Detailed information for compound 75490

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 674.55 | Formula: C29H31IN4O5S
  • H donors: 2 H acceptors: 4 LogP: 3.78 Rotable bonds: 11
    Rule of 5 violations (Lipinski): 2
  • SMILES: O=C(NC1C(=O)N2C1SC(C2C(=O)OCCNC(=O)c1c[n+](C)cc2c1cccc2)(C)C)Cc1ccccc1.[I-]
  • InChi: 1S/C29H30N4O5S.HI/c1-29(2)24(33-26(36)23(27(33)39-29)31-22(34)15-18-9-5-4-6-10-18)28(37)38-14-13-30-25(35)21-17-32(3)16-19-11-7-8-12-20(19)21;/h4-12,16-17,23-24,27H,13-15H2,1-3H3,(H-,30,31,34,35);1H
  • InChiKey: QANUFZFXVFEYDK-UHFFFAOYSA-N  

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity

Obtained from network model

Ranking Plot


Putative Targets List


Species Potential target Raw Global Species
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0072 0.0278 0.2217
Brugia malayi Calcitonin receptor-like protein seb-1 0.0054 0.0194 0.0822
Brugia malayi Cytochrome P450 family protein 0.0013 0.0006 0.0023
Echinococcus granulosus thyrotropin releasing hormone receptor 0.004 0.0129 0.0316
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0358 0.161 0.2235
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.0072 0.0278 0.2217
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0018 0.0028 0.0224
Leishmania major cAMP phosphodiesterase A, putative;with=GeneDB:LinJ18_V3.1100 0.0072 0.0278 0.4072
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0072 0.0278 0.2217
Entamoeba histolytica myb-like DNA-binding domain containing protein 0.0059 0.022 0.488
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0034 0.0101 0.0226
Mycobacterium ulcerans NADPH dependent 2,4-dienoyl-CoA reductase FadH 0.0014 0.001 0.0005
Onchocerca volvulus 0.004 0.0129 0.1124
Echinococcus granulosus dna polymerase eta 0.0129 0.0545 0.133
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0069 0.0267 0.3907
Trypanosoma brucei 3', 5'-cyclic nucleotide phosphodiesterase, putative 0.0072 0.0278 0.4072
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0017 0.0023 0.0265
Echinococcus multilocularis lamin dm0 0.0029 0.008 0.0175
Mycobacterium ulcerans dehydrogenase 0.0014 0.001 0.0005
Schistosoma mansoni rhodopsin-like orphan GPCR 0.004 0.0129 0.0316
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0398 0.1796 0.2495
Trichomonas vaginalis glucosylceramidase, putative 0.0185 0.0802 0.6405
Trichomonas vaginalis r2r3-MYB transcription factor, putative 0.0059 0.022 0.1753
Brugia malayi MH1 domain containing protein 0.0035 0.0106 0.0448
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0291 0.1295 0.4814
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.0072 0.0278 0.2217
Brugia malayi Uncoordinated protein 44 0.0014 0.0008 0.0035
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0028 0.0224
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0028 0.0224
Echinococcus multilocularis mothers against decapentaplegic 2 0.0016 0.0016 0.0019
Echinococcus multilocularis apoptosis inducing factor 1 mitochondrial 0.0014 0.001 0.0005
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0014 0.001 0.0072
Schistosoma mansoni lamin 0.0029 0.008 0.0195
Echinococcus granulosus g-protein coupled receptor 0.004 0.0129 0.0316
Brugia malayi G protein-coupled receptor 0.004 0.0129 0.0549
Mycobacterium leprae probable 3-phosphoshikimate 1-carboxyvinyl transferase AroA (5-ENOLPYRUVYLSHIKIMATE-3-PHOSPHATE SYNTHASE) (EPSP SYNTHASE) (EPSPS 0.0609 0.2778 0.3869
Trichomonas vaginalis DNA helicase recq, putative 0.0043 0.0142 0.1133
Trypanosoma cruzi target of rapamycin kinase 3 0.0039 0.0125 0.1781
Onchocerca volvulus 0.0014 0.001 0.009
Echinococcus granulosus survival motor neuron protein 1 0.0258 0.1142 0.2787
Treponema pallidum ATP-dependent DNA helicase 0.0015 0.0012 0.0001
Schistosoma mansoni amine GPCR 0.004 0.0129 0.0316
Schistosoma mansoni rhodopsin-like orphan GPCR 0.004 0.0129 0.0316
Schistosoma mansoni biogenic amine (dopamine) receptor 0.004 0.0129 0.0316
Loa Loa (eye worm) hypothetical protein 0.004 0.0129 0.0481
Plasmodium vivax SET domain protein, putative 0.0034 0.0101 0.1374
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0029 0.0078 0.019
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.059 0.2691 0.6569
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.004 0.0129 0.0316
Echinococcus multilocularis jun protein 0.0082 0.0323 0.077
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0034 0.0101 0.0226
Loa Loa (eye worm) hypothetical protein 0.004 0.0129 0.0481
Brugia malayi Serotonin receptor 0.004 0.0129 0.0549
Echinococcus granulosus tm gpcr rhodopsin 0.004 0.0129 0.0316
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0054 0.0194 0.0822
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0072 0.0278 0.0966
Trypanosoma brucei DNA polymerase kappa, putative 0.0107 0.0442 0.6528
Trichomonas vaginalis PIKK family atypical protein kinase 0.0016 0.002 0.0156
Schistosoma mansoni DNA polymerase IV / kappa 0.0031 0.0088 0.0214
Loa Loa (eye worm) MH2 domain-containing protein 0.0512 0.2327 0.8648
Leishmania major cAMP-specific phosphodiesterase, putative 0.0072 0.0278 0.4072
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.0014 0.0008 0.000000066063
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.004 0.0129 0.0296
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.004 0.0129 0.0316
Schistosoma mansoni DNA helicase recq1 0.0029 0.0078 0.019
Echinococcus multilocularis isocitrate dehydrogenase 0.0017 0.0023 0.0037
Entamoeba histolytica hypothetical protein 0.0109 0.045 1
Brugia malayi hypothetical protein 0.0133 0.056 0.2377
Trichomonas vaginalis PIKK family atypical protein kinase 0.0042 0.0138 0.1099
Loa Loa (eye worm) hypothetical protein 0.0017 0.0022 0.0083
Echinococcus granulosus tar DNA binding protein 0.0137 0.0583 0.1422
Toxoplasma gondii isocitrate dehydrogenase 0.0017 0.0023 0.0047
Schistosoma mansoni rhodopsin-like orphan GPCR 0.004 0.0129 0.0316
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0109 0.045 0.1098
Plasmodium vivax type II NADH:ubiquinone oxidoreductase, putative 0.0014 0.001 0.0018
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0072 0.0278 0.0966
Schistosoma mansoni lipoxygenase 0.006 0.0223 0.0544
Onchocerca volvulus 0.0039 0.0126 0.1092
Entamoeba histolytica hypothetical protein 0.0109 0.045 1
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0072 0.0278 0.2217
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.002 0.0039 0.0143
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.004 0.0129 0.0548
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0014 0.001 0.0072
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0028 0.0224
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0129 0.0543 0.4337
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0072 0.0278 0.2217
Brugia malayi RNA binding protein 0.0137 0.0583 0.2472
Brugia malayi hypothetical protein 0.0064 0.0241 0.1024
Loa Loa (eye worm) hypothetical protein 0.004 0.0129 0.0481
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0072 0.0278 0.2217
Leishmania major cathepsin L-like protease 0.0069 0.0267 0.3907
Loa Loa (eye worm) hypothetical protein 0.0129 0.0545 0.2024
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.002 0.0038 0.0483
Loa Loa (eye worm) programmed cell death 8 0.0014 0.001 0.0039
Loa Loa (eye worm) hypothetical protein 0.004 0.0129 0.0481
Schistosoma mansoni cpg binding protein 0.0059 0.0219 0.0534
Mycobacterium ulcerans NADH dehydrogenase 0.0014 0.001 0.0005
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0023 0.0051 0.0679
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0054 0.0196 0.2856
Schistosoma mansoni chromobox protein 0.0068 0.026 0.0634
Echinococcus multilocularis survival motor neuron protein 1 0.0258 0.1142 0.2773
Trypanosoma cruzi cAMP-specific phosphodiesterase, putative 0.0072 0.0278 0.4072
Leishmania major cathepsin L-like protease 0.0069 0.0267 0.3907
Trypanosoma brucei DNA polymerase IV, putative 0.0129 0.0543 0.8045
Echinococcus granulosus chromobox protein 1 0.0068 0.026 0.0634
Schistosoma mansoni alpha-1 adrenergic receptor 0.004 0.0129 0.0316
Echinococcus multilocularis dnaJ subfamily B 0.0843 0.3867 0.9438
Giardia lamblia DINP protein human, muc B family 0.0107 0.0442 0.1609
Trichomonas vaginalis r2r3-MYB transcription factor, putative 0.006 0.0221 0.1764
Schistosoma mansoni terminal deoxycytidyl transferase 0.01 0.0408 0.0997
Trichomonas vaginalis set domain proteins, putative 0.0259 0.115 0.9183
Loa Loa (eye worm) CHromoDomain protein family member 0.0015 0.0011 0.004
Loa Loa (eye worm) hypothetical protein 0.0054 0.0194 0.072
Brugia malayi Probable 3',5'-cyclic phosphodiesterase R153.1, putative 0.0519 0.2356 1
Mycobacterium ulcerans hypothetical protein 0.0031 0.0088 0.0082
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0066 0.0529
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0029 0.0078 0.017
Schistosoma mansoni neuropeptide receptor 0.004 0.0129 0.0316
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0107 0.0442 0.0603
Onchocerca volvulus 0.003 0.0082 0.0715
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0025 0.0057 0.0458
Schistosoma mansoni hypothetical protein 0.004 0.0129 0.0316
Schistosoma mansoni opsin-like receptor 0.004 0.0129 0.0316
Trichomonas vaginalis glutamate synthase, putative 0.0014 0.001 0.0083
Leishmania major cathepsin L-like protease 0.0018 0.0028 0.0337
Brugia malayi Probable 3',5'-cyclic phosphodiesterase C32E12.2, putative 0.0072 0.0278 0.1178
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0121 0.0963
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0016 0.0016 0.0061
Leishmania major cathepsin L-like protease 0.0018 0.0028 0.0337
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0054 0.0196 0.2856
Schistosoma mansoni rhodopsin-like orphan GPCR 0.004 0.0129 0.0316
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0039 0.0126 0.012
Brugia malayi sulfakinin receptor protein 0.004 0.0129 0.0549
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0127 0.0533 0.1301
Trypanosoma cruzi hypothetical protein, conserved 0.0039 0.0126 0.1798
Trichomonas vaginalis conserved hypothetical protein 0.0072 0.0278 0.2217
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.0014 0.0008 0.002
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0072 0.0278 0.0966
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0014 0.001 0.0072
Schistosoma mansoni camp/cgmp cyclic nucleotide phosphodiesterase 0.0072 0.0278 0.0678
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0025 0.0057 0.0458
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0014 0.001 0.0025
Plasmodium vivax ataxin-2 like protein, putative 0.0077 0.0299 0.4366
Loa Loa (eye worm) nuclear factor I 0.0019 0.0033 0.0123
Trypanosoma cruzi hypothetical protein, conserved 0.0014 0.001 0.0072
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0049 0.0171 0.38
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0049 0.0171 0.38
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0017 0.0023 0.0265
Echinococcus multilocularis chromobox protein 1 0.0068 0.026 0.0615
Trichomonas vaginalis r2r3-MYB transcription factor, putative 0.0059 0.022 0.1753
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0049 0.0171 0.0726
Brugia malayi polk-prov protein 0.006 0.0222 0.0944
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0113 0.0899
Brugia malayi Melatonin receptor type 1A 0.004 0.0129 0.0549
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.0072 0.0278 0.0678
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0017 0.0023 0.0265
Brugia malayi hypothetical protein 0.004 0.0129 0.0549
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0034 0.0103 0.0251
Loa Loa (eye worm) hypothetical protein 0.0346 0.1551 0.5765
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0072 0.0278 0.4072
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0066 0.0529
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0251 0.1109 0.1536
Echinococcus granulosus lipoxygenase domain containing protein 0.0021 0.0043 0.0105
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0017 0.0022 0.0035
Loa Loa (eye worm) hypothetical protein 0.004 0.0129 0.0481
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0072 0.0278 0.2217
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0054 0.0196 0.2856
Onchocerca volvulus 0.004 0.0129 0.1124
Brugia malayi SET domain containing protein 0.0014 0.0007 0.0028
Brugia malayi hypothetical protein 0.0049 0.0173 0.0735
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0072 0.0278 0.2217
Schistosoma mansoni cellular tumor antigen P53 0.0054 0.0194 0.0473
Echinococcus granulosus neuropeptide receptor A26 0.0541 0.2461 0.6008
Trypanosoma cruzi cruzipain precursor, putative 0.0069 0.0267 0.3907
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0069 0.0267 0.3907
Trypanosoma brucei DNA damage repair protein, putative 0.0031 0.0088 0.1227
Onchocerca volvulus Netrin receptor homolog 0.0014 0.0008 0.0071
Echinococcus granulosus cathepsin l1 0.0018 0.0028 0.0068
Mycobacterium tuberculosis Probable lipase LipE 0.0039 0.0126 0.0161
Loa Loa (eye worm) hypothetical protein 0.0039 0.0126 0.0467
Plasmodium vivax glutathione reductase, putative 0.0157 0.0674 1
Schistosoma mansoni cathepsin F (C01 family) 0.0018 0.0028 0.0068
Schistosoma mansoni cgmp-dependent 35-cyclic phosphodiesterase 0.0072 0.0278 0.0678
Plasmodium vivax ferrodoxin reductase, putative 0.0014 0.001 0.0018
Onchocerca volvulus 0.004 0.0129 0.1124
Loa Loa (eye worm) melatonin receptor type 1A 0.004 0.0129 0.0481
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0049 0.0171 0.2476
Loa Loa (eye worm) hypothetical protein 0.0054 0.0194 0.0721
Echinococcus multilocularis G-protein coupled receptor, putative 0.004 0.0129 0.0296
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0014 0.001 0.0083
Onchocerca volvulus 0.004 0.0129 0.1124
Schistosoma mansoni cathepsin F (C01 family) 0.0018 0.0028 0.0068
Loa Loa (eye worm) hypothetical protein 0.004 0.0129 0.0481
Trypanosoma cruzi trypanothione reductase, putative 0.0054 0.0196 0.2856
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0016 0.002 0.0048
Echinococcus granulosus g protein coupled receptor 0.004 0.0129 0.0316
Echinococcus multilocularis orexin receptor type 2 0.004 0.0129 0.0296
Trypanosoma brucei 2,4-dienoyl-coa reductase-like protein 0.0014 0.001 0.0072
Trypanosoma cruzi PAB1-binding protein , putative 0.0077 0.0299 0.4397
Schistosoma mansoni biogenic amine (5HT) receptor 0.004 0.0129 0.0316
Echinococcus multilocularis cathepsin L cysteine protease 0.0018 0.0028 0.0049
Echinococcus granulosus chromobox protein 1 0.0068 0.026 0.0634
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.004 0.0129 0.0296
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0054 0.0196 0.2856
Brugia malayi CHD4 protein 0.0015 0.0011 0.0045
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0091 0.0727
Brugia malayi G-protein coupled receptor 0.004 0.0129 0.0549
Echinococcus multilocularis rhodopsin orphan GPCR 0.004 0.0129 0.0296
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0018 0.0028 0.0049
Trypanosoma cruzi hypothetical protein, conserved 0.0072 0.0278 0.4072
Schistosoma mansoni amine GPCR 0.004 0.0129 0.0316
Loa Loa (eye worm) hypothetical protein 0.0072 0.0278 0.1032
Toxoplasma gondii ABC1 family protein 0.0039 0.0126 0.0417
Brugia malayi hypothetical protein 0.004 0.0129 0.0549
Schistosoma mansoni smad1 5 8 and 0.0035 0.0106 0.0258
Schistosoma mansoni ap endonuclease 0.002 0.0039 0.0094
Plasmodium vivax phosphodiesterase gamma, putative 0.0072 0.0278 0.404
Onchocerca volvulus 0.004 0.0129 0.1124
Schistosoma mansoni survival motor neuron protein 0.0053 0.0188 0.0458
Loa Loa (eye worm) hypothetical protein 0.0014 0.0009 0.0034
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0072 0.0278 0.2217
Brugia malayi Probable 3',5'-cyclic phosphodiesterase R153.1, putative 0.0072 0.0278 0.1178
Echinococcus multilocularis Polycystic kidney disease protein 0.0021 0.0043 0.0086
Loa Loa (eye worm) hypothetical protein 0.004 0.0129 0.0481
Loa Loa (eye worm) hypothetical protein 0.0039 0.0126 0.0467
Brugia malayi Isocitrate dehydrogenase 0.0017 0.0023 0.0099
Mycobacterium ulcerans hypothetical protein 0.0039 0.0126 0.012
Trichomonas vaginalis helicase, putative 0.0013 0.0006 0.0045
Trichomonas vaginalis dihydrolipoamide dehydrogenase, putative 0.0014 0.001 0.0083
Loa Loa (eye worm) hypothetical protein 0.0077 0.0299 0.1112
Trypanosoma cruzi 2,4-dienoyl-coa reductase-like protein, putative 0.0014 0.001 0.0072
Onchocerca volvulus 0.004 0.0129 0.1124
Loa Loa (eye worm) hypothetical protein 0.0015 0.0012 0.0044
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0017 0.0023 0.0194
Schistosoma mansoni voltage-gated potassium channel 0.0019 0.003 0.0074
Echinococcus multilocularis rhodopsin orphan GPCR 0.004 0.0129 0.0296
Schistosoma mansoni neuropeptide F-like receptor 0.004 0.0129 0.0316
Trichomonas vaginalis PIKK family atypical protein kinase 0.0016 0.002 0.0156
Loa Loa (eye worm) hypothetical protein 0.004 0.0129 0.0481
Plasmodium falciparum cysteine proteinase falcipain 3 0.0018 0.0028 0.0267
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0014 0.001 0.0025
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0015 0.0012 0.0094
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0049 0.0171 0.2476
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.004 0.0129 0.0316
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0072 0.0278 0.2217
Loa Loa (eye worm) doublecortin family protein 0.0021 0.0043 0.016
Echinococcus multilocularis allatostatin A receptor 0.004 0.0129 0.0296
Mycobacterium ulcerans UDP-N-acetylglucosamine 1-carboxyvinyltransferase 0.2161 1 1
Schistosoma mansoni Smad4 0.0016 0.0016 0.0039
Trichomonas vaginalis cGMP-inhibited 3,5-cyclic phosphodiesterase, putative 0.0072 0.0278 0.2217
Mycobacterium tuberculosis Probable oxidoreductase 0.0398 0.1796 0.2495
Schistosoma mansoni tar DNA-binding protein 0.0137 0.0583 0.1422
Brugia malayi G protein-coupled receptor F59B2.13 0.004 0.0129 0.0549
Schistosoma mansoni voltage-gated potassium channel 0.0051 0.018 0.044
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0017 0.0022 0.0095
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.004 0.0129 0.0296
Loa Loa (eye worm) hypothetical protein 0.004 0.0129 0.0481
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0054 0.0196 0.0191
Loa Loa (eye worm) histone methyltransferase 0.002 0.0034 0.0126
Brugia malayi Cathepsin L-like precursor 0.0018 0.0028 0.0119
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.002 0.0039 0.0105
Echinococcus multilocularis rhodopsin orphan GPCR 0.004 0.0129 0.0296
Echinococcus multilocularis biogenic amine (5HT) receptor 0.004 0.0129 0.0296
Trypanosoma cruzi NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0014 0.001 0.0072
Echinococcus multilocularis tar DNA binding protein 0.0137 0.0583 0.1405
Entamoeba histolytica NAD(FAD)-dependent dehydrogenase, putative 0.0014 0.001 0.0231
Echinococcus granulosus neuropeptides capa receptor 0.004 0.0129 0.0316
Mycobacterium ulcerans NADH dehydrogenase Ndh1 0.0014 0.001 0.0005
Echinococcus granulosus thioredoxin glutathione reductase 0.0157 0.0674 0.1645
Schistosoma mansoni sulfide quinone reductase 0.0014 0.001 0.0025
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.004 0.0129 0.0548
Mycobacterium tuberculosis Probable reductase 0.0358 0.161 0.2235
Loa Loa (eye worm) hypothetical protein 0.004 0.0129 0.0481
Trichomonas vaginalis cAMP and cAMP-inhibited cGMP 3,5-cyclic phosphodiesterase, putative 0.0072 0.0278 0.2217
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0038 0.0121 0.1048
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0054 0.0196 0.2856
Brugia malayi beta-lactamase family protein 0.0039 0.0126 0.0533
Schistosoma mansoni voltage-gated potassium channel 0.0013 0.0005 0.0013
Entamoeba histolytica exodeoxyribonuclease III, putative 0.002 0.0039 0.0856
Echinococcus granulosus neuropeptide receptor 0.004 0.0129 0.0316
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0069 0.0267 0.3907
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.004 0.0129 0.0316
Loa Loa (eye worm) RecQ helicase 0.0043 0.0142 0.0527
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.002 0.0039 0.0441
Loa Loa (eye worm) hypothetical protein 0.004 0.0129 0.0481
Schistosoma mansoni hypothetical protein 0.0892 0.4097 1
Trypanosoma cruzi cysteine peptidase, putative 0.0069 0.0267 0.3907
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0072 0.0278 0.0966
Echinococcus multilocularis g protein coupled receptor 0.004 0.0129 0.0296
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0015 0.0012 0.0094
Schistosoma mansoni voltage-gated potassium channel 0.0051 0.018 0.044
Brugia malayi bZIP transcription factor family protein 0.0082 0.0323 0.137
Mycobacterium tuberculosis Conserved hypothetical protein 0.01 0.0408 0.0556
Echinococcus granulosus fmrfamide receptor 0.004 0.0129 0.0316
Entamoeba histolytica thioredoxin reductase, putative 0.0014 0.001 0.0231
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0014 0.001 0.0231
Echinococcus multilocularis NADPH:adrenodoxin oxidoreductase 0.0014 0.001 0.0005
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.004 0.0129 0.0316
Echinococcus granulosus somatostatin receptor 0.004 0.0129 0.0316
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0016 0.002 0.021
Brugia malayi hypothetical protein 0.0258 0.1142 0.4846
Brugia malayi Bloom's syndrome protein homolog 0.0043 0.0142 0.0602
Trichomonas vaginalis DNA helicase recq, putative 0.0032 0.0091 0.0727
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0035 0.0106 0.0258
Leishmania major cysteine peptidase A (CPA) 0.0018 0.0028 0.0337
Onchocerca volvulus 0.0039 0.0126 0.1092
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0072 0.0278 0.0678
Echinococcus multilocularis rhodopsin orphan GPCR 0.004 0.0129 0.0296
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0358 0.161 0.2235
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0028 0.0224
Leishmania major hypothetical protein, conserved 0.0014 0.001 0.0072
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0072 0.0278 0.2217
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.004 0.0129 0.0296
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0072 0.0278 0.2217
Trichomonas vaginalis cAMP and cAMP-inhibited cGMP 3,5-cyclic phosphodiesterase, putative 0.0072 0.0278 0.2217
Onchocerca volvulus 0.004 0.0129 0.1124
Trichomonas vaginalis PIKK family atypical protein kinase 0.0049 0.0171 0.1365
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0107 0.0442 0.6528
Brugia malayi gonadotropin-releasing hormone receptor 2 0.004 0.0129 0.0549
Entamoeba histolytica pyridine nucleotide-disulfide oxidoreductase family protein 0.0014 0.001 0.0231
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0096 0.0766
Trichomonas vaginalis D-aminoacylase, putative 0.0039 0.0126 0.1004
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0016 0.002 0.0083
Schistosoma mansoni neuropeptide receptor 0.004 0.0129 0.0316
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.002 0.0039 0.0028
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0015 0.0013 0.0048
Plasmodium falciparum phosphodiesterase delta, putative 0.0072 0.0278 0.4029
Echinococcus granulosus dna polymerase kappa 0.0129 0.0543 0.1326
Echinococcus multilocularis cysteine protease 0.0018 0.0028 0.0049
Trypanosoma brucei DNA polymerase kappa, putative 0.0076 0.0297 0.4368
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0032 0.0091 0.128
Schistosoma mansoni amine GPCR 0.004 0.0129 0.0316
Echinococcus multilocularis neuropeptide FF receptor 2 0.004 0.0129 0.0296
Loa Loa (eye worm) intermediate filament protein 0.0029 0.008 0.0297
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0054 0.0196 0.0479
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.004 0.0129 0.1124
Mycobacterium leprae conserved hypothetical protein 0.0039 0.0126 0.0161
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0014 0.001 0.0083
Entamoeba histolytica myb-like DNA-binding domain containing protein 0.0059 0.022 0.488
Brugia malayi Cathepsin L-like precursor 0.0018 0.0028 0.0119
Loa Loa (eye worm) CXXC zinc finger family protein 0.0059 0.0219 0.0813
Leishmania major hypothetical protein, conserved 0.0014 0.001 0.0072
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0031 0.0089 0.0217
Echinococcus granulosus biogenic amine 5HT receptor 0.004 0.0129 0.0316
Schistosoma mansoni hypothetical protein 0.0017 0.0022 0.0055
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0113 0.0899
Trichomonas vaginalis glucosylceramidase, putative 0.0185 0.0802 0.6405
Brugia malayi latrophilin 2 splice variant baaae 0.0037 0.0114 0.0486
Trypanosoma cruzi hypothetical protein, conserved 0.0072 0.0278 0.4072
Trichomonas vaginalis ap endonuclease, putative 0.002 0.0039 0.0308
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0015 0.0013 0.0032
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0358 0.161 0.2235
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.004 0.0129 0.0316
Echinococcus granulosus potassium:sodium hyperpolarization activated 0.0015 0.0013 0.0032
Trypanosoma cruzi hypothetical protein, conserved 0.0014 0.001 0.0072
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0113 0.0899
Brugia malayi Cathepsin L-like precursor 0.0018 0.0028 0.0119
Plasmodium vivax cyclic nucleotide phosphodiesterase, putative 0.0072 0.0278 0.404
Brugia malayi putative neuropeptide receptor 0.004 0.0129 0.0549
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0028 0.0224
Trypanosoma cruzi hypothetical protein, conserved 0.0072 0.0278 0.4072
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0072 0.0278 0.0966
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0054 0.0196 0.2856
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0026 0.0063 0.0803
Trichomonas vaginalis PIKK family atypical protein kinase 0.0039 0.0124 0.0993
Loa Loa (eye worm) PDE1B protein 0.0072 0.0278 0.1032
Entamoeba histolytica recQ family DNA helicase 0.0015 0.0012 0.0263
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0028 0.0224
Plasmodium falciparum LCCL domain-containing protein 0.0021 0.0043 0.0494
Echinococcus multilocularis mothers against decapentaplegic 5 0.0035 0.0106 0.0238
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0072 0.0278 0.4072
Echinococcus granulosus biogenic amine 5HT receptor 0.004 0.0129 0.0316
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0078 0.0622
Entamoeba histolytica deoxycytidyl transferase, putative 0.01 0.0408 0.9075
Trichomonas vaginalis PIKK family atypical protein kinase 0.0039 0.0124 0.0993
Loa Loa (eye worm) hypothetical protein 0.0038 0.0121 0.0448
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.002 0.0039 0.0033
Plasmodium vivax 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0072 0.0278 0.404
Plasmodium vivax vivapain-2 0.0018 0.0028 0.0284
Trypanosoma brucei DNA polymerase IV, putative 0.0129 0.0543 0.8045
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0045 0.0152 0.0372
Trypanosoma brucei DNA polymerase kappa, putative 0.0076 0.0297 0.4368
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0028 0.0224
Plasmodium vivax NAD(P)H-dependent glutamate synthase, putative 0.0014 0.001 0.0018
Brugia malayi neuropeptide F receptor 0.004 0.0129 0.0549
Loa Loa (eye worm) hypothetical protein 0.004 0.0129 0.0481
Echinococcus granulosus high affinity cgmp specific 3' 5' cyclic 0.0072 0.0278 0.0678
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0028 0.0224
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0028 0.0227
Loa Loa (eye worm) MH2 domain-containing protein 0.0016 0.0016 0.0059
Echinococcus granulosus rhodopsin orphan GPCR 0.004 0.0129 0.0316
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0014 0.0009 0.0002
Toxoplasma gondii exonuclease III APE 0.002 0.0039 0.0102
Trichomonas vaginalis glucosylceramidase, putative 0.0185 0.0802 0.6405
Echinococcus multilocularis hyperpolarization activated cyclic 0.0015 0.0013 0.0012
Onchocerca volvulus 0.004 0.0129 0.1124
Trichomonas vaginalis r2r3-MYB transcription factor, putative 0.0059 0.022 0.1753
Onchocerca volvulus Neuropeptide F receptor homolog 0.004 0.0129 0.1124
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.002 0.0039 0.0494
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0016 0.0017 0.0042
Echinococcus multilocularis g protein coupled receptor 0.004 0.0129 0.0296
Schistosoma mansoni growth hormone secretagogue receptor 0.004 0.0129 0.0316
Mycobacterium ulcerans hypothetical protein 0.0014 0.001 0.0005
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0015 0.0011 0.0026
Echinococcus granulosus Ankyrin 0.0014 0.0009 0.0021
Schistosoma mansoni blooms syndrome DNA helicase 0.0028 0.0073 0.0179
Loa Loa (eye worm) hypothetical protein 0.004 0.0129 0.0481
Schistosoma mansoni rhodopsin-like orphan GPCR 0.004 0.0129 0.0316
Onchocerca volvulus 0.004 0.0129 0.1124
Echinococcus granulosus neuropeptide FF receptor 2 0.004 0.0129 0.0316
Schistosoma mansoni peptide (allatostatin)-like receptor 0.004 0.0129 0.0316
Trypanosoma brucei hypothetical protein, conserved 0.0031 0.0088 0.1227
Loa Loa (eye worm) hypothetical protein 0.004 0.0129 0.0481
Mycobacterium tuberculosis Probable hydrolase 0.0039 0.0126 0.0161
Trichomonas vaginalis MYB72, putative 0.0059 0.022 0.1753
Schistosoma mansoni hypothetical protein 0.0843 0.3867 0.9439
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0054 0.0196 0.0191
Entamoeba histolytica myb-like DNA-binding domain containing protein 0.0059 0.022 0.488
Brugia malayi hypothetical protein 0.004 0.0129 0.0549
Echinococcus granulosus rhodopsin orphan GPCR 0.004 0.0129 0.0316
Echinococcus multilocularis somatostatin receptor 0.004 0.0129 0.0296
Loa Loa (eye worm) hypothetical protein 0.0079 0.0312 0.1161
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0014 0.001 0.0083
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0028 0.0224
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0137 0.0583 0.2165
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0016 0.002 0.021
Trichomonas vaginalis r2r3-MYB transcription factor, putative 0.006 0.0221 0.1764
Loa Loa (eye worm) latrophilin receptor protein 2 0.0017 0.0022 0.0083
Schistosoma mansoni hypothetical protein 0.004 0.0129 0.0316
Loa Loa (eye worm) hypothetical protein 0.004 0.0129 0.0481
Loa Loa (eye worm) hypothetical protein 0.0029 0.0078 0.0289
Mycobacterium ulcerans NADH dehydrogenase Ndh 0.0014 0.001 0.0005
Schistosoma mansoni hypothetical protein 0.0034 0.0103 0.0251
Plasmodium falciparum 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0072 0.0278 0.4029
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0017 0.0023 0.0037
Trichomonas vaginalis PIKK family atypical protein kinase 0.0013 0.0004 0.0034
Plasmodium falciparum thioredoxin reductase 0.0054 0.0196 0.2803
Schistosoma mansoni opsin-like receptor 0.004 0.0129 0.0316
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0039 0.0126 0.0161
Trypanosoma brucei DNA polymerase kappa, putative 0.0129 0.0543 0.8045
Leishmania major hypothetical protein, conserved 0.0014 0.001 0.0072
Schistosoma mansoni rhodopsin-like orphan GPCR 0.004 0.0129 0.0316
Echinococcus multilocularis dna polymerase eta 0.0129 0.0545 0.1312
Echinococcus granulosus rhodopsin orphan GPCR 0.004 0.0129 0.0316
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0072 0.0278 0.2217
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0069 0.0549
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0072 0.0278 0.2217
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0028 0.0224
Brugia malayi TAR-binding protein 0.0137 0.0583 0.2472
Onchocerca volvulus 0.0053 0.0188 0.1631
Echinococcus granulosus geminin 0.0892 0.4097 1
Echinococcus granulosus tm gpcr rhodopsin 0.004 0.0129 0.0316
Schistosoma mansoni neuropeptide F-like receptor 0.004 0.0129 0.0316
Echinococcus granulosus neuropeptide Y receptor 0.004 0.0129 0.0316
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.004 0.0129 0.0296
Echinococcus multilocularis thioredoxin glutathione reductase 0.0157 0.0674 0.1628
Brugia malayi G-protein coupled receptor 0.004 0.0129 0.0549
Trichomonas vaginalis DNA helicase recq1, putative 0.0043 0.0142 0.1133
Echinococcus granulosus tachykinin peptides receptor 99D 0.004 0.0129 0.0316
Echinococcus granulosus calcium:calmodulin dependent 3'5' cyclic 0.0072 0.0278 0.0678
Trypanosoma cruzi cAMP phosphodiesterase A, putative 0.0072 0.0278 0.4072
Echinococcus granulosus dro:myosuppressin receptor 0.004 0.0129 0.0316
Brugia malayi Dopamine receptor protein 1 0.004 0.0129 0.0549
Echinococcus multilocularis lamin 0.0029 0.008 0.0175
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0039 0.0126 0.0307
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0017 0.0023 0.0265
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.0519 0.2356 0.5752
Loa Loa (eye worm) hypothetical protein 0.0042 0.0138 0.0514
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0072 0.0278 0.0966
Schistosoma mansoni biogenic amine (5HT) receptor 0.004 0.0129 0.0316
Trichomonas vaginalis glucosylceramidase, putative 0.0281 0.1252 1
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0034 0.0101 0.0326
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0072 0.0278 0.0966
Onchocerca volvulus Cathepsin L homolog 0.0018 0.0028 0.0244
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0066 0.0527
Brugia malayi RNA recognition motif domain containing protein 0.0137 0.0583 0.2472
Trypanosoma cruzi cysteine peptidase, putative 0.0018 0.0028 0.0337
Schistosoma mansoni neuropeptide receptor 0.004 0.0129 0.0316
Brugia malayi hypothetical protein 0.0021 0.0043 0.0183
Leishmania major NADH dehydrogenase, putative 0.0014 0.001 0.0072
Trypanosoma brucei 3', 5'-cyclic nucleotide phosphodiesterase, putative 0.0072 0.0278 0.4072
Trypanosoma cruzi DNA damage repair protein, putative 0.0031 0.0088 0.1227
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0029 0.0078 0.0244
Trichomonas vaginalis r2r3-MYB transcription factor, putative 0.0059 0.022 0.1753
Echinococcus multilocularis neuropeptide receptor A26 0.0541 0.2461 0.6001
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0072 0.0278 0.2217
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0072 0.0278 0.2217
Toxoplasma gondii isocitrate dehydrogenase 0.0017 0.0023 0.0047
Echinococcus granulosus tumor protein p63 0.0368 0.1656 0.4043
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0054 0.0196 0.2856
Schistosoma mansoni lipoxygenase 0.0021 0.0043 0.0105
Echinococcus granulosus hyperpolarization activated cyclic 0.0015 0.0013 0.0032
Onchocerca volvulus 0.0018 0.0028 0.0244
Entamoeba histolytica disulphide oxidoreductase, putative 0.0014 0.001 0.0231
Brugia malayi Cathepsin L-like precursor 0.0018 0.0028 0.0119
Brugia malayi Pre-SET motif family protein 0.0228 0.1004 0.4261
Loa Loa (eye worm) hypothetical protein 0.0014 0.001 0.0039
Leishmania major DNA polymerase eta, putative 0.006 0.0224 0.3269
Leishmania major cathepsin L-like protease 0.0018 0.0028 0.0337
Loa Loa (eye worm) hypothetical protein 0.0128 0.0538 0.1998
Schistosoma mansoni hypothetical protein 0.004 0.0129 0.0316
Loa Loa (eye worm) hypothetical protein 0.004 0.0129 0.0481
Loa Loa (eye worm) hypothetical protein 0.004 0.0129 0.0481
Trichomonas vaginalis cGMP-inhibited 3,5-cyclic phosphodiesterase, putative 0.0072 0.0278 0.2217
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0028 0.0224
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0019 0.003 0.0054
Schistosoma mansoni glutamate synthase 0.0014 0.001 0.0025
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0014 0.001 0.0083
Trichomonas vaginalis chromobox protein, putative 0.0041 0.0134 0.107
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0015 0.0013 0.0048
Brugia malayi MH1 domain containing protein 0.0019 0.0033 0.014
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0039 0.0126 0.0161
Schistosoma mansoni hypothetical protein 0.0017 0.0022 0.0055
Loa Loa (eye worm) G-protein coupled receptor 0.004 0.0129 0.0481
Loa Loa (eye worm) MH1 domain-containing protein 0.0016 0.0016 0.0059
Trypanosoma cruzi PAB1-binding protein , putative 0.0077 0.0299 0.4397
Echinococcus multilocularis neuropeptide Y receptor 0.004 0.0129 0.0296
Trypanosoma brucei DNA polymerase kappa, putative 0.0129 0.0543 0.8045
Trypanosoma brucei DNA polymerase kappa, putative 0.0129 0.0543 0.8045
Echinococcus granulosus rhodopsin orphan GPCR 0.004 0.0129 0.0316
Echinococcus granulosus RUN 0.0021 0.0043 0.0105
Onchocerca volvulus 0.0018 0.0028 0.0244
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0883 0.4054 0.9895
Echinococcus granulosus netrin receptor unc 5 0.0014 0.0008 0.002
Trypanosoma cruzi cysteine peptidase, putative 0.0069 0.0267 0.3907
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0017 0.0023 0.0037
Echinococcus multilocularis lipoxygenase domain containing protein 0.0021 0.0043 0.0086
Schistosoma mansoni rab6-interacting 0.0021 0.0043 0.0105
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0006 0.0045
Trichomonas vaginalis penicillin-binding protein, putative 0.0039 0.0126 0.1004
Schistosoma mansoni hypothetical protein 0.0109 0.045 0.1098
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0072 0.0278 0.0966
Onchocerca volvulus 0.0029 0.008 0.0694
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0072 0.0278 0.1178
Toxoplasma gondii cathepsin CPL 0.0018 0.0028 0.0064
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0047 0.0163 0.0398
Schistosoma mansoni amine GPCR 0.004 0.0129 0.0316
Trichomonas vaginalis PIKK family atypical protein kinase 0.0039 0.0124 0.0993
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0072 0.0278 0.4072
Loa Loa (eye worm) heterochromatin protein 1 0.0068 0.026 0.0965
Leishmania major DNA polymerase kappa, putative 0.0107 0.0442 0.6528
Echinococcus granulosus Basic leucine zipper bZIP transcription factor 0.0082 0.0323 0.0788
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0006 0.0045
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.004 0.0129 0.0296
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0017 0.0022 0.0055
Schistosoma mansoni cpg binding protein 0.0063 0.0234 0.0572
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0072 0.0278 0.2217
Schistosoma mansoni smad 0.0035 0.0106 0.0258
Entamoeba histolytica cysteine proteinase, putative 0.0018 0.0028 0.0624
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0025 0.0057 0.0458
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0072 0.0278 0.2217
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0079 0.0633
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0016 0.0017 0.0022
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.059 0.2691 0.6569
Trypanosoma cruzi trypanothione reductase, putative 0.0157 0.0674 1
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0016 0.002 0.0048
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0072 0.0278 0.2217
Brugia malayi Doublecortin family protein 0.0021 0.0043 0.0183
Trichomonas vaginalis r2r3-MYB transcription factor, putative 0.0059 0.022 0.1753
Brugia malayi RE15519p 0.004 0.0129 0.0549
Trichomonas vaginalis PIKK family atypical protein kinase 0.0039 0.0124 0.0993
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0072 0.0278 0.2217
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.002 0.0034 0.0083
Loa Loa (eye worm) hypothetical protein 0.004 0.0129 0.0481
Mycobacterium tuberculosis Probable lipase LipD 0.0039 0.0126 0.0161
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0047 0.0163 0.0379
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0121 0.0963
Trypanosoma cruzi hypothetical protein, conserved 0.0031 0.0088 0.1227
Loa Loa (eye worm) hypothetical protein 0.003 0.0082 0.0306
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.004 0.0129 0.0296
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0054 0.0196 0.0672
Loa Loa (eye worm) hypothetical protein 0.004 0.0129 0.0481
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.004 0.0129 0.0296
Echinococcus granulosus high affinity cAMP specific 3'5' cyclic 0.0072 0.0278 0.0678
Echinococcus granulosus cyclic nucleotide gated cation channel alpha 3 0.0015 0.0013 0.0032
Echinococcus granulosus rhodopsin orphan GPCR 0.004 0.0129 0.0316
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0039 0.0126 0.0307
Schistosoma mansoni opsin-like receptor 0.004 0.0129 0.0316
Trichomonas vaginalis PIKK family atypical protein kinase 0.0049 0.0171 0.1365
Schistosoma mansoni cpg binding protein 0.0063 0.0234 0.0572
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0157 0.0674 0.0927
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0054 0.0196 0.0186
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0113 0.0899
Loa Loa (eye worm) hypothetical protein 0.004 0.0129 0.0481
Plasmodium falciparum DNA repair protein REV1, putative 0.0031 0.0088 0.1163
Brugia malayi beta-lactamase 0.0039 0.0126 0.0533
Brugia malayi Pre-SET motif family protein 0.0034 0.0101 0.0427
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0014 0.0008 0.003
Trypanosoma cruzi NADH dehydrogenase, putative 0.0014 0.001 0.0072
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0015 0.0013 0.0104
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0015 0.0013 0.0032
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0025 0.0057 0.0458
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0029 0.0078 0.033
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0054 0.0196 0.046
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0049 0.0171 0.2476
Echinococcus granulosus intermediate filament protein 0.0029 0.008 0.0195
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0069 0.0267 0.3907
Loa Loa (eye worm) MH2 domain-containing protein 0.0035 0.0106 0.0392
Echinococcus granulosus mixed lineage leukemia protein mll 0.0016 0.0017 0.0042
Trypanosoma brucei hypothetical protein, conserved 0.0039 0.0126 0.1798
Echinococcus multilocularis alpha 1A adrenergic receptor 0.004 0.0129 0.0296
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0029 0.0078 0.0244
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0028 0.0224
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0054 0.0196 0.2856
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0069 0.0267 0.3907
Schistosoma mansoni smad1 5 8 and 0.0035 0.0106 0.0258
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0039 0.0125 0.1781
Loa Loa (eye worm) hypothetical protein 0.0039 0.0126 0.0467
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0054 0.0196 0.2856
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0109 0.045 0.1081
Schistosoma mansoni tar DNA-binding protein 0.0137 0.0583 0.1422
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.002 0.0039 0.0039
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.002 0.0039 0.0494
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0029 0.0078 0.0289
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0025 0.0057 0.0458
Schistosoma mansoni biogenic amine (dopamine) receptor 0.004 0.0129 0.0316
Trichomonas vaginalis MYB3r3, putative 0.0059 0.022 0.1753
Echinococcus granulosus smad 0.0035 0.0106 0.0258
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.006 0.0223 0.0526
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0015 0.0013 0.0012
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0072 0.0278 0.2217
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0016 0.002 0.021
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0014 0.001 0.0005
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0016 0.002 0.021
Echinococcus multilocularis fmrfamide receptor 0.004 0.0129 0.0296
Loa Loa (eye worm) hypothetical protein 0.004 0.0129 0.0481
Mycobacterium tuberculosis Conserved protein 0.0039 0.0126 0.0161
Trypanosoma brucei DNA polymerase kappa, putative 0.0129 0.0543 0.8045
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0054 0.0196 0.0186
Mycobacterium tuberculosis Probable UDP-N-acetylglucosamine 1-carboxyvinyltransferase MurA 0.1552 0.7165 1
Trypanosoma cruzi cyclic nucleotide phosphodiesterase 0.0072 0.0278 0.4072
Brugia malayi Immunoglobulin I-set domain containing protein 0.0014 0.0008 0.0035
Echinococcus multilocularis neuropeptide receptor 0.004 0.0129 0.0296
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0053 0.0188 0.0796
Trypanosoma brucei DNA polymerase kappa, putative 0.0129 0.0543 0.8045
Loa Loa (eye worm) hypothetical protein 0.004 0.0129 0.0481
Leishmania major cathepsin L-like protease 0.0018 0.0028 0.0337
Schistosoma mansoni hypothetical protein 0.0021 0.0043 0.0105
Echinococcus granulosus hyperpolarization activated cyclic 0.0015 0.0013 0.0032
Echinococcus multilocularis musashi 0.0029 0.008 0.0175
Brugia malayi hypothetical protein 0.004 0.0129 0.0549
Plasmodium vivax multidomain scavenger receptor, putative 0.0021 0.0043 0.0511
Schistosoma mansoni tar DNA-binding protein 0.0137 0.0583 0.1422
Echinococcus granulosus hypothetical protein 0.004 0.0129 0.0316
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0228 0.1004 0.3732
Echinococcus granulosus neuropeptide s receptor 0.0541 0.2461 0.6008
Trichomonas vaginalis cAMP/cGMP cyclic nucleotide phosphodiesterase, putative 0.0072 0.0278 0.2217
Loa Loa (eye worm) hypothetical protein 0.004 0.0129 0.0481
Loa Loa (eye worm) Smad1 0.0035 0.0106 0.0392
Schistosoma mansoni histamine h1 receptor 0.004 0.0129 0.0316
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0072 0.0278 0.2217
Echinococcus granulosus dnaJ subfamily B 0.0843 0.3867 0.9439
Schistosoma mansoni DNA polymerase eta 0.0129 0.0545 0.133
Loa Loa (eye worm) RNA binding protein 0.0137 0.0583 0.2165
Echinococcus multilocularis tachykinin peptides receptor 99D 0.004 0.0129 0.0296
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0072 0.0278 0.1178
Trichomonas vaginalis r2r3-MYB transcription factor, putative 0.0059 0.022 0.1753
Echinococcus granulosus neuropeptide Y receptor 0.004 0.0129 0.0316
Brugia malayi larval opioid receptor 0.004 0.0129 0.0549
Loa Loa (eye worm) hypothetical protein 0.004 0.0129 0.0481
Schistosoma mansoni biogenic amine receptor 0.004 0.0129 0.0316
Giardia lamblia DNA damage repair protein 0.0031 0.0088 0.0288
Loa Loa (eye worm) hypothetical protein 0.059 0.2691 1
Loa Loa (eye worm) ctsf protein 0.0018 0.0028 0.0104
Trypanosoma brucei DNA polymerase kappa, putative 0.006 0.0222 0.3245
Giardia lamblia Myb 1-like protein 0.006 0.0221 0.0785
Brugia malayi hypothetical protein 0.004 0.0129 0.0549
Echinococcus granulosus Smad4 0.0035 0.0106 0.0258
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0025 0.0057 0.0458
Echinococcus multilocularis neuropeptides capa receptor 0.004 0.0129 0.0296
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0039 0.0126 0.0467
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0049 0.0171 0.2476
Trichomonas vaginalis mercuric reductase, putative 0.0054 0.0196 0.1568
Echinococcus granulosus Polycystic kidney disease protein 0.0021 0.0043 0.0105
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0017 0.0023 0.0037
Echinococcus granulosus orexin receptor type 2 0.004 0.0129 0.0316
Loa Loa (eye worm) phosphatidylinositol 3 0.0049 0.0171 0.0635
Loa Loa (eye worm) cyclic AMP specific phosphodiesterase PDE4D5A 0.0519 0.2356 0.8757
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0014 0.001 0.0005
Loa Loa (eye worm) hypothetical protein 0.0021 0.0043 0.016
Trypanosoma cruzi DNA polymerase eta, putative 0.0129 0.0545 0.807
Echinococcus multilocularis rhodopsin orphan GPCR 0.004 0.0129 0.0296
Trichomonas vaginalis ap endonuclease, putative 0.002 0.0039 0.0308
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0028 0.0224
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.0072 0.0278 0.0678
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0072 0.0278 0.0966
Schistosoma mansoni netrin receptor unc5 0.0014 0.0008 0.002
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0054 0.0196 0.2816
Chlamydia trachomatis phosphoshikimate 1-carboxyl vinyltransferase 0.0609 0.2778 0.2771
Brugia malayi MH1 domain containing protein 0.0035 0.0106 0.0448
Loa Loa (eye worm) TAR-binding protein 0.0137 0.0583 0.2165
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0281 0.1252 0.4654
Schistosoma mansoni camp-specific cyclic nucleotide phosphodiesterase 0.0072 0.0278 0.0678
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.01 0.0408 0.0997
Loa Loa (eye worm) cysteine protease 0.0018 0.0028 0.0104
Schistosoma mansoni sulfide quinone reductase 0.0014 0.001 0.0025
Brugia malayi MH2 domain containing protein 0.0035 0.0106 0.0448
Echinococcus granulosus beta LACTamase domain containing family member 0.0039 0.0126 0.0307
Echinococcus granulosus cathepsin L cysteine proteinase 0.0018 0.0028 0.0068
Leishmania major trypanothione reductase 0.0157 0.0674 1
Brugia malayi Intermediate filament tail domain containing protein 0.0029 0.008 0.0339
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.002 0.0039 0.0424
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0039 0.0125 0.1781
Mycobacterium tuberculosis Probable esterase LipL 0.0039 0.0126 0.0161
Mycobacterium ulcerans ferredoxin reductase 0.0014 0.001 0.0005
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0006 0.0045
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.059 0.2691 0.6569
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription factor 0.0082 0.0323 0.077
Echinococcus granulosus lipoxygenase domain containing protein 0.0021 0.0043 0.0105
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0018 0.0028 0.0267
Brugia malayi Latrophilin receptor protein 2 0.0017 0.0022 0.0095
Brugia malayi ORL1-like opioid receptor 0.004 0.0129 0.0549
Onchocerca volvulus 0.004 0.0129 0.1124
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0072 0.0278 0.4072
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0029 0.008 0.0297
Loa Loa (eye worm) neuropeptide F receptor 0.004 0.0129 0.0481
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0038 0.0118 0.0941
Loa Loa (eye worm) hypothetical protein 0.0039 0.0126 0.0467
Plasmodium vivax 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0072 0.0278 0.404
Leishmania major DNA polymerase kappa, putative 0.0031 0.0088 0.1227
Onchocerca volvulus 0.0045 0.0152 0.1324
Loa Loa (eye worm) hypothetical protein 0.0029 0.0077 0.0288
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0017 0.0023 0.0057
Brugia malayi Dopamine receptor 0.004 0.0129 0.0549
Brugia malayi Smad1 0.0035 0.0106 0.0448
Brugia malayi Protein kinase domain containing protein 0.0014 0.0008 0.0035
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0016 0.002 0.021
Loa Loa (eye worm) hypothetical protein 0.004 0.0129 0.0481
Loa Loa (eye worm) hypothetical protein 0.0072 0.0278 0.1032
Schistosoma mansoni amine GPCR 0.004 0.0129 0.0316
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0014 0.001 0.0083
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0014 0.001 0.0044
Schistosoma mansoni tar DNA-binding protein 0.0137 0.0583 0.1422
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0014 0.001 0.0072
Schistosoma mansoni calcium/calmodulin-dependent 35-cyclic nucleotide phosphodiesterase 0.0072 0.0278 0.0678
Brugia malayi hypothetical protein 0.0077 0.0299 0.127
Brugia malayi neuropeptide F receptor 0.004 0.0129 0.0549
Brugia malayi hypothetical protein 0.0109 0.045 0.1909
Loa Loa (eye worm) calcium/calmodulin-stimulated cyclic nucleotide phosphodiesterase 0.0072 0.0278 0.1032
Loa Loa (eye worm) hypothetical protein 0.0037 0.0114 0.0425
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0072 0.0278 0.2217
Trichomonas vaginalis glucosylceramidase, putative 0.0185 0.0802 0.6405
Echinococcus multilocularis geminin 0.0892 0.4097 1
Echinococcus granulosus rhodopsin orphan GPCR 0.004 0.0129 0.0316
Trypanosoma brucei hypothetical protein, conserved 0.0072 0.0278 0.4072
Schistosoma mansoni hypothetical protein 0.004 0.0129 0.0316
Trichomonas vaginalis PIKK family atypical protein kinase 0.0016 0.002 0.0156
Brugia malayi AKH receptor 0.004 0.0129 0.0549
Onchocerca volvulus 0.004 0.0129 0.1124
Trichomonas vaginalis MYB, putative 0.006 0.0221 0.1764
Echinococcus multilocularis cathepsin L cysteine protease 0.0018 0.0028 0.0049
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0015 0.0011 0.0026
Schistosoma mansoni chromobox protein 0.0068 0.026 0.0634
Brugia malayi glutamate synthase 0.0014 0.001 0.0044
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0054 0.0196 0.2856
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0049 0.0171 0.2476
Schistosoma mansoni ankyrin 23/unc44 0.0014 0.0008 0.002
Trichomonas vaginalis glucosylceramidase, putative 0.0185 0.0802 0.6405
Loa Loa (eye worm) hypothetical protein 0.004 0.0129 0.0481
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0069 0.0267 0.3907
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0069 0.0267 0.3907
Trichomonas vaginalis glutamate synthase, putative 0.0014 0.001 0.0083
Trichomonas vaginalis glucosylceramidase, putative 0.0185 0.0802 0.6405
Brugia malayi hypothetical protein 0.004 0.0129 0.0549
Echinococcus granulosus jun protein 0.0082 0.0323 0.0788
Onchocerca volvulus 0.004 0.0129 0.1124
Brugia malayi MH1 domain containing protein 0.0019 0.0033 0.014
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0072 0.0278 0.2217
Echinococcus multilocularis g-protein coupled receptor 0.004 0.0129 0.0296
Leishmania major hypothetical protein, conserved 0.0072 0.0278 0.4072
Echinococcus granulosus mothers against decapentaplegic 5 0.0035 0.0106 0.0258
Trichomonas vaginalis C-MYB, putative 0.0059 0.022 0.1753
Leishmania major hypothetical protein, conserved 0.0072 0.0278 0.4072
Echinococcus multilocularis lipoxygenase domain containing protein 0.0021 0.0043 0.0086
Echinococcus multilocularis cysteine protease 0.0018 0.0028 0.0049
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0028 0.0224
Toxoplasma gondii NADPH-glutathione reductase 0.0054 0.0196 0.0672
Schistosoma mansoni glutamate synthase 0.0014 0.001 0.0025
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.01 0.0408 0.0997
Trichomonas vaginalis D-aminoacylase, putative 0.0039 0.0126 0.1004
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0072 0.0278 0.0966
Mycobacterium leprae PROBABLE UDP-N-ACETYLGLUCOSAMINE 1-CARBOXYVINYLTRANSFERASE MURA 0.1552 0.7165 1
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0072 0.0278 0.2217
Giardia lamblia NADH oxidase lateral transfer candidate 0.0054 0.0196 0.0694
Loa Loa (eye worm) hypothetical protein 0.0258 0.1142 0.4243
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0054 0.0196 0.2856
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0358 0.161 0.2235
Trichomonas vaginalis chromobox protein, putative 0.0068 0.026 0.2073
Schistosoma mansoni hypothetical protein 0.0053 0.0188 0.0458
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0054 0.0196 0.2803
Leishmania major cathepsin L-like protease 0.0018 0.0028 0.0337
Trypanosoma cruzi DNA polymerase eta, putative 0.006 0.0224 0.3269
Onchocerca volvulus 0.004 0.0129 0.1124
Trypanosoma brucei DNA polymerase kappa, putative 0.006 0.0222 0.3245
Brugia malayi Cathepsin L-like precursor 0.0018 0.0028 0.0119
Trichomonas vaginalis PIKK family atypical protein kinase 0.0016 0.002 0.0156
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0016 0.0017 0.0042
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0049 0.0171 0.0417
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.002 0.0039 0.0094
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0072 0.0278 0.2217
Schistosoma mansoni tar DNA-binding protein 0.0137 0.0583 0.1422
Trypanosoma cruzi cAMP phosphodiesterase A, putative 0.0072 0.0278 0.4072
Loa Loa (eye worm) hypothetical protein 0.0016 0.0016 0.0059
Plasmodium falciparum phosphodiesterase gamma, putative 0.0072 0.0278 0.4029
Brugia malayi chromobox protein homolog 3 0.0038 0.0121 0.0512
Onchocerca volvulus Glucosylceramidase homolog 0.0185 0.0802 0.6972
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0017 0.0024 0.0191
Loa Loa (eye worm) hypothetical protein 0.004 0.0129 0.0481
Mycobacterium tuberculosis Conserved protein 0.0039 0.0126 0.0161
Echinococcus granulosus lamin dm0 0.0029 0.008 0.0195
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0066 0.0529
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0015 0.0013 0.0032
Plasmodium vivax hypothetical protein, conserved 0.0039 0.0126 0.1753
Loa Loa (eye worm) hypothetical protein 0.004 0.0129 0.0481
Trypanosoma cruzi 2,4-dienoyl-coa reductase fadh1, putative 0.0014 0.001 0.0072
Echinococcus multilocularis neuropeptide receptor 0.004 0.0129 0.0296
Mycobacterium ulcerans DNA polymerase IV 0.0129 0.0543 0.0538
Leishmania major DNA damage repair protein, putative 0.0031 0.0088 0.1227
Brugia malayi putative neuropeptide receptor NPR1 0.004 0.0129 0.0549
Entamoeba histolytica dihydropyrimidine dehydrogenase, putative 0.0014 0.001 0.0231
Echinococcus granulosus mothers against decapentaplegic 2 0.0016 0.0016 0.0039
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0034 0.0101 0.0245
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0069 0.0267 0.3907
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0017 0.0023 0.0057
Echinococcus multilocularis RUN 0.0021 0.0043 0.0086
Echinococcus multilocularis dual 3',5' cyclic AMP and GMP phosphodiesterase 0.0072 0.0278 0.0659
Schistosoma mansoni rhodopsin-like orphan GPCR 0.004 0.0129 0.0316
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0113 0.0899
Echinococcus granulosus sulfide:quinone oxidoreductase 0.0014 0.001 0.0025
Giardia lamblia GTOR 0.0049 0.0171 0.0599
Trypanosoma cruzi cysteine peptidase, putative 0.0069 0.0267 0.3907
Schistosoma mansoni biogenic amine (dopamine) receptor 0.004 0.0129 0.0316
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.004 0.0129 0.0316
Echinococcus multilocularis beta LACTamase domain containing family member 0.0039 0.0126 0.0287
Echinococcus multilocularis neuropeptide Y receptor 0.004 0.0129 0.0296
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0017 0.0022 0.0055
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0006 0.0045
Trypanosoma cruzi DNA polymerase kappa, putative 0.0129 0.0543 0.8045
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0017 0.0023 0.0037
Echinococcus granulosus arachidonate 5 lipoxygenase 0.006 0.0223 0.0544
Schistosoma mansoni biogenic amine receptor 0.004 0.0129 0.0316
Echinococcus multilocularis GPCR, family 2 0.0017 0.0022 0.0035
Loa Loa (eye worm) hypothetical protein 0.0014 0.0007 0.0025
Onchocerca volvulus 0.0021 0.0043 0.0375
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.059 0.2691 0.6562
Trypanosoma brucei DNA polymerase kappa, putative 0.0129 0.0543 0.8045
Trichomonas vaginalis conserved hypothetical protein 0.0072 0.0278 0.2217
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0054 0.0196 0.2856
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0014 0.001 0.0083
Loa Loa (eye worm) isocitrate dehydrogenase 0.0017 0.0023 0.0086
Brugia malayi MH2 domain containing protein 0.0016 0.0016 0.0067
Leishmania major 2,4-dienoyl-coa reductase fadh1, putative 0.0014 0.001 0.0072
Plasmodium falciparum ataxin-2 like protein, putative 0.0077 0.0299 0.4356
Mycobacterium ulcerans lipase LipD 0.0039 0.0126 0.012
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0028 0.0224
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0028 0.0224
Onchocerca volvulus 0.004 0.0129 0.1124
Onchocerca volvulus Cathepsin L homolog 0.0018 0.0028 0.0244
Plasmodium falciparum glutathione reductase 0.0054 0.0196 0.2803
Loa Loa (eye worm) hypothetical protein 0.006 0.0222 0.0826
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0014 0.0009 0.0022
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0014 0.001 0.0231
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0028 0.0224
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0029 0.0078 0.019
Trypanosoma brucei PAB1-binding protein , putative 0.0077 0.0299 0.4397
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0017 0.0023 0.0212
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0034 0.0103 0.0232
Onchocerca volvulus Mothers against decapentaplegic homolog 0.0016 0.0016 0.0137
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0047 0.0163 0.0692
Entamoeba histolytica recQ family helicase, putative 0.0032 0.0091 0.2024
Leishmania major DNA polymerase eta, putative 0.0129 0.0545 0.807
Loa Loa (eye worm) hypothetical protein 0.004 0.0129 0.0481
Echinococcus multilocularis cyclic nucleotide gated cation channel alpha 3 0.0015 0.0013 0.0012
Loa Loa (eye worm) cytochrome P450 family protein 0.0013 0.0006 0.0021
Schistosoma mansoni rhodopsin-like orphan GPCR 0.004 0.0129 0.0316
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0358 0.161 0.2235
Entamoeba histolytica myb-like DNA-binding domain containing protein 0.0059 0.022 0.488
Echinococcus granulosus neuropeptide receptor 0.004 0.0129 0.0316
Schistosoma mansoni voltage-gated potassium channel 0.0019 0.003 0.0074
Onchocerca volvulus 0.0018 0.0028 0.0244
Loa Loa (eye worm) hypothetical protein 0.0039 0.0126 0.0467
Brugia malayi Serotonin/octopamine receptor family protein 7 0.004 0.0129 0.0549
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0015 0.0013 0.0104
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0054 0.0196 0.2803
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0072 0.0278 0.2217
Echinococcus multilocularis high affinity cgmp specific 3' 5' cyclic 0.0072 0.0278 0.0659
Entamoeba histolytica hypothetical protein 0.0109 0.045 1
Echinococcus granulosus pyridine nucleotide disulfide oxidoreductase 0.0014 0.001 0.0025
Loa Loa (eye worm) hypothetical protein 0.0018 0.0028 0.0104
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0069 0.0267 0.3907
Echinococcus multilocularis G protein coupled receptor 139 0.004 0.0129 0.0296
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.004 0.0129 0.0481
Brugia malayi MH2 domain containing protein 0.0512 0.2327 0.9876
Loa Loa (eye worm) hypothetical protein 0.004 0.0129 0.0481
Loa Loa (eye worm) hypothetical protein 0.004 0.0129 0.0481
Toxoplasma gondii Myb family DNA-binding domain-containing protein 0.006 0.0221 0.076
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.004 0.0129 0.1782
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0014 0.001 0.0083
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0035 0.0106 0.0238
Trypanosoma brucei DNA polymerase kappa, putative 0.0129 0.0543 0.8045
Trichomonas vaginalis pc-MYB2, putative 0.0059 0.022 0.1753
Trypanosoma cruzi hypothetical protein, conserved 0.0072 0.0278 0.4072
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.0519 0.2356 0.5744
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.002 0.0034 0.0063
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.0019 0.003 0.0128
Brugia malayi F/Y-rich N-terminus family protein 0.0019 0.0033 0.014
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0049 0.0171 0.0417
Schistosoma mansoni hypothetical protein 0.0017 0.0022 0.0055
Schistosoma mansoni hypothetical protein 0.0037 0.0114 0.0279
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0018 0.0028 0.0227
Leishmania major cathepsin L-like protease 0.0069 0.0267 0.3907
Trichomonas vaginalis PIKK family atypical protein kinase 0.0049 0.0171 0.1365
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0054 0.0196 0.0186
Trypanosoma brucei NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0014 0.001 0.0072
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0072 0.0278 0.2217
Brugia malayi GnHR receptor homolog 0.004 0.0129 0.0549
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0049 0.0171 0.2476
Loa Loa (eye worm) hypothetical protein 0.0072 0.0278 0.1032
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0006 0.0045
Giardia lamblia Sgs1 DNA helicase, putative 0.0029 0.0078 0.0252
Echinococcus multilocularis sex peptide receptor 0.004 0.0129 0.0296
Echinococcus multilocularis calcium:calmodulin dependent 3',5' cyclic 0.0072 0.0278 0.0659
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0072 0.0278 0.0966
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0072 0.0278 0.2217
Plasmodium falciparum ataxin-2 like protein, putative 0.0077 0.0299 0.4356
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0015 0.0013 0.0032
Brugia malayi Tachykinin-like peptides receptor 99D 0.004 0.0129 0.0549
Echinococcus granulosus allatostatin A receptor 0.004 0.0129 0.0316
Trichomonas vaginalis glucosylceramidase, putative 0.0281 0.1252 1
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0034 0.0101 0.0245
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0017 0.0023 0.0265
Plasmodium vivax thioredoxin reductase, putative 0.0157 0.0674 1
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0054 0.0196 0.0833
Loa Loa (eye worm) hypothetical protein 0.004 0.0129 0.0481
Toxoplasma gondii ImpB/MucB/SamB family protein 0.006 0.0224 0.0772
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0025 0.006 0.0179
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0028 0.0224
Plasmodium falciparum thioredoxin reductase 0.0157 0.0674 1
Mycobacterium ulcerans beta-lactamase 0.0039 0.0126 0.012
Loa Loa (eye worm) hypothetical protein 0.0019 0.0033 0.0123
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0029 0.0078 0.033
Trypanosoma cruzi DNA polymerase kappa, putative 0.0129 0.0543 0.8045
Loa Loa (eye worm) hypothetical protein 0.0034 0.0101 0.0374
Trypanosoma cruzi major cysteine proteinase, putative 0.0055 0.0197 0.2871
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0054 0.0196 0.026
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0066 0.0527
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.01 0.0408 0.1517
Echinococcus granulosus TGF beta signal transducer SmadC 0.0035 0.0106 0.0258
Trypanosoma brucei DNA polymerase kappa, putative 0.0129 0.0543 0.8045
Trypanosoma cruzi DNA polymerase kappa, putative 0.0129 0.0543 0.8045
Mycobacterium tuberculosis Conserved protein 0.0039 0.0126 0.0161
Brugia malayi Cathepsin L-like precursor 0.0018 0.0028 0.0119
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.0029 0.0078 0.1017
Trichomonas vaginalis chromobox protein, putative 0.0068 0.026 0.2073
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.004 0.0129 0.0316
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0072 0.0278 0.2217
Mycobacterium ulcerans 3-phosphoshikimate 1-carboxyvinyltransferase 0.0609 0.2778 0.2774
Brugia malayi Thioredoxin reductase 0.0157 0.0674 0.2859
Giardia lamblia CAMP-specific 3,5-cyclic phosphodiesterase 4B 0.059 0.2691 1
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0072 0.0276 0.0655
Echinococcus granulosus serotonin receptor 0.004 0.0129 0.0316
Echinococcus multilocularis rhodopsin orphan GPCR 0.004 0.0129 0.0296
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0066 0.0529
Leishmania major hypothetical protein, conserved 0.0039 0.0126 0.1798
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0072 0.0278 0.0966
Trypanosoma brucei hypothetical protein, conserved 0.0031 0.0088 0.1227
Trichomonas vaginalis glucosylceramidase, putative 0.0281 0.1252 1
Schistosoma mansoni blooms syndrome DNA helicase 0.0015 0.0012 0.0029
Trichomonas vaginalis DNA polymerase eta, putative 0.0129 0.0543 0.4337
Echinococcus granulosus g protein coupled receptor 0.004 0.0129 0.0316
Echinococcus granulosus G protein coupled receptor 139 0.004 0.0129 0.0316
Echinococcus granulosus GPCR family 2 0.0017 0.0022 0.0055
Loa Loa (eye worm) hypothetical protein 0.004 0.0129 0.0481
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.004 0.0129 0.0549
Mycobacterium ulcerans esterase/lipase LipP 0.0039 0.0126 0.012
Echinococcus multilocularis g protein coupled receptor 0.004 0.0129 0.0296
Echinococcus multilocularis cpg binding protein 0.0063 0.0234 0.0553
Echinococcus granulosus mothers against decapentaplegic 6 0.0016 0.0016 0.0039
Leishmania major hypothetical protein, conserved 0.0077 0.0299 0.4397
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.004 0.0129 0.0296
Trypanosoma brucei chrX additional, unordered contigs 0.0031 0.0088 0.1227
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0032 0.0091 0.128
Trichomonas vaginalis glutathione reductase, putative 0.0054 0.0196 0.1568
Entamoeba histolytica cysteine proteinase, putative 0.0018 0.0028 0.0624
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0039 0.0126 0.0533
Schistosoma mansoni DNA helicase recq5 0.0029 0.0078 0.019
Schistosoma mansoni Smad4 0.0035 0.0106 0.0258
Schistosoma mansoni ap endonuclease 0.002 0.0039 0.0094
Schistosoma mansoni intermediate filament proteins 0.0029 0.008 0.0195
Schistosoma mansoni transcription factor LCR-F1 0.0109 0.045 0.1098
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.004 0.0129 0.0549
Schistosoma mansoni polycystin 1-related 0.0021 0.0043 0.0105
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0072 0.0278 0.0678
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0028 0.0224
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0028 0.0224
Trichomonas vaginalis conserved hypothetical protein 0.0072 0.0278 0.2217
Treponema pallidum UDP-N-acetylglucosamine 1-carboxyvinyltransferase 0.2161 1 1
Echinococcus multilocularis chromobox protein 1 0.0068 0.026 0.0615
Schistosoma mansoni hypothetical protein 0.0014 0.001 0.0025
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.002 0.0039 0.0074
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0028 0.0224
Brugia malayi hypothetical protein 0.004 0.0129 0.0549
Echinococcus multilocularis neuropeptides capa receptor 0.004 0.0129 0.0296
Schistosoma mansoni glutamate synthase 0.0014 0.001 0.0025
Loa Loa (eye worm) phosphatidylinositol 3 0.0016 0.002 0.0073
Brugia malayi beta-lactamase family protein 0.0039 0.0126 0.0533
Echinococcus granulosus death domain containing protein 0.0014 0.0008 0.002
Loa Loa (eye worm) hypothetical protein 0.0014 0.0008 0.003
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0029 0.0078 0.017
Echinococcus granulosus tm gpcr rhodopsin 0.004 0.0129 0.0316
Echinococcus granulosus g protein coupled receptor 0.004 0.0129 0.0316
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0014 0.001 0.0083
Brugia malayi mothers against decapentaplegic homolog 3 0.0016 0.0016 0.0067
Trichomonas vaginalis esterase, putative 0.0039 0.0126 0.1004
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0079 0.0633
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0034 0.0101 0.0245
Trypanosoma brucei trypanothione reductase 0.0157 0.0674 1
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0018 0.0028 0.0049
Brugia malayi Probable 3',5'-cyclic phosphodiesterase T04D3.3, putative 0.0072 0.0278 0.1178
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0047 0.0163 0.0606
Plasmodium falciparum cGMP-specific phosphodiesterase 0.0072 0.0278 0.4029
Trypanosoma cruzi DNA polymerase kappa, putative 0.0129 0.0543 0.8045
Loa Loa (eye worm) hypothetical protein 0.0019 0.003 0.0112
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0054 0.0196 0.2816
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0069 0.0267 0.3907
Echinococcus multilocularis rhodopsin orphan GPCR 0.004 0.0129 0.0296
Trichomonas vaginalis glucosylceramidase, putative 0.0281 0.1252 1
Treponema pallidum exodeoxyribonuclease (exoA) 0.002 0.0039 0.0028
Mycobacterium ulcerans DNA polymerase IV 0.0129 0.0543 0.0538
Schistosoma mansoni biogenic amine receptor 0.004 0.0129 0.0316
Echinococcus granulosus nuclear factor of activated T cells 5 0.0072 0.0276 0.0674
Entamoeba histolytica recQ family helicase, putative 0.0014 0.0009 0.0205
Brugia malayi glutathione reductase 0.0157 0.0674 0.2859
Loa Loa (eye worm) hypothetical protein 0.004 0.0129 0.0481
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0018 0.0028 0.0224
Onchocerca volvulus 0.004 0.0129 0.1124
Loa Loa (eye worm) MH1 domain-containing protein 0.0035 0.0106 0.0392
Mycobacterium ulcerans glutamate synthase subunit beta 0.0014 0.001 0.0005
Loa Loa (eye worm) glutathione reductase 0.0157 0.0674 0.2504
Schistosoma mansoni jun-related protein 0.0066 0.0252 0.0614
Echinococcus granulosus cAMP and cAMP inhibited cGMP 3'5' cyclic 0.0072 0.0278 0.0678
Echinococcus granulosus 7TM GPCR rhodopsin 0.004 0.0129 0.0316
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0281 0.1252 0.5314
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0072 0.0278 0.0966
Brugia malayi intermediate filament protein 0.0029 0.008 0.0339
Echinococcus granulosus lamin 0.0029 0.008 0.0195
Echinococcus granulosus bloom syndrome protein 0.0043 0.0142 0.0346
Brugia malayi ImpB/MucB/SamB family protein 0.01 0.0408 0.1733
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.059 0.2691 0.6562
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0015 0.0011 0.0006
Brugia malayi isocitrate dehydrogenase 0.0017 0.0023 0.0099
Loa Loa (eye worm) hypothetical protein 0.004 0.0129 0.0481
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.004 0.0129 0.0549
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.01 0.0408 0.0979
Trypanosoma brucei cAMP-specific phosphodiesterase 0.0072 0.0278 0.4072
Brugia malayi Heterochromatin protein 1 0.0068 0.026 0.1102
Onchocerca volvulus 0.0054 0.0194 0.1685
Trypanosoma brucei DNA polymerase eta, putative 0.0129 0.0545 0.807
Trichomonas vaginalis C-MYB, putative 0.0059 0.022 0.1753
Onchocerca volvulus 0.0021 0.0043 0.0375
Schistosoma mansoni hypothetical protein 0.0892 0.4097 1
Trypanosoma brucei unspecified product 0.0069 0.0264 0.3867
Plasmodium falciparum glutathione reductase 0.0157 0.0674 1
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0063 0.0239 0.3487
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.004 0.0129 0.0296
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0072 0.0278 0.2217
Schistosoma mansoni lamin 0.0029 0.008 0.0195
Toxoplasma gondii histone lysine methyltransferase SET1 0.0113 0.0471 0.1663
Brugia malayi hypothetical protein 0.0021 0.0043 0.0183
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0018 0.0028 0.0104
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.004 0.0129 0.0481
Echinococcus multilocularis bloom syndrome protein 0.0043 0.0142 0.0327
Trichomonas vaginalis penicillin-binding protein, putative 0.0039 0.0126 0.1004
Brugia malayi cytoplasmic intermediate filament protein 0.0016 0.0016 0.007
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0072 0.0278 0.0966
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.004 0.0129 0.0296
Treponema pallidum NADH oxidase 0.0054 0.0196 0.0186
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0006 0.0045
Brugia malayi Cyclic-nucleotide gated cation channel 0.0015 0.0013 0.0055
Loa Loa (eye worm) hypothetical protein 0.004 0.0129 0.0481
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0113 0.0899
Loa Loa (eye worm) hypothetical protein 0.0014 0.0007 0.0025
Mycobacterium tuberculosis Probable dehydrogenase 0.0358 0.161 0.2235
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.004 0.0129 0.0316
Loa Loa (eye worm) beta-lactamase 0.0039 0.0126 0.0467
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0028 0.0224
Schistosoma mansoni 60S ribosomal protein L21 0.0013 0.0005 0.0013
Echinococcus granulosus alpha 1A adrenergic receptor 0.004 0.0129 0.0316
Echinococcus multilocularis neuropeptide s receptor 0.0541 0.2461 0.6001
Echinococcus granulosus cpg binding protein 0.0063 0.0234 0.0572
Trypanosoma cruzi hypothetical protein, conserved 0.0072 0.0278 0.4072
Trypanosoma cruzi DNA damage repair protein, putative 0.0031 0.0088 0.1227
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0006 0.0045
Echinococcus multilocularis sulfide:quinone oxidoreductase 0.0014 0.001 0.0005
Loa Loa (eye worm) fibroinase 0.0018 0.0028 0.0104
Loa Loa (eye worm) hypothetical protein 0.004 0.0129 0.0481
Trypanosoma cruzi NADH dehydrogenase, putative 0.0014 0.001 0.0072
Trichomonas vaginalis PIKK family atypical protein kinase 0.0016 0.002 0.0156
Brugia malayi Serotonin receptor 0.004 0.0129 0.0549
Trypanosoma brucei cAMP-specific phosphodiesterase 0.0072 0.0278 0.4072
Echinococcus multilocularis dna polymerase kappa 0.0129 0.0543 0.1308
Trypanosoma brucei DNA polymerase IV, putative 0.0122 0.051 0.7545
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0006 0.0045
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0398 0.1796 0.2495
Loa Loa (eye worm) neuropeptide F receptor 0.004 0.0129 0.0481
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0015 0.0012 0.0005
Brugia malayi Dopamine receptor protein 2 0.004 0.0129 0.0549
Loa Loa (eye worm) cytochrome P450 family protein 0.0013 0.0006 0.0021
Loa Loa (eye worm) hypothetical protein 0.004 0.0129 0.0481
Onchocerca volvulus 0.0029 0.008 0.0694
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0069 0.0549
Trichomonas vaginalis calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0072 0.0278 0.2217
Schistosoma mansoni neuropeptide f receptor 76f 0.004 0.0129 0.0316
Loa Loa (eye worm) hypothetical protein 0.004 0.0129 0.0481
Schistosoma mansoni myosin xvIII 0.004 0.0129 0.0316
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0049 0.0171 0.0398
Echinococcus granulosus calcium:calmodulin dependent 3'5' cyclic 0.0072 0.0278 0.0678
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0041 0.0134 0.1165
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0017 0.0023 0.0018
Mycobacterium ulcerans monoxygenase 0.0014 0.001 0.0005
Onchocerca volvulus 0.0018 0.0028 0.0244
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0014 0.0009 0.0021
Loa Loa (eye worm) hypothetical protein 0.0015 0.0013 0.0048
Trichomonas vaginalis D-aminoacylase, putative 0.0039 0.0126 0.1004
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.004 0.0129 0.0316
Onchocerca volvulus 0.0018 0.0028 0.0244
Trypanosoma cruzi hypothetical protein, conserved 0.0039 0.0126 0.1798
Schistosoma mansoni smad1 5 8 and 0.0035 0.0106 0.0258
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.0038 0.0121 0.04
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0072 0.0278 0.2217
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.0072 0.0278 0.0678
Loa Loa (eye worm) hypothetical protein 0.004 0.0129 0.0481
Entamoeba histolytica myb-like DNA-binding domain containing protein 0.0059 0.022 0.488
Brugia malayi exodeoxyribonuclease III family protein 0.002 0.0039 0.0163
Echinococcus granulosus neuropeptides capa receptor 0.004 0.0129 0.0316
Loa Loa (eye worm) G-protein coupled receptor 0.004 0.0129 0.0481
Trichomonas vaginalis glucosylceramidase, putative 0.0185 0.0802 0.6405
Leishmania major 2,4-dienoyl-coa reductase-like protein 0.0014 0.001 0.0072
Entamoeba histolytica cysteine protease, putative 0.0018 0.0028 0.0624
Onchocerca volvulus 0.0059 0.0219 0.1901
Trichomonas vaginalis PIKK family atypical protein kinase 0.0039 0.0124 0.0993
Echinococcus multilocularis Smad4 0.0035 0.0106 0.0238
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0025 0.0057 0.0458
Echinococcus multilocularis tumor protein p63 0.0368 0.1656 0.4031
Trypanosoma brucei unspecified product 0.0069 0.0264 0.3867
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0054 0.0196 0.2856
Entamoeba histolytica hypothetical protein 0.0109 0.045 1
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.004 0.0129 0.0481
Trichomonas vaginalis pc-MYB2, putative 0.0059 0.022 0.1753
Loa Loa (eye worm) CYP4Cod1 0.0013 0.0006 0.0021
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprA 0.0014 0.001 0.0005
Echinococcus granulosus NADPH:adrenodoxin oxidoreductase 0.0014 0.001 0.0025
Loa Loa (eye worm) hypothetical protein 0.004 0.0129 0.0481
Echinococcus multilocularis smad 0.0035 0.0106 0.0238
Echinococcus multilocularis dro:myosuppressin receptor 0.004 0.0129 0.0296
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0072 0.0278 0.2217
Schistosoma mansoni hypothetical protein 0.0066 0.0252 0.0614
Mycobacterium ulcerans thioredoxin reductase TrxB2 0.0014 0.001 0.0005
Loa Loa (eye worm) hypothetical protein 0.0014 0.0009 0.0032
Loa Loa (eye worm) pyridine nucleotide-disufhide oxidoreductase 0.0014 0.001 0.0039
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0019 0.003 0.0074
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.002 0.0039 0.0494
Onchocerca volvulus 0.0039 0.0126 0.1092
Schistosoma mansoni adenoreceptor 0.004 0.0129 0.0316
Loa Loa (eye worm) hypothetical protein 0.0029 0.008 0.0297
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0014 0.001 0.0044
Echinococcus multilocularis Ankyrin 0.0014 0.0009 0.0001
Trypanosoma brucei DNA polymerase kappa, putative 0.0076 0.0297 0.4368
Echinococcus multilocularis rhodopsin orphan GPCR 0.004 0.0129 0.0296
Plasmodium falciparum 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0072 0.0278 0.4029
Echinococcus multilocularis cAMP and cAMP inhibited cGMP 3',5' cyclic 0.0072 0.0278 0.0659
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0017 0.0022 0.0035
Echinococcus granulosus 7tm_1 domain containing protein 0.004 0.0129 0.0316
Onchocerca volvulus Cathepsin F homolog 0.0018 0.0028 0.0244
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0078 0.0622
Echinococcus granulosus dual 3'5' cyclic AMP and GMP phosphodiesterase 0.0072 0.0278 0.0678
Onchocerca volvulus 0.0018 0.0028 0.0244
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0038 0.0118 0.0941
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0069 0.0267 0.3907
Echinococcus multilocularis high affinity cAMP specific 3',5' cyclic 0.0072 0.0278 0.0659
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.06 0.2736 0.9847
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0016 0.002 0.0028
Trypanosoma cruzi hypothetical protein, conserved 0.0031 0.0088 0.1227
Loa Loa (eye worm) hypothetical protein 0.004 0.0129 0.0481
Plasmodium vivax vivapain-2 0.0018 0.0028 0.0284
Echinococcus multilocularis voltage gated potassium channel 0.0019 0.003 0.0054
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0082 0.0323 0.1129
Giardia lamblia Hypothetical protein 0.0072 0.0278 0.0997
Loa Loa (eye worm) TYRA-2 protein 0.004 0.0129 0.0481
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0039 0.0126 0.0161
Brugia malayi NADPH:adrenodoxin oxidoreductase, mitochondrial precursor 0.0014 0.001 0.0044
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0015 0.0013 0.0032
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0006 0.0045
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0032 0.0091 0.128
Loa Loa (eye worm) transcription factor SMAD2 0.0512 0.2327 0.8648
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0072 0.0278 0.0966
Toxoplasma gondii thioredoxin reductase 0.0157 0.0674 0.2397
Schistosoma mansoni rhodopsin-like orphan GPCR 0.004 0.0129 0.0316
Schistosoma mansoni hypothetical protein 0.0014 0.0008 0.002
Trichomonas vaginalis dihydropyrimidine dehydrogenase, putative 0.0014 0.001 0.0083
Echinococcus granulosus rhodopsin orphan GPCR 0.004 0.0129 0.0316
Loa Loa (eye worm) hypothetical protein 0.0021 0.0043 0.016
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0016 0.0017 0.0022
Trichomonas vaginalis glucosylceramidase, putative 0.0195 0.0848 0.6775
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0028 0.0224
Trichomonas vaginalis apoptosis inducing factor, putative 0.0014 0.001 0.0083
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.004 0.0129 0.0316
Echinococcus granulosus cathepsin l cysteine peptidase 0.0018 0.0028 0.0068
Toxoplasma gondii LsmAD domain-containing protein 0.0077 0.0299 0.1044
Loa Loa (eye worm) thioredoxin reductase 0.0157 0.0674 0.2504
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0072 0.0278 0.2217
Brugia malayi follicle stimulating hormone receptor 0.0291 0.1295 0.5497
Leishmania major phosphatidylinositol 3-kinase, putative 0.0016 0.002 0.021
Brugia malayi CXXC zinc finger family protein 0.0059 0.0219 0.0928
Schistosoma mansoni disulfide oxidoreductase 0.0014 0.001 0.0025
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0113 0.0899
Plasmodium vivax DNA repair protein REV1, putative 0.0031 0.0088 0.1179
Echinococcus granulosus sex peptide receptor 0.004 0.0129 0.0316
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.004 0.0129 0.0316
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0015 0.0013 0.0032
Trypanosoma brucei unspecified product 0.0122 0.051 0.7545
Brugia malayi hypothetical protein 0.004 0.0129 0.0549
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0031 0.0088 0.0279
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.002 0.0039 0.0494
Loa Loa (eye worm) hypothetical protein 0.004 0.0129 0.0481
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0025 0.0057 0.0458
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0018 0.0028 0.0104
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0054 0.0196 0.2856
Brugia malayi Death domain containing protein 0.0014 0.0008 0.0035
Trypanosoma brucei DNA damage repair protein, putative 0.0031 0.0088 0.1227
Toxoplasma gondii shikimate dehydrogenase substrate binding domain-containing protein 0.0609 0.2778 1
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprA 0.0014 0.001 0.0005
Trypanosoma brucei NADH dehydrogenase 0.0014 0.001 0.0072
Wolbachia endosymbiont of Brugia malayi UDP-N-acetylglucosamine 1-carboxyvinyltransferase 0.2161 1 1
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0054 0.0196 0.0191
Echinococcus granulosus histone lysine methyltransferase setb 0.0034 0.0101 0.0245
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0054 0.0194 0.072
Brugia malayi MH2 domain containing protein 0.0035 0.0106 0.0448
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0054 0.0196 0.0479
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0054 0.0196 0.2856
Trichomonas vaginalis chromobox protein, putative 0.0041 0.0134 0.107
Echinococcus multilocularis hyperpolarization activated cyclic 0.0015 0.0013 0.0012
Schistosoma mansoni neuropeptide receptor 0.004 0.0129 0.0316
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0398 0.1796 0.2495
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0079 0.0633
Brugia malayi Cytochrome P450 family protein 0.0013 0.0006 0.0023
Echinococcus granulosus peptide allatostatin:somatostatin 0.004 0.0129 0.0316
Trichomonas vaginalis glucosylceramidase, putative 0.0281 0.1252 1
Trypanosoma brucei cAMP phosphodiesterase A, putative 0.0072 0.0278 0.4072
Echinococcus multilocularis serotonin receptor 0.004 0.0129 0.0296
Plasmodium falciparum cGMP-specific phosphodiesterase 0.0072 0.0278 0.4029
Brugia malayi Papain family cysteine protease containing protein 0.0018 0.0028 0.0119
Loa Loa (eye worm) hypothetical protein 0.004 0.0129 0.0481
Loa Loa (eye worm) hypothetical protein 0.0039 0.0126 0.0467
Loa Loa (eye worm) hypothetical protein 0.004 0.0129 0.0481
Onchocerca volvulus 0.0259 0.1151 1
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0018 0.0028 0.0267
Echinococcus multilocularis potassium:sodium hyperpolarization activated 0.0015 0.0013 0.0012
Trypanosoma brucei DNA polymerase kappa, putative 0.0129 0.0543 0.8045
Echinococcus multilocularis glutamate synthase 0.0014 0.001 0.0005
Trypanosoma brucei hypothetical protein, conserved 0.0014 0.001 0.0072
Giardia lamblia hypothetical protein 0.0072 0.0278 0.0997
Onchocerca volvulus 0.0018 0.0028 0.0244
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.004 0.0129 0.0316
Echinococcus granulosus voltage gated potassium channel 0.0019 0.003 0.0074
Schistosoma mansoni rab6-interacting 0.0021 0.0043 0.0105
Echinococcus multilocularis pyridine nucleotide disulfide oxidoreductase 0.0014 0.001 0.0005
Echinococcus granulosus glutamate synthase 0.0014 0.001 0.0025
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.004 0.0129 0.0316
Onchocerca volvulus 0.004 0.0129 0.1124
Trichomonas vaginalis glucosylceramidase, putative 0.0195 0.0848 0.6775
Onchocerca volvulus 0.004 0.0129 0.1124
Mycobacterium leprae Probable lipase LipE 0.0039 0.0126 0.0161
Echinococcus multilocularis serotonin receptor 0.004 0.0129 0.0296
Brugia malayi hypothetical protein 0.004 0.0129 0.0549
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0072 0.0278 0.0678
Toxoplasma gondii target of rapamycin (TOR), putative 0.0036 0.0113 0.0369
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0072 0.0278 0.2217
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0066 0.0527
Brugia malayi ImpB/MucB/SamB family protein 0.0129 0.0545 0.2312
Schistosoma mansoni hypothetical protein 0.0017 0.0022 0.0055
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0072 0.0278 0.2217
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.004 0.0129 0.0481
Schistosoma mansoni Smad4 0.0016 0.0016 0.0039
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0072 0.0278 0.1178
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0072 0.0278 0.0966
Schistosoma mansoni smad 0.0016 0.0016 0.0039
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0054 0.0196 0.2856
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0015 0.0013 0.0032
Brugia malayi hypothetical protein 0.004 0.0129 0.0549
Trypanosoma brucei cAMP-specific phosphodiesterase, putative 0.0072 0.0278 0.4072
Schistosoma mansoni voltage-gated potassium channel 0.0015 0.0013 0.0032
Trypanosoma cruzi hypothetical protein, conserved 0.0072 0.0278 0.4072
Schistosoma mansoni loxhd1 0.0021 0.0043 0.0105
Trichomonas vaginalis glucosylceramidase, putative 0.0281 0.1252 1
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprB 0.0014 0.001 0.0005
Echinococcus multilocularis calcium:calmodulin dependent 3',5' cyclic 0.0072 0.0278 0.0659
Echinococcus multilocularis mothers against decapentaplegic 6 0.0016 0.0016 0.0019
Echinococcus multilocularis fmrfamide receptor 0.004 0.0129 0.0296
Echinococcus granulosus apoptosis inducing factor 1 mitochondrial 0.0014 0.001 0.0025
Onchocerca volvulus 0.0064 0.0241 0.2097

Activities

Activity type Activity value Assay description Source Reference
K (ADMET) = 0.01 min-1 Pseudo first-order rate constant (K) for disappearance of compound from rat 10% brain homogenate ChEMBL. 2754705
K (ADMET) = 0.051 min-1 Pseudo first-order rate constant (K) for disappearance of compound from dog whole blood ChEMBL. 2754705
K (ADMET) = 0.115 min-1 Pseudo first-order rate constant (K) for disappearance of compound from rat whole blood ChEMBL. 2754705
T1/2 (ADMET) = 6 min Half-life for disappearance of compound from rat whole blood ChEMBL. 2754705
T1/2 (ADMET) = 13.5 min Half-life for disappearance of compound from dog whole blood ChEMBL. 2754705
T1/2 (ADMET) = 73.4 min Half-life for disappearance of compound from rat 10% brain homogenate ChEMBL. 2754705

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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