echinococcus granulosus Polycystic kidney disease protein 0.0019 0.0026 0.0061
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0095 0.0825
Brugia malayi Cathepsin L-like precursor 0.0056 0.0212 0.0906
Trypanosoma cruzi phospholipid-transporting ATPase-like protein, putative 0.0017 0.0012 0.0015
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0031 0.0083 0.0913
Brugia malayi MAP kinase sur-1 0.0052 0.0192 0.0821
Brugia malayi Protein prenyltransferase alpha subunit repeat containing protein 0.0154 0.0712 0.3072
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.003 0.008 0.0245
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0016 0.0007 0.0017
Entamoeba histolytica Plasma membrane calcium-transporting ATPase, putative 0.0094 0.0404 0.4447
Echinococcus granulosus protein kinase c iota type 0.0162 0.075 0.1765
Trypanosoma cruzi cysteine peptidase, putative 0.0148 0.0682 0.1039
Echinococcus multilocularis cathepsin L 0.0018 0.002 0.0048
Trichomonas vaginalis DNA polymerase eta, putative 0.0137 0.0623 0.5585
Trypanosoma brucei DNA polymerase kappa, putative 0.0137 0.0623 0.8317
Loa Loa (eye worm) hypothetical protein 0.0026 0.006 0.0267
Echinococcus granulosus Na:K ATPase alpha subunit 0.0067 0.0268 0.063
Entamoeba histolytica hypothetical protein 0.0034 0.01 0.108
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0018 0.002 0.0156
Trichomonas vaginalis maltase-glucoamylase, putative 0.0036 0.0108 0.0948
Schistosoma mansoni cpg binding protein 0.003 0.0079 0.0186
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0108 0.0161
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0021 0.0034 0.0414
Trichomonas vaginalis set domain proteins, putative 0.0233 0.1114 1
Echinococcus multilocularis serine:threonine protein kinase N2 0.0095 0.041 0.0966
Toxoplasma gondii diacylglycerol kinase, putative 0.0067 0.0267 0.0925
Schistosoma mansoni rab6-interacting 0.0019 0.0026 0.0061
Onchocerca volvulus 0.0026 0.006 0.0362
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0044 0.0152 0.2
Brugia malayi Associated with TFs and helicases family protein 0.0034 0.01 0.0422
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0049 0.0177 0.0266
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0106 0.0929
Echinococcus multilocularis sarco:endoplasmic reticulum calcium ATPase 0.0119 0.0531 0.1251
Plasmodium vivax SET domain protein, putative 0.003 0.008 0.0862
Trypanosoma cruzi hypothetical protein, conserved 0.0034 0.0102 0.0152
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0023 0.0044 0.035
Schistosoma mansoni plasma membrane calcium-transporting atpase 0.0077 0.0319 0.0751
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0019 0.0022 0.0029
Entamoeba histolytica cysteine protease, putative 0.0018 0.002 0.0192
Loa Loa (eye worm) TAR-binding protein 0.0063 0.0248 0.111
Trypanosoma brucei DNA polymerase IV, putative 0.013 0.059 0.7875
Brugia malayi CHD4 protein 0.0036 0.0108 0.0458
Brugia malayi Na,K-ATPase alpha subunit 0.0084 0.0353 0.1515
Entamoeba histolytica cysteine protease, putative 0.004 0.0131 0.1418
Onchocerca volvulus 0.0122 0.0549 0.4834
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0049 0.0177 0.0266
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0049 0.0177 0.2263
Echinococcus multilocularis geranylgeranyl transferase type 2 subunit alpha 0.004 0.0131 0.0308
Echinococcus multilocularis Rac GTPase activating protein 1 0.0067 0.0267 0.0629
Trypanosoma brucei cytochrome P450, putative 0.0016 0.0007 0.0051
Loa Loa (eye worm) hypothetical protein 0.005 0.018 0.0804
Loa Loa (eye worm) cathepsin B 0.0018 0.002 0.009
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0056 0.0212 0.0499
Trypanosoma brucei chrX additional, unordered contigs 0.0034 0.0102 0.1333
Toxoplasma gondii plasma membrane-type Ca(2+)-ATPase A1 PMCAA1 0.0077 0.0319 0.1113
Echinococcus granulosus lipoxygenase domain containing protein 0.0019 0.0026 0.0061
Trypanosoma cruzi DNA polymerase eta, putative 0.0162 0.0749 0.1141
Loa Loa (eye worm) Ras association domain family 1 isoform A 0.0067 0.0267 0.1195
Entamoeba histolytica hypothetical protein 0.0023 0.0044 0.046
Toxoplasma gondii Rab geranylgeranyl transferase type II beta subunit, putative 0.0029 0.0076 0.0231
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.0018 0.002 0.0048
Schistosoma mansoni plasma membrane calcium-transporting atpase 0.0077 0.0319 0.0751
Loa Loa (eye worm) hypothetical protein 0.0067 0.0269 0.1202
Toxoplasma gondii target of rapamycin (TOR), putative 0.0033 0.0095 0.0298
Schistosoma mansoni hypothetical protein 0.0016 0.0007 0.0017
Schistosoma mansoni serine/threonine protein kinase 0.0052 0.0192 0.0453
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.0094 0.0404 0.3609
Loa Loa (eye worm) animal heme peroxidase 0.0026 0.006 0.0267
Loa Loa (eye worm) animal heme peroxidase 0.0026 0.006 0.0267
Trypanosoma brucei calcium-translocating P-type ATPase 0.0102 0.0446 0.5946
Brugia malayi hypothetical protein 0.0144 0.066 0.2846
Entamoeba histolytica hypothetical protein 0.0034 0.01 0.108
Trypanosoma cruzi trypanothione reductase, putative 0.0141 0.0647 0.0985
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0025 0.0052 0.0123
Loa Loa (eye worm) hypothetical protein 0.0026 0.006 0.0267
Brugia malayi Cathepsin L-like precursor 0.0022 0.0038 0.0153
Schistosoma mansoni hypothetical protein 0.0051 0.0186 0.0438
Brugia malayi Protein kinase domain containing protein 0.0095 0.041 0.1765
Schistosoma mansoni cathepsin C 0.0018 0.002 0.0048
Trichomonas vaginalis r2r3-MYB transcription factor, putative 0.0087 0.0368 0.3282
Trypanosoma cruzi cysteine protease, putative 0.004 0.0131 0.0196
Echinococcus multilocularis survival motor neuron protein 1 0.0232 0.1109 0.261
Brugia malayi hypothetical protein 0.0033 0.0095 0.04
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0044 0.0152 0.2
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.003 0.008 0.0188
Echinococcus multilocularis cathepsin L cysteine protease 0.0056 0.0212 0.0499
Echinococcus granulosus Serine/threonine-protein kinase Genghis Khan 0.0069 0.028 0.0659
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0049 0.0177 0.0596
Echinococcus granulosus C2 calcium dependent membrane targeting 0.0079 0.033 0.0776
Wolbachia endosymbiont of Brugia malayi UDP-N-acetylglucosamine 1-carboxyvinyltransferase 0.1981 1 1
Trichomonas vaginalis geranylgeranyl transferase type beta subunit, putative 0.0029 0.0076 0.0658
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0019 0.0022 0.0211
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0044 0.0152 0.2
Brugia malayi Protein kinase domain containing protein 0.0017 0.0012 0.004
Trypanosoma brucei cysteine peptidase C (CPC) 0.0018 0.002 0.0232
Echinococcus multilocularis protein farnesyltransferase subunit beta 0.0029 0.0076 0.0179
Leishmania major geranylgeranyltransferase, putative 0.0029 0.0076 0.098
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.004 0.0131 0.1715
Entamoeba histolytica cysteine protease, putative 0.0056 0.0212 0.2318
Schistosoma mansoni hypothetical protein 0.0283 0.1367 0.3217
Echinococcus multilocularis cathepsin b 0.0018 0.002 0.0048
Brugia malayi Glycosyl hydrolases family 31 protein 0.0036 0.0108 0.0456
Loa Loa (eye worm) hypothetical protein 0.0136 0.0619 0.277
Schistosoma mansoni hypothetical protein 0.0047 0.0169 0.0397
Trichomonas vaginalis MYB72, putative 0.0086 0.0365 0.3263
Echinococcus granulosus X box binding protein 1 0.0283 0.1367 0.3217
Echinococcus granulosus cathepsin b 0.0018 0.002 0.0048
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0019 0.0023 0.0053
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0049 0.0177 0.233
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0111 0.0491 0.1155
Echinococcus granulosus cathepsin l1 0.0056 0.0212 0.0499
Loa Loa (eye worm) hypothetical protein 0.0162 0.0749 0.335
Mycobacterium ulcerans hypothetical protein 0.0034 0.0102 0.0096
Loa Loa (eye worm) hypothetical protein 0.0029 0.0076 0.034
Brugia malayi glutathione reductase 0.0141 0.0647 0.2788
Entamoeba histolytica myb-like DNA-binding domain containing protein 0.0086 0.0365 0.4021
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.01 0.0877
Trichomonas vaginalis cation-transporting ATPase, putative 0.0053 0.0198 0.1757
Echinococcus multilocularis expressed conserved protein 0.0091 0.039 0.0917
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0056 0.0212 0.1881
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0034 0.0101 0.0886
Trypanosoma brucei DNA polymerase kappa, putative 0.0137 0.0623 0.8317
Schistosoma mansoni copper ABC transporter ATPase 0.0026 0.0062 0.0145
Giardia lamblia DINP protein human, muc B family 0.0117 0.0524 0.7276
Leishmania major alpha glucosidase II subunit, putative 0.0036 0.0108 0.1412
Trypanosoma brucei unspecified product 0.013 0.059 0.7875
Echinococcus granulosus Niemann Pick C1 protein 0.0097 0.0419 0.0987
Echinococcus granulosus cathepsin l cysteine peptidase 0.0056 0.0212 0.0499
Toxoplasma gondii cathepsin CPC2 0.0018 0.002 0.0028
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0056 0.0212 0.1881
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0108 0.0161
Leishmania major DNA polymerase eta, putative 0.0085 0.0361 0.4796
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0049 0.0177 0.0416
Plasmodium vivax unspecified product 0.004 0.0131 0.1599
Echinococcus granulosus calcium transporting ATPase type 2C member 0.0119 0.0531 0.1251
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0018 0.002 0.0048
Trichomonas vaginalis cation-transporting ATPase fungi, putative 0.0094 0.0404 0.3609
Entamoeba histolytica phospholipid-transporting P-type ATPase, putative 0.0026 0.0062 0.0652
Schistosoma mansoni multiple ankyrin repeats single kh domain protein 0.0088 0.0377 0.0886
Trichomonas vaginalis mercuric reductase, putative 0.0049 0.0177 0.1564
Schistosoma mansoni serine/threonine protein kinase 0.0095 0.041 0.0966
Mycobacterium tuberculosis Probable UDP-N-acetylglucosamine 1-carboxyvinyltransferase MurA 0.1423 0.716 1
Mycobacterium tuberculosis Cation transporter P-type ATPase a CtpA 0.0026 0.0062 0.0056
Trypanosoma cruzi protein farnesyltransferase alpha subunit, putative 0.004 0.0131 0.0196
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0056 0.0212 0.1881
Trichomonas vaginalis geranylgeranyl transferase type II beta subunit, putative 0.0029 0.0076 0.0658
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0067 0.0267 0.0629
Onchocerca volvulus Huntingtin homolog 0.012 0.054 0.4746
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0019 0.0022 0.0098
Loa Loa (eye worm) hypothetical protein 0.0026 0.006 0.0267
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0049 0.0177 0.233
Loa Loa (eye worm) prenyltransferase alpha subunit repeat containing protein 0.0154 0.0712 0.3184
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0049 0.0177 0.2263
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0018 0.0021 0.0241
Brugia malayi Bloom's syndrome protein homolog 0.0045 0.0158 0.0672
Schistosoma mansoni protein farnesyltransferase alpha subunit 0.0154 0.0712 0.1676
Echinococcus granulosus cathepsin L cysteine proteinase 0.0056 0.0212 0.0499
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0023 0.0044 0.035
Brugia malayi MH1 domain containing protein 0.0025 0.0052 0.0215
Trypanosoma cruzi plasma membrane Ca2+ ATPase 0.0094 0.0404 0.0613
Schistosoma mansoni cathepsin F (C01 family) 0.0056 0.0212 0.0499
Echinococcus multilocularis Niemann Pick C1 protein 0.0097 0.0419 0.0987
Loa Loa (eye worm) Smad1 0.0025 0.0052 0.0234
Loa Loa (eye worm) hypothetical protein 0.0122 0.0549 0.2457
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.008 0.0188
Brugia malayi C1-like domain containing protein 0.0069 0.028 0.12
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0049 0.0177 0.0155
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.0018 0.002 0.0048
Leishmania major DNA polymerase eta, putative 0.0162 0.0749 1
Entamoeba histolytica diacylglycerol kinase, putative 0.0067 0.0267 0.2931
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0023 0.0044 0.0103
Brugia malayi cathepsin F-like cysteine proteinase 0.0018 0.002 0.0075
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0023 0.0044 0.0038
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0049 0.0177 0.0217
Brugia malayi protein kinase C3,putative 0.0069 0.028 0.12
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0025 0.0052 0.0123

Activities

Activity type Activity value Assay description Source Reference
Log Ko = 0.05 Lipophilicity (log Ko) ChEMBL. 9599229
MBC (functional) = 8 ug ml-1 Antibacterial activity against Helicobacter pylori strain. ChEMBL. 9599229

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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