Detailed information for compound 75391

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 612.805 | Formula: C27H44N6O6S2
  • H donors: 7 H acceptors: 6 LogP: -1.03 Rotable bonds: 23
    Rule of 5 violations (Lipinski): 3
  • SMILES: NCCCC[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)O)CCSC)Cc1ccccc1)C(C)C)S)N
  • InChi: 1S/C27H44N6O6S2/c1-16(2)21(32-25(37)26(40)33-22(34)18(29)11-7-8-13-28)24(36)31-20(15-17-9-5-4-6-10-17)23(35)30-19(27(38)39)12-14-41-3/h4-6,9-10,16,18-21,26,40H,7-8,11-15,28-29H2,1-3H3,(H,30,35)(H,31,36)(H,32,37)(H,33,34)(H,38,39)/t18-,19+,20+,21+,26+/m1/s1
  • InChiKey: DFNOKXHMHRDRNE-QDKCGITRSA-N  

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Rattus norvegicus Protein farnesyltransferase Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Trichomonas vaginalis geranylgeranyl transferase type II beta subunit, putative Get druggable targets OG5_128081 All targets in OG5_128081
Schistosoma mansoni protein farnesyltransferase subunit beta Get druggable targets OG5_128081 All targets in OG5_128081
Giardia lamblia Prenyltransferase Get druggable targets OG5_128081 All targets in OG5_128081
Trichomonas vaginalis geranylgeranyl transferase type II beta subunit, putative Get druggable targets OG5_128081 All targets in OG5_128081
Plasmodium berghei protein farnesyltransferase subunit beta, putative Get druggable targets OG5_128081 All targets in OG5_128081
Trypanosoma cruzi protein farnesyltransferase, putative Get druggable targets OG5_128081 All targets in OG5_128081
Trichomonas vaginalis geranylgeranyl transferase type II beta subunit, putative Get druggable targets OG5_128081 All targets in OG5_128081
Plasmodium yoelii Prenyltransferase and squalene oxidase repeat, putative Get druggable targets OG5_128081 All targets in OG5_128081
Cryptosporidium parvum protein geranyl-geranyltransferase beta subunit Get druggable targets OG5_128081 All targets in OG5_128081
Trichomonas vaginalis geranylgeranyl transferase type beta subunit, putative Get druggable targets OG5_128081 All targets in OG5_128081
Plasmodium falciparum protein farnesyltransferase subunit beta Get druggable targets OG5_128081 All targets in OG5_128081
Theileria parva farnesyltransferase beta subunit, putative Get druggable targets OG5_128081 All targets in OG5_128081
Plasmodium knowlesi protein farnesyltransferase subunit beta, putative Get druggable targets OG5_128081 All targets in OG5_128081
Plasmodium vivax conserved Plasmodium protein, unknown function Get druggable targets OG5_128081 All targets in OG5_128081
Trypanosoma cruzi protein farnesyltransferase, putative Get druggable targets OG5_128081 All targets in OG5_128081
Trypanosoma brucei gambiense protein farnesyltransferase beta subunit, putative Get druggable targets OG5_128081 All targets in OG5_128081
Toxoplasma gondii prenyltransferase and squalene oxidase repeat-containing protein Get druggable targets OG5_128081 All targets in OG5_128081
Leishmania infantum farnesyltransferase beta subunit Get druggable targets OG5_128081 All targets in OG5_128081
Entamoeba histolytica protein farnesyltransferase beta subunit, putative Get druggable targets OG5_128081 All targets in OG5_128081
Leishmania braziliensis farnesyltransferase beta subunit Get druggable targets OG5_128081 All targets in OG5_128081
Candida albicans similar to S. cerevisiae RAM1 (YDL090C) beta subunit of farnesyl transferase (Ram1p+Ram2p), involved in prenylation of RAS prote Get druggable targets OG5_128081 All targets in OG5_128081
Schistosoma japonicum ko:K05954 farnesyltransferase, CAAX box, beta [EC:2.5.1.58], putative Get druggable targets OG5_128081 All targets in OG5_128081
Plasmodium knowlesi conserved Plasmodium protein, unknown function Get druggable targets OG5_128081 All targets in OG5_128081
Cryptosporidium hominis chain B, structure of fpt bound to ggpp Get druggable targets OG5_128081 All targets in OG5_128081
Leishmania major farnesyltransferase beta subunit Get druggable targets OG5_128081 All targets in OG5_128081
Trichomonas vaginalis geranylgeranyl transferase type I beta subunit, putative Get druggable targets OG5_128081 All targets in OG5_128081
Brugia malayi Prenyltransferase and squalene oxidase repeat family protein Get druggable targets OG5_128081 All targets in OG5_128081
Plasmodium vivax farnesyltransferase beta subunit, putative Get druggable targets OG5_128081 All targets in OG5_128081
Neospora caninum protein farnesyltranstransferase beta subunit, putative Get druggable targets OG5_128081 All targets in OG5_128081
Trichomonas vaginalis type I geranylgeranyltransferase beta subunit, putative Get druggable targets OG5_128081 All targets in OG5_128081
Leishmania mexicana farnesyltransferase beta subunit Get druggable targets OG5_128081 All targets in OG5_128081
Trypanosoma brucei protein farnesyltransferase beta subunit Get druggable targets OG5_128081 All targets in OG5_128081
Leishmania donovani farnesyltransferase beta subunit Get druggable targets OG5_128081 All targets in OG5_128081
Babesia bovis prenyltransferase and squalene oxidase repeat family protein Get druggable targets OG5_128081 All targets in OG5_128081
Candida albicans similar to S. cerevisiae RAM1 (YDL090C) beta subunit of farnesyl transferase (Ram1p+Ram2p), involved in prenylation of RAS prote Get druggable targets OG5_128081 All targets in OG5_128081
Echinococcus multilocularis protein farnesyltransferase subunit beta Get druggable targets OG5_128081 All targets in OG5_128081
Echinococcus granulosus protein farnesyltransferase subunit beta Get druggable targets OG5_128081 All targets in OG5_128081
Loa Loa (eye worm) prenyltransferase and squalene oxidase repeat family protein Get druggable targets OG5_128081 All targets in OG5_128081

By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity

Obtained from network model

Ranking Plot


Putative Targets List


Species Potential target Raw Global Species
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0032 0.0512
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0032 0.0512
Echinococcus granulosus thioredoxin glutathione reductase 0.0047 0.019 0.0781
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0057 0.0245 0.1666
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0033 0.0113 0.04
Echinococcus multilocularis phospholipid transporting ATPase IIB 0.0015 0.0017 0.0035
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0051 0.021 0.1739
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.0033 0.0113 0.0466
Echinococcus granulosus nervana 2 0.0194 0.098 0.4059
Schistosoma mansoni bromodomain containing protein 0.0064 0.028 0.1158
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0018 0.0036 0.0639
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0082 0.2037
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0032 0.0512
Trypanosoma cruzi phospholipid-transporting ATPase 1-like protein, putative 0.0016 0.0022 0.0095
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0016 0.0025 0.0157
Brugia malayi Sodium/potassium-transporting ATPase alpha chain, putative 0.0165 0.0825 0.6832
Brugia malayi CXXC zinc finger family protein 0.0032 0.0111 0.0916
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0022 0.0057 0.0802
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0024 0.0066 0.0357
Echinococcus multilocularis dual 3',5' cyclic AMP and GMP phosphodiesterase 0.0033 0.0113 0.0264
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0018 0.0032 0.0266
Plasmodium falciparum glutathione reductase 0.0047 0.019 0.5277
Trypanosoma brucei 3', 5'-cyclic nucleotide phosphodiesterase, putative 0.0033 0.0113 0.1931
Brugia malayi Glutathione S-transferase 4 0.002 0.0043 0.0354
Schistosoma mansoni phospholipid-transporting atpase 0.0016 0.0022 0.0087
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0012 0.0001 0.0011
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0033 0.0113 0.2962
Loa Loa (eye worm) hypothetical protein 0.0025 0.0072 0.0401
Trypanosoma cruzi DNA polymerase eta, putative 0.0068 0.0302 0.5733
Entamoeba histolytica phospholipid-transporting P-type ATPase, putative 0.0016 0.0022 0.0144
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0022 0.0057 0.0292
Brugia malayi haloacid dehalogenase-like hydrolase family protein 0.0041 0.0158 0.131
Echinococcus multilocularis calcium transporting atpase 0.007 0.0315 0.0745
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0035 0.0126 0.0295
Trichomonas vaginalis cAMP and cAMP-inhibited cGMP 3,5-cyclic phosphodiesterase, putative 0.0033 0.0113 0.2962
Trypanosoma brucei hypothetical protein, conserved 0.0018 0.0032 0.0312
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0068 0.1589
Leishmania major P-type H -ATPase, putative 0.004 0.0154 0.2766
Plasmodium vivax cyclic nucleotide phosphodiesterase, putative 0.0033 0.0113 0.2924
Schistosoma mansoni DNA polymerase IV / kappa 0.0018 0.0032 0.0131
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0033 0.0113 0.2962
Trypanosoma brucei lanosterol synthase 0.0074 0.0335 0.6387
Loa Loa (eye worm) hypothetical protein 0.002 0.0043 0.019
Trypanosoma cruzi hypothetical protein, conserved 0.0018 0.0032 0.0312
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0018 0.0032 0.0124
Schistosoma mansoni retinoic acid receptor RXR 0.0051 0.021 0.0868
Echinococcus multilocularis calcium:calmodulin dependent 3',5' cyclic 0.0033 0.0113 0.0264
Mycobacterium tuberculosis Probable reductase 0.0107 0.0515 0.0697
Trypanosoma cruzi hypothetical protein, conserved 0.0018 0.0032 0.0312
Schistosoma mansoni chromobox protein 0.0068 0.0304 0.1257
Trypanosoma cruzi DNA polymerase kappa, putative 0.0057 0.0245 0.4578
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0021 0.0049 0.0652
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0051 0.021 0.1739
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0033 0.0113 0.1931
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0149 0.2658
Trypanosoma cruzi hypothetical protein, conserved 0.0033 0.0113 0.1931
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0051 0.021 0.0862
Trypanosoma brucei calcium motive p-type ATPase, putative 0.007 0.0315 0.5997
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0033 0.0113 0.2962
Trichomonas vaginalis r2r3-MYB transcription factor, putative 0.0028 0.0086 0.2135
Toxoplasma gondii thioredoxin reductase 0.0047 0.019 0.0679
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.0236 0.1207 0.5003
Leishmania major trypanothione reductase 0.0047 0.019 0.3486
Trichomonas vaginalis cation-transporting ATPase, putative 0.0015 0.0017 0.0053
Schistosoma mansoni sodium/potassium-dependent atpase beta subunit 0.0234 0.1198 0.4966
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0032 0.0512
Trypanosoma cruzi hypothetical protein, conserved 0.0033 0.0113 0.1931
Brugia malayi Nuclear hormone receptor E75 0.0024 0.0066 0.0544
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0033 0.0113 0.2962
Mycobacterium tuberculosis Possible metal cation transporting P-type ATPase CtpH 0.0044 0.0173 0.0218
Echinococcus granulosus chromobox protein 1 0.0068 0.0304 0.1251
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0033 0.0113 0.04
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.0022 0.0057 0.1214
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0018 0.0032 0.013
Trypanosoma cruzi lanosterol synthase, putative 0.0074 0.0335 0.6387
Schistosoma mansoni geranylgeranyl transferase type II beta subunit 0.0018 0.0035 0.0143
Giardia lamblia Plasma membrane calcium-transporting ATPase 2 0.0064 0.028 0.1926
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.0033 0.0113 0.0466
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0024 0.0066 0.0151
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0082 0.2037
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.0036 0.0639
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0051 0.021 0.1739
Schistosoma mansoni sodium / potassium ATPase beta chain 0.0194 0.098 0.4062
Trichomonas vaginalis cAMP/cGMP cyclic nucleotide phosphodiesterase, putative 0.0033 0.0113 0.2962
Schistosoma mansoni zinc finger protein 0.0024 0.0066 0.027
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0033 0.0113 0.2962
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0033 0.0113 0.2962
Brugia malayi Bloom's syndrome protein homolog 0.0022 0.0057 0.047
Trypanosoma brucei hypothetical protein, conserved 0.0025 0.0072 0.11
Trichomonas vaginalis DNA helicase recq, putative 0.0022 0.0057 0.126
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0024 0.0066 0.0151
Brugia malayi Bromodomain containing protein 0.0037 0.0138 0.1147
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0022 0.0057 0.0227
Entamoeba histolytica recQ family helicase, putative 0.0022 0.0057 0.1214
Plasmodium vivax prenyltransferase alpha subunit, putative 0.0025 0.0072 0.1665
Trypanosoma cruzi cAMP phosphodiesterase A, putative 0.0033 0.0113 0.1931
Trypanosoma brucei phospholipid-translocating ATPase, putative 0.0016 0.0022 0.0095
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0068 0.0305 0.1264
Trichomonas vaginalis r2r3-MYB transcription factor, putative 0.0027 0.0085 0.2113
Loa Loa (eye worm) hypothetical protein 0.0069 0.0309 0.2138
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0051 0.021 0.0868
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0016 0.0025 0.0237
Loa Loa (eye worm) hypothetical protein 0.0051 0.021 0.1413
Trypanosoma brucei DNA polymerase kappa, putative 0.0057 0.0245 0.4578
Giardia lamblia Rab geranylgeranyltransferase 0.0025 0.0072 0.04
Loa Loa (eye worm) hypothetical protein 0.0024 0.0066 0.0357
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0047 0.019 0.0243
Schistosoma mansoni nuclear receptor 0.0024 0.0066 0.027
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0024 0.0065 0.0151
Loa Loa (eye worm) hypothetical protein 0.0234 0.1198 0.8641
Loa Loa (eye worm) nuclear hormone receptor 0.0024 0.0066 0.0357
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0018 0.0032 0.0305
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0149 0.2658
Trichomonas vaginalis protein farnesyltransferase beta subunit, putative 0.0018 0.0035 0.0608
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0018 0.0032 0.0071
Trypanosoma brucei cAMP-specific phosphodiesterase 0.0033 0.0113 0.1931
Entamoeba histolytica phospholipid-transporting P-type ATPase, putative 0.0021 0.0052 0.1066
Trypanosoma cruzi ISWI complex protein 0.0015 0.0017 0.001
Loa Loa (eye worm) sodium potassium adenosine triphosphatase 0.0035 0.0124 0.0785
Trypanosoma cruzi DNA polymerase kappa, putative 0.0057 0.0245 0.4578
Entamoeba histolytica Rab geranylgeranyltransferase beta subunit, putative 0.0018 0.0035 0.0558
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0033 0.0113 0.04
Plasmodium vivax glutathione S-transferase, putative 0.0025 0.0074 0.1745
Trypanosoma cruzi DNA damage repair protein, putative 0.0018 0.0032 0.0312
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0033 0.0113 0.04
Brugia malayi Probable cation-transporting ATPase C10C6.6 in chromosome IV 0.0015 0.0017 0.014
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0051 0.021 0.1413
Trichomonas vaginalis calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0033 0.0113 0.2962
Loa Loa (eye worm) hypothetical protein 0.0035 0.0124 0.0785
Echinococcus granulosus calcium:calmodulin dependent 3'5' cyclic 0.0033 0.0113 0.046
Plasmodium falciparum glutathione reductase 0.0016 0.0025 0.0237
Wolbachia endosymbiont of Brugia malayi UDP-N-acetylglucosamine 1-carboxyvinyltransferase 0.1867 1 1
Giardia lamblia Hypothetical protein 0.0033 0.0113 0.0703
Brugia malayi conserved hypotetical protein 0.0024 0.0066 0.0544
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0033 0.0113 0.04
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0089 0.0417 0.2926
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0033 0.0113 0.04
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0051 0.021 0.1739
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0033 0.0113 0.2962
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0051 0.021 0.1739
Echinococcus multilocularis thyroid hormone receptor alpha 0.0051 0.021 0.0494
Echinococcus multilocularis nervana 2 0.0234 0.1198 0.2845
Trichomonas vaginalis mercuric reductase, putative 0.0016 0.0025 0.0289
Loa Loa (eye worm) hypothetical protein 0.0024 0.0066 0.0357
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0022 0.0057 0.0197
Loa Loa (eye worm) hypothetical protein 0.0022 0.0057 0.0292
Trichomonas vaginalis cGMP-inhibited 3,5-cyclic phosphodiesterase, putative 0.0033 0.0113 0.2962
Trypanosoma brucei DNA polymerase kappa, putative 0.0057 0.0245 0.4578
Echinococcus multilocularis cation transporting ATPase 13A1 0.0015 0.0017 0.0035
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0051 0.021 0.1413
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0113 0.2962
Schistosoma mansoni coup transcription factor 0.0051 0.021 0.0868
Schistosoma mansoni DNA helicase recq5 0.0022 0.0057 0.0233
Trypanosoma cruzi calcium-translocating P-type ATPase, putative 0.0035 0.0124 0.2157
Brugia malayi Bromodomain containing protein 0.0075 0.0342 0.2829
Leishmania major DNA polymerase eta, putative 0.0068 0.0302 0.5733
Echinococcus granulosus cation transporting ATPase 13A3 0.0015 0.0017 0.0061
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0015 0.0018 0.0087
Echinococcus granulosus cation transporting ATPase 13A1 0.0015 0.0017 0.0061
Echinococcus granulosus fetal alzheimer antigen falz 0.0024 0.0065 0.0263
Toxoplasma gondii heavy metal translocating P-type ATPase subfamily protein 0.0015 0.0017 0.0053
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0057 0.0245 0.4578
Echinococcus granulosus sodium:potassium transporting ATPase subunit 0.0234 0.1198 0.4963
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0033 0.0113 0.2962
Loa Loa (eye worm) hypothetical protein 0.0033 0.0113 0.0703
Loa Loa (eye worm) glutathione reductase 0.0047 0.019 0.1269
Echinococcus granulosus protein prenyltransferase alpha subunit 0.0025 0.0072 0.0288
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0051 0.021 0.0862
Echinococcus granulosus glutathione s transferase mu 0.0025 0.0074 0.0299
Brugia malayi polk-prov protein 0.0018 0.0032 0.0268
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0033 0.0113 0.2962
Echinococcus multilocularis dna polymerase eta 0.0107 0.0514 0.1218
Mycobacterium ulcerans hypothetical protein 0.0018 0.0032 0.0016
Echinococcus multilocularis sodium:potassium dependent atpase beta subunit 0.0194 0.098 0.2326
Brugia malayi hypothetical protein 0.0012 0.0002 0.0018
Trypanosoma cruzi hypothetical protein, conserved 0.0033 0.0113 0.1931
Trypanosoma brucei Protein prenyltransferase alpha subunit repeat, putative 0.0025 0.0072 0.11
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0149 0.2658
Entamoeba histolytica phospholipid-transporting ATPase Neo1, putative 0.0016 0.0022 0.0144
Loa Loa (eye worm) PDE1B protein 0.0033 0.0113 0.0703
Trichomonas vaginalis phospholipid-transporting ATPase, putative 0.0016 0.0022 0.0196
Echinococcus granulosus Nuclear hormone receptor HR96 0.0024 0.0066 0.0264
Trypanosoma cruzi calcium motive p-type ATPase, putative 0.007 0.0315 0.5997
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0051 0.021 0.0494
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0018 0.0032 0.0309
Leishmania major cAMP phosphodiesterase A, putative;with=GeneDB:LinJ18_V3.1100 0.0033 0.0113 0.1931
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0032 0.0512
Leishmania major DNA polymerase kappa, putative 0.0018 0.0032 0.0312
Trichomonas vaginalis phospholipid-transporting ATPase, putative 0.0015 0.0017 0.0053
Trichomonas vaginalis protein farnesyltransferase alpha subunit, putative 0.0025 0.0072 0.1709
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0024 0.0066 0.027
Schistosoma mansoni type V p-type atpase isoform 0.0015 0.0017 0.0067
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0033 0.0113 0.04
Trichomonas vaginalis protein farnesyltransferase alpha subunit, putative 0.0025 0.0072 0.1709
Trichomonas vaginalis cation-transporting ATPase, putative 0.0069 0.031 0.894
Schistosoma mansoni ataxia telangiectasia mutated (atm) 0.0024 0.0068 0.0278
Plasmodium vivax P-type ATPase4, putative 0.0076 0.0345 1
Trypanosoma cruzi DNA polymerase eta, putative 0.0107 0.0514 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0032 0.0512
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0027 0.0081 0.0188
Loa Loa (eye worm) hypothetical protein 0.0186 0.0941 0.676
Echinococcus granulosus dna polymerase eta 0.0107 0.0514 0.2126
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0016 0.0025 0.0157
Trichomonas vaginalis cation-transporting ATPase, putative 0.0069 0.031 0.894
Echinococcus granulosus glutathione S transferase Mu 1 0.0025 0.0074 0.0299
Loa Loa (eye worm) CXXC zinc finger family protein 0.0032 0.0111 0.0686
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0051 0.021 0.1739
Entamoeba histolytica plasma membrane calcium ion-transporting ATPase, putative 0.0041 0.0158 0.43
Entamoeba histolytica myb-like DNA-binding domain containing protein 0.0027 0.0085 0.2071
Brugia malayi Probable 3',5'-cyclic phosphodiesterase R153.1, putative 0.0236 0.1207 1
Schistosoma mansoni hypothetical protein 0.0169 0.0845 0.3503
Plasmodium vivax protein prenyltransferase alpha subunit, putative 0.0025 0.0072 0.1665
Trypanosoma brucei DNA polymerase eta, putative 0.0107 0.0514 1
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.0268 0.1383 0.5734
Echinococcus granulosus glutathione S transferase 0.0025 0.0074 0.0299
Giardia lamblia Sgs1 DNA helicase, putative 0.0022 0.0057 0.0292
Trypanosoma brucei cAMP-specific phosphodiesterase, putative 0.0033 0.0113 0.1931
Loa Loa (eye worm) hypothetical protein 0.0051 0.021 0.1413
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0015 0.0017 0.0061
Schistosoma mansoni hypothetical protein 0.0035 0.0126 0.0521
Plasmodium vivax thioredoxin reductase, putative 0.0047 0.019 0.5277
Trypanosoma cruzi P-type H+-ATPase, putative 0.0035 0.0124 0.2157
Trypanosoma brucei cAMP-specific phosphodiesterase 0.0033 0.0113 0.1931
Trichomonas vaginalis C-MYB, putative 0.0027 0.0085 0.2113
Brugia malayi Protein prenyltransferase alpha subunit repeat containing protein 0.0025 0.0072 0.0593
Entamoeba histolytica Plasma membrane calcium-transporting ATPase, putative 0.0069 0.031 0.8934
Brugia malayi phospholipid-translocating P-type ATPase, flippase family protein 0.0016 0.0022 0.0179
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.0036 0.0639
Loa Loa (eye worm) hypothetical protein 0.0045 0.0178 0.1176
Trichomonas vaginalis DNA polymerase eta, putative 0.0057 0.0245 0.6947
Schistosoma mansoni nuclear hormone receptor 0.0024 0.0066 0.027
Trypanosoma cruzi lanosterol synthase, putative 0.0074 0.0335 0.6387
Mycobacterium ulcerans 3-phosphoshikimate 1-carboxyvinyltransferase 0.0526 0.2774 0.2762
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0113 0.2962
Echinococcus multilocularis sarco:endoplasmic reticulum calcium ATPase 0.0069 0.031 0.0733
Schistosoma mansoni calcium-transporting atpase sarcoplasmic/endoplasmic reticulum type (calcium pump) 0.007 0.0315 0.1305
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0018 0.0032 0.0305
Brugia malayi nuclear hormone receptor family member nhr-6 0.0024 0.0066 0.0544
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0051 0.021 0.0862
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0051 0.021 0.1748
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0051 0.021 0.0868
Trypanosoma cruzi P-type H+-ATPase, putative 0.004 0.0154 0.2766
Trypanosoma brucei vacuolar-type Ca2+-ATPase 1 0.0069 0.031 0.5902
Echinococcus multilocularis zinc finger protein 0.0021 0.005 0.0113
Schistosoma mansoni chromobox protein 0.0068 0.0304 0.1257
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0017 0.003 0.0123
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0024 0.0066 0.027
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0033 0.0113 0.0936
Trypanosoma brucei DNA polymerase kappa, putative 0.0018 0.0032 0.0312
Trypanosoma brucei cAMP phosphodiesterase A, putative 0.0033 0.0113 0.1931
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0018 0.0032 0.0305
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0033 0.0113 0.04
Loa Loa (eye worm) hypothetical protein 0.0018 0.0035 0.0134
Schistosoma mansoni Na+/K+ transporting ATPase subunit alpha 0.019 0.0962 0.399
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0016 0.0025 0.0008
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0018 0.0032 0.0305
Mycobacterium ulcerans DNA polymerase IV 0.0057 0.0245 0.0228
Plasmodium falciparum geranylgeranyl transferase type2 beta subunit, putative 0.0018 0.0035 0.0558
Echinococcus multilocularis glutathione S transferase 0.0025 0.0074 0.0171
Toxoplasma gondii hypothetical protein 0.0025 0.0072 0.025
Toxoplasma gondii prenyltransferase and squalene oxidase repeat-containing protein 0.0018 0.0035 0.0119
Entamoeba histolytica geranylgeranyl transferase beta subunit 0.0018 0.0035 0.0558
Schistosoma mansoni plasma membrane calcium-transporting atpase 0.007 0.0315 0.1305
Onchocerca volvulus 0.0194 0.098 0.8179
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0033 0.0113 0.04
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0022 0.0057 0.013
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0018 0.0032 0.0071
Schistosoma mansoni steroid hormone receptor ad4bp 0.0051 0.021 0.0868
Echinococcus granulosus geranylgeranyl transferase type 2 subunit alpha 0.0025 0.0072 0.0288
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0024 0.0065 0.0269
Loa Loa (eye worm) hypothetical protein 0.0027 0.0081 0.047
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0038 0.0142 0.1184
Trypanosoma brucei unspecified product 0.0039 0.0149 0.2658
Trypanosoma cruzi hypothetical protein, conserved 0.0025 0.0072 0.11
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.0236 0.1207 0.2868
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0017 0.0027 0.0058
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0018 0.0036 0.0639
Echinococcus granulosus cAMP and cAMP inhibited cGMP 3'5' cyclic 0.0033 0.0113 0.046
Echinococcus multilocularis nervana 2 0.0194 0.098 0.2326
Toxoplasma gondii NADPH-glutathione reductase 0.0016 0.0025 0.0081
Echinococcus granulosus ecdysone induced protein 78C 0.0051 0.021 0.0862
Echinococcus granulosus dnaJ subfamily B 0.0459 0.2411 1
Trypanosoma brucei DNA polymerase kappa, putative 0.0057 0.0245 0.4578
Mycobacterium ulcerans metal cation-transporting p-type ATPase F, CtpF 0.0076 0.0345 0.0329
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0022 0.0057 0.1214
Echinococcus multilocularis Ca2+ transporting ATPase plasma membrane 0.007 0.0315 0.0745
Echinococcus granulosus calcium:calmodulin dependent 3'5' cyclic 0.0033 0.0113 0.046
Entamoeba histolytica hypothetical protein 0.0035 0.0126 0.3328
Echinococcus granulosus prostaglandin H2 D isomerase 0.0025 0.0074 0.0299
Schistosoma mansoni camp-specific cyclic nucleotide phosphodiesterase 0.0033 0.0113 0.0466
Loa Loa (eye worm) hypothetical protein 0.0024 0.0066 0.0357
Echinococcus multilocularis thioredoxin glutathione reductase 0.0047 0.019 0.0448
Mycobacterium tuberculosis Halimadienyl diphosphate synthase 0.0074 0.0335 0.0445
Trichomonas vaginalis ATPase, class VI, type 11C, putative 0.0016 0.0022 0.0196
Schistosoma mansoni protein farnesyltransferase subunit beta 0.0067 0.0299 0.1239
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0025 0.0157
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.0036 0.0639
Loa Loa (eye worm) Na,K-ATPase alpha subunit 0.019 0.0962 0.6919
Echinococcus granulosus sodium:potassium dependent atpase beta subunit 0.0234 0.1198 0.4963
Entamoeba histolytica hypothetical protein 0.0035 0.0126 0.3328
Loa Loa (eye worm) transcription factor SMAD2 0.0119 0.0577 0.4096
Giardia lamblia Myb 1-like protein 0.0028 0.0086 0.0503
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0022 0.0057 0.0802
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0051 0.021 0.0862
Loa Loa (eye worm) hypothetical protein 0.0051 0.021 0.1413
Echinococcus multilocularis bloom syndrome protein 0.0022 0.0057 0.013
Trypanosoma cruzi protein farnesyltransferase, putative 0.0067 0.0299 0.5679
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0032 0.0512
Trypanosoma cruzi DNA damage repair protein, putative 0.0018 0.0032 0.0312
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0033 0.0113 0.2962
Leishmania major hypothetical protein, conserved 0.0033 0.0113 0.1931
Echinococcus granulosus cpg binding protein 0.0036 0.0131 0.0533
Plasmodium falciparum geranylgeranyl transferase type-2 subunit alpha, putative 0.0025 0.0072 0.1665
Giardia lamblia hypothetical protein 0.0033 0.0113 0.0703
Echinococcus granulosus calcium transporting atpase 0.007 0.0315 0.1299
Loa Loa (eye worm) hypothetical protein 0.0234 0.1198 0.8641
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0022 0.0057 0.047
Trichomonas vaginalis cation-transporting ATPase, putative 0.0016 0.0022 0.0196
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0032 0.0512
Echinococcus multilocularis Rab geranylgeranyltransferase, beta subunit 0.0018 0.0035 0.0079
Plasmodium falciparum thioredoxin reductase 0.0016 0.0025 0.0237
Brugia malayi hypothetical protein 0.0027 0.0081 0.0672
Plasmodium falciparum 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0033 0.0113 0.2924
Schistosoma mansoni cation-transporting atpase worm 0.0015 0.0017 0.0067
Trypanosoma cruzi phospholipid-transporting ATPase 1-like protein, putative 0.0016 0.0022 0.0095
Loa Loa (eye worm) hypothetical protein 0.0107 0.0514 0.364
Toxoplasma gondii target of rapamycin (TOR), putative 0.0018 0.0032 0.0108
Loa Loa (eye worm) hypothetical protein 0.0268 0.1383 1
Loa Loa (eye worm) hypothetical protein 0.0018 0.0032 0.0114
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0025 0.0157
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0033 0.0113 0.2962
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0033 0.0113 0.04
Loa Loa (eye worm) hypothetical protein 0.0069 0.031 0.2148
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.0268 0.1383 0.3287
Echinococcus multilocularis cation transporting ATPase 13A3 0.0015 0.0017 0.0035
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0051 0.021 0.1413
Mycobacterium ulcerans DNA polymerase IV 0.0057 0.0245 0.0228
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0033 0.0113 0.2962
Leishmania major lanosterol synthase, putative 0.0056 0.0236 0.441
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0268 0.1383 0.4984
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0018 0.0032 0.0462
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0082 0.0379 0.1571
Toxoplasma gondii calcium-translocating P-type ATPase, PMCA-type protein 0.0069 0.031 0.1112
Schistosoma mansoni na+/k+ atpase alpha subunit 0.0185 0.0932 0.3864
Loa Loa (eye worm) hypothetical protein 0.0051 0.021 0.1413
Plasmodium vivax 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0033 0.0113 0.2924
Brugia malayi Probable 3',5'-cyclic phosphodiesterase R153.1, putative 0.0033 0.0113 0.0936
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0032 0.0512
Plasmodium falciparum phospholipid-transporting ATPase, putative 0.0016 0.0022 0.0144
Brugia malayi hypothetical protein 0.0024 0.0066 0.0544
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0032 0.0512
Loa Loa (eye worm) prenyltransferase alpha subunit repeat containing protein 0.0025 0.0072 0.0401
Brugia malayi Probable 3',5'-cyclic phosphodiesterase T04D3.3, putative 0.0033 0.0113 0.0936
Trypanosoma brucei vacuolar-type Ca2+-ATPase 2 0.0069 0.031 0.5902
Trypanosoma brucei DNA polymerase IV, putative 0.0057 0.0245 0.4578
Trichomonas vaginalis geranylgeranyl transferase type II beta subunit, putative 0.0067 0.0299 0.8605
Echinococcus granulosus zinc finger protein 0.0021 0.005 0.0198
Loa Loa (eye worm) transbilayer Amphipath transporters family member 0.0016 0.0022 0.0035
Plasmodium vivax geranylgeranyltransferase, putative 0.0018 0.0035 0.0558
Loa Loa (eye worm) hypothetical protein 0.0024 0.0066 0.0357
Trichomonas vaginalis r2r3-MYB transcription factor, putative 0.0027 0.0085 0.2113
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0033 0.0113 0.0466
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0018 0.0032 0.0305
Echinococcus multilocularis geminin 0.0169 0.0845 0.2005
Trypanosoma brucei DNA polymerase kappa, putative 0.0018 0.0032 0.0312
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0057 0.0245 0.1006
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0018 0.0032 0.0266
Trichomonas vaginalis MYB72, putative 0.0027 0.0085 0.2113
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0016 0.0025 0.0157
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0033 0.0113 0.2962
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.0268 0.1383 0.3287
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0032 0.0512
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.0069 0.031 0.894
Trichomonas vaginalis MYB, putative 0.0028 0.0086 0.2135
Onchocerca volvulus 0.0024 0.0066 0.0543
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0089 0.0417 0.3451
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0033 0.0113 0.2962
Chlamydia trachomatis phosphoshikimate 1-carboxyl vinyltransferase 0.0526 0.2774 0.2762
Entamoeba histolytica myb-like DNA-binding domain containing protein 0.0027 0.0085 0.2071
Echinococcus multilocularis glutathione s transferase mu 0.0025 0.0074 0.0171
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0033 0.0113 0.0466
Entamoeba histolytica protein farnesyltransferase beta subunit, putative 0.0067 0.0299 0.8598
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0033 0.0113 0.0936
Trichomonas vaginalis cation-transporting ATPase, putative 0.0069 0.031 0.894
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.0069 0.031 0.894
Loa Loa (eye worm) hypothetical protein 0.0038 0.0142 0.0919
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0022 0.0057 0.047
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0051 0.021 0.1739
Trypanosoma cruzi DNA polymerase kappa, putative 0.0057 0.0245 0.4578
Trypanosoma brucei unspecified product 0.0039 0.0149 0.2658
Leishmania major DNA damage repair protein, putative 0.0018 0.0032 0.0312
Brugia malayi Prenyltransferase and squalene oxidase repeat family protein 0.0067 0.0299 0.2479
Onchocerca volvulus 0.0024 0.0066 0.0543
Echinococcus multilocularis sodium:potassium transporting ATPase subunit 0.0234 0.1198 0.2845
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0051 0.021 0.0862
Echinococcus granulosus histone lysine methyltransferase setb 0.0017 0.003 0.0117
Onchocerca volvulus 0.003 0.0098 0.0813
Trichomonas vaginalis pc-MYB2, putative 0.0027 0.0085 0.2113
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0089 0.0417 0.0986
Schistosoma mansoni nuclear receptor 0.0024 0.0066 0.027
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0068 0.0302 0.1082
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0016 0.0025 0.01
Schistosoma mansoni terminal deoxycytidyl transferase 0.0057 0.0245 0.1012
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0032 0.0512
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0051 0.021 0.1739
Echinococcus granulosus FTZ F1 alpha 0.0051 0.021 0.0862
Loa Loa (eye worm) MH2 domain-containing protein 0.0119 0.0577 0.4096
Toxoplasma gondii sarco/endoplasmic reticulum Ca2+-ATPase 0.0076 0.0345 0.1238
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0033 0.0113 0.04
Trypanosoma brucei calcium-translocating P-type ATPase 0.007 0.0315 0.5997
Trichomonas vaginalis cation-transporting ATPase fungi, putative 0.0069 0.031 0.894
Trichomonas vaginalis DNA helicase recq1, putative 0.0022 0.0057 0.126
Trypanosoma cruzi ISWI complex protein 0.0015 0.0017 0.001
Leishmania major P-type ATPase, putative 0.007 0.0315 0.5997
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0051 0.021 0.1739
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0015 0.0017 0.0067
Trypanosoma cruzi protein farnesyltransferase, putative 0.0067 0.0299 0.5679
Loa Loa (eye worm) hypothetical protein 0.0024 0.0066 0.0357
Echinococcus multilocularis cpg binding protein 0.0036 0.0131 0.0305
Trypanosoma cruzi plasma-membrane proton-efflux P-type ATPase, putative 0.0035 0.0124 0.2157
Loa Loa (eye worm) prenyltransferase and squalene oxidase repeat family protein 0.0067 0.0299 0.2067
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0032 0.0512
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0033 0.0113 0.2962
Trypanosoma cruzi cAMP-specific phosphodiesterase, putative 0.0033 0.0113 0.1931
Mycobacterium ulcerans cation-transporter ATPase I CtpI 0.0044 0.0173 0.0156
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0015 0.0017 0.0035
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0119 0.0579 0.0787
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0033 0.0113 0.0466
Plasmodium falciparum thioredoxin reductase 0.0047 0.019 0.5277
Echinococcus granulosus plasma membrane calcium transporting ATPase 0.007 0.0315 0.1299
Brugia malayi glutathione reductase 0.0047 0.019 0.1576
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0119 0.0579 0.0787
Loa Loa (eye worm) hypothetical protein 0.0024 0.0066 0.0357
Onchocerca volvulus 0.0051 0.021 0.1748
Echinococcus granulosus bloom syndrome protein 0.0022 0.0057 0.0227
Brugia malayi Thioredoxin reductase 0.0047 0.019 0.1576
Echinococcus granulosus sarco:endoplasmic reticulum calcium ATPase 0.0069 0.031 0.128
Brugia malayi nuclear hormone receptor 0.0051 0.021 0.1739
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0089 0.0417 0.1726
Trypanosoma brucei P-type H+-ATPase, putative 0.004 0.0154 0.2766
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0033 0.0113 0.04
Echinococcus granulosus nuclear receptor nhr 48 0.0024 0.0066 0.0264
Trypanosoma cruzi cAMP phosphodiesterase A, putative 0.0033 0.0113 0.1931
Echinococcus multilocularis dnaJ subfamily B 0.0459 0.2411 0.5732
Schistosoma mansoni hypothetical protein 0.0169 0.0845 0.3503
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0033 0.0113 0.2962
Leishmania major calcium-translocating P-type ATPase 0.0069 0.031 0.5902
Schistosoma mansoni sodium/potassium-dependent atpase beta subunit 0.0194 0.098 0.4062
Trichomonas vaginalis chromobox protein, putative 0.0041 0.0158 0.4326
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0033 0.0113 0.1931
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0142 0.3854
Leishmania major vacuolar-type Ca2 -ATPase, putative 0.0069 0.031 0.5902
Plasmodium falciparum phosphodiesterase delta, putative 0.0033 0.0113 0.2924
Onchocerca volvulus 0.0234 0.1198 1
Onchocerca volvulus 0.0184 0.0927 0.7741
Leishmania major phospholipid-transporting ATPase 1-like protein 0.0016 0.0022 0.0095
Trypanosoma cruzi plasma membrane Ca2+ ATPase 0.0069 0.031 0.5902
Trypanosoma cruzi P-type H+-ATPase, putative 0.004 0.0154 0.2766
Loa Loa (eye worm) hypothetical protein 0.0033 0.0113 0.0703
Entamoeba histolytica plasma membrane calcium-transporting ATPase 1, putative 0.0035 0.0123 0.3234
Trichomonas vaginalis glutathione reductase, putative 0.0016 0.0025 0.0289
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0016 0.0025 0.0237
Echinococcus granulosus phospholipid transporting atpase ih 0.0016 0.0022 0.0081
Entamoeba histolytica Plasma membrane calcium-transporting ATPase, putative 0.0069 0.031 0.8934
Echinococcus granulosus copper transporting ATPase 1 0.0015 0.0017 0.0061
Echinococcus multilocularis calcium:calmodulin dependent 3',5' cyclic 0.0033 0.0113 0.0264
Trypanosoma brucei calcium-transporting ATPase, putative 0.0045 0.0178 0.3231
Trypanosoma cruzi hypothetical protein, conserved 0.0033 0.0113 0.1931
Echinococcus granulosus geminin 0.0169 0.0845 0.3499
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0018 0.0032 0.0305
Giardia lamblia Prenyltransferase 0.0067 0.0299 0.2067
Brugia malayi E1-E2 ATPase family protein 0.0047 0.0189 0.1569
Brugia malayi ImpB/MucB/SamB family protein 0.0057 0.0245 0.2026
Mycobacterium leprae PROBABLE UDP-N-ACETYLGLUCOSAMINE 1-CARBOXYVINYLTRANSFERASE MURA 0.1341 0.7163 1
Trypanosoma cruzi calcium-translocating P-type ATPase, putative 0.0029 0.0093 0.1527
Schistosoma mansoni RAR-like nuclear receptor 0.0051 0.021 0.0868
Loa Loa (eye worm) hypothetical protein 0.0043 0.0171 0.113
Echinococcus multilocularis calcium transporting ATPase type 2C member 0.0076 0.0345 0.0817
Echinococcus multilocularis plasma membrane calcium transporting ATPase 0.007 0.0315 0.0745
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0051 0.021 0.0494
Schistosoma mansoni cation-transporting ATPase 0.0015 0.0017 0.0067
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0033 0.0113 0.04
Toxoplasma gondii histone lysine methyltransferase SET1 0.0063 0.0278 0.0997
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0051 0.021 0.0494
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0089 0.0417 0.1726
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0018 0.0032 0.0305
Trichomonas vaginalis chromobox protein, putative 0.0068 0.0304 0.8733
Toxoplasma gondii Rab geranylgeranyl transferase type II beta subunit, putative 0.0018 0.0035 0.0119
Trypanosoma brucei unspecified product 0.0057 0.0245 0.4578
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0057 0.0245 0.0319
Loa Loa (eye worm) hypothetical protein 0.0115 0.0554 0.393
Echinococcus granulosus phospholipid transporting ATPase IA 0.0016 0.0022 0.0081
Trichomonas vaginalis r2r3-MYB transcription factor, putative 0.0027 0.0085 0.2113
Brugia malayi chromobox protein homolog 3 0.0038 0.0142 0.118
Schistosoma mansoni phospholipid-transporting atpase 0.0016 0.0022 0.0087
Loa Loa (eye worm) hypothetical protein 0.0021 0.0049 0.0237
Brugia malayi hypothetical protein 0.0027 0.0081 0.0672
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0016 0.0025 0.0008
Leishmania major geranylgeranyltransferase, putative 0.0018 0.0035 0.0368
Entamoeba histolytica deoxycytidyl transferase, putative 0.0057 0.0245 0.6931
Leishmania major cAMP-specific phosphodiesterase, putative 0.0033 0.0113 0.1931
Schistosoma mansoni cpg binding protein 0.0032 0.0111 0.0456
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0033 0.0113 0.2962
Trichomonas vaginalis geranylgeranyl transferase type I beta subunit, putative 0.0018 0.0035 0.0608
Loa Loa (eye worm) sodium/potassium-transporting ATPase subunit alpha 0.0165 0.0825 0.5913
Toxoplasma gondii P-type ATPase PMA1 0.004 0.0154 0.0549
Leishmania major phosphatidylinositol kinase related protein, putative 0.0018 0.0032 0.0309
Trichomonas vaginalis ATPase, class VI, type 11C, putative 0.0015 0.0017 0.0053
Leishmania major hypothetical protein, conserved 0.0015 0.0017 0.001
Leishmania major calcium motive p-type ATPase, putative 0.007 0.0315 0.5997
Loa Loa (eye worm) hypothetical protein 0.0024 0.0066 0.0357
Loa Loa (eye worm) hypothetical protein 0.0027 0.0081 0.047
Loa Loa (eye worm) hypothetical protein 0.003 0.0098 0.0594
Giardia lamblia Phospholipid-transporting ATPase IIB, putative 0.0016 0.0022 0.0035
Loa Loa (eye worm) hypothetical protein 0.0024 0.0066 0.0357
Echinococcus granulosus thyroid hormone receptor alpha 0.0024 0.0066 0.0264
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0051 0.021 0.1739
Trichomonas vaginalis protein farnesyltransferase beta subunit, putative 0.0018 0.0035 0.0608
Echinococcus multilocularis ecdysone induced protein 78C 0.0051 0.021 0.0494
Entamoeba histolytica hypothetical protein 0.0024 0.0068 0.1544
Trypanosoma cruzi trypanothione reductase, putative 0.0016 0.0025 0.0157
Echinococcus multilocularis sodium:potassium dependent atpase beta subunit 0.0234 0.1198 0.2845
Entamoeba histolytica plasma membrane calcium ion-transporting ATPase, putative 0.0041 0.0159 0.4331
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0051 0.021 0.1413
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0033 0.0113 0.2962
Schistosoma mansoni thyroid hormone receptor 0.0051 0.021 0.0868
Loa Loa (eye worm) heterochromatin protein 1 0.0068 0.0304 0.2098
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0018 0.0032 0.0305
Brugia malayi tailless protein 0.0024 0.0066 0.0544
Plasmodium vivax glutathione reductase, putative 0.0047 0.019 0.5277
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.0268 0.1383 0.5734
Brugia malayi Nuclear hormone receptor-like 1 0.0051 0.021 0.1739
Plasmodium falciparum non-SERCA-type Ca2+ -transporting P-ATPase 0.0076 0.0345 1
Trypanosoma cruzi protein farnesyltransferase alpha subunit, putative 0.0025 0.0072 0.11
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0025 0.0157
Toxoplasma gondii P-type ATPase4, putative 0.0076 0.0345 0.1238
Mycobacterium leprae probable 3-phosphoshikimate 1-carboxyvinyl transferase AroA (5-ENOLPYRUVYLSHIKIMATE-3-PHOSPHATE SYNTHASE) (EPSP SYNTHASE) (EPSPS 0.0526 0.2774 0.3858
Loa Loa (eye worm) hypothetical protein 0.0017 0.003 0.0099
Echinococcus granulosus chromobox protein 1 0.0068 0.0304 0.1251
Loa Loa (eye worm) hypothetical protein 0.0051 0.021 0.1413
Brugia malayi SET domain containing protein 0.0012 0.0001 0.0006
Brugia malayi Nuclear hormone receptor E75 0.0024 0.0066 0.0544
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0051 0.021 0.0494
Schistosoma mansoni copper ABC transporter ATPase 0.0015 0.0017 0.0067
Plasmodium falciparum 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0033 0.0113 0.2924
Trichomonas vaginalis glutaminyl-tRNA synthetase, putative 0.002 0.0043 0.0837
Brugia malayi PHD-finger family protein 0.0026 0.0078 0.0645
Echinococcus multilocularis chromobox protein 1 0.0068 0.0304 0.0717
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0016 0.0025 0.0237
Brugia malayi hypothetical protein 0.0024 0.0066 0.0544
Schistosoma mansoni geranylgeranyl transferase type I beta subunit 0.0018 0.0035 0.0143
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0033 0.0113 0.2962
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.006 0.0261 0.0616
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0033 0.0113 0.0936
Entamoeba histolytica myb-like DNA-binding domain containing protein 0.0027 0.0085 0.2071
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.0018 0.0032 0.0109
Echinococcus multilocularis nervana 2 0.0234 0.1198 0.2845
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0107 0.0515 0.0697
Trypanosoma brucei DNA polymerase kappa, putative 0.0057 0.0245 0.4578
Trypanosoma cruzi plasma membrane Ca2+ ATPase 0.0069 0.031 0.5902
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0041 0.0158 0.1314
Giardia lamblia Plasma membrane calcium-transporting ATPase 2 0.0069 0.031 0.2148
Echinococcus multilocularis glutathione S transferase 0.0025 0.0074 0.0171
Giardia lamblia Phospholipid-transporting ATPase IIB, putative 0.0016 0.0022 0.0035
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0024 0.0068 0.102
Trypanosoma cruzi trypanothione reductase, putative 0.0047 0.019 0.3486
Onchocerca volvulus 0.0025 0.0072 0.0592
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0016 0.0025 0.0157
Trichomonas vaginalis cation-transporting ATPase, putative 0.0016 0.0022 0.0196
Schistosoma mansoni atpase class VI type 11c 0.0012 0.0002 0.0006
Trypanosoma brucei vacuolar-type Ca2+-ATPase, putative 0.0069 0.031 0.5902
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0051 0.021 0.1413
Echinococcus multilocularis nuclear receptor nhr 48 0.0024 0.0066 0.0151
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0018 0.0032 0.0305
Onchocerca volvulus 0.002 0.0043 0.0352
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.0069 0.031 0.894
Trypanosoma brucei DNA polymerase kappa, putative 0.0057 0.0245 0.4578
Echinococcus granulosus dna polymerase kappa 0.0057 0.0245 0.1006
Trichomonas vaginalis phospholipid-transporting ATPase, putative 0.0016 0.0022 0.0196
Trypanosoma brucei DNA damage repair protein, putative 0.0018 0.0032 0.0312
Schistosoma mansoni camp/cgmp cyclic nucleotide phosphodiesterase 0.0033 0.0113 0.0466
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0017 0.003 0.0067
Trichomonas vaginalis MYB3r3, putative 0.0027 0.0085 0.2113
Schistosoma mansoni cpg binding protein 0.0036 0.0131 0.0539
Giardia lamblia Rab geranylgeranyltransferase 0.0018 0.0035 0.0134
Entamoeba histolytica hypothetical protein 0.0035 0.0126 0.3328
Echinococcus multilocularis glutathione S-transferase 0.0025 0.0074 0.0171
Brugia malayi nuclear receptor NHR-88 0.0051 0.021 0.1739
Brugia malayi Probable 3',5'-cyclic phosphodiesterase C32E12.2, putative 0.0033 0.0113 0.0936
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0017 0.003 0.0123
Schistosoma mansoni cation-transporting atpase 13a1 (G-box binding protein) 0.0015 0.0017 0.0067
Brugia malayi Calcium-transporting ATPase sarcoplasmic/endoplasmic reticulum type 0.007 0.0315 0.261
Brugia malayi Probable protein farnesyltransferase beta subunit, putative 0.0018 0.0035 0.0292
Echinococcus granulosus phospholipid transporting ATPase IF 0.0016 0.0022 0.0081
Schistosoma mansoni methyl-cpg binding protein mbd 0.0017 0.0027 0.0108
Trypanosoma cruzi phospholipid-translocating ATPase, putative 0.0016 0.0022 0.0095
Echinococcus granulosus Nuclear hormone receptor HR96 0.0024 0.0066 0.0264
Trypanosoma cruzi hypothetical protein, conserved 0.0033 0.0113 0.1931
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0024 0.0068 0.056
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0018 0.0032 0.0305
Loa Loa (eye worm) hypothetical protein 0.0024 0.0066 0.0357
Trichomonas vaginalis cAMP and cAMP-inhibited cGMP 3,5-cyclic phosphodiesterase, putative 0.0033 0.0113 0.2962
Schistosoma mansoni hypothetical protein 0.0015 0.0017 0.0069
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0051 0.021 0.0868
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0032 0.0512
Loa Loa (eye worm) hypothetical protein 0.0129 0.0634 0.4515
Loa Loa (eye worm) hypothetical protein 0.004 0.0151 0.0984
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0016 0.0025 0.0011
Brugia malayi photoreceptor-specific nuclear receptor 0.0051 0.021 0.1739
Trypanosoma cruzi protein farnesyltransferase alpha subunit, putative 0.0025 0.0072 0.11
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0016 0.0025 0.0008
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0107 0.0515 0.0697
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0268 0.1383 0.5737
Schistosoma mansoni thyroid hormone receptor 0.0051 0.021 0.0868
Loa Loa (eye worm) hypothetical protein 0.019 0.0962 0.6919
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0051 0.021 0.1739
Brugia malayi Heterochromatin protein 1 0.0068 0.0304 0.2514
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0016 0.0025 0.0093
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0107 0.0515 0.0697
Echinococcus multilocularis geranylgeranyl transferase type 2 subunit alpha 0.0025 0.0072 0.0165
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0032 0.0512
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0033 0.0113 0.2962
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0033 0.0113 0.2962
Trypanosoma brucei 3', 5'-cyclic nucleotide phosphodiesterase, putative 0.0033 0.0113 0.1931
Echinococcus multilocularis high affinity cgmp specific 3' 5' cyclic 0.0033 0.0113 0.0264
Trichomonas vaginalis cGMP-inhibited 3,5-cyclic phosphodiesterase, putative 0.0033 0.0113 0.2962
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.0036 0.0639
Plasmodium vivax DNA repair protein REV1, putative 0.0018 0.0032 0.0472
Echinococcus granulosus geranylgeranyl transferase type I beta subunit 0.0018 0.0035 0.0137
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0032 0.0512
Loa Loa (eye worm) hypothetical protein 0.0027 0.0081 0.047
Entamoeba histolytica phospholipid-transporting ATPase IA, putative 0.0016 0.0022 0.0144
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0024 0.0066 0.0543
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0018 0.0032 0.0124
Giardia lamblia CAMP-specific 3,5-cyclic phosphodiesterase 4B 0.0268 0.1383 1
Brugia malayi nuclear hormone receptor family member odr-7 0.0024 0.0066 0.0544
Leishmania major hypothetical protein, conserved 0.0033 0.0113 0.1931
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0051 0.021 0.1413
Trypanosoma brucei hypothetical protein, conserved 0.0033 0.0113 0.1931
Echinococcus multilocularis protein farnesyltransferase alpha subunit 0.0025 0.0072 0.0165
Schistosoma mansoni cgmp-dependent 35-cyclic phosphodiesterase 0.0033 0.0113 0.0466
Trypanosoma brucei hypothetical protein, conserved 0.0018 0.0032 0.0312
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0033 0.0113 0.2962
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0032 0.0512
Treponema pallidum UDP-N-acetylglucosamine 1-carboxyvinyltransferase 0.1867 1 1
Trichomonas vaginalis cation-transporting ATPase, putative 0.004 0.0154 0.4218
Leishmania major DNA polymerase eta, putative 0.0107 0.0514 1
Schistosoma mansoni ATPase 0.0069 0.031 0.1285
Brugia malayi Prenyltransferase and squalene oxidase repeat family protein 0.0018 0.0035 0.0292
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0032 0.0512
Onchocerca volvulus Bile acid receptor homolog 0.0051 0.021 0.1748
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0033 0.0113 0.2962
Trypanosoma brucei DNA damage repair protein, putative 0.0018 0.0032 0.0312
Echinococcus multilocularis serine protein kinase ATM 0.0024 0.0068 0.0156
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0024 0.0066 0.0151
Mycobacterium ulcerans metal cation transporter p-type ATPase a 0.0184 0.0927 0.0912
Trypanosoma cruzi hypothetical protein, conserved 0.0018 0.0035 0.0368
Brugia malayi Membrane calcium atpase protein 3 0.007 0.0315 0.261
Brugia malayi Nuclear hormone receptor-like 1 0.0027 0.0081 0.0672
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0016 0.0025 0.0157
Entamoeba histolytica phospholipid-transporting P-type ATPase, putative 0.0016 0.0022 0.0144
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0089 0.0417 0.1726
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0018 0.0087
Brugia malayi potential phospholipid-transporting ATPase IIB, putative 0.0015 0.0017 0.014
Brugia malayi hypothetical protein 0.0035 0.0126 0.1046
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0016 0.0025 0.0157
Trichomonas vaginalis phospholipid-transporting ATPase, putative 0.0016 0.0022 0.0196
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0033 0.0113 0.2962
Echinococcus granulosus sodium:potassium dependent atpase beta subunit 0.0234 0.1198 0.4963
Plasmodium falciparum phosphodiesterase gamma, putative 0.0033 0.0113 0.2924
Echinococcus multilocularis prostaglandin H2 D isomerase 0.0025 0.0074 0.0171
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0016 0.0025 0.0157
Plasmodium vivax conserved Plasmodium protein, unknown function 0.0049 0.0201 0.5605
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0032 0.0512
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0022 0.0057 0.0802
Echinococcus granulosus Na:K ATPase alpha subunit 0.0185 0.0932 0.3861
Trichomonas vaginalis type I geranylgeranyltransferase beta subunit, putative 0.0067 0.0299 0.8605
Trypanosoma brucei trypanothione reductase 0.0047 0.019 0.3486
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0033 0.0113 0.2962
Loa Loa (eye worm) prenyltransferase and squalene oxidase repeat family protein 0.0018 0.0035 0.0134
Echinococcus multilocularis phospholipid transporting ATPase IA 0.0016 0.0022 0.0046
Brugia malayi nuclear hormone receptor 0.0024 0.0066 0.0544
Entamoeba histolytica calcium-transporting P-type ATPase, putative 0.0076 0.0345 1
Plasmodium falciparum geranylgeranyltransferase, putative 0.0018 0.0035 0.0558
Schistosoma mansoni DNA helicase recq1 0.0022 0.0057 0.0233
Loa Loa (eye worm) hypothetical protein 0.0143 0.071 0.5071
Trichomonas vaginalis DNA helicase recq, putative 0.0022 0.0057 0.126
Trypanosoma cruzi cyclic nucleotide phosphodiesterase 0.0033 0.0113 0.1931
Echinococcus granulosus dual 3'5' cyclic AMP and GMP phosphodiesterase 0.0033 0.0113 0.046
Brugia malayi nuclear receptor NHR-67 0.0024 0.0066 0.0544
Mycobacterium tuberculosis Probable UDP-N-acetylglucosamine 1-carboxyvinyltransferase MurA 0.1341 0.7163 1
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0051 0.021 0.0868
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0032 0.0512
Loa Loa (eye worm) hypothetical protein 0.0037 0.0139 0.0893
Schistosoma mansoni nuclear hormone receptor 0.0051 0.021 0.0868
Loa Loa (eye worm) hypothetical protein 0.0027 0.0081 0.047
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0016 0.0025 0.0157
Brugia malayi E1-E2 ATPase family protein 0.0015 0.0017 0.014
Loa Loa (eye worm) hypothetical protein 0.0024 0.0066 0.0357
Echinococcus multilocularis glutathione S transferase 0.002 0.0043 0.0097
Onchocerca volvulus 0.0032 0.0111 0.0918
Brugia malayi nuclear receptor NHR-88 0.0024 0.0066 0.0544
Leishmania major DNA polymerase kappa, putative 0.0057 0.0245 0.4578
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0016 0.0025 0.0205
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0089 0.0417 0.1721
Loa Loa (eye worm) prenyltransferase alpha subunit repeat containing protein 0.0025 0.0072 0.0401
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.0033 0.0113 0.2962
Plasmodium vivax phosphodiesterase gamma, putative 0.0033 0.0113 0.2924
Brugia malayi steroid hormone receptor 0.0051 0.021 0.1739
Trichomonas vaginalis geranylgeranyl transferase type I beta subunit, putative 0.0067 0.0299 0.8605
Mycobacterium leprae PROBABLE CATION-TRANSPORTER ATPASE I CTPI 0.0158 0.079 0.1082
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0033 0.0113 0.04
Echinococcus granulosus nervana 2 0.0234 0.1198 0.4963
Giardia lamblia Potassium-transporting ATPase alpha chain 1 0.0185 0.0932 0.6697
Trichomonas vaginalis protein farnesyltransferase alpha subunit/RAB geranylgeranyl transferase alpha subunit, putative 0.0025 0.0072 0.1709
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.0036 0.0639
Plasmodium falciparum protein farnesyltransferase subunit beta 0.0067 0.0299 0.8598
Giardia lamblia NADH oxidase lateral transfer candidate 0.0016 0.0025 0.0057
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0051 0.021 0.1739
Trypanosoma brucei P-type H+-ATPase, putative 0.004 0.0154 0.2766
Echinococcus granulosus serine protein kinase ATM 0.0024 0.0068 0.0272
Loa Loa (eye worm) hypothetical protein 0.0051 0.021 0.1413
Entamoeba histolytica myb-like DNA-binding domain containing protein 0.0027 0.0085 0.2071
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.0076 0.0345 1
Onchocerca volvulus Protein ultraspiracle homolog 0.0051 0.021 0.1748
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0033 0.0113 0.2962
Trypanosoma brucei DNA polymerase IV, putative 0.0057 0.0245 0.4578
Trypanosoma brucei DNA polymerase kappa, putative 0.0057 0.0245 0.4578
Loa Loa (eye worm) DR-78 0.0024 0.0066 0.0357
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0032 0.0512
Plasmodium vivax phospholipid-transporting ATPase, putative 0.0016 0.0022 0.0144
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0024 0.0066 0.0151
Toxoplasma gondii plasma membrane-type Ca(2+)-ATPase A1 PMCAA1 0.007 0.0315 0.1129
Entamoeba histolytica phospholipid-transporting P-type ATPase, putative 0.0016 0.0022 0.0144
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0051 0.021 0.0862
Entamoeba histolytica Rab geranylgeranyltransferase alpha subunit, putative 0.0025 0.0072 0.1665
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0057 0.0245 0.0577
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0016 0.0025 0.0157
Schistosoma mansoni plasma membrane calcium-transporting atpase 0.007 0.0315 0.1305
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0016 0.0025 0.0008
Mycobacterium tuberculosis Conserved hypothetical protein 0.0057 0.0245 0.0319
Entamoeba histolytica myb-like DNA-binding domain containing protein 0.0027 0.0085 0.2071
Trichomonas vaginalis chromobox protein, putative 0.0068 0.0304 0.8733
Trypanosoma brucei chrX additional, unordered contigs 0.0018 0.0032 0.0312
Mycobacterium ulcerans UDP-N-acetylglucosamine 1-carboxyvinyltransferase 0.1867 1 1
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0051 0.021 0.0868
Loa Loa (eye worm) calcium ATPase 0.0041 0.0158 0.1034
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0033 0.0113 0.2962
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0022 0.0057 0.0197
Trypanosoma brucei phospholipid-translocating P-type ATPase (flippase), putative 0.0016 0.0022 0.0095
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0022 0.0057 0.0227
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0018 0.0032 0.0109
Schistosoma mansoni cpg binding protein 0.0036 0.0131 0.0539
Trichomonas vaginalis ATPase, class I, type 8B, putative 0.0015 0.0017 0.0053
Echinococcus multilocularis phospholipid transporting ATPase IF 0.0016 0.0022 0.0046
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0018 0.0032 0.0462
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.0036 0.0639
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0025 0.0157
Echinococcus granulosus phospholipid transporting ATPase IIB 0.0015 0.0017 0.0061
Trichomonas vaginalis r2r3-MYB transcription factor, putative 0.0027 0.0085 0.2113
Plasmodium falciparum calcium-transporting ATPase 0.007 0.0315 0.9078
Trypanosoma brucei geranylgeranyl transferase type II beta subunit, putative 0.0018 0.0035 0.0368
Trichomonas vaginalis geranylgeranyl transferase type II beta subunit, putative 0.0067 0.0299 0.8605
Echinococcus granulosus cation transporting atpase worm 0.0015 0.0017 0.0061
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0033 0.0113 0.04
Trypanosoma brucei Protein prenyltransferase alpha subunit repeat, putative 0.0025 0.0072 0.11
Loa Loa (eye worm) hypothetical protein 0.0026 0.0074 0.0421
Echinococcus multilocularis cation transporting atpase worm 0.0015 0.0017 0.0035
Schistosoma mansoni type V p-type atpase isoform 0.0016 0.0022 0.0087
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0027 0.0081 0.0334
Echinococcus granulosus sodium:potassium dependent atpase beta subunit 0.0194 0.098 0.4059
Leishmania major phosphatidylinositol 3-kinase, putative 0.0018 0.0032 0.0305
Schistosoma mansoni DNA polymerase eta 0.0107 0.0514 0.2131
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0032 0.0512
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0016 0.0025 0.0157
Echinococcus multilocularis high affinity cAMP specific 3',5' cyclic 0.0033 0.0113 0.0264
Trypanosoma brucei DNA polymerase kappa, putative 0.0057 0.0245 0.4578
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0035 0.0126 0.0295
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0033 0.0113 0.04
Schistosoma mansoni methyl-cpg binding protein mbd 0.0017 0.0027 0.0108
Brugia malayi MH2 domain containing protein 0.0119 0.0577 0.4776
Giardia lamblia GTOR 0.0018 0.0032 0.0111
Plasmodium vivax geranylgeranyl transferase type2 beta subunit, putative 0.0018 0.0035 0.0558
Brugia malayi orphan nuclear receptor NR2E1 0.0024 0.0066 0.0544
Trypanosoma cruzi hypothetical protein, conserved 0.0025 0.0072 0.11
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.006 0.0261 0.1074
Trypanosoma cruzi geranylgeranyl transferase type II beta subunit, putative 0.0018 0.0035 0.0368
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0032 0.0512
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0032 0.0512
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0016 0.0025 0.0081
Brugia malayi Na,K-ATPase alpha subunit 0.019 0.0962 0.7971
Trypanosoma brucei protein farnesyltransferase beta subunit 0.0067 0.0299 0.5679
Loa Loa (eye worm) hypothetical protein 0.0026 0.0074 0.0421
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0051 0.021 0.0494
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0107 0.0515 0.0697
Trichomonas vaginalis chromobox protein, putative 0.0041 0.0158 0.4326
Entamoeba histolytica phospholipid-transporting P-type ATPase, putative 0.0016 0.0022 0.0144
Giardia lamblia DINP protein human, muc B family 0.0057 0.0245 0.1666
Plasmodium falciparum glutathione S-transferase 0.0025 0.0074 0.1745
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0016 0.0025 0.0237
Trichomonas vaginalis phospholipid-transporting ATPase, putative 0.0016 0.0022 0.0196
Loa Loa (eye worm) hypothetical protein 0.0018 0.0035 0.0134
Schistosoma mansoni ATPase 0.0069 0.031 0.1285
Loa Loa (eye worm) cyclic AMP specific phosphodiesterase PDE4D5A 0.0236 0.1207 0.8712
Leishmania major vacuolar-type Ca2 -ATPase, putative 0.0069 0.031 0.5902
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0033 0.0113 0.2962
Trypanosoma cruzi DNA polymerase kappa, putative 0.0057 0.0245 0.4578
Loa Loa (eye worm) thioredoxin reductase 0.0047 0.019 0.1269
Schistosoma mansoni nuclear receptor nhr-48 0.0024 0.0066 0.027
Toxoplasma gondii prenyltransferase and squalene oxidase repeat-containing protein 0.0067 0.0299 0.1072
Trypanosoma cruzi hypothetical protein, conserved 0.0033 0.0113 0.1931
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0012 0.0001 0.0011
Trypanosoma cruzi calcium motive p-type ATPase, putative 0.007 0.0315 0.5997
Giardia lamblia DNA damage repair protein 0.0018 0.0032 0.0113
Trypanosoma brucei DNA polymerase kappa, putative 0.0057 0.0245 0.4578
Schistosoma mansoni cation-transporting atpase worm 0.0015 0.0017 0.0067
Brugia malayi glutathione transferase 0.0186 0.0941 0.7791
Plasmodium vivax 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0033 0.0113 0.2924
Echinococcus multilocularis protein farnesyltransferase subunit beta 0.0067 0.0299 0.0707
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0027 0.0081 0.0334
Trichomonas vaginalis ATPase, class VI, type 11C, putative 0.0016 0.0022 0.0196
Schistosoma mansoni geranylgeranyl transferase type I beta subunit 0.0018 0.0035 0.0143
Echinococcus granulosus Ca2 transporting ATPase plasma membrane 0.007 0.0315 0.1299
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0033 0.0113 0.2962
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0051 0.021 0.0862
Mycobacterium tuberculosis Probable dehydrogenase 0.0107 0.0515 0.0697
Trypanosoma brucei protein farnesyltransferase alpha subunit, putative 0.0025 0.0072 0.11
Schistosoma mansoni zinc finger protein 0.0021 0.005 0.0204
Echinococcus multilocularis FTZ F1 alpha 0.0051 0.021 0.0494
Brugia malayi ImpB/MucB/SamB family protein 0.0107 0.0514 0.4259
Brugia malayi Probable calcium-transporting ATPase KIAA0703 0.0045 0.0178 0.1471
Loa Loa (eye worm) hypothetical protein 0.0051 0.021 0.1413
Echinococcus multilocularis glutathione S transferase 0.002 0.0043 0.0097
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0119 0.0579 0.0787
Toxoplasma gondii haloacid dehalogenase family hydrolase domain-containing protein 0.0015 0.0017 0.0053
Loa Loa (eye worm) RecQ helicase 0.0022 0.0057 0.0292
Loa Loa (eye worm) E1-E2 ATPase 0.004 0.0154 0.1007
Schistosoma mansoni calcium/calmodulin-dependent 35-cyclic nucleotide phosphodiesterase 0.0033 0.0113 0.0466
Treponema pallidum NADH oxidase 0.0016 0.0025 0.0008
Schistosoma mansoni transcription factor LCR-F1 0.0035 0.0126 0.0521
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0025 0.0157
Loa Loa (eye worm) PHD-finger family protein 0.002 0.0045 0.0209
Trypanosoma brucei ISWI complex protein 0.0015 0.0017 0.001
Schistosoma mansoni nuclear hormone receptor 0.0024 0.0066 0.027
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.007 0.0315 0.9083
Leishmania major phospholipid-translocating P-type ATPase (flippase), putative 0.0016 0.0022 0.0095
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0033 0.0113 0.2962
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0024 0.0066 0.0264
Echinococcus multilocularis copper transporting ATPase 1 0.0015 0.0017 0.0035
Trypanosoma cruzi target of rapamycin kinase 3 0.0018 0.0032 0.0305
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0024 0.0066 0.0543
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0057 0.0245 0.6947
Trichomonas vaginalis geranylgeranyl transferase type beta subunit, putative 0.0067 0.0299 0.8605
Trypanosoma cruzi calcium-transporting ATPase, putative 0.0045 0.0178 0.3231
Echinococcus multilocularis chromobox protein 1 0.0068 0.0304 0.0717
Plasmodium falciparum cGMP-specific phosphodiesterase 0.0033 0.0113 0.2924
Entamoeba histolytica Plasma membrane calcium-transporting ATPase, putative 0.0069 0.031 0.8934
Echinococcus multilocularis Tetracycline resistance leader peptide, TetL 0.0076 0.0345 0.0817
Echinococcus multilocularis cAMP and cAMP inhibited cGMP 3',5' cyclic 0.0033 0.0113 0.0264
Brugia malayi Steroid receptor seven-up type 2 0.0051 0.021 0.1739
Echinococcus granulosus calcium transporting ATPase type 2C member 0.0076 0.0345 0.1425
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0033 0.0113 0.2962
Loa Loa (eye worm) hypothetical protein 0.0024 0.0066 0.0357
Loa Loa (eye worm) calcium/calmodulin-stimulated cyclic nucleotide phosphodiesterase 0.0033 0.0113 0.0703
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0792 0.4205 1
Schistosoma mansoni GST class-mu 0.0025 0.0074 0.0305
Brugia malayi CHD4 protein 0.0015 0.0017 0.014
Brugia malayi calcium ATPase 0.0035 0.0128 0.1059
Schistosoma mansoni sodium/potassium-dependent atpase beta subunit 0.0234 0.1198 0.4966
Leishmania major P-type H -ATPase, putative 0.004 0.0154 0.2766
Leishmania major protein farnesyltransferase alpha subunit, putative 0.0025 0.0072 0.11
Toxoplasma gondii E1-E2 ATPase subfamily protein 0.0035 0.0124 0.044
Schistosoma mansoni hypothetical protein 0.0459 0.2411 1
Trypanosoma cruzi hypothetical protein, conserved 0.0018 0.0035 0.0368
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0033 0.0113 0.2962
Echinococcus multilocularis glutathione S transferase 0.0025 0.0074 0.0171
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0033 0.0113 0.2962
Plasmodium vivax farnesyltransferase beta subunit, putative 0.0067 0.0299 0.8598
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0035 0.0126 0.0514
Loa Loa (eye worm) bromodomain containing protein 0.0017 0.003 0.0095
Echinococcus granulosus plasma membrane calcium transporting ATPase 2 0.0076 0.0345 0.1425
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.0069 0.031 0.894
Trypanosoma brucei phosphatidylinositol kinase related protein, putative 0.0024 0.0068 0.102
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0024 0.0066 0.0264
Trypanosoma brucei DNA polymerase kappa, putative 0.0057 0.0245 0.4578
Plasmodium falciparum DNA repair protein REV1, putative 0.0018 0.0032 0.0472
Echinococcus granulosus high affinity cgmp specific 3' 5' cyclic 0.0033 0.0113 0.046
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0024 0.0066 0.0544
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0027 0.0081 0.047
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0022 0.0057 0.013
Echinococcus multilocularis nervana 2 0.0194 0.098 0.2326
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0032 0.0512
Trypanosoma cruzi Protein prenyltransferase alpha subunit repeat, putative 0.0025 0.0072 0.11
Echinococcus granulosus glutathione S transferase 0.002 0.0043 0.0169
Loa Loa (eye worm) hypothetical protein 0.0027 0.0081 0.047
Brugia malayi nuclear receptor RXR 0.0024 0.0066 0.0544
Loa Loa (eye worm) phosphatidylinositol 3 0.0018 0.0032 0.0111
Loa Loa (eye worm) phosphatidylinositol 3 0.0018 0.0032 0.0111
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0027 0.0081 0.0328
Schistosoma mansoni hypothetical protein 0.002 0.0045 0.0186
Plasmodium vivax calcium-transporting ATPase, putative 0.0076 0.0345 1
Trichomonas vaginalis phospholipid-transporting ATPase, putative 0.0016 0.0022 0.0196
Trypanosoma brucei phospholipid-transporting ATPase 1-like protein, putative 0.0016 0.0022 0.0095
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0033 0.0113 0.04
Echinococcus multilocularis protein prenyltransferase alpha subunit 0.0025 0.0072 0.0165
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0033 0.0113 0.1931
Trichomonas vaginalis pc-MYB2, putative 0.0027 0.0085 0.2113
Schistosoma mansoni protein farnesyltransferase alpha subunit 0.0025 0.0072 0.0294
Loa Loa (eye worm) steroid hormone receptor 0.0051 0.021 0.1413
Trichomonas vaginalis r2r3-MYB transcription factor, putative 0.0028 0.0086 0.2135
Brugia malayi nuclear receptor RXR 0.0027 0.0081 0.0672
Toxoplasma gondii Myb family DNA-binding domain-containing protein 0.0028 0.0086 0.0301
Giardia lamblia Rab geranylgeranyltransferase 0.0025 0.0072 0.04
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0113 0.2962
Schistosoma mansoni calcium-transporting atpase sarcoplasmic/endoplasmic reticulum type (calcium pump) 0.007 0.0315 0.1305
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0142 0.3854
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0024 0.0066 0.0151
Echinococcus granulosus high affinity cAMP specific 3'5' cyclic 0.0033 0.0113 0.046
Loa Loa (eye worm) hypothetical protein 0.0024 0.0066 0.0357
Trichomonas vaginalis cation-transporting ATPase, putative 0.0016 0.0022 0.0196
Trichomonas vaginalis r2r3-MYB transcription factor, putative 0.0027 0.0085 0.2113
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0051 0.021 0.1413
Leishmania major calcium-transporting ATPase, putative 0.007 0.0315 0.5997
Schistosoma mansoni calcium-transporting atpase 2 (atpase 2) 0.007 0.0315 0.1305
Echinococcus granulosus protein farnesyltransferase subunit beta 0.0067 0.0299 0.1234
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0032 0.0512
Echinococcus granulosus nervana 2 0.0234 0.1198 0.4963
Toxoplasma gondii FATC domain-containing protein 0.0024 0.0068 0.0236
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0018 0.0032 0.0305
Brugia malayi Protein prenyltransferase alpha subunit repeat containing protein 0.0025 0.0072 0.0593
Schistosoma mansoni Glutathione S-transferase 28 kDa (GST 28) (GST class-mu) 0.0025 0.0074 0.0305
Trichomonas vaginalis C-MYB, putative 0.0027 0.0085 0.2113
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0018 0.0032 0.0305
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0107 0.0515 0.0697
Brugia malayi ecdysone receptor 0.0024 0.0066 0.0544
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0051 0.021 0.0868
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.0033 0.0113 0.2962
Loa Loa (eye worm) hypothetical protein 0.0033 0.0113 0.0703
Plasmodium falciparum protein farnesyltransferase subunit alpha 0.0025 0.0072 0.1665
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0032 0.0512
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.0033 0.0113 0.0466
Leishmania major aminophospholipid translocase, putative 0.0016 0.0022 0.0095
Trypanosoma brucei DNA polymerase IV, putative 0.0057 0.0245 0.4578
Loa Loa (eye worm) hypothetical protein 0.0024 0.0066 0.0357
Schistosoma mansoni glutathione-S-transferase 0.0025 0.0074 0.0305
Trichomonas vaginalis geranylgeranyl transferase type II beta subunit, putative 0.0067 0.0299 0.8605
Echinococcus multilocularis geranylgeranyl transferase type I beta subunit 0.0018 0.0035 0.0079
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0051 0.021 0.1739
Loa Loa (eye worm) hypothetical protein 0.0051 0.021 0.1413
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0089 0.0417 0.1721
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0033 0.0113 0.2962
Echinococcus multilocularis phospholipid transporting atpase ih phospholipid transporting atpase if 0.0016 0.0022 0.0046
Brugia malayi ecdysteroid receptor 0.0051 0.021 0.1739
Plasmodium falciparum cGMP-specific phosphodiesterase 0.0033 0.0113 0.2924
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0051 0.021 0.0494
Echinococcus granulosus protein farnesyltransferase alpha subunit 0.0025 0.0072 0.0288
Toxoplasma gondii shikimate dehydrogenase substrate binding domain-containing protein 0.0526 0.2774 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0032 0.0512
Entamoeba histolytica hypothetical protein 0.0035 0.0126 0.3328
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0018 0.0032 0.013
Trypanosoma brucei calcium-transporting ATPase, putative 0.0016 0.0022 0.0095
Leishmania major farnesyltransferase beta subunit 0.0067 0.0299 0.5679
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0033 0.0113 0.1931
Echinococcus granulosus methyl CpG binding domain protein 2 0.0017 0.0027 0.0102
Trypanosoma cruzi Calcium ATPase SERCA-like 0.0069 0.031 0.5902
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0025 0.0157
Echinococcus granulosus nervana 2 0.0194 0.098 0.4059
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0016 0.0025 0.0054
Loa Loa (eye worm) calcium-transporting ATPase sarcoplasmic/endoplasmic reticulum type 0.0045 0.0178 0.1176
Entamoeba histolytica protein farnesyltransferase alpha subunit, putative 0.0025 0.0072 0.1665
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0035 0.0126 0.0515
Schistosoma mansoni transmemberane protein 0.0234 0.1198 0.4966
Brugia malayi calcium ATPase 0.0035 0.0124 0.1028
Echinococcus multilocularis sodium:potassium dependent atpase beta subunit 0.0234 0.1198 0.2845
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0018 0.0032 0.0305
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0032 0.0512
Echinococcus multilocularis Na+:K+ ATPase alpha subunit 0.0185 0.0932 0.2213
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0033 0.0113 0.2962
Brugia malayi Nuclear hormone receptor-like 1 0.0027 0.0081 0.0672
Trypanosoma brucei DNA polymerase kappa, putative 0.0057 0.0245 0.4578
Brugia malayi Sodium/potassium-transporting ATPase alpha-3 chain, putative 0.0035 0.0124 0.1028
Schistosoma mansoni zinc finger protein 0.0015 0.0017 0.0069
Echinococcus multilocularis dna polymerase kappa 0.0057 0.0245 0.0577
Trichomonas vaginalis r2r3-MYB transcription factor, putative 0.0027 0.0085 0.2113
Loa Loa (eye worm) phospholipid-transporting ATPase ID 0.0016 0.0022 0.0035
Trichomonas vaginalis protein farnesyltransferase alpha subunit, putative 0.0025 0.0072 0.1709
Loa Loa (eye worm) nuclear receptor NHR-67 0.0024 0.0066 0.0357
Mycobacterium tuberculosis Probable oxidoreductase 0.0119 0.0579 0.0787
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0089 0.0417 0.0986

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) = 1 uM Inhibition of farnesyl transferase (FTase) of rat brain ChEMBL. No reference
IC50 (binding) = 1 uM Inhibition of farnesyl transferase (FTase) of rat brain ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

No external resources registered for this compound

Bibliographic References

No literature references available for this target.

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